Detailed information for compound 402287

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 2231.87 | Formula: C68H102Na16O43S8
  • H donors: 0 H acceptors: 32 LogP: 10.45 Rotable bonds: 76
    Rule of 5 violations (Lipinski): 3
  • SMILES: [O-]C(=O)CC(C(=O)[O-])SCCCOC1C(OC2OC(COCCCSC(C(=O)[O-])CC(=O)[O-])C(C(C2OCCCSC(C(=O)[O-])CC(=O)[O-])OCCCSC(C(=O)[O-])CC(=O)[O-])OCCCSC(C(=O)[O-])CC(=O)[O-])C(COCCCSC(C(=O)[O-])CC(=O)[O-])OC(C1OCCCSC(C(=O)[O-])CC(=O)[O-])OCCCSC(C(=O)[O-])CC(=O)[O-].[NaH+].[NaH+].[NaH+].[NaH+].[NaH+].[NaH+].[NaH+].[NaH+].[NaH+].[NaH+].[NaH+].[NaH+].[NaH+].[NaH+].[NaH+].[NaH+]
  • InChi: 1S/C68H102O43S8.16Na/c69-45(70)25-37(59(85)86)112-17-1-9-101-33-35-53(103-11-3-19-114-39(61(89)90)27-47(73)74)55(104-12-4-20-115-40(62(91)92)28-48(75)76)58(107-15-7-23-118-43(65(97)98)31-51(81)82)68(110-35)111-54-36(34-102-10-2-18-113-38(60(87)88)26-46(71)72)109-67(108-16-8-24-119-44(66(99)100)32-52(83)84)57(106-14-6-22-117-42(64(95)96)30-50(79)80)56(54)105-13-5-21-116-41(63(93)94)29-49(77)78;;;;;;;;;;;;;;;;/h35-44,53-58,67-68H,1-34H2,(H,69,70)(H,71,72)(H,73,74)(H,75,76)(H,77,78)(H,79,80)(H,81,82)(H,83,84)(H,85,86)(H,87,88)(H,89,90)(H,91,92)(H,93,94)(H,95,96)(H,97,98)(H,99,100);;;;;;;;;;;;;;;;/q;16*+1/p-16
  • InChiKey: OOOQDKWTWZWMMG-UHFFFAOYSA-A  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0542 0.1123 0.1216
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0235 0.0461 0.0883
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0088 0.0143 0.0277
Loa Loa (eye worm) hypothetical protein 0.0764 0.1601 0.174
Trypanosoma cruzi histone deacetylase, putative 0.0042 0.0045 0.004
Trypanosoma cruzi kinesin, putative 0.0555 0.1152 0.1244
Echinococcus multilocularis hypothetical protein 0.0944 0.1991 0.1991
Loa Loa (eye worm) hypothetical protein 0.004 0.0039 0.0042
Loa Loa (eye worm) hypothetical protein 0.0037 0.0033 0.0035
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0012 0.0013
Leishmania major hypothetical protein, conserved 0.0116 0.0204 0.0343
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0043 0.0084
Brugia malayi hypothetical protein 0.0026 0.0008 0.0009
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0208 0.0403 0.0694
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0235 0.0461 0.0888
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0032 0.0016
Plasmodium falciparum serine repeat antigen 1 0.0542 0.1123 0.2152
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.004 0.0039 0.007
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0698 0.1461 0.158
Loa Loa (eye worm) hypothetical protein 0.0035 0.0028 0.0031
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0057 0.0093
Brugia malayi calpain 5 0.0389 0.0793 0.0861
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0032 0.0023 0.0027
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0064 0.0092 0.0147
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0032 0.0062
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0023 0.0044
Schistosoma mansoni caspase-7 (C14 family) 0.0061 0.0085 0.0087
Brugia malayi Serine protease Z688.6 precursor 0.0042 0.0043 0.0047
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0542 0.1123 0.2165
Onchocerca volvulus 0.0029 0.0016 0.0021
Loa Loa (eye worm) peptidase C13 family protein 0.0149 0.0276 0.03
Echinococcus granulosus beta-adrenergic receptor kinase 0.004 0.0039 0.0039
Brugia malayi Calmodulin-like protein 0.0116 0.0204 0.0221
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Brugia malayi PXA domain containing protein 0.004 0.0039 0.0042
Loa Loa (eye worm) proteasome subunit beta type 2 0.004 0.0039 0.0043
Echinococcus multilocularis calpain family protein 1, d 0.1608 0.3425 0.3425
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.0024 0.0026
Entamoeba histolytica histone deacetylase, putative 0.0088 0.0143 0.0271
Brugia malayi steroid hormone receptor 0.0031 0.0019 0.0021
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0653 0.1363 0.238
Leishmania major hypothetical protein, conserved 0.0208 0.0403 0.0694
Loa Loa (eye worm) hypothetical protein 0.0042 0.0043 0.0047
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0132 0.0239 0.026
Trypanosoma brucei DNA polymerase eta, putative 0.0045 0.0051 0.0075
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0122 0.0216 0.0364
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0032 0.0035
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0042 0.0043 0.0043
Echinococcus granulosus Transglutaminase 0.0251 0.0496 0.0496
Onchocerca volvulus 0.0061 0.0085 0.0154
Trypanosoma cruzi centrin, putative 0.0124 0.0221 0.0232
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0118 0.0208 0.0221
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Trypanosoma brucei centrin-3 0.0124 0.0221 0.0374
Giardia lamblia Alanyl dipeptidyl peptidase 0.0235 0.0461 0.1218
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0854 0.1797 0.1952
Brugia malayi Steroid receptor seven-up type 2 0.0031 0.0019 0.0021
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0597 0.1243 0.1342
Loa Loa (eye worm) hypothetical protein 0.0037 0.0033 0.0035
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0032 0.0059
Mycobacterium tuberculosis Hypothetical protein 0.0251 0.0496 0.0481
Plasmodium falciparum pyruvate kinase 0.0033 0.0024 0.0031
Echinococcus multilocularis thyroid hormone receptor alpha 0.0158 0.0294 0.0294
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0032 0.0026
Brugia malayi Cathepsin L-like precursor 0.0764 0.1601 0.174
Echinococcus granulosus intermediate filament protein 0.0027 0.0012 0.0012
Entamoeba histolytica hypothetical protein, conserved 0.0032 0.0023 0.0038
Loa Loa (eye worm) hypothetical protein 0.0026 0.0008 0.0009
Onchocerca volvulus 0.0045 0.005 0.0087
Leishmania major centrin, putative 0.0116 0.0204 0.0343
Brugia malayi calpain 5 0.0555 0.1152 0.1252
Brugia malayi intermediate filament protein 0.0027 0.0012 0.0013
Brugia malayi PAN domain containing protein 0.0029 0.0016 0.0017
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0138 0.0251 0.0484
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0116 0.0204 0.0217
Echinococcus multilocularis proteasome (prosome, macropain) 0.0083 0.0132 0.0132
Onchocerca volvulus 0.0064 0.0092 0.0169
Trypanosoma cruzi cytochrome P450, putative 0.0045 0.0051 0.0046
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0235 0.0461 0.0496
Onchocerca volvulus Matrix metalloproteinase homolog 0.0053 0.0067 0.012
Echinococcus multilocularis cysteine protease 0.2426 0.5188 0.5188
Brugia malayi Cathepsin L-like precursor 0.2426 0.5188 0.5639
Leishmania major cathepsin L-like protease 0.2663 0.57 1
Schistosoma mansoni retinoic acid receptor RXR 0.0031 0.0019 0.0016
Toxoplasma gondii histone deacetylase HDAC4 0.0042 0.0045 0.0071
Mycobacterium ulcerans lipase LipD 0.0036 0.0032 0.0016
Giardia lamblia Encystation-specific protease 0.0542 0.1123 0.3058
Loa Loa (eye worm) matrixin family protein 0.0053 0.0067 0.0073
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0031 0.0019 0.0021
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.004 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0017
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0016 0.0014
Echinococcus multilocularis regulator of G protein signaling 3 0.004 0.0039 0.0039
Trichomonas vaginalis hypothetical protein 0.0389 0.0793 0.1528
Loa Loa (eye worm) hypothetical protein 0.0036 0.0032 0.0035
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0776 0.1629 0.1766
Onchocerca volvulus 0.0029 0.0016 0.0021
Entamoeba histolytica protein kinase, putative 0.0555 0.1152 0.2216
Echinococcus multilocularis calbindin 32 0.0118 0.0208 0.0208
Echinococcus multilocularis glycogen phosphorylase 0.0105 0.0181 0.0181
Trichomonas vaginalis conserved hypothetical protein 0.0542 0.1123 0.2165
Toxoplasma gondii microneme protein MIC17A 0.0029 0.0016 0.0014
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.071 0.1486 0.2595
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.228 0.4874 0.5294
Schistosoma mansoni hypothetical protein 0.0037 0.0033 0.003
Echinococcus granulosus programmed cell death protein 0.0124 0.0221 0.0221
Brugia malayi A-kinase anchor protein 10, precursor 0.004 0.0039 0.0042
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Schistosoma mansoni glycogen phosphorylase 0.0105 0.0181 0.0192
Loa Loa (eye worm) hypothetical protein 0.0321 0.0646 0.0702
Brugia malayi PAN domain containing protein 0.0029 0.0016 0.0017
Echinococcus granulosus calcium uptake protein 1 0.0118 0.0208 0.0208
Trypanosoma brucei Calpain-like protein CALP1.3 0.0597 0.1243 0.2168
Schistosoma mansoni chromatin regulatory protein sir2 0.0032 0.0023 0.002
Brugia malayi Papain family cysteine protease containing protein 0.1306 0.2771 0.3012
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0046 0.0052 0.0036
Echinococcus granulosus dna polymerase eta 0.0045 0.0051 0.0051
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0944 0.1991 0.2157
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0024 0.0017
Echinococcus granulosus pyruvate kinase 0.0033 0.0024 0.0024
Toxoplasma gondii aldehyde dehydrogenase 0.0122 0.0216 0.04
Trypanosoma brucei calpain, putative 0.0653 0.1363 0.238
Trichomonas vaginalis conserved hypothetical protein 0.0542 0.1123 0.2165
Toxoplasma gondii pyruvate kinase PyK1 0.0033 0.0024 0.0031
Trypanosoma cruzi calpain cysteine peptidase, putative 0.1209 0.2562 0.2777
Schistosoma mansoni glycosylphosphatidylinositol:protein transamidase (C13 family) 0.0035 0.0028 0.0026
Echinococcus granulosus axis inhibition protein axin 0.004 0.0039 0.0039
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0597 0.1243 0.2168
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2663 0.57 1
Schistosoma mansoni histone deacetylase 0.0088 0.0143 0.0151
Brugia malayi hypothetical protein 0.0154 0.0286 0.031
Trichomonas vaginalis calcium binding protein, putative 0.0116 0.0204 0.0393
Trypanosoma brucei calmodulin, putative 0.0118 0.0208 0.0351
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0811 0.1705 0.328
Entamoeba histolytica glycogen phosphorylase, putative 0.0046 0.0052 0.0094
Schistosoma mansoni coup transcription factor 0.0031 0.0019 0.0016
Echinococcus granulosus cathepsin b 0.4285 0.9202 0.9202
Toxoplasma gondii histone deacetylase HDAC1 0.0099 0.0167 0.0306
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0235 0.0461 0.0496
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0037 0.0033 0.003
Schistosoma mansoni chromatin regulatory protein sir2 0.0125 0.0222 0.0237
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Mycobacterium leprae Conserved hypothetical protein 0.0251 0.0496 0.173
Onchocerca volvulus Bile acid receptor homolog 0.0031 0.0019 0.0029
Echinococcus multilocularis musashi 0.0027 0.0012 0.0012
Plasmodium falciparum serine repeat antigen 6 0.0542 0.1123 0.2152
Giardia lamblia Alanyl dipeptidyl peptidase 0.0235 0.0461 0.1218
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0031 0.0019 0.0019
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0305 0.0611 0.0655
Brugia malayi cathepsin Z-like cysteine proteinase 0.0542 0.1123 0.1221
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0019 0.0019
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0032 0.0016
Entamoeba histolytica cysteine proteinase, putative 0.1662 0.354 0.6822
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0122 0.0216 0.0216
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0542 0.1123 0.2152
Brugia malayi beta-lactamase family protein 0.0036 0.0032 0.0035
Onchocerca volvulus Peroxidasin homolog 0.0064 0.0092 0.0169
Trypanosoma brucei pyruvate kinase 1 0.0033 0.0024 0.0028
Mycobacterium tuberculosis Probable oxidoreductase 0.0121 0.0215 0.02
Trypanosoma cruzi I/6 autoantigen, putative 0.0116 0.0204 0.0212
Plasmodium falciparum cysteine proteinase falcipain 3 0.2426 0.5188 1
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0043 0.0084
Trypanosoma brucei unspecified product 0.0208 0.0403 0.0694
Echinococcus multilocularis beta adrenergic receptor kinase 0.004 0.0039 0.0039
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-5 0.0208 0.0403 0.0694
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0235 0.0461 0.0795
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.057 0.1183 0.1277
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0031 0.0019 0.0021
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0597 0.1243 0.1342
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0149 0.0276 0.0532
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0057 0.0057
Giardia lamblia Cathepsin B precursor 0.0542 0.1123 0.3058
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0057 0.0057
Giardia lamblia Cathepsin L precursor 0.0542 0.1123 0.3058
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0567 0.1177 0.1271
Trypanosoma brucei histone deacetylase 4 0.0099 0.0167 0.0278
Echinococcus multilocularis cathepsin L 0.0542 0.1123 0.1123
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0094 0.0098
Trypanosoma brucei Calpain-like protein 2 0.0724 0.1517 0.265
Schistosoma mansoni cathepsin B (C01 family) 0.0542 0.1123 0.1216
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0029 0.0016 0.0014
Leishmania major i/6 autoantigen-like protein 0.0116 0.0204 0.0343
Brugia malayi Cathepsin L-like precursor 0.2426 0.5188 0.5639
Brugia malayi Peroxidasin 0.0064 0.0092 0.01
Echinococcus multilocularis expressed protein 0.0769 0.1614 0.1614
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0939 0.198 0.2144
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0116 0.0204 0.0343
Schistosoma mansoni hypothetical protein 0.0061 0.0085 0.0087
Mycobacterium tuberculosis Long conserved protein 0.0251 0.0496 0.0481
Entamoeba histolytica grainin 2 0.0124 0.0221 0.0421
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0116 0.0204 0.0204
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0257 0.0274
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0017
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0088 0.0143 0.0277
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0042 0.0043 0.0038
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.228 0.4874 0.5294
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0939 0.198 0.3464
Onchocerca volvulus 0.005 0.0062 0.0111
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0216 0.02
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1306 0.2771 0.5341
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0116 0.0204 0.0212
Entamoeba histolytica cysteine protease, putative 0.0542 0.1123 0.2161
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0037 0.0033 0.003
Entamoeba histolytica grainin, putative 0.0118 0.0208 0.0396
Brugia malayi Matrixin family protein 0.0024 0.0005 0.0005
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0125 0.0222 0.0376
Toxoplasma gondii hypothetical protein 0.0029 0.0016 0.0014
Echinococcus granulosus tissue type plasminogen activator 0.0045 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.1775 0.3784 0.4112
Schistosoma mansoni hypothetical protein 0.0116 0.0204 0.0217
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0542 0.1123 0.1221
Echinococcus granulosus regulator of G protein signaling 3 0.004 0.0039 0.0039
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0389 0.0793 0.1528
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0024 0.0038
Onchocerca volvulus 0.0064 0.0092 0.0169
Brugia malayi Proteasome A-type and B-type family protein 0.0083 0.0132 0.0143
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.1135 0.2402 0.4207
Giardia lamblia Transglutaminase/protease, putative 0.0251 0.0496 0.1314
Toxoplasma gondii centrin 0.0116 0.0204 0.0377
Brugia malayi beta-lactamase family protein 0.0036 0.0032 0.0035
Leishmania major cathepsin L-like protease 0.2426 0.5188 0.9102
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Onchocerca volvulus 0.0154 0.0286 0.0542
Loa Loa (eye worm) matrix metalloproteinase 0.0024 0.0005 0.0005
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0122 0.0218 0.0218
Onchocerca volvulus Cathepsin L homolog 0.2426 0.5188 1
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0045 0.005 0.0079
Leishmania major histone deacetylase, putative 0.0099 0.0167 0.0278
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0037 0.0033 0.0035
Onchocerca volvulus 0.0029 0.0016 0.0021
Toxoplasma gondii hypothetical protein 0.0235 0.0461 0.0873
Brugia malayi Trypsin family protein 0.0037 0.0033 0.0035
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.004 0.0039 0.0042
Onchocerca volvulus 0.0037 0.0033 0.0054
Loa Loa (eye worm) prolyl oligopeptidase 0.0811 0.1705 0.1853
Plasmodium vivax GPI-anchor transamidase, putative 0.0035 0.0028 0.0038
Loa Loa (eye worm) hypothetical protein 0.0132 0.0239 0.026
Schistosoma mansoni calpain-7 (C02 family) 0.0947 0.1998 0.2167
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0017
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0094 0.0103
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0064 0.0092 0.0161
Onchocerca volvulus Deterin homolog 0.0132 0.0239 0.0452
Loa Loa (eye worm) matrixin family protein 0.0057 0.0077 0.0084
Brugia malayi Papain family cysteine protease containing protein 0.0542 0.1123 0.1221
Leishmania major receptor-type adenylate cyclase a-like protein 0.0208 0.0403 0.0694
Plasmodium vivax histone deacetylase 2, putative 0.0099 0.0167 0.0306
Loa Loa (eye worm) hypothetical protein 0.0389 0.0793 0.0861
Echinococcus multilocularis apoptotic protease activating factor 1 0.0061 0.0085 0.0085
Giardia lamblia Cathepsin L-like protease 0.0542 0.1123 0.3058
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0742 0.1555 0.1683
Echinococcus multilocularis thymidine phosphorylase 0.4655 1 1
Trichomonas vaginalis calpain, putative 0.0389 0.0793 0.1528
Leishmania major hypothetical protein, conserved 0.0208 0.0403 0.0694
Giardia lamblia Proteasome subunit beta type 1 0.0064 0.0092 0.0193
Loa Loa (eye worm) hypothetical protein 0.0024 0.0005 0.0005
Echinococcus multilocularis inhibitor of apoptosis protein 0.0132 0.0239 0.0239
Echinococcus granulosus regulator of G protein signaling 7 0.004 0.0039 0.0039
Giardia lamblia Cathepsin L precursor 0.0542 0.1123 0.3058
Brugia malayi Papain family cysteine protease containing protein 0.1306 0.2771 0.3012
Giardia lamblia Hypothetical protein 0.0251 0.0496 0.1314
Trypanosoma brucei antigen, putative 0.0944 0.1991 0.3484
Trypanosoma brucei prolyl endopeptidase 0.1651 0.3518 0.6166
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0017
Loa Loa (eye worm) hypothetical protein 0.0106 0.0182 0.0198
Toxoplasma gondii microneme protein MIC4 0.0029 0.0016 0.0014
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0019 0.0019
Loa Loa (eye worm) CYP4Cod1 0.0045 0.0051 0.0055
Schistosoma mansoni memapsin-2 (A01 family) 0.0429 0.0879 0.095
Brugia malayi PAN domain containing protein 0.0029 0.0016 0.0017
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0132 0.0239 0.026
Trypanosoma brucei GPI-anchor transamidase subunit 8 (GPI8) 0.0035 0.0028 0.0035
Echinococcus multilocularis EF hand domain containing family member A2 0.0116 0.0204 0.0204
Brugia malayi Matrixin family protein 0.0057 0.0077 0.0084
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.057 0.1183 0.2063
Brugia malayi transcriptional regulator, Sir2 family protein 0.0125 0.0222 0.0242
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2663 0.57 1
Entamoeba histolytica prolyl oligopeptidase family protein 0.0235 0.0461 0.0883
Toxoplasma gondii cathepsin B 0.17 0.3622 0.6975
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0035 0.0028 0.0054
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0132 0.0239 0.0239
Schistosoma mansoni rab 0.0116 0.0204 0.0217
Echinococcus granulosus nuclear factor of activated T cells 5 0.0075 0.0114 0.0114
Loa Loa (eye worm) sirtuin 4 0.0032 0.0023 0.0025
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.057 0.1183 0.1277
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0035 0.0028 0.0054
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0459 0.0945 0.1808
Loa Loa (eye worm) cytochrome P450 family protein 0.0058 0.0077 0.0084
Trichomonas vaginalis calmodulin, putative 0.0116 0.0204 0.0393
Onchocerca volvulus 0.0099 0.0167 0.0314
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0032 0.0032
Trypanosoma brucei histone deacetylase 2 0.0042 0.0045 0.0064
Schistosoma mansoni hypothetical protein 0.0116 0.0204 0.0217
Loa Loa (eye worm) hypothetical protein 0.0764 0.1601 0.174
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0031 0.0019 0.0019
Echinococcus granulosus histone deacetylase 6 0.0099 0.0167 0.0167
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2663 0.57 1
Trichomonas vaginalis calmodulin-2, putative 0.0116 0.0204 0.0393
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0043 0.0084
Plasmodium falciparum centrin-1 0.0116 0.0204 0.0377
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.1306 0.2771 0.3008
Giardia lamblia Cysteine protease 0.0542 0.1123 0.3058
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1209 0.2562 0.4486
Brugia malayi histone deacetylase 11 0.0042 0.0045 0.0049
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0083 0.0132 0.0216
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0764 0.1601 0.174
Echinococcus granulosus calpain A 0.2282 0.4878 0.4878
Trichomonas vaginalis calcium binding protein, putative 0.0116 0.0204 0.0393
Echinococcus multilocularis calpain A 0.2282 0.4878 0.4878
Brugia malayi histone deacetylase 3 (HD3) 0.0088 0.0143 0.0156
Trypanosoma cruzi cytochrome P450, putative 0.0045 0.0051 0.0046
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0031 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0042 0.0043 0.0047
Leishmania major calpain protease-like protein 0.0389 0.0793 0.1378
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0019 0.0016
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0939 0.198 0.2144
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0043 0.0084
Trypanosoma brucei pyruvate kinase 1, putative 0.0033 0.0024 0.0028
Trichomonas vaginalis calcium binding protein, putative 0.0124 0.0221 0.0427
Schistosoma mansoni chromatin regulatory protein sir2 0.0125 0.0222 0.0237
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0023 0.0027
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0116 0.0204 0.0343
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0031 0.0019 0.0019
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0064 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0056 0.0075 0.0082
Trypanosoma cruzi hypothetical protein, conserved 0.0235 0.0461 0.0492
Trypanosoma cruzi histone deacetylase 1, putative 0.0088 0.0143 0.0147
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.057 0.1183 0.2063
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0012 0.0013
Trypanosoma cruzi major cysteine proteinase, putative 0.0779 0.1634 0.1769
Toxoplasma gondii thioredoxin reductase 0.0048 0.0057 0.0093
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4285 0.9202 1
Brugia malayi calpain 7 0.0944 0.1991 0.2164
Brugia malayi programmed cell death protein 6 0.0116 0.0204 0.0221
Loa Loa (eye worm) cathepsin B 0.17 0.3622 0.3936
Echinococcus granulosus Regulator of G protein signaling 20 0.004 0.0039 0.0039
Brugia malayi hypothetical protein 0.004 0.0039 0.0042
Toxoplasma gondii cathepsin CPC2 0.0542 0.1123 0.2152
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1662 0.354 0.6824
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0141 0.0257 0.0279
Loa Loa (eye worm) calpain family protein 1 0.2164 0.4623 0.5024
Echinococcus granulosus EF hand domain containing family member A2 0.0116 0.0204 0.0204
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.071 0.1486 0.1607
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0208 0.0403 0.043
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0597 0.1243 0.1342
Entamoeba histolytica cysteine proteinase, putative 0.1306 0.2771 0.5339
Trypanosoma cruzi cysteine peptidase, putative 0.1306 0.2771 0.3005
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0122 0.0218 0.0232
Plasmodium vivax unspecified product 0.1306 0.2771 0.5334
Leishmania major proteasome beta 2 subunit, putative 0.004 0.0039 0.0054
Trypanosoma brucei Domain of unknown function (DUF1935), putative 0.0208 0.0403 0.0694
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0597 0.1243 0.1342
Trypanosoma cruzi oligopeptidase b 0.0698 0.1461 0.158
Loa Loa (eye worm) transcriptional regulator 0.0032 0.0023 0.0025
Loa Loa (eye worm) histone deacetylase 11 0.0042 0.0045 0.0049
Schistosoma mansoni histone deacetylase 4 5 0.0099 0.0167 0.0176
Echinococcus multilocularis calcium uptake protein 1 0.0118 0.0208 0.0208
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0264 0.0524 0.0561
Loa Loa (eye worm) prolyl oligopeptidase 0.0235 0.0461 0.0501
Brugia malayi Histone deacetylase family protein 0.0099 0.0167 0.0181
Leishmania major hypothetical protein, conserved 0.0118 0.0208 0.0351
Toxoplasma gondii cathepsin CPL 0.2426 0.5188 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0542 0.1123 0.2165
Echinococcus multilocularis FTZ F1 alpha 0.0031 0.0019 0.0019
Brugia malayi cathepsin L precursor 0.0542 0.1123 0.1221
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0125 0.0222 0.0429
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0109 0.0189 0.0173
Giardia lamblia Histone deacetylase 0.0088 0.0143 0.0336
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.004 0.0039 0.0042
Plasmodium vivax SET domain protein, putative 0.0122 0.0218 0.0404
Echinococcus multilocularis calpain 0.0944 0.1991 0.1991
Schistosoma mansoni cathepsin C 0.0542 0.1123 0.1216
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0064 0.0092 0.0161
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0208 0.0403 0.043
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0094 0.0098
Entamoeba histolytica GPI-anchor transamidase, putative 0.0035 0.0028 0.0049
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0023 0.0044
Plasmodium vivax centrin-1, putative 0.0116 0.0204 0.0377
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0898 0.1892 0.1892
Brugia malayi fibroinase precursor 0.0542 0.1123 0.1221
Echinococcus granulosus calpain 0.0944 0.1991 0.1991
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0257 0.0274
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0597 0.1243 0.2168
Trypanosoma cruzi hypothetical protein, conserved 0.0208 0.0403 0.043
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0542 0.1123 0.2152
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4285 0.9202 1
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0597 0.1243 0.1342
Echinococcus granulosus enteropeptidase 0.0037 0.0033 0.0033
Schistosoma mansoni reticulocalbin 0.0118 0.0208 0.0221
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.1651 0.3518 0.6166
Echinococcus multilocularis Glycosyl transferase, family 35 0.0105 0.0181 0.0181
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0138 0.0251 0.0484
Brugia malayi carbohydrate phosphorylase 0.0105 0.0181 0.0197
Leishmania major histone deacetylase, putative 0.0088 0.0143 0.0237
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0542 0.1123 0.2152
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Trypanosoma cruzi cysteine peptidase, putative 0.2663 0.57 0.6191
Trypanosoma brucei cysteine peptidase C (CPC) 0.17 0.3622 0.6349
Onchocerca volvulus 0.0029 0.0016 0.0021
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0016 0.0014
Trypanosoma cruzi histone deacetylase, putative 0.0099 0.0167 0.0172
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1306 0.2771 0.4854
Echinococcus granulosus glycogen phosphorylase 0.0105 0.0181 0.0181
Trichomonas vaginalis calmodulin, putative 0.0124 0.0221 0.0427
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0542 0.1123 0.1216
Trypanosoma cruzi DNA polymerase eta, putative 0.0045 0.0051 0.0046
Echinococcus granulosus neurocalcin 0.0116 0.0204 0.0204
Brugia malayi RNA binding protein 0.0065 0.0094 0.0103
Giardia lamblia Cathepsin B precursor 0.17 0.3622 1
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.004 0.0039 0.0038
Echinococcus multilocularis neuronal calcium sensor 0.0116 0.0204 0.0204
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1306 0.2771 0.5341
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0092 0.01
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0542 0.1123 0.2152
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.004 0.0039 0.0037
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Schistosoma mansoni RAR-like nuclear receptor 0.0031 0.0019 0.0016
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0389 0.0793 0.1528
Leishmania major small myristoylated protein 4, putative 0.0567 0.1177 0.2053
Brugia malayi Papain family cysteine protease containing protein 0.0542 0.1123 0.1221
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Echinococcus multilocularis enteropeptidase 0.0037 0.0033 0.0033
Schistosoma mansoni microtubule-associated protein tau 0.2086 0.4456 0.484
Leishmania major cytochrome p450-like protein 0.0045 0.0051 0.0074
Trichomonas vaginalis set domain proteins, putative 0.0972 0.2051 0.3954
Loa Loa (eye worm) RNA binding protein 0.0065 0.0094 0.0103
Echinococcus multilocularis chromatin regulatory protein sir2 0.0125 0.0222 0.0222
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0023 0.0044
Echinococcus granulosus cathepsin L cysteine proteinase 0.2426 0.5188 0.5188
Echinococcus multilocularis calmodulin 0.0116 0.0204 0.0204
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0099 0.0167 0.0182
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.071 0.1486 0.1607
Brugia malayi transcriptional regulator, Sir2 family protein 0.0032 0.0023 0.0025
Loa Loa (eye worm) cytochrome P450 family protein 0.0045 0.0051 0.0055
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0037 0.0033 0.003
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0125 0.0222 0.0222
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0043 0.0084
Entamoeba histolytica hypothetical protein 0.004 0.0039 0.0069
Giardia lamblia Cathepsin L precursor 0.0542 0.1123 0.3058
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0075 0.0114 0.0114
Leishmania major silent information regulator 2, putative 0.0125 0.0222 0.0376
Loa Loa (eye worm) hypothetical protein 0.122 0.2585 0.281
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0039 0.0037
Trypanosoma brucei proteasome subunit beta type-2, putative 0.004 0.0039 0.0054
Schistosoma mansoni hypothetical protein 0.0034 0.0026 0.0023
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0042 0.0043 0.0078
Onchocerca volvulus 0.0029 0.0016 0.0021
Loa Loa (eye worm) hypothetical protein 0.0027 0.0011 0.0012
Toxoplasma gondii kringle domain-containing protein 0.0045 0.005 0.0079
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0109 0.0189 0.0173
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0542 0.1123 0.2165
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0016 0.0017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2663 0.57 1
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2164 0.4623 0.5022
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0021
Brugia malayi ecdysteroid receptor 0.0031 0.0019 0.0021
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0776 0.1629 0.1629
Leishmania major cysteine peptidase A (CPA) 0.2426 0.5188 0.9102
Loa Loa (eye worm) hypothetical protein 0.0138 0.0251 0.0273
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0264 0.0524 0.0905
Brugia malayi prolyl oligopeptidase family protein 0.0235 0.0461 0.0501
Brugia malayi cathepsin B-like cysteine proteinase 0.4285 0.9202 1
Brugia malayi Kringle domain containing protein 0.0045 0.005 0.0054
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0125 0.0222 0.0429
Echinococcus multilocularis programmed cell death protein 0.0124 0.0221 0.0221
Trichomonas vaginalis centrin, putative 0.0116 0.0204 0.0393
Onchocerca volvulus 0.0042 0.0043 0.0075
Echinococcus multilocularis regulator of G protein signaling 7 0.004 0.0039 0.0039
Giardia lamblia Hypothetical protein 0.0542 0.1123 0.3058
Loa Loa (eye worm) hypothetical protein 0.0037 0.0033 0.0035
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.0257 0.0257
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0653 0.1363 0.238
Loa Loa (eye worm) hypothetical protein 0.0036 0.0032 0.0035
Trypanosoma brucei cysteine peptidase, putative 0.0597 0.1243 0.2168
Trichomonas vaginalis calmodulin, putative 0.0116 0.0204 0.0393
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0131 0.0236 0.0449
Loa Loa (eye worm) cysteine protease 0.2426 0.5188 0.5639
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0024 0.0026
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Entamoeba histolytica cysteine proteinase 2 0.1306 0.2771 0.5339
Trypanosoma brucei centrin, putative 0.0116 0.0204 0.0343
Leishmania major small myristoylated protein-2 0.0655 0.1368 0.2389
Echinococcus granulosus ecdysone induced protein 78C 0.0031 0.0019 0.0019
Trypanosoma cruzi cysteine proteinase, putative 0.1306 0.2771 0.3005
Plasmodium falciparum thioredoxin reductase 0.0048 0.0057 0.0093
Giardia lamblia Cathepsin L precursor 0.0542 0.1123 0.3058
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.0042 0.0043 0.0042
Loa Loa (eye worm) hypothetical protein 0.004 0.0039 0.0042
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0116 0.0204 0.0212
Onchocerca volvulus Glycogen phosphorylase homolog 0.0105 0.0181 0.034
Loa Loa (eye worm) papain family cysteine protease containing protein 0.2426 0.5188 0.5639
Schistosoma mansoni hemoglobinase (C13 family) 0.0149 0.0276 0.0295
Schistosoma mansoni hypothetical protein 0.0099 0.0167 0.0177
Brugia malayi hypothetical protein 0.0486 0.1003 0.109
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Schistosoma mansoni chromatin regulatory protein sir2 0.0138 0.0251 0.0268
Trichomonas vaginalis calcineurin B subunit, putative 0.0118 0.0208 0.0402
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0032 0.0023 0.0015
Loa Loa (eye worm) hypothetical protein 0.0045 0.0051 0.0056
Plasmodium vivax unspecified product 0.0764 0.1601 0.3075
Brugia malayi PAN domain containing protein 0.0029 0.0016 0.0017
Trypanosoma brucei proteasome beta 6 subunit 0.0064 0.0092 0.0147
Schistosoma mansoni histone deacetylase 0.0088 0.0143 0.0151
Echinococcus granulosus proteasome prosome macropain 0.0083 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.0042 0.0043 0.0047
Giardia lamblia Hypothetical protein 0.0118 0.0208 0.0516
Brugia malayi calpain family protein 1 0.2164 0.4623 0.5024
Schistosoma mansoni neuronal calcium sensor 0.0116 0.0204 0.0217
Schistosoma mansoni regulator of G protein signaling 0.004 0.0039 0.0037
Trypanosoma brucei kinesin, putative 0.0555 0.1152 0.2009
Echinococcus granulosus EF hand domain containing family member A2 0.0118 0.0208 0.0208
Mycobacterium ulcerans transglutaminase family protein 0.0251 0.0496 0.0481
Giardia lamblia Cysteine protease 0.0542 0.1123 0.3058
Echinococcus multilocularis pyruvate kinase 0.0033 0.0024 0.0024
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0389 0.0793 0.1378
Giardia lamblia Cathepsin L precursor 0.0542 0.1123 0.3058
Giardia lamblia Cysteine protease 0.0542 0.1123 0.3058
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.004 0.0039 0.0039
Loa Loa (eye worm) calpain 5 0.0555 0.1152 0.1252
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0866 0.1823 0.1823
Toxoplasma gondii prolyl endopeptidase 0.1651 0.3518 0.6775
Plasmodium falciparum serine repeat antigen 2 0.0542 0.1123 0.2152
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0021
Plasmodium vivax vivapain-2 0.2426 0.5188 1
Entamoeba histolytica prolyl oligopeptidase family protein 0.0235 0.0461 0.0883
Echinococcus multilocularis regulator of G protein signaling 0.004 0.0039 0.0039
Loa Loa (eye worm) blistered cuticle protein 3 0.0064 0.0092 0.01
Brugia malayi proteasome subunit beta type 1 0.0064 0.0092 0.01
Schistosoma mansoni hypothetical protein 0.0045 0.005 0.0049
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2663 0.57 1
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0043 0.0084
Mycobacterium ulcerans hypothetical protein 0.0037 0.0033 0.0017
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0092 0.01
Echinococcus granulosus FTZ F1 alpha 0.0031 0.0019 0.0019
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0043 0.0084
Brugia malayi prolyl oligopeptidase family protein 0.1651 0.3518 0.3823
Echinococcus multilocularis histone deacetylase 0.0099 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Brugia malayi Thioredoxin reductase 0.0048 0.0057 0.0062
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0021
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0043 0.0084
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0542 0.1123 0.2152
Trichomonas vaginalis conserved hypothetical protein 0.0116 0.0204 0.0393
Schistosoma mansoni hypothetical protein 0.0052 0.0066 0.0067
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0033 0.003
Echinococcus granulosus calumenin 0.0118 0.0208 0.0208
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0019 0.0019
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.004 0.0039 0.0038
Trypanosoma brucei hypothetical protein, conserved 0.0338 0.0682 0.1184
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0597 0.1243 0.2168
Echinococcus granulosus lamin 0.0027 0.0012 0.0012
Brugia malayi regulator of G-protein signaling egl-10 0.004 0.0039 0.0042
Onchocerca volvulus 0.0036 0.0032 0.0053
Schistosoma mansoni axis inhibition protein axin 0.004 0.0039 0.0037
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0149 0.0276 0.0532
Onchocerca volvulus Dual oxidase homolog 0.0064 0.0092 0.0169
Loa Loa (eye worm) hypothetical protein 0.0027 0.0012 0.0013
Onchocerca volvulus 0.0118 0.0208 0.0393
Brugia malayi regulator of G-protein signaling rgs-7 0.004 0.0039 0.0042
Plasmodium falciparum serine repeat antigen 5 0.0542 0.1123 0.2152
Trichomonas vaginalis calmodulin, putative 0.0118 0.0208 0.0402
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.4285 0.9202 1
Schistosoma mansoni chromatin regulatory protein sir2 0.0032 0.0023 0.002
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.0257 0.0257
Loa Loa (eye worm) hypothetical protein 0.0542 0.1123 0.1221
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0003 0.0003
Trypanosoma cruzi cruzipain precursor, putative 0.0764 0.1601 0.1733
Brugia malayi Thioredoxin family protein 0.0251 0.0496 0.0539
Trichomonas vaginalis calcium binding proteins, putative 0.0116 0.0204 0.0393
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0698 0.1461 0.2552
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0032 0.0023 0.0023
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0138 0.0251 0.0635
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0116 0.0204 0.0212
Leishmania major oligopeptidase b 0.0698 0.1461 0.2552
Onchocerca volvulus 0.0132 0.0239 0.0452
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0031 0.0019 0.0021
Mycobacterium tuberculosis Conserved protein 0.0036 0.0032 0.0016
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0019 0.0021
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0024 0.0026
Schistosoma mansoni axis inhibition protein axin 0.004 0.0039 0.0037
Trichomonas vaginalis glycogen phosphorylase, putative 0.0105 0.0181 0.0349
Echinococcus granulosus Mastin 0.0037 0.0033 0.0033
Echinococcus multilocularis peroxidasin 0.0064 0.0092 0.0092
Brugia malayi Peptidase C13 family protein 0.0149 0.0276 0.03
Echinococcus multilocularis glycogen phosphorylase 0.0105 0.0181 0.0181
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0031 0.0019 0.0019
Leishmania major sir2-family protein-like protein 0.0032 0.0023 0.0025
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0742 0.1555 0.1683
Plasmodium vivax hypothetical protein, conserved 0.0235 0.0461 0.0873
Echinococcus granulosus microtubule associated protein 2 0.2086 0.4456 0.4456
Echinococcus multilocularis lamin 0.0027 0.0012 0.0012
Giardia lamblia Cysteine protease 0.0542 0.1123 0.3058
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.2426 0.5188 1
Loa Loa (eye worm) trypsin family protein 0.0037 0.0033 0.0035
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0016 0.0017
Loa Loa (eye worm) calpain 0.0944 0.1991 0.2164
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.055 0.114 0.1231
Echinococcus granulosus pyruvate kinase 0.0033 0.0024 0.0024
Brugia malayi glutathione reductase 0.0048 0.0057 0.0062
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0019 0.0021
Brugia malayi PAN domain containing protein 0.0029 0.0016 0.0017
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0118 0.0208 0.0208
Brugia malayi Regulator of G protein signaling domain containing protein 0.004 0.0039 0.0042
Loa Loa (eye worm) MH2 domain-containing protein 0.0253 0.0499 0.0543
Leishmania major cathepsin L-like protease 0.2426 0.5188 0.9102
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0083 0.0132 0.0418
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0031 0.0019 0.0021
Trypanosoma cruzi centrin, putative 0.0124 0.0221 0.0232
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.004 0.0039 0.0076
Echinococcus multilocularis histone deacetylase 8 0.0042 0.0045 0.0045
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0125 0.0222 0.0222
Toxoplasma gondii histone deacetylase HDAC3 0.0088 0.0143 0.0261
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0094 0.0098
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2426 0.5188 1
Onchocerca volvulus 0.0037 0.0033 0.0054
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0039 0.0037
Brugia malayi Pre-SET motif family protein 0.0122 0.0218 0.0237
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.1306 0.2771 0.3005
Leishmania major proteasome beta 5 subunit, putative 0.0083 0.0132 0.0216
Brugia malayi Trypsin-like protease protein 5 0.0037 0.0033 0.0035
Schistosoma mansoni mitochondrial solute carrier 0.0116 0.0204 0.0217
Mycobacterium tuberculosis Conserved protein 0.0036 0.0032 0.0016
Plasmodium falciparum serine repeat antigen 7 0.0542 0.1123 0.2152
Trypanosoma brucei conserved protein 0.0217 0.0423 0.0728
Schistosoma mansoni peroxidasin 0.0064 0.0092 0.0095
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0542 0.1123 0.2165
Giardia lamblia Proteasome subunit beta type 2 0.004 0.0039 0.0046
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0033 0.0024 0.0009
Leishmania major hypothetical protein, conserved 0.0338 0.0682 0.1184
Echinococcus granulosus glycogen phosphorylase 0.0105 0.0181 0.0181
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0389 0.0793 0.1528
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0092 0.01
Leishmania major cathepsin L-like protease 0.2426 0.5188 0.9102
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.228 0.4874 0.4874
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0045 0.0051 0.0035
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2426 0.5188 1
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0542 0.1123 0.1221
Schistosoma mansoni calmodulin 0.0116 0.0204 0.0217
Giardia lamblia Glycogen phosphorylase 0.0105 0.0181 0.044
Onchocerca volvulus Protein ultraspiracle homolog 0.0031 0.0019 0.0029
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0235 0.0461 0.0883
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0125 0.0222 0.0423
Schistosoma mansoni cathepsin F (C01 family) 0.2426 0.5188 0.5636
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0389 0.0793 0.1528
Loa Loa (eye worm) hypothetical protein 0.0042 0.0043 0.0047
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0208 0.0403 0.043
Schistosoma mansoni hemoglobinase (C13 family) 0.0149 0.0276 0.0295
Giardia lamblia Serine peptidase, putative 0.0042 0.0043 0.0058
Loa Loa (eye worm) hypothetical protein 0.0224 0.0438 0.0475
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0019 0.0021
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0043 0.0084
Trypanosoma brucei SIR2-like protein 4, putative 0.0032 0.0023 0.0025
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.004 0.0039 0.0075
Loa Loa (eye worm) hypothetical protein 0.0542 0.1123 0.1221
Brugia malayi nuclear hormone receptor 0.0031 0.0019 0.0021
Mycobacterium tuberculosis Probable anthranilate phosphoribosyltransferase TrpD 0.1314 0.2789 0.2778
Leishmania major calmodulin, putative 0.0116 0.0204 0.0343
Onchocerca volvulus 0.0031 0.0019 0.0029
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0042 0.0043 0.0078
Trypanosoma cruzi cysteine peptidase, putative 0.0764 0.1601 0.1733
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0037 0.0033 0.003
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0235 0.0461 0.0873
Schistosoma mansoni peroxidasin 0.0064 0.0092 0.0095
Schistosoma mansoni cathepsin s 0.0764 0.1601 0.1736
Giardia lamblia Cathepsin B precursor 0.17 0.3622 1
Echinococcus granulosus calbindin 32 0.0118 0.0208 0.0208
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0042 0.0043 0.0038
Trypanosoma cruzi histone deacetylase, putative 0.0099 0.0167 0.0172
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0542 0.1123 0.2165
Loa Loa (eye worm) cytochrome P450 family protein 0.0045 0.0051 0.0055
Schistosoma mansoni neuronal calcium sensor 0.0116 0.0204 0.0217
Toxoplasma gondii troponin c, isotype gamma, putative 0.0116 0.0204 0.0377
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0032 0.0035
Brugia malayi Protein kinase domain containing protein 0.0045 0.005 0.0054
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Onchocerca volvulus 0.1662 0.354 0.6821
Brugia malayi ImpB/MucB/SamB family protein 0.0045 0.0051 0.0056
Loa Loa (eye worm) hypothetical protein 0.0542 0.1123 0.1221
Echinococcus multilocularis axis inhibition protein axin 0.004 0.0039 0.0039
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0032 0.0016
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0032 0.0023 0.0025
Loa Loa (eye worm) hypothetical protein 0.005 0.0062 0.0068
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0037 0.0033 0.0033
Schistosoma mansoni survival motor neuron protein 0.0099 0.0167 0.0177
Schistosoma mansoni chromatin regulatory protein sir2 0.0032 0.0023 0.002
Echinococcus multilocularis histone deacetylase 6 0.0105 0.018 0.018
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0031 0.0019 0.0021
Loa Loa (eye worm) transcriptional regulator 0.0032 0.0023 0.0025
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0017
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0542 0.1123 0.2152
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0264 0.0524 0.0905
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0305 0.0611 0.1059
Giardia lamblia Cathepsin B precursor 0.0542 0.1123 0.3058
Trypanosoma brucei cytochrome P450, putative 0.0045 0.0051 0.0074
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1209 0.2562 0.2777
Loa Loa (eye worm) beta-lactamase 0.0036 0.0032 0.0035
Loa Loa (eye worm) fibroinase 0.2426 0.5188 0.5639
Loa Loa (eye worm) hypothetical protein 0.4285 0.9202 1
Toxoplasma gondii EF hand domain-containing protein 0.0116 0.0204 0.0377
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0037 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.004 0.0039 0.0042
Brugia malayi Cathepsin L-like precursor 0.2426 0.5188 0.5639
Plasmodium vivax glutathione reductase, putative 0.0048 0.0057 0.0093
Onchocerca volvulus 0.0029 0.0016 0.0021
Schistosoma mansoni regulator of G protein signaling 0.004 0.0039 0.0037
Entamoeba histolytica calmodulin, putative 0.0116 0.0204 0.0387
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0122 0.0218 0.0232
Loa Loa (eye worm) hypothetical protein 0.0116 0.0204 0.0221
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0542 0.1123 0.2152
Brugia malayi Cytochrome P450 family protein 0.0058 0.0077 0.0084
Echinococcus multilocularis programmed cell death protein 0.0124 0.0221 0.0221
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0542 0.1123 0.2165
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0031 0.0019 0.0019
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0127 0.0228 0.0228
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0019 0.0021
Trypanosoma brucei hypothetical protein, conserved 0.0116 0.0204 0.0343
Brugia malayi Serine protease Z688.6 precursor 0.0042 0.0043 0.0047
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0944 0.1991 0.3484
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Loa Loa (eye worm) hypothetical protein 0.004 0.0039 0.0042
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.17 0.3622 0.3933
Toxoplasma gondii cathepsin CPC1 0.0542 0.1123 0.2152
Trypanosoma brucei calmodulin, putative 0.0116 0.0204 0.0343
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2663 0.57 1
Echinococcus multilocularis transmembrane protease serine 3 0.0037 0.0033 0.0033
Trichomonas vaginalis calmodulin, putative 0.0116 0.0204 0.0393
Leishmania major centrin, putative 0.0116 0.0204 0.0343
Trypanosoma brucei small myristoylated protein 1-1 0.036 0.073 0.1267
Onchocerca volvulus Peroxidase homolog 0.0064 0.0092 0.0169
Trypanosoma cruzi hypothetical protein, conserved 0.0045 0.005 0.0045
Schistosoma mansoni intermediate filament proteins 0.0027 0.0012 0.0008
Onchocerca volvulus 0.2426 0.5188 1
Toxoplasma gondii hypothetical protein 0.0389 0.0793 0.1514
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0542 0.1123 0.3058
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0836 0.1757 0.3073
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0032 0.0023 0.0015
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0118 0.0208 0.0217
Trypanosoma cruzi hypothetical protein, conserved 0.0338 0.0682 0.0733
Trypanosoma cruzi unspecified product 0.036 0.073 0.0784
Echinococcus multilocularis ecdysone induced protein 78C 0.0031 0.0019 0.0019
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.0024 0.0026
Trypanosoma cruzi prolyl endopeptidase 0.1651 0.3518 0.3817
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0032 0.0016
Entamoeba histolytica cysteine protease, putative 0.2426 0.5188 1
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0057 0.0052
Trypanosoma cruzi hypothetical protein, conserved 0.0208 0.0403 0.043
Toxoplasma gondii calmodulin CAM1 0.0118 0.0208 0.0386
Echinococcus multilocularis calpain 5 0.0944 0.1991 0.1991
Leishmania major small myristoylated protein-3, putative 0.0305 0.0611 0.1059
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0542 0.1123 0.1221
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0389 0.0793 0.1514
Echinococcus granulosus cathepsin b 0.4285 0.9202 0.9202
Trichomonas vaginalis calmodulin, putative 0.0116 0.0204 0.0393
Trichomonas vaginalis calcium binding protein, putative 0.0116 0.0204 0.0393
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0116 0.0204 0.0204
Onchocerca volvulus 0.2426 0.5188 1
Leishmania major DNA polymerase eta, putative 0.0045 0.0051 0.0075
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0037 0.0033 0.003
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0698 0.1461 0.521
Trichomonas vaginalis esterase, putative 0.0036 0.0032 0.0062
Brugia malayi MH2 domain containing protein 0.0253 0.0499 0.0543
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.004 0.0039 0.0042
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0122 0.0218 0.0218
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0031 0.0019 0.0016
Leishmania major centrin, putative,caltractin, putative 0.0116 0.0204 0.0343
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.004 0.0039 0.0042
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0944 0.1991 0.2157
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2663 0.57 1
Trypanosoma cruzi histone deacetylase 1, putative 0.0088 0.0143 0.0147
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0032 0.0062
Plasmodium falciparum transcriptional regulatory protein sir2b 0.0032 0.0023 0.0027
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0121 0.0215 0.02
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1662 0.354 0.6824
Loa Loa (eye worm) hypothetical protein 0.0042 0.0045 0.0049
Loa Loa (eye worm) hypothetical protein 0.0542 0.1123 0.1221
Brugia malayi Histone deacetylase family protein 0.0099 0.0167 0.0181
Toxoplasma gondii histone deacetylase HDAC5 0.0043 0.0046 0.0072
Echinococcus granulosus cathepsin l1 0.2426 0.5188 0.5188
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0597 0.1243 0.1342
Echinococcus granulosus acylamino acid releasing enzyme 0.0235 0.0461 0.0461
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0143 0.0277
Echinococcus multilocularis cathepsin l cysteine peptidase 0.2426 0.5188 0.5188
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1209 0.2562 0.2777
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0138 0.0251 0.0484
Toxoplasma gondii histone deacetylase SIR2 0.0032 0.0023 0.0027
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0019 0.0021
Entamoeba histolytica prolyl oligopeptidase family protein 0.0235 0.0461 0.0883
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0235 0.0461 0.0888
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0579 0.1204 0.21
Echinococcus granulosus chromatin regulatory protein sir2 0.0125 0.0222 0.0222
Schistosoma mansoni hypothetical protein 0.0115 0.0201 0.0214
Schistosoma mansoni hypothetical protein 0.0509 0.1053 0.1139
Brugia malayi calpain D 0.0389 0.0793 0.0861
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0698 0.1461 0.1447
Echinococcus granulosus Dipeptidyl peptidase 9 0.057 0.1183 0.1183
Brugia malayi PAN domain containing protein 0.0029 0.0016 0.0017
Plasmodium falciparum serine repeat antigen 8 0.0542 0.1123 0.2152
Onchocerca volvulus Cathepsin L homolog 0.0542 0.1123 0.2158
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0109 0.0189 0.0173
Giardia lamblia Cathepsin B precursor 0.0542 0.1123 0.3058
Trypanosoma cruzi cysteine peptidase, Clan CD, family C13, putative 0.0035 0.0028 0.0022
Leishmania major phospholipase c-like protein 0.0116 0.0204 0.0343
Echinococcus multilocularis cathepsin L cysteine protease 0.2426 0.5188 0.5188
Plasmodium falciparum serine repeat antigen 9 0.0542 0.1123 0.2152
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0016 0.0017
Plasmodium falciparum peptidase, putative 0.0235 0.0461 0.0873
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0042 0.0043 0.0068
Loa Loa (eye worm) hypothetical protein 0.0033 0.0024 0.0026
Trypanosoma brucei I/6 autoantigen 0.0116 0.0204 0.0343
Onchocerca volvulus Legumain homolog 0.0149 0.0276 0.0524
Loa Loa (eye worm) hypothetical protein 0.0235 0.0461 0.0501
Entamoeba histolytica cysteine proteinase, putative 0.1306 0.2771 0.5339
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0032 0.0016
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0094 0.0098
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0208 0.0403 0.0694
Mycobacterium ulcerans hypothetical protein 0.0251 0.0496 0.0481
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0031 0.0019 0.0021
Plasmodium falciparum GPI-anchor transamidase, putative 0.0035 0.0028 0.0038
Mycobacterium tuberculosis Conserved hypothetical protein 0.0251 0.0496 0.0481
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2663 0.57 1
Brugia malayi Trypsin family protein 0.0037 0.0033 0.0035
Trypanosoma cruzi kinesin, putative 0.0555 0.1152 0.1244
Mycobacterium tuberculosis Probable dehydrogenase 0.0109 0.0189 0.0173
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0125 0.0222 0.0233
Trichomonas vaginalis conserved hypothetical protein 0.0116 0.0204 0.0393
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0031 0.0019 0.0021
Toxoplasma gondii hypothetical protein 0.0029 0.0016 0.0014
Schistosoma mansoni Mername-AA248 (C02 family) 0.0944 0.1991 0.216
Plasmodium vivax vivapain-1 0.1306 0.2771 0.5334
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0264 0.0524 0.0905
Onchocerca volvulus 0.0542 0.1123 0.2158
Echinococcus multilocularis histone deacetylase 6 0.0099 0.0167 0.0167
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0032 0.0041
Trypanosoma brucei mitochondrial calcium uptake 1 0.0116 0.0204 0.0343
Echinococcus multilocularis pyruvate kinase 0.0033 0.0024 0.0024
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0031 0.0019 0.0021
Loa Loa (eye worm) hypothetical protein 0.1662 0.354 0.3847
Onchocerca volvulus 0.0064 0.0092 0.0169
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0944 0.1991 0.2157
Schistosoma mansoni thyroid hormone receptor 0.0158 0.0294 0.0315
Echinococcus multilocularis caspase 2 0.0061 0.0085 0.0085
Schistosoma mansoni inhibitor of apoptosis protein 0.0132 0.0239 0.0255
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0542 0.1123 0.2165
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0092 0.01
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0149 0.0276 0.0532
Echinococcus granulosus histone deacetylase 6 0.0105 0.018 0.018
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0031 0.0019 0.0021
Schistosoma mansoni calmodulin 0.0116 0.0204 0.0217
Schistosoma mansoni reticulocalbin 0.0116 0.0204 0.0217
Brugia malayi Blistered cuticle protein 3 0.0064 0.0092 0.01
Loa Loa (eye worm) hypothetical protein 0.0027 0.0012 0.0013
Plasmodium vivax serine-repeat antigen (SERA) 0.0542 0.1123 0.2152
Onchocerca volvulus 0.2426 0.5188 1
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0043 0.0084
Trypanosoma brucei oligopeptidase b 0.0698 0.1461 0.2552
Onchocerca volvulus 0.0027 0.0012 0.0015
Schistosoma mansoni regulator of G protein signaling 0.004 0.0039 0.0037
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0032 0.0016
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0064 0.0092 0.0095
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0042 0.0043 0.0043
Onchocerca volvulus 0.0029 0.0016 0.0021
Leishmania major calcineurin B subunit, putative 0.0116 0.0204 0.0343
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0116 0.0204 0.0377
Trichomonas vaginalis calmodulin, putative 0.0116 0.0204 0.0393
Giardia lamblia Cathepsin B precursor 0.0542 0.1123 0.3058
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0121 0.0215 0.0719
Mycobacterium tuberculosis Probable thymidine phosphorylase DeoA (tdrpase) (pyrimidine phosphorylase) 0.4655 1 1
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0116 0.0204 0.0387
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0031 0.0019 0.0021
Echinococcus granulosus calmodulin 0.0116 0.0204 0.0204
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0132 0.0239 0.0255
Echinococcus multilocularis microtubule associated protein 2 0.2086 0.4456 0.4456
Echinococcus granulosus prolyl endopeptidase 0.1651 0.3518 0.3518
Leishmania major programmed cell death 6 protein-like protein 0.0116 0.0204 0.0343
Echinococcus granulosus geminin 0.0509 0.1053 0.1053
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Leishmania major calmodulin, putative 0.0116 0.0204 0.0343
Brugia malayi Cathepsin L-like precursor 0.2426 0.5188 0.5639
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0305 0.0611 0.0655
Leishmania major hypothetical protein, unknown function 0.0389 0.0793 0.1378
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0597 0.1243 0.1342
Echinococcus multilocularis cathepsin L cysteine protease 0.2426 0.5188 0.5188
Onchocerca volvulus 0.0036 0.0032 0.0053
Mycobacterium leprae Probable anthranilate phosphoribosyltransferase TrpD 0.1314 0.2789 1
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0083 0.0132 0.0143
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0021
Echinococcus multilocularis acylamino acid releasing enzyme 0.0235 0.0461 0.0461
Onchocerca volvulus 0.0029 0.0016 0.0021
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0208 0.0403 0.0694
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0216 0.02
Loa Loa (eye worm) hypothetical protein 0.0037 0.0033 0.0035
Schistosoma mansoni hypothetical protein 0.0389 0.0793 0.0857
Schistosoma mansoni hypothetical protein 0.0127 0.0228 0.0243
Echinococcus multilocularis survival motor neuron protein 1 0.0486 0.1003 0.1003
Brugia malayi Matrixin family protein 0.0024 0.0005 0.0005
Brugia malayi prolyl oligopeptidase family protein 0.0811 0.1705 0.1853
Entamoeba histolytica cysteine proteinase 1, putative 0.1306 0.2771 0.5339
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0542 0.1123 0.3058
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0143 0.0277
Echinococcus granulosus cathepsin L 0.0542 0.1123 0.1123
Brugia malayi cathepsin L-like cysteine proteinase 0.0542 0.1123 0.1221
Plasmodium falciparum calpain 0.0389 0.0793 0.1514
Mycobacterium ulcerans proteasome PrcB 0.0083 0.0132 0.0116
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0264 0.0524 0.0905
Loa Loa (eye worm) EF hand family protein 0.0116 0.0204 0.0221
Giardia lamblia GPI-anchor transamidase, putative 0.0035 0.0028 0.0016
Mycobacterium ulcerans anthranilate phosphoribosyltransferase 0.1314 0.2789 0.2778
Brugia malayi Trypsin family protein 0.0037 0.0033 0.0035
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1651 0.3518 0.382
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0016 0.0017
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0542 0.1123 0.2165
Giardia lamblia Cathepsin B precursor 0.17 0.3622 1
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0032 0.0016
Schistosoma mansoni cathepsin F (C01 family) 0.1662 0.354 0.3844
Toxoplasma gondii calcium-dependent protein kinase 0.0118 0.0208 0.0386
Schistosoma mansoni pyruvate kinase 0.0033 0.0024 0.0021
Onchocerca volvulus Cell death protein 3 homolog 0.0061 0.0085 0.0154
Entamoeba histolytica calcium binding family protein 0.0116 0.0204 0.0387
Echinococcus granulosus regulator of G protein signaling 7 0.004 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0542 0.1123 0.1221
Brugia malayi hypothetical protein 0.004 0.0039 0.0042
Brugia malayi Trypsin family protein 0.0037 0.0033 0.0035
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0216 0.023
Trypanosoma cruzi histone deacetylase, putative 0.0042 0.0045 0.004
Echinococcus multilocularis Dipeptidyl peptidase 9 0.057 0.1183 0.1183
Schistosoma mansoni neuronal calcium sensor 0.0116 0.0204 0.0217
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0021
Trypanosoma cruzi calmodulin, putative 0.0116 0.0204 0.0212
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.228 0.4874 0.4874
Trypanosoma cruzi cysteine peptidase, putative 0.2426 0.5188 0.5634
Entamoeba histolytica hypothetical protein, conserved 0.0235 0.0461 0.0883
Brugia malayi Matrixin family protein 0.0024 0.0005 0.0005
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.17 0.3622 0.393
Trypanosoma brucei calpain-like protein, putative 0.0944 0.1991 0.3484
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.2426 0.5188 0.5639
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0021
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0542 0.1123 0.2152
Loa Loa (eye worm) PXA domain-containing protein 0.004 0.0039 0.0042
Schistosoma mansoni ef hand domain family member A2 0.0116 0.0204 0.0217
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0033 0.003
Loa Loa (eye worm) calmodulin-like protein 0.0116 0.0204 0.0221
Plasmodium falciparum serine repeat antigen 3 0.0542 0.1123 0.2152
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.057 0.1183 0.2063
Toxoplasma gondii histone deacetylase HDAC2 0.0088 0.0143 0.0261
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0542 0.1123 0.2161
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0037 0.0033 0.003
Brugia malayi PXA domain containing protein 0.004 0.0039 0.0042
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0029 0.0016 0.0017
Echinococcus granulosus histone deacetylase 0.0099 0.0167 0.0167
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0122 0.0216 0.02
Loa Loa (eye worm) proteasome subunit beta type 1 0.0064 0.0092 0.01
Giardia lamblia Cathepsin L precursor 0.0542 0.1123 0.3058
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0389 0.0793 0.1528
Loa Loa (eye worm) calpain D 0.0389 0.0793 0.0861
Onchocerca volvulus 0.0029 0.0016 0.0021
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0019 0.0019
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0024 0.0047
Echinococcus multilocularis Regulator of G protein signaling 20 0.004 0.0039 0.0039
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0109 0.0189 0.0625
Toxoplasma gondii EFHC1, putative 0.0116 0.0204 0.0377
Loa Loa (eye worm) hypothetical protein 0.1651 0.3518 0.3823
Plasmodium vivax histone deacetylase, putative 0.0042 0.0045 0.0071
Chlamydia trachomatis glycogen phosphorylase 0.0105 0.0181 1
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0039 0.0037
Leishmania major META domain containing protein 0.0208 0.0403 0.0694
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0032 0.0023 0.0025
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0019 0.0021
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0305 0.0611 0.0655
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0138 0.0251 0.0251
Echinococcus multilocularis histone deacetylase 6 0.0099 0.0167 0.0167
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0031 0.0019 0.0016
Plasmodium vivax proteasome subunit beta type-2, putative 0.004 0.0039 0.0059
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0122 0.0218 0.0232
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0116 0.0204 0.0212
Schistosoma mansoni histone deacetylase hda2 0.0105 0.018 0.0191
Plasmodium falciparum proteasome subunit beta type-5 0.0083 0.0132 0.0238
Echinococcus multilocularis centrin 2 0.0116 0.0204 0.0204
Mycobacterium tuberculosis Conserved protein 0.0036 0.0032 0.0016
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0083 0.0132 0.0134
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0092 0.01
Entamoeba histolytica glycogen phosphorylase, putative 0.0046 0.0052 0.0094
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0542 0.1123 0.2165
Trypanosoma cruzi major cysteine proteinase, putative 0.0542 0.1123 0.1213
Loa Loa (eye worm) hypothetical protein 0.0132 0.0239 0.026
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0031 0.0019 0.0019
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0698 0.1461 0.1447
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0811 0.1705 0.1848
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0895 0.1886 0.3298
Loa Loa (eye worm) hypothetical protein 0.0037 0.0033 0.0035
Trypanosoma cruzi hypothetical protein, conserved 0.0235 0.0461 0.0492
Brugia malayi Regulator of G protein signaling domain containing protein 0.004 0.0039 0.0042
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0542 0.1123 0.1216
Brugia malayi calcium-binding protein 0.0116 0.0204 0.0221
Trypanosoma brucei histone deacetylase 3 0.0099 0.0167 0.0278
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Mycobacterium tuberculosis Probable peptidase 0.0698 0.1461 0.1447
Leishmania major kinesin, putative 0.0555 0.1152 0.2009
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0037 0.0033 0.003
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0776 0.1629 0.1629
Loa Loa (eye worm) histone deacetylase 1 0.0088 0.0143 0.0156
Mycobacterium tuberculosis Conserved protein 0.0251 0.0496 0.0481
Entamoeba histolytica calpain large subunit domain III containing protein 0.0555 0.1152 0.2216
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0811 0.1705 0.1705
Trypanosoma brucei protein I/6 0.0116 0.0204 0.0343
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0039 0.0075
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0092 0.01
Brugia malayi hypothetical protein 0.0123 0.0219 0.0238
Brugia malayi Pre-SET motif family protein 0.0854 0.1797 0.1952
Trichomonas vaginalis myosin light chain 1, putative 0.0116 0.0204 0.0393
Brugia malayi Cathepsin L-like precursor 0.2426 0.5188 0.5639
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0125 0.0222 0.0233
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.2426 0.5188 1
Onchocerca volvulus 0.2426 0.5188 1
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0062 0.0063
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2426 0.5188 1
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1416 0.301 0.2999
Echinococcus multilocularis cathepsin l cysteine peptidase 0.2426 0.5188 0.5188
Loa Loa (eye worm) hypothetical protein 0.0023 0.0003 0.0003
Trypanosoma brucei calpain-like protein, putative 0.0944 0.1991 0.3484
Echinococcus multilocularis histone deacetylase 1 0.0088 0.0143 0.0143
Echinococcus granulosus GPI anchor transamidase 0.0035 0.0028 0.0028
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.17 0.3622 0.6349
Trypanosoma brucei caltractin, putative 0.0124 0.0221 0.0374
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.17 0.3622 0.698
Entamoeba histolytica cysteine protease, putative 0.0542 0.1123 0.2161
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1135 0.2402 0.2604
Trypanosoma cruzi centrin-3 0.0124 0.0221 0.0232
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0836 0.1757 0.3073
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0083 0.0132 0.0138
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0083 0.0132 0.0116
Entamoeba histolytica calcium-binding protein, putative 0.0116 0.0204 0.0387
Onchocerca volvulus Cathepsin F homolog 0.2426 0.5188 1
Plasmodium falciparum cysteine proteinase falcipain 2b 0.2426 0.5188 1
Echinococcus multilocularis pyruvate kinase 0.0026 0.0009 0.0009
Echinococcus multilocularis cathepsin b 0.4285 0.9202 0.9202
Schistosoma mansoni hypothetical protein 0.0509 0.1053 0.1139
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0233 0.0456 0.0441
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0579 0.1204 0.13
Mycobacterium ulcerans thymidine phosphorylase 0.4655 1 1
Brugia malayi Serine carboxypeptidase S28 family protein 0.0042 0.0043 0.0047
Onchocerca volvulus 0.0972 0.2052 0.395
Plasmodium falciparum histone deacetylase 2 0.0099 0.0167 0.0306
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0024 0.0017
Trypanosoma brucei histone deacetylase, putative 0.0099 0.0167 0.0278
Onchocerca volvulus 0.0116 0.0204 0.0384
Giardia lamblia Hypothetical protein 0.0125 0.0222 0.0555
Entamoeba histolytica glycogen phosphorylase, putative 0.0105 0.0181 0.0343
Brugia malayi hypothetical protein 0.0037 0.0033 0.0035
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0141 0.0257 0.0279
Mycobacterium ulcerans NAD-dependent deacetylase 0.0032 0.0023 0.0007
Echinococcus multilocularis regulator of G protein signaling 3 0.004 0.0039 0.0039
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0032 0.0022 0.0026
Echinococcus multilocularis calpain 7 (C02 family) 0.0944 0.1991 0.1991
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0542 0.1123 0.1216
Toxoplasma gondii histone deacetylase SIR2-like 0.0032 0.0023 0.0027
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0895 0.1886 0.3298
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0122 0.0216 0.0216
Echinococcus granulosus cathepsin l1 0.1662 0.354 0.354
Echinococcus granulosus lamin dm0 0.0027 0.0012 0.0012
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0037 0.0033 0.003
Brugia malayi NAD-dependent deacetylase SIRT1 0.0138 0.0251 0.0273
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0043 0.0084
Echinococcus multilocularis Mastin 0.0037 0.0033 0.0033
Loa Loa (eye worm) TK/ROR protein kinase 0.0045 0.005 0.0054
Loa Loa (eye worm) hypothetical protein 0.1662 0.354 0.3847
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0389 0.0793 0.1528
Loa Loa (eye worm) transcriptional regulator 0.0125 0.0222 0.0242
Leishmania major hypothetical protein, conserved 0.0208 0.0403 0.0694
Loa Loa (eye worm) hypothetical protein 0.0024 0.0005 0.0005
Leishmania major hypothetical protein, conserved 0.0045 0.005 0.0072
Loa Loa (eye worm) hypothetical protein 0.0036 0.0032 0.0035
Schistosoma mansoni regulator of G protein signaling 0.004 0.0039 0.0037
Leishmania major cathepsin L-like protease 0.2663 0.57 1
Schistosoma mansoni calpain-7 (C02 family) 0.0947 0.1998 0.2167
Brugia malayi transcriptional regulator, Sir2 family protein 0.0032 0.0023 0.0025
Trypanosoma brucei histone deacetylase 1 0.0088 0.0143 0.0237
Leishmania major histone deacetylase, putative 0.0088 0.0143 0.0237
Toxoplasma gondii centrin, putative 0.0116 0.0204 0.0377
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0542 0.1123 0.2165
Echinococcus granulosus histone deacetylase 6 0.0099 0.0167 0.0167
Loa Loa (eye worm) transcription factor SMAD2 0.0253 0.0499 0.0543
Trypanosoma brucei trypanothione reductase 0.0048 0.0057 0.0085
Mycobacterium ulcerans beta-lactamase 0.0036 0.0032 0.0016
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0016 0.0014
Trypanosoma cruzi cysteine proteinase, putative 0.1306 0.2771 0.3005
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0031 0.0019 0.0016
Echinococcus granulosus histone deacetylase 7 0.0099 0.0167 0.0167
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0895 0.1886 0.3298
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0724 0.1517 0.265
Trypanosoma brucei small myristoylated protein 1-2 0.036 0.073 0.1267
Brugia malayi cathepsin F-like cysteine proteinase 0.0542 0.1123 0.1221
Loa Loa (eye worm) hypothetical protein 0.004 0.0039 0.0042
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Entamoeba histolytica glycogen phosphorylase, putative 0.0105 0.0181 0.0343
Toxoplasma gondii microneme protein MIC17B 0.0029 0.0016 0.0014
Brugia malayi cathepsin Z-like cysteine proteinase 0.0542 0.1123 0.1221
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.1306 0.2771 0.3008
Trichomonas vaginalis calcineurin B subunit, putative 0.0116 0.0204 0.0393
Brugia malayi hypothetical protein 0.0064 0.0092 0.01
Schistosoma mansoni calpain C (C02 family) 0.0944 0.1991 0.216
Toxoplasma gondii microneme protein, putative 0.0029 0.0016 0.0014
Loa Loa (eye worm) hypothetical protein 0.0037 0.0033 0.0035
Entamoeba histolytica hypothetical protein 0.004 0.0039 0.0069
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1651 0.3518 0.382
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.004 0.0039 0.0033
Mycobacterium leprae Conserved hypothetical protein 0.0251 0.0496 0.173
Echinococcus multilocularis tissue type plasminogen activator 0.0045 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.004 0.0039 0.0042
Trypanosoma brucei Calpain-like protein 1.2 0.0742 0.1555 0.2718
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0032 0.0032
Brugia malayi calpain family protein 1 0.2164 0.4623 0.5024
Loa Loa (eye worm) hypothetical protein 0.0486 0.1003 0.109
Echinococcus granulosus histone deacetylase 1 0.0088 0.0143 0.0143
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0516 0.1067 0.1151
Echinococcus granulosus Glycosyl transferase family 35 0.0105 0.0181 0.0181
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0021
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0016 0.0014
Schistosoma mansoni calmodulin related calcium binding protein 0.0116 0.0204 0.0217
Echinococcus granulosus proteasome prosome macropain subunit beta 0.004 0.0039 0.0039
Onchocerca volvulus 0.0027 0.0012 0.0015
Echinococcus granulosus calpain A 0.0944 0.1991 0.1991
Trypanosoma cruzi small myristoylated protein 1-1 0.036 0.073 0.0784
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0037 0.0033 0.0033
Plasmodium vivax hypothetical protein, conserved 0.0118 0.0208 0.0386
Leishmania major cathepsin L-like protease 0.2426 0.5188 0.9102
Toxoplasma gondii PAN/Apple domain-containing protein 0.0029 0.0016 0.0014
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0017
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0138 0.0251 0.0251
Schistosoma mansoni neuronal calcium sensor 0.0116 0.0204 0.0217
Loa Loa (eye worm) RGS-3 protein 0.004 0.0039 0.0042
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0579 0.1204 0.21
Schistosoma mansoni glycogen phosphorylase 0.0105 0.0181 0.0192
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.0042 0.0043 0.0084
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0944 0.1991 0.2157
Echinococcus granulosus calpain 7 C02 family 0.0944 0.1991 0.1991
Brugia malayi prolyl oligopeptidase family protein 0.057 0.1183 0.1285
Echinococcus multilocularis histone deacetylase 3 0.0088 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.1608 0.3425 0.3722
Leishmania major hypothetical protein, conserved 0.0208 0.0403 0.0694
Toxoplasma gondii preprocathepsin c precursor, putative 0.0542 0.1123 0.2152
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.4285 0.9202 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.0257 0.0257
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0122 0.0218 0.0232
Plasmodium vivax NAD-dependent deacetylase, putative 0.0032 0.0023 0.0027
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0057 0.0041
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0024 0.0038
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0042 0.0043 0.0038
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2426 0.5188 1
Schistosoma mansoni histone deacetylase hda2 0.0042 0.0045 0.0044
Entamoeba histolytica calpain family cysteine protease, putative 0.0389 0.0793 0.1523
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0031 0.0019 0.0021
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0031 0.0019 0.0019
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2426 0.5188 1
Brugia malayi beta-lactamase 0.0036 0.0032 0.0035
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0542 0.1123 0.2152
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0742 0.1555 0.2718
Leishmania major hypothetical protein, conserved,calpain-like cysteine peptidase, Clan CA, family C2 0.0208 0.0403 0.0694
Loa Loa (eye worm) steroid hormone receptor 0.0031 0.0019 0.0021
Giardia lamblia Cathepsin L-like protease 0.0542 0.1123 0.3058
Onchocerca volvulus 0.0251 0.0496 0.0947
Loa Loa (eye worm) hypothetical protein 0.0154 0.0286 0.031
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0016 0.0014
Trichomonas vaginalis peptide N-glycanase, putative 0.0251 0.0496 0.0955
Entamoeba histolytica hypothetical protein 0.0542 0.1123 0.2161
Trypanosoma cruzi cysteine peptidase, putative 0.2663 0.57 0.6191
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0149 0.0276 0.0532
Echinococcus granulosus calpain 5 0.0944 0.1991 0.1991
Entamoeba histolytica NAD-dependent deacetylase 1, putative 0.0032 0.0023 0.0038
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0092 0.01
Plasmodium vivax unspecified product 0.0542 0.1123 0.2152
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0017
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0033 0.003
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0024 0.0047
Leishmania major histone deacetylase, putative 0.0099 0.0167 0.0278
Leishmania major cathepsin L-like protease 0.2663 0.57 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0122 0.0218 0.0404
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0542 0.1123 0.1221
Loa Loa (eye worm) hypothetical protein 0.0031 0.0019 0.0021
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0092 0.01
Leishmania major pyruvate kinase 0.0033 0.0024 0.0028
Schistosoma mansoni steroid hormone receptor ad4bp 0.0031 0.0019 0.0016
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0083 0.0132 0.0303
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0116 0.0204 0.0204
Echinococcus multilocularis histone deacetylase 7 0.0099 0.0167 0.0167
Loa Loa (eye worm) calpain family protein 1 0.1608 0.3425 0.3722
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0032 0.0023 0.0023
Entamoeba histolytica hypothetical protein 0.004 0.0039 0.0069
Trypanosoma cruzi I/6 autoantigen, putative 0.0116 0.0204 0.0212
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0116 0.0204 0.0393
Echinococcus granulosus histone deacetylase 8 0.0042 0.0045 0.0045
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0031 0.0019 0.0021
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0042 0.0043 0.0084
Brugia malayi Histone deacetylase 1 0.0088 0.0143 0.0156
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0542 0.1123 0.2165
Schistosoma mansoni thyroid hormone receptor 0.0158 0.0294 0.0315
Echinococcus multilocularis geminin 0.0509 0.1053 0.1053
Leishmania major hypothetical protein, conserved 0.0036 0.0032 0.0041
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0939 0.198 0.3464
Brugia malayi Hemopexin family protein 0.0034 0.0026 0.0028
Plasmodium vivax vivapain-2 0.2426 0.5188 1
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0149 0.0276 0.0532
Entamoeba histolytica calmodulin, putative 0.0116 0.0204 0.0387
Giardia lamblia Pyruvate kinase 0.0033 0.0024 0.0005
Brugia malayi EF hand family protein 0.0118 0.0208 0.0226
Mycobacterium tuberculosis Transcriptional regulatory protein 0.0032 0.0023 0.0007
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0024 0.0026
Trypanosoma cruzi hypothetical protein, conserved 0.0208 0.0403 0.043
Echinococcus granulosus centrin 2 0.0116 0.0204 0.0204
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0149 0.0276 0.0532
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0542 0.1123 0.1216
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0542 0.1123 0.2165
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0116 0.0204 0.0212
Echinococcus granulosus regulator of G protein signaling 3 0.004 0.0039 0.0039
Toxoplasma gondii ABC1 family protein 0.0036 0.0032 0.0046
Onchocerca volvulus 0.0122 0.0218 0.0411
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Echinococcus multilocularis calmodulin 0.0116 0.0204 0.0204
Trypanosoma cruzi cruzipain precursor, putative 0.2663 0.57 0.6191
Brugia malayi EF hand family protein 0.0116 0.0204 0.0221
Loa Loa (eye worm) hypothetical protein 0.2426 0.5188 0.5639
Echinococcus granulosus apoptotic protease activating factor 1 0.0061 0.0085 0.0085
Leishmania major GPI-anchor transamidase subunit 8 (GPI8), putative 0.0035 0.0028 0.0035
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0542 0.1123 0.2165
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2663 0.57 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0033 0.003
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0088 0.0143 0.0277
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.1899 0.4052 0.4398
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.1209 0.2562 0.2777
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2663 0.57 1
Leishmania major protein kinase, putative 0.0116 0.0204 0.0343
Trypanosoma cruzi conserved protein 0.0606 0.1262 0.1363
Brugia malayi Cytochrome P450 family protein 0.0045 0.0051 0.0055
Toxoplasma gondii peptidase c13 family protein 0.0035 0.0028 0.0038
Plasmodium falciparum cysteine repeat modular protein 1 0.0045 0.005 0.0079
Trichomonas vaginalis centrin, putative 0.0116 0.0204 0.0393
Leishmania major hypothetical protein, conserved 0.0606 0.1262 0.2202
Brugia malayi Cathepsin L-like cysteine proteinase 0.1662 0.354 0.3847
Echinococcus granulosus tachykinin peptides receptor 99D 0.0898 0.1892 0.1892
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0094 0.0094
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0039 0.0075
Schistosoma mansoni calpain-2 (C02 family) 0.0389 0.0793 0.0857
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0024 0.0038
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0023 0.0044
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0542 0.1123 0.2165
Echinococcus multilocularis regulator of G protein signaling 7 0.004 0.0039 0.0039
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0033 0.003
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0032 0.0016
Loa Loa (eye worm) hypothetical protein 0.0542 0.1123 0.1221
Echinococcus multilocularis Transglutaminase 0.0251 0.0496 0.0496
Leishmania major cathepsin L-like protease 0.2426 0.5188 0.9102
Onchocerca volvulus 0.0036 0.0032 0.0053
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0811 0.1705 0.1705
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0305 0.0611 0.1059
Onchocerca volvulus Prolyl endopeptidase homolog 0.1651 0.3518 0.6777
Trypanosoma cruzi calmodulin, putative 0.0116 0.0204 0.0212
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0019 0.0021
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0939 0.198 0.2144
Leishmania major calmodulin-like protein 0.0116 0.0204 0.0343
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0542 0.1123 0.3058
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0086 0.014 0.014
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0057 0.0062
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0017
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0032 0.003
Brugia malayi Matrixin family protein 0.0024 0.0005 0.0005
Loa Loa (eye worm) histone deacetylase 3 0.0088 0.0143 0.0156
Echinococcus multilocularis axis inhibition protein axin 0.004 0.0039 0.0039
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0064 0.0092 0.0177
Trypanosoma cruzi calmodulin, putative 0.0116 0.0204 0.0212
Loa Loa (eye worm) hypothetical protein 0.2164 0.4623 0.5024
Brugia malayi PAN domain containing protein 0.0029 0.0016 0.0017
Entamoeba histolytica hypothetical protein, conserved 0.0118 0.0208 0.0396
Toxoplasma gondii proteasome subunit beta type 2, putative 0.004 0.0039 0.0059
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2426 0.5188 1
Echinococcus multilocularis calumenin 0.0118 0.0208 0.0208
Echinococcus multilocularis cathepsin b 0.4285 0.9202 0.9202
Schistosoma mansoni glycogen phosphorylase 0.0046 0.0052 0.0051
Onchocerca volvulus 0.0037 0.0033 0.0054
Plasmodium vivax pyruvate kinase, putative 0.0033 0.0024 0.0031
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.1306 0.2771 0.3008
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Echinococcus granulosus caspase 2 0.0061 0.0085 0.0085
Plasmodium vivax serine-repeat antigen (SERA) 0.0542 0.1123 0.2152
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0032 0.0023 0.0044
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0031 0.0019 0.0016
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0083 0.0132 0.0248
Trichomonas vaginalis calmodulin, putative 0.0116 0.0204 0.0393
Plasmodium falciparum glutathione reductase 0.0048 0.0057 0.0093
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0127 0.0228 0.0228
Echinococcus multilocularis lamin dm0 0.0027 0.0012 0.0012
Schistosoma mansoni pyruvate kinase 0.0033 0.0024 0.0021
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0542 0.1123 0.1216
Trypanosoma brucei prolyl oligopeptidase, putative 0.0698 0.1461 0.2552
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0542 0.1123 0.1216
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.0019 0.0016
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0216 0.023
Brugia malayi Papain family cysteine protease containing protein 0.0542 0.1123 0.1221
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0542 0.1123 0.1216
Plasmodium vivax histone deacetylase, putative 0.0099 0.0167 0.0306
Echinococcus multilocularis cathepsin L 0.1306 0.2771 0.2771
Entamoeba histolytica cysteine protease, putative 0.0542 0.1123 0.2161
Schistosoma mansoni hypothetical protein 0.0251 0.0496 0.0534
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0121 0.0215 0.02
Onchocerca volvulus 0.0037 0.0033 0.0054
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0116 0.0204 0.0393
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0039 0.0075
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0042 0.0043 0.0084
Loa Loa (eye worm) glutathione reductase 0.0048 0.0057 0.0062
Echinococcus granulosus inhibitor of apoptosis protein 0.0132 0.0239 0.0239
Echinococcus granulosus histone lysine methyltransferase setb 0.0122 0.0218 0.0218
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0542 0.1123 0.2152
Brugia malayi hypothetical protein 0.0224 0.0438 0.0475
Loa Loa (eye worm) hypothetical protein 0.0036 0.0032 0.0035
Trypanosoma cruzi caltractin, putative 0.0116 0.0204 0.0212
Plasmodium falciparum histone deacetylase, putative 0.0099 0.0167 0.0306
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0086 0.014 0.014
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0032 0.0023 0.0023
Toxoplasma gondii subtilisin SUB12 0.0029 0.0016 0.0014
Echinococcus multilocularis tumor protein p63 0.0344 0.0696 0.0696
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0939 0.198 0.3464
Onchocerca volvulus 0.2426 0.5188 1
Brugia malayi nuclear receptor NHR-88 0.0031 0.0019 0.0021
Loa Loa (eye worm) hypothetical protein 0.0024 0.0005 0.0005
Schistosoma mansoni cathepsin S (C01 family) 0.0542 0.1123 0.1216
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0143 0.0277
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0579 0.1204 0.21
Loa Loa (eye worm) hypothetical protein 0.0345 0.0699 0.0759
Schistosoma mansoni lamin 0.0027 0.0012 0.0008
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Onchocerca volvulus 0.0034 0.0026 0.0041
Brugia malayi Cathepsin L-like precursor 0.2426 0.5188 0.5639
Brugia malayi Cathepsin L-like precursor 0.1662 0.354 0.3847
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0597 0.1243 0.1342
Onchocerca volvulus 0.2426 0.5188 1
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0542 0.1123 0.2152
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0542 0.1123 0.3058
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2426 0.5188 1
Entamoeba histolytica cysteine protease, putative 0.0542 0.1123 0.2161
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0092 0.01
Mycobacterium leprae Probable pyruvate kinase PykA 0.0033 0.0024 0.0031
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0116 0.0204 0.0387
Trichomonas vaginalis calpain, putative 0.0389 0.0793 0.1528
Plasmodium falciparum histone deacetylase 1 0.0088 0.0143 0.0261
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0039 0.0075
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0032 0.0023 0.0023
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Trypanosoma cruzi hypothetical protein, conserved 0.0338 0.0682 0.0733
Loa Loa (eye worm) hypothetical protein 0.0036 0.0032 0.0035
Plasmodium falciparum serine repeat antigen 4 0.0542 0.1123 0.2152
Brugia malayi Cytochrome P450 family protein 0.0045 0.0051 0.0055
Trypanosoma brucei Component of motile flagella 41 0.0116 0.0204 0.0343
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.1135 0.2402 0.2604
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0083 0.0132 0.0134
Echinococcus granulosus EF HAND 1 calcium binding site 0.0116 0.0204 0.0204
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0033 0.003
Schistosoma mansoni calpain (C02 family) 0.0944 0.1991 0.216
Onchocerca volvulus 0.2426 0.5188 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0939 0.198 0.3464
Schistosoma mansoni z-protein (S1r protein) 0.004 0.0039 0.0037
Schistosoma mansoni hypothetical protein 0.0132 0.0239 0.0255
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0032 0.0016
Onchocerca volvulus Peroxidasin homolog 0.0064 0.0092 0.0169
Plasmodium vivax histone deacetylase 1, putative 0.0088 0.0143 0.0261
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0094 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.0338 0.0682 0.1315
Trypanosoma cruzi oligopeptidase b 0.0698 0.1461 0.158
Echinococcus multilocularis neurocalcin 0.0116 0.0204 0.0204
Echinococcus granulosus cathepsin L 0.1306 0.2771 0.2771
Trypanosoma cruzi cysteine peptidase, putative 0.2663 0.57 0.6191
Loa Loa (eye worm) hypothetical protein 0.0088 0.0143 0.0156
Brugia malayi Cell death protein 3 precursor 0.0061 0.0085 0.0092
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0064 0.0092 0.0091
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0542 0.1123 0.2165
Loa Loa (eye worm) ctsf protein 0.2426 0.5188 0.5639
Toxoplasma gondii proteasome subunit beta type, putative 0.0083 0.0132 0.0238
Entamoeba histolytica cysteine proteinase, putative 0.1306 0.2771 0.5339
Loa Loa (eye worm) hypothetical protein 0.0063 0.0089 0.0096
Schistosoma mansoni cathepsin F (C01 family) 0.2426 0.5188 0.5636
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-4 0.0208 0.0403 0.0694
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0035 0.0028 0.0054
Mycobacterium ulcerans pyruvate kinase 0.0033 0.0024 0.0009
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0216 0.02
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0143 0.0277
Echinococcus granulosus tar DNA binding protein 0.0065 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Entamoeba histolytica glycogenphosphorylase, putative 0.0046 0.0052 0.0094
Onchocerca volvulus Chorion peroxidase homolog 0.0064 0.0092 0.0169
Echinococcus granulosus expressed protein 0.0769 0.1614 0.1614
Trypanosoma brucei calpain-like protein, putative 0.1209 0.2562 0.4486
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0143 0.0277
Schistosoma mansoni DNA polymerase eta 0.0045 0.0051 0.0051
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0389 0.0793 0.1378
Onchocerca volvulus 0.0029 0.0016 0.0021
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0579 0.1204 0.13
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0094 0.0098
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0033 0.003
Giardia lamblia Thymus-specific serine protease precursor 0.0042 0.0043 0.0058
Leishmania major pyruvate kinase 0.0033 0.0024 0.0028
Loa Loa (eye worm) hypothetical protein 0.0764 0.1601 0.174
Echinococcus granulosus cathepsin L cysteine protease 0.1306 0.2771 0.2771
Echinococcus multilocularis dna polymerase eta 0.0045 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0122 0.0218 0.0237
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0031 0.0019 0.0029
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0043 0.0084
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0542 0.1123 0.1216
Entamoeba histolytica cysteine protease, putative 0.1306 0.2771 0.5339
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0043 0.0084
Trypanosoma cruzi histone deacetylase, putative 0.0099 0.0167 0.0172
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Trichomonas vaginalis histone deacetylase, putative 0.0088 0.0143 0.0277
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0064 0.0092 0.0092
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0031 0.0019 0.0021
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0542 0.1123 0.2152
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0032 0.0062
Loa Loa (eye worm) hypothetical protein 0.0116 0.0204 0.0221
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Trichomonas vaginalis conserved hypothetical protein 0.0235 0.0461 0.0888
Echinococcus granulosus transmembrane protease serine 3 0.0037 0.0033 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Brugia malayi PAN domain containing protein 0.0029 0.0016 0.0017
Trypanosoma cruzi DNA polymerase eta, putative 0.0032 0.0022 0.0015
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0042 0.0043 0.0078
Schistosoma mansoni centrin 0.0116 0.0204 0.0217
Mycobacterium tuberculosis Probable reductase 0.0109 0.0189 0.0173
Echinococcus granulosus cysteine protease 0.1306 0.2771 0.2771
Loa Loa (eye worm) hypothetical protein 0.0064 0.0092 0.01
Mycobacterium ulcerans hypothetical protein 0.0036 0.0032 0.0016
Echinococcus multilocularis GPI anchor transamidase 0.0035 0.0028 0.0028
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0132 0.0239 0.0239
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0109 0.0189 0.0173
Schistosoma mansoni centrin-related 0.0116 0.0204 0.0217
Echinococcus granulosus neuronal calcium sensor 0.0116 0.0204 0.0204
Trichomonas vaginalis calmodulin, putative 0.0116 0.0204 0.0393
Brugia malayi PAN domain containing protein 0.0029 0.0016 0.0017
Mycobacterium leprae Probable lipase LipE 0.0036 0.0032 0.0059
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0542 0.1123 0.2152
Echinococcus granulosus survival motor neuron protein 1 0.0486 0.1003 0.1003
Onchocerca volvulus Matrilysin homolog 0.0053 0.0067 0.012
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0033 0.003
Schistosoma mansoni lamin 0.0027 0.0012 0.0008
Entamoeba histolytica cysteine protease, putative 0.0542 0.1123 0.2161
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0032 0.0026
Loa Loa (eye worm) hypothetical protein 0.1662 0.354 0.3847
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0031 0.0019 0.0016
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.004 0.0039 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0389 0.0793 0.1528
Mycobacterium ulcerans Sir2-like regulatory protein 0.0032 0.0023 0.0007
Onchocerca volvulus Peroxidase homolog 0.0064 0.0092 0.0169
Leishmania major hypothetical protein, conserved 0.0208 0.0403 0.0694
Echinococcus granulosus peroxidasin 0.0064 0.0092 0.0092
Toxoplasma gondii PAN domain-containing protein 0.0029 0.0016 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0039 0.0075
Loa Loa (eye worm) histone deacetylase 0.0099 0.0167 0.0181
Loa Loa (eye worm) glycogen phosphorylase 0.0105 0.0181 0.0197
Entamoeba histolytica cysteine protease, putative 0.0542 0.1123 0.2161
Loa Loa (eye worm) PAN domain-containing protein 0.0029 0.0016 0.0017
Schistosoma mansoni histone deacetylase 1 2 3 0.0042 0.0045 0.0044
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1306 0.2771 0.4854
Leishmania major DNA polymerase eta, putative 0.0032 0.0022 0.0024
Trypanosoma brucei hypothetical protein 0.0653 0.1363 0.238
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0033 0.003
Echinococcus granulosus glycoprotein Antigen 5 0.0037 0.0033 0.0033
Echinococcus granulosus cathepsin l cysteine peptidase 0.2426 0.5188 0.5188
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2426 0.5188 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Brugia malayi hypothetical protein 0.0061 0.0085 0.0092
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.0257 0.0257
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.004 0.0039 0.0076
Loa Loa (eye worm) programmed cell death protein 6 0.0118 0.0208 0.0226
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0046 0.0052 0.0036
Echinococcus granulosus tumor protein p63 0.0344 0.0696 0.0696
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0042 0.0043 0.0084
Loa Loa (eye worm) hypothetical protein 0.0036 0.0032 0.0035
Echinococcus multilocularis EF hand domain containing family member A2 0.0118 0.0208 0.0208
Trypanosoma cruzi hypothetical protein, conserved 0.0208 0.0403 0.043
Onchocerca volvulus Histone deacetylase 10 homolog 0.0042 0.0045 0.0078
Onchocerca volvulus 0.0029 0.0016 0.0021
Brugia malayi photoreceptor-specific nuclear receptor 0.0031 0.0019 0.0021
Trichomonas vaginalis calpain, putative 0.0389 0.0793 0.1528
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0032 0.0062
Brugia malayi Cathepsin L-like precursor 0.1662 0.354 0.3847
Schistosoma mansoni chromatin regulatory protein sir2 0.0125 0.0222 0.0237
Trypanosoma brucei calpain-like protein, putative 0.0944 0.1991 0.3484
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0698 0.1461 0.2552
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0039 0.0075
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0149 0.0276 0.0532
Leishmania major calpain family cysteine protease-like protein 0.0597 0.1243 0.2168
Loa Loa (eye worm) hypothetical protein 0.0045 0.005 0.0054
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.1209 0.2562 0.4486
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0033 0.003
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0037 0.0033 0.0033
Trichomonas vaginalis glycogen phosphorylase, putative 0.0105 0.0181 0.0349
Echinococcus multilocularis glycoprotein Antigen 5 0.0037 0.0033 0.0033
Onchocerca volvulus 0.0037 0.0033 0.0054
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Trypanosoma brucei calpain, putative 0.0389 0.0793 0.1378
Echinococcus granulosus axis inhibition protein axin 0.004 0.0039 0.0039
Echinococcus multilocularis prolyl endopeptidase 0.1651 0.3518 0.3518
Trypanosoma cruzi 20S proteasome subunit 0.004 0.0039 0.0033
Onchocerca volvulus 0.0116 0.0204 0.0384
Schistosoma mansoni histone deacetylase 4 5 0.0099 0.0167 0.0176
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.1209 0.2562 0.4486
Plasmodium falciparum proteasome subunit beta type-2, putative 0.004 0.0039 0.0059
Brugia malayi Papain family cysteine protease containing protein 0.2426 0.5188 0.5639
Entamoeba histolytica cysteine proteinase, putative 0.2426 0.5188 1
Echinococcus multilocularis cysteine protease 0.2426 0.5188 0.5188
Trypanosoma cruzi cysteine protease, putative 0.1306 0.2771 0.3005
Schistosoma mansoni hypothetical protein 0.0037 0.0033 0.003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2426 0.5188 1
Loa Loa (eye worm) hypothetical protein 0.0061 0.0085 0.0092
Brugia malayi GPI-anchor transamidase 0.0035 0.0028 0.0031
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0542 0.1123 0.2161
Leishmania major small myristoylated protein-1 0.036 0.073 0.1267
Schistosoma mansoni regulator of G protein signaling 0.004 0.0039 0.0037
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4285 0.9202 1
Giardia lamblia Cathepsin B precursor 0.0542 0.1123 0.3058
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0764 0.1601 0.174
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0083 0.0132 0.0254
Plasmodium falciparum cysteine proteinase falcipain 2a 0.2426 0.5188 1
Onchocerca volvulus 0.0037 0.0033 0.0054
Leishmania major trypanothione reductase 0.0048 0.0057 0.0085
Plasmodium vivax proteasome subunit beta type-5, putative 0.0083 0.0132 0.0238
Leishmania major hypothetical protein, conserved 0.0208 0.0403 0.0694
Plasmodium vivax vivapain-3 0.1306 0.2771 0.5334
Schistosoma mansoni family C13 non-peptidase homologue (C13 family) 0.0149 0.0276 0.0295
Toxoplasma gondii microneme protein MIC17C 0.0029 0.0016 0.0014
Trypanosoma brucei centrin, putative 0.0116 0.0204 0.0343
Echinococcus granulosus histone deacetylase 3 0.0088 0.0143 0.0143
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0012 0.0013
Trypanosoma cruzi small myristoylated protein 1-2 0.036 0.073 0.0784
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2663 0.57 1
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0032 0.0023 0.0038
Loa Loa (eye worm) hypothetical protein 0.0037 0.0033 0.0035
Trypanosoma brucei Calpain-like protein 1.1 0.0939 0.198 0.3464
Plasmodium vivax calpain, putative 0.0944 0.1991 0.3828
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0264 0.0524 0.0905
Schistosoma mansoni cercarial elastase (S01 family) 0.0037 0.0033 0.003
Entamoeba histolytica cysteine proteinase, putative 0.2426 0.5188 1
Mycobacterium ulcerans hypothetical protein 0.0251 0.0496 0.0481
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0032 0.0062
Loa Loa (eye worm) hypothetical protein 0.0061 0.0085 0.0092
Plasmodium vivax proteasome subunit beta type-1, putative 0.0064 0.0092 0.0161
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.004 0.0039 0.0037
Brugia malayi cathepsin F-like cysteine proteinase 0.0764 0.1601 0.174
Brugia malayi cathepsin L-like precursor 0.1662 0.354 0.3847
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0257 0.0274
Mycobacterium ulcerans putative transglutaminase-like protein 0.0251 0.0496 0.0481
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0032 0.0046
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0094 0.0103
Plasmodium falciparum cysteine proteinase falcipain 1 0.1306 0.2771 0.5334
Leishmania major calmodulin-like protein 0.0116 0.0204 0.0343
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.004 0.0039 0.0037
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2426 0.5188 1
Giardia lamblia Hypothetical protein 0.0542 0.1123 0.3058
Entamoeba histolytica cysteine proteinase, putative 0.1306 0.2771 0.5339
Onchocerca volvulus 0.122 0.2585 0.4979
Brugia malayi histone deacetylase 1 (HD1) 0.0088 0.0143 0.0156
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0032 0.003
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0698 0.1461 0.158
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0138 0.0251 0.0484
Brugia malayi proteasome subunit beta type 2 0.004 0.0039 0.0043
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0542 0.1123 0.2165
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0542 0.1123 0.2165
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0064 0.0092 0.0172
Onchocerca volvulus Cathepsin L homolog 0.2426 0.5188 1
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0064 0.0092 0.0091
Loa Loa (eye worm) histone deacetylase 7A 0.0099 0.0167 0.0181
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0031 0.0019 0.0021
Brugia malayi TAR-binding protein 0.0065 0.0094 0.0103
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.057 0.1183 0.1281
Brugia malayi PAN domain containing protein 0.0029 0.0016 0.0017
Brugia malayi prolyl oligopeptidase family protein 0.0235 0.0461 0.0501
Mycobacterium tuberculosis Conserved hypothetical protein 0.0251 0.0496 0.0481
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0031 0.0019 0.0019

Activities

Activity type Activity value Assay description Source Reference
CC50 (functional) > 56.4 uM Concentration of the compound required to reduce the viability of uninfected MT-4 cells by 50% ChEMBL. 9022801
IC50 (functional) 0 uM Concentration of the compound required to reduce herpes simplex virus-1TK (F) inducted cytopathicity by 50% (E6SM cells); Not determined ChEMBL. 9022801
IC50 (functional) 0 uM Concentration of the compound required to reduce herpes simplex virus-1TK (McIntyre) inducted cytopathicity by 50% (E6SM cells); Not determined ChEMBL. 9022801
IC50 (functional) 0 uM Concentration of the compound required to reduce herpes simplex virus-2(196) inducted cytopathicity by 50% (E6SM cells); Not determined ChEMBL. 9022801
IC50 (functional) 0 uM Concentration of the compound required to reduce herpes simplex virus-2(Lyons) inducted cytopathicity by 50% (E6SM cells); Not determined ChEMBL. 9022801
IC50 (functional) 0 uM Concentration of the compound required to reduce forest virus-inducted cytopathicity by 50% (Vero cells); Not determined ChEMBL. 9022801
IC50 (functional) 0 uM Concentration of the compound required to reduce polio-1 virus-inducted cytopathicity by 50% (HeLa cells); Not determined ChEMBL. 9022801
IC50 (functional) = 0.04 uM Concentration of the compound required to inhibit human immunodeficiency virus-1 induced cytopathicity in MT-4 cells by 50% ChEMBL. 9022801
IC50 (functional) = 0.37 uM Concentration of the compound required to inhibit human immunodeficiency virus-1 induced cytopathicity in MT-4 cells by 50% ChEMBL. 9022801
IC50 (functional) = 0.4 uM Concentration of the compound required to reduce human cytomegalo virus(Davis) inducted cytopathicity by 50% (HEL cells) ChEMBL. 9022801
IC50 (functional) = 1.4 uM Concentration of the compound required to reduce human cytomegalo virus(AD-169) inducted cytopathicity by 50% (HEL cells) ChEMBL. 9022801
IC50 (functional) = 1.8 uM Concentration required to inhibit by 50% human immunodeficiency virus-1 induced syncytium formation upon coculturing persistently HIV-infected HUT-78 cells with MOLT-4 cells ChEMBL. 9022801
IC50 (functional) = 3.6 uM Concentration of the compound required to reduce human cytomegalo virus(Davis) inducted cytopathicity by 50% (HEL cells) ChEMBL. 9022801
IC50 (functional) = 3.61 uM Concentration required to inhibit by 50% human immunodeficiency virus-1 induced syncytium formation upon coculturing persistently HIV-infected HUT-78 cells with MOLT-4 cells ChEMBL. 9022801
IC50 (functional) = 4.17 uM Concentration of the compound required to inhibit human immunodeficiency virus-2 induced cytopathicity in MT-4 cells by 50% ChEMBL. 9022801
IC50 (functional) = 4.47 uM Concentration of the compound required to inhibit human immunodeficiency virus-2 induced cytopathicity in MT-4 cells by 50% ChEMBL. 9022801
IC50 (functional) = 6.3 uM Concentration of the compound required to reduce human cytomegalo virus(AD-169) inducted cytopathicity by 50% (HEL cells) ChEMBL. 9022801
IC50 (functional) > 22 uM Concentration of the compound required to reduce Junin virus-inducted cytopathicity by 50% (Vero cells) ChEMBL. 9022801
IC50 (functional) > 22 uM Concentration of the compound required to reduce Tacaribe virus-inducted cytopathicity by 50% (Vero cells) ChEMBL. 9022801
IC50 (functional) > 22 uM Concentration of the compound required to inhibit HEL cell growth by 50% ChEMBL. 9022801
IC50 (functional) = 45 uM Concentration of the compound required to reduce herpes simplex virus-1TK( B2006) inducted cytopathicity by 50% (E6SM cells) ChEMBL. 9022801
IC50 (functional) > 45 uM Concentration of the compound required to reduce herpes simplex virus-2(G) inducted cytopathicity by 50% (E6SM cells) ChEMBL. 9022801
IC50 (functional) = 54.2 uM Concentration of the compound required to inhibit by 50% human immunodeficiency virus-2 induced syncytium formation upon coculturing persistently HIV-infected HUT-78 cells with MOLT-4 cells ChEMBL. 9022801
IC50 (functional) = 68 uM Concentration of the compound required to reduce herpes simplex virus-1TK( B2006) inducted cytopathicity by 50% (E6SM cells) ChEMBL. 9022801
IC50 (functional) = 136 uM Concentration of the compound required to reduce herpes simplex virus-1TK (KOS) inducted cytopathicity by 50% (E6SM cells) ChEMBL. 9022801
IC50 (functional) = 136 uM Concentration of the compound required to reduce herpes simplex virus-2(G) inducted cytopathicity by 50% (E6SM cells) ChEMBL. 9022801
IC50 (functional) > 181 uM Concentration of the compound required to reduce herpes simplex virus-1TK (VMW1837) inducted cytopathicity by 50% (E6SM cells) ChEMBL. 9022801
IC50 (functional) > 181 uM Concentration of the compound required to reduce herpes simplex virus-1TK (KOS) inducted cytopathicity by 50% (E6SM cells) ChEMBL. 9022801
IC50 (functional) > 181 uM Concentration required to reduce vaccinia virus-inducted cytopathicity by 50% (E6SM cells) ChEMBL. 9022801
IC50 (functional) > 181 uM Concentration of the compound required to reduce vesicular stomatitis virus-inducted cytopathicity by 50% (HeLa cells) ChEMBL. 9022801
IC50 (functional) > 181 uM Concentration of the compound required to reduce parainfuenza-3 virus-inducted cytopathicity by 50% (Vero cells) ChEMBL. 9022801
IC50 (functional) > 181 uM Concentration of the compound required to reduce reovirus-1 inducted cytopathicity by 50% (Vero cells) ChEMBL. 9022801
IC50 (functional) > 181 uM Concentration of the compound required to reduce sindbis virus-inducted cytopathicity by 50% (Vero cells) ChEMBL. 9022801
IC50 (functional) > 181 uM Concentration of the compound required to reduce Coxsackie virus-inducted cytopathicity by 50% (Vero cells) ChEMBL. 9022801
IC50 (functional) > 181 uM Concentration of the compound required to reduce Coxsackie virus-inducted cytopathicity by 50% (HeLa cells) ChEMBL. 9022801
IC50 (functional) > 181 uM Concentration of the compound required to cause a microscopically detectable alteration of normal E6SM cell morphology ChEMBL. 9022801
IC50 (functional) > 181 uM Concentration of the compound required to cause a microscopically detectable alteration of normal Hela cell morphology ChEMBL. 9022801
IC50 (functional) > 181 uM Concentration of the compound required to cause a microscopically detectable alteration of normal Vero cell morphology ChEMBL. 9022801

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.