Detailed information for compound 75886

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 405.445 | Formula: C20H27N3O6
  • H donors: 2 H acceptors: 4 LogP: 1.14 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCC1=C(OC)C(=O)C2=C(C1=O)N1C[C@H]3[C@@H]([C@@]1([C@H]2COC(=O)N)O)N3C
  • InChi: 1S/C20H27N3O6/c1-4-5-6-7-10-15(24)14-13(16(25)17(10)28-3)11(9-29-19(21)26)20(27)18-12(22(18)2)8-23(14)20/h11-12,18,27H,4-9H2,1-3H3,(H2,21,26)/t11-,12-,18-,20+,22?/m0/s1
  • InChiKey: GGCKPTSWLUKDEX-XQGZGCQBSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus Bile acid receptor homolog 0.0057 0.0226 0.0806
Giardia lamblia Alpha-tubulin 0.0824 0.4046 0.7498
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0158 0.0727 0.135
Plasmodium vivax delta tubulin, putative 0.0282 0.1347 0.2467
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0017 0.0029 0.0032
Trichomonas vaginalis tubulin beta chain, putative 0.1093 0.5387 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.017 0.0316
Mycobacterium tuberculosis Probable metal cation transporter ATPase P-type CtpE 0.0017 0.0029 0.0032
Trypanosoma brucei epsilon tubulin 0.0615 0.3005 0.5571
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.027 0.1286 0.2387
Brugia malayi beta-lactamase 0.0037 0.0128 0.0194
Loa Loa (eye worm) hypothetical protein 0.0027 0.0076 0.0097
Leishmania major beta tubulin 0.1093 0.5387 1
Loa Loa (eye worm) sodium potassium adenosine triphosphatase 0.0032 0.0102 0.0144
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0051 0.0196 0.032
Schistosoma mansoni amine oxidase 0.0021 0.0049 0.0091
Entamoeba histolytica tubulin alpha chain, putative 0.0824 0.4046 0.7506
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0041 0.0017
Trichomonas vaginalis dynamin, putative 0.0046 0.017 0.0263
Schistosoma mansoni cation-transporting atpase 13a1 (G-box binding protein) 0.0017 0.0029 0.0053
Trypanosoma brucei alpha tubulin 0.0824 0.4046 0.7506
Giardia lamblia Potassium-transporting ATPase alpha chain 1 0.0032 0.0102 0.0136
Leishmania major carbonic anhydrase-like protein 0.0473 0.23 0.4244
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0052 0.0052
Brugia malayi follicle stimulating hormone receptor 0.0244 0.1158 0.2114
Brugia malayi Tubulin beta-1 chain 0.1093 0.5387 1
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0027 0.0076 0.0142
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0222 0.1048 0.7737
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0034 0.0111 0.0623
Toxoplasma gondii thioredoxin reductase 0.0097 0.0427 0.0751
Mycobacterium tuberculosis Probable reductase 0.0222 0.1048 0.7737
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0021 0.0045 0.0033
Leishmania major beta tubulin 0.1093 0.5387 1
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0247 0.1171 0.8664
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0038 0.0025
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0041 0.0057
Loa Loa (eye worm) hypothetical protein 0.0149 0.0687 0.1236
Loa Loa (eye worm) E1-E2 ATPase 0.0041 0.0145 0.0225
Trichomonas vaginalis tubulin alpha chain, putative 0.0333 0.1601 0.2935
Brugia malayi nuclear hormone receptor 0.0057 0.0226 0.0376
Giardia lamblia Sgs1 DNA helicase, putative 0.0018 0.0033 0.0008
Brugia malayi RNA, U transporter 1 0.0085 0.0366 0.0636
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0041 0.0057
Trichomonas vaginalis DNA helicase recq1, putative 0.0044 0.0161 0.0248
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0021 0.0049 0.0091
Mycobacterium leprae cell division protein FtsZ 0.0282 0.1347 1
Trypanosoma brucei alpha tubulin 0.0824 0.4046 0.7506
Mycobacterium ulcerans lipase LipD 0.0037 0.0128 0.0757
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0021 0.0049 0.0047
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0282 0.1347 1
Giardia lamblia Epsilon tubulin 0.0338 0.1627 0.2984
Giardia lamblia Kinase, CMGC MAPK 0.0051 0.0196 0.0312
Loa Loa (eye worm) hypothetical protein 0.0027 0.0076 0.0097
Toxoplasma gondii alpha-tubulin I, putative 0.0824 0.4046 0.75
Schistosoma mansoni intermediate filament proteins 0.0055 0.0219 0.0407
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0041 0.0076
Loa Loa (eye worm) glutathione reductase 0.0097 0.0427 0.0751
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0027 0.0076 0.0142
Schistosoma mansoni carbonic anhydrase 0.0369 0.1781 0.3307
Trichomonas vaginalis mgm1, putative 0.0046 0.017 0.0263
Schistosoma mansoni lipoxygenase 0.008 0.034 0.063
Mycobacterium ulcerans monoamine oxidase 0.0021 0.0049 0.0157
Trypanosoma cruzi UDP-galactopyranose mutase 0.0021 0.0049 0.0025
Brugia malayi glutathione reductase 0.0097 0.0427 0.0751
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0076 0.0141
Echinococcus multilocularis peroxisome assembly protein 26 0.0824 0.4046 0.7511
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0092 0.0171
Loa Loa (eye worm) tubulin alpha 2 0.0542 0.2642 0.4881
Schistosoma mansoni loxhd1 0.0019 0.0038 0.007
Onchocerca volvulus 0.0333 0.1601 0.6697
Trypanosoma brucei copper-transporting ATPase-like protein, putative 0.0017 0.0029 0.0033
Trypanosoma brucei zeta tubulin 0.0872 0.4283 0.7947
Loa Loa (eye worm) hypothetical protein 0.0057 0.0226 0.0376
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0032 0.0102 0.0189
Echinococcus multilocularis tubulin alpha chain 0.0824 0.4046 0.7511
Schistosoma mansoni type V p-type atpase isoform 0.0017 0.0029 0.0053
Schistosoma mansoni tubulin subunit beta 0.1093 0.5387 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0057 0.0226 0.0376
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0635 0.3103 0.5742
Leishmania major epsilon tubulin, putative 0.0671 0.3286 0.6082
Loa Loa (eye worm) hypothetical protein 0.0369 0.1781 0.3276
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0041 0.0057
Schistosoma mansoni tubulin subunit alpha 0.0282 0.1347 0.2501
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0057 0.0226 0.0419
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0057 0.0226 0.0376
Loa Loa (eye worm) carbonic anhydrase 3 0.0473 0.23 0.4244
Brugia malayi Tubulin gamma chain 0.0672 0.329 0.609
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0041 0.0145 0.027
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0041 0.0017
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0041 0.0017
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.003 0.0092 0.0127
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0032 0.0102 0.0168
Leishmania major alpha tubulin 0.0824 0.4046 0.75
Loa Loa (eye worm) hypothetical protein 0.0037 0.0128 0.0194
Schistosoma mansoni cation-transporting ATPase 0.0017 0.0029 0.0053
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0128 0.0186
Schistosoma mansoni ap endonuclease 0.0019 0.0035 0.0065
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.017 0.0316
Entamoeba histolytica hypothetical protein 0.0036 0.0122 0.0205
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0615 0.3005 0.5559
Loa Loa (eye worm) hypothetical protein 0.0538 0.2624 0.4849
Onchocerca volvulus Protein ultraspiracle homolog 0.0057 0.0226 0.0806
Trypanosoma brucei protein kinase, putative 0.0051 0.0196 0.0345
Echinococcus granulosus nuclear receptor nhr 48 0.0027 0.0076 0.0142
Brugia malayi hypothetical protein 0.0538 0.2624 0.4849
Echinococcus multilocularis beta tubulin 0.1093 0.5387 1
Echinococcus granulosus lysine specific histone demethylase 1A 0.0021 0.0049 0.0091
Treponema pallidum NADH oxidase 0.0034 0.0111 0.0623
Trichomonas vaginalis cation-transporting ATPase, putative 0.0041 0.0145 0.0218
Trichomonas vaginalis tubulin alpha chain, putative 0.0333 0.1601 0.2935
Loa Loa (eye worm) BEN-1 protein 0.1093 0.5387 1
Mycobacterium tuberculosis Conserved protein 0.0037 0.0128 0.0787
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0024 0.0026
Schistosoma mansoni cation-transporting atpase worm 0.0017 0.0029 0.0053
Echinococcus multilocularis musashi 0.0055 0.0219 0.0407
Echinococcus multilocularis lamin dm0 0.0055 0.0219 0.0407
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0111 0.0186
Trypanosoma brucei zeta tubulin, putative 0.0872 0.4283 0.7947
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0078 0.0333 0.2308
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0333 0.1601 0.2935
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0019 0.004 0.0085
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0041 0.0057
Brugia malayi nuclear hormone receptor family member nhr-6 0.0027 0.0076 0.0097
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0128 0.0186
Trypanosoma brucei epsilon tubulin 0.0671 0.3286 0.6092
Mycobacterium ulcerans hypothetical protein 0.0021 0.0045 0.0128
Trypanosoma brucei beta tubulin 0.1093 0.5387 1
Echinococcus granulosus Na:K ATPase alpha subunit 0.0032 0.0102 0.0189
Echinococcus multilocularis cation transporting ATPase 13A1 0.0017 0.0029 0.0053
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0051 0.0196 0.0172
Leishmania major GTP-binding protein, putative 0.0022 0.0052 0.0052
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0128 0.0186
Brugia malayi nuclear receptor RXR 0.003 0.0092 0.0127
Brugia malayi hypothetical protein 0.0027 0.0076 0.0097
Loa Loa (eye worm) hypothetical protein 0.0017 0.0029 0.0008
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0092 0.0127
Plasmodium falciparum copper-transporting ATPase 0.0017 0.0029 0.0008
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.0178 0.0331
Entamoeba histolytica dynamin-like protein 0.0046 0.017 0.0295
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0033 0.0016
Chlamydia trachomatis glutamine binding protein 0.0019 0.004 0.0366
Onchocerca volvulus 0.0029 0.0089 0.022
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0057 0.0226 0.0419
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0034 0.0111 0.0205
Giardia lamblia Beta tubulin 0.1093 0.5387 1
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0247 0.1171 0.8669
Echinococcus granulosus intermediate filament protein 0.0055 0.0219 0.0407
Trichomonas vaginalis tubulin beta chain, putative 0.0824 0.4046 0.7498
Trypanosoma brucei tubulin gamma chain 0.0672 0.329 0.61
Loa Loa (eye worm) hypothetical protein 0.0369 0.1781 0.3276
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0041 0.0127
Echinococcus granulosus phospholipid transporting ATPase IIB 0.0017 0.0029 0.0053
Trichomonas vaginalis tubulin gamma chain, putative 0.1093 0.5387 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0057 0.0226 0.0376
Loa Loa (eye worm) hypothetical protein 0.0055 0.0219 0.0363
Brugia malayi nuclear hormone receptor family member odr-7 0.0027 0.0076 0.0097
Echinococcus granulosus Tubulin alpha 1 chain 0.0824 0.4046 0.7511
Toxoplasma gondii beta tubulin 0.1093 0.5387 1
Leishmania major proton motive ATPase, putative 0.0017 0.0029 0.0008
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0024 0.0045
Schistosoma mansoni importin beta-1 0.003 0.0091 0.017
Plasmodium vivax dynamin protein, putative 0.0046 0.017 0.0271
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0039
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0038 0.007
Trypanosoma cruzi trypanothione reductase, putative 0.0034 0.0111 0.0087
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0111 0.0087
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0222 0.1048 0.7737
Echinococcus multilocularis FTZ F1 alpha 0.0057 0.0226 0.0419
Schistosoma mansoni cpg binding protein 0.0029 0.0089 0.0165
Leishmania major alpha tubulin 0.0824 0.4046 0.75
Echinococcus multilocularis beta tubulin 0.1093 0.5387 1
Echinococcus multilocularis dynamin 1 protein 0.0046 0.017 0.0315
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.017 0.0316
Echinococcus granulosus carbonic anhydrase 0.0369 0.1781 0.3307
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0035 0.002
Schistosoma mansoni ATPase 0.0041 0.0145 0.027
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0041 0.0055
Trichomonas vaginalis dynamin, putative 0.0046 0.017 0.0263
Schistosoma mansoni hypothetical protein 0.0175 0.0816 0.1515
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.0264 0.049
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0057 0.0226 0.0806
Brugia malayi beta-lactamase family protein 0.0037 0.0128 0.0194
Echinococcus multilocularis Tubulin alpha 1 chain 0.0824 0.4046 0.7511
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0111 0.0087
Brugia malayi Cell division protein ftsZ 0.0282 0.1347 0.2467
Plasmodium vivax thioredoxin reductase, putative 0.0097 0.0427 0.0751
Loa Loa (eye worm) alpha-tubulin 0.0824 0.4046 0.75
Echinococcus multilocularis thioredoxin glutathione reductase 0.0097 0.0427 0.0793
Trichomonas vaginalis dynamin, putative 0.0046 0.017 0.0263
Brugia malayi Bloom's syndrome protein homolog 0.0044 0.0161 0.0256
Mycobacterium tuberculosis Possible metal cation transporting P-type ATPase CtpH 0.0017 0.0029 0.0032
Trypanosoma cruzi alpha tubulin, putative 0.0824 0.4046 0.4032
Giardia lamblia NADH oxidase lateral transfer candidate 0.0034 0.0111 0.0153
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0035 0.002
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0034 0.0111 0.0161
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0824 0.4046 0.7498
Leishmania major hypothetical protein, conserved 0.0037 0.0128 0.0194
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0052 0.0028
Schistosoma mansoni DNA polymerase eta 0.002 0.0041 0.0076
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0033 0.0016
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0024 0.0045
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0201 0.033
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0128 0.0194
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.017 0.0316
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0062 0.0252 0.0467
Leishmania major beta tubulin 0.1093 0.5387 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0033 0.0016
Trypanosoma cruzi epsilon tubulin, putative 0.0671 0.3286 0.3269
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0021 0.0049 0.0047
Loa Loa (eye worm) hypothetical protein 0.0037 0.0128 0.0194
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0034 0.0111 0.0577
Trichomonas vaginalis tubulin epsilon chain, putative 0.0824 0.4046 0.7498
Echinococcus granulosus dynamin 1 0.0049 0.0187 0.0348
Loa Loa (eye worm) hypothetical protein 0.0047 0.0178 0.0287
Loa Loa (eye worm) hypothetical protein 0.0057 0.0226 0.0376
Echinococcus granulosus lysine specific histone demethylase 1A 0.0021 0.0049 0.0091
Brugia malayi Na,K-ATPase alpha subunit 0.0041 0.0145 0.0225
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0111 0.0161
Loa Loa (eye worm) hypothetical protein 0.0041 0.0145 0.0225
Trypanosoma brucei alpha tubulin 0.0824 0.4046 0.7506
Loa Loa (eye worm) tubulin beta chain 0.1093 0.5387 1
Loa Loa (eye worm) hypothetical protein 0.0245 0.1162 0.2121
Schistosoma mansoni hypothetical protein 0.0023 0.0059 0.0109
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0369 0.1781 0.3276
Echinococcus multilocularis carbonic anhydrase 0.0369 0.1781 0.3307
Loa Loa (eye worm) hypothetical protein 0.0037 0.0128 0.0194
Brugia malayi steroid hormone receptor 0.0057 0.0226 0.0376
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0041 0.0057
Schistosoma mansoni tubulin subunit alpha 0.0824 0.4046 0.7511
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0041 0.0145 0.0218
Plasmodium falciparum thioredoxin reductase 0.0097 0.0427 0.0751
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0473 0.23 0.4244
Leishmania major beta tubulin 0.1093 0.5387 1
Echinococcus multilocularis calcium transporting atpase 0.0032 0.0102 0.0189
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0128 0.0787
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0021 0.0049 0.0157
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0338 0.1627 0.2989
Leishmania major alpha tubulin 0.0824 0.4046 0.75
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0062 0.0252 0.0467
Echinococcus granulosus tubulin alpha 3 chain 0.0824 0.4046 0.7511
Echinococcus granulosus Tubulin beta 2C chain 0.1093 0.5387 1
Echinococcus multilocularis protoporphyrinogen oxidase 0.0021 0.0049 0.0091
Brugia malayi Fli-1 protein 0.0228 0.1076 0.1962
Trypanosoma cruzi zeta tubulin, putative 0.0872 0.4283 0.4269
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0062 0.0252 0.0424
Brugia malayi hypothetical protein 0.0245 0.1162 0.2121
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0062 0.0252 0.0467
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0027 0.0076 0.0142
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0196 0.0172
Loa Loa (eye worm) hypothetical protein 0.0021 0.0049 0.0047
Brugia malayi photoreceptor-specific nuclear receptor 0.0057 0.0226 0.0376
Brugia malayi tubulin alpha chain - mouse 0.0824 0.4046 0.75
Echinococcus multilocularis dynamin 0.0046 0.017 0.0315
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0057 0.0226 0.0376
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0111 0.0087
Entamoeba histolytica cation-transporting P-typeATPase, putative 0.0017 0.0029 0.0032
Plasmodium falciparum protoporphyrinogen oxidase 0.0021 0.0049 0.0047
Giardia lamblia Beta tubulin 0.1093 0.5387 1
Echinococcus multilocularis tubulin subunit TubB 0.0824 0.4046 0.7511
Brugia malayi hypothetical protein 0.0021 0.0049 0.0047
Giardia lamblia Beta tubulin 0.1093 0.5387 1
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0021 0.0049 0.0157
Toxoplasma gondii LsmAD domain-containing protein 0.0052 0.0201 0.033
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0114 0.051 0.0947
Schistosoma mansoni RAR-like nuclear receptor 0.0057 0.0226 0.0419
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0149 0.0687 0.1236
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0057 0.0226 0.0419
Trichomonas vaginalis tubulin beta chain, putative 0.0824 0.4046 0.7498
Loa Loa (eye worm) hypothetical protein 0.0062 0.0252 0.0424
Entamoeba histolytica hypothetical protein 0.0036 0.0122 0.0205
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.003 0.0092 0.0171
Loa Loa (eye worm) hypothetical protein 0.0057 0.0226 0.0376
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0041 0.0076
Echinococcus granulosus tubulin beta 1 chain 0.1093 0.5387 1
Echinococcus granulosus thyroid hormone receptor alpha 0.0027 0.0076 0.0142
Mycobacterium tuberculosis Probable oxidoreductase 0.0247 0.1171 0.8669
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0128 0.0238
Echinococcus granulosus tubulin alpha chain 0.0824 0.4046 0.7511
Echinococcus granulosus cation transporting ATPase 13A3 0.0017 0.0029 0.0053
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0201 0.033
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0018 0.0033 0.0061
Echinococcus multilocularis dynamin 1 0.0049 0.0187 0.0348
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0021 0.0049 0.0047
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0041 0.0145 0.027
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0018 0.0033 0.0016
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0034 0.0111 0.2699
Onchocerca volvulus 0.0488 0.2372 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0231 0.0385
Loa Loa (eye worm) tubulin alpha chain 0.0824 0.4046 0.75
Toxoplasma gondii alpha tubulin TUBA1 0.0824 0.4046 0.75
Echinococcus granulosus GPCR family 2 0.0047 0.0178 0.0331
Echinococcus multilocularis carbonic anhydrase 0.0369 0.1781 0.3307
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0196 0.0312
Mycobacterium ulcerans endonuclease IV 0.0078 0.0333 0.2307
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0041 0.0145 0.025
Schistosoma mansoni polycystin 1-related 0.0019 0.0038 0.007
Plasmodium vivax tubulin alpha chain, putative 0.0824 0.4046 0.75
Leishmania major beta tubulin 0.1093 0.5387 1
Schistosoma mansoni tubulin subunit beta 0.1093 0.5387 1
Brugia malayi Dynamin 0.0049 0.0187 0.0304
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0034 0.0111 0.0161
Brugia malayi Ets-domain containing protein 0.0075 0.0316 0.0544
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0034 0.0111 0.0577
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0057 0.0226 0.0376
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0128 0.0238
Echinococcus granulosus dna polymerase kappa 0.002 0.0041 0.0076
Trichomonas vaginalis conserved hypothetical protein 0.0282 0.1347 0.2461
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0051 0.0196 0.032
Trypanosoma brucei unspecified product 0.002 0.0041 0.0057
Brugia malayi E1-E2 ATPase family protein 0.0041 0.0145 0.0225
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0034 0.0111 0.0161
Onchocerca volvulus 0.0041 0.0145 0.046
Loa Loa (eye worm) hypothetical protein 0.0027 0.0076 0.0097
Leishmania major P-type ATPase, putative 0.0032 0.0102 0.0144
Trypanosoma cruzi dynamin-1-like protein 0.0046 0.017 0.0146
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0051 0.0196 0.0172
Brugia malayi Thioredoxin reductase 0.0097 0.0427 0.0751
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0057 0.0226 0.0419
Loa Loa (eye worm) hypothetical protein 0.0037 0.0128 0.0194
Plasmodium falciparum calcium-transporting ATPase 0.0032 0.0102 0.0144
Brugia malayi tailless protein 0.0027 0.0076 0.0097
Plasmodium vivax tubulin epsilon chain, putative 0.0671 0.3286 0.6082
Schistosoma mansoni lamin 0.0055 0.0219 0.0407
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0057 0.0226 0.0376
Brugia malayi hypothetical protein 0.003 0.0092 0.0127
Schistosoma mansoni tubulin subunit gamma 0.0672 0.329 0.6107
Loa Loa (eye worm) hypothetical protein 0.0057 0.0226 0.0376
Trichomonas vaginalis tubulin epsilon chain, putative 0.1093 0.5387 1
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0091 0.0124
Echinococcus granulosus importin subunit beta 1 0.003 0.0091 0.017
Loa Loa (eye worm) beta-tubulin 0.1093 0.5387 1
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0035 0.0081
Echinococcus granulosus carbonic anhydrase 0.0369 0.1781 0.3307
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0057 0.0226 0.0376
Toxoplasma gondii dynamin-related protein DRPB 0.0046 0.017 0.0271
Chlamydia trachomatis endonuclease IV 0.0078 0.0333 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0057 0.0226 0.0419
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0027 0.0076 0.0142
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0032 0.0102 0.0189
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0041 0.0127
Loa Loa (eye worm) intermediate filament protein 0.0055 0.0219 0.0363
Echinococcus multilocularis Tubulin beta 2C chain 0.1093 0.5387 1
Trypanosoma brucei dynamin-1-like protein 0.0046 0.017 0.0296
Schistosoma mansoni carbonic anhydrase-related 0.0369 0.1781 0.3307
Brugia malayi ecdysone receptor 0.0027 0.0076 0.0097
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0128 0.0787
Echinococcus granulosus peroxisome assembly protein 26 0.0824 0.4046 0.7511
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.003 0.0091 0.0124
Schistosoma mansoni alpha tubulin 0.0824 0.4046 0.7511
Echinococcus granulosus survival motor neuron protein 1 0.0245 0.1162 0.2157
Brugia malayi Membrane calcium atpase protein 3 0.0032 0.0102 0.0144
Schistosoma mansoni calcium-transporting atpase 2 (atpase 2) 0.0032 0.0102 0.0189
Leishmania major beta tubulin 0.1093 0.5387 1
Plasmodium falciparum dynamin-like protein 0.0046 0.017 0.0271
Loa Loa (eye worm) hypothetical protein 0.0027 0.0076 0.0097
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0063 0.0039
Loa Loa (eye worm) hypothetical protein 0.0023 0.0059 0.0066
Brugia malayi MAP kinase sur-1 0.0051 0.0196 0.032
Schistosoma mansoni nuclear receptor 0.0027 0.0076 0.0142
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0369 0.1781 0.3276
Trichomonas vaginalis dynamin, putative 0.0046 0.017 0.0263
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0196 0.0312
Schistosoma mansoni hypothetical protein 0.0047 0.0178 0.0331
Brugia malayi intermediate filament protein 0.0055 0.0219 0.0363
Schistosoma mansoni rab6-interacting 0.0019 0.0038 0.007
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0039 0.0135 0.0206
Echinococcus granulosus lamin 0.0055 0.0219 0.0407
Treponema pallidum cell division protein FtsZ 0.0282 0.1347 1
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0035 0.0065
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0057 0.0226 0.0419
Echinococcus multilocularis neuropeptide s receptor 0.0485 0.2359 0.4379
Echinococcus multilocularis GPCR, family 2 0.0047 0.0178 0.0331
Echinococcus granulosus Tubulin beta 2C chain 0.1093 0.5387 1
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.027 0.1286 0.2387
Echinococcus granulosus calcium transporting atpase 0.0032 0.0102 0.0189
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0051 0.0196 0.0345
Loa Loa (eye worm) hypothetical protein 0.0023 0.0059 0.0066
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0021 0.0049 0.0157
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.003 0.0092 0.0171
Loa Loa (eye worm) hypothetical protein 0.0078 0.0333 0.0575
Trypanosoma cruzi tubulin delta chain 0.0635 0.3103 0.3087
Loa Loa (eye worm) hypothetical protein 0.0057 0.0226 0.0376
Echinococcus granulosus dna polymerase eta 0.002 0.0041 0.0076
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0017 0.0029 0.0004
Loa Loa (eye worm) hypothetical protein 0.0021 0.0049 0.0047
Schistosoma mansoni DNA helicase recq1 0.0018 0.0033 0.0061
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0057 0.0226 0.0376
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0041 0.0031
Echinococcus granulosus tubulin alpha chain 0.0824 0.4046 0.7511
Trypanosoma brucei P-type H+-ATPase, putative 0.0079 0.0336 0.0606
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.006 0.0058
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0041 0.0145 0.027
Entamoeba histolytica tubulin family protein 0.1093 0.5387 1
Plasmodium vivax tubulin gamma chain, putative 0.0672 0.329 0.609
Leishmania major alpha tubulin 0.0824 0.4046 0.75
Echinococcus multilocularis tubulin alpha chain 0.0824 0.4046 0.7511
Brugia malayi SWIRM domain containing protein 0.0021 0.0049 0.0047
Leishmania major alpha tubulin 0.0824 0.4046 0.75
Giardia lamblia Alpha-tubulin 0.0824 0.4046 0.7498
Schistosoma mansoni steroid hormone receptor ad4bp 0.0057 0.0226 0.0419
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0034 0.0111 0.0623
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.0178 0.0287
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0035 0.002
Echinococcus multilocularis Tubulin beta 2C chain 0.1093 0.5387 1
Trichomonas vaginalis DNA helicase recq, putative 0.0044 0.0161 0.0248
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0059 0.0109
Toxoplasma gondii dynamin-related protein DRPA 0.0046 0.017 0.0271
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0128 0.0238
Toxoplasma gondii P-type ATPase4, putative 0.0041 0.0145 0.0225
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0024 0.0045
Onchocerca volvulus 0.0037 0.0128 0.0389
Loa Loa (eye worm) fli-1 protein 0.0228 0.1076 0.1962
Schistosoma mansoni lamin 0.0055 0.0219 0.0407
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0018 0.0033 0.0016
Trichomonas vaginalis tubulin beta chain, putative 0.0824 0.4046 0.7498
Loa Loa (eye worm) hypothetical protein 0.0064 0.0262 0.0443
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0051 0.0196 0.032
Loa Loa (eye worm) hypothetical protein 0.0021 0.0049 0.0047
Schistosoma mansoni hypothetical protein 0.0047 0.0178 0.0331
Schistosoma mansoni tubulin subunit epsilon 0.0671 0.3286 0.61
Brugia malayi hypothetical protein 0.0036 0.0122 0.0181
Echinococcus multilocularis mitogen activated protein kinase 3 0.0051 0.0196 0.0364
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0041 0.0145 0.0225
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0038 0.007
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0091 0.0124
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0017 0.0029 0.0008
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0041 0.0145 0.0249
Loa Loa (eye worm) hypothetical protein 0.0057 0.0226 0.0376
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0128 0.0238
Trichomonas vaginalis dynamin, putative 0.0046 0.017 0.0263
Brugia malayi potential phospholipid-transporting ATPase IIB, putative 0.0017 0.0029 0.0008
Onchocerca volvulus 0.0021 0.0049 0.0049
Echinococcus granulosus beta tubulin 0.1093 0.5387 1
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0473 0.23 0.2281
Trypanosoma brucei epsilon tubulin 0.0671 0.3286 0.6092
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0041 0.0057
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0027 0.0076 0.0165
Echinococcus multilocularis RUN 0.0019 0.0038 0.007
Brugia malayi hypothetical protein 0.0019 0.0038 0.0025
Leishmania major importin beta-1 subunit, putative 0.0024 0.0063 0.0073
Echinococcus granulosus cation transporting atpase worm 0.0017 0.0029 0.0053
Loa Loa (eye worm) DRP-1 protein 0.0046 0.017 0.0271
Echinococcus multilocularis neuropeptide receptor A26 0.0485 0.2359 0.4379
Schistosoma mansoni hypothetical protein 0.0319 0.153 0.284
Loa Loa (eye worm) nuclear hormone receptor 0.0027 0.0076 0.0097
Trypanosoma cruzi epsilon tubulin, putative 0.0671 0.3286 0.3269
Echinococcus multilocularis Tubulin alpha 1 chain 0.0824 0.4046 0.7511
Loa Loa (eye worm) hypothetical protein 0.0027 0.0076 0.0097
Leishmania major alpha tubulin 0.0824 0.4046 0.75
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0052 0.0052
Schistosoma mansoni dynamin 0.0049 0.0187 0.0348
Brugia malayi conserved hypotetical protein 0.0027 0.0076 0.0097
Trypanosoma brucei calcium motive p-type ATPase, putative 0.0032 0.0102 0.0169
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0196 0.0312
Brugia malayi Tubulin alpha-2 chain 0.0824 0.4046 0.75
Trypanosoma brucei alpha tubulin 0.0824 0.4046 0.7506
Trypanosoma cruzi plasma-membrane proton-efflux P-type ATPase, putative 0.007 0.0293 0.0269
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0057 0.0226 0.0419
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0473 0.23 0.4244
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0429 0.2078 0.383
Echinococcus multilocularis tubulin subunit beta 0.1093 0.5387 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.0326 0.1569 0.2912
Loa Loa (eye worm) hypothetical protein 0.0021 0.0049 0.0047
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0089 0.012
Trichomonas vaginalis tubulin alpha chain, putative 0.0333 0.1601 0.2935
Echinococcus granulosus Tubulin alpha 1 chain 0.0824 0.4046 0.7511
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0057 0.0226 0.0376
Echinococcus multilocularis Ca2+ transporting ATPase plasma membrane 0.0032 0.0102 0.0189
Echinococcus granulosus neuropeptide s receptor 0.0485 0.2359 0.4379
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0025 0.0066 0.0078
Schistosoma mansoni retinoic acid receptor RXR 0.0158 0.0727 0.135
Brugia malayi orphan nuclear receptor NR2E1 0.0027 0.0076 0.0097
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0041 0.0145 0.0225
Echinococcus multilocularis lamin 0.0055 0.0219 0.0407
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.0127
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0024 0.0045
Schistosoma mansoni gabp alpha 0.0075 0.0316 0.0587
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0041 0.0145 0.0121
Schistosoma mansoni dynamin 0.0046 0.017 0.0315
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0128 0.0787
Echinococcus granulosus Tubulin beta 2C chain 0.1093 0.5387 1
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0041 0.0076
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0034 0.0111 0.0186
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0052 0.0052
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0052 0.0097
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0473 0.23 0.427
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0057 0.0226 0.0419
Schistosoma mansoni ran 0.0022 0.0052 0.0097
Mycobacterium tuberculosis Possible oxidoreductase 0.0021 0.0049 0.0189
Trypanosoma cruzi proton motive ATPase, putative 0.0038 0.0134 0.011
Loa Loa (eye worm) hypothetical protein 0.0027 0.0076 0.0097
Echinococcus multilocularis tubulin alpha 3 chain 0.0824 0.4046 0.7511
Onchocerca volvulus 0.0055 0.0219 0.0777
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0057 0.0226 0.0376
Trypanosoma cruzi trypanothione reductase, putative 0.0097 0.0427 0.0404
Leishmania major alpha tubulin 0.0824 0.4046 0.75
Leishmania major P-type H -ATPase, putative 0.0079 0.0336 0.0582
Leishmania major calcium motive p-type ATPase, putative 0.0032 0.0102 0.0144
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0041 0.0031
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0035 0.0011
Mycobacterium leprae Probable lipase LipE 0.0037 0.0128 0.0757
Trichomonas vaginalis tubulin alpha chain, putative 0.0615 0.3005 0.5556
Echinococcus granulosus tubulin alpha 1C chain 0.0824 0.4046 0.7511
Loa Loa (eye worm) hypothetical protein 0.1024 0.5042 0.9357
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0041 0.0145 0.0121
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0041 0.0145 0.027
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0057 0.0226 0.0419
Echinococcus multilocularis ecdysone induced protein 78C 0.0057 0.0226 0.0419
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0473 0.23 0.2281
Echinococcus granulosus geminin 0.0175 0.0816 0.1515
Schistosoma mansoni blooms syndrome DNA helicase 0.0035 0.0115 0.0214
Brugia malayi hypothetical protein 0.0027 0.0076 0.0097
Schistosoma mansoni survival motor neuron protein 0.005 0.0191 0.0355
Brugia malayi Sodium/potassium-transporting ATPase alpha-3 chain, putative 0.0032 0.0102 0.0144
Echinococcus granulosus Tubulin beta 2C chain 0.1093 0.5387 1
Echinococcus granulosus RUN 0.0019 0.0038 0.007
Schistosoma mansoni ran 0.0022 0.0052 0.0097
Plasmodium falciparum carbonic anhydrase 0.0369 0.1781 0.3276
Loa Loa (eye worm) hypothetical protein 0.0037 0.0128 0.0194
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0091 0.015
Trichomonas vaginalis ran, putative 0.0022 0.0052 0.0044
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0049 0.0047
Entamoeba histolytica tubulin family protein 0.1093 0.5387 1
Trypanosoma brucei cation-transporting ATPase, putative 0.0017 0.0029 0.0033
Loa Loa (eye worm) hypothetical protein 0.002 0.0041 0.0031
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0041 0.0145 0.027
Brugia malayi hypothetical protein 0.0033 0.011 0.0159
Loa Loa (eye worm) hypothetical protein 0.0037 0.0128 0.0194
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0063 0.0065
Trichomonas vaginalis tubulin beta chain, putative 0.0824 0.4046 0.7498
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0017 0.0029 0.0008
Loa Loa (eye worm) tubulin alpha 2 0.0209 0.0983 0.1789
Schistosoma mansoni cation-transporting atpase worm 0.0017 0.0029 0.0053
Echinococcus multilocularis phospholipid transporting ATPase IIB 0.0017 0.0029 0.0053
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.0041 0.0145 0.0884
Trichomonas vaginalis cation-transporting ATPase, putative 0.0041 0.0145 0.0218
Echinococcus multilocularis tubulin epsilon chain 0.0671 0.3286 0.61
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0201 0.0177
Schistosoma mansoni ATPase 0.0041 0.0145 0.027
Giardia lamblia Gamma tubulin 0.0672 0.329 0.6087
Brugia malayi Pre-SET motif family protein 0.0062 0.0252 0.0424
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0034 0.0111 0.0161
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0057 0.0226 0.0419
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0075 0.0316 0.0544
Schistosoma mansoni thyroid hormone receptor 0.0326 0.1569 0.2912
Echinococcus granulosus tubulin alpha chain 0.0824 0.4046 0.7511
Echinococcus granulosus snurportin 1 0.0319 0.153 0.284
Toxoplasma gondii ABC1 family protein 0.0037 0.0128 0.0194
Brugia malayi Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0032 0.0102 0.0144
Onchocerca volvulus 0.0055 0.0219 0.0777
Brugia malayi Dynamin 0.0049 0.0187 0.0304
Echinococcus granulosus carbonic anhydrase II 0.0473 0.23 0.427
Schistosoma mansoni tubulin subunit beta 0.0282 0.1347 0.2501
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0201 0.0177
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.017 0.0316
Onchocerca volvulus 0.0027 0.0076 0.0165
Mycobacterium ulcerans dehydrogenase 0.0021 0.0049 0.0157
Echinococcus granulosus dynamin 1 protein 0.0046 0.017 0.0315
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0128 0.0787
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0252 0.0467
Schistosoma mansoni nuclear hormone receptor 0.0027 0.0076 0.0142
Echinococcus granulosus tubulin beta 4A class IVa 0.1093 0.5387 1
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0027 0.0076 0.0142
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0282 0.1347 0.2461
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0057 0.0226 0.0419
Leishmania major beta tubulin 0.1093 0.5387 1
Entamoeba histolytica recQ family helicase, putative 0.0023 0.006 0.009
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0032 0.0102 0.0078
Brugia malayi Latrophilin receptor protein 2 0.0047 0.0178 0.0287
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0023 0.0058 0.0063
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0128 0.0104
Echinococcus granulosus Tubulin beta 2C chain 0.1093 0.5387 1
Trichomonas vaginalis set domain proteins, putative 0.0488 0.2372 0.4374
Mycobacterium tuberculosis Conserved protein 0.0037 0.0128 0.0787
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0019 0.004 0.0117
Brugia malayi alpha-tubulin 0.0824 0.4046 0.75
Loa Loa (eye worm) hypothetical protein 0.0102 0.0452 0.0797
Trichomonas vaginalis tubulin gamma chain, putative 0.0671 0.3286 0.6079
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0038 0.0025
Echinococcus multilocularis tubulin alpha 1C chain 0.0824 0.4046 0.7511
Loa Loa (eye worm) tubulin alpha-3 chain 0.0491 0.2388 0.4407
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0041 0.0145 0.0225
Loa Loa (eye worm) tubulin gamma chain 0.0672 0.329 0.609
Loa Loa (eye worm) tubulin alpha-2 chain 0.0824 0.4046 0.75
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0041 0.0031
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0092 0.0127
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0018 0.0033 0.0061
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0252 0.0467
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0369 0.1781 0.3276
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0057 0.0226 0.0419
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0128 0.0787
Leishmania major beta tubulin 0.1093 0.5387 1
Echinococcus multilocularis hypothetical protein 0.0824 0.4046 0.7511
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0542 0.2642 0.4877
Echinococcus granulosus alpha tubulin 0.0824 0.4046 0.7511
Loa Loa (eye worm) hypothetical protein 0.0017 0.0029 0.0008
Echinococcus multilocularis survival motor neuron protein 1 0.0245 0.1162 0.2157
Schistosoma mansoni carbonic anhydrase-related 0.0369 0.1781 0.3307
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0041 0.0057
Trypanosoma cruzi proton motive ATPase 1, putative 0.0038 0.0134 0.011
Toxoplasma gondii endonuclease IV APN 0.0078 0.0333 0.0575
Echinococcus multilocularis tubulin delta chain 0.0282 0.1347 0.2501
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.0127
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0057 0.0226 0.0376
Echinococcus granulosus dnaJ subfamily B 0.0418 0.2024 0.3758
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0035 0.002
Toxoplasma gondii tubulin, putative 0.0056 0.0223 0.0371
Entamoeba histolytica tubulin gamma chain 0.0672 0.329 0.6099
Leishmania major calcium-translocating P-type ATPase 0.0041 0.0145 0.0225
Loa Loa (eye worm) hypothetical protein 0.0019 0.0038 0.0025
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0033 0.0016
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.0178 0.0331
Mycobacterium tuberculosis Conserved protein 0.0037 0.0128 0.0787
Schistosoma mansoni alpha tubulin 0.0824 0.4046 0.7511
Echinococcus granulosus tubulin alpha 1C chain 0.0824 0.4046 0.7511
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0057 0.0226 0.0376
Trypanosoma brucei PAB1-binding protein , putative 0.0052 0.0201 0.0354
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0057 0.0226 0.0419
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0128 0.0194
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0024 0.0026
Trichomonas vaginalis esterase, putative 0.0037 0.0128 0.0186
Plasmodium falciparum dynamin-like protein 0.0046 0.017 0.0271
Echinococcus multilocularis carbonic anhydrase 0.0369 0.1781 0.3307
Schistosoma mansoni na+/k+ atpase alpha subunit 0.0032 0.0102 0.0189
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0222 0.1048 0.7737
Trypanosoma cruzi cation-transporting ATPase, putative 0.0017 0.0029 0.0004
Loa Loa (eye worm) tubulin beta-4 chain 0.1093 0.5387 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0187 0.0304
Leishmania major calcium-transporting ATPase, putative 0.0032 0.0102 0.0144
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.0041 0.0145 0.0249
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0041 0.0145 0.027
Loa Loa (eye worm) tubulin beta-2A chain 0.1093 0.5387 1
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0078 0.0333 0.0575
Schistosoma mansoni ap endonuclease 0.0019 0.0035 0.0065
Echinococcus multilocularis mitogen activated protein kinase 0.0051 0.0196 0.0364
Leishmania major gamma-tubulin 0.0672 0.329 0.609
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0091 0.0125
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0542 0.2642 0.4881
Echinococcus multilocularis tubulin, beta 4A class IVa 0.1093 0.5387 1
Toxoplasma gondii dynamin gtpase 0.003 0.0092 0.0127
Echinococcus granulosus beta tubulin 0.1093 0.5387 1
Trypanosoma brucei tubulin delta chain 0.0635 0.3103 0.5753
Schistosoma mansoni tubulin subunit beta 0.1093 0.5387 1
Leishmania major beta tubulin 0.1093 0.5387 1
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase CtpV 0.0017 0.0029 0.0032
Trypanosoma brucei alpha tubulin, putative 0.0333 0.1601 0.2959
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0076 0.0141
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0027 0.0076 0.0165
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0021 0.0049 0.0091
Schistosoma mansoni coup transcription factor 0.0057 0.0226 0.0419
Echinococcus multilocularis tubulin alpha chain 0.0824 0.4046 0.7511
Brugia malayi nuclear receptor NHR-88 0.0027 0.0076 0.0097
Loa Loa (eye worm) hypothetical protein 0.0035 0.0117 0.0173
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0111 0.0186
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0128 0.0104
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0051 0.0196 0.032
Loa Loa (eye worm) hypothetical protein 0.0027 0.0076 0.0097
Trichomonas vaginalis tubulin beta chain, putative 0.0824 0.4046 0.7498
Loa Loa (eye worm) hypothetical protein 0.0021 0.0049 0.0047
Brugia malayi nuclear receptor RXR 0.0027 0.0076 0.0097
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0128 0.0578 0.1073
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0319 0.153 0.2807
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0041 0.0145 0.0249
Loa Loa (eye worm) hypothetical protein 0.0027 0.0076 0.0097
Schistosoma mansoni ets-related 0.0228 0.1076 0.1998
Plasmodium falciparum glutathione reductase 0.0034 0.0111 0.0161
Echinococcus granulosus tubulin delta chain 0.0282 0.1347 0.2501
Brugia malayi Tubulin beta chain 0.0282 0.1347 0.2467
Plasmodium vivax importin-beta 2, putative 0.003 0.0091 0.0125
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0052 0.0078
Echinococcus granulosus Nuclear hormone receptor HR96 0.0027 0.0076 0.0142
Echinococcus granulosus Nuclear hormone receptor HR96 0.0027 0.0076 0.0142
Echinococcus granulosus mitogen activated protein kinase 3 0.0051 0.0196 0.0364
Plasmodium falciparum alpha tubulin 1 0.0824 0.4046 0.75
Trichomonas vaginalis dynamin, putative 0.0046 0.017 0.0263
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0035 0.0011
Brugia malayi Intermediate filament tail domain containing protein 0.0055 0.0219 0.0363
Brugia malayi hypothetical protein 0.003 0.0092 0.0127
Leishmania major beta tubulin 0.1093 0.5387 1
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0021 0.0049 0.0047
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0128 0.0194
Loa Loa (eye worm) tubulin beta chain 0.0282 0.1347 0.2467
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0034 0.0111 0.0623
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0024 0.0045
Toxoplasma gondii hypothetical protein 0.0369 0.1781 0.3276
Echinococcus granulosus dynamin 0.0046 0.017 0.0315
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0369 0.1781 0.3276
Plasmodium vivax P-type ATPase4, putative 0.0041 0.0145 0.0225
Entamoeba histolytica dynamin-1-like protein, putative 0.0046 0.017 0.0295
Leishmania major beta tubulin 0.1093 0.5387 1
Trypanosoma cruzi tubulin delta chain 0.0635 0.3103 0.3087
Loa Loa (eye worm) hypothetical protein 0.0824 0.4046 0.75
Loa Loa (eye worm) hypothetical protein 0.0019 0.0038 0.0025
Trypanosoma cruzi UDP-galactopyranose mutase 0.0021 0.0049 0.0025
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0369 0.1781 0.3276
Entamoeba histolytica hypothetical protein 0.0024 0.0063 0.0097
Leishmania major UDP-galactopyranose mutase 0.0021 0.0049 0.0047
Echinococcus multilocularis importin subunit beta 1 0.003 0.0091 0.017
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0128 0.0219
Brugia malayi Probable cation-transporting ATPase C10C6.6 in chromosome IV 0.0017 0.0029 0.0008
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0025 0.0066 0.0078
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0041 0.0145 0.0225
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0111 0.0087
Loa Loa (eye worm) hypothetical protein 0.0026 0.0071 0.0087
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0021 0.0045 0.0128
Schistosoma mansoni nuclear receptor nhr-48 0.0027 0.0076 0.0142
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0034 0.0111 0.0186
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0049 0.0189
Echinococcus granulosus plasma membrane calcium transporting ATPase 0.0032 0.0102 0.0189
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.006 0.0091
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0038 0.007
Toxoplasma gondii NADPH-glutathione reductase 0.0034 0.0111 0.0161
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0038 0.007
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0032 0.0102 0.0078
Schistosoma mansoni amine oxidase 0.0021 0.0049 0.0091
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.0178 0.0331
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0041 0.0145 0.0218
Echinococcus multilocularis bloom syndrome protein 0.0044 0.0161 0.03
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0052 0.0028
Trypanosoma cruzi beta tubulin, putative 0.1093 0.5387 0.5375
Giardia lamblia Dynamin 0.0046 0.017 0.0263
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0041 0.0145 0.0884
Schistosoma mansoni hypothetical protein 0.0369 0.1781 0.3307
Echinococcus multilocularis tubulin alpha 3 chain 0.0824 0.4046 0.7511
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0128 0.0186
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0041 0.0145 0.025
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0035 0.0012
Leishmania major DNA polymerase kappa, putative 0.002 0.0041 0.0031
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0038 0.0025
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0111 0.0087
Leishmania major beta tubulin 0.1093 0.5387 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0034 0.0111 0.0161
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0111 0.0087
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0247 0.1171 0.8669
Brugia malayi hypothetical protein 0.0052 0.0201 0.033
Loa Loa (eye worm) tubulin beta-1 chain 0.1093 0.5387 1
Echinococcus multilocularis plasma membrane calcium transporting ATPase 0.0032 0.0102 0.0189
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0041 0.0145 0.0249
Echinococcus granulosus nmda type glutamate receptor 0.0027 0.0077 0.0144
Trichomonas vaginalis tubulin beta chain, putative 0.0824 0.4046 0.7498
Toxoplasma gondii beta-tubulin, putative 0.1093 0.5387 1
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0034 0.0111 0.0161
Schistosoma mansoni rab6-interacting 0.0019 0.0038 0.007
Echinococcus granulosus mitogen activated protein kinase 0.0051 0.0196 0.0364
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0057 0.0226 0.0376
Trichomonas vaginalis mercuric reductase, putative 0.0034 0.0111 0.0153
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0091 0.015
Echinococcus granulosus cpg binding protein 0.0031 0.0097 0.0181
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0035 0.0065
Toxoplasma gondii exonuclease III APE 0.0019 0.0035 0.002
Echinococcus multilocularis nmda type glutamate receptor 0.0027 0.0077 0.0144
Leishmania major copper-transporting ATPase-like protein, putative 0.0017 0.0029 0.0008
Schistosoma mansoni thyroid hormone receptor 0.0326 0.1569 0.2912
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0041 0.0145 0.027
Schistosoma mansoni hypothetical protein 0.0019 0.0038 0.007
Plasmodium vivax cation transporting ATPase, putative 0.0017 0.0029 0.0008
Schistosoma mansoni hypothetical protein 0.0047 0.0178 0.0331
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0491 0.2388 0.4403
Trichomonas vaginalis tubulin, putative 0.0333 0.1601 0.2935
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0057 0.0226 0.0376
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0122 0.0226
Loa Loa (eye worm) tubulin alpha 2 0.0542 0.2642 0.4881
Brugia malayi Steroid receptor seven-up type 2 0.0057 0.0226 0.0376
Trypanosoma brucei beta tubulin 0.1093 0.5387 1
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0035 0.0012
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0041 0.0031
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0041 0.0145 0.0218
Loa Loa (eye worm) hypothetical protein 0.0021 0.0049 0.0047
Brugia malayi Pre-SET motif family protein 0.0429 0.2078 0.383
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0041 0.0145 0.0218
Schistosoma mansoni tubulin subunit alpha 0.0824 0.4046 0.7511
Trypanosoma brucei trypanothione reductase 0.0097 0.0427 0.0775
Loa Loa (eye worm) steroid hormone receptor 0.0057 0.0226 0.0376
Loa Loa (eye worm) hypothetical protein 0.0017 0.0029 0.0008
Plasmodium vivax ataxin-2 like protein, putative 0.0052 0.0201 0.033
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0114 0.051 0.0947
Brugia malayi Tubulin alpha-2 chain 0.0824 0.4046 0.75
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0035 0.002
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0034 0.0111 0.0205
Brugia malayi Nuclear hormone receptor E75 0.0027 0.0076 0.0097
Leishmania major alpha tubulin 0.0824 0.4046 0.75
Loa Loa (eye worm) hypothetical protein 0.0054 0.0214 0.0354
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0019 0.004 0.0085
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0128 0.0757
Trichomonas vaginalis tubulin, putative 0.1093 0.5387 1
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.003 0.0092 0.0171
Trichomonas vaginalis tubulin gamma chain, putative 0.0282 0.1347 0.2461
Schistosoma mansoni cpg binding protein 0.0031 0.0097 0.0181
Echinococcus granulosus FTZ F1 alpha 0.0057 0.0226 0.0419
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0057 0.0226 0.0376
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0369 0.1781 0.3276
Schistosoma mansoni cpg binding protein 0.0031 0.0097 0.0181
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0035 0.0044
Loa Loa (eye worm) tubulin alpha chain 0.0824 0.4046 0.75
Trypanosoma cruzi P-type H+-ATPase, putative 0.0079 0.0336 0.0313
Loa Loa (eye worm) DR-78 0.0027 0.0076 0.0097
Schistosoma mansoni tubulin subunit beta 0.1093 0.5387 1
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0035 0.0049
Toxoplasma gondii plasma membrane-type Ca(2+)-ATPase A1 PMCAA1 0.0032 0.0102 0.0144
Brugia malayi nuclear receptor NHR-88 0.0057 0.0226 0.0376
Trichomonas vaginalis tubulin beta chain, putative 0.0333 0.1601 0.2935
Toxoplasma gondii beta-1 tubulin, putative 0.1093 0.5387 1
Schistosoma mansoni hypothetical protein 0.027 0.1286 0.2387
Echinococcus multilocularis tubulin alpha 0.0615 0.3005 0.5579
Echinococcus granulosus cation transporting ATPase 13A1 0.0017 0.0029 0.0053
Echinococcus multilocularis GA binding protein alpha chain 0.0075 0.0316 0.0587
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0038 0.007
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0035 0.0012
Trichomonas vaginalis cation-transporting ATPase, putative 0.0041 0.0145 0.0218
Entamoeba histolytica tubulin alpha-1 chain 0.0824 0.4046 0.7506
Leishmania major GTP-binding protein, putative 0.0046 0.017 0.0271
Echinococcus granulosus tubulin alpha chain 0.0824 0.4046 0.7511
Mycobacterium tuberculosis Cation transporter P-type ATPase a CtpA 0.0017 0.0029 0.0032
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0052 0.0052
Echinococcus multilocularis 0.0021 0.0049 0.0091
Loa Loa (eye worm) BEN-1 protein 0.1093 0.5387 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0071 0.0087
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0017 0.0029 0.0008
Brugia malayi Dynamin central region family protein 0.0046 0.017 0.0271
Schistosoma mansoni zinc finger protein 0.0027 0.0076 0.0142
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0038 0.007
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0222 0.1048 0.7737
Schistosoma mansoni DNA helicase recq5 0.0018 0.0033 0.0061
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0052 0.0052
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0238 0.1129 0.8348
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0063 0.0065
Leishmania major hypothetical protein, conserved 0.0052 0.0201 0.033
Brugia malayi Importin beta-1 subunit 0.003 0.0091 0.0125
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0027 0.0076 0.0097
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0128 0.0757
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0017 0.0029 0.0004
Trichomonas vaginalis tubulin epsilon chain, putative 0.0282 0.1347 0.2461
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0057 0.0226 0.0376
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0041 0.0017
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0089 0.0121
Plasmodium falciparum tubulin epsilon chain, putative 0.0671 0.3286 0.6082
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.0127
Trypanosoma brucei beta tubulin 0.1093 0.5387 1
Echinococcus granulosus tubulin gamma 1 chain 0.0672 0.329 0.6107
Plasmodium falciparum tubulin beta chain 0.1093 0.5387 1
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0041 0.0023
Plasmodium falciparum importin beta, putative 0.003 0.0091 0.0125
Echinococcus multilocularis Tubulin beta 2C chain 0.1093 0.5387 1
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0032 0.0102 0.0189
Toxoplasma gondii histone lysine-specific demethylase 0.0021 0.0049 0.0047
Leishmania major alpha tubulin 0.0824 0.4046 0.75
Leishmania major trypanothione reductase 0.0097 0.0427 0.0751
Echinococcus multilocularis tubulin alpha chain 0.0824 0.4046 0.7511
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0032 0.0102 0.0136
Brugia malayi ecdysteroid receptor 0.0057 0.0226 0.0376
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0045 0.016
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0111 0.0087
Leishmania major beta tubulin 0.1093 0.5387 1
Trypanosoma cruzi zeta tubulin, putative 0.0872 0.4283 0.4269
Mycobacterium ulcerans hypothetical protein 0.0037 0.0128 0.0757
Leishmania major beta tubulin 0.1093 0.5387 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0076 0.0097
Brugia malayi Doublecortin family protein 0.0019 0.0038 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0057 0.0226 0.0376
Leishmania major beta tubulin 0.1093 0.5387 1
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0035 0.0049
Echinococcus multilocularis Tubulin alpha 1 chain 0.0824 0.4046 0.7511
Echinococcus granulosus neuropeptide receptor A26 0.0485 0.2359 0.4379
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0024 0.0045
Schistosoma mansoni tubulin subunit delta 0.0282 0.1347 0.2501
Brugia malayi Tubulin alpha chain 0.0824 0.4046 0.75
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0041 0.0095
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0222 0.1048 0.7729
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0052 0.0097
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0027 0.0076 0.0142
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0021 0.0049 0.0091
Echinococcus multilocularis geminin 0.0175 0.0816 0.1515
Trichomonas vaginalis cation-transporting ATPase, putative 0.0041 0.0145 0.0218
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0024 0.0045
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0057 0.0226 0.0376
Echinococcus granulosus GA binding protein alpha chain 0.0075 0.0316 0.0587
Schistosoma mansoni tubulin subunit beta 0.1093 0.5387 1
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0041 0.0076
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0032 0.0102 0.0136
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0021 0.0045 0.0039
Leishmania major P-type H -ATPase, putative 0.0079 0.0336 0.0582
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0041 0.0145 0.0225
Brugia malayi hypothetical protein 0.0124 0.0562 0.1003
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0111 0.0161
Plasmodium falciparum glutathione reductase 0.0097 0.0427 0.0751
Brugia malayi E1-E2 ATPase family protein 0.0017 0.0029 0.0008
Toxoplasma gondii E1-E2 ATPase subfamily protein 0.007 0.0293 0.05
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0063 0.0065
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0041 0.0057
Echinococcus granulosus ecdysone induced protein 78C 0.0057 0.0226 0.0419
Onchocerca volvulus 0.0037 0.0128 0.0389
Echinococcus multilocularis Na+:K+ ATPase alpha subunit 0.0032 0.0102 0.0189
Loa Loa (eye worm) hypothetical protein 0.0027 0.0076 0.0097
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.0127
Brugia malayi hypothetical protein 0.0019 0.0038 0.0025
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0057 0.0226 0.0419
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0035 0.0046
Echinococcus multilocularis cation transporting ATPase 13A3 0.0017 0.0029 0.0053
Loa Loa (eye worm) hypothetical protein 0.0041 0.0145 0.0225
Schistosoma mansoni hypothetical protein 0.005 0.0191 0.0355
Onchocerca volvulus 0.0057 0.0226 0.0806
Trichomonas vaginalis interferon-induced GTP-binding protein mx, putative 0.0046 0.017 0.0263
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0049 0.0047
Schistosoma mansoni hypothetical protein 0.0102 0.0452 0.0839
Plasmodium falciparum tubulin delta chain, putative 0.0282 0.1347 0.2467
Echinococcus granulosus tubulin alpha 0.0615 0.3005 0.5579
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0122 0.0226
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0473 0.23 0.427
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0027 0.0077 0.0144
Giardia lamblia Delta tubulin 0.0282 0.1347 0.2461
Schistosoma mansoni tubulin subunit alpha 0.0824 0.4046 0.7511
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.017 0.0316
Echinococcus multilocularis tubulin alpha chain 0.0824 0.4046 0.7511
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0041 0.0145 0.0121
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0041 0.0057
Echinococcus multilocularis dna polymerase eta 0.002 0.0041 0.0076
Echinococcus granulosus tubulin alpha 3 chain 0.0824 0.4046 0.7511
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0196 0.0312
Brugia malayi nuclear hormone receptor 0.0027 0.0076 0.0097
Brugia malayi beta-lactamase family protein 0.0037 0.0128 0.0194
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0041 0.0057
Loa Loa (eye worm) thioredoxin reductase 0.0097 0.0427 0.0751
Schistosoma mansoni copper ABC transporter ATPase 0.0017 0.0029 0.0053
Loa Loa (eye worm) hypothetical protein 0.0057 0.0226 0.0376
Trichomonas vaginalis tubulin gamma chain, putative 0.0672 0.329 0.6087
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0057 0.0226 0.0419
Mycobacterium tuberculosis Cell division protein FtsZ 0.0282 0.1347 1
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0041 0.0095
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0196 0.0364
Leishmania major alpha tubulin 0.0824 0.4046 0.75
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0111 0.0087
Echinococcus granulosus histone lysine methyltransferase setb 0.0062 0.0252 0.0467
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0128 0.0186
Echinococcus multilocularis dna polymerase kappa 0.002 0.0041 0.0076
Schistosoma mansoni nuclear receptor 0.0027 0.0076 0.0142
Loa Loa (eye worm) hypothetical protein 0.0027 0.0076 0.0097
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0032 0.0102 0.0189
Brugia malayi Nuclear hormone receptor E75 0.0027 0.0076 0.0097
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0017 0.0029 0.0032
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0041 0.0017
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0019 0.004 0.0085
Brugia malayi Tubulin alpha chain 0.0282 0.1347 0.2467
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0027 0.0076 0.0142
Echinococcus granulosus tubulin subunit beta 0.1093 0.5387 1
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0041 0.0145 0.0225
Plasmodium vivax copper-transporting ATPase, putative 0.0017 0.0029 0.0008
Echinococcus multilocularis dnaJ subfamily B 0.0418 0.2024 0.3758
Brugia malayi Tubulin beta chain 0.0333 0.1601 0.2941
Loa Loa (eye worm) RecQ helicase 0.0044 0.0161 0.0256
Plasmodium vivax SET domain protein, putative 0.0062 0.0252 0.0424
Onchocerca volvulus 0.0062 0.0252 0.0917
Mycobacterium tuberculosis Probable cation transporter P-type ATPase D CtpD 0.0017 0.0029 0.0032
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0252 0.0467
Brugia malayi tubulin alpha-2 chain 0.0824 0.4046 0.75
Echinococcus granulosus thioredoxin glutathione reductase 0.0097 0.0427 0.0793
Echinococcus granulosus copper transporting ATPase 1 0.0017 0.0029 0.0053
Mycobacterium ulcerans hydrolase/amidase 0.0282 0.1347 1
Brugia malayi Nuclear hormone receptor-like 1 0.0057 0.0226 0.0376
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0034 0.0111 0.0205
Toxoplasma gondii heavy metal translocating P-type ATPase subfamily protein 0.0017 0.0029 0.0008
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0473 0.23 0.4244
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.0178 0.0331
Loa Loa (eye worm) nuclear receptor NHR-67 0.0027 0.0076 0.0097
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0034 0.0111 0.0161
Leishmania major zeta tubulin, putative 0.0872 0.4283 0.7942
Mycobacterium ulcerans cell division protein FtsZ 0.0282 0.1347 0.9997
Trichomonas vaginalis tubulin, putative 0.0339 0.1631 0.2992
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0041 0.0057
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0057 0.0226 0.0419
Schistosoma mansoni alpha tubulin 0.0824 0.4046 0.7511
Plasmodium vivax glutathione reductase, putative 0.0097 0.0427 0.0751
Echinococcus multilocularis tubulin alpha 1C chain 0.0824 0.4046 0.7511
Echinococcus multilocularis Tubulin beta 2C chain 0.1093 0.5387 1
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0057 0.0226 0.0419
Brugia malayi Calcitonin receptor-like protein seb-1 0.0149 0.0687 0.1236
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.0178 0.0287
Trypanosoma brucei P-type H+-ATPase, putative 0.0079 0.0336 0.0606
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0017 0.0029 0.0032
Echinococcus granulosus bloom syndrome protein 0.0044 0.0161 0.03
Loa Loa (eye worm) alpha-tubulin 0.0824 0.4046 0.75
Entamoeba histolytica Ran family GTPase 0.0022 0.0052 0.0076
Echinococcus multilocularis cation transporting atpase worm 0.0017 0.0029 0.0053
Echinococcus granulosus tubulin subunit TubB 0.0824 0.4046 0.7511
Schistosoma mansoni dynamin 0.0049 0.0187 0.0348
Schistosoma mansoni lipoxygenase 0.0114 0.051 0.0947
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0078 0.0333 0.0575
Giardia lamblia DINP protein human, muc B family 0.002 0.0041 0.0023
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0078 0.0333 0.2333
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.017 0.0272
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0078 0.0333 0.0575
Echinococcus granulosus Tubulin alpha 1 chain 0.0824 0.4046 0.7511
Trypanosoma cruzi tubulin gamma chain 0.0672 0.329 0.3274
Toxoplasma gondii P-type ATPase PMA1 0.0079 0.0336 0.0582
Echinococcus multilocularis cpg binding protein 0.0031 0.0097 0.0181
Echinococcus multilocularis Tubulin beta 2C chain 0.1093 0.5387 1
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0055 0.0219 0.0363
Trichomonas vaginalis tubulin epsilon chain, putative 0.0824 0.4046 0.7498
Trypanosoma brucei dynamin-1-like protein 0.0046 0.017 0.0296
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0149 0.0687 0.1236
Chlamydia trachomatis protoporphyrinogen oxidase 0.0021 0.0049 0.068
Loa Loa (eye worm) hypothetical protein 0.0052 0.0201 0.033
Brugia malayi nuclear receptor NHR-67 0.0027 0.0076 0.0097
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0237 0.0441
Schistosoma mansoni carbonic anhydrase-related 0.0369 0.1781 0.3307
Brugia malayi beta-tubulin, identical 0.1093 0.5387 1
Trichomonas vaginalis tubulin, putative 0.0333 0.1601 0.2935
Plasmodium vivax dynamin-like protein, putative 0.0046 0.017 0.0271
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0128 0.0757
Loa Loa (eye worm) hypothetical protein 0.003 0.0091 0.0125
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0057 0.0226 0.0419
Echinococcus multilocularis tubulin beta 1 chain 0.1093 0.5387 1
Schistosoma mansoni hypothetical protein 0.0036 0.0122 0.0226
Schistosoma mansoni hypothetical protein 0.0175 0.0816 0.1515
Trichomonas vaginalis glutathione reductase, putative 0.0034 0.0111 0.0153
Echinococcus granulosus Ca2 transporting ATPase plasma membrane 0.0032 0.0102 0.0189
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0034 0.0111 0.0653
Echinococcus multilocularis tubulin gamma 1 chain 0.0672 0.329 0.6107
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.006 0.0035
Entamoeba histolytica hypothetical protein 0.0036 0.0122 0.0205
Leishmania major beta tubulin 0.1093 0.5387 1
Mycobacterium ulcerans epimerase 0.0021 0.0045 0.0128
Loa Loa (eye worm) beta-lactamase 0.0037 0.0128 0.0194
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0041 0.0057
Plasmodium vivax tubulin alpha chain, putative 0.0824 0.4046 0.75
Leishmania major DNA polymerase eta, putative 0.002 0.0041 0.0031
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0027 0.0076 0.0097
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0128 0.0787
Loa Loa (eye worm) hypothetical protein 0.0057 0.0226 0.0376
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0041 0.0057
Leishmania major alpha tubulin 0.0824 0.4046 0.75
Brugia malayi CXXC zinc finger family protein 0.0029 0.0089 0.0121
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0018 0.0033 0.0061
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0041 0.0023
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0041 0.0145 0.0218
Trichomonas vaginalis tubulin epsilon chain, putative 0.1093 0.5387 1
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0191 0.0312
Loa Loa (eye worm) hypothetical protein 0.0027 0.0076 0.0097
Trypanosoma cruzi P-type H+-ATPase, putative 0.0079 0.0336 0.0313
Echinococcus multilocularis snurportin 1 0.0319 0.153 0.284
Mycobacterium leprae conserved hypothetical protein 0.0021 0.0045 0.0128
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0041 0.0145 0.025
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0032 0.0102 0.0078
Echinococcus granulosus lamin dm0 0.0055 0.0219 0.0407
Onchocerca volvulus 0.0027 0.0076 0.0165
Loa Loa (eye worm) hypothetical protein 0.0542 0.2642 0.4881
Schistosoma mansoni hypothetical protein 0.0418 0.2024 0.3758
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0018 0.0033 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.0282 0.1347 0.2461
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.017 0.0272
Echinococcus granulosus tubulin epsilon chain 0.0671 0.3286 0.61
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0033 0.0016
Plasmodium vivax calcium-transporting ATPase, putative 0.0041 0.0145 0.0225
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0097 0.0427 0.3046
Onchocerca volvulus 0.005 0.0191 0.0659
Brugia malayi amine oxidase, flavin-containing family protein 0.0021 0.0049 0.0047
Schistosoma mansoni hypothetical protein 0.0047 0.0178 0.0331
Leishmania major beta tubulin 0.1093 0.5387 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0057 0.0226 0.0376
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0244 0.1158 0.2114
Brugia malayi calcium ATPase 0.0032 0.0102 0.0144
Loa Loa (eye worm) hypothetical protein 0.0032 0.0102 0.0144
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0027 0.0076 0.0142
Mycobacterium ulcerans beta-lactamase 0.0037 0.0128 0.0757
Echinococcus multilocularis nuclear receptor nhr 48 0.0027 0.0076 0.0142
Loa Loa (eye worm) hypothetical protein 0.0491 0.2388 0.4407
Trypanosoma brucei carbonic anhydrase-like protein 0.0473 0.23 0.4258
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0019 0.004 0.0366
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0059 0.0109
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0122 0.0226
Schistosoma mansoni tubulin subunit beta 0.1093 0.5387 1
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0021 0.0049 0.0157
Plasmodium falciparum alpha tubulin 2 0.0824 0.4046 0.75
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0052 0.0044
Plasmodium vivax tubulin beta chain, putative 0.1093 0.5387 1
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0041 0.0057
Brugia malayi latrophilin 2 splice variant baaae 0.0102 0.0452 0.0797
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0128 0.0787
Brugia malayi Ets-domain containing protein 0.0075 0.0316 0.0544
Mycobacterium ulcerans oxidoreductase 0.0021 0.0049 0.0157
Leishmania major beta tubulin 0.1093 0.5387 1
Onchocerca volvulus 0.0037 0.0128 0.0389
Loa Loa (eye worm) hypothetical protein 0.003 0.0092 0.0127
Loa Loa (eye worm) hypothetical protein 0.0027 0.0076 0.0097
Loa Loa (eye worm) hypothetical protein 0.0324 0.1557 0.2859
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0057 0.0226 0.0376
Schistosoma mansoni nuclear hormone receptor 0.0057 0.0226 0.0419
Trypanosoma brucei beta tubulin 0.1093 0.5387 1
Leishmania major delta tubulin, putative 0.0635 0.3103 0.5742
Echinococcus multilocularis copper transporting ATPase 1 0.0017 0.0029 0.0053
Schistosoma mansoni nuclear hormone receptor 0.0027 0.0076 0.0142
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0041 0.0145 0.0218
Echinococcus granulosus carbonic anhydrase 0.0369 0.1781 0.3307
Trichomonas vaginalis tubulin alpha chain, putative 0.1093 0.5387 1
Echinococcus multilocularis carbonic anhydrase II 0.0473 0.23 0.427
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0034 0.0111 0.0161
Mycobacterium tuberculosis Probable dehydrogenase 0.0222 0.1048 0.7737
Trypanosoma brucei calcium-translocating P-type ATPase 0.0032 0.0102 0.0169
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.017 0.0316
Plasmodium falciparum tubulin gamma chain 0.0672 0.329 0.609
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0196 0.0172
Loa Loa (eye worm) hypothetical protein 0.0027 0.0076 0.0097
Echinococcus granulosus tubulin alpha chain 0.0824 0.4046 0.7511
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0041 0.0145 0.0218
Plasmodium falciparum thioredoxin reductase 0.0034 0.0111 0.0161
Trypanosoma brucei beta tubulin 0.0615 0.3005 0.5571
Leishmania major alpha tubulin 0.0824 0.4046 0.75
Entamoeba histolytica hypothetical protein 0.0036 0.0122 0.0205
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.006 0.0066

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 3.1 uM In vitro anticellular activity against HeLa S3 cells ChEMBL. 8021919
IC50 (functional) = 3.1 uM In vitro anticellular activity against HeLa S3 cells ChEMBL. 8021919
OD (functional) = 20 mg kg-1 Optimal dose of the compound against sarcoma 180 tumor in ddY mice ChEMBL. 8021919
OD (functional) = 20 mg kg-1 Optimal dose of the compound against sarcoma 180 tumor in ddY mice ChEMBL. 8021919
T/C (functional) = 0.79 min Treated versus control value of tumor volume was measured in ddY mice ChEMBL. 8021919
T/C (functional) = 0.79 min Treated versus control value of tumor volume was measured in ddY mice ChEMBL. 8021919

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 8021919

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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