Detailed information for compound 89411

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 681.855 | Formula: C39H55NO9
  • H donors: 1 H acceptors: 5 LogP: 6.68 Rotable bonds: 19
    Rule of 5 violations (Lipinski): 2
  • SMILES: COCC(=O)[C@@H](C[C@@H](/C=C\C=C\C=C(\[C@H](C[C@@H]1CC[C@H]([C@](O1)(O)C(=O)C(=O)N1CCCC[C@H]1C(=O)OCc1ccccc1)C)OC)/C)C)C
  • InChi: 1S/C39H55NO9/c1-27(23-29(3)34(41)26-46-5)15-9-7-10-16-28(2)35(47-6)24-32-21-20-30(4)39(45,49-32)36(42)37(43)40-22-14-13-19-33(40)38(44)48-25-31-17-11-8-12-18-31/h7-12,15-18,27,29-30,32-33,35,45H,13-14,19-26H2,1-6H3/b10-7+,15-9-,28-16+/t27-,29-,30-,32+,33+,35+,39-/m1/s1
  • InChiKey: IGDNDHZJRXIJQN-ZNNZOQJOSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0021 0.0307 0.0497
Echinococcus multilocularis protein kinase c iota type 0.0005 0.0002 0.0002
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0008 0.0057 0.0044
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0005 0.0002 0.0002
Schistosoma mansoni serine/threonine-protein kinase 0.0009 0.0075 0.0121
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0045 0.0746 0.1208
Toxoplasma gondii fructose-bisphosphate aldolase, putative 0.0029 0.045 0.1786
Schistosoma mansoni protein kinase 0.0034 0.0537 0.0869
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0397 0.0819
Loa Loa (eye worm) hypothetical protein 0.0017 0.0223 0.036
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0397 0.2017
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0009 0.0074 0.0038
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0006 0.0029 0.0046
Trypanosoma brucei unspecified product 0.0019 0.026 0.1997
Trypanosoma cruzi hypothetical protein, conserved 0.0008 0.0071 0.0486
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0144 0.257 0.2685
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0015 0.0199 0.1504
Brugia malayi Thioredoxin reductase 0.0033 0.0525 0.1084
Brugia malayi flavodoxin family protein 0.0007 0.0037 0.0074
Echinococcus multilocularis thyroid hormone receptor alpha 0.0045 0.0746 0.0779
Onchocerca volvulus 0.0045 0.0746 0.3134
Echinococcus multilocularis serine:threonine protein kinase 38 0.0005 0.0002 0.0002
Plasmodium falciparum ataxin-2 like protein, putative 0.0013 0.0146 0.0535
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0008 0.0064 0.0067
Trichomonas vaginalis AGC family protein kinase 0.0034 0.0537 0.274
Trichomonas vaginalis alpha-glucosidase, putative 0.0012 0.0141 0.072
Brugia malayi nuclear hormone receptor family member odr-7 0.0021 0.0307 0.0633
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0024 0.0354 0.0573
Toxoplasma gondii hypothetical protein 0.0029 0.0442 0.175
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0009 0.0074 0.026
Loa Loa (eye worm) hypothetical protein 0.002 0.0275 0.0445
Loa Loa (eye worm) hypothetical protein 0.0049 0.082 0.1328
Schistosoma mansoni chromobox protein 0.0024 0.0351 0.0569
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0021 0.0307 0.0497
Echinococcus multilocularis microtubule associated protein 2 0.0255 0.4608 0.4815
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0045 0.0746 0.1208
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0006 0.0029 0.0046
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0397 0.3107
Entamoeba histolytica hypothetical protein 0.0009 0.0074 0.0369
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.026 0.1997
Brugia malayi amine oxidase, flavin-containing family protein 0.0016 0.0202 0.0415
Brugia malayi hypothetical protein 0.0013 0.0146 0.0299
Schistosoma mansoni serine/threonine protein kinase 0.0034 0.0537 0.0869
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0011 0.0123 0.0198
Echinococcus granulosus importin 5 0.0006 0.0026 0.0041
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0011 0.0127 0.009
Echinococcus granulosus NDR protein kinase 0.0005 0.0002 0.0002
Echinococcus granulosus importin subunit beta 1 0.0032 0.0501 0.0811
Echinococcus granulosus geranylgeranyl transferase type I beta subunit 0.0011 0.0123 0.0198
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0045 0.0746 0.0779
Plasmodium falciparum phd finger protein, putative 0.001 0.0098 0.0341
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0011 0.0127 0.0915
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0032 0.0504 0.0526
Brugia malayi hypothetical protein 0.0008 0.0069 0.0142
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0027 0.0415 0.212
Plasmodium vivax SET domain protein, putative 0.001 0.0106 0.0427
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0005 0.0014 0.0022
Entamoeba histolytica hypothetical protein 0.0026 0.039 0.1983
Mycobacterium ulcerans acetyl-CoA synthetase 0.0008 0.0057 0.002
Echinococcus granulosus GPCR family 2 0.0049 0.082 0.1328
Brugia malayi nuclear hormone receptor 0.0021 0.0307 0.0633
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.1246 1
Trichomonas vaginalis CAMK family protein kinase 0.0068 0.1173 0.5992
Leishmania major farnesyltransferase beta subunit 0.0042 0.068 0.54
Brugia malayi mbt repeat family protein 0.0015 0.0186 0.0382
Brugia malayi Nuclear hormone receptor-like 1 0.0045 0.0746 0.154
Leishmania major hypothetical protein, conserved 0.0013 0.0146 0.1068
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0044 0.0726 0.1176
Trichomonas vaginalis AGC family protein kinase 0.0013 0.0151 0.0773
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0015 0.0199 0.1529
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.026 0.1997
Trypanosoma brucei hypothetical protein, conserved 0.0072 0.1246 1
Onchocerca volvulus Huntingtin homolog 0.0131 0.2316 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0057 0.002
Loa Loa (eye worm) G protein alpha subunit 3 0.0006 0.0029 0.0046
Loa Loa (eye worm) hypothetical protein 0.0014 0.017 0.0274
Echinococcus multilocularis lysosomal alpha glucosidase 0.0055 0.0933 0.0974
Loa Loa (eye worm) hypothetical protein 0.001 0.0098 0.0157
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0008 0.0057 0.002
Brugia malayi intermediate filament protein 0.003 0.0463 0.0956
Echinococcus granulosus protein kinase C gamma type 0.0005 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0026 0.0397 0.0642
Loa Loa (eye worm) hypothetical protein 0.0011 0.0123 0.0198
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0034 0.0537 0.0869
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0008 0.0057 0.0044
Mycobacterium ulcerans DNA polymerase IV 0.0027 0.0415 0.038
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.257 0.4167
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0021 0.0306 0.027
Trypanosoma brucei geranylgeranyl transferase type II beta subunit, putative 0.0011 0.0123 0.0882
Schistosoma mansoni GTP-binding protein alpha subunit 0.0006 0.0029 0.0046
Trichomonas vaginalis sucrase-isomaltase, putative 0.0012 0.0141 0.072
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0008 0.0057 0.0091
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0045 0.0746 0.154
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0015 0.0199 0.1008
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0006 0.0029 0.015
Echinococcus multilocularis muscleblind protein 0.0046 0.0761 0.0795
Brugia malayi Latrophilin receptor protein 2 0.0049 0.082 0.1693
Loa Loa (eye worm) hypothetical protein 0.002 0.0275 0.0445
Loa Loa (eye worm) heterochromatin protein 1 0.0024 0.0351 0.0569
Loa Loa (eye worm) hypothetical protein 0.0046 0.0761 0.1233
Trypanosoma brucei DNA polymerase IV, putative 0.0027 0.0415 0.3255
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0007 0.0037 0.0186
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0307 0.0497
Onchocerca volvulus 0.0031 0.0481 0.1974
Brugia malayi Nuclear hormone receptor-like 1 0.0024 0.0354 0.0731
Giardia lamblia NADH oxidase lateral transfer candidate 0.0011 0.0127 0.0536
Trichomonas vaginalis antibiotic synthetase, putative 0.0008 0.0057 0.029
Trypanosoma cruzi trypanothione reductase, putative 0.0033 0.0525 0.4165
Echinococcus granulosus Glutaredoxin protein 5 0.0009 0.0073 0.0117
Trypanosoma brucei NADPH-dependent diflavin oxidoreductase 1 0.0007 0.0037 0.0184
Echinococcus granulosus GTP binding nuclear protein Ran 0.0023 0.0346 0.0561
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0049 0.082 0.0856
Leishmania major cytochrome P450 reductase, putative 0.0006 0.0023 0.0073
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0049 0.082 0.1328
Loa Loa (eye worm) hypothetical protein 0.0008 0.0057 0.0091
Echinococcus granulosus protein arginine N methyltransferase 8 0.0005 0.0014 0.0021
Schistosoma mansoni serine/threonine protein kinase 0.0005 0.0002 0.0002
Toxoplasma gondii isocitrate dehydrogenase 0.0005 0.0014 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0088 0.0451
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0021 0.0307 0.032
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0005 0.0014 0.0021
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0111 0.1958 1
Schistosoma mansoni tar DNA-binding protein 0.0024 0.0358 0.058
Echinococcus granulosus fructose 16 bisphosphate aldolase 0.0029 0.045 0.0729
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0008 0.0069 0.0032
Trypanosoma cruzi polypeptide deformylase-like protein, putative 0.0053 0.0892 0.7132
Mycobacterium ulcerans oxidoreductase 0.0016 0.0202 0.0166
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0006 0.0029 0.003
Schistosoma mansoni serine/threonine protein kinase 0.0005 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0021 0.0307 0.0497
Onchocerca volvulus 0.0016 0.0202 0.0753
Brugia malayi nuclear hormone receptor 0.0045 0.0746 0.154
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.018 0.029
Loa Loa (eye worm) transcription factor SMAD2 0.0045 0.075 0.1215
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0307 0.0497
Toxoplasma gondii N-acetylglucosaminylphosphatidylinositol deacetylase 0.0018 0.0248 0.0965
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0021 0.0306 0.063
Schistosoma mansoni importin beta-1 0.0032 0.0501 0.0811
Schistosoma mansoni hypothetical protein 0.0106 0.1869 0.303
Echinococcus granulosus inositol monophosphatase 1 0.0042 0.0684 0.1108
Echinococcus multilocularis protein arginine N methyltransferase 8 0.0005 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0013 0.0146 0.0235
Plasmodium falciparum acyl-CoA synthetase 0.002 0.0275 0.1061
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0684 0.5438
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0017 0.0223 0.0232
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0012 0.0141 0.071
Toxoplasma gondii histone lysine methyltransferase SET1 0.0025 0.0377 0.1486
Entamoeba histolytica protein kinase, putative 0.0034 0.0537 0.2732
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0034 0.0537 0.056
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0011 0.0127 0.0132
Loa Loa (eye worm) hypothetical protein 0.0131 0.2316 0.3754
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0005 0.0014 0.0071
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.001 0.0102 0.0106
Trichomonas vaginalis alpha-glucosidase, putative 0.0012 0.0141 0.072
Trypanosoma brucei hypothetical protein, conserved 0.0015 0.0199 0.1504
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0006 0.0029 0.0046
Echinococcus granulosus chromobox protein 1 0.0024 0.0351 0.0569
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0021 0.0307 0.032
Brugia malayi nuclear receptor NHR-67 0.0021 0.0307 0.0633
Entamoeba histolytica N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase, putative 0.0018 0.0248 0.1257
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0032 0.0513 0.083
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0045 0.0746 0.154
Loa Loa (eye worm) hypothetical protein 0.0005 0.0002 0.0002
Brugia malayi PHD-finger family protein 0.001 0.0098 0.0201
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0008 0.0071 0.0244
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0029 0.045 0.356
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0415 0.3255
Trichomonas vaginalis alpha-glucosidase, putative 0.0012 0.0141 0.072
Loa Loa (eye worm) hypothetical protein 0.0016 0.0202 0.0326
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0008 0.0057 0.002
Schistosoma mansoni hypothetical protein 0.0192 0.3443 0.5582
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0102 0.0209
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0006 0.0029 0.0046
Onchocerca volvulus 0.0008 0.0057 0.012
Schistosoma mansoni fructose 16-bisphosphate aldolase 0.0029 0.045 0.0729
Onchocerca volvulus 0.0032 0.0504 0.2074
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0008 0.0057 0.0116
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0109 0.1913 0.1883
Giardia lamblia Sgs1 DNA helicase, putative 0.001 0.0102 0.0407
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0157 0.1183
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0006 0.0032 0.005
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0014 0.0178 0.0651
Entamoeba histolytica glucosamine-6-phosphate isomerase, putative 0.0018 0.0248 0.1257
Mycobacterium ulcerans aldehyde dehydrogenase 0.0032 0.0504 0.0469
Entamoeba histolytica hypothetical protein 0.0048 0.0796 0.4055
Chlamydia trachomatis protoporphyrinogen oxidase 0.0072 0.1235 0.4836
Echinococcus multilocularis survival motor neuron protein 1 0.0268 0.4838 0.5055
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0008 0.0057 0.002
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0076 0.1306 0.1339
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0014 0.0177 0.0287
Loa Loa (eye worm) hypothetical protein 0.0014 0.017 0.0274
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0006 0.0029 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0088 0.0451
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0397 0.0819
Schistosoma mansoni lamin 0.003 0.0463 0.075
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0048 0.0803 0.4098
Brugia malayi hypothetical protein 0.0021 0.0307 0.0633
Schistosoma mansoni geranylgeranyl transferase type II beta subunit 0.0011 0.0123 0.0198
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.0006 0.0026 0.0098
Plasmodium vivax flavodoxin domain containing protein 0.0006 0.0023 0.009
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0044 0.0726 0.3706
Entamoeba histolytica Ran family GTPase 0.0023 0.0346 0.1759
Loa Loa (eye worm) hypothetical protein 0.0051 0.0859 0.1392
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0007 0.0043 0.0237
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0006 0.0029 0.015
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0049 0.082 0.0856
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0045 0.0746 0.1208
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0008 0.0057 0.0091
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0048 0.0803 0.3242
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0005 0.0014 0.0014
Echinococcus multilocularis serine threonine protein kinase 0.0005 0.0002 0.0002
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0008 0.0069 0.0478
Echinococcus multilocularis serine:threonine protein kinase N2 0.0005 0.0002 0.0002
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0102 0.0209
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0005 0.0011 0.0057
Loa Loa (eye worm) fructose-bisphosphate aldolase 1 0.0029 0.045 0.0729
Loa Loa (eye worm) ATP-dependent DNA helicase 0.001 0.0102 0.0164
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0026 0.0397 0.0397
Trypanosoma cruzi NADPH-dependent FMN/FAD containing oxidoreductase, putative 0.0007 0.0037 0.0213
Brugia malayi Isocitrate dehydrogenase 0.0005 0.0014 0.0027
Trypanosoma brucei polo-like protein kinase 0.0068 0.1173 0.9407
Trypanosoma brucei Peptide deformylase 2 0.0053 0.0892 0.7124
Plasmodium vivax NADPH-cytochrome p450 reductase, putative 0.0007 0.0037 0.0146
Onchocerca volvulus 0.0051 0.0859 0.3628
Entamoeba histolytica protein kinase , putative 0.0034 0.0537 0.2732
Trypanosoma cruzi DNA polymerase kappa, putative 0.0027 0.0415 0.3275
Trichomonas vaginalis ap endonuclease, putative 0.0007 0.0043 0.0221
Leishmania major acetyl-CoA synthetase, putative 0.0008 0.0057 0.0347
Giardia lamblia Kinase, PLK 0.0068 0.1173 0.5944
Giardia lamblia Fructose-bisphosphate aldolase 0.0111 0.1958 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.002 0.0275 0.0239
Loa Loa (eye worm) hypothetical protein 0.0005 0.001 0.0016
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0021 0.0306 0.2366
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0029 0.045 0.356
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0042 0.0684 0.3494
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0006 0.0019 0.0029
Echinococcus granulosus Nuclear hormone receptor HR96 0.0021 0.0307 0.0497
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0057 0.002
Loa Loa (eye worm) inositol-1 0.0042 0.0684 0.1108
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0054 0.0913 0.0932
Schistosoma mansoni coup transcription factor 0.0045 0.0746 0.1208
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0011 0.0127 0.0218
Brugia malayi Pre-SET motif family protein 0.001 0.0106 0.0218
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0007 0.0043 0.0173
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0525 0.957 1
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0023 0.0346 0.1363
Loa Loa (eye worm) hypothetical protein 0.0006 0.0029 0.0046
Schistosoma mansoni hypothetical protein 0.0192 0.3443 0.5582
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0011 0.0127 0.0941
Brugia malayi hypothetical protein 0.0048 0.0796 0.1643
Plasmodium falciparum protoporphyrinogen oxidase 0.0016 0.0202 0.0763
Entamoeba histolytica hypothetical protein 0.0048 0.0796 0.4055
Loa Loa (eye worm) hypothetical protein 0.0016 0.0202 0.0326
Echinococcus granulosus fructose bisphosphate aldolase class I 0.0029 0.045 0.0729
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0144 0.257 0.5312
Plasmodium falciparum peptide deformylase 0.0139 0.2475 1
Loa Loa (eye worm) hypothetical protein 0.0268 0.4838 0.7845
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0011 0.0127 0.051
Plasmodium vivax hypothetical protein, conserved 0.0016 0.0202 0.0813
Echinococcus granulosus thioredoxin glutathione reductase 0.0034 0.0533 0.0864
Trichomonas vaginalis AGC family protein kinase 0.0013 0.0151 0.0773
Loa Loa (eye worm) jmjC domain-containing protein 0.0013 0.0148 0.0238
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0042 0.0684 0.2636
Loa Loa (eye worm) importin-beta domain-containing protein 0.0006 0.0026 0.0041
Echinococcus multilocularis geranylgeranyl transferase type I beta subunit 0.0011 0.0123 0.0127
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0144 0.257 0.4167
Echinococcus multilocularis transportin 1 0.0006 0.0026 0.0027
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0045 0.0746 0.1208
Loa Loa (eye worm) hypothetical protein 0.0006 0.0029 0.0046
Entamoeba histolytica arginine N-methyltransferase protein, putative 0.0008 0.0069 0.0344
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0032 0.0504 0.0816
Plasmodium falciparum nitric oxide synthase, putative 0.0007 0.0037 0.0092
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0005 0.0002 0.0002
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0034 0.0537 0.2732
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0005 0.0002 0.0002
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0397 0.0819
Loa Loa (eye worm) hypothetical protein 0.0021 0.0307 0.0497
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0007 0.0043 0.0007
Brugia malayi Muscleblind-like protein 0.0046 0.0761 0.1572
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0397 0.0342
Echinococcus granulosus N acetylglucosaminyl phosphatidylinositol 0.0018 0.0248 0.0401
Loa Loa (eye worm) hypothetical protein 0.0021 0.0307 0.0497
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0016 0.0202 0.021
Schistosoma mansoni alpha glucosidase 0.0012 0.0141 0.0228
Echinococcus granulosus histone acetyltransferase MYST2 0.0017 0.0223 0.036
Plasmodium vivax hypothetical protein, conserved 0.0016 0.0202 0.0813
Loa Loa (eye worm) MBCTL1 0.0017 0.0223 0.036
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0011 0.0123 0.0456
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0008 0.0057 0.002
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0123 0.0908
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.0397 0.0397
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.001 0.0106 0.0171
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0397 0.0342
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0007 0.0043 0.0105
Brugia malayi hypothetical protein 0.0024 0.0354 0.0731
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0029 0.0442 0.2255
Echinococcus multilocularis dna polymerase kappa 0.0027 0.0415 0.0433
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0141 0.1057
Plasmodium falciparum glutathione reductase 0.0033 0.0525 0.2078
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0055 0.0933 0.1511
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0029 0.045 0.356
Loa Loa (eye worm) TAR-binding protein 0.0024 0.0358 0.058
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0009 0.0074 0.0038
Trypanosoma cruzi UDP-galactopyranose mutase 0.0016 0.0202 0.1547
Schistosoma mansoni atypical protein kinase C 0.0005 0.0002 0.0002
Plasmodium falciparum transportin 0.0006 0.0026 0.005
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0016 0.0214 0.0826
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0011 0.0123 0.0626
Schistosoma mansoni DNA polymerase eta 0.0046 0.0753 0.1219
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0011 0.0127 0.0941
Entamoeba histolytica hypothetical protein 0.0048 0.0796 0.4055
Echinococcus granulosus nervana 2 0.0008 0.0064 0.0103
Loa Loa (eye worm) hypothetical protein 0.0007 0.0037 0.0058
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0021 0.0306 0.0494
Treponema pallidum fructose-bisphosphate aldolase 0.0111 0.1958 0.7905
Trypanosoma brucei N-acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase 0.0018 0.0248 0.19
Plasmodium falciparum DNA repair protein REV1, putative 0.0008 0.0071 0.023
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0042 0.068 0.2715
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0217 0.0839
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase 0.0029 0.045 0.047
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0007 0.0043 0.0266
Loa Loa (eye worm) hypothetical protein 0.0131 0.2316 0.3754
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0501 0.3951
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0068 0.1173 0.1902
Toxoplasma gondii histone lysine-specific demethylase 0.0016 0.0202 0.0776
Trichomonas vaginalis chromobox protein, putative 0.0024 0.0351 0.1794
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0032 0.0165
Loa Loa (eye worm) hypothetical protein 0.0024 0.0354 0.0573
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0048 0.0803 0.3215
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0023 0.0346 0.1671
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0012 0.0141 0.0228
Onchocerca volvulus Protein ultraspiracle homolog 0.0045 0.0746 0.3134
Entamoeba histolytica protein kinase domain containing protein 0.0034 0.0537 0.2732
Echinococcus multilocularis protein arginine methyltransferase 0.0005 0.0014 0.0014
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0415 0.3255
Schistosoma mansoni serine/threonine protein kinase 0.0005 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0021 0.0307 0.0497
Plasmodium falciparum serine/threonine protein kinase, putative 0.0034 0.0537 0.2124
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0415 0.3255
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0045 0.0746 0.1208
Mycobacterium tuberculosis Conserved hypothetical protein 0.0018 0.0248 0.0243
Echinococcus multilocularis inositol monophosphatase 1 0.0042 0.0684 0.0714
Toxoplasma gondii isocitrate dehydrogenase 0.0005 0.0014 0.0015
Trypanosoma brucei DNA polymerase IV, putative 0.0027 0.0415 0.3255
Entamoeba histolytica PH domain containing protein kinase, putative 0.0009 0.0075 0.0373
Brugia malayi Nuclear hormone receptor E75 0.0021 0.0307 0.0633
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0009 0.0075 0.0249
Toxoplasma gondii AGC kinase 0.0013 0.0151 0.0572
Loa Loa (eye worm) hypothetical protein 0.0016 0.0202 0.0326
Loa Loa (eye worm) hypothetical protein 0.003 0.0463 0.075
Trypanosoma cruzi polypeptide deformylase-like protein, putative 0.0053 0.0892 0.7132
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0006 0.0029 0.0046
Toxoplasma gondii thioredoxin reductase 0.0033 0.0525 0.2089
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0007 0.0043 0.0069
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0256 0.025
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0011 0.0123 0.0626
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0007 0.0043 0.0069
Trypanosoma cruzi DNA polymerase kappa, putative 0.0027 0.0415 0.3275
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0007 0.0043 0.0238
Leishmania major polypeptide deformylase-like protein, putative 0.0053 0.0892 0.7124
Trypanosoma cruzi PAB1-binding protein , putative 0.0013 0.0146 0.1093
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.002 0.0275 0.0836
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0006 0.0029 0.0059
Plasmodium vivax farnesyltransferase beta subunit, putative 0.0042 0.068 0.2744
Brugia malayi fructose-bisphosphate aldolase 1 0.0029 0.045 0.093
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0045 0.0746 0.154
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0012 0.0141 0.072
Brugia malayi Bloom's syndrome protein homolog 0.0025 0.0367 0.0757
Toxoplasma gondii aldehyde dehydrogenase 0.0032 0.0504 0.2003
Echinococcus granulosus polycomb protein SCMH1 0.0015 0.0186 0.03
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0164 0.2933 0.3064
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0023 0.0344 0.0342
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0005 0.0002 0.0002
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0007 0.0037 0.0213
Schistosoma mansoni nuclear hormone receptor 0.0045 0.0746 0.1208
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0006 0.0029 0.015
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0501 0.3951
Loa Loa (eye worm) hypothetical protein 0.0045 0.0746 0.1208
Loa Loa (eye worm) hypothetical protein 0.0093 0.1623 0.263
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0009 0.0075 0.0302
Mycobacterium ulcerans aldehyde dehydrogenase 0.0032 0.0504 0.0469
Giardia lamblia Histone acetyltransferase GCN5 0.0044 0.0729 0.3647
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0008 0.0071 0.0144
Schistosoma mansoni ap endonuclease 0.0007 0.0043 0.0069
Brugia malayi Protein kinase domain containing protein 0.0005 0.0002 0.0003
Plasmodium vivax geranylgeranyltransferase, putative 0.0011 0.0123 0.0494
Giardia lamblia Kinase, AGC PKA 0.0009 0.0075 0.0271
Brugia malayi ImpB/MucB/SamB family protein 0.0027 0.0415 0.0857
Echinococcus multilocularis thioredoxin glutathione reductase 0.0034 0.0533 0.0557
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0045 0.0746 0.1208
Echinococcus multilocularis nuclear receptor nhr 48 0.0021 0.0307 0.032
Entamoeba histolytica protein kinase, putative 0.0013 0.0151 0.0762
Echinococcus granulosus protein kinase c epsilon type 0.0005 0.0002 0.0002
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0042 0.068 0.347
Loa Loa (eye worm) oxidoreductase 0.0008 0.0057 0.0091
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0068 0.1173 0.1902
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0011 0.0127 0.0915
Loa Loa (eye worm) AGC/PKN protein kinase 0.0005 0.0002 0.0002
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0084 0.1462 0.15
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0164 0.2933 0.4755
Plasmodium vivax geranylgeranyl transferase type2 beta subunit, putative 0.0011 0.0123 0.0494
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0011 0.0127 0.0204
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0009 0.0074 0.0128
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0032 0.0165
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0033 0.0525 0.053
Onchocerca volvulus 0.0014 0.0177 0.0648
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0021 0.0307 0.1215
Schistosoma mansoni nuclear receptor 0.0021 0.0307 0.0497
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.0312 0.1211
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0011 0.0127 0.0343
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0015 0.0199 0.0754
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0006 0.0029 0.0046
Trichomonas vaginalis set domain proteins, putative 0.0081 0.1399 0.7141
Schistosoma mansoni GTP-binding protein alpha subunit 0.0006 0.0029 0.0046
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0027 0.0415 0.0416
Echinococcus granulosus Nuclear hormone receptor HR96 0.0021 0.0307 0.0497
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0006 0.0029 0.0046
Loa Loa (eye worm) follicle stimulating hormone receptor 0.016 0.2866 0.4647
Trichomonas vaginalis CAMK family protein kinase 0.0068 0.1173 0.5992
Loa Loa (eye worm) latrophilin receptor protein 2 0.0049 0.082 0.1328
Brugia malayi isocitrate dehydrogenase 0.0005 0.0014 0.0027
Giardia lamblia Aurora kinase 0.0034 0.0537 0.2654
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0009 0.0075 0.0121
Loa Loa (eye worm) thioredoxin reductase 0.0033 0.0525 0.0851
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0006 0.0029 0.0046
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0415 0.3255
Trypanosoma cruzi DNA polymerase kappa, putative 0.0027 0.0415 0.3275
Entamoeba histolytica hypothetical protein 0.0008 0.0069 0.0344
Echinococcus multilocularis expressed protein 0.0006 0.0029 0.003
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0005 0.0014 0.0071
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0011 0.0127 0.0117
Echinococcus multilocularis protein kinase c epsilon type 0.0005 0.0002 0.0002
Echinococcus multilocularis lysine specific demethylase 5A 0.0012 0.0136 0.0142
Echinococcus multilocularis fructose bisphosphate aldolase class I 0.0029 0.045 0.047
Loa Loa (eye worm) hypothetical protein 0.0021 0.0307 0.0497
Echinococcus multilocularis PHD finger protein rhinoceros 0.001 0.0098 0.0101
Plasmodium vivax thioredoxin reductase, putative 0.0033 0.0525 0.2121
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0256 0.025
Entamoeba histolytica protein kinase, putative 0.0034 0.0537 0.2732
Loa Loa (eye worm) hypothetical protein 0.0006 0.0029 0.0046
Echinococcus multilocularis importin subunit beta 1 0.0032 0.0501 0.0523
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0111 0.1958 1
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0044 0.0726 0.2892
Trypanosoma brucei NADPH-cytochrome p450 reductase, putative 0.0007 0.0037 0.0184
Loa Loa (eye worm) kap beta 3 protein 0.0006 0.0026 0.0041
Toxoplasma gondii propionate-CoA ligase 0.0008 0.0057 0.0188
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0006 0.0029 0.0059
Giardia lamblia Rab geranylgeranyltransferase 0.0011 0.0123 0.0515
Brugia malayi jmjC domain containing protein 0.0013 0.0148 0.0304
Leishmania major DNA polymerase eta, putative 0.0027 0.0408 0.3197
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0049 0.082 0.1693
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.001 0.0102 0.0357
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.001 0.0102 0.0106
Brugia malayi AMP-binding enzyme family protein 0.0008 0.0057 0.0116
Plasmodium vivax glutathione reductase, putative 0.0033 0.0525 0.2121
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0015 0.0199 0.1504
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0023 0.0346 0.2697
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0045 0.0746 0.0779
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0008 0.0069 0.0032
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0042 0.068 0.1101
Giardia lamblia DINP protein human, muc B family 0.0027 0.0415 0.2027
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0057 0.002
Echinococcus multilocularis chromobox protein 1 0.0024 0.0351 0.0366
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0005 0.0002 0.0002
Plasmodium vivax peptide deformylase, putative 0.0139 0.2475 1
Schistosoma mansoni tar DNA-binding protein 0.0024 0.0358 0.058
Schistosoma mansoni importin-beta 2 0.0006 0.0026 0.0041
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0016 0.0202 0.0763
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0008 0.0057 0.0347
Schistosoma mansoni serine/threonine protein kinase 0.0005 0.0002 0.0002
Brugia malayi acetyltransferase, GNAT family protein 0.0164 0.2933 0.6061
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0032 0.0165
Entamoeba histolytica protein kinase, putative 0.0013 0.0151 0.0762
Schistosoma mansoni RAR-like nuclear receptor 0.0045 0.0746 0.1208
Brugia malayi Nuclear hormone receptor-like 1 0.0024 0.0354 0.0731
Echinococcus multilocularis cpg binding protein 0.0012 0.0128 0.0133
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.0209 0.043
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0045 0.0746 0.1208
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0008 0.0057 0.0091
Brugia malayi conserved hypotetical protein 0.0021 0.0307 0.0633
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0015 0.0199 0.0322
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0008 0.0071 0.0144
Trypanosoma brucei Polypeptide deformylase 1 0.0053 0.0892 0.7124
Echinococcus granulosus lamin dm0 0.003 0.0463 0.075
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0011 0.0127 0.0941
Trichomonas vaginalis antibiotic synthetase, putative 0.0008 0.0057 0.029
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.0042 0.068 0.347
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0012 0.0141 0.072
Echinococcus granulosus expressed protein 0.0006 0.0029 0.0046
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0055 0.0919 0.1899
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0307 0.0497
Mycobacterium tuberculosis Probable protoporphyrinogen oxidase HemY (protoporphyrinogen-IX oxidase) (protoporphyrinogenase) (PPO) 0.0056 0.0949 0.0969
Trypanosoma cruzi Peptide deformylase 2, putative 0.0053 0.0892 0.7132
Echinococcus granulosus serine/threonine protein kinase 0.0009 0.0075 0.0121
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0015 0.0199 0.0208
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0021 0.0306 0.0302
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0007 0.0043 0.0119
Loa Loa (eye worm) hypothetical protein 0.0006 0.0029 0.0046
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0008 0.0057 0.0188
Echinococcus granulosus lysosomal alpha glucosidase 0.0055 0.0933 0.1511
Brugia malayi AMP-binding enzyme family protein 0.0008 0.0057 0.0116
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0011 0.0127 0.0204
Onchocerca volvulus 0.0055 0.0919 0.3893
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0005 0.0014 0.0029
Echinococcus granulosus protoporphyrinogen oxidase 0.0056 0.0949 0.1538
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0102 0.0371
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0006 0.0029 0.0046
Schistosoma mansoni cpg binding protein 0.0012 0.0128 0.0206
Toxoplasma gondii LsmAD domain-containing protein 0.0013 0.0146 0.0548
Echinococcus granulosus neutral alpha glucosidase AB 0.0012 0.0141 0.0228
Loa Loa (eye worm) hypothetical protein 0.0021 0.0307 0.0497
Loa Loa (eye worm) hypothetical protein 0.0045 0.0746 0.1208
Loa Loa (eye worm) hypothetical protein 0.002 0.0275 0.0445
Loa Loa (eye worm) nuclear receptor NHR-67 0.0021 0.0307 0.0497
Schistosoma mansoni serine/threonine-protein kinase 0.0009 0.0083 0.0134
Loa Loa (eye worm) FAD binding domain-containing protein 0.0007 0.0037 0.0058
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0015 0.0199 0.1529
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0071 0.1219 0.1976
Brugia malayi FAD binding domain containing protein 0.0007 0.0037 0.0074
Schistosoma mansoni retinoic acid receptor RXR 0.0045 0.0746 0.1208
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0008 0.0057 0.0375
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0011 0.0127 0.0915
Trichomonas vaginalis glutathione reductase, putative 0.0011 0.0127 0.0647
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0042 0.068 0.1403
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0026 0.0397 0.0362
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0076 0.1306 0.1339
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0024 0.0354 0.0573
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0005 0.0002 0.0002
Echinococcus multilocularis citrate lyase subunit beta protein 0.0008 0.0069 0.0071
Echinococcus granulosus L aminoadipate semialdehyde 0.0031 0.0481 0.0779
Loa Loa (eye worm) jmjC domain-containing protein 0.002 0.0292 0.0472
Brugia malayi TAR-binding protein 0.0024 0.0358 0.0739
Schistosoma mansoni amine oxidase 0.0016 0.0202 0.0326
Echinococcus multilocularis snurportin 1 0.034 0.6167 0.6444
Trypanosoma cruzi Peptide deformylase 2, putative 0.0053 0.0892 0.7132
Toxoplasma gondii histone arginine methyltransferase PRMT1 0.0005 0.0014 0.0014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0045 0.0746 0.1208
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0044 0.0726 0.3706
Echinococcus granulosus lysine specific histone demethylase 1A 0.0016 0.0202 0.0326
Schistosoma mansoni hypothetical protein 0.0049 0.082 0.1328
Loa Loa (eye worm) AGC/AKT protein kinase 0.0013 0.0151 0.0244
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0024 0.0348 0.0563
Schistosoma mansoni transcription factor LCR-F1 0.0048 0.0796 0.1289
Leishmania major hypothetical protein, conserved 0.0072 0.1246 1
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0015 0.0199 0.1504
Trypanosoma brucei Protein arginine N-methyltransferase 1 catalytic subunit 0.0008 0.0069 0.045
Schistosoma mansoni jumonji/arid domain-containing protein 0.0013 0.0148 0.0238
Echinococcus multilocularis aurora kinase A 0.0034 0.0537 0.056
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0045 0.0746 0.1208
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0006 0.0029 0.0046
Echinococcus multilocularis serine:threonine protein kinase N2 0.0005 0.0002 0.0002
Loa Loa (eye worm) MH2 domain-containing protein 0.0045 0.075 0.1215
Loa Loa (eye worm) RecQ helicase 0.0025 0.0367 0.0594
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0006 0.0029 0.003
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.001 0.0095 0.0153
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0015 0.0199 0.1018
Mycobacterium tuberculosis Conserved hypothetical protein 0.0016 0.0202 0.0194
Mycobacterium ulcerans hypothetical protein 0.0008 0.0069 0.0032
Brugia malayi RNA binding protein 0.0024 0.0358 0.0739
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0024 0.0354 0.0573
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0008 0.0064 0.0103
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0005 0.0014 0.0054
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0015 0.0199 0.0411
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0397 0.2017
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0027 0.0415 0.3256
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0024 0.0354 0.0573
Trichomonas vaginalis chromobox protein, putative 0.0024 0.0351 0.1794
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0006 0.0032 0.0165
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0415 0.3255
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0042 0.0684 0.065
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0109 0.1913 0.1883
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0042 0.0684 0.3486
Trichomonas vaginalis NADPH fad oxidoreductase, putative 0.0006 0.0023 0.0117
Entamoeba histolytica PH domain containing protein kinase, putative 0.0009 0.0075 0.0373
Loa Loa (eye worm) hypothetical protein 0.0106 0.1869 0.303
Echinococcus multilocularis neutral alpha glucosidase AB 0.0012 0.0141 0.0147
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0397 0.0362
Leishmania major trypanothione reductase 0.0033 0.0525 0.4148
Trichomonas vaginalis maltase-glucoamylase, putative 0.0012 0.0141 0.072
Brugia malayi ImpB/MucB/SamB family protein 0.0046 0.0753 0.1555
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0084 0.1462 0.1413
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0007 0.0043 0.021
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0011 0.0127 0.0914
Schistosoma mansoni hypothetical protein 0.0049 0.082 0.1328
Brugia malayi orphan nuclear receptor NR2E1 0.0021 0.0307 0.0633
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0015 0.0199 0.1504
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0005 0.0002 0.0002
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0006 0.0029 0.0059
Trichomonas vaginalis ap endonuclease, putative 0.0007 0.0043 0.0221
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0029 0.045 0.356
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.0275 0.0271
Brugia malayi AMP-binding enzyme family protein 0.0008 0.0057 0.0116
Trypanosoma cruzi DNA damage repair protein, putative 0.0008 0.0071 0.0486
Loa Loa (eye worm) hypothetical protein 0.0024 0.0354 0.0573
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0072 0.1235 0.1203
Treponema pallidum polypeptide deformylase (def) 0.0139 0.2475 1
Schistosoma mansoni DNA polymerase IV / kappa 0.0008 0.0071 0.0113
Brugia malayi Probable protein farnesyltransferase beta subunit, putative 0.0011 0.0123 0.0252
Entamoeba histolytica protein kinase 2, putative 0.0009 0.0075 0.0373
Brugia malayi hypothetical protein 0.0268 0.4838 1
Trichomonas vaginalis AGC family protein kinase 0.0013 0.0151 0.0773
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0012 0.0141 0.071
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0111 0.1958 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0684 0.5452
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0034 0.0537 0.2732
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0011 0.0127 0.0472
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0005 0.0014 0.0022
Toxoplasma gondii fructose-1,6-bisphosphate aldolase 0.0029 0.045 0.1786
Loa Loa (eye worm) hypothetical protein 0.002 0.0275 0.0445
Onchocerca volvulus Bile acid receptor homolog 0.0045 0.0746 0.3134
Schistosoma mansoni DNA helicase recq5 0.001 0.0102 0.0164
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0016 0.0202 0.0813
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0045 0.0746 0.0779
Onchocerca volvulus 0.0021 0.0307 0.1215
Echinococcus granulosus lamin 0.003 0.0463 0.075
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0011 0.0127 0.0914
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.0042 0.068 0.3462
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0006 0.0029 0.003
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0011 0.0123 0.0626
Schistosoma mansoni hypothetical protein 0.0049 0.082 0.1328
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0016 0.0202 0.0763
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0008 0.0057 0.0044
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.257 0.4167
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0006 0.0029 0.0046
Brugia malayi Protein kinase domain containing protein 0.0005 0.0002 0.0003
Echinococcus granulosus ATP dependent DNA helicase Q5 0.001 0.0102 0.0164
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0123 0.0908
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0008 0.0057 0.0044
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0045 0.0746 0.1208
Schistosoma mansoni survival motor neuron protein 0.0055 0.0919 0.149
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0007 0.0037 0.0213
Leishmania major hypothetical protein, conserved 0.0006 0.0026 0.0099
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0021 0.0306 0.0318
Trichomonas vaginalis DNA helicase recq1, putative 0.0025 0.0367 0.1873
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.0042 0.068 0.0709
Loa Loa (eye worm) PHD-finger family protein 0.001 0.0098 0.0157
Loa Loa (eye worm) hypothetical protein 0.0008 0.0057 0.0091
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.0209 0.0337
Loa Loa (eye worm) mbt repeat family protein 0.0015 0.0186 0.03
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.001 0.0106 0.011
Leishmania major geranylgeranyltransferase, putative 0.0011 0.0123 0.0882
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0011 0.0123 0.0252
Trypanosoma brucei chrX additional, unordered contigs 0.0008 0.0071 0.0458
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0017 0.0223 0.036
Leishmania major lanosterol synthase, putative 0.0012 0.0137 0.0999
Leishmania major DNA damage repair protein, putative 0.0008 0.0071 0.0459
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0007 0.0043 0.0044
Echinococcus multilocularis SAM and MBT domain containing protein 0.0015 0.0186 0.0193
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0006 0.0029 0.015
Trypanosoma cruzi hypothetical protein, conserved 0.0008 0.0071 0.0486
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0006 0.0029 0.0059
Schistosoma mansoni serine/threonine protein kinase 0.0068 0.1173 0.1902
Trypanosoma cruzi lanosterol synthase, putative 0.0023 0.0344 0.2702
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.0463 0.0956
Trypanosoma brucei hypothetical protein, conserved 0.0008 0.0071 0.0458
Brugia malayi glutathione reductase 0.0033 0.0525 0.1084
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0008 0.0069 0.0472
Leishmania major p450 reductase, putative 0.0007 0.0037 0.0185
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0034 0.0537 0.2732
Trichomonas vaginalis ran, putative 0.0023 0.0346 0.1769
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0155 0.2773 0.4496
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0006 0.0029 0.0046
Brugia malayi kap beta 3 protein 0.0006 0.0026 0.0052
Giardia lamblia Rab geranylgeranyltransferase 0.0044 0.0726 0.3631
Loa Loa (eye worm) hypothetical protein 0.0045 0.0746 0.1208
Echinococcus multilocularis isocitrate dehydrogenase 0.0005 0.0014 0.0014
Echinococcus multilocularis dna polymerase eta 0.0046 0.0753 0.0786
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.001 0.0106 0.0389
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0006 0.0029 0.015
Loa Loa (eye worm) intermediate filament protein 0.003 0.0463 0.075
Mycobacterium tuberculosis Probable dehydrogenase 0.0076 0.1306 0.1339
Schistosoma mansoni inositol monophosphatase 0.0042 0.0684 0.1108
Trypanosoma cruzi lanosterol synthase, putative 0.0023 0.0344 0.2702
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0346 0.2718
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0005 0.0014 0.0021
Brugia malayi hypothetical protein 0.0016 0.0202 0.0415
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0256 0.025
Schistosoma mansoni aldehyde dehydrogenase 0.0032 0.0504 0.0816
Brugia malayi Pre-SET motif family protein 0.0071 0.1219 0.2519
Schistosoma mansoni tar DNA-binding protein 0.0024 0.0358 0.058
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0015 0.0186 0.0683
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0045 0.0746 0.0779
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0057 0.002
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0044 0.0726 0.1176
Plasmodium falciparum histone acetyltransferase GCN5 0.0044 0.0729 0.2905
Trypanosoma brucei unspecified product 0.0027 0.0415 0.3255
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0032 0.0165
Echinococcus multilocularis tar DNA binding protein 0.0024 0.0358 0.0374
Plasmodium vivax N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.0018 0.0248 0.1001
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0021 0.0307 0.1215
Trichomonas vaginalis inositol monophosphatase, putative 0.0042 0.0684 0.3494
Plasmodium vivax hypothetical protein, conserved 0.001 0.0098 0.0393
Toxoplasma gondii HEAT repeat-containing protein 0.0006 0.0026 0.0064
Echinococcus granulosus nuclear receptor nhr 48 0.0021 0.0307 0.0497
Schistosoma mansoni hypothetical protein 0.0006 0.0019 0.0029
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0272 0.044
Leishmania major acetyl-CoA synthetase, putative 0.0008 0.0057 0.0347
Echinococcus multilocularis geminin 0.0192 0.3443 0.3597
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0008 0.0057 0.0044
Plasmodium falciparum N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.0018 0.0248 0.0952
Echinococcus granulosus aurora kinase A 0.0034 0.0537 0.0869
Loa Loa (eye worm) hypothetical protein 0.0021 0.0307 0.0497
Echinococcus granulosus histone lysine methyltransferase setb 0.001 0.0106 0.0171
Brugia malayi hypothetical protein 0.0051 0.0859 0.1774
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0044 0.0726 0.3706
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0008 0.0069 0.0478
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.001 0.0098 0.0157
Trypanosoma brucei DNA damage repair protein, putative 0.0008 0.0071 0.0458
Entamoeba histolytica acyl-coA synthetase, putative 0.0026 0.0397 0.2017
Loa Loa (eye worm) hypothetical protein 0.0045 0.0746 0.1208
Onchocerca volvulus 0.0009 0.0083 0.0234
Giardia lamblia DNA damage repair protein 0.0008 0.0071 0.0246
Brugia malayi chromobox protein homolog 3 0.0013 0.016 0.0329
Trichomonas vaginalis AGC family protein kinase 0.0013 0.0151 0.0773
Brugia malayi hypothetical protein 0.0008 0.0064 0.0131
Toxoplasma gondii HEAT repeat-containing protein 0.0006 0.0026 0.0064
Onchocerca volvulus 0.0015 0.0199 0.0743
Trichomonas vaginalis bromodomain-containing protein, putative 0.0048 0.0803 0.4098
Toxoplasma gondii fructose-1,6-bisphosphate aldolase 0.0029 0.045 0.1786
Echinococcus granulosus dna polymerase eta 0.0046 0.0753 0.1219
Mycobacterium ulcerans hypothetical protein 0.0008 0.0071 0.0034
Brugia malayi RNA, U transporter 1 0.0091 0.1581 0.3266
Brugia malayi nuclear receptor NHR-88 0.0045 0.0746 0.154
Trypanosoma cruzi trypanothione reductase, putative 0.0011 0.0127 0.0941
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0008 0.0057 0.0044
Mycobacterium leprae N-Acetyl-1-D-myo-Inosityl-2-Amino-2-Deoxy-alpha-D-Glucopyranoside Deacetylase MshB (GlcNAc-Ins deacetylase) 0.0018 0.0248 0.0192
Loa Loa (eye worm) hypothetical protein 0.0024 0.0354 0.0573
Brugia malayi ecdysteroid receptor 0.0045 0.0746 0.154
Onchocerca volvulus 0.0008 0.0057 0.012
Mycobacterium ulcerans hypothetical protein 0.0008 0.0069 0.0032
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0048 0.0796 0.0831
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0006 0.0029 0.0059
Echinococcus granulosus dna polymerase kappa 0.0027 0.0415 0.0672
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0031 0.0481 0.0779
Plasmodium falciparum ataxin-2 like protein, putative 0.0013 0.0146 0.0535
Onchocerca volvulus 0.003 0.0463 0.1897
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0144 0.257 0.4167
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0023 0.0346 0.0361
Schistosoma mansoni DNA helicase recq1 0.001 0.0102 0.0164
Onchocerca volvulus 0.0008 0.0057 0.012
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0076 0.1306 0.1339
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0027 0.0415 0.0672
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0045 0.0746 0.1208
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0144 0.257 0.4167
Echinococcus granulosus PHD finger protein rhinoceros 0.001 0.0098 0.0157
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.0005 0.0014 0.0071
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0009 0.0074 0.026
Trichomonas vaginalis alpha-glucosidase, putative 0.0012 0.0141 0.072
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0005 0.0014 0.0014
Trypanosoma brucei hypothetical protein, conserved 0.0008 0.0071 0.0458
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0015 0.0199 0.0322
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0042 0.068 0.347
Loa Loa (eye worm) hypothetical protein 0.001 0.0102 0.0164
Trichomonas vaginalis conserved hypothetical protein 0.0005 0.0011 0.0057
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0009 0.0075 0.0525
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0045 0.0746 0.154
Echinococcus multilocularis jumonji domain containing protein 0.0014 0.0169 0.0176
Onchocerca volvulus 0.0015 0.0186 0.0683
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0037 0.0604 0.0611
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0057 0.002
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0045 0.0746 0.154
Echinococcus granulosus fructose 16 bisphosphate aldolase 0.0029 0.045 0.0729
Echinococcus granulosus intermediate filament protein 0.003 0.0463 0.075
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0007 0.0043 0.003
Echinococcus granulosus jumonji domain containing protein 0.0014 0.0169 0.0273
Schistosoma mansoni zinc finger protein 0.0021 0.0307 0.0497
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0008 0.0057 0.0044
Toxoplasma gondii NADPH-glutathione reductase 0.0011 0.0127 0.0472
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.0501 0.1991
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0005 0.0008 0.004
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.039 0.1992
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.016 0.0816
Trypanosoma brucei PAB1-binding protein , putative 0.0013 0.0146 0.1067
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0057 0.0116
Echinococcus multilocularis bloom syndrome protein 0.0025 0.0367 0.0383
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0256 0.025
Brugia malayi AMP-binding enzyme family protein 0.0008 0.0057 0.0116
Trichomonas vaginalis AGC family protein kinase 0.0005 0.0002 0.0011
Schistosoma mansoni hypothetical protein 0.0049 0.082 0.1328
Echinococcus granulosus nervana 2 0.0008 0.0064 0.0103
Leishmania major importin beta-1 subunit, putative 0.0026 0.039 0.3053
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0006 0.0029 0.003
Schistosoma mansoni thyroid hormone receptor 0.0045 0.0746 0.1208
Echinococcus granulosus fructose 16 bisphosphate aldolase 0.0029 0.045 0.0729
Brugia malayi hypothetical protein 0.0131 0.2316 0.4786
Brugia malayi Protein kinase domain containing protein 0.0013 0.0151 0.0311
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0397 0.0362
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0021 0.0307 0.0497
Brugia malayi nuclear receptor RXR 0.0021 0.0307 0.0633
Plasmodium vivax ataxin-2 like protein, putative 0.0013 0.0146 0.0586
Brugia malayi tailless protein 0.0021 0.0307 0.0633
Trichomonas vaginalis alpha-glucosidase, putative 0.0012 0.0141 0.072
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0024 0.0354 0.0369
Trypanosoma cruzi DNA polymerase eta, putative 0.0027 0.0408 0.3217
Schistosoma mansoni blooms syndrome DNA helicase 0.0005 0.001 0.0016
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.0199 0.1529
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0011 0.0127 0.0941
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0017 0.0221 0.089
Trypanosoma cruzi DNA polymerase kappa, putative 0.0027 0.0415 0.3275
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.0018 0.0248 0.1924
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0015 0.0199 0.0804
Echinococcus multilocularis NADPH cytochrome P450 reductase 0.0007 0.0037 0.0038
Mycobacterium tuberculosis Conserved protein 0.0008 0.0069 0.0057
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0045 0.0746 0.1208
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0111 0.1958 1
Schistosoma mansoni hypothetical protein 0.0091 0.1583 0.2566
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0157 0.1157
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0005 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0021 0.0307 0.0497
Loa Loa (eye worm) hypothetical protein 0.0029 0.0453 0.0734
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0027 0.0415 0.0433
Toxoplasma gondii aurora kinase 0.0034 0.0537 0.2136
Plasmodium vivax fructose 1,6-bisphosphate aldolase, putative 0.0029 0.045 0.1818
Loa Loa (eye worm) hypothetical protein 0.001 0.0106 0.0171
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0011 0.0127 0.0941
Loa Loa (eye worm) glutathione reductase 0.0033 0.0525 0.0851
Loa Loa (eye worm) hypothetical protein 0.001 0.0107 0.0172
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0045 0.0746 0.1208
Trypanosoma brucei trypanothione reductase 0.0033 0.0525 0.4148
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0008 0.0071 0.0244
Plasmodium falciparum thioredoxin reductase 0.0011 0.0127 0.0458
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0397 0.3107
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0397 0.3107
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0009 0.0075 0.0525
Mycobacterium ulcerans N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB 0.0018 0.0248 0.0212
Treponema pallidum exodeoxyribonuclease (exoA) 0.0007 0.0043 0.0133
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0015 0.0199 0.0322
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0031 0.0481 0.0992
Brugia malayi exodeoxyribonuclease III family protein 0.0007 0.0043 0.0088
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0013 0.0151 0.0244
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0111 0.1958 1
Brugia malayi CXXC zinc finger family protein 0.0011 0.0116 0.0239
Entamoeba histolytica recQ family helicase, putative 0.0013 0.0157 0.0789
Trichomonas vaginalis AGC family protein kinase 0.0005 0.0002 0.0011
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0037 0.0604 0.055
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0076 0.1306 0.1339
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.257 0.4167
Brugia malayi Heterochromatin protein 1 0.0024 0.0351 0.0725
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0054 0.0913 0.088
Trichomonas vaginalis CAMK family protein kinase 0.0068 0.1173 0.5992
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0144 0.257 0.2685
Schistosoma mansoni ap endonuclease 0.0007 0.0043 0.0069
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0044 0.0726 0.3698
Entamoeba histolytica HEAT repeat domain containing protein 0.0006 0.0026 0.0122
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0023 0.0346 0.1351
Brugia malayi hypothetical protein 0.0006 0.0029 0.0059
Trichomonas vaginalis hypothetical protein 0.0006 0.0026 0.0133
Trichomonas vaginalis CAMK family protein kinase 0.0068 0.1173 0.5992
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0415 0.3255
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0044 0.0726 0.2931
Brugia malayi nuclear receptor RXR 0.0024 0.0354 0.0731
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0045 0.0746 0.1208
Loa Loa (eye worm) hypothetical protein 0.0014 0.018 0.029
Loa Loa (eye worm) AUR protein kinase 0.0034 0.0537 0.0869
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0013 0.016 0.057
Schistosoma mansoni hypothetical protein 0.001 0.0098 0.0157
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0008 0.0057 0.002
Echinococcus granulosus survival motor neuron protein 1 0.0268 0.4838 0.7845
Plasmodium vivax acetyl-CoA synthetase, putative 0.0008 0.0057 0.0227
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0005 0.0014 0.0001
Trypanosoma cruzi p450 reductase, putative 0.0007 0.0037 0.0213
Mycobacterium tuberculosis Mycothiol conjugate amidase Mca (mycothiol S-conjugate amidase) 0.053 0.9667 1
Plasmodium vivax protein arginine N-methyltransferase 1, putative 0.0005 0.0014 0.0054
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0011 0.0127 0.0941
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0054 0.0913 0.0862
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.018 0.0187
Trypanosoma brucei fructose-bisphosphate aldolase, glycosomal, putative 0.0029 0.045 0.3541
Entamoeba histolytica G protein alpha subunit, putative 0.0006 0.0029 0.0139
Echinococcus granulosus lysine specific demethylase 5A 0.0013 0.0148 0.0238
Trichomonas vaginalis importin beta-1, putative 0.0026 0.039 0.1992
Onchocerca volvulus 0.0081 0.1399 0.5989
Trypanosoma cruzi protein farnesyltransferase, putative 0.0042 0.068 0.5413
Schistosoma mansoni serine/threonine protein kinase 0.0005 0.0002 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0045 0.0746 0.154
Trypanosoma brucei DNA polymerase IV, putative 0.0027 0.0415 0.3255
Brugia malayi Bromodomain containing protein 0.0014 0.0172 0.0353
Leishmania major N-acetyl-D-acetylglucosaminylphosphatidylinositol deacetylase 0.0018 0.0248 0.19
Toxoplasma gondii exonuclease III APE 0.0007 0.0043 0.0133
Loa Loa (eye worm) hypothetical protein 0.0024 0.0354 0.0573
Trichomonas vaginalis CAMK family protein kinase 0.0068 0.1173 0.5992
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0008 0.0057 0.0375
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0111 0.1958 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0397 0.0642
Brugia malayi follicle stimulating hormone receptor 0.016 0.2866 0.5924
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0011 0.0123 0.0198
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0008 0.0069 0.0444
Entamoeba histolytica recQ family DNA helicase 0.0005 0.001 0.0042
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0032 0.0513 0.0535
Trypanosoma cruzi PAB1-binding protein , putative 0.0013 0.0146 0.1093
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0006 0.0032 0.0165
Brugia malayi MH2 domain containing protein 0.0045 0.075 0.1549
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0045 0.0746 0.154
Trypanosoma brucei hypothetical protein, conserved 0.0009 0.0074 0.049
Schistosoma mansoni sex comb on midleg homolog 0.0015 0.0186 0.03
Trypanosoma cruzi polo-like protein kinase, putative 0.0068 0.1173 0.9409
Brugia malayi Glycosyl hydrolases family 31 protein 0.0012 0.0141 0.029
Trypanosoma cruzi DNA polymerase eta, putative 0.0046 0.0753 0.6005
Echinococcus multilocularis nervana 2 0.0008 0.0064 0.0067
Brugia malayi Glycosyl hydrolases family 31 protein 0.0055 0.0933 0.1926
Plasmodium falciparum fructose-bisphosphate aldolase 0.0029 0.045 0.1774
Schistosoma mansoni cpg binding protein 0.0011 0.0116 0.0187
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0026 0.0397 0.0362
Leishmania major UDP-galactopyranose mutase 0.0016 0.0202 0.1523
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0007 0.0037 0.0184
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0012 0.0141 0.053
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0307 0.032
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0006 0.0029 0.0059
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0045 0.0746 0.0779
Trypanosoma cruzi protein farnesyltransferase, putative 0.0042 0.068 0.5413
Loa Loa (eye worm) hypothetical protein 0.0008 0.0071 0.0113
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0011 0.0127 0.051
Brugia malayi jmjC domain containing protein 0.0032 0.0513 0.1059
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0005 0.0014 0.0014
Schistosoma mansoni jumonji/arid domain-containing protein 0.0013 0.0148 0.0238
Echinococcus multilocularis muscleblind protein 1 0.0046 0.0761 0.0795
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0157 0.1157
Schistosoma mansoni alpha-glucosidase 0.0048 0.0791 0.1281
Schistosoma mansoni chromobox protein 0.0024 0.0351 0.0569
Trypanosoma brucei aurora B kinase 0.0034 0.0537 0.4241
Trypanosoma brucei lanosterol synthase 0.0023 0.0344 0.2681
Onchocerca volvulus 0.001 0.0107 0.0339
Leishmania major protein kinase, putative 0.0034 0.0537 0.4241
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0006 0.0019 0.0019
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0057 0.002
Loa Loa (eye worm) hypothetical protein 0.0045 0.0746 0.1208
Trichomonas vaginalis AGC family protein kinase 0.0013 0.0151 0.0773
Loa Loa (eye worm) DR-78 0.0021 0.0307 0.0497
Mycobacterium tuberculosis Probable oxidoreductase 0.0084 0.1462 0.15
Leishmania major DNA polymerase eta, putative 0.0046 0.0753 0.5994
Brugia malayi steroid hormone receptor 0.0045 0.0746 0.154
Echinococcus granulosus lysine specific histone demethylase 1A 0.0016 0.0202 0.0326
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0048 0.0803 0.3215
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0415 0.3255
Brugia malayi serine/threonine kinase 12 0.0034 0.0537 0.1108
Trichomonas vaginalis CAMK family protein kinase 0.0068 0.1173 0.5992
Brugia malayi Importin beta-1 subunit 0.0032 0.0501 0.1034
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0005 0.0002 0.0002
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0032 0.0504 0.0508
Loa Loa (eye worm) hypothetical protein 0.0006 0.0029 0.0046
Echinococcus granulosus muscleblind protein 0.0046 0.0761 0.1233
Echinococcus multilocularis peregrin 0.0014 0.0172 0.0179
Schistosoma mansoni serine/threonine protein kinase 0.0005 0.0002 0.0002
Echinococcus multilocularis nervana 2 0.0008 0.0064 0.0067
Brugia malayi SWIRM domain containing protein 0.0016 0.0202 0.0415
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0011 0.0127 0.009
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0021 0.0307 0.0497
Echinococcus granulosus peregrin 0.0014 0.0172 0.0277
Mycobacterium ulcerans mycothiol conjugate amidase Mca 0.0548 1 1
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0021 0.0307 0.032
Echinococcus granulosus microtubule associated protein 2 0.0255 0.4608 0.7472
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0072 0.1235 0.1185
Mycobacterium tuberculosis N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB (GlcNAc-Ins deacetylase) 0.0018 0.0248 0.0243
Brugia malayi mbt repeat family protein 0.0015 0.0186 0.0382
Mycobacterium ulcerans hypothetical protein 0.0026 0.0397 0.0362
Trichomonas vaginalis AGC family protein kinase 0.0013 0.0151 0.0773
Wolbachia endosymbiont of Brugia malayi peptide deformylase 0.0139 0.2475 1
Schistosoma mansoni cpg binding protein 0.0012 0.0128 0.0206
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0006 0.0029 0.0046
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0016 0.0202 0.0326
Loa Loa (eye worm) hypothetical protein 0.0045 0.0746 0.1208
Echinococcus granulosus bloom syndrome protein 0.0025 0.0367 0.0594
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0415 0.3255
Echinococcus granulosus histone acetyltransferase KAT2B 0.0048 0.0803 0.13
Echinococcus multilocularis chromobox protein 1 0.0024 0.0351 0.0366
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0068 0.1173 0.1225
Echinococcus granulosus transportin 1 0.0006 0.0026 0.0041
Loa Loa (eye worm) hypothetical protein 0.0016 0.0202 0.0326
Schistosoma mansoni ran 0.0023 0.0346 0.0561
Trichomonas vaginalis sulfite reductase, putative 0.0007 0.0037 0.0187
Trichomonas vaginalis AGC family protein kinase 0.0034 0.0537 0.274
Trypanosoma brucei glucosidase, putative 0.0012 0.0141 0.1031
Trypanosoma cruzi Protein kinase B 0.0009 0.0075 0.0525
Mycobacterium tuberculosis Probable polypeptide deformylase Def (PDF) (formylmethionine deformylase) 0.0139 0.2475 0.2549
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0008 0.0057 0.002
Plasmodium falciparum glutathione reductase 0.0011 0.0127 0.0458
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0006 0.0029 0.0046
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0024 0.0358 0.058
Brugia malayi G-protein alpha subunit 0.0006 0.0029 0.0059
Loa Loa (eye worm) hypothetical protein 0.002 0.0275 0.0445
Brugia malayi Nuclear hormone receptor E75 0.0021 0.0307 0.0633
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0102 0.0371
Echinococcus granulosus thyroid hormone receptor alpha 0.0021 0.0307 0.0497
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0111 0.1958 1
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0015 0.0199 0.0208
Plasmodium vivax acyl-CoA synthetase, putative 0.002 0.0275 0.111
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0026 0.0397 0.0362
Entamoeba histolytica hypothetical protein 0.0048 0.0796 0.4055
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0049 0.082 0.1328
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0034 0.0537 0.2167
Trypanosoma cruzi aurora B kinase, putative 0.0034 0.0537 0.4258
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0008 0.0057 0.002
Loa Loa (eye worm) isocitrate dehydrogenase 0.0005 0.0014 0.0022
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0042 0.0684 0.3494
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0008 0.0057 0.0044
Trichomonas vaginalis AGC family protein kinase 0.0005 0.0002 0.0011
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0008 0.0069 0.0472
Leishmania major DNA polymerase kappa, putative 0.0027 0.0415 0.3256
Toxoplasma gondii hypothetical protein 0.0015 0.0199 0.0767
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0045 0.0746 0.1208
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0044 0.0726 0.1499
Brugia malayi nuclear receptor NHR-88 0.0021 0.0307 0.0633
Trichomonas vaginalis DNA polymerase eta, putative 0.0027 0.0415 0.212
Loa Loa (eye worm) hypothetical protein 0.0032 0.0501 0.0811
Trypanosoma brucei unspecified product 0.0019 0.026 0.1997
Brugia malayi serine/threonine protein kinase 6 0.0034 0.0537 0.1108
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0045 0.0746 0.1208
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0072 0.1235 0.2002
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0007 0.0043 0.0266
Loa Loa (eye worm) hypothetical protein 0.0015 0.0186 0.03
Echinococcus granulosus protein farnesyltransferase subunit beta 0.0042 0.068 0.1101
Schistosoma mansoni hypothetical protein 0.0048 0.0796 0.1289
Echinococcus multilocularis histone acetyltransferase MYST2 0.0017 0.0223 0.0232
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0011 0.0127 0.009
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0005 0.0002 0.0002
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0068 0.1173 0.9407
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.039 0.3073
Schistosoma mansoni alpha-glucosidase 0.0048 0.0791 0.1281
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0011 0.0127 0.0343
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0023 0.0346 0.0715
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0043 0.0699 0.1133
Mycobacterium tuberculosis Conserved hypothetical protein 0.0027 0.0415 0.0416
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0009 0.0074 0.0063
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0021 0.0306 0.0494
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0017 0.0223 0.0459
Schistosoma mansoni thyroid hormone receptor 0.0045 0.0746 0.1208
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.026 0.1997
Schistosoma mansoni terminal deoxycytidyl transferase 0.0027 0.0415 0.0672
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0005 0.0014 0.0029
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0008 0.0057 0.0347
Brugia malayi nuclear hormone receptor family member nhr-6 0.0021 0.0307 0.0633
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0011 0.0127 0.0458
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0023 0.0346 0.1398
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0011 0.0127 0.026
Brugia malayi photoreceptor-specific nuclear receptor 0.0045 0.0746 0.154
Schistosoma mansoni kinase 0.0035 0.0558 0.0904
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0008 0.0057 0.0044
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0155 0.2773 0.5731
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0006 0.0029 0.0046
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0006 0.0029 0.0059
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0008 0.0057 0.0347
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0026 0.0397 0.0362
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0009 0.0074 0.026
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0044 0.0726 0.0758
Loa Loa (eye worm) hypothetical protein 0.0045 0.0746 0.1208
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0045 0.0746 0.154
Brugia malayi p70 ribosomal S6 kinase beta 0.0013 0.0151 0.0311
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.0042 0.068 0.347
Schistosoma mansoni protein arginine N-methyltransferase 1 0.0005 0.0014 0.0021
Entamoeba histolytica deoxycytidyl transferase, putative 0.0027 0.0415 0.2111
Echinococcus multilocularis N acetylglucosaminyl phosphatidylinositol 0.0018 0.0248 0.0259
Echinococcus multilocularis musashi 0.003 0.0463 0.0483
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0042 0.0684 0.2734
Brugia malayi serine/threonine-protein kinase plk-2 0.0068 0.1173 0.2424
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0006 0.0029 0.0046
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0059 0.1006 0.163
Schistosoma mansoni intermediate filament proteins 0.003 0.0463 0.075
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0011 0.0127 0.0941
Echinococcus multilocularis protoporphyrinogen oxidase 0.0072 0.1235 0.129
Schistosoma mansoni lamin 0.003 0.0463 0.075
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0015 0.0199 0.1529
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0006 0.0029 0.0046
Echinococcus multilocularis ecdysone induced protein 78C 0.0045 0.0746 0.0779
Trypanosoma brucei rac serine-threonine kinase, putative 0.0013 0.0151 0.1114
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0045 0.0746 0.0779
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0006 0.0029 0.0046
Echinococcus multilocularis translational activator gcn1 0.0006 0.0026 0.0027
Mycobacterium ulcerans monoamine oxidase 0.0016 0.0202 0.0166
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0057 0.002
Echinococcus multilocularis NADPH dependent diflavin oxidoreductase 1 0.0007 0.0037 0.0038
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0059 0.1006 0.105
Leishmania major fructose-1,6-bisphosphate aldolase 0.0029 0.045 0.3542
Schistosoma mansoni jumonji domain containing protein 0.0026 0.039 0.0631
Schistosoma mansoni cytochrome P450 reductase 0.0007 0.0037 0.0058
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0042 0.068 0.347
Echinococcus multilocularis 0.0016 0.0202 0.021
Brugia malayi RNA recognition motif domain containing protein 0.0024 0.0358 0.0739
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0016 0.0202 0.0813
Schistosoma mansoni tar DNA-binding protein 0.0024 0.0358 0.058
Plasmodium vivax importin-beta 2, putative 0.0032 0.0501 0.2023
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0397 0.0362
Toxoplasma gondii hypothetical protein 0.0139 0.2475 1
Mycobacterium ulcerans dehydrogenase 0.0016 0.0202 0.0166
Schistosoma mansoni inositol monophosphatase 0.0042 0.0684 0.1108
Schistosoma mansoni hypothetical protein 0.034 0.6167 1
Entamoeba histolytica Rab geranylgeranyltransferase beta subunit, putative 0.0011 0.0123 0.0616
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.0018 0.0248 0.1924
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0007 0.0037 0.0024
Echinococcus granulosus chromobox protein 1 0.0024 0.0351 0.0569
Schistosoma mansoni serine/threonine protein kinase 0.0005 0.0002 0.0002
Brugia malayi serine/threonine-protein kinase 6 0.0034 0.0537 0.1108
Loa Loa (eye worm) phosphatidylinositol glycan anchor biosynthesis protein 0.0018 0.0248 0.0401
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0111 0.1958 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0307 0.0497
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0076 0.1306 0.1257
Loa Loa (eye worm) fructose-bisphosphate aldolase 2 0.0029 0.045 0.0729
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0008 0.0057 0.0188
Leishmania major phosphopantetheinyl transferase-like protein 0.0009 0.0074 0.0491
Schistosoma mansoni N-acetylglucosaminyl-phosphatidylinositol de-n-acetylase 0.0018 0.0248 0.0401
Brugia malayi Steroid receptor seven-up type 2 0.0045 0.0746 0.154
Plasmodium falciparum geranylgeranyl transferase type2 beta subunit, putative 0.0011 0.0123 0.0442
Echinococcus granulosus translational activator gcn1 0.0006 0.0026 0.0041
Trypanosoma brucei DNA polymerase eta, putative 0.0046 0.0753 0.5993
Schistosoma mansoni steroid hormone receptor ad4bp 0.0045 0.0746 0.1208
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0111 0.1958 1
Echinococcus granulosus NADPH cytochrome P450 reductase 0.0007 0.0037 0.0058
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0008 0.0069 0.0032
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0111 0.1958 1
Schistosoma mansoni ran 0.0023 0.0346 0.0561
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0021 0.0307 0.0633
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.016 0.0816
Loa Loa (eye worm) hypothetical protein 0.0011 0.0123 0.0198
Schistosoma mansoni acetyl-CoA synthetase 0.0008 0.0057 0.0091
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.0463 0.075
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0011 0.0127 0.0914
Onchocerca volvulus 0.0011 0.0116 0.0379
Brugia malayi Hr1 repeat family protein 0.0005 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0017 0.0228 0.0369
Echinococcus granulosus snurportin 1 0.034 0.6167 1
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.034 0.6167 1
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.1246 1
Loa Loa (eye worm) hypothetical protein 0.0155 0.2773 0.4496
Schistosoma mansoni fructose 16-bisphosphate aldolase 0.0029 0.045 0.0729
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0141 0.1057
Echinococcus granulosus histone acetyltransferase KAT2B 0.0159 0.2848 0.4617
Onchocerca volvulus 0.003 0.0463 0.1897
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0011 0.0123 0.0198
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0011 0.0127 0.0915
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0032 0.0165
Echinococcus granulosus Protein kinase C brain isozyme 0.0005 0.0002 0.0002
Trichomonas vaginalis chromobox protein, putative 0.0014 0.0178 0.091
Loa Loa (eye worm) AUR protein kinase 0.0034 0.0537 0.0869
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0045 0.0746 0.1208
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0021 0.0307 0.0497
Entamoeba histolytica protein kinase, putative 0.0013 0.0151 0.0762
Brugia malayi polk-prov protein 0.0008 0.0071 0.0144
Loa Loa (eye worm) hypothetical protein 0.0026 0.0397 0.0642
Echinococcus granulosus ATP dependent DNA helicase Q1 0.001 0.0102 0.0164
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0008 0.0057 0.0375
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0045 0.0746 0.1208
Loa Loa (eye worm) hypothetical protein 0.0016 0.0202 0.0326
Echinococcus multilocularis lamin dm0 0.003 0.0463 0.0483
Echinococcus multilocularis Rab geranylgeranyltransferase, beta subunit 0.0011 0.0123 0.0127
Treponema pallidum NADH oxidase 0.0011 0.0127 0.0472
Trichomonas vaginalis chromobox protein, putative 0.0014 0.0178 0.091
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0006 0.0029 0.0059
Trichomonas vaginalis AGC family protein kinase 0.0013 0.0151 0.0773
Echinococcus granulosus NADPH dependent diflavin oxidoreductase 1 0.0007 0.0037 0.0058
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0045 0.0746 0.154
Loa Loa (eye worm) hypothetical protein 0.0016 0.0202 0.0326
Echinococcus granulosus citrate lyase subunit beta protein 0.0008 0.0069 0.011
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0032 0.0165
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0084 0.1462 0.15
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0009 0.0074 0.0299
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0045 0.0746 0.1208
Echinococcus granulosus geminin 0.0192 0.3443 0.5582
Trichomonas vaginalis mercuric reductase, putative 0.0011 0.0127 0.0647
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.001 0.0106 0.0171
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase 0.0029 0.045 0.047
Loa Loa (eye worm) hypothetical protein 0.0044 0.0726 0.1176
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0015 0.0186 0.03
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0027 0.0415 0.0672
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0415 0.3255
Plasmodium falciparum protein farnesyltransferase subunit beta 0.0042 0.068 0.2705
Brugia malayi Uncharacterized LmbE-like protein, COG2120 containing protein 0.0018 0.0248 0.0511
Loa Loa (eye worm) steroid hormone receptor 0.0045 0.0746 0.1208
Mycobacterium tuberculosis Possible oxidoreductase 0.0016 0.0202 0.0194
Loa Loa (eye worm) hypothetical protein 0.0024 0.0354 0.0573
Trichomonas vaginalis AGC family protein kinase 0.0005 0.0002 0.0011
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0007 0.0037 0.0184
Echinococcus multilocularis polycomb protein SCMH1 0.0015 0.0186 0.0193
Loa Loa (eye worm) hypothetical protein 0.0021 0.0307 0.0497
Schistosoma mansoni tar DNA-binding protein 0.0024 0.0358 0.058
Loa Loa (eye worm) nuclear hormone receptor 0.0021 0.0307 0.0497
Echinococcus granulosus cpg binding protein 0.0012 0.0128 0.0206
Brugia malayi hypothetical protein 0.0021 0.0307 0.0633
Echinococcus granulosus SAM and MBT domain containing protein 0.0015 0.0186 0.03
Trichomonas vaginalis CAMK family protein kinase 0.0068 0.1173 0.5992
Trypanosoma brucei DNA damage repair protein, putative 0.0008 0.0071 0.0458
Loa Loa (eye worm) hypothetical protein 0.0008 0.0069 0.0111
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0045 0.0746 0.3134
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0008 0.0057 0.0044
Mycobacterium tuberculosis Probable reductase 0.0076 0.1306 0.1339
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0011 0.0127 0.0914
Schistosoma mansoni hypothetical protein 0.0055 0.0919 0.149
Mycobacterium ulcerans aldehyde dehydrogenase 0.0032 0.0504 0.0469
Giardia lamblia PHD finger protein 15 0.001 0.0098 0.0387
Echinococcus granulosus serine:threonine protein kinase N2 0.0005 0.0002 0.0002
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0045 0.0746 0.154
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0008 0.0057 0.002
Echinococcus multilocularis rac serine:threonine kinase 0.0009 0.0075 0.0078
Plasmodium vivax conserved Plasmodium protein, unknown function 0.003 0.0472 0.1906
Loa Loa (eye worm) hypothetical protein 0.0046 0.0753 0.1219
Loa Loa (eye worm) hypothetical protein 0.0046 0.0761 0.1233
Echinococcus multilocularis lamin 0.003 0.0463 0.0483
Brugia malayi hypothetical protein 0.0024 0.0354 0.0731
Loa Loa (eye worm) hypothetical protein 0.0045 0.0746 0.1208
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0048 0.0796 0.1289
Brugia malayi Inositol-1 0.0042 0.0684 0.1413
Trypanosoma brucei protein farnesyltransferase beta subunit 0.0042 0.068 0.54
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0008 0.0057 0.0044
Trichomonas vaginalis CAMK family protein kinase 0.0034 0.0542 0.2765
Schistosoma mansoni nuclear receptor nhr-48 0.0021 0.0307 0.0497
Brugia malayi Calcitonin receptor-like protein seb-1 0.0155 0.2773 0.5731
Plasmodium vivax DNA repair protein REV1, putative 0.0008 0.0071 0.0283
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0045 0.0746 0.154
Schistosoma mansoni sex comb on midleg homolog 0.0015 0.0186 0.03
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0045 0.0746 0.154
Echinococcus multilocularis L aminoadipate semialdehyde 0.0031 0.0481 0.0502
Loa Loa (eye worm) hypothetical protein 0.0021 0.0307 0.0497
Mycobacterium leprae conserved hypothetical protein 0.0009 0.0074 0.0018
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0006 0.0029 0.003
Onchocerca volvulus Serine\/threonine kinase homolog 0.0068 0.1173 0.5004
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0005 0.0007 0.0025
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0008 0.0069 0.0057
Trichomonas vaginalis AGC family protein kinase 0.0034 0.0537 0.274
Trichomonas vaginalis DNA helicase recq, putative 0.0025 0.0367 0.1873
Trichomonas vaginalis DNA helicase recq, putative 0.0013 0.0157 0.08
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0021 0.0307 0.032
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0032 0.0504 0.3976
Trypanosoma cruzi geranylgeranyl transferase type II beta subunit, putative 0.0011 0.0123 0.0908
Onchocerca volvulus 0.0021 0.0307 0.1215
Giardia lamblia Glucosamine-6-phosphate isomerase, putative 0.0018 0.0248 0.1164
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.002 0.0279 0.0452
Mycobacterium ulcerans DNA polymerase IV 0.0027 0.0415 0.038
Loa Loa (eye worm) acetyltransferase 0.0164 0.2933 0.4755
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0005 0.0002 0.0002
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0008 0.0057 0.0279
Echinococcus multilocularis importin 5 0.0006 0.0026 0.0027
Schistosoma mansoni amine oxidase 0.0016 0.0202 0.0326
Brugia malayi ecdysone receptor 0.0021 0.0307 0.0633
Leishmania major GTP-binding protein, putative 0.0023 0.0346 0.2697
Schistosoma mansoni microtubule-associated protein tau 0.0255 0.4608 0.7472
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0008 0.0057 0.0174
Echinococcus granulosus serine threonine protein kinase nrc 0.0009 0.0075 0.0121
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0045 0.0746 0.154
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0011 0.0127 0.0941
Toxoplasma gondii PHD-finger domain-containing protein 0.001 0.0098 0.0355
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0006 0.0029 0.0059
Loa Loa (eye worm) hypothetical protein 0.0031 0.0481 0.0779
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0006 0.0029 0.015
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0023 0.0346 0.0561
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0009 0.0075 0.0078
Toxoplasma gondii PHD-finger domain-containing protein 0.001 0.0098 0.0355
Echinococcus granulosus protein arginine methyltransferase 0.0005 0.0014 0.0021
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0005 0.0014 0.0014
Leishmania major alpha glucosidase II subunit, putative 0.0012 0.0141 0.1032
Entamoeba histolytica geranylgeranyl transferase beta subunit 0.0011 0.0123 0.0616
Trypanosoma cruzi polo-like protein kinase, putative 0.0068 0.1173 0.9409
Echinococcus granulosus ecdysone induced protein 78C 0.0045 0.0746 0.1208
Brugia malayi latrophilin 2 splice variant baaae 0.0106 0.1869 0.3862
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0009 0.0074 0.0246
Echinococcus multilocularis Glutaredoxin protein 5 0.0009 0.0073 0.0075
Echinococcus granulosus protein kinase c iota type 0.0005 0.0002 0.0002
Brugia malayi F/Y-rich N-terminus family protein 0.0007 0.0043 0.0088
Loa Loa (eye worm) RNA binding protein 0.0024 0.0358 0.058
Chlamydia trachomatis peptide deformylase 0.0139 0.2475 1
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0008 0.0069 0.0351
Echinococcus granulosus tar DNA binding protein 0.0024 0.0358 0.058
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0008 0.0057 0.0059
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase 0.0029 0.045 0.047
Brugia malayi fructose-bisphosphate aldolase 2 0.0029 0.045 0.093
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0006 0.0029 0.015
Entamoeba histolytica recQ family helicase, putative 0.0005 0.0007 0.0023
Schistosoma mansoni myelin transcription factor 1 myt1 0.0017 0.0223 0.036
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0093 0.1627 0.1671
Echinococcus multilocularis FTZ F1 alpha 0.0045 0.0746 0.0779
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.001 0.0106 0.0171
Loa Loa (eye worm) hypothetical protein 0.0021 0.0307 0.0497
Schistosoma mansoni nuclear receptor 0.0021 0.0307 0.0497
Plasmodium falciparum thioredoxin reductase 0.0033 0.0525 0.2078
Trypanosoma cruzi DNA damage repair protein, putative 0.0008 0.0071 0.0486
Onchocerca volvulus Alhambra homolog 0.001 0.0098 0.0299
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.039 0.1992
Trypanosoma cruzi UDP-galactopyranose mutase 0.0016 0.0202 0.1547
Mycobacterium leprae PROBABLE POLYPEPTIDE DEFORMYLASE DEF (PDF) (FORMYLMETHIONINE DEFORMYLASE) 0.0139 0.2475 0.2432
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0684 0.5452
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0011 0.0127 0.0458
Plasmodium falciparum geranylgeranyltransferase, putative 0.0011 0.0123 0.0442
Loa Loa (eye worm) AGC/NDR protein kinase 0.0005 0.0002 0.0002
Onchocerca volvulus 0.0026 0.0397 0.1607
Trypanosoma brucei DNA polymerase kappa, putative 0.0008 0.0071 0.0458
Trichomonas vaginalis AGC family protein kinase 0.0034 0.0537 0.274
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0006 0.0029 0.015
Echinococcus multilocularis lysosomal alpha glucosidase 0.0055 0.0933 0.0974
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0684 0.5438
Loa Loa (eye worm) CXXC zinc finger family protein 0.0011 0.0116 0.0187
Plasmodium vivax transportin, putative 0.0006 0.0026 0.0103
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0045 0.0746 0.1208
Plasmodium falciparum importin beta, putative 0.0032 0.0501 0.1979
Entamoeba histolytica acetyltransferase, GNAT family 0.0044 0.0729 0.3714
Mycobacterium ulcerans acyl-CoA synthetase 0.0008 0.0057 0.002
Echinococcus granulosus FTZ F1 alpha 0.0045 0.0746 0.1208
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0021 0.0306 0.027
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0415 0.3255
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0006 0.0029 0.0046
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0044 0.0726 0.1176
Entamoeba histolytica serine/threonine protein kinase, putative 0.0068 0.1173 0.5987
Leishmania major NADPH-cytochrome p450 reductase-like protein 0.0007 0.0037 0.0185
Schistosoma mansoni serine/threonine kinase 0.0005 0.0002 0.0002
Echinococcus multilocularis GPCR, family 2 0.0049 0.082 0.0856
Mycobacterium ulcerans peptide deformylase 0.0139 0.2475 0.2447
Trypanosoma brucei DNA polymerase kappa, putative 0.0008 0.0071 0.0458
Schistosoma mansoni aldehyde dehydrogenase 0.0032 0.0504 0.0816
Toxoplasma gondii Rab geranylgeranyl transferase type II beta subunit, putative 0.0011 0.0123 0.0456
Trichomonas vaginalis CAMK family protein kinase 0.0034 0.0542 0.2765
Giardia lamblia Prenyltransferase 0.0042 0.068 0.3392
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0008 0.0057 0.0375
Loa Loa (eye worm) hypothetical protein 0.0013 0.016 0.0258
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0027 0.0408 0.1613
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0346 0.2718
Leishmania major DNA polymerase kappa, putative 0.0008 0.0071 0.0459
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0018 0.0248 0.1267
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.001 0.0106 0.011
Brugia malayi protein kinase C II. 0.0005 0.0002 0.0003
Onchocerca volvulus Huntingtin homolog 0.0131 0.2316 1
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.0199 0.1529
Giardia lamblia Rab geranylgeranyltransferase 0.0015 0.0199 0.0912
Loa Loa (eye worm) AUR protein kinase 0.0034 0.0537 0.0869
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0042 0.068 0.347
Schistosoma mansoni protein farnesyltransferase subunit beta 0.0042 0.068 0.1101

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) In vitro immunosuppressive activity by splenocyte mitogenesis assay in spleen cells from BDF1 female mice at 1 pM to 10 microM concentration; not active ChEMBL. No reference
Activity (functional) 0 In vitro immunosuppressive activity by splenocyte mitogenesis assay in spleen cells from BDF1 female mice at 1 pM to 10 microM concentration; not active ChEMBL. No reference
Ki app (binding) = 15 nM Binding affinity for FK506 binding protein ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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