Detailed information for compound 881957

Basic information

Technical information
  • TDR Targets ID: 881957
  • Name: 2-(4-methoxyquinoline-2-carbonyl)-N-prop-2-en ylpyrazolidine-1-carboxamide
  • MW: 340.376 | Formula: C18H20N4O3
  • H donors: 1 H acceptors: 3 LogP: 2.25 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: C=CCNC(=O)N1CCCN1C(=O)c1cc(OC)c2c(n1)cccc2
  • InChi: 1S/C18H20N4O3/c1-3-9-19-18(24)22-11-6-10-21(22)17(23)15-12-16(25-2)13-7-4-5-8-14(13)20-15/h3-5,7-8,12H,1,6,9-11H2,2H3,(H,19,24)
  • InChiKey: GGTQHBDDDVWFAR-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-allyl-2-(4-methoxyquinoline-2-carbonyl)pyrazolidine-1-carboxamide
  • N-allyl-2-[(4-methoxy-2-quinolyl)-oxomethyl]-1-pyrazolidinecarboxamide
  • 2-(4-methoxyquinolin-2-yl)carbonyl-N-prop-2-enyl-pyrazolidine-1-carboxamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium falciparum LCCL domain-containing protein 0.0051 0.0023 0.055
Onchocerca volvulus 0.003 0.0003 0.0044
Toxoplasma gondii subtilisin SUB1 0.0467 0.0415 1
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0084 0.0053 0.0787
Echinococcus granulosus methyltransferase protein 5 0.0088 0.0057 0.0057
Echinococcus granulosus Coagulation factor 5 8 type C terminal 0.0051 0.0023 0.0023
Echinococcus multilocularis integrin alpha ps 0.0249 0.0209 0.0262
Schistosoma mansoni hypothetical protein 0.0088 0.0057 0.0057
Entamoeba histolytica NAD-dependent deacetylase 1, putative 0.0111 0.0079 0.1154
Loa Loa (eye worm) hypothetical protein 0.0097 0.0065 0.0065
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0642 0.058 0.058
Loa Loa (eye worm) hypothetical protein 0.0036 0.0009 0.0009
Plasmodium vivax subtilisin-like protease 1 0.0467 0.0415 1
Echinococcus granulosus integrin alpha ps 0.0249 0.0209 0.0209
Mycobacterium ulcerans membrane-anchored mycosin MycP3 0.0467 0.0415 1
Onchocerca volvulus 0.0105 0.0074 0.107
Onchocerca volvulus 0.0036 0.0008 0.0113
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0079 0.0049 0.0049
Toxoplasma gondii hypothetical protein 0.01 0.0069 0.166
Giardia lamblia Neurogenic locus Notch protein precursor 0.01 0.0069 0.0107
Loa Loa (eye worm) hypothetical protein 0.0038 0.001 0.001
Loa Loa (eye worm) integrin alpha pat-2 0.1297 0.1199 0.1199
Brugia malayi hypothetical protein 0.003 0.0003 0.0003
Loa Loa (eye worm) transcriptional regulator 0.0111 0.0079 0.0079
Schistosoma mansoni c4b-binding protein beta chain 0.0036 0.0008 0.0008
Echinococcus granulosus nmda type glutamate receptor 0.0112 0.008 0.008
Schistosoma mansoni glutamate receptor AMPA 0.0031 0.0004 0.0004
Trichomonas vaginalis hypothetical protein 0.0051 0.0023 0.0037
Schistosoma mansoni chromatin regulatory protein sir2 0.075 0.0682 0.0682
Echinococcus granulosus cubilin 0.003 0.0003 0.0003
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0467 0.0415 0.068
Echinococcus granulosus Furin 1 0.258 0.241 0.241
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0142 0.0108 0.2613
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0686 0.0621 0.0776
Mycobacterium ulcerans Type I modular polyketide synthase 0.0079 0.0049 0.0665
Onchocerca volvulus 0.003 0.0003 0.0044
Brugia malayi Angiotensin-converting enzyme family protein 0.0639 0.0578 0.0578
Schistosoma mansoni protein kinase 0.0252 0.0213 0.0213
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0039 0.0011 0.0011
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.258 0.241 0.3949
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0119 0.0087 0.1985
Loa Loa (eye worm) TK/EGFR protein kinase 0.0657 0.0594 0.0594
Toxoplasma gondii subtilisin SUB7 0.0467 0.0415 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0008 0.0008
Leishmania major arginine N-methyltransferase, type III, putative;with=GeneDB:Tb927.7.5490 0.0088 0.0057 0.0791
Loa Loa (eye worm) hypothetical protein 0.0039 0.0011 0.0011
Brugia malayi Eukaryotic aspartyl protease family protein 0.0039 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0053 0.0024 0.0024
Onchocerca volvulus 0.0036 0.0008 0.0113
Toxoplasma gondii aspartyl protease ASP3 0.0039 0.0011 0.026
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0031 0.0004 0.0092
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0111 0.0079 0.0129
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0023 0.0037
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0111 0.0079 0.0079
Leishmania major NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe 0.0111 0.0079 0.1104
Schistosoma mansoni hypothetical protein 0.003 0.0003 0.0003
Plasmodium falciparum subtilisin-like protease 1 0.0467 0.0415 1
Trypanosoma cruzi UDP-galactopyranose mutase 0.0142 0.0108 0.1536
Schistosoma mansoni hypothetical protein 0.0097 0.0065 0.0065
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0088 0.0057 0.0094
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0044 0.0016 0.0016
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.075 0.0682 0.0682
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0615 0.0555 0.0555
Echinococcus multilocularis integrin alpha 3 0.0696 0.0631 0.0789
Loa Loa (eye worm) hypothetical protein 0.003 0.0003 0.0003
Loa Loa (eye worm) lectin C-type domain-containing protein 0.003 0.0003 0.0003
Onchocerca volvulus 0.0039 0.0011 0.0157
Brugia malayi Protein kinase domain containing protein 0.0051 0.0023 0.0023
Brugia malayi celfurPC protein 0.8508 0.8005 0.8005
Echinococcus granulosus protein arginine N methyltransferase 8 0.0157 0.0122 0.0122
Brugia malayi Glutamate receptor 2 precursor 0.0031 0.0004 0.0004
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0079 0.0049 0.1054
Giardia lamblia hypothetical protein 0.01 0.0069 0.0107
Giardia lamblia Tenascin-X 0.01 0.0069 0.0107
Onchocerca volvulus Deterin homolog 0.0105 0.0074 0.107
Echinococcus granulosus Tolloid protein 1 0.003 0.0003 0.0003
Entamoeba histolytica arginine N-methyltransferase 1, putative 0.0088 0.0057 0.0843
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0245 0.0205 0.2965
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0039 0.0011 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0467 0.0415 0.068
Loa Loa (eye worm) hypothetical protein 0.0062 0.0033 0.0033
Toxoplasma gondii rhoptry neck protein RON9 0.0036 0.0008 0.0188
Brugia malayi Protein kinase domain containing protein 0.0097 0.0065 0.0065
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0041 0.0013 0.0318
Toxoplasma gondii F5/8 type C domain-containing protein 0.0051 0.0023 0.055
Plasmodium vivax subtilisin-like protease 2, putative 0.0467 0.0415 1
Loa Loa (eye worm) zinc metalloproteinase toh-2 0.003 0.0003 0.0003
Brugia malayi CUB domain containing protein 0.003 0.0003 0.0003
Entamoeba histolytica SWIRM domain protein 0.0059 0.003 0.0441
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.6492 0.6102 0.6102
Loa Loa (eye worm) hypothetical protein 0.0036 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.01 0.0069 0.0069
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0036 0.0008 0.0008
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0236 0.0197 0.0197
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0142 0.0108 0.0108
Echinococcus multilocularis SWI:SNF complex subunit SMARCC2 0.0059 0.003 0.0038
Brugia malayi Sushi domain 0.0036 0.0008 0.0008
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0097 0.0066 0.0066
Trypanosoma brucei Silent information regulator 2 related protein 1 0.075 0.0682 1
Plasmodium falciparum calcium-dependent protein kinase 1 0.0031 0.0004 0.0092
Echinococcus granulosus c4b binding protein beta chain 0.0036 0.0008 0.0008
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0142 0.0108 0.2189
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0055 0.0026 0.0026
Echinococcus granulosus c-Jun N-terminal kinases 0.0236 0.0197 0.0197
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.258 0.241 0.3949
Echinococcus granulosus protein arginine methyltransferase 0.0157 0.0122 0.0122
Mycobacterium ulcerans polyketide synthase Pks13 0.0119 0.0087 0.1636
Schistosoma mansoni hypothetical protein 0.003 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0023 0.0037
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0039 0.0011 0.0011
Echinococcus granulosus CUB 0.003 0.0003 0.0003
Echinococcus granulosus MAM 0.0097 0.0065 0.0065
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0639 0.0578 0.0578
Brugia malayi CUB domain containing protein 0.003 0.0003 0.0003
Echinococcus granulosus discoidin domain receptor 0.0051 0.0023 0.0023
Brugia malayi zinc metalloproteinase toh-2 precursor 0.003 0.0003 0.0003
Brugia malayi Zinc metalloproteinase toh-2 precursor 0.003 0.0003 0.0003
Echinococcus granulosus adam 0.0219 0.0181 0.0181
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0467 0.0415 0.068
Plasmodium falciparum calcium-dependent protein kinase 2 0.0031 0.0004 0.0092
Schistosoma mansoni chromatin regulatory protein sir2 0.0111 0.0079 0.0079
Echinococcus multilocularis Coagulation factor 5 8 type, C terminal 0.0051 0.0023 0.0029
Trichomonas vaginalis hypothetical protein 0.2113 0.1969 0.3226
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0059 0.003 0.0591
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0111 0.0079 0.0129
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0467 0.0415 0.068
Echinococcus multilocularis protein jagged 2 0.01 0.0069 0.0086
Brugia malayi Nematode astacin protease protein 30 0.003 0.0003 0.0003
Mycobacterium tuberculosis Probable thioesterase TesA 0.0068 0.0038 0.0807
Brugia malayi Disintegrin family protein 0.0038 0.001 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.003 0.0049
Plasmodium falciparum plasmepsin VIII, putative 0.0039 0.0011 0.026
Toxoplasma gondii histone arginine methyltransferase PRMT1 0.0157 0.0122 0.2941
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0039 0.0011 0.0011
Plasmodium falciparum transcriptional regulatory protein sir2b 0.0111 0.0079 0.1896
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0467 0.0415 0.0415
Mycobacterium leprae Polyketide synthase Pks13 0.0119 0.0087 0.1636
Loa Loa (eye worm) integrin beta-2 0.3824 0.3584 0.3584
Schistosoma mansoni tyrosine kinase 0.0657 0.0594 0.0594
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.2113 0.1969 0.3226
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0111 0.0079 0.0129
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0044 0.0016 0.0016
Plasmodium falciparum plasmepsin X 0.0039 0.0011 0.026
Schistosoma mansoni apoptosis regulator bax 0.0055 0.0026 0.0026
Onchocerca volvulus 0.0036 0.0008 0.0113
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0023 0.0037
Plasmodium falciparum plasmepsin VI 0.0039 0.0011 0.026
Plasmodium falciparum subtilisin-like protease 2 0.0467 0.0415 1
Loa Loa (eye worm) hypothetical protein 0.0134 0.0101 0.0101
Echinococcus multilocularis glutamate receptor 2 0.0031 0.0004 0.0005
Entamoeba histolytica protein kinase, putative 0.0033 0.0005 0.0076
Loa Loa (eye worm) hypothetical protein 0.0105 0.0074 0.0074
Loa Loa (eye worm) CUB domain-containing protein 0.003 0.0003 0.0003
Schistosoma mansoni ATP-binding cassette transporter 0.0031 0.0004 0.0004
Brugia malayi angiogenesis inhibito 0.0053 0.0024 0.0024
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0039 0.0011 0.0011
Echinococcus multilocularis C type lectin domian containing protein 0.0036 0.0008 0.001
Trichomonas vaginalis CAMK family protein kinase 0.0031 0.0004 0.0006
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0111 0.0079 0.0129
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0023 0.0037
Onchocerca volvulus 0.0032 0.0004 0.0062
Echinococcus granulosus furin 1.0621 1 1
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0252 0.0213 0.0213
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0142 0.0108 0.2189
Mycobacterium ulcerans polyketide synthase 0.0084 0.0053 0.0787
Echinococcus granulosus tissue type plasminogen activator 0.0032 0.0004 0.0004
Mycobacterium ulcerans Type I modular polyketide synthase 0.0079 0.0049 0.0665
Schistosoma mansoni hypothetical protein 0.0051 0.0023 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.2113 0.1969 0.3226
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0047 0.0019 0.0019
Loa Loa (eye worm) glutamate receptor 2 0.0031 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0051 0.0023 0.0023
Toxoplasma gondii aspartyl protease ASP5 0.0397 0.0349 0.8405
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0039 0.0011 0.0011
Loa Loa (eye worm) proprotein convertase 2 0.258 0.241 0.241
Toxoplasma gondii histone deacetylase SIR2-like 0.0111 0.0079 0.1896
Echinococcus multilocularis discoidin domain containing receptor 2 0.0051 0.0023 0.0029
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0467 0.0415 0.068
Mycobacterium ulcerans dehydrogenase 0.0142 0.0108 0.2189
Onchocerca volvulus 0.0036 0.0008 0.0113
Echinococcus multilocularis Tolloid protein 1 0.003 0.0003 0.0004
Brugia malayi CUB domain containing protein 0.003 0.0003 0.0003
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.075 0.0682 0.1118
Echinococcus multilocularis Furin 1 0.258 0.241 0.301
Schistosoma mansoni neuropilin (nrp) and tolloid (tll)-like 0.003 0.0003 0.0003
Echinococcus multilocularis protein arginine N methyltransferase 8 0.0157 0.0122 0.0152
Echinococcus multilocularis protein kinase c epsilon type 0.0097 0.0066 0.0083
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0031 0.0004 0.0005
Echinococcus multilocularis integrin beta 2 0.2827 0.2642 0.3301
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0467 0.0415 0.068
Toxoplasma gondii subtilisin SUB8 0.0467 0.0415 1
Brugia malayi Protein arginine N-methyltransferase 0.0088 0.0057 0.0057
Schistosoma mansoni dihydroceramide desaturase 0.0038 0.001 0.001
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0031 0.0004 0.0092
Toxoplasma gondii aspartyl protease ASP1 0.0039 0.0011 0.026
Echinococcus granulosus disintegrin and metalloproteinase 0.0038 0.001 0.001
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0467 0.0415 0.068
Mycobacterium ulcerans thioesterase TesA 0.0068 0.0038 0.0406
Echinococcus granulosus SWI:SNF complex subunit SMARCC2 0.0059 0.003 0.003
Entamoeba histolytica arginine N-methyltransferase protein, putative 0.0245 0.0205 0.3009
Brugia malayi ADAM-TS Spacer 1 family protein 0.0053 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.003 0.0003 0.0003
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0091 0.006 0.006
Entamoeba histolytica hypothetical protein, conserved 0.0111 0.0079 0.1154
Loa Loa (eye worm) hypothetical protein 0.0699 0.0634 0.0634
Giardia lamblia High cysteine membrane protein Group 2 0.3912 0.3667 1
Entamoeba histolytica hypothetical protein 0.0059 0.003 0.0441
Loa Loa (eye worm) hypothetical protein 0.0039 0.0011 0.0011
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0031 0.0004 0.0005
Trypanosoma cruzi serine peptidase, clan SB, family S8-like protein 0.0467 0.0415 0.6059
Brugia malayi Subtilase family protein 0.0467 0.0415 0.0415
Plasmodium vivax hypothetical protein, conserved 0.0142 0.0108 0.2613
Brugia malayi transcriptional regulator, Sir2 family protein 0.0111 0.0079 0.0079
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0467 0.0415 0.068
Echinococcus multilocularis protoporphyrinogen oxidase 0.0142 0.0108 0.0135
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.075 0.0682 0.1118
Plasmodium vivax hypothetical protein, conserved 0.0142 0.0108 0.2613
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.0497 0.0444 0.6485
Loa Loa (eye worm) hypothetical protein 0.0245 0.0205 0.0205
Schistosoma mansoni discoidin domain receptor 0.0051 0.0023 0.0023
Plasmodium falciparum plasmepsin III 0.0039 0.0011 0.026
Mycobacterium tuberculosis Possible arabinofuranosyltransferase AftD 0.0051 0.0023 0.0425
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0157 0.0122 0.0122
Plasmodium falciparum plasmepsin II 0.0039 0.0011 0.026
Giardia lamblia Tenascin-like 0.01 0.0069 0.0107
Schistosoma mansoni btb and poz domain-containing protein 0.0051 0.0023 0.0023
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0036 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.003 0.0003 0.0003
Schistosoma mansoni glutamate receptor kainate 0.0031 0.0004 0.0004
Plasmodium falciparum protein arginine N-methyltransferase 1 0.0157 0.0122 0.2941
Schistosoma mansoni hypothetical protein 0.0031 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0142 0.0108 0.0108
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0039 0.0011 0.026
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0084 0.0053 0.1171
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0111 0.0079 0.0079
Loa Loa (eye worm) sirtuin 4 0.0111 0.0079 0.0079
Loa Loa (eye worm) aspartyl protease 6 0.0039 0.0011 0.0011
Brugia malayi Carm1-pending protein 0.0088 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0053 0.0024 0.0024
Echinococcus granulosus adam 17 protease 0.0038 0.001 0.001
Echinococcus multilocularis CUB 0.003 0.0003 0.0004
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0111 0.0079 0.1104
Trichomonas vaginalis conserved hypothetical protein 0.0467 0.0415 0.068
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0079 0.0049 0.0665
Schistosoma mansoni hypothetical protein 0.003 0.0003 0.0003
Onchocerca volvulus 0.0467 0.0415 0.6011
Echinococcus granulosus discoidin domain containing receptor 2 0.0051 0.0023 0.0023
Echinococcus granulosus integrin alpha 3 0.0696 0.0631 0.0631
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0157 0.0122 0.0122
Schistosoma mansoni chromatin regulatory protein sir2 0.0111 0.0079 0.0079
Trypanosoma brucei subtilisin peptidase 0.0467 0.0415 0.6061
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.0467 0.0415 0.0415
Onchocerca volvulus 0.0142 0.0108 0.157
Brugia malayi AMP-binding enzyme family protein 0.0076 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.003 0.0003 0.0003
Brugia malayi Integrin alpha pat-2 precursor 0.0967 0.0887 0.0887
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0036 0.0009 0.0009
Echinococcus granulosus fibrillin 2 0.01 0.0069 0.0069
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.258 0.241 0.3949
Brugia malayi ADAMTS-like protease 0.0053 0.0024 0.0024
Echinococcus multilocularis neuropilin (nrp) and tolloid (tll) 0.003 0.0003 0.0004
Echinococcus multilocularis growth factor receptor bound protein 2 0.0132 0.0099 0.0124
Plasmodium falciparum apical sushi protein 0.0036 0.0008 0.0188
Brugia malayi SWIRM domain containing protein 0.0759 0.069 0.069
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) 0.0467 0.0415 1
Onchocerca volvulus 0.0148 0.0114 0.1655
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0079 0.0049 0.1063
Leishmania major hypothetical protein, conserved 0.0032 0.0004 0.0006
Schistosoma mansoni neuropilin (nrp) and tolloid (tll)-like 0.003 0.0003 0.0003
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0142 0.0108 0.2189
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0004 0.0005
Schistosoma mansoni integrin alpha 0.0967 0.0887 0.0887
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0132 0.0099 0.0099
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) 0.0467 0.0415 1
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.003 0.0049
Onchocerca volvulus 0.0036 0.0008 0.0113
Schistosoma mansoni glutamate receptor NMDA 0.0047 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0051 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0031 0.0004 0.0004
Echinococcus granulosus cubilin 0.003 0.0003 0.0003
Mycobacterium ulcerans NAD-dependent deacetylase 0.0111 0.0079 0.1432
Toxoplasma gondii subtilisin SUB5 0.0467 0.0415 1
Echinococcus granulosus discoidin domain containing receptor 2 0.0051 0.0023 0.0023
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0467 0.0415 0.068
Leishmania major sir2-family protein-like protein 0.0111 0.0079 0.1104
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0076 0.0046 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.2113 0.1969 0.3226
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0039 0.0011 0.0011
Mycobacterium ulcerans monoamine oxidase 0.0142 0.0108 0.2189
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.2113 0.1969 0.3226
Schistosoma mansoni protein kinase 0.0252 0.0213 0.0213
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0111 0.0079 0.0129
Chlamydia trachomatis protoporphyrinogen oxidase 0.0142 0.0108 1
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.075 0.0682 0.0852
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0467 0.0415 0.068
Brugia malayi CUB domain containing protein 0.003 0.0003 0.0003
Echinococcus multilocularis protein will die slowly 0.0148 0.0114 0.0143
Echinococcus granulosus membrane bound transcription factor site 1 0.0467 0.0415 0.0415
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.008 0.005 0.0704
Trichomonas vaginalis hypothetical protein 0.01 0.0069 0.0113
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.258 0.241 0.3949
Loa Loa (eye worm) hypothetical protein 0.0105 0.0074 0.0074
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0039 0.0011 0.026
Echinococcus granulosus epidermal growth factor receptor 0.0657 0.0594 0.0594
Loa Loa (eye worm) transcriptional regulator 0.075 0.0682 0.0682
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0111 0.0079 0.0129
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.258 0.241 0.3949
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0032 0.0004 0.0103
Schistosoma mansoni integrin alpha-ps 0.052 0.0465 0.0465
Loa Loa (eye worm) hypothetical protein 0.0043 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0036 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.003 0.0003 0.0003
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0031 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0097 0.0065 0.0065
Echinococcus multilocularis integrin alpha ps 0.0582 0.0523 0.0654
Brugia malayi hypothetical protein 0.0036 0.0008 0.0008
Echinococcus granulosus serine:threonine protein kinase N2 0.008 0.0049 0.0049
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0111 0.0079 0.0129
Brugia malayi transcriptional regulator, Sir2 family protein 0.075 0.0682 0.0682
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.258 0.241 0.3949
Mycobacterium ulcerans proline rich membrane-anchored mycosin MycP5 0.0467 0.0415 1
Mycobacterium ulcerans Type I modular polyketide synthase 0.0079 0.0049 0.0665
Plasmodium vivax aspartyl proteinase, putative 0.0039 0.0011 0.026
Onchocerca volvulus 0.0036 0.0008 0.0113
Echinococcus multilocularis cubilin 0.003 0.0003 0.0004
Toxoplasma gondii histone lysine-specific demethylase 0.0142 0.0108 0.2613
Schistosoma mansoni cathepsin D (A01 family) 0.0039 0.0011 0.0011
Brugia malayi Probable ATP-dependent helicase DHX35 0.0034 0.0006 0.0006
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0031 0.0004 0.0004
Plasmodium vivax LCCL domain-containing protein 0.0051 0.0023 0.055
Giardia lamblia High cysteine protein 0.01 0.0069 0.0107
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0055 0.0026 0.0032
Brugia malayi hypothetical protein 0.0036 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.01 0.0069 0.0069
Brugia malayi hypothetical protein 0.0036 0.0008 0.0008
Echinococcus granulosus neuroendocrine convertase 2 0.6709 0.6307 0.6307
Trichomonas vaginalis conserved hypothetical protein 0.2113 0.1969 0.3226
Loa Loa (eye worm) subtilase 0.0467 0.0415 0.0415
Trichomonas vaginalis conserved hypothetical protein 0.2113 0.1969 0.3226
Toxoplasma gondii subtilisin SUB11 0.0467 0.0415 1
Brugia malayi transcriptional regulator, Sir2 family protein 0.0111 0.0079 0.0079
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0111 0.0079 0.1098
Onchocerca volvulus Putative cubilin 0.004 0.0012 0.0169
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0039 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0111 0.0079 0.0079
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0111 0.0079 0.0129
Schistosoma mansoni amine oxidase 0.0142 0.0108 0.0108
Leishmania major arginine N-methyltransferase, type I 0.0088 0.0057 0.0791
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0142 0.0108 0.2613
Brugia malayi pregnancy-associated plasma protein-A 0.0036 0.0008 0.0008
Plasmodium vivax plasmepsin V, putative 0.0436 0.0385 0.9286
Brugia malayi astacin protease protein 30 0.003 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0055 0.0026 0.0026
Plasmodium vivax subtilisin-like serine protease, putative 0.0467 0.0415 1
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0252 0.0213 0.0265
Leishmania major silent information regulator 2, putative 0.075 0.0682 1
Echinococcus granulosus protein will die slowly 0.0148 0.0114 0.0114
Schistosoma mansoni dock 0.0051 0.0023 0.0023
Trypanosoma cruzi arginine N-methyltransferase, type I 0.0088 0.0057 0.0785
Toxoplasma gondii SWIRM domain-containing protein 0.0059 0.003 0.0726
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0031 0.0004 0.0092
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0023 0.0037
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0467 0.0415 0.068
Brugia malayi Nematode astacin protease protein 30 0.003 0.0003 0.0003
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0084 0.0053 0.0787
Loa Loa (eye worm) protein arginine N-methyltransferase 0.0088 0.0057 0.0057
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0047 0.0019 0.0024
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0079 0.0049 0.0665
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.075 0.0682 1
Plasmodium falciparum calcium-dependent protein kinase 5 0.0031 0.0004 0.0092
Trichomonas vaginalis conserved hypothetical protein 0.0467 0.0415 0.068
Onchocerca volvulus Fatty acid synthase homolog 0.0147 0.0113 0.1639
Loa Loa (eye worm) hypothetical protein 0.0201 0.0164 0.0164
Toxoplasma gondii F5/8 type C domain-containing protein 0.0051 0.0023 0.055
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0699 0.0634 0.0634
Toxoplasma gondii F5/8 type C domain-containing protein 0.0051 0.0023 0.055
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0003 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.2113 0.1969 0.3226
Mycobacterium tuberculosis Conserved hypothetical protein 0.0142 0.0108 0.2515
Schistosoma mansoni protein kinase 0.0252 0.0213 0.0213
Echinococcus granulosus glutamate receptor subunit protein glur 0.0031 0.0004 0.0004
Mycobacterium ulcerans oxidoreductase 0.0142 0.0108 0.2189
Echinococcus multilocularis fibrillin 1 0.0103 0.0071 0.0089
Onchocerca volvulus 0.0759 0.069 1
Trichomonas vaginalis conserved hypothetical protein 0.2113 0.1969 0.3226
Onchocerca volvulus 0.0076 0.0046 0.067
Plasmodium vivax calcium-dependent protein kinase, putative 0.0031 0.0004 0.0092
Brugia malayi neuroendocrine convertase 1 precursor 0.6709 0.6307 0.6307
Loa Loa (eye worm) endoprotease bli-4 1.0621 1 1
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.2113 0.1969 0.3226
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0111 0.0079 0.0098
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0236 0.0197 0.0246
Loa Loa (eye worm) hypothetical protein 0.003 0.0003 0.0003
Brugia malayi Cam kinase protein 1 0.0031 0.0004 0.0004
Entamoeba histolytica SWIRM domain protein 0.0059 0.003 0.0441
Toxoplasma gondii subtilisin SUB2 0.0467 0.0415 1
Echinococcus multilocularis chromatin regulatory protein sir2 0.075 0.0682 0.0852
Onchocerca volvulus 0.0036 0.0008 0.0113
Brugia malayi Kringle domain containing protein 0.0032 0.0004 0.0004
Onchocerca volvulus 0.0039 0.0011 0.0157
Onchocerca volvulus 0.0036 0.0008 0.0113
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0467 0.0415 0.0415
Mycobacterium ulcerans Sir2-like regulatory protein 0.0111 0.0079 0.1432
Loa Loa (eye worm) apoptosis regulator protein 0.0055 0.0026 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0023 0.0037
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.075 0.0682 1
Brugia malayi aspartic protease BmAsp-2, identical 0.0039 0.0011 0.0011
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0063 0.0034 0.0281
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0157 0.0122 0.02
Mycobacterium leprae Possible secreted protease 0.0467 0.0415 1
Onchocerca volvulus 0.0036 0.0009 0.0126
Loa Loa (eye worm) WD40 repeat protein 0.0148 0.0114 0.0114
Echinococcus granulosus neuropilin nrp and tolloid tll 0.003 0.0003 0.0003
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0111 0.0079 0.0098
Echinococcus multilocularis serine:threonine protein kinase N2 0.0089 0.0058 0.0073
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0079 0.0049 0.0665
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0467 0.0415 0.068
Schistosoma mansoni glutamate receptor AMPA 0.0031 0.0004 0.0004
Echinococcus multilocularis disintegrin and metalloproteinase 0.0038 0.001 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.2113 0.1969 0.3226
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0467 0.0415 0.068
Schistosoma mansoni hypothetical protein 0.0249 0.0209 0.0209
Plasmodium falciparum plasmepsin IV 0.0039 0.0011 0.026
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0066 0.0066
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0467 0.0415 0.068
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0265 0.0224 0.028
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0084 0.0053 0.1171
Brugia malayi aspartic protease BmAsp-1, identical 0.0039 0.0011 0.0011
Loa Loa (eye worm) Carm1-pending protein 0.0088 0.0057 0.0057
Trypanosoma cruzi arginine N-methyltransferase, type III 0.0088 0.0057 0.0785
Plasmodium vivax apical sushi protein, putative 0.0036 0.0008 0.0188
Schistosoma mansoni growth factor receptor-bound protein 0.0132 0.0099 0.0099
Trypanosoma cruzi subtilisin peptidase 0.0467 0.0415 0.6059
Loa Loa (eye worm) hypothetical protein 0.0333 0.0288 0.0288
Brugia malayi Pepsin A precursor 0.0039 0.0011 0.0011
Giardia lamblia Tenascin precursor 0.01 0.0069 0.0107
Brugia malayi Protein kinase domain containing protein 0.0032 0.0004 0.0004
Echinococcus multilocularis protein arginine methyltransferase 0.0157 0.0122 0.0152
Loa Loa (eye worm) hypothetical protein 0.0036 0.0008 0.0008
Brugia malayi Furin-like cysteine rich region family protein 0.0657 0.0594 0.0594
Plasmodium vivax aspartyl protease, putative 0.0039 0.0011 0.026
Loa Loa (eye worm) hypothetical protein 0.003 0.0003 0.0003
Echinococcus multilocularis membrane bound transcription factor site 1 0.0467 0.0415 0.0518
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0047 0.0019 0.0019
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0111 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.003 0.0003 0.0003
Onchocerca volvulus 0.0178 0.0142 0.2059
Brugia malayi Kelch motif family protein 0.0615 0.0555 0.0555
Loa Loa (eye worm) DPY-31 protein 0.003 0.0003 0.0003
Schistosoma mansoni glutamate receptor kainate 0.0031 0.0004 0.0004
Onchocerca volvulus 0.0036 0.0008 0.0113
Schistosoma mansoni glutamate receptor kainate 0.0031 0.0004 0.0004
Plasmodium falciparum plasmepsin VII 0.0039 0.0011 0.026
Loa Loa (eye worm) hypothetical protein 0.4129 0.3872 0.3872
Plasmodium vivax hypothetical protein, conserved 0.0111 0.0079 0.1896
Loa Loa (eye worm) hypothetical protein 0.0447 0.0396 0.0396
Echinococcus granulosus calcium dependent protein kinase 0.003 0.0003 0.0003
Trichomonas vaginalis beta-hexosaminidase B, putative 0.0051 0.0023 0.0037
Onchocerca volvulus 0.0051 0.0023 0.0331
Schistosoma mansoni hypothetical protein 0.0148 0.0114 0.0114
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0031 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0699 0.0634 0.0634
Loa Loa (eye worm) hypothetical protein 0.003 0.0003 0.0003
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0031 0.0004 0.0004
Echinococcus granulosus C type lectin domian containing protein 0.0036 0.0008 0.0008
Brugia malayi hypothetical protein 0.0119 0.0087 0.0087
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0105 0.0074 0.0074
Echinococcus multilocularis NMDA receptor 0.0031 0.0004 0.0005
Echinococcus multilocularis c4b binding protein beta chain 0.0036 0.0008 0.001
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0079 0.0049 0.1063
Loa Loa (eye worm) hypothetical protein 0.0467 0.0415 0.0415
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0063 0.0034 0.0281
Giardia lamblia Tenascin-37 0.01 0.0069 0.0107
Leishmania major arginine N-methyltransferase-like protein 0.0157 0.0122 0.1743
Plasmodium vivax protein arginine N-methyltransferase 1, putative 0.0157 0.0122 0.2941
Loa Loa (eye worm) fatty acid synthase 0.0081 0.005 0.005
Plasmodium vivax NAD-dependent deacetylase, putative 0.0111 0.0079 0.1896
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.0467 0.0415 0.0415
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0039 0.0011 0.0018
Toxoplasma gondii subtilisin SUB9 0.0467 0.0415 1
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.003 0.0003 0.0003
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0079 0.0049 0.1054
Echinococcus multilocularis inhibitor of apoptosis protein 0.0105 0.0074 0.0092
Echinococcus granulosus lysine specific histone demethylase 1A 0.0142 0.0108 0.0108
Echinococcus multilocularis Blood coagulation inhibitor, Disintegrin 0.0038 0.001 0.0012
Onchocerca volvulus 0.01 0.0069 0.0998
Plasmodium falciparum protoporphyrinogen oxidase 0.0142 0.0108 0.2613
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0142 0.0108 0.2613
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0079 0.0049 0.1054
Brugia malayi hypothetical protein 0.0245 0.0205 0.0205
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0039 0.0011 0.0011
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.258 0.241 0.241
Trypanosoma cruzi protein arginine n-methyltransferase 7 0.0088 0.0057 0.0785
Brugia malayi Will die slowly protein 0.0148 0.0114 0.0114
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.6492 0.6102 0.7623
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0111 0.0079 0.1154
Echinococcus multilocularis calcium dependent protein kinase 0.003 0.0003 0.0003
Mycobacterium tuberculosis Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) 0.0467 0.0415 1
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 1.0621 1 1
Schistosoma mansoni hypothetical protein 0.0055 0.0026 0.0026
Echinococcus granulosus subfamily M12B unassigned peptidase 0.0091 0.006 0.006
Schistosoma mansoni integrin beta subunit 0.2242 0.2091 0.2091
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0142 0.0108 0.2189
Loa Loa (eye worm) hypothetical protein 0.0045 0.0016 0.0016
Loa Loa (eye worm) acyl carrier protein 0.0038 0.001 0.001
Giardia lamblia Neurogenic locus notch-like protein 0.01 0.0069 0.0107
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0467 0.0415 0.0518
Loa Loa (eye worm) glutamate receptor 1 0.0031 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.01 0.0069 0.0069
Mycobacterium tuberculosis Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) 0.0467 0.0415 1
Toxoplasma gondii type I fatty acid synthase, putative 0.0084 0.0053 0.1286
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0039 0.0011 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.2113 0.1969 0.3226
Loa Loa (eye worm) TK/ROR protein kinase 0.0032 0.0004 0.0004
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.075 0.0682 1
Brugia malayi Reprolysin 0.0053 0.0024 0.0024
Mycobacterium leprae PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5) 0.0467 0.0415 1
Echinococcus granulosus protein arginine N methyltransferase 7 0.0088 0.0057 0.0057
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0699 0.0634 0.0793
Onchocerca volvulus 0.003 0.0003 0.0044
Loa Loa (eye worm) hypothetical protein 0.0034 0.0006 0.0006
Schistosoma mansoni adam (A disintegrin and metalloprotease 0.0119 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0059 0.003 0.003
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.008 0.005 1
Schistosoma mansoni growth factor receptor-bound protein 0.0132 0.0099 0.0099
Schistosoma mansoni hypothetical protein 0.0105 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0036 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0036 0.0008 0.0008
Brugia malayi hypothetical protein 0.0039 0.0011 0.0011
Trichomonas vaginalis teneurin and N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, putative 0.01 0.0069 0.0113
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0004 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0023 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.2113 0.1969 0.3226
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0023 0.0037
Echinococcus multilocularis adam 0.0219 0.0181 0.0226
Loa Loa (eye worm) hypothetical protein 1.0621 1 1
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0053 0.0024 0.0584
Plasmodium falciparum subtilisin-like protease 3 0.0467 0.0415 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0003 0.0003
Schistosoma mansoni chromatin regulatory protein sir2 0.075 0.0682 0.0682
Onchocerca volvulus 0.0097 0.0065 0.0947
Leishmania major UDP-galactopyranose mutase 0.0142 0.0108 0.1542
Trichomonas vaginalis alpha-L-fucosidase, putative 0.0051 0.0023 0.0037
Loa Loa (eye worm) hypothetical protein 0.0039 0.0011 0.0011
Schistosoma mansoni site-1 peptidase (S08 family) 0.0467 0.0415 0.0415
Toxoplasma gondii kringle domain-containing protein 0.0032 0.0004 0.0103
Loa Loa (eye worm) hypothetical protein 0.0717 0.0652 0.0652
Loa Loa (eye worm) hypothetical protein 0.0028 0.0001 0.0001
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0068 0.0038 0.0406
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0105 0.0074 0.0092
Plasmodium falciparum plasmepsin I 0.0039 0.0011 0.026
Echinococcus multilocularis tissue type plasminogen activator 0.0032 0.0004 0.0005
Brugia malayi hypothetical protein 0.0036 0.0008 0.0008
Brugia malayi hypothetical protein 0.0097 0.0065 0.0065
Brugia malayi Guanylate kinase family protein 0.0031 0.0003 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0023 0.0037
Plasmodium vivax aspartyl protease, putative 0.0039 0.0011 0.026
Brugia malayi hypothetical protein 0.0036 0.0008 0.0008
Schistosoma mansoni septate junction protein 0.0061 0.0031 0.0031
Brugia malayi CUB domain containing protein 0.003 0.0003 0.0003
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0686 0.0621 0.0621
Schistosoma mansoni inhibitor of apoptosis protein 0.0105 0.0074 0.0074
Plasmodium falciparum calcium-dependent protein kinase 4 0.0031 0.0004 0.0092
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0105 0.0074 0.0074
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0047 0.0019 0.0019
Echinococcus multilocularis discoidin domain receptor 0.0051 0.0023 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0467 0.0415 0.068
Brugia malayi SWIRM domain containing protein 0.0059 0.003 0.003
Entamoeba histolytica PH domain containing protein kinase, putative 0.008 0.0049 0.0725
Brugia malayi hypothetical protein 0.0036 0.0008 0.0008
Echinococcus multilocularis neuroendocrine convertase 2 0.6709 0.6307 0.7879
Entamoeba histolytica protein kinase, putative 0.0031 0.0004 0.0056
Plasmodium vivax plasmepsin IV, putative 0.0039 0.0011 0.026
Leishmania major subtilisin-like serine peptidase 0.0467 0.0415 0.6061
Echinococcus granulosus glutamate NMDA receptor subunit 0.0265 0.0224 0.0224
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0031 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0585 0.0526 0.0526
Echinococcus multilocularis 0.8508 0.8005 1
Giardia lamblia Sirtuin type 2 0.0111 0.0079 0.0134
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0088 0.0057 0.0094
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.0111 0.0079 0.0134
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0023 0.0037
Loa Loa (eye worm) hypothetical protein 0.004 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.01 0.0069 0.0069
Brugia malayi Stress-activated protein kinase jnk-1 0.0236 0.0197 0.0197
Giardia lamblia High cysteine protein 0.01 0.0069 0.0107
Echinococcus multilocularis discoidin domain containing receptor 2 0.0051 0.0023 0.0029
Brugia malayi EGF-like domain containing protein 0.01 0.0069 0.0069
Schistosoma mansoni serine/threonine protein kinase 0.0236 0.0197 0.0197
Loa Loa (eye worm) hypothetical protein 0.0091 0.006 0.006
Schistosoma mansoni chromatin regulatory protein sir2 0.0111 0.0079 0.0079
Toxoplasma gondii subtilisin SUB10 0.0467 0.0415 1
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0157 0.0122 0.02
Trichomonas vaginalis conserved hypothetical protein 0.0467 0.0415 0.068
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0467 0.0415 0.068
Mycobacterium ulcerans polyketide synthase 0.0079 0.0049 0.0665
Echinococcus multilocularis histone arginine methyltransferase CARMER 0.0088 0.0057 0.0072
Schistosoma mansoni glutamate receptor NMDA 0.0265 0.0224 0.0224
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0031 0.0004 0.0004
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0111 0.0079 0.0098
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0497 0.0444 0.6483
Brugia malayi Lectin C-type domain containing protein 0.003 0.0003 0.0003
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0031 0.0004 0.0092
Echinococcus multilocularis nuclear receptor 2C2 associated protein 0.0051 0.0023 0.0029
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0047 0.0019 0.0024
Echinococcus multilocularis glutamate receptor 2 0.0047 0.0019 0.0024
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0031 0.0004 0.0004
Echinococcus multilocularis epidermal growth factor receptor 0.0657 0.0594 0.0742
Trichomonas vaginalis WD repeat domain, putative 0.0148 0.0114 0.0187
Brugia malayi Glutamate receptor 1 precursor 0.0031 0.0004 0.0004
Echinococcus multilocularis discoidin domain containing receptor 2 0.0051 0.0023 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.2113 0.1969 0.3226
Toxoplasma gondii histone deacetylase SIR2 0.0111 0.0079 0.1896
Echinococcus granulosus histone arginine methyltransferase CARMER 0.0088 0.0057 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0023 0.0037
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0084 0.0053 0.0787
Schistosoma mansoni hypothetical protein 0.0032 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0055 0.0026 0.0026
Toxoplasma gondii histone arginine methyltransferase PRMT4/CARM1 0.0088 0.0057 0.1386
Schistosoma mansoni memapsin-2 (A01 family) 0.0039 0.0011 0.0011
Schistosoma mansoni cathepsin D (A01 family) 0.0039 0.0011 0.0011
Onchocerca volvulus 0.0051 0.0023 0.0331
Echinococcus multilocularis MAM 0.0097 0.0065 0.0082
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0467 0.0415 0.068
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0467 0.0415 0.068
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0084 0.0053 0.1171
Brugia malayi GCC2 and GCC3 family protein 0.0045 0.0016 0.0016
Mycobacterium leprae Probable polyketide synthase Pks1 0.0084 0.0053 0.0787
Schistosoma mansoni chromatin regulatory protein sir2 0.0111 0.0079 0.0079
Echinococcus multilocularis subfamily M12B unassigned peptidase 0.0091 0.006 0.0075
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0031 0.0004 0.0092
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0488 0.0435 0.0435
Brugia malayi Suppressor of lurcher protein 1 precursor 0.003 0.0003 0.0003
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0467 0.0415 0.068
Schistosoma mansoni discoidin domain receptor 0.0051 0.0023 0.0023
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0031 0.0004 0.0004
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0467 0.0415 0.0415
Mycobacterium ulcerans membrane-anchored serine protease (mycosin), MycP4 0.0467 0.0415 1
Loa Loa (eye worm) TK/ALK protein kinase 0.0097 0.0065 0.0065
Brugia malayi Calcium binding EGF domain containing protein 0.004 0.0012 0.0012
Toxoplasma gondii histone arginine methyltransferase PRMT3 0.0088 0.0057 0.1386
Brugia malayi hypothetical protein 0.0585 0.0526 0.0526
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0039 0.0011 0.0011
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0467 0.0415 0.068
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0467 0.0415 0.068
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0063 0.0034 0.0281
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0004 0.0004
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0221 0.0183 0.0183
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0467 0.0415 0.068
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0111 0.0079 0.1098
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0031 0.0004 0.0092
Loa Loa (eye worm) hypothetical protein 0.0759 0.069 0.069
Loa Loa (eye worm) hypothetical protein 0.0311 0.0268 0.0268
Echinococcus granulosus glutamate receptor 2 0.0047 0.0019 0.0019
Giardia lamblia Furin precursor putative serine protease 0.2113 0.1969 0.5331
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0221 0.0183 0.0183
Giardia lamblia Transcriptional regulator, Sir2 family 0.0111 0.0079 0.0134
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0112 0.008 0.01
Mycobacterium ulcerans thioesterase 0.0068 0.0038 0.0406
Schistosoma mansoni protein arginine n-methyltransferase 0.0088 0.0057 0.0057
Onchocerca volvulus 0.0036 0.0008 0.0113
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0039 0.0011 0.0011
Echinococcus granulosus discoidin domain containing receptor 2 0.0051 0.0023 0.0023
Schistosoma mansoni hypothetical protein 0.003 0.0003 0.0003
Brugia malayi hypothetical protein 0.0039 0.0011 0.0011
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0142 0.0108 0.2613
Schistosoma mansoni SWI/SNF complex-related 0.0059 0.003 0.003
Mycobacterium tuberculosis Possible oxidoreductase 0.0142 0.0108 0.2515
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0467 0.0415 0.068
Toxoplasma gondii rhoptry neck protein RON1 0.0036 0.0008 0.0188
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0111 0.0079 0.0129
Brugia malayi hypothetical protein 0.0142 0.0108 0.0108
Echinococcus multilocularis fibrillin 2 0.01 0.0069 0.0086
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0157 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0142 0.0108 0.0108
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0046 0.0018 0.0309
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0055 0.0026 0.0026
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.008 0.005 1
Brugia malayi protein kinase C II. 0.0097 0.0066 0.0066
Plasmodium vivax aspartyl protease, putative 0.0039 0.0011 0.026
Toxoplasma gondii type I fatty acid synthase, putative 0.0058 0.0029 0.0701
Plasmodium falciparum calcium-dependent protein kinase 3 0.0031 0.0004 0.0092
Brugia malayi Sex muscle abnormal protein 5 0.0132 0.0099 0.0099
Mycobacterium leprae PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3) 0.0467 0.0415 1
Trypanosoma brucei Protein arginine N-methyltransferase 1 catalytic subunit 0.0245 0.0205 0.297
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0023 0.0037
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0245 0.0205 0.2965
Schistosoma mansoni chromatin regulatory protein sir2 0.075 0.0682 0.0682
Loa Loa (eye worm) CUB domain-containing protein 0.003 0.0003 0.0003
Plasmodium falciparum plasmepsin V 0.0436 0.0385 0.9286
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0055 0.0026 0.0026
Echinococcus multilocularis nmda type glutamate receptor 0.0112 0.008 0.01
Brugia malayi amine oxidase, flavin-containing family protein 0.0201 0.0164 0.0164
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0105 0.0074 0.0074
Echinococcus multilocularis cubilin 0.003 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0642 0.058 0.058
Trypanosoma cruzi arginine N-methyltransferase, type I 0.0088 0.0057 0.0785
Onchocerca volvulus 0.0097 0.0065 0.0947
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0023 0.0037
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0088 0.0057 0.0094
Toxoplasma gondii aspartyl protease 0.0039 0.0011 0.026
Brugia malayi EGF-like domain containing protein 0.01 0.0069 0.0069
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0039 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0036 0.0008 0.0008
Mycobacterium leprae PROBABLE CONSERVED TRANSMEMBRANE PROTEIN 0.0051 0.0023 0.0008
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0467 0.0415 0.068
Plasmodium vivax LCCL domain-containing protein 0.0051 0.0023 0.055
Echinococcus granulosus lysine specific histone demethylase 1A 0.0699 0.0634 0.0634
Echinococcus multilocularis integrin alpha ps 0.052 0.0465 0.0581
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0119 0.0087 0.1985
Plasmodium falciparum plasmepsin IX 0.0039 0.0011 0.026
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0467 0.0415 0.068
Toxoplasma gondii bicoid-interacting protein BIN3 0.0088 0.0057 0.1386
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0142 0.0108 0.2613
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0023 0.0037
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0497 0.0444 0.6483
Loa Loa (eye worm) hypothetical protein 0.0117 0.0085 0.0085
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.2684 0.2508 0.2508
Loa Loa (eye worm) DEAH box polypeptide 35 0.0034 0.0006 0.0006
Brugia malayi Integrin beta pat-3 precursor 0.3824 0.3584 0.3584
Echinococcus granulosus Blood coagulation inhibitor Disintegrin 0.0038 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0097 0.0065 0.0065
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0105 0.0074 0.0074
Brugia malayi EGF-like domain containing protein 0.01 0.0069 0.0069
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0467 0.0415 0.068
Schistosoma mansoni serine/threonine protein kinase 0.0031 0.0004 0.0004
Toxoplasma gondii PA14 domain-containing protein 0.0051 0.0023 0.055
Toxoplasma gondii subtilisin SUB4 0.0467 0.0415 1
Loa Loa (eye worm) reprolysin 0.0091 0.006 0.006
Toxoplasma gondii subtilisin SUB6 0.0467 0.0415 1
Schistosoma mansoni furin-1 (S08 family) 0.4596 0.4313 0.4313
Trypanosoma brucei protein arginine n-methyltransferase 7 0.0088 0.0057 0.0791
Trypanosoma cruzi UDP-galactopyranose mutase 0.0142 0.0108 0.1536
Echinococcus granulosus protein kinase c epsilon type 0.0097 0.0066 0.0066
Echinococcus granulosus integrin alpha ps 0.0582 0.0523 0.0523
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0023 0.0037
Schistosoma mansoni hypothetical protein 0.0097 0.0065 0.0065
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.075 0.0682 1
Trichomonas vaginalis alpha-L-fucosidase, putative 0.0051 0.0023 0.0037
Plasmodium falciparum transcriptional regulatory protein sir2a 0.0111 0.0079 0.1896
Loa Loa (eye worm) hypothetical protein 0.0032 0.0004 0.0004
Plasmodium falciparum LCCL domain-containing protein 0.0051 0.0023 0.055
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.6492 0.6102 1
Giardia lamblia Hypothetical protein 0.075 0.0682 0.1793
Toxoplasma gondii subtilisin SUB12 0.0467 0.0415 1
Plasmodium vivax aspartyl proteinase, putative 0.0039 0.0011 0.026
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0152 0.0118 0.0118
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0047 0.0019 0.0019
Schistosoma mansoni site-1 peptidase (S08 family) 0.0467 0.0415 0.0415
Echinococcus multilocularis protein arginine N methyltransferase 7 0.0088 0.0057 0.0072
Trypanosoma brucei SIR2-like protein 4, putative 0.0111 0.0079 0.1104
Plasmodium falciparum cysteine repeat modular protein 1 0.0032 0.0004 0.0103
Loa Loa (eye worm) transcriptional regulator 0.0111 0.0079 0.0079
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0064 0.0035 0.0712
Echinococcus granulosus chromatin regulatory protein sir2 0.075 0.0682 0.0682
Schistosoma mansoni hypothetical protein 0.2113 0.1969 0.1969
Mycobacterium tuberculosis Transcriptional regulatory protein 0.0111 0.0079 0.1789
Brugia malayi proprotein convertase 2 0.6709 0.6307 0.6307
Echinococcus granulosus integrin beta 2 0.2827 0.2642 0.2642
Echinococcus granulosus inhibitor of apoptosis protein 0.0105 0.0074 0.0074
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0084 0.0053 0.0787
Brugia malayi NAD-dependent deacetylase SIRT1 0.0111 0.0079 0.0079
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0076 0.0046 0.0997
Entamoeba histolytica hypothetical protein 0.0245 0.0205 0.3009
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.6492 0.6102 1
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0047 0.0019 0.0024
Echinococcus granulosus fibrillin 1 0.0103 0.0071 0.0071
Onchocerca volvulus 0.003 0.0003 0.0044
Loa Loa (eye worm) bone morphogenetic protein 1b 0.003 0.0003 0.0003
Schistosoma mansoni amine oxidase 0.0142 0.0108 0.0108
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0091 0.006 0.006
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0157 0.0122 0.02
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0004 0.0005
Echinococcus granulosus growth factor receptor bound protein 2 0.0132 0.0099 0.0099
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0047 0.0019 0.0024
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0075 0.0045 0.0045
Brugia malayi EGF-like domain containing protein 0.01 0.0069 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.2113 0.1969 0.3226
Brugia malayi hypothetical protein 0.0036 0.0008 0.0008
Echinococcus multilocularis 0.0142 0.0108 0.0135
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.008 0.005 0.1092
Schistosoma mansoni integrin alpha-ps 0.0333 0.0288 0.0288
Schistosoma mansoni hypothetical protein 0.0055 0.0026 0.0026

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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