Detailed information for compound 622546

Basic information

Technical information
  • TDR Targets ID: 622546
  • Name: [2-[(2-chloro-6-fluorophenyl)methylsulfanyl]- 4,5-dihydroimidazol-1-yl]-(4-ethoxyphenyl)met hanone
  • MW: 392.875 | Formula: C19H18ClFN2O2S
  • H donors: 0 H acceptors: 1 LogP: 4.35 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOc1ccc(cc1)C(=O)N1CCN=C1SCc1c(F)cccc1Cl
  • InChi: 1S/C19H18ClFN2O2S/c1-2-25-14-8-6-13(7-9-14)18(24)23-11-10-22-19(23)26-12-15-16(20)4-3-5-17(15)21/h3-9H,2,10-12H2,1H3
  • InChiKey: OTRAPYJVLBQVPI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • [2-[(2-chloro-6-fluoro-phenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]-(4-ethoxyphenyl)methanone
  • [2-[(2-chloro-6-fluorophenyl)methylthio]-4,5-dihydroimidazol-1-yl]-(4-ethoxyphenyl)methanone
  • [2-[(2-chloro-6-fluoro-benzyl)thio]-4,5-dihydroimidazol-1-yl]-(4-ethoxyphenyl)methanone
  • ZINC04120150

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0068 0.0122 0.0259
Schistosoma mansoni tar DNA-binding protein 0.004 0.0057 0.0107
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0087 0.0165 0.0162
Onchocerca volvulus 0.0101 0.0196 0.0406
Brugia malayi Cathepsin L-like precursor 0.0101 0.0196 0.0484
Echinococcus multilocularis cysteine protease 0.0101 0.0196 0.0193
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0101 0.0196 0.0421
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.001 0.0015
Trypanosoma cruzi cytochrome P450, putative 0.0032 0.004 0.009
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0021 0.0015 0.0087
Loa Loa (eye worm) MBCTL1 0.0031 0.0037 0.009
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0068 0.0122 0.0236
Trichomonas vaginalis PIKK family atypical protein kinase 0.0381 0.083 0.1803
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.015
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0021 0.0015 0.0087
Brugia malayi Cathepsin L-like precursor 0.0101 0.0196 0.0484
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0068 0.0122 0.1449
Echinococcus granulosus cathepsin b 0.0019 0.001 0.0007
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0135 0.0273 0.0589
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0101 0.0196 0.2352
Brugia malayi acetyltransferase, GNAT family protein 0.0091 0.0173 0.0429
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0064 0.0134
Echinococcus granulosus polycomb protein SCMH1 0.0027 0.0028 0.0026
Brugia malayi Importin beta-1 subunit 0.0018 0.0007 0.0017
Brugia malayi cytochrome P450 0.0021 0.0015 0.0035
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0015 0.0035
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0074 0.0135 0.0132
Loa Loa (eye worm) hypothetical protein 0.0016 0.0004 0.0008
Schistosoma mansoni tar DNA-binding protein 0.004 0.0057 0.0107
Echinococcus granulosus cathepsin L cysteine protease 0.0052 0.0085 0.0082
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0035
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0049 0.0078 0.0163
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0068 0.0122 0.0325
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0068 0.0122 0.1449
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0074 0.0135 1
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0049 0.0078 0.0163
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.0085 0.0876
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0033 0.0041 0.0433
Brugia malayi FAT domain containing protein 0.0154 0.0316 0.0784
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0135 0.0273 0.0589
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0068 0.0122 0.0259
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0015 0.0087
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0033 0.0041 0.028
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0024 0.0022 0.0043
Loa Loa (eye worm) hypothetical protein 0.0033 0.0043 0.0105
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0004 0.0001
Schistosoma mansoni cathepsin S (C01 family) 0.0019 0.001 0.0012
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0049 0.0078 0.0163
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.001 0.0015
Onchocerca volvulus 0.0068 0.0122 0.0244
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0135 0.0273 0.0589
Onchocerca volvulus 0.0099 0.0192 0.0397
Loa Loa (eye worm) hypothetical protein 0.0027 0.0029 0.0071
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0018 0.0009 0.0000017027
Echinococcus multilocularis cathepsin L cysteine protease 0.0101 0.0196 0.0193
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0068 0.0122 0.2168
Echinococcus granulosus cathepsin l1 0.0101 0.0196 0.0193
Brugia malayi cathepsin Z-like cysteine proteinase 0.0019 0.001 0.0023
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0029 0.0071
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0033 0.0041 0.028
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0444 0.0971 1
Trypanosoma cruzi cysteine proteinase, putative 0.0052 0.0085 0.022
Brugia malayi cathepsin L-like cysteine proteinase 0.0019 0.001 0.0023
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0033 0.0041 0.0087
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.4436 1 1
Loa Loa (eye worm) hypothetical protein 0.0124 0.0248 0.0615
Trypanosoma brucei trypanothione reductase 0.0094 0.018 0.1852
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0085 0.018
Brugia malayi cathepsin F-like cysteine proteinase 0.0033 0.0043 0.0105
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0068 0.0122 0.1163
Plasmodium falciparum serine repeat antigen 5 0.0019 0.001 0.0086
Schistosoma mansoni lamin 0.0027 0.0029 0.0051
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0094 0.018 0.1288
Echinococcus granulosus cathepsin L 0.0019 0.001 0.0007
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0101 0.0196 0.0421
Trypanosoma brucei unspecified product 0.0021 0.0015 0.015
Trypanosoma cruzi trypanothione reductase, putative 0.0094 0.018 0.0494
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0015 0.0016
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0068 0.0122 0.1163
Entamoeba histolytica cysteine protease, putative 0.0052 0.0085 0.0784
Leishmania major DNA polymerase eta, putative 0.0021 0.0015 0.0014
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.001 0.0023
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0258 0.0551 0.1096
Brugia malayi Cytochrome P450 family protein 0.0044 0.0067 0.0166
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0049 0.0078 0.0163
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0154 0.0316 0.0314
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0444 0.0971 0.2408
Leishmania major cytochrome p450-like protein 0.0021 0.0015 0.0014
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0222 0.047 0.5256
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0019 0.001 0.0129
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0021 0.0015 0.0087
Onchocerca volvulus 0.0101 0.0196 0.0406
Echinococcus multilocularis 0.0021 0.0015 0.0012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0384 0.0837 0.8615
Trichomonas vaginalis set domain proteins, putative 0.2045 0.4592 1
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0021 0.0015 0.0087
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.001 0.0015
Schistosoma mansoni cathepsin C 0.0019 0.001 0.0012
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0049 0.0078 0.0198
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0258 0.0551 0.0549
Schistosoma mansoni hypothetical protein 0.0068 0.0122 0.0236
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0444 0.0971 0.1937
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0021 0.0015 0.0087
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0015 0.0035
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0068 0.0122 0.0259
Onchocerca volvulus 0.0068 0.0122 0.0244
Schistosoma mansoni cytochrome P450 0.0021 0.0015 0.0022
Echinococcus multilocularis 0.0068 0.0122 0.0119
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0101 0.0196 0.0421
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0023
Echinococcus granulosus serine protein kinase ATM 0.02 0.0419 0.0416
Entamoeba histolytica cysteine protease, putative 0.0101 0.0196 0.1935
Leishmania major hypothetical protein, conserved 0.0124 0.0248 0.0661
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.02 0.0419 0.1038
Brugia malayi cathepsin L-like precursor 0.0068 0.012 0.0297
Giardia lamblia Protein LRP16 0.0042 0.0062 0.0545
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0019 0.001 0.0012
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0068 0.0122 0.0325
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0214 0.0452 0.3264
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0021 0.0015 0.0087
Echinococcus multilocularis tumor protein p63 0.0677 0.1499 0.1496
Trypanosoma brucei Macro domain containing protein, putative 0.0042 0.0062 0.0639
Echinococcus granulosus neuropeptide s receptor 0.0294 0.0631 0.0629
Echinococcus multilocularis lamin 0.0027 0.0029 0.0026
Loa Loa (eye worm) phosphatidylinositol 3 0.0068 0.0122 0.03
Entamoeba histolytica hypothetical protein 0.0068 0.0122 0.1163
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0033 0.0042 0.0087
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0021 0.0016 0.0029
Loa Loa (eye worm) hypothetical protein 0.0222 0.047 0.1166
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0024 0.0022 0.0039
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0019 0.001 0.0012
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0074 0.0135 0.096
Brugia malayi hypothetical protein 0.008 0.0149 0.0368
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0068 0.0122 0.2168
Onchocerca volvulus Cathepsin L homolog 0.0101 0.0196 0.0406
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0024 0.0022 0.0359
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1797 0.4031 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0052 0.0085 0.0163
Echinococcus granulosus histone acetyltransferase MYST2 0.0031 0.0037 0.0034
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0033 0.0041 0.0424
Schistosoma mansoni sex comb on midleg homolog 0.0027 0.0028 0.0049
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0049 0.0078 0.0163
Loa Loa (eye worm) hypothetical protein 0.0031 0.0037 0.009
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0051 0.0595
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0074 0.0135 0.2409
Loa Loa (eye worm) hypothetical protein 0.0131 0.0265 0.0656
Loa Loa (eye worm) RNA binding protein 0.004 0.0057 0.0141
Plasmodium falciparum serine repeat antigen 4 0.0019 0.001 0.0086
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0101 0.0196 0.0421
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0101 0.0196 0.0421
Echinococcus granulosus cpg binding protein 0.0021 0.0014 0.0012
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0135 0.0273 0.0589
Trypanosoma brucei trans-sialidase, putative 0.0018 0.0009 0.0092
Echinococcus granulosus cytochrome P450 2K1 0.0021 0.0015 0.0012
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0068 0.0122 0.0119
Trichomonas vaginalis PIKK family atypical protein kinase 0.0444 0.0971 0.211
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0033 0.0041 0.047
Entamoeba histolytica cysteine protease, putative 0.0052 0.0085 0.0784
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0068 0.0122 0.0259
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0068 0.0122 0.0259
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0068 0.0122 0.0259
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0027 0.0028 0.0056
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0101 0.0196 0.0421
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0019 0.001 0.0129
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0021 0.0015 0.0087
Echinococcus multilocularis polycomb protein SCMH1 0.0027 0.0028 0.0026
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0021 0.0016 0.0029
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0024 0.0022 0.0229
Trichomonas vaginalis PIKK family atypical protein kinase 0.0381 0.083 0.1803
Loa Loa (eye worm) phosphatidylinositol 3 0.0068 0.0122 0.03
Entamoeba histolytica acetyltransferase, GNAT family 0.0025 0.0023 0.0139
Entamoeba histolytica hypothetical protein 0.0033 0.0041 0.0329
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0049 0.0078 0.0198
Trichomonas vaginalis PIKK family atypical protein kinase 0.0416 0.0908 0.1974
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0033 0.0043 0.0105
Trichomonas vaginalis PIKK family atypical protein kinase 0.0096 0.0184 0.0395
Loa Loa (eye worm) glutaminase 2 0.0154 0.0316 0.0783
Trypanosoma cruzi major cysteine proteinase, putative 0.0019 0.001 0.0002
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0354 0.0768 0.7906
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0015 0.0087
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0021 0.0015 0.0087
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0384 0.0837 0.8615
Schistosoma mansoni hypothetical protein 0.037 0.0804 0.1603
Echinococcus granulosus peptidase Clp S14 family 0.0048 0.0077 0.0074
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0019 0.001 0.0129
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0068 0.0122 0.1251
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0048 0.0077 0.0542
Echinococcus multilocularis microtubule associated protein 2 0.2224 0.4997 0.4996
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0049 0.0078 0.0798
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0384 0.0837 0.8615
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0068 0.0122 0.0236
Trypanosoma cruzi trans-sialidase, putative 0.0018 0.0009 0.0000017027
Echinococcus multilocularis thioredoxin glutathione reductase 0.0094 0.018 0.0177
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0068 0.0122 0.0325
Entamoeba histolytica cysteine protease, putative 0.0052 0.0085 0.0784
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0033 0.0041 0.0075
Mycobacterium tuberculosis Conserved hypothetical protein 0.0108 0.0213 0.1525
Trichomonas vaginalis PIKK family atypical protein kinase 0.0255 0.0544 0.1179
Loa Loa (eye worm) cysteine protease 0.0101 0.0196 0.0484
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0033 0.0041 0.0703
Echinococcus granulosus cathepsin L cysteine proteinase 0.0101 0.0196 0.0193
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0068 0.0122 0.031
Schistosoma mansoni aldehyde dehydrogenase 0.0075 0.0138 0.0268
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0024 0.0022 0.0221
Echinococcus multilocularis cathepsin b 0.0019 0.001 0.0007
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0258 0.0551 0.1096
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0154 0.0316 0.0314
Trichomonas vaginalis PIKK family atypical protein kinase 0.0416 0.0908 0.1974
Toxoplasma gondii histone lysine methyltransferase SET1 0.0049 0.0078 0.0845
Entamoeba histolytica cysteine protease, putative 0.0052 0.0085 0.0784
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0019 0.001 0.0023
Brugia malayi intermediate filament protein 0.0027 0.0029 0.0071
Plasmodium falciparum ataxin-2 like protein, putative 0.0124 0.0248 0.2994
Brugia malayi Thioredoxin reductase 0.0094 0.018 0.0445
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0075 0.0138 0.098
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0021 0.0015 0.0087
Plasmodium vivax serine-repeat antigen (SERA) 0.0019 0.001 0.0129
Schistosoma mansoni hypothetical protein 0.0279 0.0597 0.1189
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0354 0.0768 0.2193
Giardia lamblia NADH oxidase lateral transfer candidate 0.0033 0.0041 0.0327
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0101 0.0196 0.0421
Echinococcus granulosus cathepsin l1 0.0068 0.012 0.0118
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0019 0.001 0.0129
Schistosoma mansoni fkbp-rapamycin associated protein 0.02 0.0419 0.0831
Leishmania major hypothetical protein, unknown function 0.0068 0.0122 0.031
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0021 0.0015 0.0087
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0024 0.0022 0.0035
Brugia malayi cathepsin B-like cysteine proteinase 0.0019 0.001 0.0023
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0019 0.001 0.0129
Giardia lamblia GTOR 0.0444 0.0971 1
Echinococcus multilocularis neuropeptide s receptor 0.0294 0.0631 0.0629
Brugia malayi Cytochrome P450 family protein 0.0032 0.004 0.0098
Trypanosoma cruzi trypanothione reductase, putative 0.0033 0.0041 0.0093
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0021 0.0015 0.0087
Schistosoma mansoni hypothetical protein 0.016 0.033 0.0653
Trypanosoma brucei cytochrome P450, putative 0.0032 0.004 0.0413
Trypanosoma brucei trans-sialidase 0.0018 0.0009 0.0092
Trichomonas vaginalis PIKK family atypical protein kinase 0.02 0.0419 0.0907
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0021 0.0015 0.0016
Schistosoma mansoni tar DNA-binding protein 0.004 0.0057 0.0107
Brugia malayi Cathepsin L-like precursor 0.0101 0.0196 0.0484
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0033 0.0043 0.0105
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0074 0.0135 0.4425
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0052 0.0085 0.0163
Entamoeba histolytica cysteine protease, putative 0.0052 0.0085 0.0784
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0097 0.0188 0.0516
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0068 0.0122 0.1251
Trichomonas vaginalis PIKK family atypical protein kinase 0.0381 0.083 0.1803
Brugia malayi Cytochrome P450 family protein 0.0032 0.004 0.0098
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.001 0.0023
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0068 0.0122 0.0325
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0041 0.0093
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0169 0.033
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0101 0.0196 0.0421
Leishmania major cathepsin L-like protease 0.0101 0.0196 0.0515
Entamoeba histolytica hypothetical protein 0.0068 0.0122 0.1163
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0049 0.0078 0.0163
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0004 0.0008
Loa Loa (eye worm) hypothetical protein 0.0051 0.0082 0.0203
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0049 0.0078 0.0798
Toxoplasma gondii cathepsin B 0.0019 0.001 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0064 0.0134
Echinococcus granulosus MACRO domain containing protein 2 0.0042 0.0062 0.0059
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0089 0.0169 0.0166
Trypanosoma brucei DNA polymerase eta, putative 0.0021 0.0015 0.015
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0021 0.0016 0.0013
Echinococcus granulosus histone lysine methyltransferase setb 0.0258 0.0551 0.0549
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0019 0.001 0.0015
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0444 0.0971 0.0969
Brugia malayi hypothetical protein 0.0033 0.0041 0.0101
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0029 0.0033 0.0339
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0068 0.0122 0.1163
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0005
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0032 0.004 0.0273
Toxoplasma gondii aldehyde dehydrogenase 0.0075 0.0138 0.1516
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0018 0.0009 0.0000017027
Leishmania major cathepsin L-like protease 0.0101 0.0196 0.0515
Schistosoma mansoni hypothetical protein 0.037 0.0804 0.1603
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0101 0.0196 0.2352
Trypanosoma brucei trans-sialidase, putative 0.0018 0.0009 0.0092
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0416 0.0909 0.9358
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0021 0.0016 0.0024
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0019 0.001 0.0129
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.001 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0019 0.001 0.0015
Schistosoma mansoni ap endonuclease 0.0037 0.0051 0.0095
Echinococcus multilocularis peptidase Clp (S14 family) 0.0048 0.0077 0.0074
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0068 0.0122 0.0259
Entamoeba histolytica hypothetical protein 0.0033 0.0041 0.0329
Plasmodium vivax unspecified product 0.0019 0.001 0.0129
Trichomonas vaginalis PIKK family atypical protein kinase 0.0354 0.0768 0.1667
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.0085 0.0876
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0027 0.0028 0.0041
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0049 0.0078 0.0075
Echinococcus multilocularis cathepsin L cysteine protease 0.0101 0.0196 0.0193
Brugia malayi Cathepsin L-like precursor 0.0101 0.0196 0.0484
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0068 0.0122 0.1336
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0021 0.0015 0.0087
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0068 0.0122 0.03
Trichomonas vaginalis glutathione reductase, putative 0.0033 0.0041 0.0084
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0123 0.0246 0.2538
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0004 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0101 0.0196 0.0421
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0101 0.0196 0.0421
Plasmodium falciparum ataxin-2 like protein, putative 0.0124 0.0248 0.2994
Echinococcus multilocularis serine protein kinase ATM 0.02 0.0419 0.0416
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0122 0.0259
Echinococcus granulosus MACRO domain containing protein 2 0.0042 0.0062 0.0059
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0068 0.0122 0.0325
Loa Loa (eye worm) hypothetical protein 0.0068 0.0122 0.03
Brugia malayi Papain family cysteine protease containing protein 0.0052 0.0085 0.021
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0206 0.0433 0.1224
Brugia malayi RNA, U transporter 1 0.005 0.0081 0.0199
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0021 0.0015 0.0087
Trypanosoma cruzi PAB1-binding protein , putative 0.0124 0.0248 0.0692
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0101 0.0196 0.0421
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0444 0.0971 0.0969
Brugia malayi mbt repeat family protein 0.0027 0.0028 0.0069
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0384 0.0837 0.8615
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.02 0.0419 0.1184
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.001 0.0015
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0444 0.0971 1
Treponema pallidum exodeoxyribonuclease (exoA) 0.0037 0.0051 0.1061
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0052 0.0085 0.022
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0238 0.0506 0.3657
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0068 0.0122 0.0259
Loa Loa (eye worm) TAR-binding protein 0.004 0.0057 0.0141
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0384 0.0837 0.8615
Mycobacterium tuberculosis Possible lipoprotein LppD 0.0042 0.0062 0.0432
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0113 0.0224 0.0221
Plasmodium falciparum thioredoxin reductase 0.0033 0.0041 0.047
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0031 0.0037 0.0034
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0444 0.0971 0.278
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0023
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.02 0.0419 0.1184
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0135 0.0273 0.0589
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0049 0.0078 0.0163
Schistosoma mansoni cathepsin s 0.0033 0.0043 0.0078
Trypanosoma cruzi cysteine peptidase, putative 0.0101 0.0196 0.054
Leishmania major mitochondrial DNA polymerase beta 0.0206 0.0433 0.117
Trypanosoma brucei PAB1-binding protein , putative 0.0124 0.0248 0.2557
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0078 0.0163
Plasmodium falciparum serine repeat antigen 7 0.0019 0.001 0.0086
Leishmania major phosphatidylinositol 3-kinase, putative 0.0354 0.0768 0.2098
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0131 0.0265 0.074
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0354 0.0768 0.7906
Loa Loa (eye worm) mbt repeat family protein 0.0027 0.0028 0.0069
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0206 0.0433 0.4455
Trichomonas vaginalis PIKK family atypical protein kinase 0.02 0.0419 0.0907
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0021 0.0015 0.0087
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0049 0.0078 0.0163
Echinococcus multilocularis SAM and MBT domain containing protein 0.0027 0.0028 0.0026
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0018 0.0009 0.0000017027
Trypanosoma brucei trans-sialidase, putative 0.0018 0.0009 0.0092
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0101 0.0196 0.0421
Trichomonas vaginalis PIKK family atypical protein kinase 0.0409 0.0893 0.1939
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0024 0.0022 0.002
Entamoeba histolytica hypothetical protein 0.0068 0.0122 0.1163
Leishmania major phosphatidylinositol kinase related protein, putative 0.0068 0.0122 0.031
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0015 0.0087
Trypanosoma cruzi Macro domain containing protein, putative 0.0042 0.0062 0.0153
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0074 0.0135 0.096
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0015 0.015
Echinococcus granulosus microtubule associated protein 2 0.2224 0.4997 0.4996
Plasmodium falciparum serine repeat antigen 1 0.0019 0.001 0.0086
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0101 0.0196 0.0421
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0384 0.0837 0.8615
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0004 0.0008
Trypanosoma cruzi target of rapamycin kinase 3 0.0416 0.0909 0.26
Loa Loa (eye worm) phosphatidylinositol 3 0.0068 0.0122 0.03
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0089 0.0169 0.0417
Trypanosoma brucei RNA helicase, putative 0.016 0.033 0.3397
Loa Loa (eye worm) hypothetical protein 0.0068 0.0122 0.03
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0004 0.0001
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0089 0.0169 0.0166
Plasmodium falciparum glutathione reductase 0.0033 0.0041 0.047
Schistosoma mansoni cathepsin F (C01 family) 0.0068 0.012 0.0233
Schistosoma mansoni tar DNA-binding protein 0.004 0.0057 0.0107
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0101 0.0196 0.0484
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.02 0.0419 0.0831
Onchocerca volvulus 0.0101 0.0196 0.0406
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0068 0.0122 0.03
Leishmania major cathepsin L-like protease 0.0384 0.0837 0.2288
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0021 0.0015 0.0087
Trypanosoma brucei trans-sialidase, putative 0.0018 0.0009 0.0092
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0015 0.0026
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0101 0.0196 0.0193
Echinococcus granulosus neuropeptide receptor A26 0.0294 0.0631 0.0629
Echinococcus granulosus dna polymerase kappa 0.0021 0.0015 0.0012
Echinococcus multilocularis cpg binding protein 0.0021 0.0014 0.0012
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.004 0.0098
Echinococcus multilocularis geminin 0.037 0.0804 0.0802
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0068 0.0122 0.1163
Trypanosoma cruzi cysteine peptidase, putative 0.0384 0.0837 0.2392
Trypanosoma cruzi trans-sialidase, putative 0.0018 0.0009 0.0000017027
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0015 0.0016
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0049 0.0078 0.0163
Entamoeba histolytica hypothetical protein, conserved 0.0042 0.0062 0.0545
Onchocerca volvulus 0.0101 0.0196 0.0406
Loa Loa (eye worm) hypothetical protein 0.0068 0.012 0.0297
Echinococcus granulosus dnaJ subfamily B 0.0279 0.0597 0.0595
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.0232 0.0576
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0019 0.001 0.0015
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0068 0.0122 0.0119
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0019 0.001 0.0015
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0024 0.0022 0.0054
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0068 0.0122 0.03
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0021 0.0015 0.0087
Entamoeba histolytica cysteine proteinase, putative 0.0068 0.012 0.115
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0049 0.0078 0.0163
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.015
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0051 0.089
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0444 0.0971 0.266
Schistosoma mansoni peptidase Clp (S14 family) 0.0074 0.0135 0.0262
Brugia malayi Cathepsin L-like precursor 0.0068 0.012 0.0297
Onchocerca volvulus Cathepsin L homolog 0.0101 0.0196 0.0406
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0075 0.0138 0.0135
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.025 0.0533 0.5489
Echinococcus granulosus dna polymerase eta 0.0021 0.0015 0.0012
Trichomonas vaginalis glutaminase, putative 0.0154 0.0316 0.0683
Echinococcus multilocularis muscleblind protein 1 0.0094 0.018 0.0177
Leishmania major hypothetical protein, conserved 0.1617 0.3623 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0015 0.0016
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0041 0.0093
Echinococcus multilocularis cathepsin L 0.0019 0.001 0.0007
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0068 0.0122 0.1163
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0021 0.0015 0.0087
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0074 0.0135 0.1484
Trichomonas vaginalis conserved hypothetical protein 0.0154 0.0316 0.0684
Loa Loa (eye worm) phosphatidylinositol 3 0.0068 0.0122 0.03
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0019 0.001 0.0015
Brugia malayi cathepsin L precursor 0.0019 0.001 0.0023
Loa Loa (eye worm) hypothetical protein 0.0094 0.018 0.0444
Brugia malayi glutaminase DH11.1 0.0154 0.0316 0.0783
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0624 0.1379 1
Entamoeba histolytica cysteine proteinase, putative 0.0052 0.0085 0.0784
Loa Loa (eye worm) thioredoxin reductase 0.0094 0.018 0.0445
Trypanosoma cruzi cytochrome P450, putative 0.0032 0.004 0.009
Trypanosoma cruzi cysteine peptidase, putative 0.0052 0.0085 0.022
Schistosoma mansoni hypothetical protein 0.0188 0.0392 0.0778
Toxoplasma gondii HEAT repeat-containing protein 0.0018 0.0007 0.0053
Brugia malayi Cathepsin L-like precursor 0.0068 0.012 0.0297
Loa Loa (eye worm) phosphatidylinositol 3 0.0354 0.0768 0.1904
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0021 0.0015 0.0087
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0041 0.0093
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0041 0.0093
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0023
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0046 0.0113
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0025 0.0025 0.0411
Trypanosoma cruzi trans-sialidase, putative 0.0018 0.0009 0.0000017027
Plasmodium vivax vivapain-2 0.0101 0.0196 0.3519
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0019 0.001 0.0086
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0068 0.0122 0.0119
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0015 0.0026
Echinococcus granulosus geminin 0.037 0.0804 0.0802
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0101 0.0196 0.0421
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0033 0.0042 0.0087
Onchocerca volvulus 0.0027 0.0029 0.0042
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0101 0.0196 0.0421
Trypanosoma brucei trans-sialidase, putative 0.0018 0.0009 0.0092
Plasmodium falciparum serine repeat antigen 3 0.0019 0.001 0.0086
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0258 0.0551 0.6163
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0033 0.0041 0.0424
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0097 0.0188 0.0493
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0015 0.0012
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.004 0.0098
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0068 0.0122 0.03
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0021 0.0016 0.0039
Schistosoma mansoni hypothetical protein 0.0021 0.0015 0.0022
Echinococcus multilocularis neuropeptide receptor A26 0.0294 0.0631 0.0629
Brugia malayi MH2 domain containing protein 0.0117 0.0232 0.0576
Trichomonas vaginalis PIKK family atypical protein kinase 0.0409 0.0893 0.1939
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.001 0.0023
Trypanosoma cruzi PAB1-binding protein , putative 0.0124 0.0248 0.0692
Mycobacterium tuberculosis Probable oxidoreductase 0.0238 0.0506 0.3657
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0041 0.0093
Schistosoma mansoni hypothetical protein 0.0056 0.0093 0.0179
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0015 0.0087
Mycobacterium ulcerans aldehyde dehydrogenase 0.0075 0.0138 0.098
Treponema pallidum NADH oxidase 0.0033 0.0041 0.0646
Echinococcus multilocularis MACRO domain containing protein 2 0.0042 0.0062 0.0059
Loa Loa (eye worm) hypothetical protein 0.0028 0.003 0.0073
Plasmodium vivax hypothetical protein, conserved 0.0068 0.0122 0.2168
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0049 0.0078 0.0163
Echinococcus granulosus histone acetyltransferase KAT2B 0.0027 0.0028 0.0025
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0019 0.001 0.0012
Schistosoma mansoni ap endonuclease 0.0037 0.0051 0.0095
Toxoplasma gondii exonuclease III APE 0.0037 0.0051 0.0549
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0068 0.0122 0.2168
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0384 0.0837 0.8615
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0068 0.0122 0.03
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0015 0.0035
Toxoplasma gondii preprocathepsin c precursor, putative 0.0019 0.001 0.0079
Schistosoma mansoni tar DNA-binding protein 0.004 0.0057 0.0107
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0024 0.0022 0.0131
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0074 0.0135 1
Trypanosoma cruzi cysteine protease, putative 0.0052 0.0085 0.022
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0068 0.0122 0.0259
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0019 0.001 0.0023
Onchocerca volvulus Cathepsin F homolog 0.0101 0.0196 0.0406
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.0232 0.0576
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0351 0.0761 0.2174
Schistosoma mansoni DNA polymerase eta 0.0021 0.0015 0.0021
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0089 0.0169 0.0166
Brugia malayi cathepsin Z-like cysteine proteinase 0.0019 0.001 0.0023
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0068 0.0122 0.0236
Trichomonas vaginalis PIKK family atypical protein kinase 0.0416 0.0908 0.1974
Echinococcus multilocularis cathepsin L 0.0052 0.0085 0.0082
Schistosoma mansoni cpg binding protein 0.002 0.0012 0.0016
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0015 0.0021
Schistosoma mansoni hypothetical protein 0.0042 0.0062 0.0116
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0068 0.0122 0.0119
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0062 0.1084
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0049 0.0078 0.0163
Onchocerca volvulus 0.0027 0.0029 0.0042
Trypanosoma brucei importin beta-1 subunit, putative 0.0018 0.0007 0.0076
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0068 0.0122 0.0119
Trichomonas vaginalis ganglioside induced differentiation associated protein, putative 0.0042 0.0062 0.013
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0024 0.0022 0.0052
Loa Loa (eye worm) hypothetical protein 0.02 0.0419 0.1038
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0037 0.0051 0.0434
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0037 0.0051 0.0123
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0021 0.0015 0.0087
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0021 0.0015 0.0087
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0021 0.0015 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0409 0.0893 0.1939
Brugia malayi Muscleblind-like protein 0.0094 0.018 0.0444
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0033 0.0041 0.028
Toxoplasma gondii hypothetical protein 0.0025 0.0025 0.0254
Trichomonas vaginalis PIKK family atypical protein kinase 0.0409 0.0893 0.1939
Echinococcus granulosus importin subunit beta 1 0.0018 0.0007 0.0005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0384 0.0837 0.8615
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0019 0.001 0.0015
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0354 0.0768 0.2098
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0049 0.0078 0.0163
Trichomonas vaginalis PIKK family atypical protein kinase 0.0285 0.0611 0.1326
Trichomonas vaginalis PIKK family atypical protein kinase 0.0444 0.0971 0.211
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0027 0.0028 0.0286
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0068 0.0122 0.0325
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0068 0.0122 0.0259
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0068 0.0122 0.0119
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0021 0.0015 0.0087
Trypanosoma cruzi cruzipain precursor, putative 0.0033 0.0043 0.0098
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0068 0.0122 0.0325
Trichomonas vaginalis PIKK family atypical protein kinase 0.0354 0.0768 0.1667
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0056 0.0093 0.0091
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0021 0.0016 0.0039
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0068 0.012 0.0256
Trichomonas vaginalis conserved hypothetical protein 0.0131 0.0265 0.0572
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0021 0.0015 0.0087
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0015 0.0012
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0021 0.0015 0.0087
Brugia malayi Cathepsin L-like precursor 0.0101 0.0196 0.0484
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0029 0.0033 0.0069
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0018 0.0009 0.0000017027
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0075 0.0138 0.0135
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0027 0.0028 0.0464
Loa Loa (eye worm) hypothetical protein 0.0035 0.0046 0.0113
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0068 0.0122 0.1251
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0033 0.0041 0.0093
Echinococcus granulosus tumor protein p63 0.0677 0.1499 0.1496
Schistosoma mansoni cathepsin F (C01 family) 0.0101 0.0196 0.0384
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0037 0.0051 0.0049
Plasmodium vivax SET domain protein, putative 0.0258 0.0551 1
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0068 0.0122 0.1163
Echinococcus multilocularis dnaJ subfamily B 0.0279 0.0597 0.0595
Entamoeba histolytica cysteine protease, putative 0.0052 0.0085 0.0784
Schistosoma mansoni aldehyde dehydrogenase 0.0075 0.0138 0.0268
Loa Loa (eye worm) phosphatidylinositol 3 0.0444 0.0971 0.2408
Entamoeba histolytica cysteine proteinase 1, putative 0.0052 0.0085 0.0784
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0051 0.0083 0.0158
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0021 0.0016 0.0029
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0019 0.001 0.0086
Leishmania major cytochrome p450-like protein 0.0021 0.0015 0.0014
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0101 0.0196 0.0421
Echinococcus multilocularis cathepsin b 0.0019 0.001 0.0007
Trypanosoma cruzi Macro domain containing protein, putative 0.0042 0.0062 0.0153
Echinococcus multilocularis lamin dm0 0.0027 0.0029 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.02 0.0419 0.0907
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.0082 0.0203
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0068 0.0122 0.0119
Loa Loa (eye worm) hypothetical protein 0.0074 0.0135 0.0333
Toxoplasma gondii macro domain-containing protein 0.0042 0.0062 0.0668
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.015
Brugia malayi Cathepsin L-like precursor 0.0033 0.0043 0.0105
Trichomonas vaginalis PIKK family atypical protein kinase 0.0416 0.0908 0.1974
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0019 0.001 0.0012
Echinococcus granulosus cathepsin l cysteine peptidase 0.0101 0.0196 0.0193
Leishmania major phosphatidylinositol 4-kinase, putative 0.0068 0.0122 0.031
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0033 0.0041 0.0087
Loa Loa (eye worm) hypothetical protein 0.0258 0.0551 0.1366
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0037 0.0051 0.0049
Echinococcus granulosus nuclear factor of activated T cells 5 0.0087 0.0165 0.0162
Mycobacterium ulcerans hypothetical protein 0.0108 0.0213 0.1525
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0019 0.001 0.0012
Trypanosoma cruzi DNA polymerase eta, putative 0.0021 0.0015 0.0016
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0049 0.0078 0.0163
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0019 0.001 0.0015
Brugia malayi F/Y-rich N-terminus family protein 0.0015 0.0003 0.0005
Loa Loa (eye worm) glutaminase 0.0154 0.0316 0.0783
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0023
Plasmodium vivax importin-beta 2, putative 0.0018 0.0007 0.0087
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.0082 0.0203
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0068 0.0122 0.1163
Plasmodium falciparum serine repeat antigen 8 0.0019 0.001 0.0086
Schistosoma mansoni hypothetical protein 0.0154 0.0316 0.0626
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0019 0.001 0.0086
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0024 0.0022 0.0054
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0101 0.0196 0.0421
Entamoeba histolytica cysteine proteinase 2 0.0052 0.0085 0.0784
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0206 0.0433 0.1224
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.015
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0033 0.0041 0.0093
Brugia malayi TAR-binding protein 0.004 0.0057 0.0141
Plasmodium falciparum serine repeat antigen 6 0.0019 0.001 0.0086
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0074 0.0135 0.0132
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0021 0.0015 0.0087
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0029 0.0071
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0051 0.0106
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0068 0.0122 0.0236
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0019 0.001 0.0012
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0068 0.0122 0.2168
Trichomonas vaginalis ganglioside induced differentiation associated protein, putative 0.0042 0.0062 0.013
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0021 0.0015 0.0087
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0033 0.0041 0.0038
Brugia malayi Pre-SET motif family protein 0.1797 0.4031 1
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0068 0.0122 0.0259
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0248 0.0529 0.0526
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0089 0.0169 0.0417
Echinococcus multilocularis Zinc finger, PHD finger 0.0068 0.0122 0.0119
Brugia malayi mbt repeat family protein 0.0027 0.0028 0.0069
Echinococcus multilocularis MACRO domain containing protein 2 0.0042 0.0062 0.0059
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0068 0.012 0.0256
Plasmodium falciparum thioredoxin reductase 0.0094 0.018 0.216
Entamoeba histolytica hypothetical protein, conserved 0.0042 0.0062 0.0545
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0049 0.0078 0.0163
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0113 0.0224 0.0221
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0019 0.001 0.0023
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0037 0.0051 0.0434
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0021 0.0015 0.0087
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0033 0.0041 0.0039
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0068 0.0122 0.0236
Onchocerca volvulus 0.0068 0.012 0.0241
Echinococcus granulosus histone acetyltransferase KAT2B 0.0088 0.0168 0.0165
Leishmania major cathepsin L-like protease 0.0384 0.0837 0.2288
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0021 0.0015 0.0087
Giardia lamblia DINP protein human, muc B family 0.0021 0.0015 0.0051
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0041 0.0093
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0101 0.0196 0.0421
Plasmodium falciparum importin beta, putative 0.0018 0.0007 0.0058
Trichomonas vaginalis PIKK family atypical protein kinase 0.0388 0.0846 0.1838
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0049 0.0078 0.0147
Echinococcus multilocularis snurportin 1 0.0188 0.0392 0.039
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0068 0.0122 0.0259
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0068 0.0122 0.1336
Toxoplasma gondii thioredoxin reductase 0.0094 0.018 0.1992
Entamoeba histolytica hypothetical protein 0.0068 0.0122 0.1163
Plasmodium falciparum serine repeat antigen 2 0.0019 0.001 0.0086
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0068
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0056 0.0093 0.0091
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.004 0.0057 0.0141
Plasmodium falciparum cysteine proteinase falcipain 3 0.0101 0.0196 0.2352
Loa Loa (eye worm) acetyltransferase 0.0091 0.0173 0.0429
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0018 0.0009 0.0000017027
Leishmania major cysteine peptidase A (CPA) 0.0101 0.0196 0.0515
Echinococcus multilocularis musashi 0.0027 0.0029 0.0026
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0068 0.0122 0.03
Loa Loa (eye worm) hypothetical protein 0.0099 0.0192 0.0474
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0049 0.0078 0.0163
Schistosoma mansoni transcription factor LCR-F1 0.0033 0.0041 0.0075
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0037 0.0051 0.0116
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0021 0.0015 0.0087
Brugia malayi cathepsin F-like cysteine proteinase 0.0019 0.001 0.0023
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0052 0.0085 0.0163
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0624 0.1379 1
Brugia malayi Cytochrome P450 family protein 0.0021 0.0015 0.0035
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0024 0.0022 0.024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0068 0.0122 0.0259
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0101 0.0196 0.0421
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0068 0.0122 0.0325
Entamoeba histolytica cysteine proteinase, putative 0.0052 0.0085 0.0784
Echinococcus multilocularis dna polymerase eta 0.0021 0.0015 0.0012
Echinococcus granulosus thioredoxin glutathione reductase 0.0094 0.018 0.0177
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0033 0.0041 0.0039
Leishmania major cathepsin L-like protease 0.0101 0.0196 0.0515
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0068 0.0122 0.1449
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0074 0.0135 0.161
Brugia malayi fibroinase precursor 0.0019 0.001 0.0023
Plasmodium falciparum cysteine proteinase falcipain 1 0.0052 0.0085 0.1005
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0068 0.0122 0.1336
Onchocerca volvulus 0.002 0.0012 0.0005
Echinococcus multilocularis muscleblind protein 0.0094 0.018 0.0177
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.001 0.0015
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0019 0.001 0.0129
Trypanosoma brucei importin beta-1 subunit, putative 0.0018 0.0007 0.0076
Loa Loa (eye worm) phosphatidylinositol 3 0.0068 0.0122 0.03
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0023
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0037 0.0051 0.0355
Entamoeba histolytica cysteine proteinase, putative 0.0052 0.0085 0.0784
Trypanosoma cruzi major cysteine proteinase, putative 0.0302 0.0651 0.1854
Mycobacterium ulcerans aldehyde dehydrogenase 0.0075 0.0138 0.098
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0033 0.0041 0.0703
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0214 0.0452 0.3264
Trichomonas vaginalis PIKK family atypical protein kinase 0.0388 0.0846 0.1838
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0019 0.001 0.0012
Leishmania major DNA polymerase kappa, putative 0.0021 0.0015 0.0014
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0049 0.0078 0.0163
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0021 0.0015 0.0087
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0169 0.033
Toxoplasma gondii cathepsin CPC1 0.0019 0.001 0.0079
Trichomonas vaginalis PIKK family atypical protein kinase 0.0409 0.0893 0.1939
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0025 0.0025 0.0164
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0068 0.0122 0.0325
Toxoplasma gondii cytochrome p450 superfamily protein 0.0021 0.0015 0.0135
Onchocerca volvulus 0.0101 0.0196 0.0406
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0015 0.0021
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0021 0.0015 0.0087
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.001 0.0015
Brugia malayi CXXC zinc finger family protein 0.002 0.0012 0.0028
Trichomonas vaginalis bromodomain-containing protein, putative 0.0027 0.0028 0.0056
Toxoplasma gondii cathepsin CPL 0.0101 0.0196 0.2169
Trypanosoma cruzi cysteine proteinase, putative 0.0052 0.0085 0.022
Schistosoma mansoni hypothetical protein 0.0035 0.0046 0.0084
Trichomonas vaginalis PIKK family atypical protein kinase 0.0381 0.083 0.1804
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.02 0.0419 0.0416
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0021 0.0015 0.0016
Loa Loa (eye worm) hypothetical protein 0.0021 0.0016 0.0039
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0019 0.001 0.0002
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0068 0.0122 0.0119
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0101 0.0196 0.0421
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0354 0.0768 0.0765
Trichomonas vaginalis PIKK family atypical protein kinase 0.0416 0.0908 0.1974
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0068 0.0122 0.0325
Onchocerca volvulus 0.0027 0.0028 0.0041
Brugia malayi Papain family cysteine protease containing protein 0.0101 0.0196 0.0484
Brugia malayi Cathepsin L-like precursor 0.0101 0.0196 0.0484
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0049 0.0078 0.0163
Trichomonas vaginalis conserved hypothetical protein 0.0222 0.047 0.1019
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0624 0.1379 1
Entamoeba histolytica cysteine proteinase, putative 0.0101 0.0196 0.1935
Loa Loa (eye worm) cytochrome P450 0.0021 0.0015 0.0035
Schistosoma mansoni hypothetical protein 0.0033 0.0041 0.0075
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0015 0.015
Echinococcus multilocularis importin subunit beta 1 0.0018 0.0007 0.0005
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0015 0.0012
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0068 0.0122 0.0259
Mycobacterium ulcerans glutaminase 0.0154 0.0316 0.2276
Plasmodium vivax ataxin-2 like protein, putative 0.0124 0.0248 0.448
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0444 0.0971 0.278
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.015
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0019 0.001 0.0012
Toxoplasma gondii target of rapamycin (TOR), putative 0.0409 0.0893 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0381 0.083 0.1804
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0091 0.0173 0.0339
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0033 0.0041 0.0087
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0258 0.0551 0.1096
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0027 0.0028 0.0049
Entamoeba histolytica cysteine protease, putative 0.0052 0.0085 0.0784
Schistosoma mansoni cathepsin B (C01 family) 0.0019 0.001 0.0012
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.02 0.0419 0.4313
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0444 0.0971 1
Plasmodium vivax hypothetical protein 0.0068 0.0122 0.2168
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0214 0.0452 0.3264
Mycobacterium leprae conserved hypothetical protein 0.0068 0.0122 0.0864
Onchocerca volvulus 0.0101 0.0196 0.0406
Onchocerca volvulus 0.0101 0.0196 0.0406
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0258 0.0551 0.1096
Schistosoma mansoni hypothetical protein 0.0042 0.0062 0.0116
Trichomonas vaginalis PIKK family atypical protein kinase 0.0381 0.083 0.1804
Trichomonas vaginalis PIKK family atypical protein kinase 0.0289 0.0622 0.135
Plasmodium vivax unspecified product 0.0052 0.0085 0.1503
Loa Loa (eye worm) hypothetical protein 0.0068 0.012 0.0297
Echinococcus multilocularis cysteine protease 0.0101 0.0196 0.0193
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0024 0.0022 0.0052
Loa Loa (eye worm) hypothetical protein 0.0068 0.012 0.0297
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0049 0.0078 0.0198
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0033 0.0041 0.0424
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0031 0.0037 0.009
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0188 0.0392 0.0972
Leishmania major cytochrome p450-like protein 0.0032 0.004 0.0084
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0037 0.0051 0.053
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0101 0.0196 0.0421
Brugia malayi glutathione reductase 0.0094 0.018 0.0445
Echinococcus multilocularis tar DNA binding protein 0.004 0.0057 0.0055
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0049 0.0078 0.0163
Trichomonas vaginalis PIKK family atypical protein kinase 0.0354 0.0768 0.1667
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0068 0.0122 0.1251
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0068 0.0122 0.1336
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0021 0.0015 0.0087
Trichomonas vaginalis mercuric reductase, putative 0.0033 0.0041 0.0084
Giardia lamblia Hypothetical protein 0.0068 0.0122 0.1163
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0068 0.0122 0.03
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0024 0.0022 0.0054
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0135 0.0273 0.0589
Plasmodium falciparum Appr-1-p processing domain protein 0.0042 0.0062 0.0724
Loa Loa (eye worm) CXXC zinc finger family protein 0.002 0.0012 0.0028
Mycobacterium tuberculosis Conserved hypothetical protein 0.0068 0.0122 0.0864
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0019 0.001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0154 0.0316 0.0784
Plasmodium vivax thioredoxin reductase, putative 0.0094 0.018 0.3232
Loa Loa (eye worm) glutathione reductase 0.0094 0.018 0.0445
Giardia lamblia Histone acetyltransferase GCN5 0.0025 0.0023 0.0139
Mycobacterium tuberculosis Probable dehydrogenase 0.0214 0.0452 0.3264
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0169 0.033
Brugia malayi exodeoxyribonuclease III family protein 0.0037 0.0051 0.0126
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0354 0.0768 0.153
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0101 0.0196 0.0421
Loa Loa (eye worm) cytochrome P450 family protein 0.0044 0.0067 0.0166
Trichomonas vaginalis PIKK family atypical protein kinase 0.0255 0.0544 0.1179
Onchocerca volvulus 0.0258 0.0551 0.1182
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0416 0.0909 0.2488
Brugia malayi hypothetical protein 0.0124 0.0248 0.0615
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.015
Giardia lamblia Phosphatidylinositol 4-kinase 0.0068 0.0122 0.1163
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0019 0.001 0.0012
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0019 0.001 0.0129
Trypanosoma cruzi hypothetical protein, conserved 0.1548 0.347 1
Schistosoma mansoni myelin transcription factor 1 myt1 0.0031 0.0037 0.0066
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0019 0.001 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0381 0.083 0.1804
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0135 0.0273 0.2737
Brugia malayi Pre-SET motif family protein 0.0258 0.0551 0.1366
Entamoeba histolytica cysteine protease, putative 0.0052 0.0085 0.0784
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0024 0.0022 0.002
Echinococcus granulosus muscleblind protein 0.0094 0.018 0.0177
Trypanosoma cruzi cysteine peptidase, putative 0.0384 0.0837 0.2392
Plasmodium falciparum histone acetyltransferase GCN5 0.0025 0.0023 0.0249
Trypanosoma cruzi cruzipain precursor, putative 0.0384 0.0837 0.2392
Entamoeba histolytica cysteine protease, putative 0.0052 0.0085 0.0784
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0064 0.0134
Entamoeba histolytica hypothetical protein 0.0033 0.0041 0.0329
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0004 0.0001
Echinococcus granulosus lamin 0.0027 0.0029 0.0026
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0033 0.0041 0.0101
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0019 0.001 0.0129
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0068 0.0122 0.0119
Loa Loa (eye worm) hypothetical protein 0.0094 0.018 0.0444
Mycobacterium leprae Conserved hypothetical protein 0.0021 0.0015 0.0087
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0444 0.0971 1
Echinococcus granulosus serine:threonine protein kinase SMG1 0.02 0.0419 0.0416
Treponema pallidum fructose-bisphosphate aldolase 0.0135 0.0273 1
Loa Loa (eye worm) CYP4Cod1 0.0032 0.004 0.0098
Loa Loa (eye worm) hypothetical protein 0.0042 0.0062 0.0153
Trichomonas vaginalis PIKK family atypical protein kinase 0.0255 0.0544 0.1179
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0384 0.0837 0.8615
Entamoeba histolytica cysteine protease, putative 0.0052 0.0085 0.0784
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0049 0.0078 0.0163
Plasmodium vivax vivapain-3 0.0052 0.0085 0.1503
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0049 0.0078 0.0163
Leishmania major cathepsin L-like protease 0.0384 0.0837 0.2288
Echinococcus multilocularis histone acetyltransferase MYST2 0.0031 0.0037 0.0034
Toxoplasma gondii hypothetical protein 0.0033 0.0043 0.0449
Brugia malayi Cathepsin L-like cysteine proteinase 0.0068 0.012 0.0297
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.015
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0238 0.0506 0.3657
Brugia malayi Probable ClpP-like protease 0.0074 0.0135 0.0333
Echinococcus granulosus GPCR family 2 0.0016 0.0004 0.0001
Entamoeba histolytica cysteine proteinase, putative 0.0052 0.0085 0.0784
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0068 0.0122 0.1336
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0101 0.0196 0.0421
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0019 0.001 0.0015
Entamoeba histolytica cysteine protease, putative 0.0052 0.0085 0.0784
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0051 0.0106
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0074 0.0135 0.1484
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0015 0.0014
Echinococcus multilocularis GPCR, family 2 0.0016 0.0004 0.0001
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0101 0.0196 0.0193
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.015
Toxoplasma gondii NADPH-glutathione reductase 0.0033 0.0041 0.0433
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0021 0.0016 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0101 0.0196 0.0421
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0354 0.0768 0.1904
Trichomonas vaginalis PIKK family atypical protein kinase 0.0409 0.0893 0.1939
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.001 0.0015
Plasmodium falciparum serine repeat antigen 9 0.0019 0.001 0.0086
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0101 0.0196 0.0484
Echinococcus granulosus snurportin 1 0.0188 0.0392 0.039
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0238 0.0506 0.3657
Mycobacterium ulcerans aldehyde dehydrogenase 0.0075 0.0138 0.098
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0378 0.0823 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0019 0.001 0.0015
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0033 0.0042 0.0097
Trypanosoma brucei cysteine peptidase C (CPC) 0.0019 0.001 0.0099
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0019 0.001 0.0023
Entamoeba histolytica hypothetical protein, conserved 0.0042 0.0062 0.0545
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.001 0.0015
Loa Loa (eye worm) ctsf protein 0.0101 0.0196 0.0484
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0021 0.0015 0.0087
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0021 0.0015 0.0087
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0018 0.0009 0.0000017027
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0068 0.0122 0.0236
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0017
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0027 0.0028 0.0286
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0029 0.0033 0.0069
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.015
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0048 0.0077 0.0542
Loa Loa (eye worm) hypothetical protein 0.0101 0.0196 0.0484
Loa Loa (eye worm) phosphatidylinositol kinase 0.0068 0.0122 0.03
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0033 0.0041 0.0424
Echinococcus granulosus SAM and MBT domain containing protein 0.0027 0.0028 0.0026
Loa Loa (eye worm) fibroinase 0.0101 0.0196 0.0484
Echinococcus granulosus cathepsin L 0.0052 0.0085 0.0082
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0384 0.0837 0.8615
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0018 0.0009 0.0000017027
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0021 0.0015 0.0016
Schistosoma mansoni hypothetical protein 0.0171 0.0354 0.0701
Entamoeba histolytica cysteine protease, putative 0.0052 0.0085 0.0784
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0021 0.0015 0.0087
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0069
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0068 0.0122 0.1163
Plasmodium vivax vivapain-2 0.0101 0.0196 0.3519
Plasmodium falciparum glutathione reductase 0.0094 0.018 0.216
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0024 0.0022 0.0037
Leishmania major trypanothione reductase 0.0094 0.018 0.0471
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0019 0.001 0.0012
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0019 0.001 0.0012
Entamoeba histolytica cysteine proteinase, putative 0.0101 0.0196 0.1935
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0018 0.0009 0.0000017027
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0097 0.0188 0.1933
Schistosoma mansoni microtubule-associated protein tau 0.2224 0.4997 1
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0049 0.0078 0.0163
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.02 0.0419 0.1038
Echinococcus granulosus cysteine protease 0.0052 0.0085 0.0082
Schistosoma mansoni glutaminase 0.0154 0.0316 0.0625
Brugia malayi RNA recognition motif domain containing protein 0.004 0.0057 0.0141
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0029 0.0071
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0049 0.0078 0.0163
Toxoplasma gondii hypothetical protein 0.0043 0.0064 0.069
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0135 0.0273 0.0589
Trichomonas vaginalis PIKK family atypical protein kinase 0.0131 0.0265 0.0572
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.001 0.0015
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0135 0.0273 0.2737
Loa Loa (eye worm) histone methyltransferase 0.0016 0.0003 0.0005
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0089 0.0169 0.0166
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0068 0.0122 0.03
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0015 0.0016
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0037 0.0051 0.0126
Toxoplasma gondii FATC domain-containing protein 0.02 0.0419 0.4677
Schistosoma mansoni cpg binding protein 0.0021 0.0014 0.0021
Plasmodium vivax unspecified product 0.0033 0.0043 0.0736
Schistosoma mansoni sex comb on midleg homolog 0.0027 0.0028 0.0049
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0354 0.0768 0.2193
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0075 0.0138 0.0354
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0068 0.0122 0.0119
Leishmania major cathepsin L-like protease 0.0101 0.0196 0.0515
Echinococcus granulosus intermediate filament protein 0.0027 0.0029 0.0026
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0021 0.0015 0.0087
Toxoplasma gondii LsmAD domain-containing protein 0.0124 0.0248 0.2761
Echinococcus granulosus cathepsin b 0.0019 0.001 0.0007
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0021 0.0015 0.0087
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0021 0.0015 0.0087
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0258 0.0551 0.0549
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0033 0.0041 0.028
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.02 0.0419 0.4256
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0033 0.0041 0.0038
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0024 0.0022 0.0039
Plasmodium vivax vivapain-1 0.0052 0.0085 0.1503
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0049 0.0078 0.0163
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0019 0.001 0.0012
Brugia malayi RNA binding protein 0.004 0.0057 0.0141
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0015 0.015
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0444 0.0971 0.266
Leishmania major cathepsin L-like protease 0.0101 0.0196 0.0515
Brugia malayi Appr-1-p processing enzyme family protein 0.0042 0.0062 0.0153
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0049 0.0078 0.0163
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0021 0.0015 0.0087
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0049 0.0078 0.0163
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0354 0.0768 0.0765
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0214 0.0452 0.3264
Leishmania major phosphatidylinositol kinase, putative 0.0068 0.0122 0.031
Schistosoma mansoni intermediate filament proteins 0.0027 0.0029 0.0051
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0037 0.0051 0.1099
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0037 0.0051 0.0123
Schistosoma mansoni cpg binding protein 0.0021 0.0014 0.0021
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0085 0.018
Loa Loa (eye worm) hypothetical protein 0.0033 0.0043 0.0105
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0048 0.0077 0.0542
Loa Loa (eye worm) cathepsin B 0.0019 0.001 0.0023
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0091 0.0173 0.0171
Giardia lamblia Fructose-bisphosphate aldolase 0.0135 0.0273 0.2737
Brugia malayi Papain family cysteine protease containing protein 0.0052 0.0085 0.021
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0018 0.0009 0.0000017027
Toxoplasma gondii cathepsin CPC2 0.0019 0.001 0.0079
Schistosoma mansoni lamin 0.0027 0.0029 0.0051
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0049 0.0078 0.0163
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0384 0.0837 0.8615
Schistosoma mansoni importin beta-1 0.0018 0.0007 0.0007
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0025 0.0025 0.0275
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0021 0.0015 0.0087
Mycobacterium ulcerans lipoprotein LppD 0.0042 0.0062 0.0432
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0074 0.0135 0.096
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0049 0.0078 0.0163
Echinococcus granulosus lamin dm0 0.0027 0.0029 0.0026
Entamoeba histolytica protein kinase rad3, putative 0.02 0.0419 0.4256
Trichomonas vaginalis PIKK family atypical protein kinase 0.0354 0.0768 0.1667
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0018 0.0009 0.0000017027
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0019 0.001 0.0129
Entamoeba histolytica cysteine protease, putative 0.0052 0.0085 0.0784
Trichomonas vaginalis PIKK family atypical protein kinase 0.0444 0.0971 0.211
Loa Loa (eye worm) hypothetical protein 0.0033 0.0043 0.0105
Trichomonas vaginalis PIKK family atypical protein kinase 0.0409 0.0893 0.1939
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0024 0.0022 0.0054
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0019 0.001 0.0012
Schistosoma mansoni cathepsin F (C01 family) 0.0101 0.0196 0.0384
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0101 0.0196 0.0421
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0068 0.0122 0.1163
Trichomonas vaginalis PIKK family atypical protein kinase 0.0262 0.056 0.1214
Plasmodium vivax serine-repeat antigen (SERA) 0.0019 0.001 0.0129
Trichomonas vaginalis PIKK family atypical protein kinase 0.0354 0.0768 0.1667
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.001 0.0015
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0074 0.0135 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.0082 0.0203
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0035 0.0047 0.0111
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0023
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0033 0.0041 0.0087
Trichomonas vaginalis ganglioside induced differentiation associated protein, putative 0.0042 0.0062 0.013
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0068 0.0122 0.1163
Mycobacterium leprae putative cytochrome p450 0.0021 0.0015 0.0087
Plasmodium vivax glutathione reductase, putative 0.0094 0.018 0.3232
Entamoeba histolytica deoxycytidyl transferase, putative 0.0021 0.0015 0.0051
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0021 0.0015 0.0087
Entamoeba histolytica hypothetical protein 0.0033 0.0041 0.0329
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0068 0.0122 0.0236
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0004 0.0008
Entamoeba histolytica hypothetical protein 0.02 0.0419 0.4256
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0031 0.0037 0.0034
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0135 0.0273 0.0589
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0023
Mycobacterium tuberculosis Probable reductase 0.0214 0.0452 0.3264
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0033 0.0041 0.047
Onchocerca volvulus 0.2045 0.4592 1
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0214 0.0452 0.3264
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0068 0.0122 0.0119
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0029 0.0033 0.0069
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0021 0.0015 0.0151
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0037 0.0051 0.0355
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0068 0.0122 0.0119
Trypanosoma cruzi trans-sialidase, Group I, putative 0.0018 0.0009 0.0000017027
Echinococcus granulosus tar DNA binding protein 0.004 0.0057 0.0055
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0024 0.0022 0.0043
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.015
Trypanosoma cruzi cysteine peptidase, putative 0.0033 0.0043 0.0098
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0049 0.0078 0.0075
Trypanosoma cruzi cysteine peptidase, putative 0.0384 0.0837 0.2392
Leishmania major phosphatidylinositol 3-kinase, putative 0.0068 0.0122 0.031
Schistosoma mansoni cellular tumor antigen P53 0.0099 0.0192 0.0376

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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