Detailed information for compound 424475

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 244.675 | Formula: C10H13ClN2O3
  • H donors: 3 H acceptors: 2 LogP: 1.22 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: ONC(=O)C(NOCc1ccc(cc1)Cl)C
  • InChi: 1S/C10H13ClN2O3/c1-7(10(14)12-15)13-16-6-8-2-4-9(11)5-3-8/h2-5,7,13,15H,6H2,1H3,(H,12,14)
  • InChiKey: JNDVWCINXNIDOF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens carbonic anhydrase I Starlite/ChEMBL References
Homo sapiens carbonic anhydrase II Starlite/ChEMBL References
Homo sapiens carbonic anhydrase IX Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) carbonic anhydrase 3 Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania braziliensis carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania major carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma brucei gambiense carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma cruzi carbonic anhydrase-like protein, putative Get druggable targets OG5_127628 All targets in OG5_127628
Schistosoma japonicum ko:K01672 carbonic anhydrase [EC4.2.1.1], putative Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania infantum carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Brugia malayi Eukaryotic-type carbonic anhydrase family protein Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma congolense carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Echinococcus multilocularis carbonic anhydrase II Get druggable targets OG5_127628 All targets in OG5_127628
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma brucei carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Brugia malayi Putative carbonic anhydrase 5 precursor Get druggable targets OG5_127628 All targets in OG5_127628
Echinococcus granulosus carbonic anhydrase II Get druggable targets OG5_127628 All targets in OG5_127628
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase Get druggable targets OG5_127628 All targets in OG5_127628
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma congolense carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania mexicana carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
Trypanosoma cruzi carbonic anhydrase-like protein, putative Get druggable targets OG5_127628 All targets in OG5_127628
Leishmania donovani carbonic anhydrase-like protein Get druggable targets OG5_127628 All targets in OG5_127628
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma brucei carbonic anhydrase-like protein carbonic anhydrase I 261 aa 281 aa 25.3 %
Brugia malayi Carbonic anhydrase like protein 2 precursor carbonic anhydrase II 260 aa 259 aa 32.0 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Tubulin beta-1 chain 0.0787 0.4937 1
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0041 0.0176 0.0351
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0143 0.0277
Trichomonas vaginalis conserved hypothetical protein 0.0202 0.12 0.2421
Schistosoma mansoni tubulin subunit alpha 0.0202 0.12 0.2426
Leishmania major beta tubulin 0.0787 0.4937 1
Echinococcus multilocularis L aminoadipate semialdehyde 0.0162 0.0947 0.0941
Schistosoma mansoni cpg binding protein 0.0028 0.0092 0.0179
Brugia malayi MH2 domain containing protein 0.0024 0.0065 0.0126
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0044
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0207 0.0408
Loa Loa (eye worm) tubulin alpha 2 0.0145 0.0838 0.1693
Schistosoma mansoni retinoic acid receptor RXR 0.0184 0.1086 0.2193
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.102 0.2055
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0029 0.0096 0.019
Echinococcus multilocularis tubulin gamma 1 chain 0.0467 0.2894 0.289
Mycobacterium leprae cell division protein FtsZ 0.0202 0.12 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.026 0.0522
Onchocerca volvulus 0.0018 0.0024 0.0052
Giardia lamblia Alpha-tubulin 0.0585 0.3651 0.7387
Loa Loa (eye worm) hypothetical protein 0.0101 0.0555 0.112
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0162 0.0947 0.1913
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0015 0.0017
Brugia malayi protein C24B5.3 0.0018 0.0024 0.0044
Echinococcus granulosus tyrosine protein kinase ABL1 0.0214 0.1276 0.2574
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0045 0.0078
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0324 0.065
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0061 0.0118
Trichomonas vaginalis tubulin beta chain, putative 0.0787 0.4937 1
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.006 0.0385
Entamoeba histolytica hypothetical protein 0.007 0.036 0.0729
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0081 0.0158
Entamoeba histolytica cysteine protease, putative 0.0016 0.0017 0.0034
Trypanosoma brucei alpha tubulin 0.0585 0.3651 0.7392
Trypanosoma cruzi tubulin delta chain 0.0365 0.2241 0.4536
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0044 0.0193 0.0384
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0044 0.0194 0.038
Leishmania major beta tubulin 0.0787 0.4937 1
Echinococcus multilocularis tyrosine protein kinase Blk 0.004 0.0171 0.0165
Brugia malayi hypothetical protein 0.0018 0.0024 0.0044
Brugia malayi nuclear hormone receptor 0.0087 0.0471 0.0948
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0017 0.0021
Giardia lamblia Alpha-tubulin 0.0585 0.3651 0.7387
Loa Loa (eye worm) TK protein kinase 0.0034 0.0129 0.0255
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.1514 0.3057
Brugia malayi SPARC precursor 0.0037 0.015 0.0299
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0017 0.0021
Brugia malayi Tyrosine-protein kinase abl-1 0.0124 0.0707 0.1428
Entamoeba histolytica hypothetical protein 0.007 0.036 0.0729
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0214 0.1281 0.2589
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0136 0.0268
Trichomonas vaginalis DNA helicase recq1, putative 0.004 0.0169 0.033
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0017 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0087 0.0471 0.0948
Trichomonas vaginalis tubulin alpha chain, putative 0.0239 0.1438 0.2903
Echinococcus multilocularis carbonic anhydrase 0.0101 0.0555 0.0549
Toxoplasma gondii alpha tubulin TUBA1 0.0585 0.3651 0.7393
Echinococcus granulosus lamin dm0 0.0026 0.0081 0.0151
Echinococcus multilocularis protein dispatched 1 0.0141 0.0816 0.081
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0135 0.0262
Brugia malayi hypoxia-induced factor 1 0.0147 0.0852 0.1721
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0037 0.015 0.0297
Brugia malayi nuclear hormone receptor 0.0041 0.0176 0.0351
Echinococcus multilocularis tubulin alpha chain 0.0585 0.3651 0.3647
Echinococcus multilocularis tubulin alpha 0.0441 0.2726 0.2721
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0015 0.0023
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0107 0.021
Brugia malayi Cathepsin L-like precursor 0.0016 0.0017 0.0029
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0024 0.0065 0.0058
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0016 0.0017 0.0029
Echinococcus granulosus histone acetyltransferase KAT2B 0.0137 0.0786 0.1581
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0293 0.0586
Echinococcus granulosus survival motor neuron protein 1 0.0231 0.1388 0.2801
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0017 0.0021
Mycobacterium leprae Probable lipase LipE 0.0105 0.0586 0.4612
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0214 0.1281 0.2589
Trypanosoma brucei alpha tubulin 0.0585 0.3651 0.7392
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0048 0.0222 0.0444
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0091 0.0179
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0064 0.0324 0.0652
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0124 0.0246
Loa Loa (eye worm) ctsf protein 0.0016 0.0017 0.0029
Schistosoma mansoni carbonic anhydrase-related 0.0101 0.0555 0.1118
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0105 0.0586 0.1181
Loa Loa (eye worm) hypothetical protein 0.0347 0.2126 0.4302
Trypanosoma cruzi zeta tubulin, putative 0.0474 0.2941 0.5953
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0017 0.0021
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0251 0.1514 0.3062
Brugia malayi Cathepsin L-like precursor 0.0016 0.0017 0.0029
Schistosoma mansoni DNA helicase recq1 0.0028 0.0091 0.0177
Loa Loa (eye worm) TK/ABL protein kinase 0.0214 0.1276 0.258
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0196 0.039
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0044
Trypanosoma cruzi alpha tubulin, putative 0.0585 0.3651 0.7393
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0048 0.0222 0.0444
Onchocerca volvulus Putative organic anion transporter 0.0054 0.026 0.1713
Schistosoma mansoni Smad4 0.0024 0.0065 0.0124
Loa Loa (eye worm) hypothetical protein 0.0082 0.0439 0.0884
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.006 0.0385
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0017 0.0021
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0056 0.027 0.0541
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0041 0.0177 0.0351
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0028 0.0091 0.0085
Onchocerca volvulus 0.0028 0.0092 0.0526
Schistosoma mansoni tyrosine kinase 0.0102 0.0562 0.1132
Schistosoma mansoni hypothetical protein 0.0661 0.4133 0.837
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0044 0.0193 0.0378
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0024 0.0065 0.0133
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0228 0.1366 0.2762
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0017 0.0021
Brugia malayi Fibronectin type III domain containing protein 0.0023 0.0061 0.0118
Brugia malayi Tubulin gamma chain 0.0467 0.2894 0.586
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.006 0.0385
Echinococcus multilocularis tubulin alpha 1C chain 0.0585 0.3651 0.3647
Schistosoma mansoni tubulin subunit beta 0.0787 0.4937 1
Echinococcus multilocularis tubulin epsilon chain 0.0467 0.2892 0.2887
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0102 0.0562 0.0556
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0024 0.0065 0.0119
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0044
Brugia malayi CXXC zinc finger family protein 0.0028 0.0092 0.018
Loa Loa (eye worm) nuclear receptor NHR-67 0.0041 0.0176 0.0351
Onchocerca volvulus Putative organic anion transporter 0.0054 0.026 0.1713
Plasmodium falciparum ataxin-2 like protein, putative 0.0098 0.054 0.1068
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.006 0.0385
Toxoplasma gondii patched family protein 0.0018 0.0024 0.0042
Toxoplasma gondii LsmAD domain-containing protein 0.0098 0.054 0.1088
Echinococcus multilocularis survival motor neuron protein 1 0.0231 0.1388 0.1382
Onchocerca volvulus 0.0047 0.0213 0.1382
Plasmodium falciparum alpha tubulin 2 0.0585 0.3651 0.7387
Schistosoma mansoni hypothetical protein 0.0123 0.0698 0.1407
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0087 0.0471 0.0948
Brugia malayi Patched family protein 0.0018 0.0024 0.0044
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.0143 0.0277
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0107 0.0204
Onchocerca volvulus 0.0018 0.0024 0.0052
Trypanosoma brucei beta tubulin 0.0787 0.4937 1
Schistosoma mansoni hypothetical protein 0.0044 0.0194 0.0386
Trypanosoma brucei epsilon tubulin 0.0467 0.2892 0.5852
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0044
Echinococcus multilocularis Immunoglobulin 0.002 0.0043 0.0037
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0101 0.0555 0.112
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0023
Echinococcus multilocularis beta tubulin 0.0787 0.4937 0.4934
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0041 0.0176 0.0169
Echinococcus granulosus Niemann Pick C1 protein 0.0413 0.2548 0.5154
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0087 0.0471 0.0948
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0044
Echinococcus multilocularis GPCR, family 2 0.0015 0.001 0.0004
Schistosoma mansoni hypothetical protein 0.0033 0.0124 0.0244
Echinococcus granulosus tyrosine protein kinase Lyn 0.0047 0.0212 0.0417
Echinococcus granulosus neuropeptide s receptor 0.046 0.2852 0.5771
Echinococcus multilocularis Niemann Pick C1 protein 0.0413 0.2548 0.2543
Trypanosoma cruzi cysteine peptidase, putative 0.0016 0.0017 0.0027
Onchocerca volvulus 0.0239 0.1438 1
Toxoplasma gondii transporter, major facilitator family protein 0.0054 0.026 0.0521
Loa Loa (eye worm) BEN-1 protein 0.0787 0.4937 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0017 0.0021
Brugia malayi Patched family protein 0.0018 0.0024 0.0044
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0046 0.0203 0.0405
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0062 0.0306 0.03
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0017 0.0021
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0015 0.0023
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0017 0.0027
Echinococcus multilocularis FTZ F1 alpha 0.0087 0.0471 0.0464
Schistosoma mansoni smad1 5 8 and 0.0024 0.0065 0.0124
Schistosoma mansoni hypothetical protein 0.0032 0.0117 0.0231
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0184 0.1086 0.2189
Leishmania major trypanothione reductase 0.0046 0.0207 0.0408
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0046 0.0203 0.1591
Echinococcus granulosus carbonic anhydrase 0.0101 0.0555 0.1113
Toxoplasma gondii beta tubulin 0.0787 0.4937 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0044
Brugia malayi Patched family protein 0.0018 0.0024 0.0044
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0023 0.0062 0.0119
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0041 0.0176 0.0351
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0044
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.1514 0.3057
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0062 0.0306 0.0607
Brugia malayi MH1 domain containing protein 0.0024 0.0065 0.0126
Schistosoma mansoni integrin alpha-ps 0.0067 0.034 0.0682
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0017 0.0021
Echinococcus granulosus intermediate filament protein 0.0026 0.0081 0.0151
Onchocerca volvulus 0.0018 0.0024 0.0052
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0023
Echinococcus granulosus Nuclear hormone receptor HR96 0.0041 0.0176 0.0343
Leishmania major alpha tubulin 0.0585 0.3651 0.7392
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0064 0.0324 0.0652
Echinococcus multilocularis beta tubulin 0.0787 0.4937 0.4934
Loa Loa (eye worm) hypothetical protein 0.0082 0.0439 0.0884
Schistosoma mansoni transcription factor LCR-F1 0.007 0.036 0.0723
Treponema pallidum ATP-dependent RNA helicase 0.0024 0.0065 0.0514
Loa Loa (eye worm) hypothetical protein 0.0024 0.0065 0.0127
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0046 0.0203 0.0405
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.0176 0.0343
Loa Loa (eye worm) hypothetical protein 0.0105 0.0586 0.1182
Brugia malayi nuclear receptor NHR-88 0.0041 0.0176 0.0351
Schistosoma mansoni hypothetical protein 0.0015 0.001 0.0014
Onchocerca volvulus 0.0054 0.026 0.1713
Brugia malayi Nuclear hormone receptor E75 0.0041 0.0176 0.0351
Loa Loa (eye worm) hypothetical protein 0.0041 0.0176 0.0351
Echinococcus granulosus Immunoglobulin 0.002 0.0043 0.0074
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.002 0.0043 0.008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0087 0.0471 0.0948
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0015 0.0017
Echinococcus multilocularis neuroglian 0.0023 0.0062 0.0055
Echinococcus multilocularis roundabout 2 0.0029 0.0098 0.0092
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.1514 0.3057
Brugia malayi beta-lactamase 0.0105 0.0586 0.1182
Trichomonas vaginalis tubulin gamma chain, putative 0.0787 0.4937 1
Brugia malayi hypothetical protein 0.0098 0.054 0.109
Echinococcus granulosus thyroid hormone receptor alpha 0.0041 0.0176 0.0343
Echinococcus granulosus tubulin alpha chain 0.0585 0.3651 0.7392
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0017 0.0005
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0044
Echinococcus granulosus tubulin delta chain 0.0202 0.12 0.2421
Giardia lamblia Beta tubulin 0.0787 0.4937 1
Leishmania major hypothetical protein, conserved 0.0098 0.054 0.1083
Trypanosoma brucei zeta tubulin 0.0474 0.2941 0.5951
Trichomonas vaginalis tubulin beta chain, putative 0.0585 0.3651 0.7392
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0143 0.0277
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0044
Schistosoma mansoni lamin 0.0026 0.0081 0.0157
Plasmodium falciparum thioredoxin reductase 0.0046 0.0207 0.0392
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0017 0.0021
Trichomonas vaginalis tubulin epsilon chain, putative 0.0585 0.3651 0.7392
Loa Loa (eye worm) fibroinase 0.0016 0.0017 0.0029
Schistosoma mansoni organic anion transporter 0.0054 0.026 0.0521
Loa Loa (eye worm) patched family protein 0.0018 0.0024 0.0044
Schistosoma mansoni single-minded 0.0048 0.0216 0.0431
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0044
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0324 0.065
Echinococcus multilocularis Smad4 0.0024 0.0065 0.0058
Brugia malayi Patched family protein 0.0018 0.0024 0.0044
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0015 0.0017
Schistosoma mansoni tyrosine kinase 0.0097 0.0531 0.1069
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0214 0.1281 0.2589
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0141 0.0811 0.1637
Leishmania major phosphopantetheinyl transferase-like protein 0.0046 0.0203 0.0399
Loa Loa (eye worm) hypothetical protein 0.0585 0.3651 0.7394
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0044
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0963 0.194
Brugia malayi Cathepsin L-like precursor 0.0016 0.0017 0.0029
Loa Loa (eye worm) hypothetical protein 0.0054 0.026 0.0522
Loa Loa (eye worm) hypothetical protein 0.0113 0.0634 0.128
Schistosoma mansoni tyrosine kinase 0.0018 0.003 0.0054
Loa Loa (eye worm) hypothetical protein 0.0101 0.0555 0.112
Echinococcus multilocularis tubulin alpha chain 0.0585 0.3651 0.3647
Plasmodium vivax glutathione reductase, putative 0.0046 0.0207 0.042
Echinococcus multilocularis musashi 0.0026 0.0081 0.0074
Entamoeba histolytica hypothetical protein 0.007 0.036 0.0729
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0138 0.0791 0.0785
Brugia malayi hypothetical protein 0.0023 0.0061 0.0118
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0064 0.0324 0.065
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0016 0.0017 0.0029
Brugia malayi tubulin alpha-2 chain 0.0585 0.3651 0.7394
Echinococcus multilocularis expressed protein 0.0037 0.015 0.0144
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0293 0.1785 0.3611
Leishmania major alpha tubulin 0.0585 0.3651 0.7392
Loa Loa (eye worm) tubulin beta chain 0.0787 0.4937 1
Trichomonas vaginalis conserved hypothetical protein 0.0202 0.12 0.2421
Schistosoma mansoni alpha tubulin 0.0585 0.3651 0.7393
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0017 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.008 0.0149
Trichomonas vaginalis D-aminoacylase, putative 0.0105 0.0586 0.1175
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0062 0.0306 0.062
Schistosoma mansoni tyrosine kinase 0.0155 0.0902 0.1821
Brugia malayi MH2 domain containing protein 0.035 0.2149 0.4349
Brugia malayi SRC-1 0.0047 0.0212 0.0425
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0044 0.0193 0.0391
Leishmania major beta tubulin 0.0787 0.4937 1
Trichomonas vaginalis tubulin, putative 0.0239 0.1438 0.2903
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0015 0.0023
Brugia malayi Calcitonin receptor-like protein seb-1 0.0048 0.0222 0.0444
Onchocerca volvulus 0.0035 0.0137 0.0846
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0017 0.0034
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0024 0.0065 0.0339
Plasmodium vivax tubulin epsilon chain, putative 0.0467 0.2892 0.5857
Mycobacterium tuberculosis Conserved protein 0.0105 0.0586 0.136
Leishmania major beta tubulin 0.0787 0.4937 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0121 0.0232
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.031 0.0617
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0056 0.027 0.0609
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0207 0.0459
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0221 0.0441
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0087 0.0471 0.0941
Trichomonas vaginalis tubulin beta chain, putative 0.0585 0.3651 0.7392
Brugia malayi Kelch motif family protein 0.0046 0.0209 0.0419
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0087 0.0471 0.0948
Loa Loa (eye worm) patched family protein 0.0018 0.0024 0.0044
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0101 0.0555 0.112
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0324 0.0645
Brugia malayi Cathepsin L-like precursor 0.0016 0.0017 0.0029
Onchocerca volvulus 0.0105 0.0586 0.4005
Mycobacterium leprae conserved hypothetical protein 0.0105 0.0586 0.4612
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.001 0.0016
Schistosoma mansoni hypothetical protein 0.0015 0.001 0.0014
Brugia malayi alpha-tubulin 0.0585 0.3651 0.7394
Echinococcus multilocularis tubulin alpha 3 chain 0.0585 0.3651 0.3647
Loa Loa (eye worm) hypothetical protein 0.0035 0.0135 0.0269
Schistosoma mansoni vesicular amine transporter 0.002 0.0043 0.008
Brugia malayi Nuclear hormone receptor-like 1 0.0046 0.0207 0.0415
Giardia lamblia Beta tubulin 0.0787 0.4937 1
Brugia malayi bHLH-PAS transcription factor 0.0035 0.0137 0.0273
Echinococcus granulosus Tubulin beta 2C chain 0.0787 0.4937 1
Echinococcus granulosus tubulin alpha 1C chain 0.0585 0.3651 0.7392
Brugia malayi Immunoglobulin I-set domain containing protein 0.0029 0.0096 0.019
Entamoeba histolytica recQ family helicase, putative 0.0031 0.0107 0.0217
Trichomonas vaginalis tubulin beta chain, putative 0.0239 0.1438 0.2903
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0105 0.0585 0.1358
Leishmania major alpha tubulin 0.0585 0.3651 0.7392
Echinococcus multilocularis c src tyrosine kinase 0.0018 0.003 0.0024
Treponema pallidum cell division protein FtsZ 0.0202 0.12 1
Trypanosoma brucei hypothetical protein, conserved 0.0105 0.0586 0.1175
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0105 0.0586 0.136
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0037 0.015 0.0297
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0087 0.0471 0.0948
Loa Loa (eye worm) hypothetical protein 0.0033 0.0124 0.0246
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0006 0.0006
Loa Loa (eye worm) tubulin beta chain 0.0202 0.12 0.2427
Echinococcus granulosus geminin 0.0661 0.4133 0.8369
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0087 0.0471 0.0948
Mycobacterium ulcerans hypothetical protein 0.0023 0.006 0.0385
Onchocerca volvulus 0.0018 0.0024 0.0052
Brugia malayi orphan nuclear receptor NR2E1 0.0041 0.0176 0.0351
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0041 0.0176 0.1118
Echinococcus granulosus tubulin beta 1 chain 0.0787 0.4937 1
Onchocerca volvulus 0.0105 0.0586 0.4005
Schistosoma mansoni lamin 0.0026 0.0081 0.0157
Echinococcus granulosus alpha tubulin 0.0585 0.3651 0.7392
Schistosoma mansoni tubulin subunit delta 0.0202 0.12 0.2426
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0054 0.026 0.0254
Loa Loa (eye worm) MH1 domain-containing protein 0.0024 0.0065 0.0126
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0046 0.0207 0.0407
Loa Loa (eye worm) tubulin alpha 2 0.0384 0.2363 0.4784
Trypanosoma cruzi hypothetical protein, conserved 0.0105 0.0586 0.1181
Echinococcus multilocularis tubulin alpha 1C chain 0.0585 0.3651 0.3647
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.006 0.0109
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0044
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0062 0.0306 0.0613
Schistosoma mansoni integrin alpha-ps 0.0035 0.0135 0.0267
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0087 0.0471 0.0941
Echinococcus granulosus epidermal growth factor receptor 0.016 0.0936 0.1885
Echinococcus multilocularis 0.009 0.0488 0.0482
Loa Loa (eye worm) hypothetical protein 0.0105 0.0586 0.1182
Brugia malayi Cathepsin L-like precursor 0.0016 0.0017 0.0029
Toxoplasma gondii cathepsin CPL 0.0016 0.0017 0.0027
Loa Loa (eye worm) hypothetical protein 0.0162 0.0947 0.1913
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0017 0.0021
Mycobacterium ulcerans putative regulatory protein 0.0035 0.0137 0.1032
Giardia lamblia Beta tubulin 0.0787 0.4937 1
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0015 0.0008
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0044
Loa Loa (eye worm) tubulin alpha chain 0.0585 0.3651 0.7394
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0017
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0105 0.0586 0.136
Loa Loa (eye worm) SRC-1 0.0047 0.0212 0.0425
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0044
Plasmodium vivax vivapain-2 0.0016 0.0017 0.0034
Mycobacterium tuberculosis Conserved protein 0.0105 0.0586 0.136
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0056 0.027 0.2157
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0087 0.0471 0.0464
Trichomonas vaginalis DNA helicase recq, putative 0.004 0.0169 0.033
Loa Loa (eye worm) hypothetical protein 0.0046 0.0207 0.0415
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0087 0.0471 0.0948
Loa Loa (eye worm) hypoxia-induced factor 1 0.0147 0.0852 0.1721
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0017 0.0021
Echinococcus multilocularis thyroid hormone receptor alpha 0.021 0.1256 0.125
Schistosoma mansoni cell adhesion molecule 0.0026 0.008 0.0155
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0078 0.0146
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.031 0.0617
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0087 0.0471 0.0948
Brugia malayi nuclear receptor RXR 0.0046 0.0207 0.0415
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.01 0.0549 0.0543
Schistosoma mansoni tubulin subunit epsilon 0.0467 0.2892 0.5854
Brugia malayi beta-lactamase family protein 0.0105 0.0586 0.1182
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.001 0.0008
Brugia malayi nuclear hormone receptor family member odr-7 0.0041 0.0176 0.0351
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0017 0.0021
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0105 0.0586 0.1182
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0246 0.0494
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0196 0.0384
Loa Loa (eye worm) hypothetical protein 0.0041 0.0176 0.0351
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0087 0.0471 0.0948
Schistosoma mansoni hypothetical protein 0.0119 0.0675 0.1362
Plasmodium vivax tubulin alpha chain, putative 0.0585 0.3651 0.7395
Loa Loa (eye worm) hypothetical protein 0.0087 0.0471 0.0948
Trichomonas vaginalis tubulin, putative 0.0239 0.1438 0.2903
Brugia malayi hypothetical protein 0.0046 0.0207 0.0415
Mycobacterium tuberculosis Probable oxidoreductase 0.0117 0.0661 0.1537
Brugia malayi glutathione reductase 0.0046 0.0207 0.0415
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0017 0.0021
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0015 0.003
Onchocerca volvulus 0.0054 0.026 0.1713
Trichomonas vaginalis D-aminoacylase, putative 0.0105 0.0586 0.1175
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0024 0.0065 0.0125
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0062 0.0306 0.0592
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0015 0.003
Plasmodium vivax tubulin alpha chain, putative 0.0585 0.3651 0.7395
Schistosoma mansoni tubulin subunit beta 0.0787 0.4937 1
Schistosoma mansoni coup transcription factor 0.0087 0.0471 0.0947
Leishmania major beta tubulin 0.0787 0.4937 1
Schistosoma mansoni tubulin subunit alpha 0.0585 0.3651 0.7393
Giardia lamblia Delta tubulin 0.0202 0.12 0.2408
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0207 0.0201
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0044 0.0193 0.0378
Schistosoma mansoni hypothetical protein 0.0047 0.0213 0.0425
Echinococcus granulosus tubulin alpha chain 0.0585 0.3651 0.7392
Brugia malayi nuclear receptor RXR 0.0041 0.0176 0.0351
Echinococcus multilocularis tyrosine protein kinase Srms 0.004 0.0171 0.0165
Loa Loa (eye worm) hypothetical protein 0.0037 0.015 0.0299
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0143 0.0283
Leishmania major beta tubulin 0.0787 0.4937 1
Loa Loa (eye worm) hypothetical protein 0.0087 0.0471 0.0948
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0006 0.0006
Loa Loa (eye worm) beta-tubulin 0.0787 0.4937 1
Brugia malayi hypothetical protein 0.0041 0.0176 0.0351
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0101 0.0555 0.112
Onchocerca volvulus 0.0026 0.0081 0.0449
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.1514 0.3057
Loa Loa (eye worm) TK protein kinase 0.0105 0.058 0.1171
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0087 0.0471 0.0464
Schistosoma mansoni hypothetical protein 0.0119 0.0675 0.1362
Plasmodium falciparum tubulin gamma chain 0.0467 0.2894 0.585
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0023 0.0017
Loa Loa (eye worm) patched family protein 0.0018 0.0024 0.0044
Schistosoma mansoni nuclear hormone receptor 0.0041 0.0176 0.0349
Trichomonas vaginalis tubulin epsilon chain, putative 0.0787 0.4937 1
Toxoplasma gondii hypothetical protein 0.0101 0.0555 0.1118
Echinococcus multilocularis lamin dm0 0.0026 0.0081 0.0074
Trypanosoma cruzi PAB1-binding protein , putative 0.0098 0.054 0.1088
Echinococcus multilocularis Tubulin beta 2C chain 0.0787 0.4937 0.4934
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0044 0.0193 0.0384
Echinococcus granulosus expressed conserved protein 0.0271 0.1645 0.3323
Loa Loa (eye worm) patched family protein 0.0018 0.0024 0.0044
Loa Loa (eye worm) hypothetical protein 0.0087 0.0471 0.0948
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0041 0.0177 0.0345
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0044
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0041 0.0176 0.1118
Schistosoma mansoni cpg binding protein 0.003 0.0102 0.0199
Brugia malayi Nuclear hormone receptor E75 0.0041 0.0176 0.0351
Schistosoma mansoni hypothetical protein 0.0119 0.0675 0.1362
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0087 0.0471 0.0948
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.0196 0.0392
Brugia malayi Patched related family protein 12 0.0018 0.0024 0.0044
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0143 0.0283
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0102 0.0562 0.0556
Brugia malayi Patched family protein 0.0018 0.0024 0.0044
Schistosoma mansoni blooms syndrome DNA helicase 0.0026 0.0078 0.0151
Loa Loa (eye worm) tubulin gamma chain 0.0467 0.2894 0.586
Onchocerca volvulus 0.0105 0.0586 0.4005
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0023 0.0062 0.0113
Echinococcus granulosus lamin 0.0026 0.0081 0.0151
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0121 0.0232
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0017 0.0021
Echinococcus multilocularis smad 0.0024 0.0065 0.0058
Schistosoma mansoni nuclear hormone receptor 0.0087 0.0471 0.0947
Echinococcus granulosus Niemann Pick C1 protein 0.0289 0.1757 0.3549
Echinococcus granulosus integrin alpha ps 0.0067 0.034 0.0677
Leishmania major cysteine peptidase A (CPA) 0.0016 0.0017 0.0021
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0023 0.002
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0087 0.0471 0.0941
Echinococcus multilocularis carbonic anhydrase 0.0101 0.0555 0.0549
Loa Loa (eye worm) hypothetical protein 0.0041 0.0176 0.0351
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0087 0.0471 0.0948
Loa Loa (eye worm) tubulin alpha 2 0.0384 0.2363 0.4784
Plasmodium vivax delta tubulin, putative 0.0202 0.12 0.2431
Echinococcus granulosus Tubulin beta 2C chain 0.0787 0.4937 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0087 0.0471 0.0948
Plasmodium vivax RNA helicase-1, putative 0.0024 0.0065 0.0132
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0056 0.027 0.0264
Plasmodium falciparum ataxin-2 like protein, putative 0.0098 0.054 0.1068
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0064 0.0116
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0214 0.1276 0.127
Mycobacterium ulcerans esterase/lipase LipP 0.0105 0.0586 0.4819
Echinococcus granulosus insulin growth factor 1 receptor beta 0.01 0.0549 0.11
Echinococcus multilocularis tubulin delta chain 0.0202 0.12 0.1195
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.006 0.0109
Trichomonas vaginalis tubulin beta chain, putative 0.0585 0.3651 0.7392
Mycobacterium tuberculosis Probable lipase LipE 0.0105 0.0586 0.136
Brugia malayi photoreceptor-specific nuclear receptor 0.0087 0.0471 0.0948
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0121 0.0232
Onchocerca volvulus 0.0018 0.0024 0.0052
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.031 0.0617
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0054 0.026 0.0254
Schistosoma mansoni survival motor neuron protein 0.0047 0.0213 0.0425
Brugia malayi Patched family protein 0.0018 0.0024 0.0044
Echinococcus granulosus cathepsin l1 0.0016 0.0017 0.0021
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0087 0.0471 0.0947
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0047 0.0212 0.0417
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0024 0.0065 0.0125
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0062 0.0306 0.0607
Loa Loa (eye worm) hypothetical protein 0.002 0.0043 0.0082
Brugia malayi nuclear receptor NHR-67 0.0041 0.0176 0.0351
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0017 0.0021
Trypanosoma cruzi cruzipain precursor, putative 0.0062 0.031 0.0622
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0087 0.0471 0.0948
Schistosoma mansoni tubulin subunit gamma 0.0467 0.2894 0.5859
Leishmania major alpha tubulin 0.0585 0.3651 0.7392
Trypanosoma brucei zeta tubulin, putative 0.0474 0.2941 0.5951
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0044
Toxoplasma gondii patched family protein 0.0018 0.0024 0.0042
Schistosoma mansoni patched 1 0.0124 0.0704 0.142
Echinococcus granulosus tubulin alpha chain 0.0585 0.3651 0.7392
Treponema pallidum NADH oxidase 0.0016 0.0015 0.0094
Brugia malayi Cathepsin L-like precursor 0.0016 0.0017 0.0029
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0056 0.027 0.2157
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.0143 0.0277
Entamoeba histolytica tubulin family protein 0.0787 0.4937 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0023 0.0041
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0064 0.0324 0.0657
Onchocerca volvulus 0.0037 0.015 0.0936
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0087 0.0471 0.0464
Echinococcus multilocularis Tubulin alpha 1 chain 0.0585 0.3651 0.3647
Leishmania major alpha tubulin 0.0585 0.3651 0.7392
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0135 0.0262
Trichomonas vaginalis tubulin beta chain, putative 0.0585 0.3651 0.7392
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0017 0.001
Loa Loa (eye worm) hypothetical protein 0.0105 0.0586 0.1182
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0087 0.0471 0.0941
Echinococcus multilocularis Tubulin beta 2C chain 0.0787 0.4937 0.4934
Entamoeba histolytica hypothetical protein 0.0046 0.0203 0.0412
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0024 0.0065 0.0102
Plasmodium vivax tubulin gamma chain, putative 0.0467 0.2894 0.5862
Echinococcus multilocularis tubulin subunit TubB 0.0585 0.3651 0.3647
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.006 0.0385
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0152 0.0295
Trypanosoma brucei tubulin delta chain 0.0365 0.2241 0.4532
Echinococcus granulosus cathepsin l cysteine peptidase 0.0016 0.0017 0.0021
Echinococcus multilocularis integrin alpha ps 0.0067 0.034 0.0334
Brugia malayi hypothetical protein 0.0218 0.1306 0.2642
Loa Loa (eye worm) TK protein kinase 0.004 0.0171 0.0341
Loa Loa (eye worm) hypothetical protein 0.0046 0.0207 0.0415
Loa Loa (eye worm) hypothetical protein 0.0041 0.0176 0.0351
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0087 0.0471 0.0948
Trypanosoma brucei alpha tubulin 0.0585 0.3651 0.7392
Brugia malayi Tubulin alpha chain 0.0585 0.3651 0.7394
Echinococcus multilocularis integrin alpha 3 0.0115 0.0644 0.0638
Loa Loa (eye worm) hypothetical protein 0.0016 0.0017 0.0029
Schistosoma mansoni carbonic anhydrase-related 0.0101 0.0555 0.1118
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0155 0.0313
Leishmania major alpha tubulin 0.0585 0.3651 0.7392
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0136 0.0262
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0087 0.0471 0.0941
Brugia malayi Patched family protein 0.0018 0.0024 0.0044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0101 0.0191
Onchocerca volvulus 0.0018 0.0024 0.0052
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.0023 0.007
Echinococcus granulosus beta tubulin 0.0787 0.4937 1
Brugia malayi Patched related family protein 4 0.0018 0.0024 0.0044
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0101 0.0555 0.112
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0213 0.0427
Echinococcus multilocularis integrin alpha ps 0.0067 0.034 0.0334
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.006 0.0122
Trypanosoma cruzi epsilon tubulin, putative 0.0467 0.2892 0.5854
Trypanosoma cruzi tubulin delta chain 0.0365 0.2241 0.4536
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0037 0.015 0.0297
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0091 0.0177
Entamoeba histolytica recQ family DNA helicase 0.0014 0.0003 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0064 0.0116
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0024 0.0065 0.0125
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0087 0.0471 0.3193
Schistosoma mansoni tyrosine kinase 0.0047 0.0212 0.0423
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.0143 0.029
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0047 0.0212 0.0206
Schistosoma mansoni nephrin 0.0026 0.008 0.0154
Echinococcus granulosus Tubulin beta 2C chain 0.0787 0.4937 1
Loa Loa (eye worm) transcription factor SMAD2 0.035 0.2149 0.4349
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0136 0.0262
Brugia malayi Patched family protein 0.0018 0.0024 0.0044
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0117 0.0661 0.5265
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0041 0.0176 0.0349
Echinococcus granulosus cathepsin L cysteine proteinase 0.0016 0.0017 0.0021
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.031 0.0617
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0017 0.0021
Brugia malayi Bloom's syndrome protein homolog 0.004 0.0169 0.0338
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0105 0.0586 0.4819
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0143 0.0277
Echinococcus granulosus tyrosine protein kinase Src42A 0.0035 0.0137 0.0264
Trypanosoma cruzi MFS transporter, putative 0.0054 0.026 0.0521
Echinococcus granulosus integrin beta 2 0.0227 0.136 0.2745
Echinococcus multilocularis tubulin subunit beta 0.0787 0.4937 0.4934
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0018 0.0029 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0121 0.0232
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0016
Loa Loa (eye worm) integrin beta-2 0.0306 0.1867 0.3777
Echinococcus granulosus tumor protein p63 0.033 0.2021 0.4085
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0044 0.0193 0.0391
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0384 0.2363 0.4784
Echinococcus granulosus follistatin 0.0037 0.015 0.0291
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.031 0.0617
Loa Loa (eye worm) hypothetical protein 0.0041 0.0176 0.0351
Onchocerca volvulus Glucosylceramidase homolog 0.0165 0.0963 0.6658
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0006 0.0006
Plasmodium vivax ataxin-2 like protein, putative 0.0098 0.054 0.1094
Echinococcus granulosus histone acetyltransferase KAT2B 0.0041 0.0177 0.0345
Loa Loa (eye worm) hypothetical protein 0.0231 0.1388 0.2807
Plasmodium vivax hypothetical protein, conserved 0.0105 0.0586 0.1187
Echinococcus granulosus tubulin alpha 1C chain 0.0585 0.3651 0.7392
Loa Loa (eye worm) TK/EGFR protein kinase 0.0295 0.1797 0.3637
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0143 0.0277
Brugia malayi PAS domain containing protein 0.0048 0.0216 0.0432
Brugia malayi hypothetical protein 0.0041 0.0176 0.0351
Entamoeba histolytica tubulin family protein 0.0787 0.4937 1
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0143 0.0137
Echinococcus granulosus tyrosine protein kinase HCK 0.0034 0.0129 0.0248
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0087 0.0471 0.0947
Loa Loa (eye worm) nuclear hormone receptor 0.0041 0.0176 0.0351
Loa Loa (eye worm) hypothetical protein 0.0046 0.0207 0.0415
Echinococcus granulosus Tubulin beta 2C chain 0.0787 0.4937 1
Schistosoma mansoni smad 0.0024 0.0065 0.0124
Trichomonas vaginalis tubulin epsilon chain, putative 0.0585 0.3651 0.7392
Loa Loa (eye worm) hypothetical protein 0.0037 0.015 0.0299
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0963 0.194
Loa Loa (eye worm) hypothetical protein 0.0023 0.0061 0.0118
Echinococcus multilocularis Immunoglobulin 0.002 0.0043 0.0037
Loa Loa (eye worm) hypothetical protein 0.0023 0.006 0.0117
Brugia malayi AMP-binding enzyme family protein 0.0023 0.006 0.0117
Loa Loa (eye worm) hypothetical protein 0.0046 0.0207 0.0415
Leishmania major cathepsin L-like protease 0.0062 0.031 0.0617
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0081 0.0158
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0225 0.045
Schistosoma mansoni hypothetical protein 0.0015 0.001 0.0014
Echinococcus granulosus Protein patched homolog 1 0.0124 0.0704 0.1414
Loa Loa (eye worm) hypothetical protein 0.0046 0.0209 0.0419
Loa Loa (eye worm) hypothetical protein 0.0054 0.026 0.0522
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.0024 0.0065 0.0119
Loa Loa (eye worm) hypothetical protein 0.0026 0.0078 0.0152
Echinococcus multilocularis neuropeptide s receptor 0.046 0.2852 0.2847
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0015 0.0017
Loa Loa (eye worm) hypothetical protein 0.0098 0.054 0.109
Echinococcus multilocularis tubulin alpha chain 0.0585 0.3651 0.3647
Plasmodium falciparum carbonic anhydrase 0.0101 0.0555 0.1098
Schistosoma mansoni integrin alpha 0.0149 0.0867 0.1749
Leishmania major alpha tubulin 0.0585 0.3651 0.7392
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0056 0.027 0.0535
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0017 0.0021
Loa Loa (eye worm) hypothetical protein 0.0105 0.0586 0.1182
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0047 0.0212 0.0206
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0963 0.194
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0365 0.2241 0.4536
Schistosoma mansoni hypothetical protein 0.0101 0.0558 0.1124
Echinococcus granulosus Tubulin alpha 1 chain 0.0585 0.3651 0.7392
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0674 0.4216 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.031 0.0617
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0015 0.0017
Loa Loa (eye worm) tubulin alpha-3 chain 0.0347 0.2126 0.4302
Brugia malayi sulfakinin receptor protein 0.0218 0.1306 0.2642
Loa Loa (eye worm) hypothetical protein 0.0054 0.026 0.0522
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0046 0.0203 0.1591
Brugia malayi Protein kinase domain containing protein 0.0097 0.0531 0.1071
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0087 0.0471 0.0947
Brugia malayi hypothetical protein 0.007 0.036 0.0724
Trichomonas vaginalis DNA helicase recq, putative 0.0031 0.0107 0.0204
Brugia malayi prostaglandin transporter 0.0054 0.026 0.0522
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0105 0.0585 0.1358
Loa Loa (eye worm) carbonic anhydrase 3 0.0214 0.1281 0.2591
Onchocerca volvulus Protein ultraspiracle homolog 0.0087 0.0471 0.3193
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0016 0.0017 0.0005
Echinococcus multilocularis insulin receptor 0.0097 0.0531 0.0525
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0037 0.015 0.0297
Brugia malayi Tyrosine-protein kinase abl-1 0.0095 0.0522 0.1053
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0018 0.003 0.0024
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0105 0.0586 0.136
Trypanosoma brucei tubulin gamma chain 0.0467 0.2894 0.5857
Leishmania major cathepsin L-like protease 0.0062 0.031 0.0617
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0056 0.027 0.0543
Entamoeba histolytica tubulin gamma chain 0.0467 0.2894 0.5862
Toxoplasma gondii isocitrate dehydrogenase 0.0062 0.0306 0.0613
Mycobacterium tuberculosis Probable hydrolase 0.0105 0.0586 0.136
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0046 0.0203 0.0383
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0117 0.0661 0.1537
Trichomonas vaginalis tubulin, putative 0.0228 0.1369 0.2763
Echinococcus granulosus Tubulin alpha 1 chain 0.0585 0.3651 0.7392
Schistosoma mansoni intermediate filament proteins 0.0026 0.0081 0.0157
Echinococcus multilocularis mothers against decapentaplegic 5 0.0024 0.0065 0.0058
Echinococcus multilocularis cysteine protease 0.0016 0.0017 0.001
Brugia malayi ecdysone receptor 0.0041 0.0176 0.0351
Mycobacterium tuberculosis Conserved protein 0.0105 0.0586 0.136
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0017 0.0023 0.044
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0044
Toxoplasma gondii isocitrate dehydrogenase 0.0062 0.0306 0.0613
Loa Loa (eye worm) alpha-tubulin 0.0585 0.3651 0.7394
Leishmania major epsilon tubulin, putative 0.0467 0.2892 0.5852
Echinococcus granulosus Tubulin alpha 1 chain 0.0585 0.3651 0.7392
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0441 0.2726 0.5518
Trichomonas vaginalis tubulin gamma chain, putative 0.0202 0.12 0.2421
Echinococcus multilocularis expressed conserved protein 0.0271 0.1645 0.1639
Echinococcus granulosus defective proboscis extension response 0.002 0.0043 0.0074
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0017 0.0027
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0091 0.0177
Echinococcus granulosus carbonic anhydrase 0.0101 0.0555 0.1113
Brugia malayi Niemann-Pick C1 protein precursor 0.0289 0.1757 0.3554
Brugia malayi sodium-independent organic anion transporter family protein 0.0054 0.026 0.0522
Echinococcus multilocularis tubulin alpha 3 chain 0.0585 0.3651 0.3647
Leishmania major beta tubulin 0.0787 0.4937 1
Brugia malayi hypothetical protein 0.0018 0.0024 0.0044
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0023 0.0046
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0143 0.0277
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0046 0.0209 0.0419
Echinococcus granulosus ecdysone induced protein 78C 0.0087 0.0471 0.0941
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0054 0.026 0.0515
Echinococcus multilocularis transcription factor Dp 1 0.0037 0.0151 0.0144
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0015 0.0017
Echinococcus granulosus tubulin beta 4A class IVa 0.0787 0.4937 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0176 0.0351
Leishmania major beta tubulin 0.0787 0.4937 1
Schistosoma mansoni hypothetical protein 0.0101 0.0555 0.1118
Plasmodium falciparum tubulin delta chain, putative 0.0202 0.12 0.2408
Loa Loa (eye worm) DR-78 0.0041 0.0176 0.0351
Brugia malayi protein C24B5.3 0.0018 0.0024 0.0044
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0044
Echinococcus granulosus tm gpcr rhodopsin 0.0516 0.3211 0.6498
Echinococcus granulosus dnaJ subfamily B 0.04 0.2464 0.4985
Echinococcus multilocularis lamin 0.0026 0.0081 0.0074
Echinococcus granulosus tubulin gamma 1 chain 0.0467 0.2894 0.5857
Echinococcus granulosus Tubulin beta 2C chain 0.0787 0.4937 1
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0384 0.2363 0.478
Onchocerca volvulus 0.0026 0.0081 0.0449
Schistosoma mansoni tyrosine kinase 0.0047 0.0212 0.0423
Brugia malayi Tubulin alpha-2 chain 0.0585 0.3651 0.7394
Loa Loa (eye worm) hypothetical protein 0.0159 0.0931 0.1881
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0044
Echinococcus granulosus neuroglian 0.0023 0.0062 0.0112
Echinococcus granulosus FTZ F1 alpha 0.0087 0.0471 0.0941
Loa Loa (eye worm) glutathione reductase 0.0046 0.0207 0.0415
Echinococcus granulosus GPCR family 2 0.0015 0.001 0.0008
Loa Loa (eye worm) tubulin beta-4 chain 0.0787 0.4937 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.026 0.0522
Brugia malayi Patched family protein 0.0018 0.0024 0.0044
Loa Loa (eye worm) hypothetical protein 0.0087 0.0471 0.0948
Onchocerca volvulus 0.0054 0.026 0.1713
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0044 0.0193 0.0384
Schistosoma mansoni integrin beta subunit 0.018 0.1063 0.2148
Brugia malayi Tubulin beta chain 0.0239 0.1438 0.2909
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.031 0.0622
Onchocerca volvulus Protein patched homolog 0.0018 0.0024 0.0052
Brugia malayi isocitrate dehydrogenase 0.0062 0.0306 0.0615
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.0024 0.0065 0.012
Schistosoma mansoni tyrosine kinase 0.0295 0.1797 0.3635
Trypanosoma brucei epsilon tubulin 0.0467 0.2892 0.5852
Loa Loa (eye worm) hypothetical protein 0.0101 0.0555 0.112
Brugia malayi sodium-independent organic anion transporter family protein 0.0054 0.026 0.0522
Schistosoma mansoni nuclear receptor 0.0041 0.0176 0.0349
Echinococcus granulosus beta LACTamase domain containing family member 0.0105 0.0586 0.1175
Brugia malayi Tubulin beta chain 0.0202 0.12 0.2427
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0123 0.0698 0.1402
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0017 0.0021
Toxoplasma gondii ABC1 family protein 0.0105 0.0586 0.1181
Echinococcus granulosus insulin receptor 0.0097 0.0531 0.1063
Schistosoma mansoni carbonic anhydrase 0.0101 0.0555 0.1118
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0064 0.0116
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.031 0.0617
Loa Loa (eye worm) Smad1 0.0024 0.0065 0.0126
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0044
Loa Loa (eye worm) hypothetical protein 0.0087 0.0471 0.0948
Brugia malayi hypothetical protein 0.0054 0.026 0.0522
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0015 0.0025
Echinococcus granulosus tubulin alpha chain 0.0585 0.3651 0.7392
Echinococcus granulosus tubulin subunit TubB 0.0585 0.3651 0.7392
Onchocerca volvulus 0.0041 0.0176 0.1118
Toxoplasma gondii protease inhibitor PI2 0.0037 0.015 0.0297
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0018 0.003 0.0048
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0044
Schistosoma mansoni tyrosine kinase 0.0018 0.003 0.0054
Echinococcus multilocularis cpg binding protein 0.003 0.0102 0.0095
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0015 0.0017
Loa Loa (eye worm) hypothetical protein 0.0017 0.0023 0.0041
Brugia malayi AMP-binding enzyme family protein 0.0023 0.006 0.0117
Loa Loa (eye worm) integrin alpha pat-2 0.023 0.1383 0.2798
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0047 0.0212 0.0206
Echinococcus granulosus Solute carrier organic anion transporter family 0.0054 0.026 0.0515
Schistosoma mansoni steroid hormone receptor ad4bp 0.0087 0.0471 0.0947
Brugia malayi protein-tyrosine kinase 0.004 0.0171 0.0341
Trichomonas vaginalis tubulin beta chain, putative 0.0585 0.3651 0.7392
Brugia malayi Latrophilin receptor protein 2 0.0015 0.001 0.0016
Echinococcus granulosus integrin alpha ps 0.0032 0.0117 0.0225
Mycobacterium ulcerans lipase LipD 0.0105 0.0586 0.4819
Echinococcus granulosus Nuclear hormone receptor HR96 0.0041 0.0176 0.0343
Echinococcus multilocularis peroxisome assembly protein 26 0.0585 0.3651 0.3647
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0047 0.0212 0.0206
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0006 0.0008
Brugia malayi eukaryotic initiation factor 4A 0.0024 0.0065 0.0127
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0044
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0087 0.0471 0.0947
Loa Loa (eye worm) tubulin beta-2A chain 0.0787 0.4937 1
Echinococcus multilocularis protein patched 0.0124 0.0704 0.0698
Echinococcus granulosus beta tubulin 0.0787 0.4937 1
Schistosoma mansoni tubulin subunit beta 0.0787 0.4937 1
Leishmania major beta tubulin 0.0787 0.4937 1
Giardia lamblia Gamma tubulin 0.0467 0.2894 0.585
Leishmania major zeta tubulin, putative 0.0474 0.2941 0.5951
Trichomonas vaginalis tubulin alpha chain, putative 0.0441 0.2726 0.5515
Brugia malayi conserved hypotetical protein 0.0041 0.0176 0.0351
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0787 0.4937 0.4934
Brugia malayi tailless protein 0.0041 0.0176 0.0351
Loa Loa (eye worm) tubulin alpha chain 0.0585 0.3651 0.7394
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0135 0.0262
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0064 0.0116
Loa Loa (eye worm) agrin synaptic family protein 0.0037 0.015 0.0299
Echinococcus multilocularis epidermal growth factor receptor 0.0295 0.1797 0.1792
Echinococcus granulosus single minded 2 0.0035 0.0137 0.0265
Leishmania major cathepsin L-like protease 0.0062 0.031 0.0617
Schistosoma mansoni hypothetical protein 0.007 0.036 0.0723
Leishmania major beta tubulin 0.0787 0.4937 1
Trichomonas vaginalis tubulin gamma chain, putative 0.0467 0.2894 0.5857
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0044
Loa Loa (eye worm) hypothetical protein 0.0041 0.0176 0.0351
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0107 0.0204
Echinococcus granulosus roundabout 2 0.0029 0.0098 0.0187
Plasmodium falciparum glutathione reductase 0.0046 0.0207 0.0392
Loa Loa (eye worm) hypothetical protein 0.0037 0.015 0.0299
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0196 0.039
Schistosoma mansoni nuclear hormone receptor 0.0041 0.0176 0.0349
Schistosoma mansoni organic anion transporter 0.0054 0.026 0.0521
Echinococcus granulosus agrin 0.0037 0.015 0.0291
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.006 0.0122
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.031 0.0617
Schistosoma mansoni follistatin 0.0037 0.015 0.0297
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0207 0.0413
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0214 0.1281 0.2591
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0214 0.1281 0.2591
Brugia malayi nuclear hormone receptor family member nhr-6 0.0041 0.0176 0.0351
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.0143 0.0283
Onchocerca volvulus 0.0041 0.0176 0.1118
Brugia malayi Nuclear hormone receptor-like 1 0.0087 0.0471 0.0948
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.0176 0.0169
Loa Loa (eye worm) hypothetical protein 0.0041 0.0176 0.0351
Brugia malayi Patched family protein 0.0018 0.0024 0.0044
Onchocerca volvulus 0.0162 0.0947 0.6543
Echinococcus granulosus tyrosine kinase 0.004 0.0171 0.0334
Loa Loa (eye worm) hypothetical protein 0.0218 0.1306 0.2642
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.031 0.0622
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0207 0.042
Mycobacterium ulcerans cell division protein FtsZ 0.0202 0.12 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0017 0.0021
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0046 0.0203 0.167
Echinococcus multilocularis transfer RNA-Lys 0.0035 0.0137 0.0131
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0054 0.026 0.0522
Mycobacterium tuberculosis Cell division protein FtsZ 0.0202 0.12 0.2822
Brugia malayi Myosin head containing protein 0.0018 0.0024 0.0044
Loa Loa (eye worm) hypothetical protein 0.0289 0.1757 0.3554
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.1514 0.3057
Onchocerca volvulus Bile acid receptor homolog 0.0087 0.0471 0.3193
Trypanosoma brucei alpha tubulin 0.0585 0.3651 0.7392
Echinococcus multilocularis carbonic anhydrase 0.0101 0.0555 0.0549
Leishmania major eukaryotic initiation factor 4a, putative 0.0024 0.0065 0.0119
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.007 0.036 0.0354
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0196 0.019
Leishmania major beta tubulin 0.0787 0.4937 1
Trypanosoma brucei trypanothione reductase 0.0046 0.0207 0.0408
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0023
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.031 0.0617
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0024 0.0065 0.0119
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0092 0.018
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0024 0.0065 0.0119
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.001 0.0016
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0585 0.3651 0.7392
Echinococcus multilocularis nuclear receptor nhr 48 0.0041 0.0176 0.0169
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.031 0.0622
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0193 0.0378
Brugia malayi MH2 domain containing protein 0.0024 0.0065 0.0126
Toxoplasma gondii beta-tubulin, putative 0.0787 0.4937 1
Brugia malayi Nuclear hormone receptor-like 1 0.0046 0.0207 0.0415
Brugia malayi Patched related family protein 10 0.0018 0.0024 0.0044
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0105 0.0586 0.1182
Brugia malayi steroid hormone receptor 0.0087 0.0471 0.0948
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0018 0.003 0.0054
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0047 0.0212 0.0206
Leishmania major beta tubulin 0.0787 0.4937 1
Brugia malayi hypothetical protein 0.0046 0.0207 0.0415
Loa Loa (eye worm) tubulin beta-1 chain 0.0787 0.4937 1
Echinococcus multilocularis tyrosine protein kinase Abl 0.0095 0.0522 0.0516
Schistosoma mansoni tubulin subunit beta 0.0202 0.12 0.2426
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0087 0.0471 0.0948
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0062 0.0306 0.0613
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0015 0.0023
Brugia malayi hypothetical protein 0.0063 0.0318 0.0639
Brugia malayi Thioredoxin reductase 0.0046 0.0207 0.0415
Schistosoma mansoni smad1 5 8 and 0.0024 0.0065 0.0124
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0207 0.0415
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0064 0.0116
Echinococcus multilocularis tyrosine protein kinase HCK 0.0034 0.0129 0.0122
Echinococcus multilocularis tubulin alpha chain 0.0585 0.3651 0.3647
Echinococcus multilocularis Niemann Pick C1 protein 0.0289 0.1757 0.1751
Onchocerca volvulus 0.0054 0.026 0.1713
Trypanosoma cruzi beta tubulin, putative 0.0787 0.4937 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.007 0.036 0.0717
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0143 0.0277
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0056 0.027 0.0535
Loa Loa (eye worm) hypothetical protein 0.0152 0.0882 0.1782
Onchocerca volvulus Protein patched homolog 0.0018 0.0024 0.0052
Loa Loa (eye worm) hypothetical protein 0.002 0.0043 0.0082
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0102 0.0562 0.1126
Brugia malayi ecdysteroid receptor 0.0087 0.0471 0.0948
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0062 0.0306 0.0607
Echinococcus granulosus smad 0.0024 0.0065 0.0118
Loa Loa (eye worm) hypothetical protein 0.0028 0.0091 0.0179
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0121 0.0232
Schistosoma mansoni alpha tubulin 0.0585 0.3651 0.7393
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0062 0.0306 0.03
Brugia malayi Integrin beta pat-3 precursor 0.0306 0.1867 0.3777
Leishmania major cathepsin L-like protease 0.0016 0.0017 0.0021
Brugia malayi Tubulin alpha-2 chain 0.0585 0.3651 0.7394
Brugia malayi Smad1 0.0024 0.0065 0.0126
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.016 0.0936 0.1885
Brugia malayi AMP-binding enzyme family protein 0.0023 0.006 0.0117
Giardia lamblia Epsilon tubulin 0.0228 0.1366 0.2746
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0062 0.0306 0.0613
Leishmania major cathepsin L-like protease 0.0016 0.0017 0.0021
Loa Loa (eye worm) hypothetical protein 0.0087 0.0471 0.0948
Loa Loa (eye worm) hypothetical protein 0.0023 0.006 0.0117
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0024 0.0065 0.0125
Schistosoma mansoni hypothetical protein 0.04 0.2464 0.4988
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0046 0.0207 0.0413
Schistosoma mansoni smad1 5 8 and 0.0024 0.0065 0.0124
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0044 0.0194 0.0188
Loa Loa (eye worm) phosphatidylinositol 3 0.0044 0.0193 0.0386
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0037 0.015 0.0299
Brugia malayi MH1 domain containing protein 0.0024 0.0065 0.0126
Echinococcus granulosus tubulin alpha 0.0441 0.2726 0.5515
Loa Loa (eye worm) beta-lactamase 0.0105 0.0586 0.1182
Trypanosoma brucei beta tubulin 0.0787 0.4937 1
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0239 0.1438 0.2903
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0105 0.0586 0.1181
Echinococcus granulosus tyrosine protein kinase Src64B 0.0047 0.0212 0.0417
Echinococcus granulosus peroxisome assembly protein 26 0.0585 0.3651 0.7392
Loa Loa (eye worm) hypothetical protein 0.0087 0.0471 0.0948
Entamoeba histolytica tubulin alpha chain, putative 0.0585 0.3651 0.7395
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.006 0.0109
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0015 0.0017
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.0143 0.0283
Echinococcus granulosus integrin alpha 3 0.0115 0.0644 0.1293
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.006 0.0385
Onchocerca volvulus 0.0018 0.0024 0.0052
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0064 0.0116
Toxoplasma gondii hypothetical protein 0.0018 0.0024 0.0042
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0062 0.0306 0.03
Echinococcus granulosus mothers against decapentaplegic 5 0.0024 0.0065 0.0118
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0017 0.0021
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.0143 0.0261
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0024 0.0065 0.0059
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.102 0.2055
Loa Loa (eye worm) hypothetical protein 0.0037 0.015 0.0299
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0202 0.12 0.2421
Loa Loa (eye worm) hypothetical protein 0.0041 0.0176 0.0351
Loa Loa (eye worm) TK/INSR protein kinase 0.0097 0.0531 0.1071
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0044 0.0193 0.0186
Echinococcus granulosus cpg binding protein 0.003 0.0102 0.0193
Loa Loa (eye worm) BEN-1 protein 0.0787 0.4937 1
Echinococcus granulosus transcription factor Dp 1 0.0037 0.0151 0.0293
Loa Loa (eye worm) hypothetical protein 0.0023 0.0061 0.0118
Echinococcus multilocularis ecdysone induced protein 78C 0.0087 0.0471 0.0464
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0024 0.0065 0.0119
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0041 0.0176 0.0169
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0041 0.0176 0.0349
Trichomonas vaginalis tubulin, putative 0.0787 0.4937 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0193 0.0378
Echinococcus multilocularis beta LACTamase domain containing family member 0.0105 0.0586 0.058
Schistosoma mansoni thyroid hormone receptor 0.021 0.1256 0.2539
Mycobacterium tuberculosis Probable esterase LipL 0.0105 0.0586 0.136
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0044
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0289 0.1757 0.3558
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0041 0.0176 0.0343
Toxoplasma gondii thioredoxin reductase 0.0046 0.0207 0.0413
Schistosoma mansoni tyrosine kinase 0.0097 0.0531 0.1069
Leishmania major alpha tubulin 0.0585 0.3651 0.7392
Echinococcus granulosus eukaryotic initiation factor 4A 0.0024 0.0065 0.0119
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0015 0.0023
Loa Loa (eye worm) hypothetical protein 0.0054 0.026 0.0522
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0155 0.0284
Plasmodium vivax vivapain-2 0.0016 0.0017 0.0034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0064 0.0116
Schistosoma mansoni tubulin subunit beta 0.0787 0.4937 1
Brugia malayi hypothetical protein 0.0231 0.1388 0.2807
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0105 0.0585 0.4606
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0046 0.0207 0.0201
Trypanosoma brucei epsilon tubulin 0.0441 0.2726 0.5515
Toxoplasma gondii beta-1 tubulin, putative 0.0787 0.4937 1
Brugia malayi Cell division protein ftsZ 0.0202 0.12 0.2427
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0193 0.0378
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0016 0.0017 0.0005
Echinococcus granulosus Smad4 0.0024 0.0065 0.0118
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0124 0.0704 0.1421
Loa Loa (eye worm) alpha-tubulin 0.0585 0.3651 0.7394
Brugia malayi hypothetical protein 0.0046 0.0209 0.0419
Leishmania major beta tubulin 0.0787 0.4937 1
Echinococcus multilocularis geminin 0.0661 0.4133 0.413
Brugia malayi Integrin alpha pat-2 precursor 0.0149 0.0867 0.1751
Echinococcus multilocularis tubulin alpha chain 0.0585 0.3651 0.3647
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0196 0.0384
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0044
Brugia malayi Immunoglobulin I-set domain containing protein 0.0105 0.058 0.1171
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0094 0.0178
Leishmania major eukaryotic initiation factor 4a, putative 0.0024 0.0065 0.0119
Loa Loa (eye worm) RecQ helicase 0.004 0.0169 0.0338
Brugia malayi beta-lactamase family protein 0.0105 0.0586 0.1182
Onchocerca volvulus 0.0048 0.0221 0.1436
Leishmania major beta tubulin 0.0787 0.4937 1
Echinococcus granulosus nuclear receptor nhr 48 0.0041 0.0176 0.0343
Trypanosoma cruzi tubulin gamma chain 0.0467 0.2894 0.5859
Trypanosoma brucei beta tubulin 0.0787 0.4937 1
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0041 0.0177 0.0358
Schistosoma mansoni aryl hydrocarbon receptor 0.0048 0.0216 0.0431
Echinococcus granulosus twitchin 0.0023 0.0062 0.0112
Schistosoma mansoni tyrosine kinase 0.0207 0.1234 0.2493
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0028 0.0091 0.0085
Trichomonas vaginalis esterase, putative 0.0105 0.0586 0.1175
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0044 0.0193 0.0378
Leishmania major alpha tubulin 0.0585 0.3651 0.7392
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0121 0.0238
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0017 0.001
Plasmodium falciparum tubulin epsilon chain, putative 0.0467 0.2892 0.5845
Brugia malayi Patched family protein 0.0018 0.0024 0.0044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.008 0.0149
Plasmodium falciparum tubulin beta chain 0.0787 0.4937 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0196 0.019
Echinococcus multilocularis Tubulin beta 2C chain 0.0787 0.4937 0.4934
Leishmania major cathepsin L-like protease 0.0016 0.0017 0.0021
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0196 0.039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0135 0.0262
Echinococcus granulosus sterol regulatory element binding protein 0.0124 0.0704 0.1414
Leishmania major cathepsin L-like protease 0.0016 0.0017 0.0021
Loa Loa (eye worm) hypothetical protein 0.0026 0.0081 0.0158
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0046 0.0203 0.0449
Schistosoma mansoni tyrosine kinase 0.0155 0.0902 0.1821
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.006 0.0122
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0044
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0274 0.0548
Schistosoma mansoni tyrosine kinase 0.016 0.0936 0.189
Loa Loa (eye worm) hypothetical protein 0.0384 0.2363 0.4784
Echinococcus granulosus carbonic anhydrase II 0.0214 0.1281 0.2585
Brugia malayi Patched family protein 0.0018 0.0024 0.0044
Loa Loa (eye worm) hypothetical protein 0.0036 0.0143 0.0285
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0963 0.194
Toxoplasma gondii alpha-tubulin I, putative 0.0585 0.3651 0.7393
Loa Loa (eye worm) hypothetical protein 0.0026 0.0081 0.0158
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0023
Echinococcus multilocularis Tubulin alpha 1 chain 0.0585 0.3651 0.3647
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0024 0.0065 0.0124
Leishmania major beta tubulin 0.0787 0.4937 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0017 0.0021
Loa Loa (eye worm) isocitrate dehydrogenase 0.0062 0.0306 0.0615
Trichomonas vaginalis penicillin-binding protein, putative 0.0105 0.0586 0.1175
Brugia malayi hypothetical protein 0.0018 0.0024 0.0044
Brugia malayi Patched family protein 0.0018 0.0024 0.0044
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0117 0.0661 0.1537
Schistosoma mansoni tubulin subunit beta 0.0787 0.4937 1
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0037 0.015 0.0299
Loa Loa (eye worm) hypothetical protein 0.0017 0.0023 0.0041
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0963 0.194
Entamoeba histolytica protein kinase, putative 0.0034 0.0129 0.0261
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0047 0.0212 0.0206
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0347 0.2126 0.4298
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0037 0.015 0.0299
Echinococcus multilocularis carbonic anhydrase II 0.0214 0.1281 0.1275
Brugia malayi hypothetical protein 0.0159 0.0931 0.1881
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0121 0.0232
Echinococcus multilocularis cysteine protease 0.0016 0.0017 0.001
Leishmania major carbonic anhydrase-like protein 0.0214 0.1281 0.2585
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0044
Echinococcus granulosus neuropeptide receptor A26 0.046 0.2852 0.5771
Loa Loa (eye worm) hypothetical protein 0.0026 0.0081 0.0158
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0091 0.0179
Brugia malayi Steroid receptor seven-up type 2 0.0087 0.0471 0.0948
Echinococcus granulosus tubulin alpha 3 chain 0.0585 0.3651 0.7392
Schistosoma mansoni alpha tubulin 0.0585 0.3651 0.7393
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.031 0.0617
Echinococcus multilocularis hypothetical protein 0.0585 0.3651 0.3647
Schistosoma mansoni hypothetical protein 0.0015 0.001 0.0014
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0087 0.0471 0.0464
Plasmodium falciparum cysteine proteinase falcipain 3 0.0016 0.0017 0.0005
Schistosoma mansoni DNA helicase recq5 0.0028 0.0091 0.0177
Brugia malayi Patched family protein 0.0018 0.0024 0.0044
Brugia malayi hypothetical protein 0.0018 0.0024 0.0044
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.001 0.0004
Mycobacterium tuberculosis Probable lipase LipD 0.0105 0.0586 0.136
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0113 0.0634 0.128
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0037 0.015 0.0299
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0041 0.0177 0.0351
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0024 0.0065 0.0125
Mycobacterium tuberculosis Probable dehydrogenase 0.0105 0.0585 0.1358
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.0276 0.0552
Loa Loa (eye worm) hypothetical protein 0.002 0.0043 0.0082
Plasmodium falciparum eukaryotic initiation factor 4A 0.0024 0.0065 0.0102
Entamoeba histolytica hypothetical protein 0.007 0.036 0.0729
Echinococcus granulosus carbonic anhydrase 0.0101 0.0555 0.1113
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0087 0.0471 0.0947
Echinococcus granulosus tyrosine protein kinase Src42A 0.0047 0.0212 0.0417
Echinococcus granulosus tyrosine protein kinase Blk 0.004 0.0171 0.0334
Giardia lamblia GTOR 0.0044 0.0193 0.0362
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0041 0.0176 0.0169
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.031 0.0617
Echinococcus granulosus tubulin subunit beta 0.0787 0.4937 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0176 0.0351
Schistosoma mansoni Neurotrimin precursor (hNT) 0.002 0.0043 0.008
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0017 0.0005
Echinococcus granulosus TGF beta signal transducer SmadC 0.0024 0.0065 0.0118
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0214 0.1281 0.2591
Loa Loa (eye worm) cysteine protease 0.0016 0.0017 0.0029
Brugia malayi intermediate filament protein 0.0026 0.0081 0.0158
Loa Loa (eye worm) hypothetical protein 0.0017 0.0023 0.0041
Trichomonas vaginalis tubulin alpha chain, putative 0.0239 0.1438 0.2903
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0064 0.0324 0.0318
Loa Loa (eye worm) hypothetical protein 0.0023 0.0061 0.0118
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0002
Echinococcus granulosus epidermal growth factor receptor 0.0295 0.1797 0.3632
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0214 0.1281 0.2589
Mycobacterium ulcerans hypothetical protein 0.0105 0.0586 0.4819
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0087 0.0471 0.0948
Loa Loa (eye worm) hypothetical protein 0.0026 0.0082 0.016
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0044
Loa Loa (eye worm) hypothetical protein 0.0041 0.0176 0.0351
Loa Loa (eye worm) hypothetical protein 0.0054 0.026 0.0522
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0028 0.0091 0.0172
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0141 0.0811 0.0805
Leishmania major gamma-tubulin 0.0467 0.2894 0.5857
Loa Loa (eye worm) hypothetical protein 0.0023 0.006 0.0117
Echinococcus granulosus fibroblast growth factor receptor 4 0.0102 0.0562 0.1126
Toxoplasma gondii patched family protein 0.0018 0.0024 0.0042
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0081 0.0158
Loa Loa (eye worm) hypothetical protein 0.0041 0.0176 0.0351
Echinococcus multilocularis bloom syndrome protein 0.004 0.0169 0.0163
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0044 0.0193 0.0378
Trypanosoma brucei hypothetical protein, conserved 0.0046 0.0203 0.0399
Leishmania major alpha tubulin 0.0585 0.3651 0.7392
Mycobacterium tuberculosis Probable reductase 0.0105 0.0585 0.1358
Onchocerca volvulus Putative organic anion transporter 0.0054 0.026 0.1713
Echinococcus multilocularis basement membrane specific heparan sulfate 0.002 0.0043 0.0037
Echinococcus granulosus tubulin alpha chain 0.0585 0.3651 0.7392
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0087 0.0471 0.0941
Toxoplasma gondii patched family protein 0.0018 0.0024 0.0042
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0044
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0017 0.0021
Onchocerca volvulus 0.0023 0.006 0.0306
Brugia malayi CHE-14 protein 0.0124 0.0704 0.1421
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0143 0.0137
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0064 0.0324 0.0645
Loa Loa (eye worm) tubulin alpha-2 chain 0.0585 0.3651 0.7394
Toxoplasma gondii tubulin, putative 0.0026 0.0079 0.0152
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0015 0.0017
Schistosoma mansoni hypothetical protein 0.0119 0.0675 0.1362
Schistosoma mansoni tyrosine kinase 0.016 0.0936 0.189
Echinococcus multilocularis sterol regulatory element binding protein 0.0124 0.0704 0.0698
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.006 0.0385
Loa Loa (eye worm) acetyltransferase 0.0141 0.0811 0.1638
Brugia malayi Tubulin alpha chain 0.0202 0.12 0.2427
Leishmania major cathepsin L-like protease 0.0016 0.0017 0.0021
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0044
Trichomonas vaginalis D-aminoacylase, putative 0.0105 0.0586 0.1175
Loa Loa (eye worm) MH2 domain-containing protein 0.035 0.2149 0.4349
Loa Loa (eye worm) hypothetical protein 0.0023 0.0062 0.012
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0046 0.0203 1
Leishmania major hypothetical protein, conserved 0.0105 0.0586 0.1175
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0105 0.0585 0.1358
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0017 0.0005
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0105 0.0585 0.1358
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.006 0.0109
Brugia malayi tubulin alpha chain - mouse 0.0585 0.3651 0.7394
Brugia malayi acetyltransferase, GNAT family protein 0.0141 0.0811 0.1638
Schistosoma mansoni tubulin subunit alpha 0.0585 0.3651 0.7393
Brugia malayi Patched family protein 0.0018 0.0024 0.0044
Echinococcus multilocularis Tubulin beta 2C chain 0.0787 0.4937 0.4934
Loa Loa (eye worm) hypothetical protein 0.0105 0.0586 0.1182
Echinococcus multilocularis Tubulin alpha 1 chain 0.0585 0.3651 0.3647
Echinococcus granulosus L aminoadipate semialdehyde 0.0162 0.0947 0.1907
Loa Loa (eye worm) steroid hormone receptor 0.0087 0.0471 0.0948
Mycobacterium leprae conserved hypothetical protein 0.0046 0.0203 0.1254
Schistosoma mansoni hypothetical protein 0.0661 0.4133 0.837
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.004 0.0171 0.0334
Loa Loa (eye worm) hypothetical protein 0.0087 0.0471 0.0948
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0202 0.12 1
Trichomonas vaginalis tubulin alpha chain, putative 0.0239 0.1438 0.2903
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0078 0.0146
Schistosoma mansoni carbonic anhydrase-related 0.0101 0.0555 0.1118
Schistosoma mansoni nuclear receptor 0.0041 0.0176 0.0349
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0023
Loa Loa (eye worm) hypothetical protein 0.0048 0.0222 0.0444
Trypanosoma brucei alpha tubulin, putative 0.0239 0.1438 0.2903
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0087 0.0471 0.0464
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0047 0.0212 0.0206
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0044 0.0193 0.0386
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0006 0.0008
Trypanosoma cruzi epsilon tubulin, putative 0.0467 0.2892 0.5854
Echinococcus multilocularis follistatin 0.0037 0.015 0.0144
Leishmania major beta tubulin 0.0787 0.4937 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0117 0.0233
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0047 0.0212 0.0206
Onchocerca volvulus 0.0054 0.026 0.1713
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0047 0.0212 0.0417
Echinococcus multilocularis tubulin beta 1 chain 0.0787 0.4937 0.4934
Mycobacterium ulcerans beta-lactamase 0.0105 0.0586 0.4819
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0963 0.194
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0046 0.0207 0.0413
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.0196 0.0392
Loa Loa (eye worm) hypothetical protein 0.0124 0.0704 0.1421
Echinococcus multilocularis Tubulin beta 2C chain 0.0787 0.4937 0.4934
Trichomonas vaginalis tubulin beta chain, putative 0.0585 0.3651 0.7392
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0087 0.0471 0.0948
Trypanosoma cruzi PAB1-binding protein , putative 0.0098 0.054 0.1088
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0087 0.0471 0.0464
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0123 0.0698 0.0692
Trypanosoma cruzi zeta tubulin, putative 0.0474 0.2941 0.5953
Echinococcus granulosus tubulin alpha 3 chain 0.0585 0.3651 0.7392
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.001 0.0004
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0251 0.1514 0.3062
Trichomonas vaginalis bromodomain-containing protein, putative 0.0041 0.0177 0.0345
Trypanosoma cruzi hypothetical protein, conserved 0.0105 0.0586 0.1181
Brugia malayi beta-tubulin, identical 0.0787 0.4937 1
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0162 0.0947 0.1912
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0017 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0121 0.0232
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0087 0.0471 0.0948
Trypanosoma brucei beta tubulin 0.0441 0.2726 0.5515
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.001 0.0008
Schistosoma mansoni agrin 0.0037 0.015 0.0297
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0024 0.0065 0.0059
Brugia malayi Furin-like cysteine rich region family protein 0.0295 0.1797 0.3637
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0044
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0064 0.0324 0.0645
Schistosoma mansoni thyroid hormone receptor 0.021 0.1256 0.2539
Loa Loa (eye worm) MH2 domain-containing protein 0.0024 0.0065 0.0126
Echinococcus granulosus tubulin epsilon chain 0.0467 0.2892 0.5852
Trypanosoma brucei PAB1-binding protein , putative 0.0098 0.054 0.1083
Brugia malayi Patched protein homolog 1 0.0018 0.0024 0.0044
Trichomonas vaginalis tubulin epsilon chain, putative 0.0202 0.12 0.2421
Trichomonas vaginalis penicillin-binding protein, putative 0.0105 0.0586 0.1175
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0044 0.0193 0.0378
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0046 0.0203 0.1591
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0037 0.015 0.0299
Echinococcus multilocularis dnaJ subfamily B 0.04 0.2464 0.246
Loa Loa (eye worm) hypothetical protein 0.0048 0.0221 0.0443
Brugia malayi secreted modular calcium-binding protein 1 0.0037 0.015 0.0299
Leishmania major delta tubulin, putative 0.0365 0.2241 0.4532
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0062 0.0306 0.0607
Schistosoma mansoni tyrosine kinase 0.0155 0.0902 0.1821
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0087 0.0471 0.0947
Leishmania major beta tubulin 0.0787 0.4937 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0087 0.0471 0.0948
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0135 0.0262
Leishmania major alpha tubulin 0.0585 0.3651 0.7392
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0028 0.0091 0.0155
Schistosoma mansoni zinc finger protein 0.0041 0.0176 0.0349
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.006 0.0109
Brugia malayi Isocitrate dehydrogenase 0.0062 0.0306 0.0615
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.008 0.0149
Giardia lamblia Sgs1 DNA helicase, putative 0.0028 0.0091 0.0155
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0017 0.0005
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0038 0.0153 0.0281
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0028 0.0091 0.0179
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0015 0.0023
Schistosoma mansoni tubulin subunit alpha 0.0585 0.3651 0.7393
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0101 0.0555 0.112
Brugia malayi sodium-independent organic anion transporter family protein 0.0054 0.026 0.0522
Echinococcus granulosus c src tyrosine kinase 0.0018 0.003 0.0048
Trypanosoma brucei carbonic anhydrase-like protein 0.0214 0.1281 0.2585
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0035 0.0137 0.013
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0062 0.0306 0.0693
Loa Loa (eye worm) hypothetical protein 0.0046 0.0207 0.0415
Trichomonas vaginalis tubulin epsilon chain, putative 0.0787 0.4937 1
Schistosoma mansoni RAR-like nuclear receptor 0.0087 0.0471 0.0947
Echinococcus granulosus bloom syndrome protein 0.004 0.0169 0.033
Trichomonas vaginalis conserved hypothetical protein 0.0124 0.0704 0.1414
Onchocerca volvulus 0.0087 0.0471 0.3193
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0516 0.3211 0.3206
Brugia malayi nuclear receptor NHR-88 0.0087 0.0471 0.0948
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0155 0.0284
Trichomonas vaginalis glucosylceramidase, putative 0.0251 0.1514 0.3057
Trichomonas vaginalis tubulin alpha chain, putative 0.0787 0.4937 1
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0047 0.0212 0.0206
Echinococcus multilocularis tumor protein p63 0.033 0.2021 0.2016
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.0963 0.194
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0046 0.0207 0.0415
Echinococcus multilocularis neuropeptide receptor A26 0.046 0.2852 0.2847
Leishmania major alpha tubulin 0.0585 0.3651 0.7392
Echinococcus multilocularis agrin 0.0037 0.015 0.0144
Echinococcus granulosus tyrosine protein kinase Fyn 0.0047 0.0212 0.0417
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0017 0.0021
Entamoeba histolytica tubulin alpha-1 chain 0.0585 0.3651 0.7395
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0062 0.0306 0.03
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0046 0.0203 0.0412
Plasmodium vivax patched family protein, putative 0.0018 0.0024 0.0049
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0028 0.0091 0.0172
Echinococcus multilocularis epidermal growth factor receptor 0.016 0.0936 0.093
Brugia malayi Papain family cysteine protease containing protein 0.0016 0.0017 0.0029
Loa Loa (eye worm) hypothetical protein 0.0117 0.0662 0.1335
Echinococcus multilocularis integrin alpha ps 0.0032 0.0117 0.0111
Brugia malayi hypothetical protein 0.0054 0.026 0.0522
Leishmania major beta tubulin 0.0787 0.4937 1
Loa Loa (eye worm) patched family protein 0.0018 0.0024 0.0044
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0015 0.0023
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0024 0.0065 0.0132
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0017 0.001
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.0143 0.0285
Schistosoma mansoni tubulin subunit beta 0.0787 0.4937 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.0047 0.0212 0.0417
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.0143 0.0137
Plasmodium vivax tubulin beta chain, putative 0.0787 0.4937 1
Plasmodium falciparum alpha tubulin 1 0.0585 0.3651 0.7387
Schistosoma mansoni cpg binding protein 0.003 0.0102 0.0199
Echinococcus multilocularis integrin beta 2 0.0227 0.136 0.1355
Loa Loa (eye worm) hypothetical protein 0.0105 0.0586 0.1182
Trypanosoma brucei beta tubulin 0.0787 0.4937 1
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0101 0.0555 0.112
Echinococcus multilocularis isocitrate dehydrogenase 0.0062 0.0306 0.03
Loa Loa (eye worm) hypothetical protein 0.0041 0.0176 0.0351
Plasmodium falciparum lipid/sterol:H+ symporter 0.0018 0.0024 0.002
Trichomonas vaginalis tubulin gamma chain, putative 0.0467 0.2892 0.5852
Echinococcus granulosus tyrosine protein kinase Fyn 0.0047 0.0212 0.0417
Loa Loa (eye worm) hypothetical protein 0.0017 0.0023 0.0041
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0044
Echinococcus multilocularis tyrosine protein kinase Fyn 0.004 0.0171 0.0165
Schistosoma mansoni nuclear receptor nhr-48 0.0041 0.0176 0.0349

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 68 uM Inhibition of human recombinant MMP2 expressed in mouse myeloma cells ChEMBL. 17276072
IC50 (binding) = 68 uM Inhibition of human recombinant MMP2 expressed in mouse myeloma cells ChEMBL. 17276072
IC50 (binding) = 141 uM Inhibition of human recombinant MMP9 expressed in mouse myeloma cells ChEMBL. 17276072
IC50 (binding) = 141 uM Inhibition of human recombinant MMP9 expressed in mouse myeloma cells ChEMBL. 17276072
Ki (binding) = 4.7 uM Inhibition of human recombinant carbonic anhydrase 2 by CO2 hydration method ChEMBL. 17276072
Ki (binding) = 4.7 uM Inhibition of human recombinant carbonic anhydrase 2 by CO2 hydration method ChEMBL. 17276072
Ki (binding) = 9.2 uM Inhibition of human recombinant carbonic anhydrase 9 by CO2 hydration method ChEMBL. 17276072
Ki (binding) = 9.2 uM Inhibition of human recombinant carbonic anhydrase 9 by CO2 hydration method ChEMBL. 17276072
Ki (binding) = 9.8 uM Inhibition of human recombinant carbonic anhydrase 1 by CO2 hydration method ChEMBL. 17276072
Ki (binding) = 9.8 uM Inhibition of human recombinant carbonic anhydrase 1 by CO2 hydration method ChEMBL. 17276072

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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