Detailed information for compound 828942

Basic information

Technical information
  • TDR Targets ID: 828942
  • Name: N-[2-(bis(2-methylpropyl)amino)ethyl]-6-methy l-4,5,6,7-tetrahydro-1-benzothiophene-3-carbo xamide
  • MW: 350.562 | Formula: C20H34N2OS
  • H donors: 1 H acceptors: 1 LogP: 5.24 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(CN(CC(C)C)CCNC(=O)c1csc2c1CCC(C2)C)C
  • InChi: 1S/C20H34N2OS/c1-14(2)11-22(12-15(3)4)9-8-21-20(23)18-13-24-19-10-16(5)6-7-17(18)19/h13-16H,6-12H2,1-5H3,(H,21,23)
  • InChiKey: KVHHUSZWLRQEHX-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

  • N-[2-(diisobutylamino)ethyl]-6-methyl-4,5,6,7-tetrahydrobenzothiophene-3-carboxamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0096 0.0144
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0119 0.0809 0.1764
Brugia malayi Pre-SET motif family protein 0.0093 0.0624 0.1362
Trichomonas vaginalis mercuric reductase, putative 0.0013 0.0051 0.0073
Plasmodium vivax basic transcription factor 3b, putative 0.0072 0.0475 0.7602
Brugia malayi CXXC zinc finger family protein 0.003 0.0169 0.0369
Echinococcus multilocularis dna polymerase eta 0.0019 0.0096 0.0083
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0119 0.0809 0.1764
Echinococcus multilocularis cpg binding protein 0.0031 0.0181 0.0169
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0013 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0027 0.0035
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0115 0.0102
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0197 0.0353
Mycobacterium tuberculosis Probable dehydrogenase 0.0087 0.0578 0.1854
Trypanosoma cruzi hexose transporter, putative 0.001 0.0027 0.0126
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0008 0.0013 0.0061
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0038 0.0229 0.0709
Echinococcus multilocularis mitogen activated protein kinase 0.0107 0.0721 0.0709
Echinococcus granulosus synaptic vesicle 2 protein 0.001 0.0027 0.0014
Brugia malayi pyruvate kinase 0.0007 0.0007 0.0016
Giardia lamblia Kinase, CMGC MAPK 0.0107 0.0721 0.1142
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0008 0.0013 0.0043
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0107 0.0721 0.3383
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0888 0.6316 1
Loa Loa (eye worm) hypothetical protein 0.0008 0.0013 0.0028
Onchocerca volvulus 0.0735 0.5222 1
Mycobacterium ulcerans integral membrane transport protein 0.001 0.0027 0.0088
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0008 0.0013 0.0021
Loa Loa (eye worm) phosphofructokinase 0.0112 0.0761 0.166
Leishmania major hypothetical protein, conserved 0.0008 0.0013 0.0061
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0197 0.0305
Trichomonas vaginalis steroid dehydrogenase, putative 0.0008 0.0013 0.0013
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0149 0.313
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0063 0.0406 0.1288
Leishmania major DNA polymerase eta, putative 0.0019 0.0096 0.045
Loa Loa (eye worm) hypothetical protein 0.0008 0.0013 0.0028
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0112 0.0761 0.3567
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0119 0.0809 0.0796
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0093 0.0624 0.0624
Trichomonas vaginalis glucose transporter, putative 0.001 0.0027 0.0035
Loa Loa (eye worm) thioredoxin reductase 0.0038 0.0229 0.05
Trypanosoma brucei cytochrome P450, putative 0.0013 0.0048 0.0224
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0059
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0043 0.0263 0.1232
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0005 0.000000000042566
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0149 0.238
Echinococcus multilocularis solute carrier family 22 0.001 0.0027 0.0014
Leishmania major quinonoid dihydropteridine reductase 0.0008 0.0013 0.0061
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0013 0.0028
Leishmania major mitochondrial DNA polymerase beta 0.0304 0.2133 1
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0013 0.0013
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0096 0.045
Brugia malayi intermediate filament protein 0.0027 0.015 0.0327
Schistosoma mansoni sugar transporter 0.001 0.0027 0.0027
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0008 0.0013 0.0043
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0888 0.6316 1
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0013 0.0013
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0008 0.0013 0.0028
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0174 0.8415
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Trypanosoma brucei pyruvate kinase 1 0.0034 0.0197 0.0925
Leishmania major hypothetical protein, conserved 0.0008 0.0013 0.0061
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0025 0.0135 0.1868
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0174 0.0268
Schistosoma mansoni cpg binding protein 0.0031 0.0181 0.0181
Toxoplasma gondii sugar transporter ST1 0.001 0.0027 0.0374
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0013 0.0028
Onchocerca volvulus 0.001 0.0027 0.0027
Brugia malayi POT family protein 0.0082 0.0541 0.118
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0008 0.0013 0.0043
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0013 0.0013
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0096 0.045
Schistosoma mansoni transcription factor btf3 0.0072 0.0475 0.0475
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0013 0.0051 0.108
Leishmania major hypothetical protein, conserved 0.0008 0.0013 0.0061
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0174 0.2787
Loa Loa (eye worm) CYP4Cod1 0.0013 0.0048 0.0104
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0434 0.3063 1
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0027 0.0035
Schistosoma mansoni lamin 0.0027 0.015 0.015
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0093 0.0624 0.0612
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0025 0.0135 0.044
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0013 0.0013
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.001 0.0027 0.1143
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0022 0.0048
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0117 0.0792 0.2585
Loa Loa (eye worm) histone methyltransferase 0.0013 0.0047 0.0102
Loa Loa (eye worm) hypothetical protein 0.0008 0.0013 0.0028
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0761 0.1198
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0013 0.0013
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0013 0.0028
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0013 0.0051 0.0125
Leishmania major pyruvate kinase 0.0034 0.0197 0.0925
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0013 0.0051 0.024
Schistosoma mansoni carbonyl reductase 0.0008 0.0013 0.0013
Schistosoma mansoni microtubule-associated protein tau 0.1403 1 1
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.001 0.0026 0.0057
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0013 0.0013
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.001 0.0027 0.0126
Echinococcus multilocularis solute carrier family 22 0.001 0.0027 0.0014
Loa Loa (eye worm) oxidoreductase 0.0008 0.0013 0.0028
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0112 0.0761 0.2451
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0013 0.0051 0.0821
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0013 0.0051 0.3141
Leishmania major hypothetical protein, conserved 0.0009 0.0024 0.0112
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0013 0.0047 0.0034
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0008 0.0013 0.0061
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0169 0.0369
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0022 0.0305
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.001 0.0027 0.0014
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0041 0.0193
Echinococcus multilocularis geminin 0.0169 0.117 0.1158
Brugia malayi hypothetical protein 0.001 0.0027 0.0059
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0119 0.0809 0.0796
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0096 0.0096
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0013 0.0013
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0107 0.0721 0.3383
Trichomonas vaginalis CMGC family protein kinase 0.0107 0.0721 0.1135
Plasmodium vivax SET domain protein, putative 0.0093 0.0624 1
Mycobacterium tuberculosis Probable reductase 0.0087 0.0578 0.1854
Mycobacterium ulcerans short-chain dehydrogenase 0.0008 0.0013 0.0043
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.006 0.0131
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0013 0.0013
Echinococcus multilocularis pyruvate kinase 0.0017 0.008 0.0067
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0135 0.2158
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0135 0.2838
Leishmania major pteridine reductase 1 0.0008 0.0013 0.0061
Loa Loa (eye worm) hypothetical protein 0.0013 0.0046 0.0101
Loa Loa (eye worm) cytochrome P450 family protein 0.0013 0.0048 0.0104
Echinococcus granulosus Sugar transporter ERD6 protein 0.001 0.0027 0.0014
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0013 0.0028
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0013 0.0051 0.024
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.0005 0.000000000042566
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0027 0.0035
Chlamydia trachomatis pyruvate kinase 0.0034 0.0197 1
Schistosoma mansoni sugar transporter 0.001 0.0027 0.0027
Onchocerca volvulus Putative transporter 0.001 0.0027 0.0027
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0174 0.0268
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0008 0.0013 0.0028
Loa Loa (eye worm) RecQ helicase 0.0022 0.0115 0.025
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0013 0.0043
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0008 0.0013 0.0061
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.001 0.0027 0.0014
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0013 0.0043
Brugia malayi hypothetical protein 0.001 0.0027 0.0059
Trypanosoma brucei short-chain dehydrogenase, putative 0.0008 0.0013 0.0061
Leishmania major hypothetical protein, conserved 0.001 0.0027 0.0126
Brugia malayi hypothetical protein 0.001 0.0027 0.0059
Leishmania major glucose transporter, lmgt2 0.001 0.0027 0.0126
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0115 0.0174
Trypanosoma brucei glucose transporter, putative 0.001 0.0027 0.0126
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0096 0.045
Leishmania major short chain dehydrogenase, putative 0.0008 0.0013 0.0061
Echinococcus multilocularis pyruvate kinase 0.0017 0.008 0.0067
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0013 0.0048 0.0156
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0088 0.0589 0.1286
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.001 0.0026 0.0057
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0093 0.0624 0.0624
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0013 0.0181
Toxoplasma gondii oxidoreductase, putative 0.0008 0.0013 0.0181
Onchocerca volvulus 0.001 0.0027 0.0027
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0888 0.6316 1
Mycobacterium ulcerans sugar transporter 0.001 0.0027 0.0088
Leishmania major quinonoid dihydropteridine reductase 0.0008 0.0013 0.0061
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0117 0.0792 0.2585
Brugia malayi hypothetical protein 0.0027 0.0149 0.0324
Loa Loa (eye worm) oxidoreductase 0.0008 0.0013 0.0028
Brugia malayi Pre-SET motif family protein 0.0646 0.4583 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0093 0.0624 0.0612
Loa Loa (eye worm) hypothetical protein 0.0027 0.0149 0.0324
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0012 0.0043 0.003
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0013 0.0043
Schistosoma mansoni glucose transport protein 0.001 0.0027 0.0027
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0096 0.0313
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0015 0.0064 0.1018
Plasmodium falciparum thioredoxin reductase 0.0038 0.0229 0.4832
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0174 0.0268
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0174 0.2413
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0888 0.6316 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0008 0.0013 0.0043
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0013 0.0181
Loa Loa (eye worm) hypothetical protein 0.0013 0.0046 0.0101
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0013 0.0043
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0013 0.0043
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0022 0.0048
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0761 0.1198
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0041 0.0193
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0013 0.0043
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0013 0.0051 0.024
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0117 0.0792 0.078
Echinococcus multilocularis microtubule associated protein 2 0.1403 1 1
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0149 0.0697
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0135 0.0632
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0052 0.033 0.1546
Leishmania major cytochrome p450-like protein 0.0013 0.0048 0.0224
Trypanosoma brucei pyruvate kinase 1, putative 0.0034 0.0197 0.0925
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.005 0.0037
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Echinococcus multilocularis mitogen activated protein kinase 3 0.0107 0.0721 0.0709
Loa Loa (eye worm) hypothetical protein 0.0008 0.0013 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0475 0.0744
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0174 0.0196
Trypanosoma cruzi hypothetical protein, conserved 0.0008 0.0013 0.0061
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0013 0.0028
Loa Loa (eye worm) hypothetical protein 0.0019 0.0096 0.0209
Mycobacterium leprae Probable pyruvate kinase PykA 0.0034 0.0197 0.0604
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Loa Loa (eye worm) sugar transporter 0.001 0.0027 0.0059
Trypanosoma cruzi hypothetical protein, conserved 0.0008 0.0013 0.0061
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0059
Toxoplasma gondii transporter, major facilitator family protein 0.001 0.0027 0.0374
Trypanosoma cruzi hypothetical protein, conserved 0.0008 0.0013 0.0061
Loa Loa (eye worm) dehydrogenase 0.0008 0.0013 0.0028
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0008 0.0013 0.0013
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0117 0.0792 0.3713
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0013 0.0013
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0013 0.0013
Giardia lamblia NADH oxidase lateral transfer candidate 0.0013 0.0051 0.0081
Echinococcus multilocularis lamin dm0 0.0027 0.015 0.0137
Brugia malayi Major Facilitator Superfamily protein 0.001 0.0027 0.0059
Echinococcus granulosus geminin 0.0169 0.117 0.1158
Schistosoma mansoni glucose transport protein 0.001 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0009 0.0022 0.0048
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0406 0.1325
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0009 0.0022 0.0009
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0013 0.0051 0.0038
Brugia malayi Dehydrogenases, short chain protein 2 0.0008 0.0013 0.0028
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.0005 0.000000000042566
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.0124 0.0177
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0009 0.0022 0.0009
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0025 0.0135 0.0399
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0008 0.0013 0.0043
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0013 0.0028
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.0761 0.1186
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0304 0.2133 1
Trichomonas vaginalis set domain proteins, putative 0.0735 0.5222 0.8266
Leishmania major quinonoid dihydropteridine reductase 0.0008 0.0013 0.0061
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0197 0.0925
Onchocerca volvulus 0.001 0.0027 0.0027
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0013 0.0013
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Leishmania major glucose transporter, lmgt3 0.001 0.0027 0.0126
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0013 0.0013
Leishmania major quinonoid dihydropteridine reductase 0.0008 0.0013 0.0061
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0013 0.0028
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0059
Onchocerca volvulus 0.001 0.0027 0.0027
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0096 0.045
Plasmodium falciparum pyruvate kinase 2 0.0017 0.008 0.1689
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.006 0.0131
Trypanosoma brucei glucose transporter, putative 0.001 0.0027 0.0126
Echinococcus granulosus solute carrier family 22 0.001 0.0027 0.0014
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0008 0.0013 0.0043
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0304 0.2133 1
Plasmodium vivax thioredoxin reductase, putative 0.0038 0.0229 0.3673
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0112 0.0761 0.2451
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0059
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0434 0.3063 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0124 0.0272
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0093 0.0624 0.8656
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0097 0.0648 0.2081
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0096 0.045
Brugia malayi Cytochrome P450 family protein 0.0013 0.0048 0.0104
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0013 0.0051 0.0051
Schistosoma mansoni 6-phosphofructokinase 0.0112 0.0761 0.0761
Loa Loa (eye worm) oxidoreductase 0.0008 0.0013 0.0028
Plasmodium falciparum hexose transporter 0.001 0.0027 0.0568
Trichomonas vaginalis DNA helicase recq, putative 0.0012 0.0041 0.0057
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0009 0.0022 0.0009
Brugia malayi phosphofructokinase 0.0112 0.0761 0.166
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0013 0.0051 0.108
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0096 0.0272
Onchocerca volvulus 0.0088 0.0589 0.1106
Loa Loa (eye worm) oxidoreductase 0.0008 0.0013 0.0028
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0013 0.0051 0.0038
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0013 0.0043
Mycobacterium ulcerans hypothetical protein 0.016 0.1103 0.36
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Mycobacterium ulcerans short-chain dehydrogenase 0.0008 0.0013 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0027 0.0035
Leishmania major hypothetical protein, conserved 0.0008 0.0013 0.0061
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0059
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0013 0.0028
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0888 0.6316 1
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0174 0.0268
Onchocerca volvulus 0.001 0.0027 0.0027
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0013 0.0043
Toxoplasma gondii facilitative glucose transporter GT1 0.001 0.0027 0.0374
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0888 0.6316 1
Loa Loa (eye worm) POT family protein 0.0082 0.0541 0.118
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0008 0.0013 0.0043
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0013 0.0043
Plasmodium falciparum glutathione reductase 0.0013 0.0051 0.108
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0008 0.0013 0.0061
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0051 0.024
Leishmania major glucose transporter, lmgt1 0.001 0.0027 0.0126
Leishmania major trypanothione reductase 0.0038 0.0229 0.1076
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0013 0.0051 0.0167
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0406 0.0406
Brugia malayi Dehydrogenases, short chain protein 30 0.0008 0.0013 0.0028
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0096 0.0083
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Brugia malayi 6-phosphofructokinase 0.0112 0.0761 0.166
Loa Loa (eye worm) hypothetical protein 0.0008 0.0013 0.0028
Entamoeba histolytica transcription factor BTF3, putative 0.0072 0.0475 0.0732
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0761 0.1198
Schistosoma mansoni sugar transporter 0.001 0.0027 0.0027
Echinococcus granulosus thioredoxin glutathione reductase 0.0039 0.0233 0.022
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0059
Toxoplasma gondii sugar transporter ST3 0.001 0.0027 0.0374
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0013 0.0028
Trypanosoma brucei short-chain dehydrogenase, putative 0.0008 0.0013 0.0061
Loa Loa (eye worm) ICD-1 protein 0.0072 0.0475 0.1036
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0888 0.6316 1
Leishmania major quinonoid dihydropteridine reductase 0.0008 0.0013 0.0061
Loa Loa (eye worm) hypothetical protein 0.0008 0.0013 0.0028
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0013 0.0028
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0005 0.000000000042566
Trypanosoma cruzi short chain dehydrogenase, putative 0.0008 0.0013 0.0061
Leishmania major glucose transporter/membrane transporter D2, putative 0.001 0.0027 0.0126
Treponema pallidum fructose-bisphosphate aldolase 0.0888 0.6316 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0059
Trichomonas vaginalis CMGC family protein kinase 0.0107 0.0721 0.1135
Echinococcus multilocularis musashi 0.0027 0.015 0.0137
Echinococcus multilocularis synaptic vesicle 2 protein 0.001 0.0027 0.0014
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0008 0.0013 0.0061
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0008 0.0013 0.0043
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0013 0.0051 0.0167
Onchocerca volvulus 0.003 0.0169 0.03
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0013 0.0013
Loa Loa (eye worm) oxidoreductase 0.0008 0.0013 0.0028
Trypanosoma brucei THT1 - hexose transporter, putative 0.001 0.0027 0.0126
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0013 0.0051 0.024
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0059
Plasmodium vivax glutathione reductase, putative 0.0038 0.0229 0.3673
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0013 0.0013
Echinococcus granulosus mitogen activated protein kinase 0.0107 0.0721 0.0709
Leishmania major short chain dehydrogenase-like protein 0.0008 0.0013 0.0061
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0149 0.0697
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0009 0.0022 0.0048
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.001 0.0027 0.0046
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0093 0.0624 0.0624
Schistosoma mansoni glucose transport protein 0.001 0.0027 0.0027
Trypanosoma cruzi short chain dehydrogenase, putative 0.0008 0.0013 0.0061
Loa Loa (eye worm) hypothetical protein 0.0093 0.0624 0.1362
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0096 0.045
Leishmania major short chain dehydrogenase/reductase, putative 0.0008 0.0013 0.0061
Trypanosoma brucei unspecified product 0.0019 0.0096 0.045
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0008 0.0013 0.0181
Schistosoma mansoni DNA helicase recq5 0.0009 0.0022 0.0022
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0013 0.0013
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0087 0.0578 0.1854
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0008 0.0013 0.0061
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0174 0.0255
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0174 0.3666
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0063 0.0406 0.0393
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0008 0.0013 0.0181
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0197 0.043
Brugia malayi major facilitator superfamily protein 0.001 0.0027 0.0059
Mycobacterium ulcerans pyruvate kinase 0.0034 0.0197 0.0644
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0096 0.045
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0149 0.313
Plasmodium vivax hypothetical protein, conserved 0.0008 0.0013 0.0209
Loa Loa (eye worm) hypothetical protein 0.0088 0.0589 0.1286
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0096 0.045
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0107 0.0721 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0066 0.0432 0.0432
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0013 0.0043
Brugia malayi glutathione reductase 0.0038 0.0229 0.05
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0059
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0107 0.0721 0.1574
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0119 0.0809 0.0796
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0013 0.0013
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0013 0.0013
Echinococcus granulosus L aminoadipate semialdehyde 0.0088 0.0589 0.0577
Giardia lamblia DINP protein human, muc B family 0.0019 0.0096 0.0152
Loa Loa (eye worm) cytochrome P450 family protein 0.0013 0.0048 0.0104
Echinococcus granulosus pyruvate kinase 0.0034 0.0197 0.0184
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0112 0.0761 0.1133
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0096 0.0272
Brugia malayi hypothetical protein 0.0008 0.0013 0.0028
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0434 0.3063 1
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0107 0.0721 0.3383
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0025 0.0135 0.044
Echinococcus granulosus pyruvate kinase 0.0017 0.008 0.0067
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0888 0.6316 1
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0081 0.0081
Toxoplasma gondii oxidoreductase, putative 0.0008 0.0013 0.0181
Echinococcus multilocularis 6 phosphofructokinase 0.0112 0.0761 0.0749
Giardia lamblia Reductase, putative 0.0008 0.0013 0.0021
Toxoplasma gondii NADPH-glutathione reductase 0.0013 0.0051 0.0711
Brugia malayi hypothetical protein 0.0008 0.0013 0.0028
Onchocerca volvulus 0.001 0.0027 0.0027
Entamoeba histolytica dual specificity protein phosphatase, putative 0.0583 0.4133 0.6537
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Brugia malayi Cytochrome P450 family protein 0.0013 0.0048 0.0104
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0013 0.0051 0.0112
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.001 0.0027 0.0014
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0013 0.0043
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0005 0.000000000042566
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0096 0.045
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0197 0.043
Toxoplasma gondii pyruvate kinase PyK1 0.0034 0.0197 0.2733
Trypanosoma cruzi cytochrome P450, putative 0.0013 0.0048 0.0224
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0008 0.0013 0.0061
Trypanosoma cruzi hypothetical protein, conserved 0.0008 0.0013 0.0061
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0013 0.0051 0.024
Mycobacterium ulcerans ketoacyl reductase 0.0008 0.0013 0.0043
Giardia lamblia Short-chain dehydrogenase, putative 0.0008 0.0013 0.0021
Schistosoma mansoni carbonyl reductase 0.0008 0.0013 0.0013
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0107 0.0721 0.3383
Trypanosoma cruzi trypanothione reductase, putative 0.0038 0.0229 0.1076
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0197 0.0925
Echinococcus multilocularis solute carrier family 22 0.001 0.0027 0.0014
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0059
Schistosoma mansoni sugar transporter 0.001 0.0027 0.0027
Trichomonas vaginalis pps1 dual specificty phosphatase, putative 0.0583 0.4133 0.6541
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0059
Plasmodium falciparum glutathione reductase 0.0038 0.0229 0.4832
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0008 0.0013 0.0043
Plasmodium falciparum thioredoxin reductase 0.0013 0.0051 0.108
Loa Loa (eye worm) sugar transporter 0.001 0.0027 0.0059
Plasmodium falciparum pyruvate kinase 0.0034 0.0197 0.4153
Echinococcus granulosus intermediate filament protein 0.0027 0.015 0.0137
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.001 0.0027 0.0046
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0008 0.0013 0.0043
Schistosoma mansoni pyruvate kinase 0.0034 0.0197 0.0197
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0096 0.0083
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0174 0.8415
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0013 0.0013
Trichomonas vaginalis CMGC family protein kinase 0.0107 0.0721 0.1135
Leishmania major hypothetical protein, conserved 0.0027 0.0149 0.0697
Toxoplasma gondii NAC domain-containing protein 0.0072 0.0475 0.6581
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0059
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.0761 0.1186
Echinococcus granulosus solute carrier family 22 0.001 0.0027 0.0014
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0051 0.024
Schistosoma mansoni carbonyl reductase 0.0008 0.0013 0.0013
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0013 0.0013
Onchocerca volvulus 0.001 0.0027 0.0027
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.001 0.0027 0.0014
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0174 0.0268
Echinococcus multilocularis Sugar transporter ERD6 protein 0.001 0.0027 0.0014
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0008 0.0013 0.0061
Loa Loa (eye worm) hypothetical protein 0.0008 0.0013 0.0028
Leishmania major myo-inositol/proton symporter (MIT) 0.001 0.0027 0.0126
Brugia malayi Thioredoxin reductase 0.0038 0.0229 0.05
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0096 0.045
Echinococcus granulosus transcription factor btf3 0.0072 0.0475 0.0462
Loa Loa (eye worm) major facilitator superfamily transporter 0.001 0.0027 0.0059
Echinococcus multilocularis pyruvate kinase 0.0026 0.0147 0.0134
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0013 0.0028
Mycobacterium ulcerans ketoacyl reductase 0.0008 0.0013 0.0043
Trypanosoma cruzi hypothetical protein, conserved 0.0008 0.0013 0.0061
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0119 0.0809 0.0796
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0013 0.0043
Trypanosoma brucei THT1 - hexose transporter, putative 0.001 0.0027 0.0126
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0008 0.0013 0.0061
Brugia malayi MAP kinase sur-1 0.0107 0.0721 0.1574
Loa Loa (eye worm) hypothetical protein 0.0018 0.0083 0.018
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0013 0.0181
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0013 0.0013
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0124 0.0272
Echinococcus granulosus histone lysine methyltransferase setb 0.0093 0.0624 0.0612
Mycobacterium ulcerans short-chain dehydrogenase 0.0008 0.0013 0.0043
Echinococcus granulosus dna polymerase eta 0.0019 0.0096 0.0083
Mycobacterium ulcerans short-chain dehydrogenase 0.0008 0.0013 0.0043
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0197 0.0353
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.008 0.1284
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0027 0.0035
Trypanosoma brucei sugar transporter, putative 0.001 0.0027 0.0126
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0197 0.0305
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0174 0.0276
Echinococcus multilocularis lamin 0.0027 0.015 0.0137
Leishmania major short chain dehydrogenase/reductase, putative 0.0008 0.0013 0.0061
Trichomonas vaginalis sugar transport protein, putative 0.001 0.0027 0.0035
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0008 0.0013 0.0061
Plasmodium falciparum basic transcription factor 3b, putative 0.0072 0.0475 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0093 0.0624 0.0624
Loa Loa (eye worm) intermediate filament protein 0.0027 0.015 0.0327
Echinococcus multilocularis transcription factor btf3 0.0072 0.0475 0.0462
Onchocerca volvulus 0.001 0.0027 0.0027
Plasmodium vivax steroid dehydrogenase, putative 0.0008 0.0013 0.0209
Schistosoma mansoni cpg binding protein 0.0031 0.0181 0.0181
Brugia malayi Sugar transporter family protein 0.001 0.0027 0.0059
Giardia lamblia Hexose transporter 0.001 0.0027 0.0043
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0024 0.0112
Schistosoma mansoni retinal dehydrogenase 0.0008 0.0013 0.0013
Trypanosoma brucei unspecified product 0.0013 0.0053 0.0247
Trypanosoma cruzi transcription factor btf3, putative 0.0072 0.0475 0.2226
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.001 0.0027 0.0027
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0087 0.0578 0.1854
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0051 0.024
Echinococcus granulosus pyruvate kinase 0.0034 0.0197 0.0184
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0117 0.0792 0.2553
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.001 0.0027 0.0014
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0384 0.5319
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0174 0.0268
Onchocerca volvulus 0.001 0.0027 0.0027
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0008 0.0013 0.0013
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0013 0.0051 0.3141
Onchocerca volvulus 0.001 0.0027 0.0027
Onchocerca volvulus 0.001 0.0027 0.0027
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0096 0.045
Loa Loa (eye worm) major facilitator superfamily transporter 0.001 0.0027 0.0059
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.005 0.0037
Echinococcus granulosus mitogen activated protein kinase 3 0.0107 0.0721 0.0709
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0197 0.0353
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0008 0.0013 0.0061
Schistosoma mansoni 6-phosphofructokinase 0.0112 0.0761 0.0761
Giardia lamblia Fructose-bisphosphate aldolase 0.0888 0.6316 1
Brugia malayi dehydrogenases, short chain protein 2 0.0008 0.0013 0.0028
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0041 0.0193
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0096 0.0209
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0027 0.0035
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0063 0.0406 0.1904
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0013 0.0013
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Onchocerca volvulus 0.001 0.0027 0.0027
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0013 0.0013
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0024 0.0112
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0013 0.0013
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0025 0.0135 0.0133
Schistosoma mansoni pyruvate kinase 0.0034 0.0197 0.0197
Echinococcus granulosus Solute carrier family 22 5 0.1035 0.7366 0.7362
Mycobacterium tuberculosis Conserved hypothetical protein 0.016 0.1103 0.3573
Leishmania major ATP-dependent phosphofructokinase 0.0112 0.0761 0.3567
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0013 0.0028
Mycobacterium leprae conserved hypothetical protein 0.0025 0.0135 0.0399
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0144 0.0987 0.4626
Entamoeba histolytica hypothetical protein 0.0025 0.0135 0.0193
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0117 0.0792 0.078
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0174 0.0268
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0096 0.0209
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0174 0.3666
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0015 0.0062 0.0864
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0013 0.0013
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0096 0.0313
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0051 0.024
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0107 0.0721 0.3383
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0011 0.0034 0.0034
Trypanosoma brucei protein kinase, putative 0.0107 0.0721 0.3383
Trypanosoma cruzi hexose transporter, putative 0.001 0.0027 0.0126
Trichomonas vaginalis glucose transporter, putative 0.001 0.0027 0.0035
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Plasmodium vivax hexose transporter 0.001 0.0027 0.0432
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Loa Loa (eye worm) hypothetical protein 0.0008 0.0013 0.0028
Brugia malayi Major Facilitator Superfamily protein 0.001 0.0027 0.0059
Trypanosoma brucei short-chain dehydrogenase, putative 0.0008 0.0013 0.0061
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0263 0.1232
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0013 0.0028
Loa Loa (eye worm) 6-phosphofructokinase 0.0112 0.0761 0.166
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0008 0.0013 0.0043
Trichomonas vaginalis myo-inositol transporter, putative 0.001 0.0027 0.0035
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0013 0.0028
Brugia malayi Sugar transporter family protein 0.001 0.0027 0.0059
Trypanosoma brucei transcription factor BTF3, putative 0.0072 0.0475 0.2226
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0008 0.0013 0.0061
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.0034 0.0021
Trypanosoma brucei glucose transporter 1E 0.001 0.0027 0.0126
Brugia malayi Retinol dehydrogenase 12 0.0008 0.0013 0.0028
Echinococcus granulosus dna polymerase kappa 0.0019 0.0096 0.0083
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Giardia lamblia Sgs1 DNA helicase, putative 0.0009 0.0022 0.0035
Entamoeba histolytica hypothetical protein 0.0072 0.0475 0.0732
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0008 0.0013 0.0061
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0097 0.0648 0.2081
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0089 0.0595 0.0583
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0009 0.0022 0.0463
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0008 0.0013 0.0061
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0008 0.0012 0.0012
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0013 0.0051 0.024
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0761 0.1198
Mycobacterium ulcerans 6-phosphofructokinase 0.0112 0.0761 0.2484
Mycobacterium ulcerans dehydrogenase/reductase 0.0008 0.0013 0.0043
Echinococcus multilocularis pyruvate kinase 0.0034 0.0197 0.0184
Trypanosoma cruzi hexose transporter, putative 0.001 0.0027 0.0126
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0115 0.0174
Loa Loa (eye worm) glutathione reductase 0.0038 0.0229 0.05
Trypanosoma brucei glucose transporter, putative 0.001 0.0027 0.0126
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0009 0.0022 0.0009
Leishmania major oxidoreductase-like protein 0.0008 0.0013 0.0061
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0013 0.0043
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.008 0.1112
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0888 0.6316 1
Schistosoma mansoni hypothetical protein 0.001 0.0027 0.0027
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0096 0.045
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0107 0.0721 0.3383
Schistosoma mansoni cpg binding protein 0.003 0.0169 0.0169
Schistosoma mansoni glucose transporter 0.001 0.0027 0.0027
Trypanosoma brucei glucose transporter, putative 0.001 0.0027 0.0126
Brugia malayi pyruvate kinase, muscle isozyme 0.0007 0.0007 0.0016
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0013 0.0051 0.024
Giardia lamblia Hypothetical protein 0.0008 0.0013 0.0021
Leishmania major pyruvate kinase 0.0034 0.0197 0.0925
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0197 0.043
Loa Loa (eye worm) hypothetical protein 0.0009 0.0022 0.0047
Trypanosoma brucei oxidoreductase-like protein 0.0008 0.0013 0.0061
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0005 0.000000000042566
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0008 0.0013 0.0061
Brugia malayi oxidoreductase 0.0008 0.0013 0.0028
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0115 0.025
Onchocerca volvulus 0.001 0.0027 0.0027
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.0761 0.1186
Mycobacterium ulcerans dehydrogenase 0.0008 0.0013 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0027 0.0035
Giardia lamblia Sugar-proton symporter 0.001 0.0027 0.0043
Brugia malayi beta-NAC-like protein 0.0072 0.0475 0.1036
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0013 0.0028
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0149 0.0697
Leishmania major quinonoid dihydropteridine reductase 0.0008 0.0013 0.0061
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0013 0.0051 0.024
Loa Loa (eye worm) 6-phosphofructokinase 0.0112 0.0761 0.166
Plasmodium falciparum steroid dehydrogenase, putative 0.0008 0.0013 0.0275
Echinococcus granulosus cpg binding protein 0.0031 0.0181 0.0169
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0025 0.0135 0.1868
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0008 0.0013 0.0275
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0013 0.0028
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0005 0.000000000042566
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0051 0.024
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0008 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0026 0.0146 0.0319
Toxoplasma gondii aldehyde dehydrogenase 0.0063 0.0406 0.5628
Echinococcus granulosus 6 phosphofructokinase 0.0112 0.0761 0.0749
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0059
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0096 0.0083
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0117 0.0792 0.1727
Leishmania major basic transcription factor 3a, putative 0.0072 0.0475 0.2226
Trypanosoma cruzi hexose transporter, putative 0.001 0.0027 0.0126
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0475 0.0744
Toxoplasma gondii sugar transporter ST2 0.001 0.0027 0.0374
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.001 0.0027 0.0014
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0112 0.0761 0.3567
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.001 0.0027 0.0088
Loa Loa (eye worm) pyruvate kinase 0.0007 0.0007 0.0016
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0304 0.2133 1
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0013 0.0013
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0013 0.0181
Trypanosoma cruzi hypothetical protein, conserved 0.0008 0.0013 0.0061
Loa Loa (eye worm) oxidoreductase 0.0008 0.0013 0.0028
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.015 0.0327
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0025 0.0135 0.5721
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0008 0.0013 0.0013
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0063 0.0406 0.0393
Echinococcus multilocularis solute carrier family 22 0.001 0.0027 0.0014
Echinococcus granulosus lamin 0.0027 0.015 0.0137
Loa Loa (eye worm) oxidoreductase 0.0008 0.0013 0.0028
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0107 0.0721 0.3383
Mycobacterium ulcerans oxidoreductase 0.0008 0.0013 0.0043
Leishmania major hypothetical protein, conserved 0.0008 0.0013 0.0061
Trypanosoma cruzi sugar transporter, putative 0.001 0.0027 0.0126
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0096 0.0209
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.001 0.0027 0.0568
Trypanosoma brucei short-chain dehydrogenase, putative 0.0008 0.0013 0.0061
Loa Loa (eye worm) hypothetical protein 0.0008 0.0013 0.0028
Echinococcus granulosus pyruvate kinase 0.0017 0.008 0.0067
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0119 0.0809 0.0809
Loa Loa (eye worm) dehydrogenase 0.0008 0.0013 0.0028
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0008 0.0013 0.0061
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0013 0.0051 0.0167
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0096 0.2012
Trypanosoma brucei trypanothione reductase 0.0038 0.0229 0.1076
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0008 0.0013 0.0013
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0406 0.1325
Echinococcus multilocularis pyruvate kinase 0.0017 0.008 0.0067
Loa Loa (eye worm) hypothetical protein 0.0027 0.015 0.0327
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0034 0.0197 0.0604
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0059
Loa Loa (eye worm) oxidoreductase 0.0008 0.0013 0.0028
Trypanosoma brucei glucose transporter, putative 0.001 0.0027 0.0126
Loa Loa (eye worm) hypothetical protein 0.0008 0.0013 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0475 0.0744
Trypanosoma cruzi hexose transporter 0.001 0.0027 0.0126
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0013 0.0028
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Trypanosoma brucei glucose transporter 2A 0.001 0.0027 0.0126
Echinococcus multilocularis pyruvate kinase 0.0034 0.0197 0.0184
Onchocerca volvulus 0.0093 0.0624 0.1174
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0646 0.4583 1
Echinococcus granulosus solute carrier family 22 0.001 0.0027 0.0014
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.015 0.0327
Mycobacterium ulcerans short-chain type oxidoreductase 0.0008 0.0013 0.0043
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0013 0.0028
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0406 0.0406
Leishmania major phosphopantetheinyl transferase-like protein 0.0025 0.0135 0.0632
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0013 0.0013
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0008 0.0013 0.0061
Loa Loa (eye worm) hypothetical protein 0.001 0.0027 0.0059
Brugia malayi Sugar transporter family protein 0.001 0.0027 0.0059
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0011 0.0034 0.0021
Trypanosoma brucei glucose transporter, putative 0.001 0.0027 0.0126
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0008 0.0013 0.0013
Giardia lamblia Pyruvate kinase 0.0017 0.008 0.0127
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0174 0.2413
Trichomonas vaginalis glutathione reductase, putative 0.0013 0.0051 0.0073
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0008 0.0013 0.0061
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0096 0.045
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0013 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0027 0.0035
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0096 0.045
Brugia malayi hypothetical protein 0.0017 0.0081 0.0176
Trypanosoma cruzi transcription factor btf3, putative 0.0072 0.0475 0.2226
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0888 0.6316 1
Trypanosoma brucei glucose transporter, putative 0.001 0.0027 0.0126
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0013 0.0043
Loa Loa (eye worm) hypothetical protein 0.0013 0.005 0.0109
Trypanosoma brucei THT1 - hexose transporter, putative 0.001 0.0027 0.0126
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0005 0.000000000042566
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0008 0.0013 0.0043
Mycobacterium ulcerans carveol-like dehydrogenase 0.0008 0.0013 0.0043
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0008 0.0013 0.0061
Schistosoma mansoni hypothetical protein 0.0169 0.117 0.117
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0022 0.0305
Trypanosoma brucei glucose transporter, putative 0.001 0.0027 0.0126
Echinococcus multilocularis thioredoxin glutathione reductase 0.0039 0.0233 0.022
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0406 0.1325
Plasmodium vivax sugar transporter, putative 0.001 0.0027 0.0432
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Echinococcus granulosus bloom syndrome protein 0.0022 0.0115 0.0102
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0013 0.0051 0.024
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0087 0.0578 0.1854
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0008 0.0013 0.0061
Loa Loa (eye worm) oxidoreductase 0.0008 0.0013 0.0028
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0013 0.0043
Brugia malayi F/Y-rich N-terminus family protein 0.0012 0.0046 0.0101
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0096 0.045
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0013 0.0013
Brugia malayi Pyruvate kinase, muscle isozyme 0.0034 0.0197 0.043
Trichomonas vaginalis CMGC family protein kinase 0.0107 0.0721 0.1135
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0008 0.0013 0.0181
Mycobacterium tuberculosis Probable oxidoreductase 0.0097 0.0648 0.2081
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0013 0.0043
Schistosoma mansoni DNA helicase recq1 0.0009 0.0022 0.0022
Schistosoma mansoni hypothetical protein 0.0012 0.0043 0.0043
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0053 0.0247
Trypanosoma cruzi trypanothione reductase, putative 0.0013 0.0051 0.024
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0096 0.045
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0013 0.0043
Mycobacterium ulcerans oxidoreductase 0.0008 0.0013 0.0043
Mycobacterium ulcerans ketoacyl reductase 0.0008 0.0013 0.0043
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0013 0.0051 0.0711
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0013 0.0043
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0013 0.0013
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0013 0.0051 0.024
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0013 0.0043
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0008 0.0013 0.0275
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0096 0.0131
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.001 0.0027 0.0014
Schistosoma mansoni lamin 0.0027 0.015 0.015
Leishmania major DNA polymerase kappa, putative 0.0019 0.0096 0.045
Entamoeba histolytica recQ family helicase, putative 0.0012 0.0041 0.0045
Plasmodium vivax pyruvate kinase, putative 0.0034 0.0197 0.3158
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0096 0.0144
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.001 0.0027 0.0014
Toxoplasma gondii thioredoxin reductase 0.0038 0.0229 0.318
Echinococcus granulosus pyruvate kinase 0.0017 0.008 0.0067
Brugia malayi Major Facilitator Superfamily protein 0.001 0.0027 0.0059
Echinococcus multilocularis L aminoadipate semialdehyde 0.0088 0.0589 0.0577
Onchocerca volvulus 0.0027 0.015 0.0263
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0013 0.0051 0.0821
Loa Loa (eye worm) hypothetical protein 0.0034 0.0197 0.043
Trypanosoma brucei short-chain dehydrogenase, putative 0.0008 0.0013 0.0061
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.0263 0.1232
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0013 0.0013
Leishmania major short chain dehydrogenase, putative 0.0008 0.0013 0.0061
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0263 0.1232
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0012 0.0043 0.003
Schistosoma mansoni hypothetical protein 0.0169 0.117 0.117
Echinococcus granulosus mixed lineage leukemia protein mll 0.0011 0.0034 0.0021
Echinococcus granulosus solute carrier family 22 0.001 0.0027 0.0014
Schistosoma mansoni pyruvate kinase 0.0017 0.008 0.008
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0149 0.206
Trichomonas vaginalis glucose transporter, putative 0.001 0.0027 0.0035
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0013 0.0051 0.024
Onchocerca volvulus 0.001 0.0027 0.0027
Schistosoma mansoni intermediate filament proteins 0.0027 0.015 0.015
Giardia lamblia Pyruvate kinase 0.0034 0.0197 0.0312
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0096 0.045
Toxoplasma gondii hypothetical protein 0.0049 0.0308 0.4267
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.0034 0.0021
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0008 0.0013 0.0028
Onchocerca volvulus 0.001 0.0027 0.0027
Brugia malayi Pyruvate kinase, M2 isozyme 0.0034 0.0197 0.043
Onchocerca volvulus 0.0027 0.015 0.0263
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0053 0.0247
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0096 0.045
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0013 0.0047 0.0034
Loa Loa (eye worm) hypothetical protein 0.0008 0.0013 0.0028
Leishmania major quinonoid dihydropteridine reductase 0.0008 0.0013 0.0061
Brugia malayi major facilitator superfamily protein 0.001 0.0027 0.0059
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0013 0.0181
Onchocerca volvulus 0.001 0.0027 0.0027
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0013 0.0043
Brugia malayi dehydrogenases, short chain protein 9 0.0008 0.0013 0.0028
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0096 0.045
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0117 0.0792 0.0792
Echinococcus granulosus lamin dm0 0.0027 0.015 0.0137
Trypanosoma cruzi glucose transporter, putative 0.001 0.0027 0.0126
Trichomonas vaginalis sugar transporter, putative 0.001 0.0027 0.0035
Schistosoma mansoni serine/threonine protein kinase 0.0107 0.0721 0.0721
Schistosoma mansoni DNA polymerase eta 0.0019 0.0096 0.0096
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0096 0.045
Toxoplasma gondii carbonyl reductase 1, putative 0.0008 0.0013 0.0181
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0096 0.0096
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0174 0.2413
Leishmania major 3-keto-dihydrosphingosine reductase 0.0008 0.0013 0.0061
Trypanosoma brucei unspecified product 0.0013 0.0053 0.0247
Trypanosoma cruzi cytochrome P450, putative 0.0013 0.0048 0.0224
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0097 0.0648 0.2081
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.001 0.003 0.0065
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0144 0.0987 0.4626
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0088 0.0589 0.0589
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0174 0.2787
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0087 0.0578 0.1854
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0013 0.0013
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.001 0.0027 0.0088
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0025 0.0135 1
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0013 0.0013
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0008 0.0013 0.0043
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0087 0.0578 0.1854
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0053 0.0247
Brugia malayi 6-phosphofructokinase 0.0112 0.0761 0.166
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0144 0.0987 0.4626
Mycobacterium ulcerans short chain dehydrogenase 0.0008 0.0013 0.0043
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0109 0.0736 0.1605
Leishmania major dehydrogenase-like protein 0.0008 0.0013 0.0061

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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