Detailed information for compound 882238

Basic information

Technical information
  • TDR Targets ID: 882238
  • Name: N-(2-bromophenyl)-4-(4-ethyl-2-oxo-1,3-oxazol idin-3-yl)piperidine-1-carboxamide
  • MW: 396.279 | Formula: C17H22BrN3O3
  • H donors: 1 H acceptors: 2 LogP: 2.99 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCC1COC(=O)N1C1CCN(CC1)C(=O)Nc1ccccc1Br
  • InChi: 1S/C17H22BrN3O3/c1-2-12-11-24-17(23)21(12)13-7-9-20(10-8-13)16(22)19-15-6-4-3-5-14(15)18/h3-6,12-13H,2,7-11H2,1H3,(H,19,22)
  • InChiKey: XBKLHVCUBGYJRL-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-(2-bromophenyl)-4-(4-ethyl-2-oxo-oxazolidin-3-yl)piperidine-1-carboxamide
  • N-(2-bromophenyl)-4-(4-ethyl-2-oxo-3-oxazolidinyl)-1-piperidinecarboxamide
  • N-(2-bromophenyl)-4-(4-ethyl-2-keto-oxazolidin-3-yl)piperidine-1-carboxamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) SRC-1 0.0049 0.014 0.0254
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.0025 0.0041 0.0072
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.0028 0.0048
Plasmodium falciparum ataxin-2 like protein, putative 0.0176 0.0667 0.1212
Trypanosoma brucei PAB1-binding protein , putative 0.0176 0.0667 0.1221
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0058 0.018 0.0326
Echinococcus granulosus epidermal growth factor receptor 0.0167 0.0628 0.1148
Trypanosoma cruzi target of rapamycin kinase 3 0.0036 0.0089 0.016
Echinococcus multilocularis GPCR, family 2 0.0048 0.0139 0.0137
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.001
Leishmania major cathepsin L-like protease 0.0017 0.0009 0.0013
Loa Loa (eye worm) hypothetical protein 0.003 0.0063 0.0112
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0145 0.0535 0.0979
Brugia malayi hypothetical protein 0.0024 0.0039 0.0067
Trypanosoma cruzi cruzipain precursor, putative 0.0065 0.0207 0.0376
Schistosoma mansoni tubulin subunit beta 0.1336 0.545 1
Brugia malayi Fibronectin type III domain containing protein 0.0024 0.0039 0.0067
Loa Loa (eye worm) acetyltransferase 0.0148 0.0551 0.1007
Brugia malayi secreted modular calcium-binding protein 1 0.0039 0.0099 0.0177
Plasmodium falciparum cysteine proteinase falcipain 3 0.0017 0.0009 0.0003
Schistosoma mansoni hypothetical protein 0.0206 0.0788 0.1446
Echinococcus granulosus tyrosine protein kinase HCK 0.0035 0.0084 0.0151
Trichomonas vaginalis glutaminase, putative 0.0287 0.1122 0.2056
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0038 0.0067
Loa Loa (eye worm) hypothetical protein 0.0593 0.2384 0.4373
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0094 0.0169
Loa Loa (eye worm) patched family protein 0.003 0.0063 0.0112
Toxoplasma gondii alpha tubulin TUBA1 0.0999 0.406 0.7449
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0214 0.082 0.1501
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0009 0.0013
Onchocerca volvulus Protein patched homolog 0.003 0.0063 0.0291
Echinococcus multilocularis tubulin alpha chain 0.0999 0.406 0.4058
Leishmania major beta tubulin 0.1336 0.545 1
Trichomonas vaginalis D-aminoacylase, putative 0.0145 0.0535 0.0979
Loa Loa (eye worm) hypothetical protein 0.003 0.0063 0.0112
Loa Loa (eye worm) TK protein kinase 0.0042 0.0113 0.0203
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0053 0.0157 0.0285
Leishmania major beta tubulin 0.1336 0.545 1
Onchocerca volvulus 0.0049 0.0141 0.0711
Plasmodium falciparum alpha tubulin 2 0.0999 0.406 0.7446
Leishmania major beta tubulin 0.1336 0.545 1
Echinococcus multilocularis Tubulin alpha 1 chain 0.0999 0.406 0.4058
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0654 0.1197
Schistosoma mansoni tyrosine kinase 0.0019 0.0018 0.0033
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0145 0.0535 0.0982
Brugia malayi hypothetical protein 0.003 0.0063 0.0112
Brugia malayi nuclear hormone receptor family member odr-7 0.0047 0.0134 0.0242
Toxoplasma gondii target of rapamycin (TOR), putative 0.0034 0.0079 0.0145
Leishmania major alpha tubulin 0.0999 0.406 0.7449
Loa Loa (eye worm) latrophilin receptor protein 2 0.0048 0.0139 0.0251
Plasmodium falciparum tubulin beta chain 0.1336 0.545 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0063 0.0112
Echinococcus granulosus TGF beta signal transducer SmadC 0.0024 0.004 0.0069
Trypanosoma cruzi tubulin gamma chain 0.0804 0.3255 0.5971
Echinococcus multilocularis Tubulin beta 2C chain 0.1336 0.545 0.5449
Brugia malayi hypothetical protein 0.0047 0.0134 0.0242
Giardia lamblia Gamma tubulin 0.0804 0.3255 0.5967
Loa Loa (eye worm) hypothetical protein 0.0047 0.0134 0.0242
Loa Loa (eye worm) hypothetical protein 0.0047 0.0134 0.0242
Trypanosoma brucei beta tubulin 0.1336 0.545 1
Plasmodium falciparum eukaryotic initiation factor 4A 0.0025 0.0041 0.0062
Brugia malayi nuclear receptor RXR 0.0053 0.0157 0.0285
Brugia malayi Patched family protein 0.003 0.0063 0.0112
Mycobacterium ulcerans lipase LipD 0.0145 0.0535 0.3917
Trichomonas vaginalis glucosylceramidase, putative 0.0264 0.1029 0.1886
Brugia malayi Cell division protein ftsZ 0.0343 0.1355 0.2483
Entamoeba histolytica hypothetical protein 0.0073 0.0242 0.0444
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0025 0.0041 0.0076
Echinococcus granulosus dnaJ subfamily B 0.0416 0.1656 0.3037
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0044 0.0119 0.0218
Echinococcus granulosus tubulin subunit beta 0.1336 0.545 1
Echinococcus multilocularis integrin alpha ps 0.007 0.0227 0.0225
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0046 0.0127 0.023
Onchocerca volvulus Protein patched homolog 0.003 0.0063 0.0291
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0009 0.0007
Echinococcus granulosus epidermal growth factor receptor 0.0307 0.1207 0.2212
Toxoplasma gondii hypothetical protein 0.003 0.0063 0.0116
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0017 0.0009 0.0003
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0025 0.0041 0.0072
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0046 0.0127 0.023
Loa Loa (eye worm) RecQ helicase 0.0042 0.0112 0.0201
Loa Loa (eye worm) Smad1 0.0024 0.004 0.0069
Loa Loa (eye worm) hypothetical protein 0.003 0.0063 0.0112
Loa Loa (eye worm) glutathione reductase 0.0048 0.0137 0.0248
Brugia malayi beta-lactamase family protein 0.0145 0.0535 0.0979
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0057 0.0173 0.0171
Leishmania major alpha tubulin 0.0999 0.406 0.7449
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0049 0.014 0.0138
Brugia malayi Furin-like cysteine rich region family protein 0.0307 0.1207 0.2212
Schistosoma mansoni hypothetical protein 0.0128 0.0467 0.0858
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0021 0.0027 0.0049
Brugia malayi Nuclear hormone receptor family member nhr-14 0.01 0.0353 0.0644
Loa Loa (eye worm) hypothetical protein 0.003 0.0063 0.0112
Echinococcus granulosus Solute carrier organic anion transporter family 0.0057 0.0173 0.0314
Onchocerca volvulus 0.0047 0.0134 0.0672
Schistosoma mansoni tubulin subunit gamma 0.0804 0.3255 0.5972
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0118 0.0424 0.0775
Plasmodium vivax RNA helicase-1, putative 0.0025 0.0041 0.0062
Loa Loa (eye worm) hypothetical protein 0.017 0.0639 0.1169
Brugia malayi Patched related family protein 12 0.003 0.0063 0.0112
Loa Loa (eye worm) hypothetical protein 0.003 0.0063 0.0112
Brugia malayi Patched family protein 0.003 0.0063 0.0112
Brugia malayi Nuclear hormone receptor family member nhr-40 0.01 0.0353 0.0644
Echinococcus granulosus tubulin alpha 1C chain 0.0999 0.406 0.7449
Echinococcus multilocularis tubulin alpha 3 chain 0.0999 0.406 0.4058
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0216 0.0393
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.01 0.0353 0.0351
Echinococcus granulosus tubulin subunit TubB 0.0999 0.406 0.7449
Echinococcus granulosus neuropeptide receptor A26 0.0479 0.1917 0.3515
Schistosoma mansoni hypothetical protein 0.0049 0.0141 0.0259
Trichomonas vaginalis glucosylceramidase, putative 0.0264 0.1029 0.1886
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0039 0.0099 0.0177
Loa Loa (eye worm) integrin beta-2 0.0319 0.1254 0.2298
Toxoplasma gondii LsmAD domain-containing protein 0.0176 0.0667 0.1224
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0079 0.0141
Trichomonas vaginalis tubulin alpha chain, putative 0.0749 0.303 0.5558
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0021 0.0027 0.0049
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0128 0.0467 0.0465
Loa Loa (eye worm) hypothetical protein 0.003 0.0063 0.0112
Loa Loa (eye worm) nuclear receptor NHR-67 0.0047 0.0134 0.0242
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.032 0.0588
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0111 0.0395 0.0393
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.01 0.0353 0.0647
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0058 0.018 0.046
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0025 0.0041 0.0039
Loa Loa (eye worm) hypothetical protein 0.003 0.0063 0.0112
Echinococcus granulosus tyrosine kinase 0.0042 0.0113 0.0203
Brugia malayi nuclear receptor RXR 0.0047 0.0134 0.0242
Trypanosoma cruzi major cysteine proteinase, putative 0.0051 0.0149 0.027
Brugia malayi MH1 domain containing protein 0.0024 0.004 0.0069
Leishmania major cathepsin L-like protease 0.0017 0.0009 0.0013
Brugia malayi Patched related family protein 10 0.003 0.0063 0.0112
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0123 0.0445 0.0817
Echinococcus granulosus mothers against decapentaplegic 5 0.0024 0.004 0.0069
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0145 0.0535 0.141
Loa Loa (eye worm) hypothetical protein 0.0039 0.0099 0.0177
Entamoeba histolytica tubulin gamma chain 0.0804 0.3255 0.5972
Echinococcus multilocularis agrin 0.0039 0.0099 0.0097
Loa Loa (eye worm) hypothetical protein 0.0048 0.0139 0.0251
Echinococcus granulosus tyrosine protein kinase Src42A 0.0049 0.014 0.0254
Onchocerca volvulus 0.0057 0.0173 0.0881
Leishmania major beta tubulin 0.1336 0.545 1
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.007 0.0124
Brugia malayi SRC-1 0.0049 0.014 0.0254
Schistosoma mansoni single-minded 0.005 0.0143 0.0262
Echinococcus multilocularis tubulin beta 1 chain 0.1336 0.545 0.5449
Brugia malayi Tyrosine-protein kinase abl-1 0.013 0.0474 0.0866
Brugia malayi Kelch motif family protein 0.0048 0.0139 0.0251
Schistosoma mansoni hypothetical protein 0.0206 0.0788 0.1446
Loa Loa (eye worm) nuclear hormone receptor 0.0047 0.0134 0.0242
Brugia malayi Cathepsin L-like precursor 0.0017 0.0009 0.0013
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0053 0.0157 0.0289
Plasmodium vivax delta tubulin, putative 0.0343 0.1355 0.2475
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.01 0.0353 0.0351
Onchocerca volvulus 0.0406 0.1614 0.8628
Toxoplasma gondii ABC1 family protein 0.0145 0.0535 0.0982
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0047 0.0134 0.0132
Brugia malayi beta-tubulin, identical 0.1336 0.545 1
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0201 0.0767 0.1404
Brugia malayi ecdysteroid receptor 0.01 0.0353 0.0644
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0009 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0079 0.0141
Brugia malayi orphan nuclear receptor NR2E1 0.0047 0.0134 0.0242
Schistosoma mansoni tyrosine kinase 0.0161 0.0605 0.1109
Loa Loa (eye worm) hypothetical protein 0.01 0.0353 0.0644
Trichomonas vaginalis tubulin beta chain, putative 0.0999 0.406 0.7449
Loa Loa (eye worm) TK protein kinase 0.0109 0.0388 0.0709
Echinococcus multilocularis Tubulin beta 2C chain 0.1336 0.545 0.5449
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0153 0.057 0.1043
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.01 0.0353 0.0351
Trypanosoma brucei zeta tubulin, putative 0.0905 0.3674 0.6741
Echinococcus granulosus tubulin alpha 3 chain 0.0999 0.406 0.7449
Loa Loa (eye worm) hypothetical protein 0.003 0.0063 0.0112
Leishmania major cysteine peptidase A (CPA) 0.0017 0.0009 0.0013
Loa Loa (eye worm) hypothetical protein 0.0153 0.057 0.1043
Leishmania major hypothetical protein, conserved 0.0176 0.0667 0.1221
Schistosoma mansoni tyrosine kinase 0.0161 0.0605 0.1109
Echinococcus granulosus tubulin alpha chain 0.0999 0.406 0.7449
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0038 0.0082
Schistosoma mansoni coup transcription factor 0.01 0.0353 0.0647
Echinococcus granulosus smad 0.0024 0.004 0.0069
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0019 0.0018 0.0033
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0009 0.0013
Loa Loa (eye worm) hypothetical protein 0.0038 0.0094 0.0169
Loa Loa (eye worm) alpha-tubulin 0.0999 0.406 0.7449
Schistosoma mansoni hypothetical protein 0.0073 0.0242 0.0444
Schistosoma mansoni tyrosine kinase 0.0167 0.0628 0.1152
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0041 0.0071
Echinococcus multilocularis Tubulin beta 2C chain 0.1336 0.545 0.5449
Mycobacterium tuberculosis Conserved protein 0.0145 0.0535 0.141
Echinococcus multilocularis tubulin subunit TubB 0.0999 0.406 0.4058
Onchocerca volvulus Glucosylceramidase homolog 0.0173 0.0654 0.3469
Schistosoma mansoni alpha tubulin 0.0999 0.406 0.7449
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0024 0.004 0.0073
Loa Loa (eye worm) hypothetical protein 0.01 0.0353 0.0644
Schistosoma mansoni integrin beta subunit 0.0188 0.0713 0.1309
Echinococcus granulosus geminin 0.1187 0.4834 0.8871
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.01 0.0353 0.0644
Trypanosoma brucei hypothetical protein, conserved 0.0048 0.0136 0.0245
Brugia malayi Bloom's syndrome protein homolog 0.0042 0.0112 0.0201
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0343 0.1355 1
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0111 0.0395 0.0712
Loa Loa (eye worm) hypothetical protein 0.003 0.0063 0.0112
Loa Loa (eye worm) hypothetical protein 0.0262 0.1018 0.1865
Loa Loa (eye worm) tubulin alpha 2 0.025 0.0968 0.1774
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0009 0.0013
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0025 0.0041 0.0062
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.017 0.0639 0.1172
Echinococcus multilocularis Niemann Pick C1 protein 0.0498 0.1992 0.199
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0048 0.0136 0.0249
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0025 0.0041 0.0072
Echinococcus granulosus Immunoglobulin 0.0021 0.0027 0.0045
Loa Loa (eye worm) hypothetical protein 0.0145 0.0535 0.0979
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0052 0.0092
Trypanosoma cruzi hypothetical protein, conserved 0.0145 0.0535 0.0979
Mycobacterium leprae Probable lipase LipE 0.0145 0.0535 0.3775
Trypanosoma brucei hypothetical protein, conserved 0.0145 0.0535 0.0979
Brugia malayi alpha-tubulin 0.0999 0.406 0.7449
Trypanosoma cruzi alpha tubulin, putative 0.0999 0.406 0.7449
Echinococcus multilocularis tubulin alpha 0.0749 0.303 0.3028
Onchocerca volvulus 0.005 0.0146 0.0738
Loa Loa (eye worm) hypothetical protein 0.0039 0.0099 0.0177
Brugia malayi Latrophilin receptor protein 2 0.0048 0.0139 0.0251
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0009 0.0013
Entamoeba histolytica tubulin alpha chain, putative 0.0999 0.406 0.7449
Schistosoma mansoni cpg binding protein 0.0061 0.0191 0.0351
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0038 0.007
Echinococcus multilocularis FTZ F1 alpha 0.01 0.0353 0.0351
Leishmania major zeta tubulin, putative 0.0905 0.3674 0.6741
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0042 0.0113 0.0111
Brugia malayi photoreceptor-specific nuclear receptor 0.01 0.0353 0.0644
Schistosoma mansoni survival motor neuron protein 0.0049 0.0141 0.0259
Loa Loa (eye worm) hypothetical protein 0.0468 0.1869 0.3428
Trichomonas vaginalis tubulin alpha chain, putative 0.1336 0.545 1
Brugia malayi MH2 domain containing protein 0.0359 0.142 0.2603
Plasmodium vivax glutathione reductase, putative 0.0048 0.0137 0.0238
Loa Loa (eye worm) hypothetical protein 0.0214 0.082 0.1501
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0343 0.1355 0.2483
Giardia lamblia GTOR 0.0046 0.0127 0.022
Echinococcus granulosus cpg binding protein 0.0061 0.0191 0.0347
Echinococcus granulosus tubulin epsilon chain 0.0803 0.3251 0.5965
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0038 0.0082
Mycobacterium ulcerans beta-lactamase 0.0145 0.0535 0.3917
Trypanosoma brucei beta tubulin 0.1336 0.545 1
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0111 0.0395 0.0722
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0053 0.0157 0.0155
Loa Loa (eye worm) hypothetical protein 0.0047 0.0134 0.0242
Echinococcus multilocularis tyrosine protein kinase Blk 0.0042 0.0113 0.0111
Echinococcus multilocularis Immunoglobulin 0.0021 0.0027 0.0025
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0008 0.001
Brugia malayi hypothetical protein 0.0176 0.0667 0.1221
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0009 0.0017
Brugia malayi hypothetical protein 0.003 0.0063 0.0112
Leishmania major beta tubulin 0.1336 0.545 1
Echinococcus multilocularis Smad4 0.0024 0.004 0.0038
Brugia malayi acetyltransferase, GNAT family protein 0.0148 0.0551 0.1007
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.007 0.0124
Brugia malayi sodium-independent organic anion transporter family protein 0.0057 0.0173 0.0314
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0094 0.0169
Schistosoma mansoni DNA helicase recq1 0.0029 0.0059 0.0108
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0009 0.0017
Plasmodium vivax tubulin beta chain, putative 0.1336 0.545 1
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0094 0.0092
Trypanosoma brucei alpha tubulin 0.0999 0.406 0.7449
Brugia malayi Patched family protein 0.003 0.0063 0.0112
Schistosoma mansoni tubulin subunit beta 0.1336 0.545 1
Schistosoma mansoni aryl hydrocarbon receptor 0.005 0.0143 0.0262
Brugia malayi nuclear receptor NHR-88 0.0047 0.0134 0.0242
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0048 0.0139 0.0251
Loa Loa (eye worm) hypothetical protein 0.0227 0.0877 0.1606
Loa Loa (eye worm) hypothetical protein 0.0145 0.0535 0.0979
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0505 0.2024 0.3713
Brugia malayi SPARC precursor 0.0039 0.0099 0.0177
Loa Loa (eye worm) hypothetical protein 0.0656 0.2644 0.4849
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0053 0.0157 0.0289
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0039 0.0099 0.0177
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0654 0.1197
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0067 0.0216 0.0393
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.01 0.0353 0.0644
Leishmania major beta tubulin 0.1336 0.545 1
Schistosoma mansoni integrin alpha-ps 0.0036 0.0089 0.0163
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.01 0.0353 0.0647
Echinococcus granulosus intermediate filament protein 0.0027 0.0052 0.0092
Echinococcus multilocularis expressed conserved protein 0.0467 0.1867 0.1866
Trypanosoma cruzi tubulin delta chain 0.0679 0.2742 0.503
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0039 0.0099 0.0181
Schistosoma mansoni lamin 0.0027 0.0052 0.0095
Trypanosoma cruzi epsilon tubulin, putative 0.0803 0.3251 0.5965
Loa Loa (eye worm) hypothetical protein 0.0086 0.0293 0.0534
Echinococcus multilocularis smad 0.0024 0.004 0.0038
Trichomonas vaginalis glucosylceramidase, putative 0.0264 0.1029 0.1886
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0039 0.0072
Mycobacterium tuberculosis Probable dehydrogenase 0.011 0.0392 0.1026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0089 0.0159
Loa Loa (eye worm) hypothetical protein 0.0024 0.0039 0.0069
Brugia malayi Integrin beta pat-3 precursor 0.0319 0.1254 0.2298
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0048 0.0139 0.0251
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.0242 0.024
Schistosoma mansoni retinoid-x-receptor (RXR) 0.01 0.0353 0.0647
Trichomonas vaginalis tubulin epsilon chain, putative 0.1336 0.545 1
Brugia malayi hypothetical protein 0.0166 0.0624 0.1142
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0042 0.0113 0.0203
Leishmania major alpha tubulin 0.0999 0.406 0.7449
Brugia malayi Patched family protein 0.003 0.0063 0.0112
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0207 0.0376
Loa Loa (eye worm) hypothetical protein 0.003 0.0063 0.0112
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.005 0.0089
Loa Loa (eye worm) hypothetical protein 0.0047 0.0134 0.0242
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0104 0.0177
Brugia malayi Patched family protein 0.003 0.0063 0.0112
Schistosoma mansoni alpha tubulin 0.0999 0.406 0.7449
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.001
Brugia malayi Patched family protein 0.003 0.0063 0.0112
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0111 0.0395 0.0722
Trypanosoma cruzi MFS transporter, putative 0.0057 0.0173 0.0314
Trypanosoma brucei alpha tubulin, putative 0.0406 0.1614 0.2959
Brugia malayi hypothetical protein 0.0227 0.0877 0.1606
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0009 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0041 0.0071
Echinococcus granulosus tubulin alpha 3 chain 0.0999 0.406 0.7449
Echinococcus multilocularis Niemann Pick C1 protein 0.0711 0.2873 0.2871
Brugia malayi Patched related family protein 4 0.003 0.0063 0.0112
Loa Loa (eye worm) isocitrate dehydrogenase 0.0111 0.0395 0.0722
Trichomonas vaginalis tubulin, putative 0.0406 0.1614 0.2959
Echinococcus multilocularis tubulin alpha chain 0.0999 0.406 0.4058
Leishmania major beta tubulin 0.1336 0.545 1
Echinococcus granulosus Smad4 0.0024 0.004 0.0069
Brugia malayi sodium-independent organic anion transporter family protein 0.0057 0.0173 0.0314
Echinococcus granulosus lamin dm0 0.0027 0.0052 0.0092
Schistosoma mansoni nuclear hormone receptor 0.0047 0.0134 0.0246
Toxoplasma gondii patched family protein 0.003 0.0063 0.0116
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0017 0.0009 0.0003
Brugia malayi beta-lactamase 0.0145 0.0535 0.0979
Echinococcus multilocularis mothers against decapentaplegic 5 0.0024 0.004 0.0038
Loa Loa (eye worm) hypothetical protein 0.0999 0.406 0.7449
Echinococcus granulosus tubulin gamma 1 chain 0.0804 0.3255 0.5971
Leishmania major cathepsin L-like protease 0.0065 0.0207 0.0376
Schistosoma mansoni Smad4 0.0024 0.004 0.0073
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0038 0.0228
Trypanosoma brucei zeta tubulin 0.0905 0.3674 0.6741
Loa Loa (eye worm) hypothetical protein 0.003 0.0063 0.0112
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0656 0.2644 0.4849
Plasmodium vivax tubulin epsilon chain, putative 0.0803 0.3251 0.5961
Loa Loa (eye worm) hypothetical protein 0.003 0.0063 0.0112
Loa Loa (eye worm) hypothetical protein 0.0053 0.0157 0.0285
Loa Loa (eye worm) tubulin alpha 2 0.0656 0.2644 0.4849
Echinococcus granulosus Tubulin beta 2C chain 0.1336 0.545 1
Plasmodium vivax ataxin-2 like protein, putative 0.0176 0.0667 0.1212
Brugia malayi Tubulin alpha-2 chain 0.0999 0.406 0.7449
Schistosoma mansoni hypothetical protein 0.0048 0.0139 0.0254
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0013 0.0011
Onchocerca volvulus 0.0039 0.0099 0.0481
Schistosoma mansoni organic anion transporter 0.0057 0.0173 0.0317
Echinococcus multilocularis follistatin 0.0039 0.0099 0.0097
Echinococcus granulosus FTZ F1 alpha 0.01 0.0353 0.0644
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.001
Brugia malayi isocitrate dehydrogenase 0.0111 0.0395 0.0722
Trichomonas vaginalis glucosylceramidase, putative 0.0264 0.1029 0.1886
Leishmania major beta tubulin 0.1336 0.545 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0127 0.023
Echinococcus granulosus tubulin beta 4A class IVa 0.1336 0.545 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0046 0.0127 0.023
Brugia malayi Tyrosine-protein kinase abl-1 0.0099 0.0349 0.0637
Plasmodium falciparum lipid/sterol:H+ symporter 0.003 0.0063 0.0102
Trypanosoma cruzi hypothetical protein, conserved 0.0145 0.0535 0.0979
Brugia malayi sodium-independent organic anion transporter family protein 0.0057 0.0173 0.0314
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0008 0.001
Onchocerca volvulus 0.01 0.0353 0.1847
Brugia malayi Protein kinase domain containing protein 0.0101 0.0355 0.0648
Loa Loa (eye worm) glutaminase 0.0287 0.1122 0.2056
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0039 0.0099 0.0181
Echinococcus multilocularis neuropeptide s receptor 0.0479 0.1917 0.1915
Leishmania major cathepsin L-like protease 0.0017 0.0009 0.0013
Loa Loa (eye worm) hypothetical protein 0.0057 0.0173 0.0314
Echinococcus granulosus GPCR family 2 0.0048 0.0139 0.0251
Mycobacterium ulcerans cell division protein FtsZ 0.0343 0.1355 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.01 0.0353 0.0647
Schistosoma mansoni hypothetical protein 0.0105 0.0373 0.0685
Mycobacterium tuberculosis Probable oxidoreductase 0.0122 0.0442 0.1162
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0148 0.0551 0.0549
Echinococcus granulosus tyrosine protein kinase Lyn 0.0049 0.014 0.0254
Echinococcus granulosus tubulin alpha chain 0.0999 0.406 0.7449
Trichomonas vaginalis conserved hypothetical protein 0.0343 0.1355 0.2483
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0145 0.0535 0.141
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0013 0.0015
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0207 0.0376
Plasmodium vivax tubulin gamma chain, putative 0.0804 0.3255 0.5967
Schistosoma mansoni tyrosine kinase 0.0101 0.0355 0.0651
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0058 0.018 0.033
Schistosoma mansoni tubulin subunit epsilon 0.0803 0.3251 0.5966
Leishmania major cathepsin L-like protease 0.0065 0.0207 0.0376
Brugia malayi Steroid receptor seven-up type 2 0.01 0.0353 0.0644
Echinococcus granulosus tyrosine protein kinase Src64B 0.0049 0.014 0.0254
Schistosoma mansoni organic anion transporter 0.0057 0.0173 0.0317
Echinococcus multilocularis integrin alpha ps 0.0033 0.0077 0.0075
Loa Loa (eye worm) tubulin alpha chain 0.0999 0.406 0.7449
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0044 0.0119 0.0214
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0047 0.0134 0.0132
Echinococcus multilocularis tubulin alpha chain 0.0999 0.406 0.4058
Onchocerca volvulus 0.0145 0.0535 0.2828
Schistosoma mansoni tyrosine kinase 0.0049 0.014 0.0258
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0039 0.0099 0.0181
Loa Loa (eye worm) MH2 domain-containing protein 0.0024 0.004 0.0069
Echinococcus granulosus histone acetyltransferase KAT2B 0.0044 0.0119 0.0214
Loa Loa (eye worm) MH1 domain-containing protein 0.0024 0.004 0.0069
Brugia malayi Myosin head containing protein 0.003 0.0063 0.0112
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.001
Echinococcus multilocularis c src tyrosine kinase 0.0019 0.0018 0.0016
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0008 0.001
Giardia lamblia Delta tubulin 0.0343 0.1355 0.2475
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0052 0.0092
Echinococcus granulosus beta tubulin 0.1336 0.545 1
Schistosoma mansoni tubulin subunit beta 0.1336 0.545 1
Leishmania major beta tubulin 0.1336 0.545 1
Trypanosoma brucei epsilon tubulin 0.0803 0.3251 0.5965
Leishmania major delta tubulin, putative 0.0679 0.2742 0.503
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0047 0.0134 0.0246
Trypanosoma cruzi zeta tubulin, putative 0.0905 0.3674 0.6741
Loa Loa (eye worm) hypothetical protein 0.0047 0.0134 0.0242
Echinococcus multilocularis tubulin, beta 4A class IVa 0.1336 0.545 0.5449
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0019 0.0018 0.0029
Loa Loa (eye worm) hypothetical protein 0.003 0.0063 0.0112
Schistosoma mansoni steroid hormone receptor ad4bp 0.01 0.0353 0.0647
Schistosoma mansoni tyrosine kinase 0.0161 0.0605 0.1109
Loa Loa (eye worm) tubulin beta-2A chain 0.1336 0.545 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0207 0.0376
Loa Loa (eye worm) hypothetical protein 0.0018 0.0013 0.002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0207 0.0376
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0021 0.0027 0.0025
Onchocerca volvulus 0.0027 0.0052 0.0231
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.01 0.0353 0.0644
Schistosoma mansoni hypothetical protein 0.0048 0.0139 0.0254
Loa Loa (eye worm) tubulin beta-4 chain 0.1336 0.545 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0038 0.0067
Loa Loa (eye worm) hypothetical protein 0.0057 0.0173 0.0314
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0137 0.0248
Echinococcus granulosus sterol regulatory element binding protein 0.0214 0.082 0.1501
Echinococcus multilocularis tumor protein p63 0.0344 0.1358 0.1356
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.01 0.0353 0.0644
Onchocerca volvulus Putative organic anion transporter 0.0057 0.0173 0.0881
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0009 0.0013
Trichomonas vaginalis esterase, putative 0.0145 0.0535 0.0979
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0111 0.0395 0.0725
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0104 0.0367 0.067
Echinococcus multilocularis Immunoglobulin 0.0021 0.0027 0.0025
Loa Loa (eye worm) hypothetical protein 0.01 0.0353 0.0644
Plasmodium vivax vivapain-2 0.0017 0.0009 0.0003
Brugia malayi hypothetical protein 0.0057 0.0173 0.0314
Schistosoma mansoni nephrin 0.0027 0.0051 0.0094
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0029 0.0059 0.0104
Echinococcus multilocularis integrin alpha ps 0.007 0.0227 0.0225
Echinococcus granulosus Tubulin alpha 1 chain 0.0999 0.406 0.7449
Echinococcus granulosus tubulin alpha chain 0.0999 0.406 0.7449
Loa Loa (eye worm) hypothetical protein 0.003 0.0063 0.0112
Schistosoma mansoni hypothetical protein 0.0416 0.1656 0.3039
Brugia malayi Tubulin gamma chain 0.0804 0.3255 0.5971
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0111 0.0395 0.0393
Loa Loa (eye worm) hypothetical protein 0.0145 0.0535 0.0979
Loa Loa (eye worm) hypothetical protein 0.0047 0.0134 0.0242
Schistosoma mansoni integrin alpha 0.0156 0.0581 0.1066
Echinococcus multilocularis protein dispatched 1 0.0244 0.0944 0.0942
Onchocerca volvulus 0.0058 0.0178 0.0906
Trichomonas vaginalis tubulin epsilon chain, putative 0.0999 0.406 0.7449
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0127 0.023
Brugia malayi nuclear hormone receptor family member nhr-6 0.0047 0.0134 0.0242
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0207 0.0376
Trichomonas vaginalis penicillin-binding protein, putative 0.0145 0.0535 0.0979
Schistosoma mansoni smad1 5 8 and 0.0024 0.004 0.0073
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.01 0.0353 0.0644
Loa Loa (eye worm) patched family protein 0.003 0.0063 0.0112
Toxoplasma gondii beta-tubulin, putative 0.1336 0.545 1
Trypanosoma brucei trypanothione reductase 0.0048 0.0137 0.0248
Echinococcus granulosus tyrosine protein kinase Fyn 0.0049 0.014 0.0254
Loa Loa (eye worm) hypothetical protein 0.0024 0.0039 0.0067
Leishmania major beta tubulin 0.1336 0.545 1
Loa Loa (eye worm) tubulin beta-1 chain 0.1336 0.545 1
Schistosoma mansoni tyrosine kinase 0.0101 0.0355 0.0651
Echinococcus granulosus integrin beta 2 0.0236 0.0913 0.1672
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0049 0.014 0.0138
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0049 0.014 0.0138
Brugia malayi hypothetical protein 0.003 0.0063 0.0112
Brugia malayi Cathepsin L-like precursor 0.0017 0.0009 0.0013
Schistosoma mansoni integrin alpha-ps 0.007 0.0227 0.0416
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0059 0.0108
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0029 0.0059 0.0104
Onchocerca volvulus 0.0057 0.0173 0.0881
Echinococcus multilocularis peroxisome assembly protein 26 0.0999 0.406 0.4058
Trichomonas vaginalis tubulin alpha chain, putative 0.0406 0.1614 0.2959
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0092 0.032 0.0584
Trypanosoma cruzi beta tubulin, putative 0.1336 0.545 1
Echinococcus granulosus ubiquitin specific protease 41 0.0038 0.0094 0.0169
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0058 0.018 0.0326
Trypanosoma cruzi cysteine peptidase, putative 0.0065 0.0207 0.0376
Loa Loa (eye worm) steroid hormone receptor 0.01 0.0353 0.0644
Entamoeba histolytica hypothetical protein 0.0073 0.0242 0.0444
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0009 0.0013
Schistosoma mansoni hypothetical protein 0.0048 0.0139 0.0254
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0029 0.0059 0.0057
Onchocerca volvulus 0.003 0.0063 0.0291
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0137 0.0347
Loa Loa (eye worm) TK protein kinase 0.0035 0.0084 0.0151
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0046 0.0127 0.0234
Entamoeba histolytica recQ family helicase, putative 0.0032 0.007 0.0128
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0039 0.0099 0.0177
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0048 0.0139 0.0137
Brugia malayi Patched family protein 0.003 0.0063 0.0112
Echinococcus granulosus tyrosine protein kinase Fyn 0.0049 0.014 0.0254
Brugia malayi prostaglandin transporter 0.0057 0.0173 0.0314
Loa Loa (eye worm) hypothetical protein 0.0047 0.0134 0.0242
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0067 0.0216 0.0396
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0049 0.014 0.0138
Schistosoma mansoni agrin 0.0039 0.0099 0.0181
Echinococcus granulosus follistatin 0.0039 0.0099 0.0177
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.0025 0.0041 0.0091
Onchocerca volvulus 0.0037 0.009 0.0435
Giardia lamblia Sgs1 DNA helicase, putative 0.0029 0.0059 0.0094
Echinococcus multilocularis tubulin alpha 1C chain 0.0999 0.406 0.4058
Echinococcus multilocularis transfer RNA-Lys 0.0037 0.009 0.0088
Loa Loa (eye worm) hypothetical protein 0.0039 0.0099 0.0177
Brugia malayi Tubulin beta chain 0.0406 0.1614 0.2959
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0067 0.0216 0.0214
Trichomonas vaginalis tubulin gamma chain, putative 0.0803 0.3251 0.5965
Schistosoma mansoni tyrosine kinase 0.0019 0.0018 0.0033
Leishmania major beta tubulin 0.1336 0.545 1
Echinococcus multilocularis 0.0094 0.0326 0.0324
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0009 0.0013
Mycobacterium leprae conserved hypothetical protein 0.0048 0.0136 0.074
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0089 0.0159
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0264 0.1029 0.1886
Loa Loa (eye worm) hypothetical protein 0.0057 0.0173 0.0314
Loa Loa (eye worm) MH2 domain-containing protein 0.0359 0.142 0.2603
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.01 0.0353 0.1847
Trichomonas vaginalis tubulin alpha chain, putative 0.0406 0.1614 0.2959
Brugia malayi Immunoglobulin I-set domain containing protein 0.0024 0.0039 0.0067
Trypanosoma brucei alpha tubulin 0.0999 0.406 0.7449
Schistosoma mansoni nuclear hormone receptor 0.0047 0.0134 0.0246
Leishmania major beta tubulin 0.1336 0.545 1
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.011 0.0392 0.1026
Loa Loa (eye worm) patched family protein 0.003 0.0063 0.0112
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.032 0.0584
Echinococcus granulosus Nuclear hormone receptor HR96 0.0047 0.0134 0.0242
Loa Loa (eye worm) TK/EGFR protein kinase 0.0307 0.1207 0.2212
Mycobacterium ulcerans glutaminase 0.0287 0.1122 0.8275
Trichomonas vaginalis bromodomain-containing protein, putative 0.0044 0.0119 0.0214
Brugia malayi Nuclear hormone receptor family member nhr-1 0.01 0.0353 0.0644
Loa Loa (eye worm) phosphatidylinositol 3 0.0046 0.0127 0.023
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0038 0.0094 0.0173
Schistosoma mansoni smad1 5 8 and 0.0024 0.004 0.0073
Plasmodium falciparum ataxin-2 like protein, putative 0.0176 0.0667 0.1212
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0047 0.0134 0.0672
Brugia malayi hypothetical protein 0.0048 0.0139 0.0251
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0222 0.0856 0.0854
Echinococcus granulosus bloom syndrome protein 0.0042 0.0112 0.0201
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0207 0.0376
Echinococcus multilocularis tubulin delta chain 0.0343 0.1355 0.1353
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0094 0.0173
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0009 0.0013
Echinococcus granulosus Protein patched homolog 1 0.0214 0.082 0.1501
Echinococcus granulosus lamin 0.0027 0.0052 0.0092
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0046 0.0127 0.023
Brugia malayi hypothetical protein 0.0047 0.0134 0.0242
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0104 0.0367 0.0365
Loa Loa (eye worm) agrin synaptic family protein 0.0039 0.0099 0.0177
Echinococcus granulosus tyrosine protein kinase ABL1 0.0222 0.0856 0.1568
Schistosoma mansoni follistatin 0.0039 0.0099 0.0181
Loa Loa (eye worm) BEN-1 protein 0.1336 0.545 1
Brugia malayi Patched family protein 0.003 0.0063 0.0112
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0029 0.0059 0.0057
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0127 0.023
Loa Loa (eye worm) hypothetical protein 0.01 0.0353 0.0644
Leishmania major eukaryotic initiation factor 4a, putative 0.0025 0.0041 0.0072
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.01 0.0353 0.0644
Echinococcus granulosus tubulin alpha chain 0.0999 0.406 0.7449
Giardia lamblia Alpha-tubulin 0.0999 0.406 0.7446
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0094 0.0169
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0008 0.001
Loa Loa (eye worm) hypothetical protein 0.0027 0.005 0.0088
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.0013 0.0436
Brugia malayi intermediate filament protein 0.0027 0.0052 0.0092
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0148 0.0548 0.0546
Treponema pallidum ATP-dependent RNA helicase 0.0025 0.0041 0.0252
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0059 0.0104
Echinococcus granulosus twitchin 0.0024 0.0039 0.0068
Trypanosoma cruzi cysteine peptidase, putative 0.0065 0.0207 0.0376
Loa Loa (eye worm) hypothetical protein 0.0029 0.0059 0.0104
Schistosoma mansoni tubulin subunit beta 0.1336 0.545 1
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0104 0.0177
Entamoeba histolytica cysteine protease, putative 0.0017 0.0009 0.0017
Echinococcus granulosus Niemann Pick C1 protein 0.0711 0.2873 0.527
Brugia malayi hypothetical protein 0.0241 0.0932 0.1707
Toxoplasma gondii beta-1 tubulin, putative 0.1336 0.545 1
Schistosoma mansoni tubulin subunit alpha 0.0343 0.1355 0.2486
Entamoeba histolytica hypothetical protein 0.0048 0.0136 0.0249
Trichomonas vaginalis D-aminoacylase, putative 0.0145 0.0535 0.0979
Leishmania major cathepsin L-like protease 0.0017 0.0009 0.0013
Brugia malayi nuclear hormone receptor 0.0047 0.0134 0.0242
Loa Loa (eye worm) hypothetical protein 0.0166 0.0624 0.1142
Loa Loa (eye worm) tubulin alpha-2 chain 0.0999 0.406 0.7449
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0029 0.0059 0.0094
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0128 0.0467 0.0854
Brugia malayi Nuclear hormone receptor E75 0.0047 0.0134 0.0242
Trichomonas vaginalis glucosylceramidase, putative 0.0264 0.1029 0.1886
Loa Loa (eye worm) hypothetical protein 0.0047 0.0134 0.0242
Trichomonas vaginalis tubulin, putative 0.1336 0.545 1
Trichomonas vaginalis tubulin beta chain, putative 0.0406 0.1614 0.2959
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0122 0.0442 0.3068
Echinococcus granulosus defective proboscis extension response 0.0021 0.0027 0.0045
Leishmania major alpha tubulin 0.0999 0.406 0.7449
Schistosoma mansoni hypothetical protein 0.0105 0.037 0.068
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0047 0.0134 0.0132
Leishmania major phosphopantetheinyl transferase-like protein 0.0048 0.0136 0.0245
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0057 0.0173 0.0314
Echinococcus granulosus cathepsin l cysteine peptidase 0.0017 0.0009 0.0013
Onchocerca volvulus 0.003 0.0063 0.0291
Brugia malayi Tubulin alpha chain 0.0999 0.406 0.7449
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0008 0.001
Loa Loa (eye worm) hypothetical protein 0.003 0.0063 0.0112
Trypanosoma cruzi PAB1-binding protein , putative 0.0176 0.0667 0.1221
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0654 0.1197
Loa Loa (eye worm) hypothetical protein 0.0018 0.0013 0.002
Loa Loa (eye worm) TK/INSR protein kinase 0.0101 0.0355 0.0648
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.004 0.0071
Loa Loa (eye worm) hypothetical protein 0.0118 0.0424 0.0775
Trypanosoma cruzi cysteine peptidase, putative 0.0065 0.0207 0.0376
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0059 0.0104
Brugia malayi Patched family protein 0.003 0.0063 0.0112
Schistosoma mansoni cpg binding protein 0.0061 0.0191 0.0351
Schistosoma mansoni tubulin subunit alpha 0.0999 0.406 0.7449
Onchocerca volvulus 0.0468 0.1869 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0079 0.0141
Trypanosoma brucei tubulin delta chain 0.0679 0.2742 0.503
Trypanosoma brucei beta tubulin 0.1336 0.545 1
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0145 0.0535 0.3917
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0146 0.0269
Mycobacterium leprae cell division protein FtsZ 0.0343 0.1355 1
Loa Loa (eye worm) hypothetical protein 0.0145 0.0535 0.0979
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0207 0.0376
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.001
Trichomonas vaginalis tubulin gamma chain, putative 0.0343 0.1355 0.2483
Echinococcus multilocularis lamin 0.0027 0.0052 0.005
Loa Loa (eye worm) tubulin alpha 2 0.0656 0.2644 0.4849
Echinococcus granulosus nuclear receptor 2DBD gamma 0.01 0.0353 0.0644
Brugia malayi eukaryotic initiation factor 4A 0.0025 0.0041 0.0072
Echinococcus multilocularis roundabout 2 0.003 0.0064 0.0062
Brugia malayi glutathione reductase 0.0048 0.0137 0.0248
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0039 0.0099 0.0177
Loa Loa (eye worm) hypothetical protein 0.003 0.0063 0.0112
Onchocerca volvulus 0.003 0.0063 0.0291
Brugia malayi tailless protein 0.0047 0.0134 0.0242
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0047 0.0134 0.0242
Echinococcus granulosus beta LACTamase domain containing family member 0.0145 0.0535 0.0979
Mycobacterium tuberculosis Probable reductase 0.011 0.0392 0.1026
Trypanosoma brucei epsilon tubulin 0.0803 0.3251 0.5965
Schistosoma mansoni nuclear receptor 0.0047 0.0134 0.0246
Onchocerca volvulus 0.0145 0.0535 0.2828
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0008 0.001
Brugia malayi Nuclear hormone receptor E75 0.0047 0.0134 0.0242
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0046 0.0127 0.023
Onchocerca volvulus 0.0057 0.0173 0.0881
Loa Loa (eye worm) hypothetical protein 0.01 0.0353 0.0644
Schistosoma mansoni hypothetical protein 0.0048 0.0139 0.0254
Echinococcus granulosus tyrosine protein kinase Blk 0.0042 0.0113 0.0203
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0058 0.018 0.1277
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0654 0.1197
Brugia malayi nuclear hormone receptor 0.01 0.0353 0.0644
Loa Loa (eye worm) hypothetical protein 0.003 0.0063 0.0112
Trichomonas vaginalis glucosylceramidase, putative 0.0264 0.1029 0.1886
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0009 0.0013
Plasmodium falciparum thioredoxin reductase 0.0048 0.0137 0.0238
Loa Loa (eye worm) hypothetical protein 0.003 0.0063 0.0112
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0216 0.0393
Brugia malayi Nuclear hormone receptor family member nhr-25 0.01 0.0353 0.0644
Mycobacterium ulcerans esterase/lipase LipP 0.0145 0.0535 0.3917
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0008 0.001
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0057 0.0173 0.0171
Plasmodium falciparum glutathione reductase 0.0048 0.0137 0.0238
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0048 0.0136 0.0342
Loa Loa (eye worm) hypoxia-induced factor 1 0.0153 0.0571 0.1044
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0017 0.0009 0.0013
Loa Loa (eye worm) hypothetical protein 0.003 0.0063 0.0112
Entamoeba histolytica hypothetical protein 0.0073 0.0242 0.0444
Schistosoma mansoni tubulin subunit beta 0.1336 0.545 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.01 0.0353 0.0647
Leishmania major beta tubulin 0.1336 0.545 1
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0009 0.0017
Schistosoma mansoni tubulin subunit alpha 0.0999 0.406 0.7449
Brugia malayi Nuclear hormone receptor-like 1 0.01 0.0353 0.0644
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0153 0.057 0.1043
Loa Loa (eye worm) hypothetical protein 0.01 0.0353 0.0644
Plasmodium vivax tubulin alpha chain, putative 0.0999 0.406 0.7446
Mycobacterium tuberculosis Cell division protein FtsZ 0.0343 0.1355 0.36
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0048 0.0139 0.0251
Schistosoma mansoni intermediate filament proteins 0.0027 0.0052 0.0095
Echinococcus multilocularis Tubulin alpha 1 chain 0.0999 0.406 0.4058
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0593 0.2384 0.4373
Plasmodium vivax hypothetical protein, conserved 0.0145 0.0535 0.097
Mycobacterium ulcerans hypothetical protein 0.0024 0.0038 0.0228
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.005 0.0089
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0207 0.0376
Echinococcus granulosus nuclear receptor 2DBD gamma 0.01 0.0353 0.0644
Mycobacterium ulcerans putative regulatory protein 0.0037 0.009 0.0612
Echinococcus multilocularis insulin receptor 0.0101 0.0355 0.0353
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0025 0.0041 0.0076
Brugia malayi F/Y-rich N-terminus family protein 0.0018 0.0012 0.0018
Echinococcus granulosus thyroid hormone receptor alpha 0.0047 0.0134 0.0242
Echinococcus granulosus Tubulin alpha 1 chain 0.0999 0.406 0.7449
Loa Loa (eye worm) hypothetical protein 0.0057 0.0173 0.0314
Echinococcus multilocularis survival motor neuron protein 1 0.0241 0.0932 0.093
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0044 0.0119 0.0204
Echinococcus granulosus integrin alpha 3 0.0119 0.0431 0.0787
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0061 0.0109
Echinococcus granulosus tubulin beta 1 chain 0.1336 0.545 1
Loa Loa (eye worm) alpha-tubulin 0.0999 0.406 0.7449
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0008 0.001
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0141 0.0256
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0017 0.0028
Echinococcus granulosus cathepsin L cysteine proteinase 0.0017 0.0009 0.0013
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0145 0.0535 0.0979
Loa Loa (eye worm) hypothetical protein 0.0122 0.0443 0.0809
Mycobacterium tuberculosis Probable hydrolase 0.0145 0.0535 0.141
Echinococcus granulosus insulin receptor 0.0101 0.0355 0.0648
Trypanosoma cruzi PAB1-binding protein , putative 0.0176 0.0667 0.1221
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0009 0.0013
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0008 0.0014
Echinococcus granulosus cathepsin l1 0.0017 0.0009 0.0013
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0693 0.1268
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0089 0.0159
Giardia lamblia Beta tubulin 0.1336 0.545 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0038 0.0067
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0009 0.0004
Toxoplasma gondii histone lysine methyltransferase SET1 0.0113 0.0406 0.0745
Brugia malayi MH2 domain containing protein 0.0024 0.004 0.0069
Plasmodium vivax patched family protein, putative 0.003 0.0063 0.0102
Onchocerca volvulus 0.0027 0.0052 0.0231
Loa Loa (eye worm) hypothetical protein 0.003 0.0063 0.0112
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0122 0.0442 0.1162
Echinococcus multilocularis tubulin epsilon chain 0.0803 0.3251 0.325
Loa Loa (eye worm) fibroinase 0.0017 0.0009 0.0013
Schistosoma mansoni cell adhesion molecule 0.0027 0.0051 0.0094
Schistosoma mansoni hypothetical protein 0.0033 0.0077 0.0141
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0047 0.0134 0.0242
Brugia malayi Patched family protein 0.003 0.0063 0.0112
Brugia malayi hypoxia-induced factor 1 0.0153 0.0571 0.1044
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0094 0.0169
Brugia malayi Nuclear hormone receptor family member nhr-41 0.01 0.0353 0.0644
Schistosoma mansoni smad 0.0024 0.004 0.0073
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0048 0.0136 0.0951
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.01 0.0353 0.0644
Echinococcus granulosus tm gpcr rhodopsin 0.0538 0.2158 0.3959
Loa Loa (eye worm) hypothetical protein 0.0241 0.0932 0.1707
Echinococcus granulosus Tubulin beta 2C chain 0.1336 0.545 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0058 0.018 0.1277
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.011 0.0392 0.2684
Loa Loa (eye worm) hypothetical protein 0.003 0.0063 0.0112
Onchocerca volvulus 0.0145 0.0535 0.2828
Loa Loa (eye worm) hypothetical protein 0.0028 0.0053 0.0093
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0264 0.1029 0.1886
Brugia malayi Nuclear hormone receptor family member nhr-49 0.01 0.0353 0.0644
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.032 0.0318
Trichomonas vaginalis tubulin alpha chain, putative 0.0406 0.1614 0.2959
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.011 0.0392 0.1026
Echinococcus granulosus ecdysone induced protein 78C 0.01 0.0353 0.0644
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.001
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0013 0.0041
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0046 0.0127 0.0234
Brugia malayi Nuclear hormone receptor family member nhr-19 0.01 0.0353 0.0644
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.01 0.018
Echinococcus multilocularis bloom syndrome protein 0.0042 0.0112 0.011
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0094 0.0169
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.01 0.0353 0.0644
Leishmania major beta tubulin 0.1336 0.545 1
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0048 0.0136 0.0951
Schistosoma mansoni thyroid hormone receptor 0.0228 0.0881 0.1617
Schistosoma mansoni alpha tubulin 0.0999 0.406 0.7449
Loa Loa (eye worm) hypothetical protein 0.0048 0.0139 0.0251
Loa Loa (eye worm) hypothetical protein 0.0053 0.0157 0.0285
Schistosoma mansoni zinc finger protein 0.0047 0.0134 0.0246
Entamoeba histolytica tubulin alpha-1 chain 0.0999 0.406 0.7449
Schistosoma mansoni tyrosine kinase 0.0106 0.0376 0.0689
Loa Loa (eye worm) hypothetical protein 0.003 0.0063 0.0112
Echinococcus multilocularis Tubulin beta 2C chain 0.1336 0.545 0.5449
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0048 0.0139 0.0251
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0047 0.0134 0.0132
Echinococcus multilocularis neuroglian 0.0024 0.0039 0.0037
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0406 0.1614 0.2959
Loa Loa (eye worm) hypothetical protein 0.01 0.0353 0.0644
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0024 0.004 0.0038
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0044 0.0119 0.0218
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0111 0.0395 0.1036
Giardia lamblia Epsilon tubulin 0.0397 0.1576 0.2882
Loa Loa (eye worm) hypothetical protein 0.003 0.0063 0.0112
Loa Loa (eye worm) beta-tubulin 0.1336 0.545 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.0047 0.0134 0.0242
Mycobacterium tuberculosis Probable esterase LipL 0.0145 0.0535 0.141
Brugia malayi Calcitonin receptor-like protein seb-1 0.0153 0.057 0.1043
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.01 0.0353 0.0351
Loa Loa (eye worm) hypothetical protein 0.0018 0.0013 0.002
Echinococcus granulosus c src tyrosine kinase 0.0019 0.0018 0.0029
Leishmania major gamma-tubulin 0.0804 0.3255 0.5971
Loa Loa (eye worm) hypothetical protein 0.0047 0.0134 0.0242
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0111 0.0395 0.0722
Trichomonas vaginalis tubulin epsilon chain, putative 0.1336 0.545 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.01 0.0353 0.0644
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0137 0.0238
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0047 0.0134 0.0672
Mycobacterium tuberculosis Probable lipase LipE 0.0145 0.0535 0.141
Toxoplasma gondii isocitrate dehydrogenase 0.0111 0.0395 0.0725
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0009 0.0004
Trypanosoma brucei alpha tubulin 0.0999 0.406 0.7449
Toxoplasma gondii alpha-tubulin I, putative 0.0999 0.406 0.7449
Leishmania major alpha tubulin 0.0999 0.406 0.7449
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0104 0.019
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.01 0.0353 0.0647
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0094 0.0092
Echinococcus multilocularis tubulin gamma 1 chain 0.0804 0.3255 0.3253
Echinococcus multilocularis tubulin alpha 3 chain 0.0999 0.406 0.4058
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0538 0.2158 0.2157
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0009 0.0013
Loa Loa (eye worm) hypothetical protein 0.0086 0.0293 0.0534
Echinococcus granulosus agrin 0.0039 0.0099 0.0177
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0025 0.0041 0.0072
Trichomonas vaginalis DNA helicase recq1, putative 0.0042 0.0112 0.0201
Loa Loa (eye worm) tubulin beta chain 0.0343 0.1355 0.2483
Toxoplasma gondii protease inhibitor PI2 0.0039 0.0099 0.0181
Brugia malayi Patched protein homolog 1 0.003 0.0063 0.0112
Trichomonas vaginalis tubulin gamma chain, putative 0.0804 0.3255 0.5971
Echinococcus granulosus Niemann Pick C1 protein 0.0498 0.1992 0.3653
Loa Loa (eye worm) hypothetical protein 0.003 0.0063 0.0112
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0052 0.0092
Echinococcus granulosus beta tubulin 0.1336 0.545 1
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0024 0.0039 0.0069
Brugia malayi Patched family protein 0.003 0.0063 0.0112
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0013 0.0019
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0008 0.001
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0038 0.0067
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0111 0.0395 0.0722
Loa Loa (eye worm) hypothetical protein 0.0053 0.0157 0.0285
Leishmania major eukaryotic initiation factor 4a, putative 0.0025 0.0041 0.0072
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.032 0.0318
Loa Loa (eye worm) hypothetical protein 0.0025 0.0041 0.0072
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0047 0.0134 0.0246
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0067 0.0216 0.0396
Onchocerca volvulus 0.003 0.0063 0.0291
Brugia malayi PAS domain containing protein 0.005 0.0143 0.0259
Schistosoma mansoni nuclear hormone receptor 0.01 0.0353 0.0647
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0207 0.0376
Echinococcus multilocularis cysteine protease 0.0017 0.0009 0.0007
Leishmania major epsilon tubulin, putative 0.0803 0.3251 0.5965
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.01 0.0353 0.0644
Trichomonas vaginalis tubulin epsilon chain, putative 0.0999 0.406 0.7449
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0051 0.0091
Mycobacterium tuberculosis Putative ferredoxin reductase 0.011 0.0392 0.1026
Schistosoma mansoni tyrosine kinase 0.0215 0.0828 0.1519
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0079 0.0141
Loa Loa (eye worm) hypothetical protein 0.0018 0.0013 0.002
Mycobacterium tuberculosis Conserved protein 0.0145 0.0535 0.141
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.01 0.0353 0.0644
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0067 0.0216 0.0393
Loa Loa (eye worm) hypothetical protein 0.0057 0.0173 0.0314
Loa Loa (eye worm) hypothetical protein 0.0053 0.0157 0.0285
Brugia malayi Smad1 0.0024 0.004 0.0069
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0008 0.001
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0008 0.001
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.0242 0.044
Echinococcus multilocularis ecdysone induced protein 78C 0.01 0.0353 0.0351
Echinococcus multilocularis expressed protein 0.0039 0.0099 0.0097
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0036 0.0089 0.016
Leishmania major alpha tubulin 0.0999 0.406 0.7449
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0999 0.406 0.7449
Echinococcus multilocularis Tubulin alpha 1 chain 0.0999 0.406 0.4058
Schistosoma mansoni DNA helicase recq5 0.0029 0.0059 0.0108
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.01 0.0353 0.0644
Echinococcus multilocularis Tubulin beta 2C chain 0.1336 0.545 0.5449
Toxoplasma gondii thioredoxin reductase 0.0048 0.0137 0.0252
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0002 0.0004
Mycobacterium ulcerans hypothetical protein 0.0145 0.0535 0.3917
Trypanosoma brucei tubulin gamma chain 0.0804 0.3255 0.5971
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0038 0.0228
Leishmania major alpha tubulin 0.0999 0.406 0.7449
Toxoplasma gondii cathepsin CPL 0.0017 0.0009 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0009 0.0013
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0038 0.007
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0167 0.0628 0.1148
Echinococcus granulosus alpha tubulin 0.0999 0.406 0.7449
Entamoeba histolytica tubulin family protein 0.1336 0.545 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0058 0.0178 0.0322
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0094 0.0169
Echinococcus multilocularis sterol regulatory element binding protein 0.0214 0.082 0.0818
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0025 0.0041 0.0072
Trichomonas vaginalis tubulin beta chain, putative 0.0999 0.406 0.7449
Loa Loa (eye worm) hypothetical protein 0.0039 0.0099 0.0177
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0025 0.0041 0.0174
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0025 0.0042 0.0063
Loa Loa (eye worm) hypothetical protein 0.0027 0.0052 0.0092
Onchocerca volvulus 0.0057 0.0173 0.0881
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0048 0.0136 0.0249
Loa Loa (eye worm) patched family protein 0.003 0.0063 0.0112
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0207 0.0376
Toxoplasma gondii tubulin, putative 0.0054 0.016 0.0294
Echinococcus multilocularis dnaJ subfamily B 0.0416 0.1656 0.1654
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0094 0.0169
Entamoeba histolytica tubulin family protein 0.1336 0.545 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0089 0.0159
Echinococcus multilocularis ubiquitin specific protease 41 0.0038 0.0094 0.0092
Loa Loa (eye worm) hypothetical protein 0.0047 0.0134 0.0242
Schistosoma mansoni RAR-like nuclear receptor 0.01 0.0353 0.0647
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0046 0.0127 0.023
Echinococcus granulosus Tubulin beta 2C chain 0.1336 0.545 1
Onchocerca volvulus 0.003 0.0063 0.0291
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0137 0.0248
Echinococcus multilocularis beta LACTamase domain containing family member 0.0145 0.0535 0.0533
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0058 0.018 0.0326
Loa Loa (eye worm) cysteine protease 0.0017 0.0009 0.0013
Schistosoma mansoni hypothetical protein 0.0206 0.0788 0.1446
Schistosoma mansoni tyrosine kinase 0.0049 0.014 0.0258
Brugia malayi Isocitrate dehydrogenase 0.0111 0.0395 0.0722
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0498 0.1992 0.3655
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0067 0.0216 0.0393
Echinococcus granulosus tubulin alpha 1C chain 0.0999 0.406 0.7449
Schistosoma mansoni hypothetical protein 0.1187 0.4834 0.8871
Loa Loa (eye worm) hypothetical protein 0.0057 0.0173 0.0314
Loa Loa (eye worm) hypothetical protein 0.003 0.0063 0.0112
Loa Loa (eye worm) hypothetical protein 0.003 0.0063 0.0112
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0048 0.0136 0.0235
Echinococcus multilocularis epidermal growth factor receptor 0.0167 0.0628 0.0626
Trypanosoma brucei beta tubulin 0.0749 0.303 0.5558
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0111 0.0395 0.0712
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0009 0.0013
Brugia malayi latrophilin 2 splice variant baaae 0.0105 0.037 0.0676
Echinococcus multilocularis hypothetical protein 0.0999 0.406 0.4058
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0654 0.1197
Leishmania major alpha tubulin 0.0999 0.406 0.7449
Loa Loa (eye worm) ctsf protein 0.0017 0.0009 0.0013
Brugia malayi protein-tyrosine kinase 0.0042 0.0113 0.0203
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0094 0.0169
Echinococcus granulosus histone acetyltransferase KAT2B 0.0144 0.0534 0.0976
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0058 0.018 0.0178
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0037 0.009 0.0088
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0094 0.0169
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0049 0.014 0.0254
Toxoplasma gondii patched family protein 0.003 0.0063 0.0116
Echinococcus granulosus Tubulin beta 2C chain 0.1336 0.545 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.01 0.0353 0.0351
Loa Loa (eye worm) hypothetical protein 0.0053 0.0157 0.0285
Echinococcus granulosus neuropeptide s receptor 0.0479 0.1917 0.3515
Brugia malayi bHLH-PAS transcription factor 0.0037 0.009 0.0161
Brugia malayi MH1 domain containing protein 0.0024 0.004 0.0069
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0148 0.0551 0.1011
Loa Loa (eye worm) hypothetical protein 0.0047 0.0134 0.0242
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0216 0.0393
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0009 0.0013
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0099 0.0178
Brugia malayi conserved hypotetical protein 0.0047 0.0134 0.0242
Loa Loa (eye worm) tubulin alpha-3 chain 0.0593 0.2384 0.4373
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0106 0.0376 0.0374
Echinococcus granulosus integrin alpha ps 0.007 0.0227 0.0412
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0046 0.0127 0.023
Schistosoma mansoni hypothetical protein 0.0206 0.0788 0.1446
Loa Loa (eye worm) hypothetical protein 0.0047 0.0134 0.0242
Loa Loa (eye worm) beta-lactamase 0.0145 0.0535 0.0979
Echinococcus granulosus tubulin alpha chain 0.0999 0.406 0.7449
Echinococcus granulosus tubulin delta chain 0.0343 0.1355 0.2483
Echinococcus multilocularis tubulin subunit beta 0.1336 0.545 0.5449
Trichomonas vaginalis tubulin epsilon chain, putative 0.0343 0.1355 0.2483
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0079 0.0141
Loa Loa (eye worm) hypothetical protein 0.0024 0.0038 0.0067
Echinococcus granulosus expressed conserved protein 0.0467 0.1867 0.3424
Brugia malayi hypothetical protein 0.0468 0.1869 0.3428
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0654 0.1197
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0039 0.0099 0.0181
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0036 0.0089 0.016
Trypanosoma cruzi tubulin delta chain 0.0679 0.2742 0.503
Echinococcus granulosus nuclear receptor nhr 48 0.0047 0.0134 0.0242
Echinococcus multilocularis tubulin alpha chain 0.0999 0.406 0.4058
Trichomonas vaginalis DNA helicase recq, putative 0.0032 0.007 0.0124
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0008 0.001
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0008 0.0014
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0009 0.0007
Trichomonas vaginalis tubulin, putative 0.0398 0.1579 0.2895
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0039 0.0101 0.0171
Schistosoma mansoni tyrosine kinase 0.0167 0.0628 0.1152
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.032 0.0584
Trichomonas vaginalis DNA helicase recq, putative 0.0042 0.0112 0.0201
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0009 0.0013
Brugia malayi Tubulin beta chain 0.0343 0.1355 0.2483
Brugia malayi steroid hormone receptor 0.01 0.0353 0.0644
Schistosoma mansoni tyrosine kinase 0.0307 0.1207 0.2215
Echinococcus granulosus tyrosine protein kinase Src42A 0.0037 0.009 0.0161
Echinococcus granulosus L aminoadipate semialdehyde 0.017 0.0639 0.1169
Loa Loa (eye worm) patched family protein 0.003 0.0063 0.0112
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.011 0.0392 0.1026
Plasmodium vivax tubulin alpha chain, putative 0.0999 0.406 0.7446
Trypanosoma brucei alpha tubulin 0.0999 0.406 0.7449
Brugia malayi glutaminase DH11.1 0.0287 0.1122 0.2056
Brugia malayi Nuclear hormone receptor-like 1 0.0053 0.0157 0.0285
Brugia malayi protein C24B5.3 0.003 0.0063 0.0112
Echinococcus multilocularis tyrosine protein kinase HCK 0.0035 0.0084 0.0082
Entamoeba histolytica hypothetical protein 0.0073 0.0242 0.0444
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0051 0.0091
Onchocerca volvulus 0.017 0.0639 0.3386
Echinococcus multilocularis cysteine protease 0.0017 0.0009 0.0007
Schistosoma mansoni tubulin subunit beta 0.0343 0.1355 0.2486
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0059 0.0183 0.0333
Trichomonas vaginalis penicillin-binding protein, putative 0.0145 0.0535 0.0979
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0009 0.0013
Leishmania major beta tubulin 0.1336 0.545 1
Loa Loa (eye worm) integrin alpha pat-2 0.024 0.0929 0.1701
Brugia malayi protein C24B5.3 0.003 0.0063 0.0112
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0693 0.1268
Loa Loa (eye worm) hypothetical protein 0.003 0.0063 0.0112
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0038 0.0228
Brugia malayi CHE-14 protein 0.0214 0.082 0.1501
Brugia malayi Thioredoxin reductase 0.0048 0.0137 0.0248
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.0654 0.1197
Brugia malayi Patched family protein 0.003 0.0063 0.0112
Trichomonas vaginalis conserved hypothetical protein 0.0214 0.082 0.1501
Brugia malayi Tubulin beta-1 chain 0.1336 0.545 1
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0046 0.0127 0.0234
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0038 0.0094 0.0159
Brugia malayi sulfakinin receptor protein 0.0227 0.0877 0.1606
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.032 0.0588
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0025 0.0041 0.0076
Toxoplasma gondii patched family protein 0.003 0.0063 0.0116
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0009 0.0013
Brugia malayi Niemann-Pick C1 protein precursor 0.0498 0.1992 0.3653
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0137 0.0135
Leishmania major alpha tubulin 0.0999 0.406 0.7449
Schistosoma mansoni smad1 5 8 and 0.0024 0.004 0.0073
Brugia malayi Nuclear hormone receptor family member nhr-3 0.01 0.0353 0.0644
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0009 0.0013
Brugia malayi nuclear receptor NHR-67 0.0047 0.0134 0.0242
Leishmania major beta tubulin 0.1336 0.545 1
Echinococcus multilocularis tyrosine protein kinase Srms 0.0042 0.0113 0.0111
Giardia lamblia Alpha-tubulin 0.0999 0.406 0.7446
Entamoeba histolytica protein kinase, putative 0.0035 0.0084 0.0155
Echinococcus granulosus survival motor neuron protein 1 0.0241 0.0932 0.1707
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0749 0.303 0.556
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0057 0.0173 0.0314
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0013 0.001
Schistosoma mansoni retinoic acid receptor RXR 0.0201 0.0767 0.1407
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0009 0.0013
Trichomonas vaginalis tubulin beta chain, putative 0.0999 0.406 0.7449
Echinococcus multilocularis isocitrate dehydrogenase 0.0111 0.0395 0.0393
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0079 0.0265 0.0483
Loa Loa (eye worm) hypothetical protein 0.0027 0.0052 0.0091
Trichomonas vaginalis tubulin beta chain, putative 0.1336 0.545 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.004 0.0071
Schistosoma mansoni glutaminase 0.0287 0.1122 0.2059
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0038 0.0067
Echinococcus granulosus neuroglian 0.0024 0.0039 0.0068
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0038 0.0094 0.0173
Brugia malayi Nuclear hormone receptor family member nhr-31 0.01 0.0353 0.0644
Loa Loa (eye worm) histone methyltransferase 0.0018 0.0013 0.0019
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0032 0.007 0.0124
Trypanosoma brucei beta tubulin 0.1336 0.545 1
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0048 0.0136 0.0951
Trypanosoma cruzi epsilon tubulin, putative 0.0803 0.3251 0.5965
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0025 0.0041 0.0039
Loa Loa (eye worm) hypothetical protein 0.0024 0.0039 0.0067
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0029 0.0059 0.0104
Onchocerca volvulus 0.0047 0.0134 0.0672
Onchocerca volvulus 0.0057 0.0173 0.0881
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0019 0.0018 0.0016
Brugia malayi Patched family protein 0.003 0.0063 0.0112
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0038 0.007
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0106 0.0376 0.0374
Echinococcus granulosus eukaryotic initiation factor 4A 0.0025 0.0041 0.0072
Treponema pallidum cell division protein FtsZ 0.0343 0.1355 1
Plasmodium falciparum alpha tubulin 1 0.0999 0.406 0.7446
Brugia malayi Integrin alpha pat-2 precursor 0.0156 0.0581 0.1063
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0049 0.014 0.0254
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0106 0.0376 0.0686
Brugia malayi hypothetical protein 0.0057 0.0173 0.0314
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0009 0.0013
Loa Loa (eye worm) BEN-1 protein 0.1336 0.545 1
Schistosoma mansoni tubulin subunit delta 0.0343 0.1355 0.2486
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0038 0.0067
Echinococcus multilocularis cpg binding protein 0.0061 0.0191 0.0189
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0137 0.0248
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0009 0.0013
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0009 0.0013
Brugia malayi Cathepsin L-like precursor 0.0017 0.0009 0.0013
Echinococcus multilocularis beta tubulin 0.1336 0.545 0.5449
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0679 0.2742 0.5032
Loa Loa (eye worm) hypothetical protein 0.0021 0.0027 0.0045
Brugia malayi Nuclear hormone receptor family member nhr-25 0.01 0.0353 0.0644
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0046 0.0127 0.0125
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0111 0.0395 0.0393
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0009 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0079 0.0141
Loa Loa (eye worm) hypothetical protein 0.005 0.0146 0.0265
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0656 0.2644 0.4849
Brugia malayi Cathepsin L-like precursor 0.0017 0.0009 0.0013
Echinococcus granulosus tubulin alpha 0.0749 0.303 0.5558
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0054 0.0163 0.0296
Schistosoma mansoni vesicular amine transporter 0.0021 0.0027 0.0049
Brugia malayi tubulin alpha-2 chain 0.0999 0.406 0.7449
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0048 0.0139 0.0137
Onchocerca volvulus Putative organic anion transporter 0.0057 0.0173 0.0881
Onchocerca volvulus Bile acid receptor homolog 0.01 0.0353 0.1847
Onchocerca volvulus 0.003 0.0063 0.0291
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0025 0.0041 0.0076
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0009 0.0013
Loa Loa (eye worm) hypothetical protein 0.0047 0.0134 0.0242
Toxoplasma gondii patched family protein 0.003 0.0063 0.0116
Brugia malayi hypothetical protein 0.003 0.0063 0.0112
Schistosoma mansoni cpg binding protein 0.0058 0.0178 0.0326
Echinococcus multilocularis neuropeptide receptor A26 0.0479 0.1917 0.1915
Plasmodium falciparum tubulin gamma chain 0.0804 0.3255 0.5967
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0009 0.0004
Loa Loa (eye worm) hypothetical protein 0.0145 0.0535 0.0979
Toxoplasma gondii isocitrate dehydrogenase 0.0111 0.0395 0.0725
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0009 0.0013
Brugia malayi Cathepsin L-like precursor 0.0017 0.0009 0.0013
Echinococcus granulosus tumor protein p63 0.0344 0.1358 0.2488
Loa Loa (eye worm) glutaminase 2 0.0287 0.1122 0.2056
Brugia malayi Patched family protein 0.003 0.0063 0.0112
Loa Loa (eye worm) tubulin gamma chain 0.0804 0.3255 0.5971
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0025 0.0041 0.0072
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0924 0.3749 1
Trypanosoma brucei epsilon tubulin 0.0749 0.303 0.5558
Brugia malayi hypothetical protein 0.0114 0.0409 0.0747
Schistosoma mansoni tubulin subunit beta 0.1336 0.545 1
Echinococcus multilocularis integrin alpha 3 0.0119 0.0431 0.0429
Schistosoma mansoni hypothetical protein 0.1187 0.4834 0.8871
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0048 0.0136 1
Trichomonas vaginalis conserved hypothetical protein 0.0343 0.1355 0.2483
Loa Loa (eye worm) hypothetical protein 0.003 0.0063 0.0112
Echinococcus multilocularis lamin dm0 0.0027 0.0052 0.005
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0008 0.0006
Brugia malayi hypothetical protein 0.0053 0.0157 0.0285
Loa Loa (eye worm) hypothetical protein 0.0024 0.0038 0.0067
Schistosoma mansoni hypothetical protein 0.0079 0.0265 0.0487
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0038 0.0228
Brugia malayi MH2 domain containing protein 0.0024 0.004 0.0069
Leishmania major cathepsin L-like protease 0.0017 0.0009 0.0013
Schistosoma mansoni lamin 0.0027 0.0052 0.0095
Loa Loa (eye worm) hypothetical protein 0.0105 0.037 0.0676
Echinococcus granulosus roundabout 2 0.003 0.0064 0.0114
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0094 0.0169
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0038 0.0228
Trichomonas vaginalis tubulin beta chain, putative 0.0999 0.406 0.7449
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0009 0.0004
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0009 0.0007
Echinococcus granulosus tyrosine protein kinase Fyn 0.0049 0.014 0.0254
Toxoplasma gondii transporter, major facilitator family protein 0.0057 0.0173 0.0317
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0048 0.0136 0.0951
Loa Loa (eye worm) TK/KIN16 protein kinase 0.003 0.0062 0.0111
Loa Loa (eye worm) hypothetical protein 0.0027 0.0052 0.0091
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.0242 0.0444
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0009 0.0007
Echinococcus multilocularis L aminoadipate semialdehyde 0.017 0.0639 0.0637
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.032 0.0588
Brugia malayi tubulin alpha chain - mouse 0.0999 0.406 0.7449
Loa Loa (eye worm) tubulin alpha chain 0.0999 0.406 0.7449
Echinococcus multilocularis epidermal growth factor receptor 0.0307 0.1207 0.1205
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.017 0.0639 0.1169
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0049 0.014 0.0138
Plasmodium vivax vivapain-2 0.0017 0.0009 0.0003
Echinococcus multilocularis protein patched 0.0214 0.082 0.0818
Onchocerca volvulus 0.0024 0.0038 0.0157
Echinococcus multilocularis tubulin alpha 1C chain 0.0999 0.406 0.4058
Loa Loa (eye worm) hypothetical protein 0.0057 0.0173 0.0314
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0145 0.0535 0.141
Loa Loa (eye worm) hypothetical protein 0.0024 0.0039 0.0067
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0111 0.0395 0.0393
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0065 0.0207 0.0376
Loa Loa (eye worm) hypothetical protein 0.003 0.0063 0.0112
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0397 0.1576 0.2892
Loa Loa (eye worm) hypothetical protein 0.0018 0.0013 0.002
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0092 0.032 0.0584
Loa Loa (eye worm) hypothetical protein 0.003 0.0063 0.0112
Loa Loa (eye worm) hypothetical protein 0.0017 0.0009 0.0013
Leishmania major alpha tubulin 0.0999 0.406 0.7449
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0047 0.0134 0.0242
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0008 0.001
Onchocerca volvulus Protein ultraspiracle homolog 0.01 0.0353 0.1847
Brugia malayi hypothetical protein 0.0073 0.0242 0.044
Echinococcus multilocularis beta tubulin 0.1336 0.545 0.5449
Onchocerca volvulus 0.003 0.0063 0.0291
Loa Loa (eye worm) hypothetical protein 0.0033 0.0077 0.0137
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.01 0.0353 0.0351
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0111 0.0395 0.0722
Schistosoma mansoni patched 1 0.0214 0.082 0.1504
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0049 0.014 0.0138
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0049 0.014 0.0138
Toxoplasma gondii beta tubulin 0.1336 0.545 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0038 0.0228
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0047 0.0134 0.0242
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0038 0.0067
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0038 0.0228
Echinococcus multilocularis musashi 0.0027 0.0052 0.005
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0145 0.0535 0.0982
Trichomonas vaginalis tubulin gamma chain, putative 0.1336 0.545 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0041 0.0071
Brugia malayi Patched family protein 0.003 0.0063 0.0112
Loa Loa (eye worm) transcription factor SMAD2 0.0359 0.142 0.2603
Echinococcus multilocularis nuclear receptor nhr 48 0.0047 0.0134 0.0132
Echinococcus granulosus peroxisome assembly protein 26 0.0999 0.406 0.7449
Loa Loa (eye worm) hypothetical protein 0.0021 0.0027 0.0045
Echinococcus granulosus fibroblast growth factor receptor 4 0.0106 0.0376 0.0686
Echinococcus multilocularis integrin beta 2 0.0236 0.0913 0.0911
Giardia lamblia Beta tubulin 0.1336 0.545 1
Trypanosoma cruzi zeta tubulin, putative 0.0905 0.3674 0.6741
Trichomonas vaginalis tubulin beta chain, putative 0.0999 0.406 0.7449
Brugia malayi Immunoglobulin I-set domain containing protein 0.0109 0.0388 0.0709
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0059 0.0108
Schistosoma mansoni blooms syndrome DNA helicase 0.0027 0.005 0.0092
Echinococcus multilocularis tyrosine protein kinase Abl 0.0099 0.0349 0.0347
Leishmania major trypanothione reductase 0.0048 0.0137 0.0248
Mycobacterium tuberculosis Probable lipase LipD 0.0145 0.0535 0.141
Loa Loa (eye worm) DR-78 0.0047 0.0134 0.0242
Schistosoma mansoni nuclear receptor nhr-48 0.0047 0.0134 0.0246
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0046 0.0127 0.023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.004 0.0071
Schistosoma mansoni nuclear receptor 0.0047 0.0134 0.0246
Onchocerca volvulus Putative organic anion transporter 0.0057 0.0173 0.0881
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.01 0.0353 0.0644
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0009 0.0013
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0025 0.0041 0.0072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0089 0.0159
Echinococcus multilocularis tubulin alpha chain 0.0999 0.406 0.4058
Giardia lamblia Beta tubulin 0.1336 0.545 1
Echinococcus granulosus single minded 2 0.0037 0.009 0.0161
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0041 0.0071
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0049 0.014 0.0138
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0008 0.0014
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0079 0.0265 0.0263
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0122 0.0442 0.1162
Trichomonas vaginalis D-aminoacylase, putative 0.0145 0.0535 0.0979
Brugia malayi Tubulin alpha-2 chain 0.0999 0.406 0.7449
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0039 0.0099 0.0177
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0013 0.001
Mycobacterium leprae conserved hypothetical protein 0.0145 0.0535 0.3775
Mycobacterium tuberculosis Conserved protein 0.0145 0.0535 0.141
Schistosoma mansoni thyroid hormone receptor 0.0228 0.0881 0.1617
Echinococcus granulosus integrin alpha ps 0.0033 0.0077 0.0137
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0008 0.001
Brugia malayi nuclear receptor NHR-88 0.01 0.0353 0.0644
Echinococcus multilocularis geminin 0.1187 0.4834 0.4833
Loa Loa (eye worm) TK/ABL protein kinase 0.0222 0.0856 0.1568
Echinococcus granulosus Tubulin beta 2C chain 0.1336 0.545 1
Echinococcus granulosus Tubulin alpha 1 chain 0.0999 0.406 0.7449
Brugia malayi Immunoglobulin I-set domain containing protein 0.003 0.0062 0.0111
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0065 0.0116
Leishmania major hypothetical protein, conserved 0.0145 0.0535 0.0979
Leishmania major alpha tubulin 0.0999 0.406 0.7449
Brugia malayi Tubulin alpha chain 0.0343 0.1355 0.2483
Leishmania major cathepsin L-like protease 0.0065 0.0207 0.0376
Loa Loa (eye worm) hypothetical protein 0.0176 0.0667 0.1221
Schistosoma mansoni tubulin subunit alpha 0.0999 0.406 0.7449
Loa Loa (eye worm) hypothetical protein 0.003 0.0063 0.0112
Loa Loa (eye worm) hypothetical protein 0.0145 0.0535 0.0979
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0053 0.0157 0.0285
Brugia malayi ecdysone receptor 0.0047 0.0134 0.0242
Leishmania major beta tubulin 0.1336 0.545 1
Loa Loa (eye worm) hypothetical protein 0.0498 0.1992 0.3653
Brugia malayi Cathepsin L-like precursor 0.0017 0.0009 0.0013
Brugia malayi hypothetical protein 0.0053 0.0157 0.0285
Plasmodium falciparum tubulin delta chain, putative 0.0343 0.1355 0.2475
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0099 0.0097
Trichomonas vaginalis tubulin, putative 0.0406 0.1614 0.2959
Leishmania major alpha tubulin 0.0999 0.406 0.7449
Echinococcus multilocularis thyroid hormone receptor alpha 0.0228 0.0881 0.0879
Loa Loa (eye worm) tubulin beta chain 0.1336 0.545 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0079 0.0141
Brugia malayi CXXC zinc finger family protein 0.0058 0.0178 0.0322
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0049 0.014 0.0138
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0067 0.0216 0.0393
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.01 0.0353 0.0644
Trichomonas vaginalis tubulin beta chain, putative 0.0999 0.406 0.7449
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0048 0.0136 0.0235
Brugia malayi Nuclear hormone receptor-like 1 0.0053 0.0157 0.0285
Loa Loa (eye worm) hypothetical protein 0.0021 0.0027 0.0045
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0111 0.0395 0.0722
Loa Loa (eye worm) hypothetical protein 0.01 0.0353 0.0644
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0089 0.0159
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0009 0.0013
Plasmodium falciparum tubulin epsilon chain, putative 0.0803 0.3251 0.5961
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0051 0.0091
Leishmania major beta tubulin 0.1336 0.545 1
Brugia malayi beta-lactamase family protein 0.0145 0.0535 0.0979

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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