Detailed information for compound 802715

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 480.551 | Formula: C26H25FN2O4S
  • H donors: 1 H acceptors: 3 LogP: 3.25 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOCCCNC(=O)c1ccc2c(c1)N(Cc1ccc(cc1)F)C(=O)c1c(S2=O)cccc1
  • InChi: 1S/C26H25FN2O4S/c1-2-33-15-5-14-28-25(30)19-10-13-24-22(16-19)29(17-18-8-11-20(27)12-9-18)26(31)21-6-3-4-7-23(21)34(24)32/h3-4,6-13,16H,2,5,14-15,17H2,1H3,(H,28,30)
  • InChiKey: AEKFHCNQFYPKKP-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0439 0.1506 0.1506
Brugia malayi intermediate filament protein 0.0026 0.0024 0.007
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0044 0.0088 0.0194
Brugia malayi AMP-binding enzyme family protein 0.0995 0.3505 1
Mycobacterium tuberculosis Probable esterase LipL 0.0439 0.1506 0.1506
Echinococcus granulosus cpg binding protein 0.0152 0.0476 0.0653
Plasmodium falciparum lysine--tRNA ligase 0.0023 0.0013 0.0082
Leishmania major dihydrolipoamide dehydrogenase, putative 0.003 0.0039 0.012
Schistosoma mansoni hypothetical protein 0.0128 0.0391 0.0537
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0137 0.091
Brugia malayi orphan nuclear receptor NR2E1 0.0044 0.0088 0.0251
Trypanosoma cruzi pyruvate kinase 2, putative 0.0035 0.0055 0.0168
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0055 0.0128 0.0128
Leishmania major glycosyl hydrolase-like protein 0.0027 0.0028 0.0087
Trypanosoma brucei unspecified product 0.0058 0.0137 0.091
Brugia malayi AMP-binding enzyme family protein 0.0087 0.0241 0.0688
Loa Loa (eye worm) hypothetical protein 0.0093 0.0265 0.0586
Loa Loa (eye worm) hypothetical protein 0.0439 0.1506 0.3342
Schistosoma mansoni nocturnin 0.002 0.0001 0.0001
Echinococcus multilocularis RUN 0.0041 0.0079 0.0107
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.003 0.0039 0.0075
Plasmodium falciparum proline--tRNA ligase 0.0036 0.006 0.0393
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0044 0.0088 0.012
Onchocerca volvulus 0.0087 0.0241 0.1597
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0093 0.0265 0.0362
Trichomonas vaginalis glutaminase, putative 0.0278 0.0929 0.5573
Trypanosoma cruzi fatty acid transporter protein-like, putative 0.0921 0.3237 1
Brugia malayi nuclear receptor RXR 0.0044 0.0088 0.0251
Giardia lamblia Kinase, CMGC MAPK 0.0108 0.0317 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0087 0.0241 0.0753
Echinococcus granulosus lysosomal alpha glucosidase 0.033 0.1116 0.1531
Echinococcus multilocularis serine protein kinase ATM 0.0026 0.0024 0.0032
Mycobacterium ulcerans acyl-CoA synthetase 0.0087 0.0241 0.0653
Loa Loa (eye worm) hypothetical protein 0.0049 0.0107 0.0236
Echinococcus granulosus acetylcholinesterase 0.0072 0.0187 0.0256
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0027 0.0028 0.0184
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0237 0.078 0.2226
Mycobacterium leprae conserved hypothetical protein 0.0439 0.1506 0.4716
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0049 0.0107 0.0146
Brugia malayi Probable ClpP-like protease 0.0084 0.0232 0.0662
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0086 0.024 0.1591
Loa Loa (eye worm) MH2 domain-containing protein 0.0351 0.119 0.2639
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0024 0.0053
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0101 0.0294 0.0403
Schistosoma mansoni pyruvate kinase 0.0035 0.0055 0.0076
Plasmodium falciparum pyruvate kinase 0.0035 0.0055 0.0362
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0036 0.006 0.0397
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0093 0.0265 0.0362
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0084 0.0232 0.0318
Schistosoma mansoni importin beta-1 0.0119 0.0359 0.0493
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.1274 0.4506 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0087 0.0241 0.0653
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.092 0.5521
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0049 0.0107 0.0147
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0128 0.0391 0.0536
Schistosoma mansoni nuclear hormone receptor 0.0044 0.0088 0.0121
Entamoeba histolytica protein kinase, putative 0.0033 0.0048 0.0269
Schistosoma mansoni FFA transport protein 0.0921 0.3237 0.4442
Loa Loa (eye worm) beta-lactamase 0.0439 0.1506 0.3342
Brugia malayi jmjC domain containing protein 0.008 0.0218 0.0622
Brugia malayi hypothetical protein 0.0049 0.0107 0.0305
Brugia malayi PHD-finger family protein 0.0059 0.0144 0.0409
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.0047 0.0281
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0406 0.1387 0.3078
Echinococcus multilocularis cpg binding protein 0.0152 0.0476 0.0653
Loa Loa (eye worm) Smad1 0.0024 0.0016 0.0034
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0097 0.0279 0.0381
Echinococcus multilocularis solute carrier family 5 0.0075 0.02 0.0273
Brugia malayi beta-lactamase 0.0439 0.1506 0.4298
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0022 0.001 0.0029
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0033 0.0048 0.0321
Toxoplasma gondii propionate-CoA ligase 0.0087 0.0241 0.16
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0026 0.0023 0.0153
Loa Loa (eye worm) hypothetical protein 0.0439 0.1506 0.3342
Plasmodium vivax importin-beta 2, putative 0.0119 0.0359 0.2379
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0093 0.0265 0.0755
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0087 0.0241 0.0241
Echinococcus granulosus solute carrier family 5 0.0075 0.02 0.0273
Toxoplasma gondii protein kinase, putative 0.0292 0.0981 0.651
Trypanosoma brucei polo-like protein kinase 0.0101 0.0294 0.1954
Loa Loa (eye worm) hypothetical protein 0.0439 0.1506 0.3342
Trypanosoma brucei glucose transporter 1E 0.0032 0.0045 0.0299
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.0047 0.0281
Trypanosoma cruzi DNA polymerase kappa, putative 0.0058 0.0137 0.0422
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.002 0.0003 0.0013
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.002 0.0001 0.0004
Giardia lamblia DINP protein human, muc B family 0.0058 0.0137 0.432
Leishmania major glucose transporter, lmgt1 0.0032 0.0045 0.0139
Schistosoma mansoni jumonji/arid domain-containing protein 0.008 0.0218 0.0299
Brugia malayi Glycosyl hydrolases family 2, sugar binding domain containing protein 0.0461 0.1586 0.4526
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.002 0.0001 0.0002
Onchocerca volvulus 0.0049 0.0107 0.0706
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0073 0.0193 0.1157
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0087 0.0241 0.16
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.003 0.0039 0.0255
Schistosoma mansoni nuclear hormone receptor 0.0093 0.0265 0.0363
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0044 0.0088 0.058
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0048 0.0065
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0199 0.0646 0.0645
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0058 0.0137 0.0187
Plasmodium falciparum calcium-dependent protein kinase 5 0.0033 0.0048 0.0317
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0044 0.0088 0.012
Mycobacterium ulcerans hypothetical protein 0.0087 0.0241 0.0653
Trypanosoma cruzi hypothetical protein, conserved 0.0439 0.1506 0.4653
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0075 0.02 0.0273
Trypanosoma cruzi DNA polymerase kappa, putative 0.0058 0.0137 0.0422
Plasmodium vivax glutathione reductase, putative 0.0087 0.0244 0.1616
Trichomonas vaginalis penicillin-binding protein, putative 0.0439 0.1506 0.9038
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.031 0.1043 0.3219
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.003 0.0039 0.0111
Loa Loa (eye worm) glycosyl hydrolase family 2 0.0461 0.1586 0.352
Echinococcus granulosus smad 0.0024 0.0016 0.0021
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0084 0.0232 0.806
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0087 0.0241 0.0653
Schistosoma mansoni hypothetical protein 0.0034 0.0053 0.0073
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0087 0.0241 0.033
Trichomonas vaginalis alpha-glucosidase, putative 0.0073 0.0193 0.1157
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0013 0.0018
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0027
Echinococcus multilocularis carboxylesterase 5A 0.0072 0.0187 0.0256
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0023
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0066 0.0167 0.0477
Loa Loa (eye worm) hypothetical protein 0.0044 0.0088 0.0194
Brugia malayi Isocitrate dehydrogenase 0.0033 0.0049 0.014
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0024 0.0016 0.0022
Plasmodium vivax multidomain scavenger receptor, putative 0.0041 0.0079 0.052
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0087 0.0241 0.0688
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.003 0.0039 0.0255
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.03 0.0412
Echinococcus granulosus high affinity choline transporter 1 0.0075 0.02 0.0273
Loa Loa (eye worm) glutaminase 0.0278 0.0929 0.2061
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0049 0.0107 0.0146
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0024 0.0016 0.0021
Schistosoma mansoni nuclear hormone receptor 0.0044 0.0088 0.0121
Brugia malayi Pre-SET motif family protein 0.021 0.0685 0.1954
Plasmodium vivax transportin, putative 0.0023 0.0011 0.0071
Schistosoma mansoni hypothetical protein 0.0103 0.03 0.0412
Schistosoma mansoni acetyl-CoA synthetase 0.0087 0.0241 0.0331
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0176 0.0564 0.1578
Onchocerca volvulus 0.0026 0.0024 0.0158
Echinococcus multilocularis survival motor neuron protein 1 0.0241 0.0796 0.1092
Echinococcus multilocularis musashi 0.0026 0.0024 0.0033
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0087 0.0241 0.0241
Echinococcus granulosus jumonji domain containing protein 0.0083 0.0227 0.0311
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0084 0.0232 0.1537
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0024 0.014
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0033 0.0049 0.0325
Loa Loa (eye worm) steroid hormone receptor 0.0093 0.0265 0.0586
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0028 0.0166
Plasmodium vivax SET domain protein, putative 0.0033 0.0048 0.0316
Echinococcus granulosus mothers against decapentaplegic 5 0.0024 0.0016 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0045 0.0267
Trichomonas vaginalis conserved hypothetical protein 0.0103 0.03 0.18
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0087 0.0266
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0151 0.0335
Loa Loa (eye worm) hypothetical protein 0.0087 0.0241 0.0534
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0176 0.0564 0.0563
Toxoplasma gondii LsmAD domain-containing protein 0.0076 0.0204 0.1354
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0087 0.0241 0.0241
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0087 0.0241 0.0653
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0087 0.0241 0.16
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0103 0.0142
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0093 0.0265 0.0755
Trypanosoma brucei glucose transporter, putative 0.0032 0.0045 0.0299
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0022 0.0011 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0047 0.0281
Brugia malayi hypothetical protein 0.0041 0.0079 0.0225
Brugia malayi acetyltransferase, GNAT family protein 0.0293 0.0982 0.2802
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0046 0.0094 0.0128
Loa Loa (eye worm) importin-beta domain-containing protein 0.0023 0.0011 0.0024
Schistosoma mansoni transcription factor LCR-F1 0.0512 0.1768 0.2426
Brugia malayi MH2 domain containing protein 0.0024 0.0016 0.0046
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0041 0.0057
Trypanosoma brucei hypothetical protein, conserved 0.0439 0.1506 1
Trypanosoma cruzi trypanothione reductase, putative 0.003 0.0039 0.0119
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0041 0.0057
Onchocerca volvulus 0.0075 0.02 0.1322
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0093 0.0265 0.0363
Leishmania major 4-coumarate:coa ligase-like protein 0.0087 0.0241 0.0753
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0237 0.078 0.1071
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0093 0.0265 0.0755
Schistosoma mansoni serine/threonine protein kinase 0.0108 0.0317 0.0434
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0026 0.0024 0.0072
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.003 0.0039 0.0255
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0237 0.078 0.1071
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0048 0.0065
Echinococcus multilocularis translational activator gcn1 0.0023 0.0011 0.0015
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0097 0.0279 0.0859
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0084 0.0232 0.1538
Onchocerca volvulus 0.0048 0.0103 0.0682
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.002 0.0001 0.0004
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0028 0.0166
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0093 0.0265 0.0586
Leishmania major pyruvate kinase 0.0035 0.0055 0.0171
Giardia lamblia Lysyl-tRNA synthetase 0.0023 0.0013 0.039
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0044 0.0087 0.0576
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0093 0.0265 0.0363
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0151 0.0208
Schistosoma mansoni hypothetical protein 0.139 0.4923 0.6756
Giardia lamblia NADH oxidase lateral transfer candidate 0.003 0.0039 0.1215
Schistosoma mansoni ran 0.0066 0.0167 0.0229
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.002 0.0001 0.0004
Brugia malayi nuclear receptor NHR-67 0.0044 0.0088 0.0251
Schistosoma mansoni synaptojanin 0.002 0.0001 0.0001
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.002 0.0001 0.0004
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0294 0.1763
Loa Loa (eye worm) nuclear hormone receptor 0.0044 0.0088 0.0194
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.003 0.0039 0.0119
Trypanosoma brucei DNA polymerase IV, putative 0.0058 0.0137 0.091
Loa Loa (eye worm) RNA binding protein 0.0062 0.0151 0.0335
Onchocerca volvulus 0.0041 0.0079 0.052
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0294 0.1763
Entamoeba histolytica acetyltransferase, GNAT family 0.0079 0.0214 0.1206
Schistosoma mansoni glucose transport protein 0.0103 0.03 0.0412
Entamoeba histolytica acyl-CoA synthetase, putative 0.0087 0.0241 0.136
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0049 0.0152
Treponema pallidum NADH oxidase 0.003 0.0039 0.1382
Plasmodium falciparum calcium-dependent protein kinase 1 0.0033 0.0048 0.0317
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0066 0.0167 0.0514
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.002 0.0001 0.0004
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0165 0.0521 0.1156
Schistosoma mansoni alpha-glucosidase 0.0284 0.0951 0.1305
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0033 0.0048 0.0138
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0039 0.0119
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0093 0.0265 0.0586
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0512 0.1768 0.2426
Echinococcus multilocularis pyruvate kinase 0.0035 0.0055 0.0075
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0049 0.0325
Plasmodium falciparum phd finger protein, putative 0.0059 0.0144 0.0949
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0033 0.0048 0.0065
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.002 0.0001 0.0001
Loa Loa (eye worm) glutaminase 2 0.0278 0.0929 0.2061
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0168 0.0533 0.3536
Echinococcus granulosus pyruvate kinase 0.0035 0.0055 0.0075
Loa Loa (eye worm) hypothetical protein 0.0026 0.0024 0.0053
Trypanosoma cruzi hexose transporter 0.0032 0.0045 0.0137
Schistosoma mansoni hypothetical protein 0.0041 0.0079 0.0108
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0055 0.0362
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0137 0.091
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0093 0.0265 0.0586
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0045 0.0267
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0058 0.0137 0.0188
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0176 0.0564 0.1578
Loa Loa (eye worm) CXXC zinc finger family protein 0.0144 0.0447 0.0991
Loa Loa (eye worm) hypothetical protein 0.0026 0.0023 0.0049
Plasmodium falciparum protein kinase 7 0.0292 0.0981 0.6511
Mycobacterium ulcerans acyl-CoA synthetase 0.0087 0.0241 0.0653
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.003 0.0039 0.012
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0093 0.0265 0.0755
Echinococcus granulosus ecdysone induced protein 78C 0.0093 0.0265 0.0362
Leishmania major acetoin dehydrogenase e3 component-like protein 0.003 0.0039 0.012
Schistosoma mansoni hypothetical protein 0.002 0.0001 0.0001
Schistosoma mansoni retinoic acid receptor RXR 0.0093 0.0265 0.0363
Trypanosoma brucei trypanothione reductase 0.0087 0.0244 0.162
Entamoeba histolytica HEAT repeat domain containing protein 0.0023 0.0011 0.0061
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0045 0.0137
Schistosoma mansoni smad1 5 8 and 0.0024 0.0016 0.0022
Schistosoma mansoni DNA polymerase eta 0.0058 0.0137 0.0188
Schistosoma mansoni pyruvate kinase 0.0035 0.0055 0.0076
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0439 0.1506 0.4298
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0101 0.0294 0.0403
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0048 0.032
Trypanosoma brucei pyruvate kinase 1, putative 0.0035 0.0055 0.0366
Brugia malayi MH1 domain containing protein 0.0024 0.0016 0.0046
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.002 0.0001 0.0004
Plasmodium vivax lysine--tRNA ligase, putative 0.0023 0.0013 0.0082
Schistosoma mansoni carbon catabolite repressor protein 0.002 0.0001 0.0001
Brugia malayi manba-prov protein 0.0157 0.0493 0.1408
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0137 0.091
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0087 0.0241 0.0241
Onchocerca volvulus 0.0026 0.0024 0.0158
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0075 0.02 0.0273
Echinococcus multilocularis jumonji domain containing protein 0.0083 0.0227 0.0311
Schistosoma mansoni hypothetical protein 0.139 0.4923 0.6756
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0073 0.0484
Brugia malayi ImpB/MucB/SamB family protein 0.0058 0.0137 0.0391
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.002 0.0001 0.0004
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0058 0.0137 0.0303
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.058 0.3477
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0293 0.0982 0.1348
Echinococcus multilocularis neuropeptide s receptor 0.0473 0.1629 0.2235
Toxoplasma gondii PHD-finger domain-containing protein 0.0059 0.0144 0.0953
Toxoplasma gondii facilitative glucose transporter GT1 0.0103 0.03 0.1995
Brugia malayi Thioredoxin reductase 0.0087 0.0244 0.0696
Leishmania major fatty acid transporter protein-like protein 0.0909 0.3194 1
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.058 0.3477
Toxoplasma gondii ABC1 family protein 0.0439 0.1506 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0137 0.091
Mycobacterium tuberculosis Probable lipase LipD 0.0439 0.1506 0.1506
Leishmania major importin beta-1 subunit, putative 0.0097 0.0278 0.0868
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0151 0.0208
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0097 0.0279 1
Trypanosoma brucei unspecified product 0.004 0.0073 0.0484
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0033 0.0048 0.0317
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0066 0.0167 0.0514
Echinococcus multilocularis beta LACTamase domain containing family member 0.0439 0.1506 0.2066
Leishmania major protein kinase, putative 0.0033 0.0048 0.0149
Loa Loa (eye worm) hypothetical protein 0.0044 0.0088 0.0194
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0199 0.0646 0.0645
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0023 0.0013 0.0039
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0087 0.0241 0.16
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0028 0.0166
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0097 0.0279 0.1846
Brugia malayi nuclear hormone receptor family member nhr-6 0.0044 0.0088 0.0251
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.0615 0.3687
Echinococcus multilocularis lysyl tRNA synthetase 0.0023 0.0013 0.0017
Brugia malayi ecdysone receptor 0.0044 0.0088 0.0251
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0073 0.0484
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0033 0.0048 0.0066
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0103 0.03 0.0412
Mycobacterium leprae possible long-chain acyl-CoA synthase 0.0909 0.3194 1
Entamoeba histolytica beta-galactosidase, putative 0.0327 0.1104 0.624
Echinococcus multilocularis lamin 0.0026 0.0024 0.0033
Trichomonas vaginalis CAMK family protein kinase 0.0033 0.0048 0.0286
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0037 0.0063 0.0085
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.03 0.0412
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0048 0.0065
Echinococcus multilocularis tumor protein p63 0.0329 0.1112 0.1526
Leishmania major acetyl-CoA synthetase, putative 0.0087 0.0241 0.0753
Schistosoma mansoni cpg binding protein 0.0152 0.0476 0.0654
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0023 0.0013 0.0086
Trypanosoma brucei DNA polymerase IV, putative 0.0058 0.0137 0.091
Leishmania major DNA polymerase eta, putative 0.0058 0.0137 0.0427
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0108 0.0317 0.0989
Echinococcus granulosus transportin 1 0.0023 0.0011 0.0015
Mycobacterium ulcerans acyl-CoA synthetase 0.0087 0.0241 0.0653
Trypanosoma brucei RNA editing exonuclease 2 0.002 0.0001 0.0004
Plasmodium falciparum hexose transporter 0.0103 0.03 0.1992
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0026 0.0024 0.0159
Brugia malayi photoreceptor-specific nuclear receptor 0.0093 0.0265 0.0755
Plasmodium falciparum calcium-dependent protein kinase 2 0.0033 0.0048 0.0317
Echinococcus granulosus sodium:glucose cotransporter 0.0075 0.02 0.0273
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0044 0.0088 0.0251
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0027 0.0029 0.0038
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.003 0.0039 0.0053
Schistosoma mansoni serine/threonine protein kinase 0.0101 0.0294 0.0404
Echinococcus granulosus lipoxygenase domain containing protein 0.0041 0.0079 0.0107
Loa Loa (eye worm) acetyltransferase 0.0293 0.0982 0.2179
Brugia malayi F/Y-rich N-terminus family protein 0.0064 0.0162 0.0461
Loa Loa (eye worm) hypothetical protein 0.0072 0.0187 0.0414
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.002 0.0001 0.0002
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0276 0.092 0.2042
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0093 0.0265 0.0362
Plasmodium vivax hypothetical protein, conserved 0.0439 0.1506 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.0088 0.0194
Schistosoma mansoni hypothetical protein 0.0277 0.0926 0.1271
Echinococcus multilocularis geminin 0.139 0.4923 0.6756
Echinococcus granulosus GPCR family 2 0.0128 0.0391 0.0536
Brugia malayi nuclear receptor NHR-88 0.0044 0.0088 0.0251
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0084 0.0232 0.0628
Schistosoma mansoni survival motor neuron protein 0.0049 0.0107 0.0147
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0049 0.0325
Schistosoma mansoni alpha glucosidase 0.0073 0.0193 0.0265
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0097 0.0279 0.8797
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0294 0.1763
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0022 0.001 0.0029
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0033 0.0049 0.0321
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.002 0.0001 0.0004
Echinococcus multilocularis acetylcholinesterase 0.0072 0.0187 0.0256
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0199 0.0646 0.0645
Trichomonas vaginalis importin beta-1, putative 0.0097 0.0278 0.1664
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0176 0.0564 0.1764
Onchocerca volvulus 0.0191 0.0616 0.4087
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0055 0.0128 0.04
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0093 0.0265 0.0363
Loa Loa (eye worm) jmjC domain-containing protein 0.0123 0.0371 0.0821
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0108 0.0317 0.0976
Trypanosoma brucei glucose transporter, putative 0.0032 0.0045 0.0299
Echinococcus multilocularis acetylcholinesterase 0.0072 0.0187 0.0256
Loa Loa (eye worm) hypothetical protein 0.0031 0.0041 0.009
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0044 0.0088 0.012
Mycobacterium tuberculosis Conserved hypothetical protein 0.0058 0.0137 0.0137
Trypanosoma brucei importin beta-1 subunit, putative 0.0119 0.0359 0.2383
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0093 0.0265 0.0362
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0093 0.0265 0.0362
Brugia malayi AMP-binding enzyme family protein 0.0087 0.0241 0.0688
Mycobacterium tuberculosis Conserved protein 0.0439 0.1506 0.1506
Chlamydia trachomatis pyruvate kinase 0.0035 0.0055 0.1926
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0047 0.0281
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.002 0.0001 0.0002
Brugia malayi ImpB/MucB/SamB family protein 0.0058 0.0137 0.0391
Loa Loa (eye worm) hypothetical protein 0.0049 0.0107 0.0236
Onchocerca volvulus 0.0239 0.0787 0.5225
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0097 0.0279 0.1572
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0093 0.0265 0.0586
Toxoplasma gondii exonuclease III APE 0.0097 0.0279 0.1849
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0151 0.0432
Loa Loa (eye worm) acetylcholinesterase 1 0.0072 0.0187 0.0414
Echinococcus granulosus geminin 0.139 0.4923 0.6756
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0033 0.0049 0.0066
Trypanosoma cruzi PAB1-binding protein , putative 0.0076 0.0204 0.0628
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0147 0.0457 0.1409
Mycobacterium ulcerans acyl-CoA synthetase 0.0087 0.0241 0.0653
Plasmodium falciparum glutathione reductase 0.003 0.0039 0.0255
Entamoeba histolytica acyl-CoA synthetase, putative 0.0087 0.0241 0.136
Schistosoma mansoni alpha-glucosidase 0.0284 0.0951 0.1305
Brugia malayi hypothetical protein 0.0041 0.0079 0.0225
Brugia malayi Glycosyl hydrolases family 31 protein 0.033 0.1116 0.3184
Leishmania major GTP-binding protein, putative 0.0066 0.0167 0.0521
Brugia malayi Nuclear hormone receptor-like 1 0.0049 0.0107 0.0305
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0176 0.0564 0.1609
Echinococcus multilocularis neuropeptide receptor A26 0.0473 0.1629 0.2235
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0044 0.0088 0.012
Brugia malayi Latrophilin receptor protein 2 0.0128 0.0391 0.1117
Onchocerca volvulus Alhambra homolog 0.0059 0.0144 0.0949
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0108 0.0317 0.0701
Loa Loa (eye worm) hypothetical protein 0.0075 0.02 0.0442
Brugia malayi Pre-SET motif family protein 0.0033 0.0048 0.0138
Brugia malayi MH2 domain containing protein 0.0024 0.0016 0.0046
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0033 0.0048 0.0321
Trichomonas vaginalis alpha-glucosidase, putative 0.0073 0.0193 0.1157
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0031 0.0205
Trypanosoma cruzi trypanothione reductase, putative 0.0087 0.0244 0.0752
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0087 0.0241 0.0241
Brugia malayi Glycosyl hydrolases family 31 protein 0.0027 0.0028 0.0081
Schistosoma mansoni thyroid hormone receptor 0.0093 0.0265 0.0363
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0032 0.0044 0.0133
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0045 0.0267
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0137 0.091
Toxoplasma gondii HEAT repeat-containing protein 0.0119 0.0359 0.2383
Trypanosoma cruzi PAB1-binding protein , putative 0.0076 0.0204 0.0628
Mycobacterium tuberculosis Probable dehydrogenase 0.0199 0.0646 0.0645
Trypanosoma brucei DNA polymerase IV, putative 0.0058 0.0137 0.091
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0087 0.0241 0.0241
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0073 0.0193 0.0428
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.003 0.0039 0.0259
Echinococcus granulosus dnaJ subfamily B 0.2048 0.7287 1
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0101 0.0294 0.092
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0087 0.0241 0.033
Brugia malayi Pyruvate kinase, M2 isozyme 0.0035 0.0055 0.0157
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0027 0.0028 0.0086
Brugia malayi ecdysteroid receptor 0.0093 0.0265 0.0755
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0087 0.0241 0.0653
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0059 0.0144 0.0197
Trichomonas vaginalis set domain proteins, putative 0.0239 0.0787 0.4722
Echinococcus granulosus Smad4 0.0024 0.0016 0.0021
Echinococcus multilocularis pyruvate kinase 0.0035 0.0055 0.0075
Schistosoma mansoni lipoxygenase 0.0041 0.0079 0.0108
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0045 0.0137
Schistosoma mansoni glutaminase 0.0278 0.0929 0.1275
Loa Loa (eye worm) hypothetical protein 0.0059 0.0144 0.0317
Echinococcus multilocularis high affinity choline transporter 1 0.0075 0.02 0.0273
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0058 0.0137 0.0427
Echinococcus multilocularis long chain fatty acid transport protein 4 0.0921 0.3237 0.4442
Loa Loa (eye worm) MH2 domain-containing protein 0.0024 0.0016 0.0034
Schistosoma mansoni rab6-interacting 0.0041 0.0079 0.0108
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0033 0.0048 0.0065
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0073 0.0484
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0093 0.0265 0.0755
Mycobacterium ulcerans acyl-CoA synthetase 0.0087 0.0241 0.0653
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0027 0.0028 0.0086
Brugia malayi exodeoxyribonuclease III family protein 0.0097 0.0279 0.0795
Schistosoma mansoni Smad4 0.0024 0.0016 0.0022
Echinococcus granulosus intermediate filament protein 0.0026 0.0024 0.0033
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0199 0.0646 0.2021
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0084 0.0232 0.1541
Mycobacterium leprae Probable pyruvate kinase PykA 0.0035 0.0055 0.0171
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.058 0.3477
Loa Loa (eye worm) hypothetical protein 0.0048 0.0103 0.0228
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.002 0.0001 0.0002
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0087 0.0241 0.0753
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0097 0.0279 0.087
Echinococcus multilocularis dna polymerase kappa 0.0058 0.0137 0.0187
Schistosoma mansoni hypothetical protein 0.0128 0.0391 0.0537
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0026 0.0024 0.0033
Echinococcus multilocularis mitogen activated protein kinase 0.0108 0.0317 0.0434
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0049 0.0325
Echinococcus multilocularis snurportin 1 0.1274 0.4506 0.6183
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0066 0.0167 0.1106
Schistosoma mansoni hypothetical protein 0.0049 0.0107 0.0147
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0037 0.0063 0.0085
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.0047 0.0281
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0097 0.0279 0.1846
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0866 0.3039 0.417
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0147 0.0457 0.1428
Loa Loa (eye worm) hypothetical protein 0.0093 0.0265 0.0586
Schistosoma mansoni kinase 0.0053 0.012 0.0165
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0084 0.0232 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0093 0.0265 0.0362
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.092 0.5521
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0039 0.0119
Leishmania major alpha glucosidase II subunit, putative 0.0073 0.0193 0.0604
Schistosoma mansoni steroid hormone receptor ad4bp 0.0093 0.0265 0.0363
Plasmodium falciparum ataxin-2 like protein, putative 0.0076 0.0204 0.1351
Echinococcus granulosus beta LACTamase domain containing family member 0.0439 0.1506 0.2066
Leishmania major DNA polymerase kappa, putative 0.0058 0.0137 0.0427
Echinococcus granulosus sodium:myo inositol cotransporter 0.0075 0.02 0.0273
Trichomonas vaginalis alpha-glucosidase, putative 0.0073 0.0193 0.1157
Trichomonas vaginalis conserved hypothetical protein 0.0483 0.1667 1
Echinococcus multilocularis transportin 1 0.0023 0.0011 0.0015
Loa Loa (eye worm) nuclear receptor NHR-67 0.0044 0.0088 0.0194
Echinococcus multilocularis lysine specific demethylase 5A 0.0072 0.0188 0.0258
Brugia malayi nuclear receptor RXR 0.0049 0.0107 0.0305
Mycobacterium ulcerans flavoprotein disulfide reductase 0.003 0.0039 0.0075
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0049 0.015
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0087 0.0241 0.0241
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0093 0.0265 0.0755
Trichomonas vaginalis ap endonuclease, putative 0.0097 0.0279 0.1668
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0024 0.007
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0087 0.0241 0.0241
Schistosoma mansoni lamin 0.0026 0.0024 0.0034
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0066 0.0167 0.527
Schistosoma mansoni sodium/solute symporter 0.0075 0.02 0.0274
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0093 0.0265 0.0755
Brugia malayi RNA binding protein 0.0062 0.0151 0.0432
Echinococcus granulosus pyruvate kinase 0.0035 0.0055 0.0075
Trichomonas vaginalis DNA polymerase eta, putative 0.0058 0.0137 0.0819
Leishmania major mitochondrial DNA polymerase beta 0.031 0.1043 0.3263
Echinococcus multilocularis mothers against decapentaplegic 5 0.0024 0.0016 0.0021
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0033 0.0048 0.0106
Loa Loa (eye worm) hypothetical protein 0.0044 0.0088 0.0194
Brugia malayi Sodium:solute symporter family protein 0.0075 0.02 0.057
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0033 0.0044
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0044 0.0088 0.0121
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0031 0.0041 0.0245
Schistosoma mansoni glucose transport protein 0.0103 0.03 0.0412
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0439 0.1506 0.1506
Trypanosoma brucei glucose transporter, putative 0.0032 0.0045 0.0299
Echinococcus multilocularis thyroid hormone receptor alpha 0.0093 0.0265 0.0362
Trypanosoma cruzi polo-like protein kinase, putative 0.0101 0.0294 0.0907
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0108 0.0317 0.0989
Entamoeba histolytica acyl-coA synthetase, putative 0.0087 0.0241 0.136
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0046 0.0094 0.0128
Schistosoma mansoni smad1 5 8 and 0.0024 0.0016 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0137 0.091
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0168 0.0533 0.3538
Echinococcus granulosus Nuclear hormone receptor HR96 0.0044 0.0088 0.012
Toxoplasma gondii hypothetical protein 0.005 0.011 0.0728
Echinococcus granulosus General substrate transporter 0.0089 0.0248 0.034
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0108 0.0317 0.2101
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0028 0.0166
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0193 0.0596
Schistosoma mansoni thyroid hormone receptor 0.0093 0.0265 0.0363
Trichomonas vaginalis alpha-glucosidase, putative 0.0073 0.0193 0.1157
Echinococcus granulosus importin 5 0.0023 0.0011 0.0015
Echinococcus granulosus importin subunit beta 1 0.0119 0.0359 0.0492
Echinococcus granulosus Nuclear hormone receptor HR96 0.0044 0.0088 0.012
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0047 0.0281
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0074 0.0198 0.0197
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0093 0.0265 0.0362
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0093 0.0265 0.0755
Echinococcus multilocularis Smad4 0.0024 0.0016 0.0021
Loa Loa (eye worm) sugar transporter 0.0103 0.03 0.0666
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0087 0.0241 0.0753
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.0023 0.0011 0.0076
Toxoplasma gondii hypothetical protein 0.0029 0.0034 0.0228
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0066 0.0167 0.037
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0045 0.0267
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0101 0.0294 0.0652
Mycobacterium ulcerans acyl-CoA synthetase 0.0087 0.0241 0.0653
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0026 0.0024 0.0068
Schistosoma mansoni hypothetical protein 0.0059 0.0144 0.0197
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0022 0.0008 0.0011
Brugia malayi Carboxylesterase family protein 0.0072 0.0187 0.0535
Entamoeba histolytica hypothetical protein 0.0026 0.0024 0.0132
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0097 0.0279 0.1849
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0033 0.0047 0.0281
Mycobacterium tuberculosis Probable oxidoreductase 0.0221 0.0726 0.0725
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0176 0.0564 0.0774
Loa Loa (eye worm) hypothetical protein 0.0044 0.0088 0.0194
Brugia malayi CCR4 0.002 0.0001 0.0002
Trypanosoma brucei glucosidase, putative 0.0073 0.0193 0.1284
Echinococcus granulosus mitogen activated protein kinase 3 0.0108 0.0317 0.0434
Treponema pallidum exodeoxyribonuclease (exoA) 0.0097 0.0279 1
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.003 0.0039 0.0259
Loa Loa (eye worm) hypothetical protein 0.0049 0.0107 0.0236
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0058 0.0137 0.0187
Echinococcus granulosus dna polymerase kappa 0.0058 0.0137 0.0187
Toxoplasma gondii HEAT repeat-containing protein 0.0023 0.0011 0.0076
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.003 0.0039 0.0255
Mycobacterium ulcerans DNA polymerase IV 0.0058 0.0137 0.0356
Trypanosoma brucei glycosyl hydrolase-like protein 0.0027 0.0028 0.0188
Leishmania major hypothetical protein, conserved 0.0076 0.0204 0.0637
Loa Loa (eye worm) hypothetical protein 0.0024 0.0017 0.0037
Brugia malayi steroid hormone receptor 0.0093 0.0265 0.0755
Schistosoma mansoni zinc finger protein 0.0044 0.0088 0.0121
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.03 0.0412
Echinococcus multilocularis peregrin 0.0067 0.0169 0.0231
Echinococcus granulosus lysine specific demethylase 5A 0.008 0.0218 0.0298
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0027 0.0028 0.0157
Leishmania major acetyl-CoA synthetase, putative 0.0087 0.0241 0.0753
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0028 0.0166
Loa Loa (eye worm) hypothetical protein 0.0075 0.02 0.0442
Echinococcus multilocularis lamin dm0 0.0026 0.0024 0.0033
Leishmania major lysyl-tRNA synthetase, putative 0.0023 0.0013 0.0039
Mycobacterium tuberculosis Probable lipase LipE 0.0439 0.1506 0.1506
Schistosoma mansoni hypothetical protein 0.0512 0.1768 0.2426
Brugia malayi Calcitonin receptor-like protein seb-1 0.0406 0.1387 0.3959
Leishmania major glucose transporter, lmgt3 0.0032 0.0045 0.0139
Plasmodium falciparum LCCL domain-containing protein 0.0041 0.0079 0.052
Toxoplasma gondii PHD-finger domain-containing protein 0.0059 0.0144 0.0953
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.003 0.0039 0.119
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0087 0.0241 0.0653
Brugia malayi Sugar transporter family protein 0.0103 0.03 0.0857
Trypanosoma brucei mitochondrial DNA polymerase beta 0.031 0.1043 0.6921
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0058 0.0137 0.0819
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0087 0.0241 0.0688
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0033 0.0048 0.032
Brugia malayi serine/threonine-protein kinase plk-2 0.0101 0.0294 0.084
Brugia malayi nuclear hormone receptor family member odr-7 0.0044 0.0088 0.0251
Brugia malayi Nuclear hormone receptor-like 1 0.0093 0.0265 0.0755
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0044 0.0087 0.0266
Echinococcus granulosus lamin dm0 0.0026 0.0024 0.0033
Trichomonas vaginalis bromodomain-containing protein, putative 0.0086 0.024 0.1435
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0151 0.0208
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0029 0.0034 0.0224
Mycobacterium ulcerans lipase LipD 0.0439 0.1506 0.4277
Schistosoma mansoni ap endonuclease 0.0097 0.0279 0.0382
Trichomonas vaginalis ran, putative 0.0066 0.0167 0.0999
Trichomonas vaginalis D-aminoacylase, putative 0.0439 0.1506 0.9038
Schistosoma mansoni smad 0.0024 0.0016 0.0022
Brugia malayi Importin beta-1 subunit 0.0119 0.0359 0.1024
Giardia lamblia Kinase, PLK 0.0101 0.0294 0.9296
Loa Loa (eye worm) hypothetical protein 0.0277 0.0926 0.2055
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0087 0.0241 0.0653
Trypanosoma cruzi DNA polymerase eta, putative 0.0058 0.0137 0.0422
Loa Loa (eye worm) kap beta 3 protein 0.0023 0.0011 0.0024
Loa Loa (eye worm) hypothetical protein 0.0072 0.0187 0.0414
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.002 0.0001 0.0004
Brugia malayi Nuclear hormone receptor E75 0.0044 0.0088 0.0251
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.002 0.0001 0.0002
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0033 0.0048 0.0317
Giardia lamblia Pyruvate kinase 0.0035 0.0055 0.1726
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0237 0.078 0.107
Plasmodium vivax CDK-related protein kinase 6, putative 0.0439 0.1506 0.9997
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0087 0.0241 0.0241
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0033 0.0049 0.0322
Schistosoma mansoni cpg binding protein 0.0152 0.0476 0.0654
Leishmania major glucose transporter/membrane transporter D2, putative 0.0032 0.0045 0.0139
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0103 0.03 0.0412
Trichomonas vaginalis beta-galactosidase, putative 0.0483 0.1667 1
Onchocerca volvulus Protein ultraspiracle homolog 0.0093 0.0265 0.1753
Leishmania major trypanothione reductase 0.0087 0.0244 0.0762
Schistosoma mansoni synaptojanin 0.002 0.0001 0.0001
Echinococcus granulosus snurportin 1 0.1274 0.4506 0.6183
Onchocerca volvulus 0.0087 0.0241 0.1597
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0406 0.1387 0.3959
Mycobacterium leprae Probable lipase LipE 0.0439 0.1506 0.4716
Mycobacterium tuberculosis Probable reductase 0.0199 0.0646 0.0645
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.002 0.0001 0.0004
Mycobacterium tuberculosis Conserved protein 0.0439 0.1506 0.1506
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0439 0.1506 0.4277
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0028 0.0031 0.0205
Trichomonas vaginalis beta-mannosidase, putative 0.0157 0.0493 0.2958
Loa Loa (eye worm) latrophilin receptor protein 2 0.0128 0.0391 0.0867
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0086 0.024 0.1591
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD6 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0909 0.3194 0.3194
Schistosoma mansoni lipoxygenase 0.0116 0.0346 0.0475
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0047 0.0281
Brugia malayi hypothetical protein 0.0044 0.0088 0.0251
Onchocerca volvulus 0.0033 0.0048 0.0316
Echinococcus multilocularis neutral alpha glucosidase AB 0.0073 0.0193 0.0265
Echinococcus multilocularis pyruvate kinase 0.0027 0.0029 0.0039
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0066 0.0167 0.1109
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0194 0.0629 0.0862
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0276 0.092 0.2626
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0029 0.0034 0.0106
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.03 0.0412
Loa Loa (eye worm) hypothetical protein 0.0031 0.0041 0.009
Brugia malayi beta-lactamase family protein 0.0439 0.1506 0.4298
Loa Loa (eye worm) hypothetical protein 0.0076 0.0204 0.0451
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0084 0.0232 0.0318
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0151 0.0207
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.002 0.0001 0.0002
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0294 0.1763
Onchocerca volvulus Glucosylceramidase homolog 0.0181 0.058 0.3847
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0087 0.0241 0.0241
Trichomonas vaginalis helicase, putative 0.0033 0.0047 0.0281
Schistosoma mansoni beta-mannosidase 0.0157 0.0493 0.0677
Schistosoma mansoni neutral sphingomyelinase 0.002 0.0001 0.0001
Echinococcus granulosus nuclear receptor nhr 48 0.0044 0.0088 0.012
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0439 0.1506 0.3342
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.021 0.0685 0.1518
Trypanosoma brucei glucose transporter, putative 0.0032 0.0045 0.0299
Brugia malayi TAR-binding protein 0.0062 0.0151 0.0432
Plasmodium falciparum ataxin-2 like protein, putative 0.0076 0.0204 0.1351
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0093 0.0265 0.0755
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0075 0.02 0.1326
Echinococcus granulosus sodium:glucose cotransporter 2 0.0075 0.02 0.0273
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0045 0.0299
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.033 0.1116 0.2476
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0045 0.0267
Brugia malayi AMP-binding enzyme family protein 0.0087 0.0241 0.0688
Brugia malayi glutathione reductase 0.0087 0.0244 0.0696
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.003 0.0039 0.0259
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0048 0.0066
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.058 0.3477
Loa Loa (eye worm) isocitrate dehydrogenase 0.0033 0.0049 0.0107
Toxoplasma gondii pyruvate kinase PyK1 0.0035 0.0055 0.0366
Entamoeba histolytica hypothetical protein 0.0512 0.1768 1
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0294 0.1763
Toxoplasma gondii thioredoxin reductase 0.0087 0.0244 0.162
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0045 0.0267
Echinococcus multilocularis calcium dependent protein kinase 0.003 0.0037 0.0049
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0116 0.0346 0.0474
Trypanosoma brucei glucose transporter 2A 0.0032 0.0045 0.0299
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0047 0.0281
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0084 0.0232 0.1541
Trichomonas vaginalis mercuric reductase, putative 0.003 0.0039 0.023
Giardia lamblia PHD finger protein 15 0.0059 0.0144 0.4523
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0128 0.0391 0.0536
Loa Loa (eye worm) transcription factor SMAD2 0.0351 0.119 0.2639
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0049 0.0066
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0093 0.0265 0.0363
Brugia malayi Nuclear hormone receptor E75 0.0044 0.0088 0.0251
Loa Loa (eye worm) hypothetical protein 0.0025 0.0021 0.0044
Schistosoma mansoni cpg binding protein 0.0144 0.0447 0.0613
Echinococcus granulosus Polycystic kidney disease protein 0.0041 0.0079 0.0107
Plasmodium falciparum thioredoxin reductase 0.003 0.0039 0.0255
Echinococcus granulosus serine protein kinase ATM 0.0026 0.0024 0.0032
Schistosoma mansoni jumonji domain containing protein 0.0154 0.0485 0.0666
Schistosoma mansoni glucose transport protein 0.0103 0.03 0.0412
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0107 0.0305
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.0047 0.0281
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0039 0.0119
Trypanosoma brucei glucose transporter, putative 0.0032 0.0045 0.0299
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0073 0.0193 0.1157
Trypanosoma cruzi hypothetical protein, conserved 0.0439 0.1506 0.4653
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0048 0.0065
Plasmodium falciparum mitogen-activated protein kinase 2 0.0168 0.0533 0.3537
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.003 0.0039 0.0053
Onchocerca volvulus 0.0439 0.1506 1
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0013 0.0018
Brugia malayi MH1 domain containing protein 0.0024 0.0016 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0047 0.0281
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0097 0.0279 0.0761
Trypanosoma brucei glucose transporter, putative 0.0032 0.0045 0.0299
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0087 0.0241 0.0653
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.003 0.0039 0.0039
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.003 0.0039 0.0119
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.0047 0.0281
Brugia malayi Cam kinase protein 1 0.0033 0.0048 0.0138
Entamoeba histolytica hypothetical protein 0.0023 0.0013 0.007
Trichomonas vaginalis hypothetical protein 0.0023 0.0011 0.0065
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0116 0.0691
Entamoeba histolytica pyruvate kinase, putative 0.0024 0.0017 0.0095
Schistosoma mansoni hypothetical protein 0.017 0.054 0.0742
Loa Loa (eye worm) hypothetical protein 0.0093 0.0265 0.0586
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0103 0.03 0.0412
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.058 0.3477
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.006 0.0185
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0137 0.091
Echinococcus granulosus calcium dependent protein kinase 0.003 0.0037 0.0049
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.058 0.3477
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0044 0.0088 0.058
Loa Loa (eye worm) doublecortin family protein 0.0041 0.0079 0.0174
Loa Loa (eye worm) hypothetical protein 0.0035 0.0055 0.0121
Mycobacterium ulcerans beta-lactamase 0.0439 0.1506 0.4277
Loa Loa (eye worm) hypothetical protein 0.0439 0.1506 0.3342
Brugia malayi Glycosyl hydrolases family 31 protein 0.0073 0.0193 0.0552
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0055 0.0121
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0044 0.0088 0.012
Toxoplasma gondii HEAT repeat-containing protein 0.0023 0.0011 0.0076
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0093 0.0265 0.0586
Trypanosoma cruzi pyruvate kinase 2, putative 0.0035 0.0055 0.0168
Trichomonas vaginalis glutathione reductase, putative 0.003 0.0039 0.023
Mycobacterium ulcerans acyl-CoA synthetase 0.0087 0.0241 0.0653
Plasmodium falciparum glutathione reductase 0.0087 0.0244 0.1617
Loa Loa (eye worm) hypothetical protein 0.0241 0.0796 0.1766
Loa Loa (eye worm) hypothetical protein 0.0093 0.0265 0.0586
Loa Loa (eye worm) hypothetical protein 0.0087 0.0241 0.0534
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0027 0.0028 0.0166
Plasmodium falciparum thioredoxin reductase 0.0087 0.0244 0.1617
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0033 0.0049 0.0049
Schistosoma mansoni protein kinase 0.0033 0.0048 0.0066
Echinococcus granulosus carboxylesterase 5A 0.0072 0.0187 0.0256
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.003 0.0039 0.0259
Brugia malayi beta-lactamase family protein 0.0439 0.1506 0.4298
Mycobacterium ulcerans esterase/lipase LipP 0.0439 0.1506 0.4277
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0097 0.0279 0.0278
Brugia malayi kap beta 3 protein 0.0023 0.0011 0.0032
Mycobacterium tuberculosis Conserved hypothetical protein 0.0163 0.0516 0.0516
Loa Loa (eye worm) histone methyltransferase 0.0046 0.0094 0.0207
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.002 0.0001 0.0004
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.003 0.0039 0.0259
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0293 0.0982 0.1347
Loa Loa (eye worm) hypothetical protein 0.0044 0.0088 0.0194
Schistosoma mansoni intermediate filament proteins 0.0026 0.0024 0.0034
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0048 0.0065
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0033 0.0048 0.0106
Loa Loa (eye worm) hypothetical protein 0.0093 0.0265 0.0586
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0029 0.0034 0.0224
Trypanosoma brucei glucose transporter, putative 0.0032 0.0045 0.0299
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.003 0.0039 0.0054
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.0615 0.3687
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0995 0.3505 0.7778
Schistosoma mansoni lamin 0.0026 0.0024 0.0034
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0087 0.0266
Loa Loa (eye worm) hypothetical protein 0.0439 0.1506 0.3342
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0056 0.0132 0.0181
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0093 0.0265 0.0362
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0093 0.0265 0.0362
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0093 0.0265 0.0362
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0294 0.1763
Loa Loa (eye worm) hypothetical protein 0.0093 0.0265 0.0586
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.006 0.0185
Trypanosoma brucei DNA polymerase eta, putative 0.0058 0.0137 0.091
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0027 0.0028 0.0166
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0048 0.0066
Loa Loa (eye worm) hypothetical protein 0.0044 0.0088 0.0194
Toxoplasma gondii FATC domain-containing protein 0.0026 0.0024 0.0159
Echinococcus granulosus translational activator gcn1 0.0023 0.0011 0.0015
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0073 0.0193 0.1091
Loa Loa (eye worm) hypothetical protein 0.0093 0.0265 0.0586
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.0121 0.0372
Echinococcus multilocularis PHD finger protein rhinoceros 0.0059 0.0144 0.0196
Mycobacterium ulcerans hypothetical protein 0.0439 0.1506 0.4277
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.006 0.0183
Onchocerca volvulus Bile acid receptor homolog 0.0093 0.0265 0.1753
Plasmodium vivax calcium-dependent protein kinase, putative 0.0033 0.0048 0.0317
Mycobacterium ulcerans hypothetical protein 0.0163 0.0516 0.1441
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0049 0.0107 0.0147
Trypanosoma brucei PAB1-binding protein , putative 0.0076 0.0204 0.1354
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0086 0.024 0.1435
Trypanosoma brucei protein kinase, putative 0.0108 0.0317 0.2101
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0048 0.0065
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0097 0.0278 0.1664
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0047 0.0281
Echinococcus granulosus histone acetyltransferase KAT2B 0.0086 0.024 0.0328
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0093 0.0265 0.0362
Brugia malayi RNA, U transporter 1 0.0339 0.1149 0.3279
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0093 0.0265 0.0586
Echinococcus granulosus tumor protein p63 0.0329 0.1112 0.1526
Trichomonas vaginalis D-aminoacylase, putative 0.0439 0.1506 0.9038
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0087 0.0241 0.0241
Echinococcus multilocularis thioredoxin glutathione reductase 0.0088 0.0246 0.0337
Loa Loa (eye worm) hypothetical protein 0.0174 0.0555 0.123
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.092 0.5521
Loa Loa (eye worm) beta-glucuronidase 0.0448 0.1539 0.3415
Schistosoma mansoni ap endonuclease 0.0097 0.0279 0.0382
Loa Loa (eye worm) hypothetical protein 0.0174 0.0555 0.123
Brugia malayi hypothetical protein 0.0174 0.0555 0.1583
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0084 0.0232 0.0725
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0039 0.0119
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0033 0.0048 0.0065
Mycobacterium ulcerans acetyl-CoA synthetase 0.0087 0.0241 0.0653
Echinococcus multilocularis Polycystic kidney disease protein 0.0041 0.0079 0.0107
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0031 0.0041 0.0056
Plasmodium vivax acetyl-CoA synthetase, putative 0.0087 0.0241 0.1597
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0031 0.0041 0.0231
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0512 0.1768 0.2426
Echinococcus multilocularis dna polymerase eta 0.0058 0.0137 0.0187
Brugia malayi isocitrate dehydrogenase 0.0033 0.0049 0.014
Trypanosoma brucei importin beta-1 subunit, putative 0.0119 0.0359 0.2383
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0031 0.0041 0.0118
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0093 0.0265 0.0362
Echinococcus granulosus mixed lineage leukemia protein mll 0.0037 0.0063 0.0085
Echinococcus granulosus thyroid hormone receptor alpha 0.0044 0.0088 0.012
Toxoplasma gondii lysine-tRNA ligase 0.0023 0.0013 0.0086
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0045 0.0299
Brugia malayi follicle stimulating hormone receptor 0.0227 0.0747 0.2132
Loa Loa (eye worm) hypothetical protein 0.0041 0.0079 0.0174
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0033 0.0048 0.0065
Loa Loa (eye worm) carboxylesterase 0.0072 0.0187 0.0414
Loa Loa (eye worm) hypothetical protein 0.0049 0.0107 0.0236
Leishmania major hypothetical protein, conserved 0.0439 0.1506 0.4716
Loa Loa (eye worm) hypothetical protein 0.0041 0.0079 0.0174
Echinococcus granulosus GTP binding nuclear protein Ran 0.0066 0.0167 0.0228
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0116 0.0346 0.0474
Loa Loa (eye worm) thioredoxin reductase 0.0087 0.0244 0.054
Echinococcus granulosus peregrin 0.0067 0.0169 0.0231
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0087 0.0241 0.16
Echinococcus granulosus lysyl tRNA synthetase 0.0023 0.0013 0.0017
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0033 0.0047 0.0281
Mycobacterium tuberculosis Conserved protein 0.0439 0.1506 0.1506
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0029 0.0034 0.1211
Trypanosoma brucei pyruvate kinase 1 0.0035 0.0055 0.0366
Trichomonas vaginalis penicillin-binding protein, putative 0.0439 0.1506 0.9038
Brugia malayi hypothetical protein 0.0049 0.0107 0.0305
Loa Loa (eye worm) hypothetical protein 0.0044 0.0088 0.0194
Entamoeba histolytica hypothetical protein 0.0512 0.1768 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.0088 0.0194
Brugia malayi AMP-binding enzyme family protein 0.0087 0.0241 0.0688
Echinococcus multilocularis FTZ F1 alpha 0.0093 0.0265 0.0362
Echinococcus granulosus lipoxygenase domain containing protein 0.0041 0.0079 0.0107
Schistosoma mansoni ran 0.0066 0.0167 0.0229
Trypanosoma cruzi fatty acid transporter protein-like, putative 0.0921 0.3237 1
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0044 0.0088 0.0121
Echinococcus granulosus histone acetyltransferase KAT2B 0.0285 0.0953 0.1306
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0147 0.0457 0.3032
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.0047 0.0281
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0087 0.0241 0.0743
Brugia malayi hypothetical protein 0.0512 0.1768 0.5045
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.092 0.5521
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0108 0.0317 0.0976
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0045 0.0267
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0097 0.0279 0.0859
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0037 0.0063 0.0085
Schistosoma mansoni smad1 5 8 and 0.0024 0.0016 0.0022
Trypanosoma cruzi importin beta-1 subunit, putative 0.0097 0.0278 0.0857
Brugia malayi Smad1 0.0024 0.0016 0.0046
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0087 0.0241 0.0753
Mycobacterium ulcerans acyl-CoA synthetase 0.0087 0.0241 0.0653
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0108 0.0317 0.0976
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0044 0.0088 0.012
Leishmania major 4-coumarate:coa ligase-like protein 0.0087 0.0241 0.0753
Schistosoma mansoni peptidase Clp (S14 family) 0.0084 0.0232 0.0318
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0237 0.078 0.107
Loa Loa (eye worm) hypothetical protein 0.0044 0.0088 0.0194
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0087 0.0241 0.136
Echinococcus multilocularis mitogen activated protein kinase 3 0.0108 0.0317 0.0434
Brugia malayi GH02984p 0.0075 0.02 0.057
Echinococcus granulosus neuropeptide receptor A26 0.0473 0.1629 0.2235
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0108 0.0317 0.0976
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0027 0.0029 0.0038
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0199 0.0646 0.0645
Schistosoma mansoni serine/threonine protein kinase 0.0033 0.0048 0.0066
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0087 0.0241 0.0753
Schistosoma mansoni jumonji/arid domain-containing protein 0.008 0.0218 0.0299
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0048 0.0066
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0194 0.0629 0.0862
Echinococcus granulosus FTZ F1 alpha 0.0093 0.0265 0.0362
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0031 0.0041 0.0118
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.006 0.0183
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0128 0.0391 0.0536
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0034 0.0053 0.0072
Onchocerca volvulus 0.0087 0.0241 0.1597
Trypanosoma cruzi polo-like protein kinase, putative 0.0101 0.0294 0.0907
Toxoplasma gondii NADPH-glutathione reductase 0.003 0.0039 0.0259
Schistosoma mansoni coup transcription factor 0.0093 0.0265 0.0363
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0306 0.103 0.1413
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0087 0.0241 0.0534
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0047 0.0281
Loa Loa (eye worm) MH1 domain-containing protein 0.0024 0.0016 0.0034
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0103 0.03 0.0412
Giardia lamblia Histone acetyltransferase GCN5 0.0079 0.0214 0.6749
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0237 0.078 0.107
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.002 0.0001 0.0002
Echinococcus granulosus neuropeptide s receptor 0.0473 0.1629 0.2235
Loa Loa (eye worm) hypothetical protein 0.0049 0.0107 0.0236
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0086 0.024 0.1587
Echinococcus multilocularis GPCR, family 2 0.0128 0.0391 0.0536
Loa Loa (eye worm) hypothetical protein 0.0087 0.0241 0.0534
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0034 0.0053 0.0072
Schistosoma mansoni loxhd1 0.0041 0.0079 0.0108
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0097 0.0278 0.1664
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0055 0.0362
Brugia malayi Doublecortin family protein 0.0041 0.0079 0.0225
Plasmodium vivax hypothetical protein, conserved 0.0059 0.0144 0.0949
Schistosoma mansoni hypothetical protein 0.1274 0.4506 0.6183
Onchocerca volvulus 0.0093 0.0265 0.1753
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0151 0.0208
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0049 0.0066
Brugia malayi Carboxylesterase family protein 0.0072 0.0187 0.0535
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0227 0.0747 0.1657
Plasmodium falciparum importin beta, putative 0.0119 0.0359 0.238
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0093 0.0265 0.0755
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.0013 0.0074
Schistosoma mansoni hypothetical protein 0.0128 0.0391 0.0537
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0439 0.1506 0.2067
Brugia malayi lysyl-tRNA synthetase 0.0023 0.0013 0.0037
Mycobacterium ulcerans acyl-CoA synthetase 0.0087 0.0241 0.0653
Loa Loa (eye worm) hypothetical protein 0.0027 0.0028 0.0061
Loa Loa (eye worm) pyruvate kinase-PB 0.0024 0.0017 0.0037
Echinococcus granulosus peptidase Clp S14 family 0.0055 0.0128 0.0175
Brugia malayi hypothetical protein 0.0076 0.0204 0.0582
Echinococcus multilocularis General substrate transporter 0.0089 0.0248 0.034
Entamoeba histolytica Ran family GTPase 0.0066 0.0167 0.0942
Entamoeba histolytica hypothetical protein 0.0512 0.1768 1
Schistosoma mansoni inositol transporter 0.0075 0.02 0.0274
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0087 0.0241 0.0753
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0066 0.0167 0.1109
Echinococcus granulosus acetylcholinesterase 0.0072 0.0187 0.0256
Loa Loa (eye worm) hypothetical protein 0.0439 0.1506 0.3342
Brugia malayi Steroid receptor seven-up type 2 0.0093 0.0265 0.0755
Loa Loa (eye worm) hypothetical protein 0.0102 0.0296 0.0655
Plasmodium vivax hexose transporter 0.0103 0.03 0.1991
Loa Loa (eye worm) hypothetical protein 0.0033 0.0048 0.0106
Brugia malayi nuclear hormone receptor 0.0044 0.0088 0.0251
Plasmodium falciparum histone acetyltransferase GCN5 0.0079 0.0214 0.1417
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.0317 0.1896
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0093 0.0265 0.0755
Entamoeba histolytica serine/threonine protein kinase, putative 0.0101 0.0294 0.1662
Trichomonas vaginalis D-aminoacylase, putative 0.0439 0.1506 0.9038
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0093 0.0265 0.0755
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0033 0.0048 0.0321
Schistosoma mansoni inositol transporter 0.0075 0.02 0.0274
Loa Loa (eye worm) hypothetical protein 0.0044 0.0088 0.0194
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.002 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0093 0.0265 0.0586
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0439 0.1506 0.2067
Trichomonas vaginalis maltase-glucoamylase, putative 0.0027 0.0028 0.0166
Plasmodium falciparum protein kinase 6 0.0439 0.1506 1
Trichomonas vaginalis esterase, putative 0.0439 0.1506 0.9038
Brugia malayi MH2 domain containing protein 0.0351 0.119 0.3395
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0137 0.091
Echinococcus granulosus mitogen activated protein kinase 0.0108 0.0317 0.0434
Plasmodium vivax proline--tRNA ligase, putative 0.0036 0.006 0.0393
Loa Loa (eye worm) hypothetical protein 0.0058 0.0137 0.0303
Leishmania major dihydrolipoamide dehydrogenase, putative 0.003 0.0039 0.012
Schistosoma mansoni hypothetical protein 0.0128 0.0391 0.0537
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0049 0.0066
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0221 0.0726 0.2271
Onchocerca volvulus 0.0439 0.1506 1
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0995 0.3505 1
Trichomonas vaginalis glycoside hydrolase, putative 0.0483 0.1667 1
Loa Loa (eye worm) oxidoreductase 0.0087 0.0241 0.0534
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0045 0.0137
Echinococcus multilocularis lipoxygenase domain containing protein 0.0041 0.0079 0.0107
Echinococcus multilocularis lysosomal alpha glucosidase 0.033 0.1116 0.1531
Entamoeba histolytica deoxycytidyl transferase, putative 0.0058 0.0137 0.0772
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0045 0.0299
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.0317 0.1896
Toxoplasma gondii histone lysine methyltransferase SET1 0.0281 0.0939 0.6231
Brugia malayi latrophilin 2 splice variant baaae 0.0277 0.0926 0.2643
Echinococcus granulosus dna polymerase eta 0.0058 0.0137 0.0187
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0087 0.0241 0.1597
Brugia malayi CXXC zinc finger family protein 0.0144 0.0447 0.1275
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0151 0.0208
Trypanosoma cruzi DNA polymerase kappa, putative 0.0058 0.0137 0.0422
Trichomonas vaginalis pyruvate kinase, putative 0.0035 0.0055 0.0327
Plasmodium falciparum calcium-dependent protein kinase 4 0.0033 0.0048 0.0317
Schistosoma mansoni hypothetical protein 0.2048 0.7287 1
Schistosoma mansoni protein kinase 0.0033 0.0048 0.0066
Onchocerca volvulus 0.0144 0.0447 0.2964
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0033 0.0049 0.015
Plasmodium falciparum transportin 0.0023 0.0011 0.0071
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0097 0.0279 0.0617
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0073 0.0193 0.1091
Brugia malayi MAP kinase sur-1 0.0108 0.0317 0.0903
Brugia malayi hypothetical protein 0.0049 0.0107 0.0305
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.092 0.5521
Echinococcus multilocularis ecdysone induced protein 78C 0.0093 0.0265 0.0362
Loa Loa (eye worm) hypothetical protein 0.0119 0.0359 0.0795
Schistosoma mansoni terminal deoxycytidyl transferase 0.0058 0.0137 0.0188
Trichomonas vaginalis alpha-glucosidase, putative 0.0073 0.0193 0.1157
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0087 0.0241 0.0653
Echinococcus granulosus TGF beta signal transducer SmadC 0.0024 0.0016 0.0021
Echinococcus granulosus survival motor neuron protein 1 0.0241 0.0796 0.1092
Echinococcus granulosus tar DNA binding protein 0.0062 0.0151 0.0207
Schistosoma mansoni importin-beta 2 0.0023 0.0011 0.0016
Echinococcus multilocularis nuclear receptor nhr 48 0.0044 0.0088 0.012
Entamoeba histolytica protein kinase, putative 0.0033 0.0048 0.0269
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0128 0.0391 0.1117
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0033 0.0049 0.0066
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0024 0.0053
Entamoeba histolytica hypothetical protein 0.0512 0.1768 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0237 0.078 0.1071
Brugia malayi Pyruvate kinase, muscle isozyme 0.0035 0.0055 0.0157
Leishmania major pantothenate kinase subunit, putative 0.0032 0.0044 0.0135
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0084 0.0232 0.0628
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0221 0.0726 0.0725
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0087 0.0241 0.0653
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0093 0.0265 0.1753
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0093 0.0265 0.0362
Schistosoma mansoni eyes absent homolog 0.0174 0.0555 0.0761
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.0317 0.1896
Loa Loa (eye worm) hypothetical protein 0.0033 0.0048 0.0106
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0087 0.0244 0.0244
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.002 0.0001 0.0002
Echinococcus multilocularis peptidase Clp (S14 family) 0.0055 0.0128 0.0175
Echinococcus multilocularis lipoxygenase domain containing protein 0.0041 0.0079 0.0107
Plasmodium vivax thioredoxin reductase, putative 0.0087 0.0244 0.1616
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0049 0.0107 0.0236
Loa Loa (eye worm) hypothetical protein 0.0028 0.0029 0.0064
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.092 0.5521
Mycobacterium ulcerans glutaminase 0.0278 0.0929 0.2624
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0087 0.0241 0.0753
Echinococcus multilocularis importin subunit beta 1 0.0119 0.0359 0.0492
Brugia malayi glutaminase DH11.1 0.0278 0.0929 0.2651
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0087 0.0241 0.0743
Mycobacterium tuberculosis Probable hydrolase 0.0439 0.1506 0.1506
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.031 0.1043 0.3219
Brugia malayi Beta-glucuronidase precursor 0.0448 0.1539 0.4392
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0075 0.02 0.0273
Brugia malayi nuclear receptor NHR-88 0.0093 0.0265 0.0755
Schistosoma mansoni polycystin 1-related 0.0041 0.0079 0.0108
Loa Loa (eye worm) hypothetical protein 0.0044 0.0088 0.0194
Echinococcus multilocularis smad 0.0024 0.0016 0.0021
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.002 0.0001 0.0002
Schistosoma mansoni RAR-like nuclear receptor 0.0093 0.0265 0.0363
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0097 0.0279 0.0381
Leishmania major pyruvate kinase 0.0035 0.0055 0.0171
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0047 0.0281
Echinococcus granulosus thioredoxin glutathione reductase 0.0088 0.0246 0.0337
Schistosoma mansoni rab6-interacting 0.0041 0.0079 0.0108
Mycobacterium ulcerans acyl-CoA synthetase 0.0087 0.0241 0.0653
Onchocerca volvulus 0.0087 0.0241 0.1597
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0087 0.0241 0.0743
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0039 0.0119
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0033 0.0048 0.0317
Mycobacterium ulcerans DNA polymerase IV 0.0058 0.0137 0.0356
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0084 0.0232 0.8328
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0072 0.0187 0.0257
Plasmodium falciparum calcium-dependent protein kinase 3 0.0033 0.0048 0.0317
Loa Loa (eye worm) DR-78 0.0044 0.0088 0.0194
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0237 0.078 0.1731
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0023 0.0013 0.0038
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0055 0.0121
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0048 0.0065
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0035 0.0055 0.0055
Plasmodium vivax pyruvate kinase, putative 0.0035 0.0055 0.0362
Loa Loa (eye worm) hypothetical protein 0.0044 0.0088 0.0194
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0055 0.0128 0.0128
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.002 0.0001 0.0004
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0151 0.0335
Schistosoma mansoni protein kinase 0.0033 0.0048 0.0066
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0108 0.0317 0.2101
Onchocerca volvulus Serine\/threonine kinase homolog 0.0101 0.0294 0.195
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.0317 0.1896
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0058 0.0137 0.0137
Echinococcus multilocularis isocitrate dehydrogenase 0.0033 0.0049 0.0066
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0039 0.0119
Brugia malayi AMP-binding enzyme family protein 0.0087 0.0241 0.0688
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0093 0.0265 0.0363
Echinococcus granulosus lamin 0.0026 0.0024 0.0033
Onchocerca volvulus 0.0098 0.0284 0.188
Trichomonas vaginalis pyruvate kinase, putative 0.0035 0.0055 0.0327
Trypanosoma cruzi DNA polymerase kappa, putative 0.0058 0.0137 0.0422
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0087 0.0241 0.0653
Loa Loa (eye worm) glutathione reductase 0.0087 0.0244 0.054
Trichomonas vaginalis ap endonuclease, putative 0.0097 0.0279 0.1668
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0193 0.0596
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0075 0.02 0.0273
Leishmania major hypothetical protein, conserved 0.0023 0.0011 0.0034
Brugia malayi conserved hypotetical protein 0.0044 0.0088 0.0251
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0093 0.0265 0.0363
Loa Loa (eye worm) hypothetical protein 0.0406 0.1387 0.3078
Schistosoma mansoni high-affinity choline transporter 0.0075 0.02 0.0274
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0087 0.0241 0.0743
Brugia malayi hypothetical protein 0.0044 0.0088 0.0251
Trichomonas vaginalis antibiotic synthetase, putative 0.0087 0.0241 0.1443
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0087 0.0241 0.0241
Loa Loa (eye worm) pyruvate kinase 0.0035 0.0055 0.0121
Brugia malayi nuclear hormone receptor 0.0093 0.0265 0.0755
Echinococcus granulosus long chain fatty acid transport protein 4 0.0921 0.3237 0.4442
Loa Loa (eye worm) jmjC domain-containing protein 0.008 0.0218 0.0482
Trichomonas vaginalis maltase-glucoamylase, putative 0.0073 0.0193 0.1157
Plasmodium vivax ataxin-2 like protein, putative 0.0076 0.0204 0.135
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0066 0.0167 0.0228
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0176 0.0564 0.0773
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0073 0.0193 0.1284
Trypanosoma brucei glucose transporter, putative 0.0032 0.0045 0.0299
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0033 0.0049 0.0067
Brugia malayi tailless protein 0.0044 0.0088 0.0251
Trichomonas vaginalis antibiotic synthetase, putative 0.0087 0.0241 0.1443
Loa Loa (eye worm) hypothetical protein 0.0084 0.0232 0.0514
Brugia malayi jmjC domain containing protein 0.0194 0.0629 0.1794
Loa Loa (eye worm) hypothetical protein 0.0128 0.0391 0.0867
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0093 0.0265 0.0755
Mycobacterium ulcerans pyruvate kinase 0.0035 0.0055 0.0121
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0137 0.091
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.006 0.0397
Onchocerca volvulus Pyruvate kinase homolog 0.0035 0.0055 0.0362
Onchocerca volvulus 0.0044 0.0088 0.058
Loa Loa (eye worm) PHD-finger family protein 0.0059 0.0144 0.0317
Giardia lamblia Prolyl-tRNA synthetase 0.0031 0.0041 0.129
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0066 0.0167 0.1106
Brugia malayi AMP-binding enzyme family protein 0.0087 0.0241 0.0688
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0176 0.0564 0.0773
Brugia malayi hypothetical protein 0.0241 0.0796 0.2272
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.003 0.0039 0.0075
Brugia malayi PHD-finger family protein 0.0028 0.0029 0.0084
Brugia malayi Bromodomain containing protein 0.0067 0.0169 0.0483
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0128 0.0391 0.0536
Onchocerca volvulus 0.0041 0.0079 0.052
Echinococcus multilocularis dnaJ subfamily B 0.2048 0.7287 1
Echinococcus granulosus RUN 0.0041 0.0079 0.0107
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0044 0.0088 0.012
Schistosoma mansoni nuclear receptor nhr-48 0.0044 0.0088 0.0121
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0087 0.0241 0.0241
Brugia malayi Nuclear hormone receptor-like 1 0.0049 0.0107 0.0305
Trypanosoma brucei unspecified product 0.004 0.0073 0.0484
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0294 0.1763
Echinococcus multilocularis importin 5 0.0023 0.0011 0.0015
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.002 0.0001 0.0004
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0031 0.0041 0.0056
Schistosoma mansoni cript-related 0.002 0.0001 0.0001
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0031 0.0041 0.0128
Onchocerca volvulus 0.0044 0.0088 0.058
Echinococcus multilocularis lysosomal alpha glucosidase 0.033 0.1116 0.1531
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0093 0.0265 0.0586
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0087 0.0241 0.0653
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0084 0.0232 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0439 0.1506 0.1506
Onchocerca volvulus 0.0439 0.1506 1
Entamoeba histolytica hypothetical protein 0.0097 0.0278 0.1569
Loa Loa (eye worm) hypothetical protein 0.0087 0.0241 0.0534
Schistosoma mansoni nuclear receptor 0.0044 0.0088 0.0121
Schistosoma mansoni nuclear receptor 0.0044 0.0088 0.0121
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.058 0.3477
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0237 0.078 0.107
Echinococcus granulosus PHD finger protein rhinoceros 0.0059 0.0144 0.0196
Loa Loa (eye worm) hypothetical protein 0.0291 0.0976 0.2165
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0137 0.091
Loa Loa (eye worm) hypothetical protein 0.0087 0.0241 0.0534
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0087 0.0241 0.0653
Echinococcus granulosus neutral alpha glucosidase AB 0.0073 0.0193 0.0265
Trichomonas vaginalis sucrase-isomaltase, putative 0.0073 0.0193 0.1157
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0116 0.0691
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0221 0.0726 0.0725
Leishmania major glucose transporter, lmgt2 0.0032 0.0045 0.0139

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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