Detailed information for compound 459259

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 421.471 | Formula: C19H29N6O5
  • H donors: 5 H acceptors: 7 LogP: 0.1 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2NC1CC(C)(C)N(C(C1)(C)C)[O]
  • InChi: 1S/C19H29N6O5/c1-18(2)5-10(6-19(3,4)25(18)29)23-15-12-16(21-8-20-15)24(9-22-12)17-14(28)13(27)11(7-26)30-17/h8-11,13-14,17,26-28H,5-7H2,1-4H3,(H,20,21,23)/t11-,13-,14-,17-/m1/s1
  • InChiKey: ZTWZYJHYVXEYCT-LSCFUAHRSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens adenosine A1 receptor Starlite/ChEMBL References
Homo sapiens adenosine A2b receptor Starlite/ChEMBL References
Homo sapiens adenosine A3 receptor Starlite/ChEMBL References
Homo sapiens adenosine A2a receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi follicle stimulating hormone receptor adenosine A2a receptor 412 aa 336 aa 22.3 %
Brugia malayi hypothetical protein adenosine A1 receptor 326 aa 305 aa 21.0 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0149 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0166 0.0042 0.0041
Brugia malayi Receptor family ligand binding region containing protein 0.0149 0.0012 0.0011
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0625 0.0847 0.0847
Trichomonas vaginalis CMGC family protein kinase 0.0321 0.0314 0.15
Schistosoma mansoni protein kinase 0.0149 0.0012 0.0006
Loa Loa (eye worm) P21-Rho-binding domain-containing protein 0.0145 0.0006 0.0005
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0383 0.0422 0.0417
Giardia lamblia Kinase, CAMK CAMKL 0.0264 0.0214 0.102
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0312 0.0298 0.0297
Echinococcus granulosus tyrosine protein kinase otk 0.0152 0.0019 0.0018
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0455 0.0548 0.0547
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0625 0.0847 0.0847
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0169 0.0048 0.0047
Trichomonas vaginalis CAMK family protein kinase 0.0169 0.0048 0.0232
Schistosoma mansoni serine/threonine-protein kinase 0.0748 0.1061 0.1056
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0625 0.0847 0.0847
Loa Loa (eye worm) hypothetical protein 0.0481 0.0593 0.0592
Brugia malayi Protein kinase domain containing protein 0.0929 0.1379 0.1378
Echinococcus multilocularis CDC7 cell division cycle 7 0.0173 0.0055 0.0055
Plasmodium falciparum protein kinase, putative 0.026 0.0206 0.205
Trichomonas vaginalis CK1 family protein kinase 0.0309 0.0293 0.14
Giardia lamblia Kinase, CMGC CLK 0.0243 0.0178 0.0839
Entamoeba histolytica protein kinase, putative 0.0287 0.0254 0.1214
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0571 0.0752 0.0751
Toxoplasma gondii AGC kinase 0.1307 0.204 1
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0903 0.1332 0.1332
Echinococcus multilocularis tyrosine kinase 0.0278 0.0238 0.0237
Loa Loa (eye worm) TK/FER protein kinase 0.0149 0.0012 0.0011
Echinococcus granulosus lachesin 0.0152 0.0019 0.0018
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0717 0.1007 0.1007
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0149 0.0012 0.0011
Echinococcus multilocularis neuroglian 0.0405 0.0461 0.046
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0234 0.0162 0.0156
Echinococcus multilocularis lachesin 0.0152 0.0019 0.0018
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0252 0.0193 0.0192
Onchocerca volvulus 0.0173 0.0055 0.0148
Entamoeba histolytica protein kinase, putative 0.0149 0.0012 0.0057
Echinococcus granulosus roundabout 2 0.0179 0.0066 0.0065
Brugia malayi Protein kinase domain containing protein 0.0712 0.0998 0.0997
Brugia malayi Kinase associated domain 1 family protein 0.0391 0.0436 0.0435
Trichomonas vaginalis CMGC family protein kinase 0.0455 0.0548 0.2618
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0318 0.0309 0.0309
Giardia lamblia Aurora kinase 0.0632 0.0858 0.4276
Brugia malayi Protein kinase domain containing protein 0.052 0.0663 0.0662
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0296 0.0269 0.0269
Entamoeba histolytica casein kinase 1, putative 0.0309 0.0293 0.14
Echinococcus granulosus tyrosine protein kinase Blk 0.052 0.0662 0.0662
Brugia malayi protein kinase C3,putative 0.0717 0.1008 0.1007
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0325 0.0321 0.1532
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0625 0.0847 0.0847
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0252 0.0193 0.0192
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0243 0.0178 0.0894
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0225 0.0146 0.0146
Brugia malayi putative serine/threonine kinase SADA gamma 0.0264 0.0214 0.0213
Loa Loa (eye worm) TK/FER protein kinase 0.0278 0.0238 0.0237
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0616 0.0831 0.0831
Echinococcus granulosus protein kinase 0.0149 0.0012 0.0011
Plasmodium vivax serine/threonine kinase-1, putative 0.0243 0.0178 0.1766
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.097 0.145 0.1449
Entamoeba histolytica tyrosine kinase, putative 0.0149 0.0012 0.0057
Loa Loa (eye worm) hypothetical protein 0.016 0.0031 0.003
Loa Loa (eye worm) TK/ROR protein kinase 0.0225 0.0146 0.0145
Echinococcus multilocularis protein kinase c epsilon type 0.0889 0.1309 0.1309
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0149 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0467 0.057 0.0569
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.052 0.0663 0.0662
Echinococcus granulosus dual specificity mitogen activated protein 0.0192 0.0089 0.0088
Schistosoma mansoni serine/threonine protein kinase 0.0502 0.0631 0.0625
Echinococcus multilocularis serine threonine protein kinase 0.091 0.1346 0.1346
Brugia malayi P21-Rho-binding domain containing protein 0.0145 0.0006 0.0005
Schistosoma mansoni vam6/vps39 related 0.0166 0.0042 0.0036
Schistosoma mansoni serine/threonine protein kinase 0.1319 0.2062 0.2057
Entamoeba histolytica protein kinase domain containing protein 0.0169 0.0048 0.023
Brugia malayi Fibronectin type III domain containing protein 0.0355 0.0373 0.0372
Giardia lamblia Kinase, STE STE20 0.0325 0.0321 0.1561
Loa Loa (eye worm) CAMKK/META protein kinase 0.0169 0.0048 0.0047
Trichomonas vaginalis CAMK family protein kinase 0.0264 0.0214 0.1021
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0321 0.0314 0.1578
Brugia malayi Protein kinase domain containing protein 0.0169 0.0048 0.0047
Echinococcus multilocularis casein kinase i 0.0309 0.0293 0.0293
Brugia malayi casein kinase I 0.0309 0.0293 0.0292
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0149 0.0012 0.0058
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0176 0.006 0.0059
Echinococcus granulosus protein kinase 0.0243 0.0177 0.0176
Echinococcus granulosus PAK box P21 Rho binding 0.0145 0.0006 0.0005
Echinococcus granulosus Vam6:Vps39 protein 0.0166 0.0042 0.0042
Brugia malayi RhoGAP domain containing protein 0.0182 0.007 0.0069
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0309 0.0293 0.0292
Loa Loa (eye worm) TK/KIN16 protein kinase 0.2561 0.4236 0.4236
Giardia lamblia Kinase, CMGC DYRK 0.0169 0.0048 0.0183
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.1783 0.2873 0.2872
Entamoeba histolytica protein kinase, putative 0.0632 0.0858 0.4098
Schistosoma mansoni protein kinase 0.0149 0.0012 0.0006
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Entamoeba histolytica hypothetical protein 0.0149 0.0013 0.0061
Schistosoma mansoni nephrin 0.0432 0.0508 0.0502
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0346 0.0358 0.0357
Trichomonas vaginalis conserved hypothetical protein 0.0149 0.0012 0.0057
Schistosoma mansoni serine/threonine protein kinase 0.036 0.0382 0.0376
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0039 0.0187
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0149 0.0012 0.0011
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0152 0.0019 0.0018
Brugia malayi Protein kinase domain containing protein 0.0178 0.0064 0.0063
Loa Loa (eye worm) hypothetical protein 0.0862 0.1262 0.1261
Trypanosoma brucei protein kinase, putative 0.026 0.0206 0.0986
Entamoeba histolytica protein kinase, putative 0.0305 0.0286 0.1366
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0296 0.0269 0.0268
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0321 0.0314 0.1578
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0311 0.0296 0.0295
Echinococcus multilocularis tyrosine protein kinase csk 0.0149 0.0012 0.0011
Giardia lamblia Kinase, CMGC MAPK 0.0321 0.0314 0.1527
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0039 0.0187
Entamoeba histolytica protein kinase domain containing protein 0.0149 0.0012 0.0057
Entamoeba histolytica hypothetical protein 0.0182 0.007 0.0336
Echinococcus granulosus protein kinase C gamma type 0.091 0.1346 0.1346
Brugia malayi Doublecortin family protein 0.024 0.0172 0.0171
Trichomonas vaginalis CK1 family protein kinase 0.0309 0.0293 0.14
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.1037 0.1568 0.1567
Schistosoma mansoni protein kinase 0.0243 0.0177 0.0171
Echinococcus multilocularis dual specificity 0.0169 0.0048 0.0048
Echinococcus granulosus c src tyrosine kinase 0.0383 0.0422 0.0422
Brugia malayi Protein kinase domain containing protein 0.0411 0.0472 0.0471
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Brugia malayi Protein kinase domain containing protein 0.0149 0.0012 0.0011
Brugia malayi Protein kinase domain containing protein 0.0571 0.0752 0.0751
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.036 0.0382 0.0382
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.1307 0.204 0.2039
Entamoeba histolytica protein kinase, putative 0.0256 0.0201 0.0958
Schistosoma mansoni hypothetical protein 0.0182 0.007 0.0064
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Entamoeba histolytica cysteine surface protein, putative 0.0149 0.0012 0.0057
Onchocerca volvulus 0.1208 0.1867 0.5096
Loa Loa (eye worm) TK protein kinase 0.1045 0.1582 0.1581
Giardia lamblia Kinase, AGC PKA 0.036 0.0382 0.187
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.036 0.0382 0.0382
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0039 0.0187
Schistosoma mansoni neuroglian 0.0179 0.0066 0.006
Entamoeba histolytica protein kinase, putative 0.0149 0.0012 0.0057
Trichomonas vaginalis AGC family protein kinase 0.1338 0.2094 1
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0632 0.0858 0.8517
Trichomonas vaginalis CAMK family protein kinase 0.1279 0.1991 0.9507
Trichomonas vaginalis CAMK family protein kinase 0.0264 0.0214 0.1021
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Entamoeba histolytica protein kinase, putative 0.0149 0.0012 0.0057
Echinococcus multilocularis tyrosine protein kinase csk 0.0149 0.0012 0.0011
Onchocerca volvulus 0.0554 0.0722 0.1968
Trichomonas vaginalis CAMK family protein kinase 0.0264 0.0214 0.1021
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0578 0.0764 0.3839
Entamoeba histolytica hypothetical protein 0.0149 0.0012 0.0057
Entamoeba histolytica hypothetical protein 0.0149 0.0012 0.0057
Trypanosoma cruzi polo-like protein kinase, putative 0.1279 0.1991 1
Echinococcus granulosus retinal guanylyl cyclase 2 0.0149 0.0012 0.0011
Echinococcus granulosus defective proboscis extension response 0.0328 0.0326 0.0326
Loa Loa (eye worm) hypothetical protein 0.0181 0.0069 0.0068
Loa Loa (eye worm) RGC/RGC protein kinase 0.0149 0.0012 0.0011
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0278 0.0238 0.0237
Loa Loa (eye worm) TK/FER protein kinase 0.0278 0.0238 0.0237
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0149 0.0012 0.0057
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0169 0.0048 0.023
Onchocerca volvulus 0.1319 0.2062 0.5627
Echinococcus granulosus tyrosine protein kinase Src42A 0.0376 0.0411 0.041
Schistosoma mansoni serine/threonine protein kinase 0.0701 0.0979 0.0974
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0625 0.0847 0.0847
Trichomonas vaginalis CAMK family protein kinase 0.1279 0.1991 0.9507
Loa Loa (eye worm) hypothetical protein 0.0149 0.0012 0.0011
Echinococcus granulosus tyrosine protein kinase Btk29A 0.1081 0.1644 0.1644
Trichomonas vaginalis conserved hypothetical protein 0.0149 0.0012 0.0057
Schistosoma mansoni protein kinase 0.0632 0.0858 0.0853
Entamoeba histolytica tyrosine kinase, putative 0.0149 0.0012 0.0057
Entamoeba histolytica serine/threonine protein kinase, putative 0.0264 0.0214 0.1021
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0968 0.1447 0.1447
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0554 0.0722 0.0721
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0311 0.0296 0.0296
Schistosoma mansoni tyrosine kinase 0.0968 0.1447 0.1442
Entamoeba histolytica protein kinase, putative 0.1338 0.2094 1
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Loa Loa (eye worm) hypothetical protein 0.0149 0.0012 0.0011
Trichomonas vaginalis CMGC family protein kinase 0.0508 0.0642 0.3066
Echinococcus multilocularis casein kinase I delta 0.0309 0.0293 0.0293
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Schistosoma mansoni tyrosine kinase 0.0703 0.0982 0.0977
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0574 0.0757 0.0756
Entamoeba histolytica protein kinase domain containing protein 0.0149 0.0012 0.0057
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Schistosoma mansoni growth factor receptor-bound protein 0.0234 0.0162 0.0156
Echinococcus multilocularis nervana 2 0.0606 0.0813 0.0812
Loa Loa (eye worm) hypothetical protein 0.0166 0.0042 0.0041
Schistosoma mansoni tyrosine kinase 0.0149 0.0012 0.0006
Schistosoma mansoni serine/threonine protein kinase 0.0318 0.0309 0.0304
Loa Loa (eye worm) RGC/RGC protein kinase 0.0149 0.0012 0.0011
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0169 0.0048 0.0236
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0612 0.0824 0.3935
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.036 0.0382 0.0382
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0748 0.1061 0.533
Loa Loa (eye worm) TK/Met protein kinase 0.0149 0.0012 0.0011
Entamoeba histolytica tyrosine kinase, putative 0.0149 0.0012 0.0057
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0238 0.0168 0.0167
Echinococcus granulosus casein kinase I delta 0.0309 0.0293 0.0293
Loa Loa (eye worm) hypothetical protein 0.0152 0.0019 0.0018
Leishmania major protein kinase, putative 0.0632 0.0858 0.4311
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0717 0.1007 1
Schistosoma mansoni tyrosine kinase 0.1813 0.2926 0.2922
Brugia malayi Protein kinase domain containing protein 0.0173 0.0055 0.0054
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0782 0.1121 0.1121
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.026 0.0206 0.1012
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0325 0.0321 0.1612
Echinococcus multilocularis activated cdc42 kinase 1 0.033 0.033 0.033
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Entamoeba histolytica protein kinase domain containing protein 0.026 0.0206 0.0986
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0296 0.0269 0.0269
Schistosoma mansoni serine/threonine protein kinase 0.0707 0.099 0.0984
Brugia malayi STE20-like kinase MST 0.1037 0.1568 0.1567
Echinococcus multilocularis PAK box P21 Rho binding 0.0145 0.0006 0.0005
Toxoplasma gondii CMGC kinase, CK2 family 0.0455 0.0548 0.2687
Echinococcus multilocularis natriuretic peptide receptor 1 0.0149 0.0012 0.0011
Schistosoma mansoni protein kinase 0.0286 0.0253 0.0247
Brugia malayi Protein kinase domain containing protein 0.387 0.6528 0.6528
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0554 0.0722 0.3538
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0149 0.0012 0.0011
Trypanosoma cruzi Protein kinase B 0.0748 0.1061 0.533
Trichomonas vaginalis CMGC family protein kinase 0.0508 0.0642 0.3066
Brugia malayi Protein kinase domain containing protein 0.0176 0.006 0.0059
Loa Loa (eye worm) AGC/PKA protein kinase 0.036 0.0382 0.0381
Schistosoma mansoni tyrosine kinase 0.0149 0.0012 0.0006
Trichomonas vaginalis TKL family protein kinase 0.015 0.0015 0.0072
Schistosoma mansoni adapter molecule crk 0.0234 0.0162 0.0156
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0039 0.0187
Entamoeba histolytica protein kinase, putative 0.1338 0.2094 1
Plasmodium falciparum protein kinase, putative 0.0149 0.0012 0.0118
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.1081 0.1644 0.1644
Entamoeba histolytica protein kinase domain containing protein 0.0554 0.0722 0.3448
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0732 0.1034 0.1033
Schistosoma mansoni protein kinase 0.026 0.0206 0.0201
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0296 0.0269 0.0269
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0305 0.0286 0.0285
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0149 0.0012 0.0011
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0297 0.0272 0.0271
Entamoeba histolytica serine/threonine protein kinase, putative 0.1279 0.1991 0.9507
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Echinococcus multilocularis mitogen activated protein kinase 11 0.0633 0.086 0.086
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0039 0.0187
Brugia malayi Protein kinase domain containing protein 0.0149 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0263 0.0212 0.0211
Echinococcus granulosus dual specificity 0.0169 0.0048 0.0048
Echinococcus granulosus mitogen activated protein kinase 11 0.0633 0.086 0.086
Echinococcus granulosus twitchin 0.0516 0.0655 0.0655
Entamoeba histolytica protein kinase, putative 0.0578 0.0764 0.365
Trichomonas vaginalis CMGC family protein kinase 0.0554 0.0722 0.3448
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0039 0.0187
Brugia malayi Immunoglobulin I-set domain containing protein 0.0215 0.0128 0.0127
Onchocerca volvulus 0.0149 0.0012 0.003
Entamoeba histolytica tyrosine kinase, putative 0.0149 0.0012 0.0057
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.019 0.0084 0.0084
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.1279 0.1991 1
Trichomonas vaginalis CMGC family protein kinase 0.0169 0.0048 0.023
Echinococcus granulosus expressed protein 0.0166 0.0043 0.0042
Schistosoma mansoni protein kinase 0.0409 0.0467 0.0462
Brugia malayi serine/threonine-protein kinase 6 0.0632 0.0858 0.0857
Entamoeba histolytica protein kinase domain containing protein 0.0149 0.0012 0.0057
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0166 0.0042 0.0042
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0328 0.0326 0.0326
Loa Loa (eye worm) hypothetical protein 0.1044 0.158 0.1579
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0182 0.007 0.0069
Schistosoma mansoni tyrosine kinase 0.098 0.1468 0.1462
Plasmodium falciparum cGMP-dependent protein kinase 0.0222 0.0141 0.1403
Echinococcus granulosus tyrosine protein kinase Fyn 0.0625 0.0847 0.0847
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0234 0.0162 0.0161
Onchocerca volvulus 0.0328 0.0326 0.0886
Entamoeba histolytica protein kinase domain containing protein 0.0149 0.0012 0.0057
Trypanosoma cruzi cdc2-related kinase 3 0.0508 0.0642 0.3225
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0149 0.0012 0.0057
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0968 0.1447 0.1447
Loa Loa (eye worm) TK/FER protein kinase 0.0278 0.0238 0.0237
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0039 0.0187
Echinococcus granulosus mitogen activated protein kinase 14 0.0633 0.086 0.086
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0264 0.0214 0.1074
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.036 0.0382 0.1824
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0962 0.1436 0.1436
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.036 0.0382 0.0382
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0701 0.0979 0.0979
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Plasmodium falciparum calcium-dependent protein kinase 4 0.0296 0.0269 0.2674
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0277 0.0237 0.0236
Echinococcus granulosus neuroglian 0.0179 0.0066 0.0065
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0757 0.1078 0.1077
Entamoeba histolytica tyrosine kinase, putative 0.0149 0.0012 0.0057
Leishmania major casein kinase II, putative 0.0455 0.0548 0.2754
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0039 0.0187
Schistosoma mansoni serine/threonine protein kinase 0.1131 0.1733 0.1728
Plasmodium falciparum calcium-dependent protein kinase 5 0.0296 0.0269 0.2674
Trypanosoma brucei casein kinase I, isoform 2 0.0309 0.0293 0.14
Trypanosoma cruzi casein kinase, putative 0.0309 0.0293 0.1472
Loa Loa (eye worm) hypothetical protein 0.033 0.033 0.0329
Brugia malayi SRC-1 0.0625 0.0847 0.0846
Trichomonas vaginalis CAMK family protein kinase 0.0264 0.0214 0.1021
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0238 0.0168 0.0167
Entamoeba histolytica serine/threonine kinase, putative 0.0149 0.0012 0.0057
Entamoeba histolytica protein kinase, putative 0.0312 0.0298 0.1422
Loa Loa (eye worm) TK protein kinase 0.0149 0.0012 0.0011
Echinococcus multilocularis TGF beta receptor type 1 0.019 0.0084 0.0084
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Entamoeba histolytica tyrosine kinase, putative 0.0149 0.0012 0.0057
Echinococcus multilocularis Immunoglobulin 0.0328 0.0326 0.0326
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Schistosoma mansoni tyrosine kinase 0.0149 0.0012 0.0006
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0179 0.0066 0.0065
Trichomonas vaginalis CMGC family protein kinase 0.0455 0.0548 0.2618
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0166 0.0042 0.0036
Schistosoma mansoni vav2 0.0341 0.035 0.0344
Brugia malayi RhoGAP domain containing protein 0.0311 0.0296 0.0295
Entamoeba histolytica SH2-protein kinase domain containing protein 0.024 0.0172 0.0823
Echinococcus multilocularis tyrosine protein kinase ABL1 0.1135 0.174 0.1739
Schistosoma mansoni tyrosine kinase 0.0149 0.0012 0.0006
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0149 0.0012 0.0006
Trichomonas vaginalis AGC family protein kinase 0.036 0.0382 0.1824
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0929 0.1379 0.1378
Schistosoma mansoni protein kinase C 0.0188 0.0082 0.0076
Trichomonas vaginalis CMGC family protein kinase 0.0173 0.0055 0.0265
Entamoeba histolytica protein kinase domain containing protein 0.0149 0.0012 0.0057
Schistosoma mansoni serine/threonine protein kinase 0.0707 0.099 0.0984
Echinococcus multilocularis Glutaredoxin protein 5 0.0606 0.0813 0.0812
Echinococcus multilocularis serine:threonine protein kinase 0.0571 0.0752 0.0751
Brugia malayi Immunoglobulin I-set domain containing protein 0.0152 0.0019 0.0018
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0178 0.0064 0.0063
Schistosoma mansoni tyrosine kinase 0.2485 0.4103 0.41
Brugia malayi Protein kinase domain containing protein 0.0742 0.1051 0.1051
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0632 0.0858 0.4098
Echinococcus granulosus cGMP dependent protein kinase 1 0.0222 0.0141 0.0141
Schistosoma mansoni tyrosine kinase 0.0301 0.0279 0.0273
Trichomonas vaginalis STE family protein kinase 0.0192 0.0089 0.0424
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0508 0.0642 0.0641
Plasmodium falciparum protein kinase 5 0.0508 0.0642 0.6372
Echinococcus multilocularis mitogen activated protein kinase 14 0.0633 0.086 0.086
Brugia malayi Tyrosine-protein kinase abl-1 0.053 0.0679 0.0679
Loa Loa (eye worm) AUR protein kinase 0.0632 0.0858 0.0857
Entamoeba histolytica hypothetical protein 0.0416 0.0481 0.2296
Loa Loa (eye worm) hypothetical protein 0.0152 0.0019 0.0018
Loa Loa (eye worm) TK protein kinase 0.0391 0.0436 0.0436
Plasmodium falciparum tyrosine kinase-like protein 0.0149 0.0012 0.0118
Brugia malayi Immunoglobulin I-set domain containing protein 0.0179 0.0066 0.0065
Schistosoma mansoni protein kinase 0.0149 0.0012 0.0006
Brugia malayi Protein kinase domain containing protein 0.0709 0.0994 0.0993
Schistosoma mansoni serine/threonine protein kinase 0.0578 0.0764 0.0759
Loa Loa (eye worm) hypothetical protein 0.0296 0.0269 0.0268
Loa Loa (eye worm) AUR protein kinase 0.0632 0.0858 0.0857
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0625 0.0847 0.0847
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0149 0.0012 0.0011
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.097 0.145 0.1449
Trichomonas vaginalis AGC family protein kinase 0.1338 0.2094 1
Schistosoma mansoni tyrosine kinase 0.0294 0.0266 0.026
Echinococcus granulosus casein kinase I alpha 0.0309 0.0293 0.0293
Echinococcus granulosus peroxidasin 0.0153 0.0021 0.002
Brugia malayi Temporarily assigned gene name protein 59 0.066 0.0908 0.0907
Echinococcus multilocularis myosin iiia 0.0325 0.0321 0.032
Onchocerca volvulus 0.0617 0.0832 0.2269
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0149 0.0012 0.0057
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0321 0.0314 0.154
Trichomonas vaginalis CAMK family protein kinase 0.0592 0.0789 0.3766
Plasmodium falciparum casein kinase 1 0.0309 0.0293 0.291
Trichomonas vaginalis CAMK family protein kinase 0.0169 0.0048 0.0232
Brugia malayi Cam kinase protein 1 0.0296 0.0269 0.0268
Brugia malayi Protein kinase domain containing protein 0.0149 0.0012 0.0011
Schistosoma mansoni protein kinase C mu 0.0182 0.007 0.0064
Loa Loa (eye worm) TK/FER protein kinase 0.0278 0.0238 0.0237
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Giardia lamblia Kinase, NEK 0.0538 0.0694 0.3445
Echinococcus granulosus roundabout 2 0.0179 0.0066 0.0065
Schistosoma mansoni tyrosine kinase 0.0625 0.0847 0.0842
Brugia malayi Protein kinase domain containing protein 0.0286 0.0253 0.0252
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0309 0.0293 0.1472
Echinococcus granulosus retinal guanylyl cyclase 2 0.0149 0.0012 0.0011
Echinococcus multilocularis calcium:calmodulin dependent protein kinase 0.0169 0.0048 0.0048
Brugia malayi Protein kinase domain containing protein 0.0149 0.0012 0.0011
Echinococcus granulosus neural Wiskott Aldrich syndrome protein 0.0145 0.0006 0.0005
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0346 0.0358 0.0357
Schistosoma mansoni serine/threonine protein kinase 0.0173 0.0055 0.0049
Trichomonas vaginalis CAMK family protein kinase 0.0169 0.0048 0.0232
Echinococcus granulosus tyrosine protein kinase csk 0.0149 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0328 0.0326 0.0325
Schistosoma mansoni serine/threonine protein kinase 0.0264 0.0214 0.0208
Schistosoma mansoni serine/threonine protein kinase 0.0169 0.0048 0.0042
Entamoeba histolytica protein kinase, putative 0.0149 0.0012 0.0057
Schistosoma mansoni hypothetical protein 0.0391 0.0436 0.0431
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0179 0.0066 0.0065
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0164 0.0039 0.0383
Schistosoma mansoni serine/threonine protein kinase 0.0264 0.0214 0.0208
Schistosoma mansoni serine/threonine protein kinase 0.0354 0.0372 0.0367
Loa Loa (eye worm) TK protein kinase 0.0149 0.0012 0.0011
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0201 0.0104 0.0103
Trypanosoma brucei cdc2-related kinase 1 0.0508 0.0642 0.3066
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0542 0.07 0.0699
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.036 0.0382 0.0382
Entamoeba histolytica protein kinase, putative 0.0166 0.0043 0.0204
Entamoeba histolytica tyrosin kinase, putative 0.0162 0.0035 0.0167
Entamoeba histolytica protein kinase, putative 0.0296 0.0269 0.1287
Entamoeba histolytica hypothetical protein 0.0149 0.0012 0.0057
Trichomonas vaginalis CMGC family protein kinase 0.0321 0.0314 0.15
Echinococcus granulosus tyrosine protein kinase Lyn 0.0737 0.1042 0.1041
Onchocerca volvulus 0.0149 0.0012 0.003
Brugia malayi probable protein kinase 0.0409 0.0467 0.0466
Trichomonas vaginalis CMGC family protein kinase 0.0243 0.0178 0.085
Echinococcus granulosus tyrosine protein kinase Fyn 0.0625 0.0847 0.0847
Echinococcus multilocularis casein kinase I gamma 0.0243 0.0177 0.0176
Giardia lamblia Kinase, NEK 0.0538 0.0694 0.3445
Schistosoma mansoni protein kinase 0.0256 0.0201 0.0195
Echinococcus granulosus casein kinase I alpha 0.0309 0.0293 0.0293
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0455 0.0548 0.5442
Brugia malayi diacylglycerol kinase 0.0182 0.007 0.0069
Schistosoma mansoni septate junction protein 0.0152 0.0019 0.0013
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0243 0.0178 0.0872
Echinococcus granulosus tyrosine kinase 0.0278 0.0238 0.0237
Echinococcus multilocularis mitogen activated protein kinase 11 0.0633 0.086 0.086
Brugia malayi Protein kinase domain containing protein 0.0278 0.0238 0.0237
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0321 0.0314 0.1578
Schistosoma mansoni septate junction protein 0.0152 0.0019 0.0013
Onchocerca volvulus 0.0278 0.0238 0.0646
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Trichomonas vaginalis CMGC family protein kinase 0.0455 0.0548 0.2618
Schistosoma mansoni serine/threonine protein kinase 0.0508 0.0642 0.0636
Plasmodium falciparum protein kinase, putative 0.0149 0.0012 0.0118
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0296 0.0269 0.0269
Brugia malayi Hr1 repeat family protein 0.0843 0.1228 0.1227
Onchocerca volvulus 0.0173 0.0055 0.0148
Brugia malayi Tyrosine-protein kinase PR2 0.0149 0.0012 0.0011
Trichomonas vaginalis CAMK family protein kinase 0.0264 0.0214 0.1021
Echinococcus granulosus serine:threonine protein kinase 3 0.1037 0.1568 0.1567
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0192 0.0089 0.0446
Loa Loa (eye worm) hypothetical protein 0.0149 0.0012 0.0011
Trichomonas vaginalis AGC family protein kinase 0.0754 0.1072 0.512
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0782 0.1121 0.1121
Schistosoma mansoni nck2/grb4 0.0234 0.0162 0.0156
Schistosoma mansoni diacylglycerol kinase theta 0.0182 0.007 0.0064
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0321 0.0314 0.1578
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.036 0.0382 0.1824
Trichomonas vaginalis STE family protein kinase 0.0346 0.0358 0.1708
Echinococcus granulosus casein kinase I gamma 0.0243 0.0177 0.0176
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.036 0.0382 0.1824
Echinococcus granulosus rho-associated protein kinase 1 0.1319 0.2062 0.2062
Entamoeba histolytica receptor protein kinase, putative 0.0149 0.0012 0.0057
Trypanosoma brucei rac serine-threonine kinase, putative 0.1338 0.2094 1
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0149 0.0012 0.0011
Schistosoma mansoni titin 0.0215 0.0128 0.0122
Schistosoma mansoni serine/threonine protein kinase 0.0321 0.0314 0.0308
Schistosoma mansoni serine/threonine kinase 0.0701 0.0979 0.0974
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0616 0.0831 0.0831
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.052 0.0663 0.0662
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.036 0.0382 0.0382
Trichomonas vaginalis conserved hypothetical protein 0.015 0.0014 0.0067
Brugia malayi P38 map kinase family protein 2 0.0633 0.086 0.0859
Echinococcus granulosus tyrosine protein kinase Src42A 0.0625 0.0847 0.0847
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0633 0.086 0.0859
Brugia malayi Protein kinase domain containing protein 0.0149 0.0012 0.0011
Brugia malayi Protein kinase domain containing protein 0.0149 0.0012 0.0011
Trichomonas vaginalis AGC family protein kinase 0.0632 0.0858 0.4098
Schistosoma mansoni tyrosine kinase 0.0149 0.0012 0.0006
Trichomonas vaginalis CAMK family protein kinase 0.0264 0.0214 0.1021
Trichomonas vaginalis AGC family protein kinase 0.0632 0.0858 0.4098
Echinococcus multilocularis growth factor receptor bound protein 2 0.0234 0.0162 0.0162
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0732 0.1034 0.1033
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0296 0.0269 0.2674
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.036 0.0382 0.3792
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0278 0.0238 0.0237
Schistosoma mansoni serine/threonine protein kinase 0.0264 0.0214 0.0208
Brugia malayi protein kinase C II. 0.0889 0.1309 0.1308
Schistosoma mansoni protein kinase 0.019 0.0084 0.0078
Echinococcus granulosus RNA directed DNA polymerase 0.0203 0.0107 0.0107
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.036 0.0382 0.3792
Trichomonas vaginalis AGC family protein kinase 0.0538 0.0694 0.3313
Schistosoma mansoni rap gtpase-activating protein 0.0166 0.0042 0.0036
Trichomonas vaginalis CAMK family protein kinase 0.0169 0.0048 0.0232
Brugia malayi Protein kinase domain containing protein 0.0149 0.0012 0.0011
Brugia malayi hypothetical protein 0.0278 0.0238 0.0237
Trichomonas vaginalis CAMK family protein kinase 0.0264 0.0214 0.1021
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0698 0.0973 0.0972
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0234 0.0162 0.0161
Echinococcus granulosus mitogen activated protein kinase 0.0321 0.0314 0.0314
Echinococcus multilocularis tyrosine protein kinase HCK 0.0391 0.0436 0.0436
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0201 0.0104 0.0494
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.029 0.026 0.0259
Brugia malayi C1-like domain containing protein 0.0698 0.0973 0.0972
Trichomonas vaginalis STE family protein kinase 0.0325 0.0321 0.1532
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0625 0.0847 0.0847
Loa Loa (eye worm) hypothetical protein 0.0182 0.007 0.0069
Echinococcus granulosus contactin 0.0179 0.0066 0.0065
Plasmodium falciparum calcium-dependent protein kinase 2 0.0296 0.0269 0.2674
Giardia lamblia Kinase, STE STE20 0.0192 0.0089 0.0388
Onchocerca volvulus 0.0278 0.0238 0.0646
Entamoeba histolytica protein kinase domain containing protein 0.0149 0.0012 0.0057
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.4711 0.8001 0.8001
Schistosoma mansoni serine/threonine protein kinase 0.0166 0.0043 0.0037
Brugia malayi Protein kinase domain containing protein 0.0143 0.0002 0.0001
Entamoeba histolytica protein kinase domain containing protein 0.0149 0.0012 0.0057
Entamoeba histolytica protein kinase, putative 0.0149 0.0012 0.0057
Entamoeba histolytica tyrosine kinase, putative 0.0149 0.0012 0.0057
Schistosoma mansoni serine/threonine protein kinase 0.0243 0.0178 0.0172
Echinococcus multilocularis tyrosine protein kinase otk 0.0152 0.0019 0.0018
Loa Loa (eye worm) gastrulation defective protein 1 0.0144 0.0003 0.0002
Schistosoma mansoni tyrosine kinase 0.0149 0.0012 0.0006
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.026 0.0206 0.1037
Brugia malayi Temporarily assigned gene name protein 59 0.0166 0.0042 0.0041
Onchocerca volvulus 0.0149 0.0012 0.003
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0325 0.0321 0.1532
Echinococcus multilocularis roundabout 2 0.0507 0.064 0.064
Brugia malayi Protein kinase domain containing protein 0.0243 0.0178 0.0177
Plasmodium vivax casein kinase 1, putative 0.0309 0.0293 0.291
Schistosoma mansoni serine/threonine protein kinase 0.0962 0.1436 0.1431
Trichomonas vaginalis STE family protein kinase 0.0192 0.0089 0.0424
Brugia malayi Variant SH3 domain containing protein 0.0311 0.0296 0.0295
Echinococcus multilocularis calcium activated potassium channel 0.0502 0.0631 0.0631
Schistosoma mansoni protein kinase 0.0149 0.0012 0.0006
Trypanosoma cruzi casein kinase, putative 0.0309 0.0293 0.1472
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0632 0.0858 0.0858
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0192 0.0089 0.0088
Echinococcus multilocularis cyclin dependent kinase 5 0.0508 0.0642 0.0641
Echinococcus multilocularis casein kinase I alpha 0.0309 0.0293 0.0293
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0149 0.0014 0.0065
Trichomonas vaginalis STE family protein kinase 0.0346 0.0358 0.1708
Echinococcus multilocularis serine:threonine protein kinase 3 0.1037 0.1568 0.1567
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0149 0.0012 0.0057
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Echinococcus multilocularis N chimaerin 0.0311 0.0296 0.0296
Echinococcus multilocularis insulin receptor 0.1813 0.2926 0.2926
Loa Loa (eye worm) hypothetical protein 0.0355 0.0373 0.0372
Leishmania major casein kinase, putative 0.0309 0.0293 0.1472
Toxoplasma gondii histone kinase SNF1, putative 0.0264 0.0214 0.1048
Plasmodium vivax serine/threonine protein kinase, putative 0.0166 0.0043 0.0423
Brugia malayi Sex muscle abnormal protein 5 0.0234 0.0162 0.0161
Entamoeba histolytica protein kinase, putative 0.0149 0.0012 0.0057
Loa Loa (eye worm) hypothetical protein 0.0862 0.1262 0.1261
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0264 0.0214 0.0213
Echinococcus granulosus retinal guanylyl cyclase 2 0.0149 0.0012 0.0011
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0554 0.0722 0.3626
Trichomonas vaginalis CMGC family protein kinase 0.0455 0.0548 0.2618
Giardia lamblia Kinase, CK1 Casein kinase 0.0309 0.0293 0.1421
Echinococcus granulosus protein kinase c epsilon type 0.0889 0.1309 0.1309
Echinococcus multilocularis PAK box P21 Rho binding 0.0256 0.0201 0.02
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0572 0.0754 0.3786
Brugia malayi Protein kinase domain containing protein 0.0149 0.0012 0.0011
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0311 0.0296 0.029
Echinococcus granulosus receptor type guanylyl cyclase 0.0149 0.0012 0.0011
Plasmodium vivax protein kinase, putative 0.0185 0.0076 0.0757
Echinococcus multilocularis protein KINase family member (kin 25) 0.0219 0.0134 0.0134
Loa Loa (eye worm) TK/EGFR protein kinase 0.2485 0.4103 0.4103
Entamoeba histolytica tyrosin kinase, putative 0.0149 0.0012 0.0057
Entamoeba histolytica tyrosine kinase, putative 0.0149 0.0012 0.0057
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0176 0.006 0.0059
Echinococcus granulosus cyclin dependent kinase 0.0508 0.0642 0.0641
Echinococcus multilocularis roundabout 2 0.0179 0.0066 0.0065
Echinococcus multilocularis Diacylglycerol kinase theta 0.0182 0.007 0.007
Schistosoma mansoni tyrosine kinase 0.1476 0.2336 0.2331
Trichomonas vaginalis CMGC family protein kinase 0.0173 0.0055 0.0265
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0296 0.0269 0.0268
Schistosoma mansoni serine/threonine protein kinase 0.0757 0.1078 0.1072
Trichomonas vaginalis CAMK family protein kinase 0.0589 0.0784 0.3743
Trypanosoma cruzi aurora B kinase, putative 0.0632 0.0858 0.4311
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0227 0.015 0.0149
Brugia malayi casein kinase 1, delta 0.0309 0.0293 0.0292
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0149 0.0012 0.0011
Entamoeba histolytica PH domain containing protein kinase, putative 0.039 0.0436 0.208
Plasmodium vivax calcium-dependent protein kinase, putative 0.0296 0.0269 0.2674
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0152 0.0019 0.0018
Echinococcus multilocularis cyclin dependent kinase 19 0.0255 0.0198 0.0197
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0255 0.0198 0.0197
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Schistosoma mansoni vesicular amine transporter 0.0328 0.0326 0.0321
Echinococcus multilocularis raf serine:threonine protein kinase 0.033 0.033 0.033
Trichomonas vaginalis CAMK family protein kinase 0.0264 0.0214 0.1021
Echinococcus granulosus protein kinase shaggy 0.0554 0.0722 0.0721
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0297 0.0272 0.0271
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0104 0.0497
Echinococcus granulosus calcium dependent protein kinase 0.0184 0.0075 0.0074
Giardia lamblia Kinase, PLK 0.1279 0.1991 1
Entamoeba histolytica PH domain containing protein kinase, putative 0.0748 0.1061 0.5067
Schistosoma mansoni rac gtpase activating protein 0.0182 0.007 0.0064
Entamoeba histolytica serine/threonine kinase, putative 0.0149 0.0012 0.0057
Entamoeba histolytica protein kinase, putative 0.0149 0.0012 0.0057
Entamoeba histolytica hypothetical protein 0.0149 0.0012 0.0057
Echinococcus multilocularis protein kinase shaggy 0.0554 0.0722 0.0721
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0152 0.0019 0.0018
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0255 0.0198 0.0197
Toxoplasma gondii aurora kinase 0.0632 0.0858 0.4206
Echinococcus multilocularis aurora kinase A 0.0632 0.0858 0.0858
Brugia malayi MAP kinase sur-1 0.0321 0.0314 0.0313
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0305 0.0286 0.0285
Schistosoma mansoni serine/threonine protein kinase 0.1783 0.2873 0.2869
Loa Loa (eye worm) hypothetical protein 0.0153 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.0152 0.0019 0.0018
Trypanosoma cruzi cdc2-related kinase 1 0.0508 0.0642 0.3225
Brugia malayi Protein kinase domain containing protein 0.0149 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0355 0.0373 0.0372
Schistosoma mansoni cell adhesion molecule 0.0431 0.0506 0.05
Trichomonas vaginalis STE family protein kinase 0.0192 0.0089 0.0424
Loa Loa (eye worm) AUR protein kinase 0.0632 0.0858 0.0857
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0149 0.0012 0.0011
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0296 0.0269 0.1287
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0149 0.0012 0.0057
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0554 0.0722 0.3626
Trichomonas vaginalis CAMK family protein kinase 0.1279 0.1991 0.9507
Echinococcus multilocularis heat shock protein 70 0.0149 0.0012 0.0011
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0486 0.0603 0.0603
Onchocerca volvulus 0.0198 0.0099 0.0266
Loa Loa (eye worm) hypothetical protein 0.0149 0.0012 0.0011
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.036 0.0382 0.1919
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0166 0.0043 0.0214
Trichomonas vaginalis conserved hypothetical protein 0.0235 0.0163 0.0778
Brugia malayi Protein kinase domain containing protein 0.0508 0.0642 0.0641
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0149 0.0012 0.0011
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0508 0.0642 0.3225
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0297 0.0272 0.0271
Schistosoma mansoni hypothetical protein 0.0166 0.0042 0.0036
Leishmania major protein kinase, putative 0.0243 0.0178 0.0894
Trypanosoma cruzi cdc2-related kinase 1 0.0508 0.0642 0.3225
Echinococcus multilocularis casein kinase ii subunit alpha 0.0455 0.0548 0.0548
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0149 0.0012 0.0057
Echinococcus granulosus nervana 2 0.0606 0.0813 0.0812
Schistosoma mansoni serine/threonine protein kinase 0.0309 0.0293 0.0287
Echinococcus granulosus tyrosine kinase 0.052 0.0662 0.0662
Entamoeba histolytica hypothetical protein 0.0149 0.0012 0.0057
Entamoeba histolytica p21-activated kinase 0.0377 0.0411 0.1964
Echinococcus granulosus tyrosine protein kinase HCK 0.0391 0.0436 0.0436
Brugia malayi Immunoglobulin I-set domain containing protein 0.0152 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.0278 0.0238 0.0237
Entamoeba histolytica hypothetical protein 0.0145 0.0006 0.0028
Entamoeba histolytica protein kinase, putative 0.0578 0.0764 0.365
Trichomonas vaginalis CAMK family protein kinase 0.1279 0.1991 0.9507
Brugia malayi Protein kinase domain containing protein 0.0149 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0298 0.0273 0.0272
Brugia malayi Egg laying defective protein 4 0.0222 0.0141 0.014
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0149 0.0012 0.0011
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Echinococcus multilocularis rho associated protein kinase 0.1319 0.2062 0.2062
Loa Loa (eye worm) RGC/RGC protein kinase 0.0149 0.0012 0.0011
Brugia malayi Protein kinase domain containing protein 0.0592 0.0789 0.0788
Brugia malayi Protein kinase domain containing protein 0.097 0.145 0.1449
Schistosoma mansoni serine/threonine protein kinase 0.0502 0.0631 0.0625
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0321 0.0314 0.1578
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0633 0.086 0.432
Echinococcus granulosus tyrosine protein kinase pr2 0.0149 0.0012 0.0011
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0149 0.0012 0.0011
Entamoeba histolytica tyrosine kinase, putative 0.0149 0.0012 0.0057
Brugia malayi Protein kinase domain containing protein 0.0701 0.0979 0.0978
Entamoeba histolytica protein kinase domain containing protein 0.0149 0.0012 0.0057
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0625 0.0847 0.0847
Onchocerca volvulus 0.1124 0.1721 0.4695
Echinococcus multilocularis serine:threonine protein kinase N2 0.0843 0.1228 0.1228
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0255 0.0198 0.0197
Entamoeba histolytica tyrosine kinase, putative 0.0149 0.0012 0.0057
Schistosoma mansoni serine/threonine protein kinase 0.1092 0.1664 0.1659
Trichomonas vaginalis AGC family protein kinase 0.1338 0.2094 1
Echinococcus multilocularis serine:threonine protein kinase 0.0571 0.0752 0.0751
Trichomonas vaginalis AGC family protein kinase 0.0723 0.1019 0.4864
Echinococcus granulosus activated cdc42 kinase 1 0.033 0.033 0.033
Brugia malayi hypothetical protein 0.0166 0.0042 0.0041
Schistosoma mansoni tyrosine kinase 0.0625 0.0847 0.0842
Echinococcus granulosus protein kinase c eta type 0.0182 0.007 0.007
Schistosoma mansoni tyrosine kinase 0.0149 0.0012 0.0006
Entamoeba histolytica protein kinase domain containing protein 0.0162 0.0035 0.0167
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0166 0.0043 0.0042
Loa Loa (eye worm) CDC7 protein kinase 0.0173 0.0055 0.0054
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0321 0.0314 0.15
Toxoplasma gondii AGC kinase 0.036 0.0382 0.1872
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0757 0.1078 0.1077
Echinococcus multilocularis tyrosine protein kinase Abl 0.0711 0.0997 0.0996
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Loa Loa (eye worm) AGC/AKT protein kinase 0.1338 0.2094 0.2093
Entamoeba histolytica diacylglycerol kinase, putative 0.0182 0.007 0.0336
Schistosoma mansoni serine/threonine protein kinase 0.0632 0.0858 0.0853
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0625 0.0847 0.0847
Loa Loa (eye worm) TK protein kinase 0.0149 0.0012 0.0011
Echinococcus multilocularis Rac GTPase activating protein 1 0.0182 0.007 0.007
Brugia malayi map kinase activated protein kinase protein 2 0.1783 0.2873 0.2872
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0632 0.0858 0.0858
Loa Loa (eye worm) hypothetical protein 0.0355 0.0373 0.0372
Loa Loa (eye worm) TK/ALK protein kinase 0.0711 0.0998 0.0997
Brugia malayi ephrin receptor 1 precursor 0.0303 0.0282 0.0281
Schistosoma mansoni protein kinase 0.0782 0.1121 0.1116
Entamoeba histolytica protein kinase domain containing protein 0.0149 0.0012 0.0057
Brugia malayi Protein kinase domain containing protein 0.0255 0.0198 0.0197
Loa Loa (eye worm) hypothetical protein 0.0467 0.057 0.0569
Schistosoma mansoni serine/threonine protein kinase 0.0296 0.0269 0.0264
Loa Loa (eye worm) protein kinase domain-containing protein 0.0243 0.0177 0.0176
Plasmodium falciparum serine/threonine protein kinase KIN 0.0264 0.0214 0.2122
Echinococcus multilocularis protein kinase c iota type 0.1307 0.2041 0.204
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Brugia malayi Protein kinase domain 0.0346 0.0358 0.0357
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0903 0.1332 0.1332
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.036 0.0382 0.1919
Entamoeba histolytica protein kinase, putative 0.0554 0.0722 0.3448
Schistosoma mansoni protein kinase 0.0346 0.0358 0.0352
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0633 0.086 0.432
Toxoplasma gondii casein kinase I 0.0309 0.0293 0.1437
Loa Loa (eye worm) AGC/NDR protein kinase 0.0701 0.0979 0.0978
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0152 0.0019 0.0013
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0222 0.0141 0.0141
Schistosoma mansoni ephrin receptor 0.0476 0.0586 0.058
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0701 0.0979 0.0979
Loa Loa (eye worm) hypothetical protein 0.0481 0.0593 0.0592
Loa Loa (eye worm) hypothetical protein 0.0188 0.0082 0.0081
Echinococcus multilocularis Immunoglobulin 0.0328 0.0326 0.0326
Echinococcus granulosus epidermal growth factor receptor 0.1624 0.2596 0.2596
Schistosoma mansoni tyrosine kinase 0.1624 0.2596 0.2591
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0149 0.0012 0.0006
Schistosoma mansoni serine/threonine protein kinase 0.0188 0.0081 0.0075
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0929 0.1379 0.1378
Echinococcus granulosus tyrosine protein kinase Src64B 0.0625 0.0847 0.0847
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0312 0.0298 0.0297
Schistosoma mansoni growth factor receptor-bound protein 0.0239 0.0171 0.0165
Schistosoma mansoni tyrosine kinase 0.1624 0.2596 0.2591
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0243 0.0178 0.085
Loa Loa (eye worm) hypothetical protein 0.0234 0.0162 0.0161
Brugia malayi hypothetical protein 0.0318 0.0309 0.0308
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.097 0.145 0.1449
Echinococcus granulosus serine:threonine protein kinase PLK1 0.1279 0.1991 0.199
Trichomonas vaginalis CAMK family protein kinase 0.1279 0.1991 0.9507
Echinococcus granulosus TGF beta receptor type 1 0.019 0.0084 0.0084
Echinococcus multilocularis receptor type guanylyl cyclase 0.0149 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0476 0.0586 0.0585
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0149 0.0012 0.0011
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0149 0.0012 0.0057
Echinococcus multilocularis neural Wiskott Aldrich syndrome protein 0.0145 0.0006 0.0005
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0296 0.0269 0.0268
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Loa Loa (eye worm) hypothetical protein 0.0149 0.0012 0.0011
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0346 0.0358 0.0357
Loa Loa (eye worm) hypothetical protein 0.0203 0.0107 0.0106
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0318 0.0309 0.0308
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0166 0.0042 0.0213
Schistosoma mansoni unc-13 (munc13) 0.0188 0.0082 0.0076
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.184 0.2973 0.2973
Schistosoma mansoni cell adhesion molecule 0.0179 0.0066 0.006
Plasmodium vivax unspecified product 0.0455 0.0548 0.5442
Schistosoma mansoni serine/threonine-protein kinase 0.0748 0.1061 0.1056
Brugia malayi Protein kinase domain containing protein 0.0149 0.0012 0.0011
Echinococcus granulosus cGMP dependent protein kinase 1 0.0222 0.0141 0.0141
Echinococcus multilocularis RNA directed DNA polymerase 0.0203 0.0107 0.0107
Entamoeba histolytica casein kinase, putative 0.0309 0.0293 0.14
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Echinococcus multilocularis integrin linked protein kinase 0.0149 0.0012 0.0011
Trichomonas vaginalis AGC family protein kinase 0.1338 0.2094 1
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.052 0.0662 0.0662
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0325 0.0321 0.1612
Echinococcus multilocularis tyrosine protein kinase Srms 0.052 0.0662 0.0662
Brugia malayi SH2 domain containing protein 0.0278 0.0238 0.0237
Brugia malayi P21-Rho-binding domain containing protein 0.0145 0.0006 0.0005
Entamoeba histolytica protein kinase domain containing protein 0.0149 0.0012 0.0057
Echinococcus granulosus 3'partial|serine:threonine protein kinase PAK 2 0.0145 0.0006 0.0005
Trypanosoma brucei protein kinase, putative 0.0321 0.0314 0.15
Echinococcus multilocularis expressed protein 0.0166 0.0043 0.0042
Loa Loa (eye worm) serine/threonine protein kinase 0.0149 0.0012 0.0011
Trypanosoma brucei Casein kinase II 0.0455 0.0548 0.2618
Leishmania major protein kinase, putative 0.0149 0.0012 0.006
Giardia lamblia Kinase, CMGC CDK 0.0508 0.0642 0.3184
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0249 0.0187 0.0187
Entamoeba histolytica protein kinase domain containing protein 0.0149 0.0012 0.0057
Schistosoma mansoni serine/threonine kinase 0.0592 0.0789 0.0783
Echinococcus granulosus insulin receptor 0.1813 0.2926 0.2926
Schistosoma mansoni protein kinase 0.0149 0.0012 0.0006
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0166 0.0042 0.0213
Entamoeba histolytica PH domain containing protein kinase, putative 0.039 0.0436 0.208
Loa Loa (eye worm) TK/FER protein kinase 0.0278 0.0238 0.0237
Giardia lamblia Kinase, AGC AKT 0.0542 0.07 0.3479
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0278 0.0238 0.1135
Plasmodium falciparum calcium-dependent protein kinase 3 0.0296 0.0269 0.2674
Entamoeba histolytica protein kinase, putative 0.0166 0.0043 0.0204
Loa Loa (eye worm) hypothetical protein 0.036 0.0382 0.0381
Loa Loa (eye worm) TK/FER protein kinase 0.0278 0.0238 0.0237
Trypanosoma cruzi casein kinase, putative 0.0309 0.0293 0.1472
Echinococcus granulosus CDC7 cell division cycle 7 0.0173 0.0055 0.0055
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0633 0.086 0.432
Brugia malayi Protein kinase domain containing protein 0.0149 0.0012 0.0011
Loa Loa (eye worm) CAMK protein kinase 0.0215 0.0128 0.0127
Trichomonas vaginalis CAMK family protein kinase 0.0571 0.0752 0.3589
Schistosoma mansoni serine/threonine protein kinase 0.0255 0.0198 0.0192
Loa Loa (eye worm) hypothetical protein 0.0328 0.0326 0.0325
Echinococcus multilocularis activin receptor type 0.0661 0.091 0.0909
Entamoeba histolytica cell division protein kinase 2, putative 0.0508 0.0642 0.3066
Entamoeba histolytica tyrosin kinase, putative 0.0149 0.0012 0.0057
Loa Loa (eye worm) hypothetical protein 0.0179 0.0066 0.0065
Brugia malayi Protein kinase domain containing protein 0.0278 0.0238 0.0237
Entamoeba histolytica tyrosin kinase, putative 0.0149 0.0012 0.0057
Entamoeba histolytica protein kinase, putative 0.0149 0.0012 0.0057
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0149 0.0012 0.0011
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0178 0.0064 0.0063
Onchocerca volvulus 0.0149 0.0012 0.003
Schistosoma mansoni tyrosine kinase 0.0149 0.0012 0.0006
Echinococcus multilocularis dual specificity 0.0169 0.0048 0.0048
Schistosoma mansoni protein kinase 0.0903 0.1332 0.1327
Brugia malayi Guanylyl cyclase protein 23 0.0149 0.0012 0.0011
Brugia malayi SH2 domain containing protein 0.0278 0.0238 0.0237
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0149 0.0012 0.0011
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0149 0.0012 0.0006
Brugia malayi p70 ribosomal S6 kinase beta 0.1307 0.204 0.2039
Echinococcus multilocularis tyrosine protein kinase Blk 0.052 0.0662 0.0662
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0311 0.0296 0.029
Echinococcus multilocularis serine:threonine protein kinase N2 0.0701 0.0979 0.0979
Loa Loa (eye worm) TK/FER protein kinase 0.0149 0.0012 0.0011
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0757 0.1078 0.1077
Brugia malayi Protein kinase domain containing protein 0.0723 0.1019 0.1018
Echinococcus granulosus ephrin type A receptor 4 A 0.0476 0.0586 0.0585
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0219 0.0134 0.0134
Entamoeba histolytica protein kinase 2, putative 0.0717 0.1007 0.4811
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.026 0.0206 0.1037
Giardia lamblia Kinase, CMGC GSK 0.0554 0.0722 0.3588
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0149 0.0012 0.0057
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0169 0.0048 0.0242
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0296 0.0269 0.0269
Onchocerca volvulus 0.0309 0.0293 0.0798
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0169 0.0048 0.0047
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0179 0.0066 0.0065
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0222 0.0141 0.0693
Entamoeba histolytica protein kinase domain containing protein 0.0149 0.0012 0.0057
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0164 0.0039 0.0187
Echinococcus granulosus tyrosine protein kinase csk 0.0149 0.0012 0.0011
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.036 0.0382 0.1919
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0566 0.0743 0.0742
Echinococcus granulosus dual specificity protein kinase clk2 0.0243 0.0178 0.0177
Schistosoma mansoni tyrosine kinase 0.0383 0.0422 0.0417
Schistosoma mansoni atypical protein kinase C 0.1338 0.2095 0.209
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0203 0.0107 0.0107
Onchocerca volvulus 0.0166 0.0042 0.0113
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0264 0.0214 0.1074
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0179 0.0066 0.0065
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0149 0.0012 0.0011
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0238 0.0168 0.0168
Entamoeba histolytica protein kinase, putative 0.0302 0.0281 0.1341
Brugia malayi Protein kinase domain containing protein 0.0149 0.0012 0.0011
Echinococcus multilocularis tyrosine protein kinase 0.0411 0.0472 0.0471
Brugia malayi Pleckstrin Homology Domain 0.0212 0.0124 0.0123
Loa Loa (eye worm) hypothetical protein 0.0182 0.007 0.0069
Loa Loa (eye worm) TK/FER protein kinase 0.0278 0.0238 0.0237
Onchocerca volvulus 0.0149 0.0012 0.003
Plasmodium vivax tyrosine kinase-like protein, putative 0.0164 0.0039 0.0383
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Leishmania major protein kinase A catalytic subunit 0.036 0.0382 0.1919
Loa Loa (eye worm) hypothetical protein 0.0328 0.0326 0.0325
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0321 0.0314 0.0313
Echinococcus multilocularis rac serine:threonine kinase 0.0748 0.1061 0.1061
Echinococcus multilocularis transfer RNA-Thr 0.033 0.033 0.033
Entamoeba histolytica protein kinase domain containing protein 0.0297 0.0272 0.1298
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0757 0.1078 0.1077
Echinococcus granulosus tyrosine kinase 0.0149 0.0012 0.0011
Leishmania major protein kinase, putative 0.026 0.0206 0.1037
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0198 0.0099 0.0495
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0179 0.0066 0.006
Brugia malayi Protein kinase domain containing protein 0.0149 0.0012 0.0011
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Toxoplasma gondii STE kinase 0.0149 0.0012 0.0058
Schistosoma mansoni protein kinase 0.0192 0.0089 0.0083
Schistosoma mansoni ste20-related kinase 0.0823 0.1193 0.1188
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0166 0.0043 0.0204
Loa Loa (eye worm) TK/RYK protein kinase 0.0149 0.0012 0.0011
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0929 0.1379 0.1378
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0929 0.1379 0.3761
Echinococcus granulosus hemicentin 1 0.0152 0.0019 0.0018
Schistosoma mansoni serine/threonine RGC 0.0149 0.0012 0.0006
Entamoeba histolytica protein kinase, putative 0.1307 0.204 0.9744
Schistosoma mansoni protein kinase 0.0782 0.1121 0.1116
Loa Loa (eye worm) hypothetical protein 0.0153 0.0019 0.0018
Entamoeba histolytica tyrosine kinase, putative 0.0149 0.0012 0.0057
Onchocerca volvulus 0.0161 0.0033 0.0087
Schistosoma mansoni protein kinase 0.0149 0.0012 0.0006
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0321 0.0314 0.1578
Giardia lamblia Kinase, CAMK CAMKL 0.0264 0.0214 0.102
Brugia malayi bone morphogenetic protein type 1 receptor 0.0227 0.015 0.0149
Loa Loa (eye worm) TK/FER protein kinase 0.0149 0.0012 0.0011
Onchocerca volvulus 0.0278 0.0238 0.0646
Entamoeba histolytica protein kinase, putative 0.0149 0.0012 0.0057
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0166 0.0043 0.0042
Loa Loa (eye worm) hypothetical protein 0.0153 0.0021 0.002
Toxoplasma gondii AGC kinase 0.036 0.0382 0.1872
Schistosoma mansoni hypothetical protein 0.0149 0.0012 0.0006
Trypanosoma brucei protein kinase, putative 0.0554 0.0722 0.3448
Echinococcus granulosus cGMP dependent protein kinase 0.0222 0.0141 0.0141
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0243 0.0177 0.0176
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0296 0.0269 0.132
Onchocerca volvulus 0.0862 0.1262 0.3442
Echinococcus multilocularis epidermal growth factor receptor 0.1624 0.2596 0.2596
Echinococcus multilocularis cyclin dependent kinase 1 0.0508 0.0642 0.0641
Echinococcus granulosus Diacylglycerol kinase theta 0.0182 0.007 0.007
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Brugia malayi Immunoglobulin I-set domain containing protein 0.1045 0.1582 0.1581
Entamoeba histolytica protein kinase, putative 0.0149 0.0012 0.0057
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0149 0.0012 0.0058
Entamoeba histolytica protein kinase, putative 0.0149 0.0012 0.0057
Plasmodium vivax tyrosine kinase-like protein, putative 0.0149 0.0012 0.0118
Echinococcus multilocularis serine:threonine protein kinase 38 0.0701 0.0979 0.0979
Schistosoma mansoni serine/threonine protein kinase 0.0508 0.0642 0.0636
Giardia lamblia Kinase, AGC PKA 0.0717 0.1007 0.5031
Brugia malayi serine/threonine protein kinase 6 0.0632 0.0858 0.0857
Trichomonas vaginalis STE family protein kinase 0.0538 0.0694 0.3313
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.036 0.0382 0.0382
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0404 0.0459 0.0458
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0554 0.0722 0.0716
Trichomonas vaginalis STE family protein kinase 0.0256 0.0201 0.0958
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0328 0.0326 0.0321
Schistosoma mansoni ephrin receptor 0.0175 0.0059 0.0053
Brugia malayi Variant SH3 domain containing protein 0.0234 0.0162 0.0161
Loa Loa (eye worm) TK/INSR protein kinase 0.1813 0.2926 0.2925
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0723 0.1019 0.1018
Schistosoma mansoni tyrosine kinase 0.1006 0.1514 0.1509
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0929 0.1379 0.1378
Loa Loa (eye worm) TK protein kinase 0.0149 0.0012 0.0011
Echinococcus granulosus epidermal growth factor receptor 0.2485 0.4103 0.4103
Echinococcus granulosus cyclin dependent kinase 1 0.0508 0.0642 0.0641
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.1783 0.2873 0.2873
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0264 0.0214 0.1021
Schistosoma mansoni serine/threonine protein kinase 0.1279 0.1991 0.1986
Echinococcus multilocularis mitogen activated protein kinase 3 0.0321 0.0314 0.0314
Trypanosoma cruzi p21-activated kinase 3, putative 0.0201 0.0104 0.052
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0149 0.0012 0.0011
Schistosoma mansoni tyrosine kinase 0.0219 0.0134 0.0129
Loa Loa (eye worm) hypothetical protein 0.0182 0.007 0.0069
Schistosoma mansoni tyrosine kinase 0.0149 0.0012 0.0006
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0606 0.0813 0.0812
Brugia malayi Protein kinase domain containing protein 0.0149 0.0012 0.0011
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0201 0.0104 0.0103
Trichomonas vaginalis CMGC family protein kinase 0.0554 0.0722 0.3448
Entamoeba histolytica protein kinase domain containing protein 0.0632 0.0858 0.4098
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0538 0.0694 0.6885
Loa Loa (eye worm) AGC/PKN protein kinase 0.0843 0.1228 0.1227
Loa Loa (eye worm) hypothetical protein 0.0149 0.0012 0.0011
Trypanosoma brucei Flagellum attachment zone protein 20 0.0149 0.0012 0.0057
Echinococcus multilocularis hypothetical protein 0.0391 0.0436 0.0436
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0346 0.0358 0.0357
Schistosoma mansoni serine/threonine protein kinase 0.097 0.145 0.1445
Schistosoma mansoni serine/threonine protein kinase 0.0312 0.0298 0.0292
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0578 0.0764 0.3839
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0149 0.0012 0.0057
Loa Loa (eye worm) TK/FER protein kinase 0.0149 0.0012 0.0011
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Brugia malayi hypothetical protein 0.0149 0.0012 0.0011
Trypanosoma brucei Pseudokinase, putative 0.0149 0.0012 0.0057
Echinococcus multilocularis kinase suppressor of Ras 1 0.0149 0.0012 0.0011
Echinococcus granulosus protein tyrosine kinase 0.0703 0.0982 0.0982
Trypanosoma cruzi casein kinase, putative 0.0309 0.0293 0.1472
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Onchocerca volvulus 0.0188 0.0082 0.022
Echinococcus granulosus Protein kinase C brain isozyme 0.1092 0.1664 0.1664
Echinococcus multilocularis ephrin type A receptor 4 A 0.0476 0.0586 0.0585
Echinococcus granulosus dual specificity 0.0169 0.0048 0.0048
Trichomonas vaginalis CAMK family protein kinase 0.0264 0.0214 0.1021
Brugia malayi Protein kinase domain containing protein 0.1813 0.2926 0.2925
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0318 0.0309 0.0309
Giardia lamblia Kinase, NEK 0.0538 0.0694 0.3445
Echinococcus multilocularis tyrosine protein kinase csk 0.0149 0.0012 0.0011
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0889 0.1309 0.1308
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0309 0.0293 0.0292
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0574 0.0757 0.0756
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0625 0.0847 0.0847
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0166 0.0043 0.0209
Brugia malayi Protein kinase domain containing protein 0.0578 0.0764 0.0763
Giardia lamblia Kinase, CMGC SRPK 0.0166 0.0043 0.0155
Trichomonas vaginalis CMGC family protein kinase 0.0173 0.0055 0.0265
Trypanosoma brucei polo-like protein kinase 0.1279 0.1991 0.9507
Schistosoma mansoni tyrosine kinase 0.1476 0.2336 0.2331
Brugia malayi Protein kinase domain containing protein 0.0566 0.0743 0.0742
Brugia malayi Raf kinase 0.0149 0.0012 0.0011
Trichomonas vaginalis CMGC family protein kinase 0.0321 0.0314 0.15
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0179 0.0066 0.0065
Trichomonas vaginalis CMGC family protein kinase 0.0169 0.0048 0.023
Trichomonas vaginalis AGC family protein kinase 0.0149 0.0012 0.0057
Entamoeba histolytica protein kinase domain containing protein 0.0149 0.0012 0.0057
Brugia malayi Immunoglobulin I-set domain containing protein 0.0152 0.0019 0.0018
Echinococcus granulosus tyrosine protein kinase shark 0.0278 0.0238 0.0237
Schistosoma mansoni serine/threonine protein kinase 0.0252 0.0193 0.0187
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0149 0.0012 0.0057
Loa Loa (eye worm) hypothetical protein 0.0152 0.0019 0.0018
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0264 0.0214 0.1074
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0243 0.0178 0.0177
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Schistosoma mansoni serine/threonine protein kinase 0.036 0.0382 0.0376
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.036 0.0382 0.0381
Trichomonas vaginalis CAMK family protein kinase 0.0264 0.0214 0.1021
Entamoeba histolytica protein kinase, putative 0.0149 0.0012 0.0057
Echinococcus multilocularis tyrosine protein kinase csk 0.0149 0.0012 0.0011
Schistosoma mansoni protein kinase 0.0782 0.1121 0.1116
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0321 0.0313 0.0312
Trichomonas vaginalis protein tyrosine kinase, putative 0.0149 0.0012 0.0057
Echinococcus multilocularis 0.0718 0.1009 0.1009
Loa Loa (eye worm) hypothetical protein 0.0182 0.007 0.0069
Brugia malayi Immunoglobulin I-set domain containing protein 0.0179 0.0066 0.0065
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0243 0.0178 0.085
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0277 0.0237 0.0236
Trichomonas vaginalis STE family protein kinase 0.0346 0.0358 0.1708
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0516 0.0655 0.0654
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0149 0.0012 0.0057
Entamoeba histolytica tyrosine kinase, putative 0.0149 0.0012 0.0057
Loa Loa (eye worm) hypothetical protein 0.0182 0.007 0.0069
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0039 0.0187
Brugia malayi Protein kinase domain containing protein 0.0149 0.0012 0.0011
Echinococcus multilocularis mitogen activated protein kinase 0.0321 0.0314 0.0314
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0166 0.0042 0.0042
Schistosoma mansoni serine/threonine protein kinase 0.0222 0.0141 0.0135
Brugia malayi Protein kinase domain containing protein 0.1124 0.1721 0.172
Schistosoma mansoni tyrosine protein kinase 0.0149 0.0012 0.0006
Brugia malayi RhoGEF domain containing protein 0.0182 0.007 0.0069
Brugia malayi Casein kinase II, alpha chain 0.0455 0.0548 0.0547
Entamoeba histolytica diacylglycerol kinase, putative 0.0182 0.007 0.0336
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0149 0.0012 0.0057
Entamoeba histolytica protein kinase domain containing protein 0.0578 0.0764 0.365
Plasmodium falciparum calcium-dependent protein kinase 1 0.0296 0.0269 0.2674
Loa Loa (eye worm) hypothetical protein 0.0532 0.0683 0.0682
Echinococcus granulosus integrin linked protein kinase 0.0149 0.0012 0.0011
Trypanosoma brucei cdc2-related kinase 3 0.0508 0.0642 0.3066
Trichomonas vaginalis CAMK family protein kinase 0.1279 0.1991 0.9507
Schistosoma mansoni protein kinase 0.052 0.0663 0.0657
Entamoeba histolytica tyrosine kinase, putative 0.0149 0.0012 0.0057
Trichomonas vaginalis protein kinase atn1, putative 0.0149 0.0012 0.0057
Trichomonas vaginalis AGC family protein kinase 0.0312 0.0298 0.1422
Onchocerca volvulus 0.0586 0.0779 0.2123
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Entamoeba histolytica serine/threonine kinase, putative 0.0149 0.0012 0.0057
Brugia malayi Immunoglobulin I-set domain containing protein 0.2561 0.4236 0.4236
Brugia malayi hypothetical protein 0.0355 0.0373 0.0372
Onchocerca volvulus 0.0149 0.0012 0.003
Echinococcus multilocularis Protein kinase C, brain isozyme 0.1092 0.1664 0.1664
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.1279 0.1991 0.199
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0606 0.0813 0.0812
Entamoeba histolytica tyrosine kinase, putative 0.0149 0.0012 0.0057
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0508 0.0642 0.0641
Loa Loa (eye worm) TK/FER protein kinase 0.0149 0.0012 0.0011
Entamoeba histolytica protein kinase domain containing protein 0.0149 0.0012 0.0057
Loa Loa (eye worm) raf kinase 0.0182 0.007 0.0069
Echinococcus multilocularis myotubularin protein 13 0.0212 0.0124 0.0123
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0169 0.0048 0.0242
Entamoeba histolytica receptor protein kinase, putative 0.0149 0.0012 0.0057
Brugia malayi Protein kinase domain containing protein 0.033 0.033 0.0329
Echinococcus multilocularis FL cytokine receptor 0.0149 0.0012 0.0011
Entamoeba histolytica protein kinase, putative 0.0169 0.0048 0.023
Trichomonas vaginalis conserved hypothetical protein 0.015 0.0014 0.0067
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0538 0.0694 0.34
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.387 0.6528 0.6528
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0264 0.0214 0.1074
Loa Loa (eye worm) hypothetical protein 0.0586 0.0779 0.0778
Schistosoma mansoni protein kinase 0.0903 0.1332 0.1327
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0179 0.0066 0.0065
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Entamoeba histolytica hypothetical protein 0.0149 0.0014 0.0065
Loa Loa (eye worm) hypothetical protein 0.0505 0.0637 0.0636
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0252 0.0193 0.0192
Echinococcus multilocularis 0.0243 0.0177 0.0176
Brugia malayi serine/threonine-protein kinase PAK 7 0.1115 0.1704 0.1703
Loa Loa (eye worm) hypothetical protein 0.0182 0.007 0.0069
Echinococcus multilocularis protein kinase 0.0149 0.0012 0.0011
Schistosoma mansoni serine/threonine protein kinase 0.0701 0.0979 0.0974
Schistosoma mansoni serine/threonine protein kinase 0.0201 0.0104 0.0098
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0039 0.0187
Echinococcus multilocularis c Jun NH2 terminal kinase 0.5853 1 1
Echinococcus multilocularis hemicentin 1 0.0152 0.0019 0.0018
Entamoeba histolytica protein kinase domain containing protein 0.0149 0.0012 0.0057
Loa Loa (eye worm) hypothetical protein 0.1563 0.2489 0.2488
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0962 0.1436 0.1436
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0249 0.0187 0.0187
Schistosoma mansoni serine/threonine protein kinase 0.1092 0.1664 0.1659
Loa Loa (eye worm) hypothetical protein 0.0149 0.0012 0.0011
Schistosoma mansoni serine/threonine protein kinase 0.0222 0.0141 0.0135
Echinococcus granulosus NCK adaptor protein 0.0234 0.0162 0.0162
Entamoeba histolytica hypothetical protein 0.0149 0.0014 0.0065
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0305 0.0286 0.0285
Echinococcus granulosus calcium activated potassium channel 0.0502 0.0631 0.0631
Plasmodium vivax protein kinase Crk2 0.0508 0.0642 0.6372
Loa Loa (eye worm) hypothetical protein 0.0404 0.0459 0.0458
Schistosoma mansoni cell adhesion molecule 0.0179 0.0066 0.006
Echinococcus multilocularis casein kinase I alpha 0.0309 0.0293 0.0293
Trichomonas vaginalis conserved hypothetical protein 0.0149 0.0012 0.0057
Schistosoma mansoni tyrosine kinase 0.0149 0.0012 0.0006
Schistosoma mansoni serine/threonine protein kinase 0.0889 0.1309 0.1304
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0164 0.0039 0.0189
Entamoeba histolytica serine/threonine kinase, putative 0.0149 0.0012 0.0057
Schistosoma mansoni serine/threonine protein kinase 0.0962 0.1436 0.1431
Entamoeba histolytica tyrosine kinase, putative 0.0149 0.0012 0.0057
Schistosoma mansoni serine/threonine protein kinase 0.0502 0.0631 0.0625
Schistosoma mansoni protein kinase 0.0309 0.0293 0.0287
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0149 0.0012 0.0057
Loa Loa (eye worm) TK/DDR protein kinase 0.0149 0.0012 0.0011
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Trichomonas vaginalis CMGC family protein kinase 0.0169 0.0048 0.023
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0149 0.0012 0.0011
Entamoeba histolytica hypothetical protein 0.0578 0.0764 0.365
Brugia malayi Protein kinase domain containing protein 0.0312 0.0298 0.0297
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0632 0.0858 0.4098
Echinococcus multilocularis dual specificity protein kinase clk2 0.0243 0.0178 0.0177
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0149 0.0012 0.0057
Echinococcus multilocularis NCK adaptor protein 0.0239 0.0171 0.017
Schistosoma mansoni serine/threonine protein kinase 0.0243 0.0177 0.0171
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0508 0.0642 0.0641
Trichomonas vaginalis CAMK family protein kinase 0.0589 0.0784 0.3743
Schistosoma mansoni serine/threonine protein kinase 0.036 0.0382 0.0376
Entamoeba histolytica hypothetical protein, conserved 0.0149 0.0012 0.0057
Entamoeba histolytica protein kinase domain containing protein 0.0149 0.0012 0.0057
Trichomonas vaginalis CAMK family protein kinase 0.0149 0.0012 0.0057
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0298 0.0273 0.0272
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Brugia malayi serine/threonine-protein kinase plk-2 0.1279 0.1991 0.199
Entamoeba histolytica tyrosine kinase, putative 0.0149 0.0012 0.0057
Plasmodium falciparum protein serine/threonine kinase-1 0.0243 0.0178 0.1766
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0149 0.0012 0.003
Echinococcus granulosus serine/threonine protein kinase 0.0748 0.1061 0.1061
Schistosoma mansoni serine/threonine protein kinase 0.0149 0.0012 0.0006
Entamoeba histolytica tyrosine kinase, putative 0.0149 0.0012 0.0057
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0238 0.0168 0.0168
Schistosoma mansoni serine/threonine protein kinase 0.0215 0.0128 0.0122
Trichomonas vaginalis CAMK family protein kinase 0.0169 0.0048 0.0232
Trichomonas vaginalis AGC family protein kinase 0.0312 0.0298 0.1422
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Leishmania major protein kinase, putative 0.0296 0.0269 0.1353
Loa Loa (eye worm) hypothetical protein 0.0405 0.046 0.0459
Trichomonas vaginalis CAMK family protein kinase 0.0169 0.0048 0.0232
Echinococcus granulosus N chimaerin 0.0311 0.0296 0.0296
Loa Loa (eye worm) hypothetical protein 0.0385 0.0426 0.0425
Entamoeba histolytica protein kinase domain containing protein 0.0149 0.0012 0.0057
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0149 0.0012 0.003
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0701 0.0979 0.0979
Entamoeba histolytica protein kinase, putative 0.0149 0.0012 0.0057
Echinococcus granulosus serine:threonine kinase SAD 1 0.0264 0.0214 0.0213
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0508 0.0642 0.3146
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Trichomonas vaginalis AGC family protein kinase 0.1338 0.2094 1
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0225 0.0146 0.0146
Echinococcus granulosus serine:threonine protein kinase 0.0571 0.0752 0.0751
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0707 0.099 0.0989
Plasmodium falciparum serine/threonine protein kinase 0.0166 0.0043 0.0423
Echinococcus granulosus serine threonine protein kinase nrc 0.0717 0.1007 0.1007
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0255 0.0198 0.0197
Echinococcus granulosus casein kinase I delta 0.0309 0.0293 0.0293
Echinococcus granulosus myotubularin protein 13 0.0212 0.0124 0.0123
Trichomonas vaginalis AGC family protein kinase 0.0632 0.0858 0.4098
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0264 0.0214 0.2122
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.026 0.0206 0.0986
Loa Loa (eye worm) AGC/PKA protein kinase 0.036 0.0382 0.0381
Entamoeba histolytica protein kinase, putative 0.024 0.0172 0.0823
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Giardia lamblia Kinase, STE STE20 0.0346 0.0358 0.1747
Loa Loa (eye worm) hypothetical protein 0.0264 0.0214 0.0213
Loa Loa (eye worm) TK protein kinase 0.0149 0.0012 0.0011
Leishmania major protein kinase A catalytic subunit isoform 2 0.036 0.0382 0.1919
Loa Loa (eye worm) protein kinase domain-containing protein 0.0149 0.0012 0.0011
Brugia malayi Protein kinase domain containing protein 0.0902 0.1331 0.133
Schistosoma mansoni roundabout 0.0152 0.0019 0.0013
Schistosoma mansoni serine/threonine protein kinase 0.0149 0.0012 0.0006
Echinococcus granulosus serine:threonine protein kinase N2 0.0843 0.1228 0.1228
Schistosoma mansoni serine/threonine protein kinase 0.0498 0.0623 0.0618
Trichomonas vaginalis CMGC family protein kinase 0.0169 0.0048 0.023
Echinococcus multilocularis neuroglian 0.0179 0.0066 0.0065
Brugia malayi hypothetical protein 0.0153 0.0019 0.0018
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0188 0.0082 0.0081
Schistosoma mansoni hypothetical protein 0.0391 0.0436 0.0431
Trichomonas vaginalis CAMK family protein kinase 0.0169 0.0048 0.0232
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0039 0.0187
Schistosoma mansoni protein kinase 0.0227 0.015 0.0144
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0346 0.0358 0.0357
Trypanosoma brucei SNF1-related protein kinases, putative 0.0264 0.0214 0.1021
Schistosoma mansoni serine/threonine protein kinase 0.0264 0.0214 0.0208
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0296 0.0269 0.132
Trichomonas vaginalis AGC family protein kinase 0.0312 0.0298 0.1422
Schistosoma mansoni tyrosine kinase 0.0149 0.0012 0.0006
Toxoplasma gondii protein kinase domain-containing protein 0.0149 0.0012 0.0058
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0296 0.0269 0.2674
Brugia malayi Protein kinase domain containing protein 0.0166 0.0043 0.0042
Schistosoma mansoni serine/threonine protein kinase 0.0305 0.0286 0.028
Plasmodium falciparum glycogen synthase kinase 3 0.0554 0.0722 0.7165
Brugia malayi Fes/CIP4 homology domain containing protein 0.0184 0.0074 0.0073
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0149 0.0012 0.0057
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Loa Loa (eye worm) hypothetical protein 0.0397 0.0447 0.0446
Brugia malayi Immunoglobulin I-set domain containing protein 0.0179 0.0066 0.0065
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0309 0.0293 0.0292
Loa Loa (eye worm) TK/FER protein kinase 0.0278 0.0238 0.0237
Echinococcus granulosus fibroblast growth factor receptor 4 0.0968 0.1447 0.1447
Echinococcus multilocularis cyclin dependent kinase 1 0.0508 0.0642 0.0641
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0312 0.0298 0.0297
Loa Loa (eye worm) hypothetical protein 0.0391 0.0436 0.0435
Schistosoma mansoni cell adhesion molecule 0.0152 0.0019 0.0013
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0048 0.0232
Brugia malayi Immunoglobulin I-set domain containing protein 0.0355 0.0373 0.0372
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.1609 0.257 0.2569
Brugia malayi Protein kinase c protein 2 0.0502 0.0632 0.0631
Onchocerca volvulus 0.0405 0.046 0.1254
Loa Loa (eye worm) hypothetical protein 0.0609 0.0818 0.0817
Plasmodium vivax tyrosine kinase-like protein, putative 0.0149 0.0012 0.0118
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0625 0.0847 0.0847
Toxoplasma gondii diacylglycerol kinase, putative 0.0182 0.007 0.0344
Trichomonas vaginalis conserved hypothetical protein 0.0149 0.0012 0.0057
Loa Loa (eye worm) hypothetical protein 0.0405 0.046 0.0459
Loa Loa (eye worm) TK/FAK protein kinase 0.0709 0.0994 0.0993
Brugia malayi Protein kinase domain containing protein 0.0278 0.0238 0.0237
Trichomonas vaginalis STE family protein kinase 0.0346 0.0358 0.1708
Echinococcus granulosus neuroglian 0.0405 0.0461 0.046
Echinococcus multilocularis dual specificity mitogen activated protein 0.0192 0.0089 0.0088
Onchocerca volvulus 0.0215 0.0128 0.0347
Plasmodium falciparum tyrosine kinase-like protein 0.0149 0.0012 0.0118
Onchocerca volvulus 0.0278 0.0238 0.0646
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0149 0.0012 0.0011
Plasmodium falciparum serine/threonine protein kinase, putative 0.0632 0.0858 0.8517
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0039 0.0187
Schistosoma mansoni nephrin 0.0179 0.0066 0.006
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0508 0.0642 0.3225
Echinococcus multilocularis death associated protein kinase 1 0.3483 0.5851 0.5851
Loa Loa (eye worm) hypothetical protein 0.0152 0.0019 0.0018
Brugia malayi Variant SH3 domain containing protein 0.0166 0.0043 0.0042
Echinococcus granulosus insulin growth factor 1 receptor beta 0.184 0.2973 0.2973
Echinococcus multilocularis cyclin dependent kinase 0.0508 0.0642 0.0641
Brugia malayi Protein kinase domain containing protein 0.1338 0.2094 0.2093
Echinococcus multilocularis calcium dependent protein kinase 0.0184 0.0075 0.0074
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0968 0.1447 0.1447
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0717 0.1007 1
Echinococcus multilocularis protein kinase 0.0149 0.0012 0.0011
Echinococcus granulosus tyrosine protein kinase 0.0411 0.0472 0.0471
Entamoeba histolytica hypothetical protein 0.0145 0.0006 0.0028
Entamoeba histolytica protein kinase domain containing protein 0.0554 0.0722 0.3448
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0717 0.1007 0.5061
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0748 0.1062 0.1061
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Trichomonas vaginalis STE family protein kinase 0.0149 0.0012 0.0057
Toxoplasma gondii protein kinase 0.0149 0.0012 0.0058
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0149 0.0012 0.0011
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Echinococcus granulosus cyclin dependent kinase 5 0.0508 0.0642 0.0641
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0264 0.0214 0.0213
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0486 0.0603 0.0603
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0201 0.0104 0.0103
Brugia malayi Furin-like cysteine rich region family protein 0.2485 0.4103 0.4103
Brugia malayi Protein kinase domain containing protein 0.0278 0.0238 0.0237
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0039 0.0187
Echinococcus multilocularis unc 13 (munc13) 0.0188 0.0082 0.0081
Echinococcus granulosus c-Jun N-terminal kinases 0.5853 1 1
Loa Loa (eye worm) SRC-1 0.0625 0.0847 0.0846
Echinococcus multilocularis tyrosine protein kinase pr2 0.0149 0.0012 0.0011
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0962 0.1436 0.1436
Echinococcus multilocularis twitchin 0.0188 0.0081 0.008
Entamoeba histolytica protein kinase, putative 0.0391 0.0436 0.2085
Entamoeba histolytica protein kinase, putative 0.0149 0.0012 0.0057
Entamoeba histolytica cell division protein kinase 2, putative 0.0508 0.0642 0.3066
Schistosoma mansoni protein kinase 0.0455 0.0548 0.0543
Loa Loa (eye worm) TK/CSK protein kinase 0.0149 0.0012 0.0011
Trichomonas vaginalis AGC family protein kinase 0.0701 0.0979 0.4677
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Trichomonas vaginalis CAMK family protein kinase 0.0296 0.0269 0.1287
Leishmania major protein kinase, putative 0.0243 0.0178 0.0894
Brugia malayi Peroxidasin 0.0153 0.0021 0.002
Brugia malayi Immunoglobulin I-set domain containing protein 0.0152 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.0235 0.0163 0.0162
Loa Loa (eye worm) hypothetical protein 0.0152 0.0019 0.0018
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0149 0.0012 0.0011
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0176 0.0059 0.0059
Brugia malayi hypothetical protein 0.0149 0.0012 0.0011
Trichomonas vaginalis CMGC family protein kinase 0.0455 0.0548 0.2618
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0201 0.0104 0.052
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0305 0.0286 0.0285
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0929 0.1379 0.1378
Schistosoma mansoni serine/threonine protein kinase 0.0243 0.0178 0.0172
Schistosoma mansoni diacylglycerol kinase theta 0.0182 0.007 0.0064
Trichomonas vaginalis CAMK family protein kinase 0.0169 0.0048 0.0232
Trichomonas vaginalis AGC family protein kinase 0.0723 0.1019 0.4864
Brugia malayi Ras association domain family 1 isoform A 0.0182 0.007 0.0069
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0311 0.0296 0.0296
Entamoeba histolytica serine/threonine kinase, putative 0.0149 0.0012 0.0057
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0149 0.0012 0.0011
Entamoeba histolytica protein kinase, putative 0.0149 0.0012 0.0057
Trichomonas vaginalis AGC family protein kinase 0.1338 0.2094 1
Loa Loa (eye worm) TK/FER protein kinase 0.0278 0.0238 0.0237
Entamoeba histolytica casein kinase, putative 0.0455 0.0548 0.2618
Loa Loa (eye worm) hypothetical protein 0.0149 0.0012 0.0011
Trichomonas vaginalis CMGC family protein kinase 0.0508 0.0642 0.3066
Entamoeba histolytica ankyrin repeat protein 0.0149 0.0012 0.0057
Brugia malayi integrin-linked kinase 0.0149 0.0012 0.0011
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.036 0.0382 0.1872
Loa Loa (eye worm) hypothetical protein 0.0732 0.1034 0.1033
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0104 0.0497
Trichomonas vaginalis CAMK family protein kinase 0.0264 0.0214 0.1021
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.1115 0.1704 0.1703
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0312 0.0298 0.0297
Schistosoma mansoni protein tyrosine kinase 0.0149 0.0012 0.0006
Loa Loa (eye worm) hypothetical protein 0.0219 0.0134 0.0133
Brugia malayi Protein kinase domain containing protein 0.0149 0.0012 0.0011
Brugia malayi Serine/threonine-protein kinase SULU 0.0318 0.0309 0.0308
Echinococcus granulosus dual specificity 0.0578 0.0764 0.0764
Schistosoma mansoni titin 0.0152 0.0019 0.0013
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0296 0.0269 0.132
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0182 0.007 0.0069
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0962 0.1436 0.1436
Schistosoma mansoni tyrosine kinase 0.0383 0.0422 0.0417
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0238 0.0168 0.0167
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0149 0.0012 0.0057
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Loa Loa (eye worm) IKK protein kinase 0.1124 0.1721 0.172
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0632 0.0858 0.4098
Entamoeba histolytica protein kinase , putative 0.0632 0.0858 0.4098
Brugia malayi Variant SH3 domain containing protein 0.0234 0.0162 0.0161
Loa Loa (eye worm) CAMK/CAMKL/PASK protein kinase 0.0161 0.0033 0.0032
Echinococcus multilocularis tyrosine protein kinase shark 0.0278 0.0238 0.0237
Entamoeba histolytica protein kinase domain containing protein 0.0149 0.0012 0.0057
Schistosoma mansoni tyrosine kinase 0.0149 0.0012 0.0006
Trichomonas vaginalis CAMK family protein kinase 0.0169 0.0048 0.0232
Entamoeba histolytica protein kinase domain containing protein 0.0149 0.0012 0.0057
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.5853 1 1
Schistosoma mansoni tyrosine kinase 0.1476 0.2336 0.2331
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0149 0.0012 0.0011
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0296 0.0269 0.0269
Echinococcus granulosus Immunoglobulin 0.0328 0.0326 0.0326
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0296 0.0269 0.2674
Schistosoma mansoni tyrosine kinase 0.0149 0.0012 0.0006
Brugia malayi Protein kinase domain containing protein 0.0149 0.0012 0.0011
Schistosoma mansoni serine/threonine protein kinase 0.0201 0.0104 0.0098
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0243 0.0178 0.0894
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Giardia lamblia Kinase, CDC7 0.0173 0.0055 0.022
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0252 0.0193 0.0192
Plasmodium falciparum NIMA related kinase 1 0.0538 0.0694 0.6885
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0039 0.0187
Entamoeba histolytica protein kinase, putative 0.0346 0.0358 0.1708
Echinococcus granulosus titin 0.0215 0.0128 0.0127
Brugia malayi Immunoglobulin I-set domain containing protein 0.0152 0.0019 0.0018
Echinococcus multilocularis peroxidasin 0.0153 0.0021 0.002
Giardia lamblia Kinase, CMGC CK2 0.0455 0.0548 0.2711
Entamoeba histolytica serine/threonine kinase, putative 0.0149 0.0012 0.0057
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Onchocerca volvulus 0.0149 0.0012 0.003
Echinococcus granulosus raf serine:threonine protein kinase 0.033 0.033 0.033
Echinococcus granulosus casein kinase ii subunit alpha 0.0455 0.0548 0.0548
Trichomonas vaginalis CAMK family protein kinase 0.0264 0.0214 0.1021
Loa Loa (eye worm) TK protein kinase 0.052 0.0662 0.0661
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0192 0.0089 0.0088
Echinococcus granulosus nervana 2 0.0606 0.0813 0.0812
Brugia malayi Protein kinase domain containing protein 0.0732 0.1034 0.1033
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.1131 0.1733 0.1733
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.1279 0.1991 0.199
Echinococcus granulosus mitogen activated protein kinase 3 0.0321 0.0314 0.0314
Trichomonas vaginalis CAMK family protein kinase 0.0264 0.0214 0.1021
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Echinococcus granulosus cyclin dependent kinase 19 0.0255 0.0198 0.0197
Loa Loa (eye worm) hypothetical protein 0.0329 0.0328 0.0327
Schistosoma mansoni protein kinase 0.0346 0.0358 0.0352
Echinococcus granulosus natriuretic peptide receptor 1 0.0149 0.0012 0.0011
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0297 0.0272 0.0271
Giardia lamblia Kinase, CMGC GSK 0.0554 0.0722 0.3588
Schistosoma mansoni serine/threonine protein kinase 0.033 0.033 0.0325
Echinococcus granulosus dual specificity 0.0169 0.0048 0.0048
Brugia malayi intracellular kinase 0.0554 0.0722 0.0721
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0222 0.0141 0.0141
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0554 0.0722 0.0721
Trichomonas vaginalis CAMK family protein kinase 0.1279 0.1991 0.9507
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.036 0.0382 0.1919
Loa Loa (eye worm) hypothetical protein 0.0571 0.0752 0.0751
Echinococcus granulosus MAP kinase activated protein kinase 2 0.1783 0.2873 0.2873
Leishmania major protein kinase A catalytic subunit isoform 1 0.036 0.0382 0.1919
Trichomonas vaginalis CMGC family protein kinase 0.0321 0.0314 0.15
Brugia malayi cell division control protein 2 homolog 0.0508 0.0642 0.0641
Echinococcus granulosus tyrosine protein kinase Srms 0.0278 0.0238 0.0237
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0578 0.0764 0.3839
Echinococcus multilocularis expressed conserved protein 0.0222 0.0141 0.0141
Trichomonas vaginalis CAMK family protein kinase 0.0264 0.0214 0.1021
Entamoeba histolytica protein kinase, putative 0.0632 0.0858 0.4098
Trichomonas vaginalis TK family protein kinase 0.015 0.0014 0.0067
Echinococcus granulosus TGF-beta receptor type-1 0.019 0.0084 0.0084
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0149 0.0012 0.0057
Trichomonas vaginalis CMGC family protein kinase 0.0169 0.0048 0.023
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0192 0.0089 0.0424
Loa Loa (eye worm) thyroid receptor interactor 0.0184 0.0074 0.0073
Entamoeba histolytica protein kinase, putative 0.0701 0.0979 0.4677
Onchocerca volvulus Serine\/threonine kinase homolog 0.0255 0.0198 0.0538
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Echinococcus granulosus tyrosine protein kinase ABL1 0.1135 0.174 0.1739
Loa Loa (eye worm) hypothetical protein 0.0182 0.007 0.0069
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0166 0.0042 0.0202
Loa Loa (eye worm) RGC/RGC protein kinase 0.0149 0.0012 0.0011
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.1131 0.1733 0.1732
Echinococcus granulosus casein kinase I alpha 0.0309 0.0293 0.0293
Trichomonas vaginalis TKL family protein kinase 0.015 0.0014 0.0067
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0633 0.086 0.4108
Loa Loa (eye worm) TK/FER protein kinase 0.0278 0.0238 0.0237
Onchocerca volvulus 0.0149 0.0012 0.003
Schistosoma mansoni tyrosine kinase 0.0278 0.0238 0.0232
Schistosoma mansoni unc-13 (munc13) 0.0188 0.0082 0.0076
Brugia malayi Prion-like- 0.0152 0.0019 0.0018
Entamoeba histolytica ankyrin repeat protein 0.0149 0.0012 0.0057
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0149 0.0012 0.0006
Onchocerca volvulus 0.0278 0.0238 0.0646
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.1131 0.1733 0.1733
Trichomonas vaginalis AGC family protein kinase 0.0632 0.0858 0.4098
Leishmania major hypothetical protein, conserved 0.0149 0.0012 0.006
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0048 0.0232
Brugia malayi diacylglycerol kinase 0.0182 0.007 0.0069
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0578 0.0764 0.365
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0698 0.0973 0.0972
Echinococcus granulosus titin 0.0215 0.0128 0.0127
Echinococcus granulosus Rac GTPase activating protein 1 0.0182 0.007 0.007
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.052 0.0663 0.0662
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0164 0.0039 0.0187
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0215 0.0128 0.0127
Loa Loa (eye worm) camk/dcamkl protein kinase 0.024 0.0172 0.0171
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0149 0.0012 0.0011
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0346 0.0358 0.0357
Echinococcus multilocularis tyrosine kinase 0.0149 0.0012 0.0011
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0707 0.099 0.0989
Echinococcus granulosus aurora kinase A 0.0632 0.0858 0.0858
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0048 0.0232
Loa Loa (eye worm) AGC/PKG protein kinase 0.0222 0.0141 0.014
Echinococcus multilocularis titin 0.0215 0.0128 0.0127
Onchocerca volvulus 0.2009 0.3269 0.8923
Echinococcus granulosus unc 13 munc13 0.0188 0.0082 0.0081
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0554 0.0722 0.0721
Echinococcus granulosus activin receptor type 0.0661 0.091 0.0909
Onchocerca volvulus 0.0149 0.0012 0.003
Brugia malayi Protein kinase domain containing protein 0.0255 0.0198 0.0197
Echinococcus multilocularis c src tyrosine kinase 0.0383 0.0422 0.0422
Echinococcus multilocularis dual specificity 0.0169 0.0048 0.0048
Schistosoma mansoni serine/threonine protein kinase 0.0843 0.1228 0.1223
Plasmodium vivax glycogen synthase kinase 3, putative 0.0554 0.0722 0.7165
Trypanosoma cruzi casein kinase, putative 0.0309 0.0293 0.1472
Loa Loa (eye worm) TK/ABL protein kinase 0.1135 0.174 0.1739
Loa Loa (eye worm) hypothetical protein 0.0617 0.0832 0.0831
Entamoeba histolytica protein kinase, putative 0.0149 0.0012 0.0057
Brugia malayi Protein kinase domain containing protein 0.0732 0.1034 0.1033
Entamoeba histolytica hypothetical protein 0.0149 0.0012 0.0057
Echinococcus multilocularis epidermal growth factor receptor 0.2485 0.4103 0.4103
Trichomonas vaginalis AGC family protein kinase 0.1338 0.2094 1
Plasmodium falciparum casein kinase 2, alpha subunit 0.0455 0.0548 0.5442
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0149 0.0012 0.0006
Trichomonas vaginalis CAMK family protein kinase 0.0264 0.0214 0.1021
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0286 0.0253 0.0252
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0152 0.0019 0.0049
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0149 0.0012 0.0057
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0166 0.0043 0.0214
Trichomonas vaginalis CK1 family protein kinase 0.0309 0.0293 0.14
Echinococcus multilocularis protein kinase c eta type 0.0182 0.007 0.007
Schistosoma mansoni serine/threonine protein kinase 0.0297 0.0272 0.0266
Loa Loa (eye worm) TK/FER protein kinase 0.0149 0.0012 0.0011
Giardia lamblia Kinase, CMGC CDK 0.0508 0.0642 0.3184
Echinococcus granulosus protein kinase c iota type 0.1307 0.2041 0.204
Echinococcus granulosus Glutaredoxin protein 5 0.0606 0.0813 0.0812
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0578 0.0764 0.0763
Loa Loa (eye worm) TK/FER protein kinase 0.0149 0.0012 0.0011
Trypanosoma brucei aurora B kinase 0.0632 0.0858 0.4098
Echinococcus granulosus tyrosine protein kinase csk 0.0149 0.0012 0.0011
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0149 0.0012 0.0057
Schistosoma mansoni tyrosine kinase 0.1813 0.2926 0.2922
Loa Loa (eye worm) hypothetical protein 0.0594 0.0791 0.079
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0592 0.0789 0.0788
Loa Loa (eye worm) hypothetical protein 0.0166 0.0042 0.0041
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0166 0.0042 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0149 0.0012 0.0057
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0039 0.0187
Echinococcus granulosus casein kinase i 0.0309 0.0293 0.0293
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Entamoeba histolytica protein kinase, putative 0.0149 0.0012 0.0057
Loa Loa (eye worm) RasGEF domain-containing protein 0.0182 0.007 0.0069
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0188 0.0082 0.0081
Trichomonas vaginalis CAMK family protein kinase 0.0264 0.0214 0.1021
Entamoeba histolytica protein kinase, putative 0.0149 0.0014 0.0065
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0243 0.0178 0.0894
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0192 0.0089 0.0446
Onchocerca volvulus Serine\/threonine kinase homolog 0.1279 0.1991 0.5432
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0328 0.0326 0.0321
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0201 0.0104 0.0103
Echinococcus multilocularis mitogen activated protein kinase 14 0.0633 0.086 0.086
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0717 0.1007 0.1007
Loa Loa (eye worm) TK/EPH protein kinase 0.0566 0.0743 0.0742
Echinococcus multilocularis nervana 2 0.0606 0.0813 0.0812
Trypanosoma cruzi casein kinase II, putative 0.0455 0.0548 0.2754
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0048 0.0232
Brugia malayi protein unc-22 0.0215 0.0128 0.0127
Echinococcus granulosus tyrosine protein kinase Fyn 0.0625 0.0847 0.0847
Brugia malayi C-terminal src kinase protein 1 0.0149 0.0012 0.0011
Entamoeba histolytica hypothetical protein 0.0149 0.0012 0.0057
Brugia malayi Protein kinase domain containing protein 0.0243 0.0177 0.0176
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0149 0.0012 0.0057
Brugia malayi Immunoglobulin I-set domain containing protein 0.0152 0.0019 0.0018
Echinococcus multilocularis casein kinase I delta 0.0309 0.0293 0.0293
Onchocerca volvulus 0.0278 0.0238 0.0646
Trichomonas vaginalis CMGC family protein kinase 0.0169 0.0048 0.023
Echinococcus granulosus growth factor receptor bound protein 2 0.0239 0.0171 0.017
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Entamoeba histolytica protein kinase domain containing protein 0.0455 0.0548 0.2618
Loa Loa (eye worm) TK protein kinase 0.0411 0.0472 0.0471
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0039 0.0187
Brugia malayi phosphoinositide-dependent protein kinase I 0.0312 0.0298 0.0297
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0701 0.0979 0.0979
Trichomonas vaginalis CAMK family protein kinase 0.0264 0.0214 0.1021
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0376 0.0411 0.041
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0325 0.0321 0.1532
Schistosoma mansoni serine/threonine protein kinase 0.5853 1 1
Loa Loa (eye worm) hypothetical protein 0.0212 0.0124 0.0123
Echinococcus granulosus kinase suppressor of Ras 1 0.0149 0.0012 0.0011
Brugia malayi WH1 domain containing protein 0.0145 0.0006 0.0005
Echinococcus multilocularis casein kinase I alpha 0.0309 0.0293 0.0293
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0554 0.0722 0.0721
Schistosoma mansoni protein kinase C mu 0.0698 0.0973 0.0968
Trichomonas vaginalis CMGC family protein kinase 0.0455 0.0548 0.2618
Echinococcus granulosus NDR protein kinase 0.0701 0.0979 0.0979
Entamoeba histolytica protein kinase domain containing protein 0.0149 0.0012 0.0057
Brugia malayi Tyrosine-protein kinase abl-1 0.0711 0.0997 0.0996
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0149 0.0012 0.0011
Onchocerca volvulus Tyrosine kinase homolog 0.2234 0.3664 1
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Schistosoma mansoni serine/threonine protein kinase 0.0929 0.1379 0.1373
Echinococcus granulosus roundabout 2 0.0507 0.064 0.064
Echinococcus granulosus serine:threonine protein kinase 0.0571 0.0752 0.0751
Trichomonas vaginalis CMGC family protein kinase 0.0455 0.0548 0.2618
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0201 0.0104 0.0103
Onchocerca volvulus 0.0225 0.0146 0.0395
Trypanosoma cruzi protein kinase, putative 0.0149 0.0012 0.006
Brugia malayi protein-tyrosine kinase 0.052 0.0662 0.0661
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0508 0.0642 0.0641
Brugia malayi Protein kinase domain containing protein 0.0278 0.0238 0.0237
Loa Loa (eye worm) TK protein kinase 0.0149 0.0012 0.0011
Schistosoma mansoni protein kinase 0.0149 0.0012 0.0006
Brugia malayi Protein kinase domain containing protein 0.0149 0.0012 0.0011
Entamoeba histolytica hypothetical protein 0.0149 0.0014 0.0065
Schistosoma mansoni kinase 0.1263 0.1963 0.1959
Echinococcus multilocularis dual specificity 0.0578 0.0764 0.0764
Brugia malayi serine/threonine kinase 12 0.0632 0.0858 0.0857
Echinococcus granulosus activated cdc42 kinase 1 0.033 0.033 0.033
Trypanosoma cruzi protein kinase, putative 0.0149 0.0012 0.006
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0243 0.0178 0.0894
Echinococcus multilocularis protein tyrosine kinase 0.0703 0.0982 0.0982
Schistosoma mansoni tyrosine kinase 0.0149 0.0012 0.0006
Trypanosoma cruzi polo-like protein kinase, putative 0.1279 0.1991 1
Schistosoma mansoni serine/threonine protein kinase 0.0255 0.0198 0.0192
Echinococcus multilocularis hemicentin 1 0.0152 0.0019 0.0018
Trichomonas vaginalis AGC family protein kinase 0.0169 0.0048 0.0232
Entamoeba histolytica protein kinase, putative 0.0305 0.0286 0.1366
Echinococcus multilocularis tyrosine protein kinase Fyn 0.052 0.0662 0.0662
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0039 0.0187
Loa Loa (eye worm) TK/ACK protein kinase 0.0149 0.0012 0.0011
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0149 0.0012 0.0006
Trypanosoma cruzi cdc2-related kinase 3 0.0508 0.0642 0.3225
Trichomonas vaginalis TKL family protein kinase 0.0149 0.0012 0.0057
Echinococcus multilocularis roundabout 2 0.0179 0.0066 0.0065
Entamoeba histolytica PH domain containing protein kinase, putative 0.0748 0.1061 0.5067
Loa Loa (eye worm) hypothetical protein 0.0862 0.1262 0.1261
Leishmania major protein kinase, putative 0.0325 0.0321 0.1612
Entamoeba histolytica protein kinase, putative 0.0287 0.0254 0.1214
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.1624 0.2596 0.2596

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 0.05 uM Binding affinity to adenosine A1 receptor ChEMBL. 17689079
Ki (binding) = 0.05 uM Binding affinity to adenosine A1 receptor ChEMBL. 17689079
Ki (binding) = 8.56 uM Binding affinity to adenosine A3 receptor ChEMBL. 17689079
Ki (binding) = 8.56 uM Binding affinity to adenosine A3 receptor ChEMBL. 17689079
Ki (binding) > 10 uM Binding affinity to adenosine A2A receptor ChEMBL. 17689079
Ki (binding) > 10 uM Binding affinity to adenosine A2B receptor ChEMBL. 17689079
Ki (binding) > 10 uM Binding affinity to adenosine A2A receptor ChEMBL. 17689079
Ki (binding) > 10 uM Binding affinity to adenosine A2B receptor ChEMBL. 17689079

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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