Detailed information for compound 976448

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 292.375 | Formula: C19H20N2O
  • H donors: 0 H acceptors: 1 LogP: 3.54 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCC(=O)N1N=C(CC1c1ccccc1)c1ccc(cc1)C
  • InChi: 1S/C19H20N2O/c1-3-19(22)21-18(16-7-5-4-6-8-16)13-17(20-21)15-11-9-14(2)10-12-15/h4-12,18H,3,13H2,1-2H3
  • InChiKey: MXAHFTJVXFIACF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Bos taurus Monoamine oxidase A Starlite/ChEMBL References
Bos taurus Monoamine oxidase B Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) Get druggable targets OG5_130722 All targets in OG5_130722
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH Get druggable targets OG5_130722 All targets in OG5_130722
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH Get druggable targets OG5_130722 All targets in OG5_130722
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Dictyostelium discoideum amine oxidase Monoamine oxidase A   527 aa 492 aa 29.9 %
Dictyostelium discoideum hypothetical protein Monoamine oxidase A   527 aa 542 aa 21.6 %
Dictyostelium discoideum hypothetical protein Monoamine oxidase A   527 aa 546 aa 21.6 %
Brugia malayi amine oxidase, flavin-containing family protein Monoamine oxidase A   527 aa 472 aa 21.4 %
Onchocerca volvulus Mitochondrial fission process protein 1 homolog Monoamine oxidase B   520 aa 454 aa 21.4 %
Dictyostelium discoideum hypothetical protein Monoamine oxidase A   527 aa 552 aa 18.5 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus phd:f box containing protein 0.0047 0.0104 0.0104
Trypanosoma cruzi cdc2-related kinase 3 0.0099 0.0352 0.0784
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0049 0.0116 0.0187
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0071 0.0115
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0191 0.0191
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.1359 0.2186
Loa Loa (eye worm) acetyltransferase 0.0312 0.1351 0.2174
Echinococcus granulosus mixed lineage leukemia protein mll 0.004 0.0074 0.0074
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0049 0.0116 0.026
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0049 0.0116 0.0187
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0206 0.0852 0.0852
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0026 0.0007 0.0011
Brugia malayi Glycosyl hydrolases family 31 protein 0.0056 0.0147 0.0237
Schistosoma mansoni phosphatidylserine receptor 0.0047 0.0104 0.0104
Trypanosoma brucei cdc2-related kinase 3 0.0099 0.0352 0.0767
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0086 0.0289 0.2748
Loa Loa (eye worm) 6-phosphofructokinase 0.0228 0.0959 0.1543
Echinococcus multilocularis cyclin dependent kinase 1 0.0099 0.0352 0.0352
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0086 0.0289 0.064
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0026 0.0007 0.0007
Schistosoma mansoni cell adhesion molecule 0.0028 0.0015 0.0015
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0062 0.0175 0.1286
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0034 0.0042 0.006
Toxoplasma gondii ABC1 family protein 0.0038 0.0062 0.0494
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0097 0.034 0.2695
Schistosoma mansoni jumonji/arid domain-containing protein 0.0189 0.0776 0.0776
Echinococcus granulosus GA binding protein alpha chain 0.0142 0.0551 0.0551
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.1359 0.2186
Schistosoma mansoni ets-related 0.043 0.1907 0.1907
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0049 0.0116 0.0116
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0182 0.0743 0.23
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0049 0.0116 0.0187
Loa Loa (eye worm) hypothetical protein 0.0118 0.0439 0.0706
Leishmania major DNA damage repair protein, putative 0.003 0.0025 0.0021
Echinococcus multilocularis L aminoadipate semialdehyde 0.0264 0.1129 0.1129
Echinococcus granulosus phosphoglycerate kinase 1 0.0182 0.0743 0.0743
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0057 0.0154 0.0248
Schistosoma mansoni bromodomain containing protein 0.0029 0.002 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.028 0.045
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0038 0.0062
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0025 0.0003 0.0028
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0178 0.0722 0.0722
Loa Loa (eye worm) hypothetical protein 0.0029 0.0019 0.0031
Loa Loa (eye worm) PHD-finger family protein 0.0093 0.0321 0.0516
Schistosoma mansoni cpg binding protein 0.0144 0.0564 0.0564
Trypanosoma brucei polo-like protein kinase 0.0201 0.0833 0.1862
Loa Loa (eye worm) jmjC domain-containing protein 0.0047 0.0104 0.0168
Entamoeba histolytica hypothetical protein 0.0032 0.0034 0.025
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0628 0.2843 1
Onchocerca volvulus 0.0309 0.134 0.2999
Echinococcus multilocularis Chromobox protein 3 0.0025 0.000000024027 0.000000024027
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0025 0.004
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0199 0.0821 0.0821
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0454 0.2024 0.4575
Loa Loa (eye worm) PHD-finger family protein 0.0063 0.0183 0.0294
Schistosoma mansoni lamin 0.0029 0.0022 0.0022
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.0007 0.0011
Schistosoma mansoni transcription factor LCR-F1 0.0032 0.0034 0.0034
Echinococcus granulosus lysine specific histone demethylase 1A 0.0051 0.0122 0.0122
Brugia malayi Heterochromatin protein 1 0.015 0.059 0.0949
Toxoplasma gondii aldehyde dehydrogenase 0.0186 0.0762 0.6039
Echinococcus multilocularis neuroglian 0.0026 0.0008 0.0008
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0086 0.0289 0.0622
Trypanosoma brucei DNA polymerase kappa, putative 0.0125 0.0472 0.1039
Schistosoma mansoni intermediate filament proteins 0.0029 0.0022 0.0022
Schistosoma mansoni hypothetical protein 0.0032 0.0034 0.0034
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0201 0.0833 0.1862
Trichomonas vaginalis alpha-glucosidase, putative 0.015 0.0589 0.0948
Schistosoma mansoni serine/threonine protein kinase 0.0099 0.0352 0.0352
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0199 0.0821 0.0821
Echinococcus granulosus lysine specific histone demethylase 1A 0.0051 0.0122 0.0122
Trichomonas vaginalis esterase, putative 0.0038 0.0062 0.01
Brugia malayi hypothetical protein 0.0026 0.0007 0.0011
Brugia malayi hypothetical protein 0.0032 0.0034 0.0055
Plasmodium vivax flap endonuclease 1, putative 0.0028 0.0016 0.0151
Trypanosoma brucei hypothetical protein, conserved 0.0208 0.0861 0.1927
Schistosoma mansoni lozenge 0.006 0.0165 0.0165
Toxoplasma gondii phosphofructokinase PFKII 0.0062 0.0175 0.1385
Trypanosoma cruzi DNA damage repair protein, putative 0.003 0.0025 0.004
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0049 0.0116 0.0187
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0038 0.0062
Loa Loa (eye worm) hypothetical protein 0.0178 0.0722 0.1161
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0717 0.3261 0.5225
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0086 0.0289 0.2682
Schistosoma mansoni phosphoglycerate kinase 0.0182 0.0743 0.0743
Echinococcus granulosus zinc finger protein 0.0076 0.0241 0.0241
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.0218 0.0478
Onchocerca volvulus 0.039 0.1722 0.3852
Plasmodium falciparum flap endonuclease 1 0.0028 0.0016 0.0151
Echinococcus granulosus neutral alpha glucosidase AB 0.015 0.0589 0.0589
Schistosoma mansoni 6-phosphofructokinase 0.0228 0.0959 0.0959
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.0218 0.0478
Schistosoma mansoni myelin transcription factor 1 myt1 0.0058 0.0158 0.0158
Schistosoma mansoni importin beta-1 0.0029 0.0021 0.0021
Trichomonas vaginalis CMGC family protein kinase 0.0217 0.0906 0.1458
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.1359 0.2186
Schistosoma mansoni RAR-like nuclear receptor 0.0049 0.0116 0.0116
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0186 0.0762 0.2364
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0038 0.0062
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0201 0.0833 0.0833
Brugia malayi ImpB/MucB/SamB family protein 0.0096 0.0338 0.0544
Leishmania major DNA polymerase eta, putative 0.0057 0.0154 0.0314
Loa Loa (eye worm) hypothetical protein 0.0147 0.0575 0.0925
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.0042 0.0079
Echinococcus granulosus flap endonuclease 1 0.0028 0.0016 0.0016
Brugia malayi Bloom's syndrome protein homolog 0.0094 0.0327 0.0526
Trichomonas vaginalis DNA helicase recq, putative 0.0094 0.0327 0.0526
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0022 0.0035
Plasmodium falciparum glutathione reductase 0.0248 0.1051 1
Brugia malayi intermediate filament protein 0.0029 0.0022 0.0035
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0071 0.0218 0.0218
Trypanosoma brucei phosphoglycerate kinase 0.0067 0.02 0.0419
Echinococcus granulosus dna polymerase kappa 0.0125 0.0472 0.0472
Brugia malayi acetyltransferase, GNAT family protein 0.0312 0.1351 0.2174
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0058 0.0158 0.0158
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0086 0.0289 0.0426
Onchocerca volvulus 0.0051 0.0122 0.0274
Brugia malayi ecdysteroid receptor 0.0049 0.0116 0.0187
Trichomonas vaginalis phosphofructokinase, putative 0.0062 0.0175 0.0281
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0052 0.0131 0.0131
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0086 0.0289 0.2748
Schistosoma mansoni 6-phosphofructokinase 0.0228 0.0959 0.0959
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.015 0.0589 0.0948
Chlamydia trachomatis phosphoglycerate kinase 0.0182 0.0743 1
Schistosoma mansoni hypothetical protein 0.0315 0.1367 0.1367
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0126 0.0475 0.3767
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0059 0.0162 0.1288
Schistosoma mansoni aldehyde dehydrogenase 0.0186 0.0762 0.0762
Brugia malayi beta-lactamase family protein 0.0038 0.0062 0.01
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0086 0.0289 0.0289
Schistosoma mansoni hypothetical protein 0.0364 0.16 0.16
Plasmodium vivax glycogen synthase kinase 3, putative 0.0217 0.0906 0.8622
Loa Loa (eye worm) hypothetical protein 0.0044 0.0093 0.015
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0062 0.006
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0186 0.0762 0.1701
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0312 0.1351 0.1351
Brugia malayi hypothetical protein 0.0475 0.2119 0.3409
Echinococcus multilocularis protein kinase shaggy 0.0217 0.0906 0.0906
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0367 0.161 0.161
Toxoplasma gondii histone lysine methyltransferase SET1 0.0293 0.1262 1
Trichomonas vaginalis glutathione reductase, putative 0.0086 0.0289 0.0465
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0332 0.0332
Trichomonas vaginalis glutaminase, putative 0.1345 0.6217 1
Trichomonas vaginalis CMGC family protein kinase 0.0099 0.0352 0.0567
Mycobacterium leprae Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.0607 0.2743 0.9642
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.015 0.0589 0.0948
Plasmodium vivax DNA repair protein REV1, putative 0.003 0.0025 0.024
Echinococcus granulosus lysosomal alpha glucosidase 0.0675 0.3061 0.3061
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.0332 0.0332
Loa Loa (eye worm) hypothetical protein 0.0033 0.004 0.0064
Mycobacterium ulcerans aldehyde dehydrogenase 0.0186 0.0762 0.119
Loa Loa (eye worm) transcription factor SMAD2 0.0248 0.1053 0.1694
Schistosoma mansoni steroid hormone receptor ad4bp 0.0049 0.0116 0.0116
Trypanosoma brucei mitochondrial DNA polymerase beta 0.096 0.4404 1
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0135 0.052 0.1166
Brugia malayi jmjC domain containing protein 0.0047 0.0104 0.0168
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0135 0.052 0.1166
Echinococcus granulosus lamin 0.0029 0.0022 0.0022
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.0174 0.0705 0.0705
Echinococcus granulosus 6 phosphofructokinase 0.0228 0.0959 0.0959
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0086 0.0289 0.064
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0093 0.0321 0.0321
Schistosoma mansoni alpha-glucosidase 0.0581 0.2619 0.2619
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.0218 0.046
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0153 0.0605 0.0936
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0089 0.0302 0.0302
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0217 0.0906 0.0906
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0049 0.0116 0.0116
Brugia malayi RNA, U transporter 1 0.0083 0.0274 0.044
Schistosoma mansoni eyes absent homolog 0.0095 0.0332 0.0332
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0049 0.0116 0.0116
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.0174 0.0705 0.0705
Loa Loa (eye worm) hypothetical protein 0.0029 0.002 0.0033
Giardia lamblia Kinase, CMGC CDK 0.0099 0.0352 0.2506
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0182 0.0743 0.1195
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0062 0.01
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0051 0.0125 0.0125
Echinococcus multilocularis lysosomal alpha glucosidase 0.0675 0.3061 0.3061
Echinococcus multilocularis lamin 0.0029 0.0022 0.0022
Schistosoma mansoni hypothetical protein 0.0091 0.0311 0.0311
Toxoplasma gondii peptidylprolyl isomerase 0.0034 0.0042 0.0336
Onchocerca volvulus Protein ultraspiracle homolog 0.0049 0.0116 0.026
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0217 0.0906 0.0906
Toxoplasma gondii ImpB/MucB/SamB family protein 0.003 0.0025 0.02
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0049 0.0116 0.0116
Brugia malayi jmjC domain containing protein 0.0047 0.0104 0.0168
Echinococcus multilocularis PHD finger protein rhinoceros 0.0093 0.0321 0.0321
Trichomonas vaginalis helicase, putative 0.0033 0.0038 0.0062
Loa Loa (eye worm) bromodomain containing protein 0.0062 0.0175 0.0282
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0089 0.0302 0.0302
Loa Loa (eye worm) hypothetical protein 0.0176 0.0712 0.1145
Loa Loa (eye worm) runx1 0.006 0.0165 0.0265
Onchocerca volvulus Bile acid receptor homolog 0.0049 0.0116 0.026
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0454 0.2024 0.4575
Loa Loa (eye worm) mbt repeat family protein 0.0051 0.0125 0.0201
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0062 0.0175 0.0281
Giardia lamblia Kinase, CMGC CDK 0.0099 0.0352 0.2506
Entamoeba histolytica recQ family helicase, putative 0.006 0.0168 0.1233
Echinococcus multilocularis FTZ F1 alpha 0.0049 0.0116 0.0116
Plasmodium falciparum phd finger protein, putative 0.0093 0.0321 0.3052
Schistosoma mansoni coup transcription factor 0.0049 0.0116 0.0116
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0628 0.2843 0.9391
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0049 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0051 0.0122 0.0197
Treponema pallidum fructose-bisphosphate aldolase 0.0313 0.1359 1
Echinococcus multilocularis lysine specific demethylase 6a 0.0047 0.0104 0.0104
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.031 0.1345 0.2163
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.003 0.0027 0.0026
Schistosoma mansoni alkaline phosphatase 0.0174 0.0705 0.0705
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0086 0.0289 0.0289
Onchocerca volvulus 0.0264 0.1129 0.2525
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0099 0.0352 0.0352
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0086 0.0289 0.0426
Trypanosoma brucei DNA polymerase kappa, putative 0.0125 0.0472 0.1039
Echinococcus multilocularis roundabout 2 0.0033 0.004 0.004
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0201 0.0833 0.0833
Plasmodium vivax SET domain protein, putative 0.0126 0.0475 0.4523
Mycobacterium tuberculosis Probable reductase 0.0565 0.2546 0.8388
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0228 0.0959 0.704
Onchocerca volvulus Serine\/threonine kinase homolog 0.0201 0.0833 0.1863
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0097 0.034 0.2695
Echinococcus multilocularis cyclin dependent kinase 5 0.0099 0.0352 0.0352
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0313 0.1359 1
Trypanosoma brucei trypanothione reductase 0.0248 0.1051 0.2359
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0361 0.0581
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0021 0.0021
Plasmodium falciparum JmjC domain-containing protein, putative 0.0047 0.0104 0.0994
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0086 0.0289 0.064
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0034 0.0042 0.0312
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0026 0.0007 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.028 0.045
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0833 0.134
Entamoeba histolytica hypothetical protein 0.0032 0.0034 0.025
Trypanosoma brucei hypothetical protein, conserved 0.003 0.0025 0.0021
Loa Loa (eye worm) glutathione reductase 0.0248 0.1051 0.1691
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0049 0.0116 0.0116
Entamoeba histolytica Flap nuclease, putative 0.0028 0.0016 0.0117
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0051 0.0126 0.0126
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.1359 0.2186
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0051 0.0125 0.028
Trichomonas vaginalis set domain proteins, putative 0.0974 0.447 0.719
Trypanosoma cruzi hypothetical protein, conserved 0.0208 0.0861 0.1942
Loa Loa (eye worm) hypothetical protein 0.0026 0.0008 0.0012
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0027 0.0215
Trypanosoma brucei cdc2-related kinase 1 0.0099 0.0352 0.0767
Trichomonas vaginalis alpha-glucosidase, putative 0.0056 0.0147 0.0237
Schistosoma mansoni protein phosphatase 2C 0.0047 0.0104 0.0104
Echinococcus multilocularis neutral alpha glucosidase AB 0.015 0.0589 0.0589
Brugia malayi Protein kinase domain containing protein 0.0099 0.0352 0.0567
Echinococcus granulosus cyclin dependent kinase 5 0.0099 0.0352 0.0352
Brugia malayi Bromodomain containing protein 0.0107 0.039 0.0628
Entamoeba histolytica cell division protein kinase 2, putative 0.0099 0.0352 0.2594
Schistosoma mansoni hypothetical protein 0.0051 0.0123 0.0123
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0074 0.0234 0.1807
Loa Loa (eye worm) hypothetical protein 0.0051 0.0122 0.0197
Echinococcus granulosus lysine specific demethylase 5A 0.0189 0.0776 0.0776
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0062 0.006
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0099 0.0352 0.0567
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0312 0.1351 0.1351
Schistosoma mansoni phd/f-box containing protein 0.0047 0.0104 0.0104
Toxoplasma gondii histone lysine-specific demethylase 0.0051 0.0122 0.0969
Leishmania major glycosyl hydrolase-like protein 0.0056 0.0147 0.0299
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0191 0.0307
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0361 0.0581
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0049 0.0116 0.0116
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0037 0.0059 0.0464
Echinococcus granulosus tar DNA binding protein 0.0065 0.0191 0.0191
Trypanosoma brucei DNA polymerase kappa, putative 0.0125 0.0472 0.1039
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0062 0.01
Trypanosoma brucei phosphoglycerate kinase 0.0182 0.0743 0.1657
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0034 0.0042 0.006
Schistosoma mansoni microtubule-associated protein tau 0.2149 1 1
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0062 0.0125
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0042 0.0083 0.0133
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0051 0.0122 0.1163
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0159 0.0327
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0178 0.0722 0.0722
Echinococcus granulosus cyclin dependent kinase 1 0.0099 0.0352 0.0352
Giardia lamblia Sgs1 DNA helicase, putative 0.0051 0.0126 0.0819
Entamoeba histolytica phosphofructokinase, putative 0.0228 0.0959 0.7056
Echinococcus multilocularis intestinal type alkaline phosphatase 0.0174 0.0705 0.0705
Loa Loa (eye worm) hypothetical protein 0.0058 0.0158 0.0255
Trichomonas vaginalis phosphofructokinase, putative 0.0228 0.0959 0.1543
Toxoplasma gondii NADPH-glutathione reductase 0.0086 0.0289 0.2288
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0062 0.0175 0.1663
Trypanosoma cruzi UDP-galactopyranose mutase 0.0051 0.0122 0.0261
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0667 0.3023 1
Trichomonas vaginalis rotamase, putative 0.0034 0.0046 0.0074
Leishmania major phosphoglycerate kinase B, cytosolic 0.0182 0.0743 0.1657
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0046 0.0074
Loa Loa (eye worm) hypothetical protein 0.0049 0.0116 0.0187
Plasmodium vivax protein kinase Crk2 0.0099 0.0352 0.3353
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0049 0.0116 0.0116
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0071 0.0218 0.035
Loa Loa (eye worm) hypothetical protein 0.0038 0.0062 0.01
Trypanosoma brucei DNA polymerase eta, putative 0.0124 0.0466 0.1027
Onchocerca volvulus Tyrosine kinase homolog 0.0317 0.1374 0.3075
Loa Loa (eye worm) heterochromatin protein 1 0.015 0.059 0.0949
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0074 0.0234 0.1858
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0153 0.0605 0.1832
Echinococcus granulosus dna polymerase eta 0.0124 0.0466 0.0466
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0049 0.0116 0.0187
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0032 0.0034 0.0034
Brugia malayi Glycosyl hydrolases family 31 protein 0.015 0.0589 0.0948
Loa Loa (eye worm) hypothetical protein 0.0028 0.0015 0.0024
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0051 0.0122 0.1163
Plasmodium vivax JmjC domain containing protein 0.0047 0.0104 0.0994
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0165 0.0659 0.1482
Echinococcus granulosus L aminoadipate semialdehyde 0.0264 0.1129 0.1129
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0313 0.1359 1
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0565 0.2546 0.8932
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0056 0.0147 0.0329
Echinococcus granulosus geminin 0.0364 0.16 0.16
Echinococcus granulosus histone acetyltransferase KAT2B 0.0296 0.1277 0.1277
Entamoeba histolytica protein kinase domain containing protein 0.0217 0.0906 0.6668
Plasmodium falciparum DNA repair protein REV1, putative 0.003 0.0025 0.024
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0182 0.0743 0.1673
Plasmodium falciparum phosphoglycerate kinase 0.0182 0.0743 0.707
Echinococcus multilocularis cyclin dependent kinase 1 0.0099 0.0352 0.0352
Brugia malayi mbt repeat family protein 0.0051 0.0125 0.0201
Brugia malayi 6-phosphofructokinase 0.0228 0.0959 0.1543
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0241 0.102 0.3236
Echinococcus granulosus cpg binding protein 0.0158 0.063 0.063
Brugia malayi AF-10 protein 0.003 0.0027 0.0044
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0051 0.0126 0.0203
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0248 0.1051 0.334
Giardia lamblia DNA damage repair protein 0.003 0.0025 0.0069
Trypanosoma brucei ISWI complex protein 0.0047 0.0106 0.0205
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0089 0.0302 0.0302
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.0607 0.2743 0.9055
Onchocerca volvulus 0.0974 0.447 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0057 0.0154 0.0248
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0049 0.0116 0.0187
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0039 0.0066 0.0066
Trypanosoma brucei DNA polymerase kappa, putative 0.0125 0.0472 0.1039
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0182 0.0743 0.2028
Brugia malayi Bromodomain containing protein 0.0125 0.0473 0.0761
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0182 0.0743 0.1195
Echinococcus granulosus protein kinase shaggy 0.0217 0.0906 0.0906
Plasmodium vivax 6-phosphofructokinase, putative 0.0062 0.0175 0.1663
Trypanosoma brucei hypothetical protein, conserved 0.003 0.0025 0.0021
Loa Loa (eye worm) hypothetical protein 0.0058 0.0159 0.0256
Trichomonas vaginalis CMGC family protein kinase 0.0099 0.0352 0.0567
Schistosoma mansoni glutaminase 0.1345 0.6217 0.6217
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0051 0.0122 0.0122
Trypanosoma cruzi trypanothione reductase, putative 0.0086 0.0289 0.064
Echinococcus multilocularis geminin 0.0364 0.16 0.16
Trichomonas vaginalis alpha-glucosidase, putative 0.015 0.0589 0.0948
Loa Loa (eye worm) hypothetical protein 0.0121 0.0454 0.073
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.1359 0.2186
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0062 0.0175 0.1237
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.006 0.0168 0.0346
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.0332 0.0332
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0071 0.0217 0.0217
Mycobacterium tuberculosis Probable oxidoreductase 0.0628 0.2843 0.9391
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.006 0.0165 0.0165
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0099 0.0352 0.0567
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.023 0.0489
Onchocerca volvulus 0.0038 0.0062 0.0139
Leishmania major phosphopantetheinyl transferase-like protein 0.0074 0.0234 0.0498
Echinococcus granulosus PHD finger protein rhinoceros 0.0093 0.0321 0.0321
Trichomonas vaginalis CMGC family protein kinase 0.0217 0.0906 0.1458
Onchocerca volvulus 0.0038 0.0062 0.0139
Echinococcus multilocularis alkaline phosphatase 0.0174 0.0705 0.0705
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.011 0.0404 0.0404
Echinococcus granulosus neuroglian 0.0026 0.0008 0.0008
Plasmodium falciparum thioredoxin reductase 0.0086 0.0289 0.2748
Trichomonas vaginalis chromobox protein, putative 0.015 0.059 0.0949
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0062 0.0125
Treponema pallidum phosphoglycerate kinase 0.0182 0.0743 0.5443
Loa Loa (eye worm) hypothetical protein 0.0029 0.0021 0.0034
Schistosoma mansoni zinc finger protein 0.0047 0.0106 0.0106
Schistosoma mansoni kinase 0.0104 0.0374 0.0374
Leishmania major hypothetical protein, conserved 0.0208 0.0861 0.1927
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0217 0.0906 0.2044
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0074 0.0234 0.1679
Trichomonas vaginalis sucrase-isomaltase, putative 0.015 0.0589 0.0948
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0038 0.0062
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0086 0.0289 0.2748
Toxoplasma gondii thioredoxin reductase 0.0248 0.1051 0.8329
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0049 0.0116 0.0116
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0089 0.0302 0.0302
Leishmania major hypothetical protein, conserved 0.0038 0.0062 0.0106
Entamoeba histolytica phosphoglycerate kinase, putative 0.0182 0.0743 0.5468
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0086 0.0289 0.0426
Mycobacterium ulcerans monoamine oxidase 0.0051 0.0122 0.0157
Mycobacterium ulcerans bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 0.0607 0.2743 0.439
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0062 0.0175 0.0846
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0182 0.0743 0.5889
Schistosoma mansoni flap endonuclease-1 0.0025 0.0003 0.0003
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0833 0.134
Trichomonas vaginalis phosphofructokinase, putative 0.0228 0.0959 0.1543
Echinococcus granulosus arachidonate 5 lipoxygenase 0.006 0.0165 0.0165
Echinococcus granulosus bloom syndrome protein 0.0094 0.0327 0.0327
Echinococcus multilocularis musashi 0.0029 0.0022 0.0022
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0057 0.0154 0.0248
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0049 0.0116 0.0187
Loa Loa (eye worm) CHromoDomain protein family member 0.0039 0.0066 0.0107
Trypanosoma cruzi cdc2-related kinase 1 0.0099 0.0352 0.0784
Plasmodium falciparum thioredoxin reductase 0.0248 0.1051 1
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0022 0.0035
Loa Loa (eye worm) hypothetical protein 0.0049 0.0116 0.0187
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0028 0.0016 0.0019
Echinococcus multilocularis chromobox protein 1 0.015 0.059 0.059
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0047 0.0104 0.022
Loa Loa (eye worm) hypothetical protein 0.0051 0.0122 0.0197
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0097 0.034 0.0547
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0049 0.0116 0.0187
Loa Loa (eye worm) steroid hormone receptor 0.0049 0.0116 0.0187
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0049 0.0116 0.0116
Schistosoma mansoni hypothetical protein 0.2055 0.9559 0.9559
Leishmania major hypothetical protein, conserved 0.0047 0.0104 0.0202
Loa Loa (eye worm) MH2 domain-containing protein 0.0248 0.1053 0.1694
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0057 0.0154 0.0248
Brugia malayi intracellular kinase 0.0217 0.0906 0.1458
Schistosoma mansoni serine/threonine protein kinase 0.0201 0.0833 0.0833
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0049 0.0116 0.0187
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0049 0.0116 0.0187
Loa Loa (eye worm) apoptosis regulator protein 0.0089 0.0302 0.0486
Trypanosoma brucei DNA polymerase kappa, putative 0.0125 0.0472 0.1039
Schistosoma mansoni jumonji domain containing protein 0.0304 0.1316 0.1316
Mycobacterium tuberculosis Conserved hypothetical protein 0.0506 0.2265 0.7441
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0077 0.0249 0.0249
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0086 0.0289 0.0622
Schistosoma mansoni hypothetical protein 0.003 0.0027 0.0027
Giardia lamblia Kinase, CMGC GSK 0.0217 0.0906 0.6629
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0191 0.0191
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0051 0.0126 0.0126
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0191 0.0191
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0086 0.0289 0.064
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0086 0.0289 0.0765
Trichomonas vaginalis maltase-glucoamylase, putative 0.0056 0.0147 0.0237
Brugia malayi Phosphoglycerate kinase 0.0067 0.02 0.0321
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0191 0.0191
Trypanosoma brucei DNA polymerase kappa, putative 0.0125 0.0472 0.1039
Loa Loa (eye worm) hypothetical protein 0.0089 0.0302 0.0486
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0086 0.0289 0.0622
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0051 0.0122 0.1163
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0083 0.0133
Brugia malayi Ets-domain containing protein 0.0142 0.0551 0.0886
Trichomonas vaginalis DNA polymerase eta, putative 0.0125 0.0472 0.0759
Schistosoma mansoni hypothetical protein 0.0089 0.0302 0.0302
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.004 0.0074 0.0074
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0096 0.0338 0.0338
Brugia malayi steroid hormone receptor 0.0049 0.0116 0.0187
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.0332 0.0332
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0071 0.0218 0.0218
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0264 0.1129 0.1129
Mycobacterium ulcerans molybdopterin-guanine dinucleotide biosynthesis protein A 0.0111 0.0409 0.0619
Brugia malayi photoreceptor-specific nuclear receptor 0.0049 0.0116 0.0187
Schistosoma mansoni lamin 0.0029 0.0022 0.0022
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0191 0.0191
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0833 0.134
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0165 0.0265
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0071 0.0218 0.046
Schistosoma mansoni hypothetical protein 0.0063 0.0183 0.0183
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0074 0.0234 0.1858
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.096 0.4404 1
Schistosoma mansoni hypothetical protein 0.0047 0.0106 0.0106
Trypanosoma cruzi DNA polymerase eta, putative 0.0124 0.0466 0.1044
Echinococcus multilocularis mixed lineage leukemia protein mll 0.004 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0056 0.0147 0.0237
Schistosoma mansoni phosphoglycerate kinase 0.0182 0.0743 0.0743
Schistosoma mansoni bromodomain containing protein 0.021 0.0873 0.0873
Echinococcus granulosus fetal alzheimer antigen falz 0.0077 0.0249 0.0249
Schistosoma mansoni hypothetical protein 0.0089 0.0302 0.0302
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0049 0.0116 0.0187
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.0042 0.0079
Plasmodium vivax hypothetical protein, conserved 0.0051 0.0122 0.1163
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0062 0.0062
Brugia malayi hypothetical protein 0.0026 0.0007 0.0011
Loa Loa (eye worm) hypothetical protein 0.0095 0.0332 0.0534
Giardia lamblia NADH oxidase lateral transfer candidate 0.0086 0.0289 0.2032
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0086 0.0289 0.2288
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.004 0.0074 0.0074
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0217 0.0906 0.7181
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0049 0.0116 0.0187
Brugia malayi beta-lactamase family protein 0.0038 0.0062 0.01
Plasmodium vivax 6-phosphofructokinase, putative 0.0062 0.0175 0.1663
Entamoeba histolytica acetyltransferase, GNAT family 0.0082 0.0271 0.1992
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0034 0.0046 0.0074
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0058 0.0158 0.0158
Schistosoma mansoni DNA helicase recq1 0.0051 0.0126 0.0126
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0049 0.0116 0.0116
Loa Loa (eye worm) jmjC domain-containing protein 0.0047 0.0104 0.0168
Trypanosoma brucei DNA damage repair protein, putative 0.003 0.0025 0.0021
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0039 0.0066 0.0066
Toxoplasma gondii PHD-finger domain-containing protein 0.0093 0.0321 0.2542
Mycobacterium ulcerans hypothetical protein 0.0111 0.0409 0.0619
Schistosoma mansoni blooms syndrome DNA helicase 0.0026 0.0008 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0025 0.004
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0056 0.0147 0.0317
Toxoplasma gondii hypothetical protein 0.0155 0.0614 0.4861
Brugia malayi Ets-domain containing protein 0.0142 0.0551 0.0886
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.0174 0.0705 0.0705
Loa Loa (eye worm) hypothetical protein 0.0096 0.0335 0.0539
Entamoeba histolytica hypothetical protein 0.0032 0.0034 0.025
Echinococcus multilocularis cpg binding protein 0.0158 0.063 0.063
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0201 0.0833 0.134
Trichomonas vaginalis CMGC family protein kinase 0.0099 0.0352 0.0567
Echinococcus multilocularis peregrin 0.0107 0.039 0.039
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0086 0.0289 0.0622
Entamoeba histolytica protein kinase, putative 0.0217 0.0906 0.6668
Schistosoma mansoni DNA polymerase IV / kappa 0.003 0.0025 0.0025
Schistosoma mansoni zinc finger protein 0.0076 0.0241 0.0241
Loa Loa (eye worm) hypothetical protein 0.0047 0.0104 0.0168
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0217 0.0906 0.2029
Giardia lamblia PHD finger protein 15 0.0093 0.0321 0.227
Brugia malayi 6-phosphofructokinase 0.0228 0.0959 0.1543
Entamoeba histolytica phosphofructokinase, putative 0.0228 0.0959 0.7056
Loa Loa (eye worm) hypothetical protein 0.0051 0.0122 0.0197
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0047 0.0104 0.0202
Trichomonas vaginalis chromobox protein, putative 0.009 0.031 0.0499
Schistosoma mansoni sex comb on midleg homolog 0.0051 0.0125 0.0125
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0049 0.0116 0.0116
Trypanosoma brucei DNA polymerase kappa, putative 0.0125 0.0472 0.1039
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0049 0.0116 0.0116
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0067 0.02 0.0437
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0565 0.2546 0.8388
Brugia malayi glutathione reductase 0.0248 0.1051 0.1691
Echinococcus granulosus snurportin 1 0.031 0.1345 0.1345
Loa Loa (eye worm) hypothetical protein 0.0095 0.0332 0.0534
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0228 0.0959 0.3029
Echinococcus granulosus histone lysine methyltransferase setb 0.0178 0.0722 0.0722
Echinococcus multilocularis ecdysone induced protein 78C 0.0049 0.0116 0.0116
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0038 0.0062
Echinococcus multilocularis cyclin dependent kinase 0.0099 0.0352 0.0352
Echinococcus granulosus jumonji domain containing 1A 0.0047 0.0104 0.0104
Mycobacterium tuberculosis Conserved hypothetical protein 0.0111 0.0409 0.117
Trypanosoma cruzi DNA polymerase kappa, putative 0.0125 0.0472 0.1056
Schistosoma mansoni lipoxygenase 0.006 0.0165 0.0165
Trichomonas vaginalis phosphofructokinase, putative 0.0062 0.0175 0.0281
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0191 0.0307
Onchocerca volvulus Heterochromatin protein 1 homolog 0.009 0.031 0.0694
Schistosoma mansoni alpha glucosidase 0.015 0.0589 0.0589
Giardia lamblia Kinase, CMGC GSK 0.0217 0.0906 0.6629
Schistosoma mansoni nuclear hormone receptor 0.0049 0.0116 0.0116
Brugia malayi phosphofructokinase 0.0228 0.0959 0.1543
Echinococcus multilocularis 0.0051 0.0122 0.0122
Trypanosoma brucei phosphoglycerate kinase, putative 0.0067 0.02 0.0419
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0028 0.0016 0.0126
Echinococcus granulosus chromobox protein 1 0.015 0.059 0.059
Loa Loa (eye worm) RecQ helicase 0.0094 0.0327 0.0526
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0049 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0038 0.0062 0.01
Loa Loa (eye worm) hypothetical protein 0.0049 0.0116 0.0187
Loa Loa (eye worm) phosphofructokinase 0.0228 0.0959 0.1543
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0833 0.134
Trichomonas vaginalis chromobox protein, putative 0.009 0.031 0.0499
Mycobacterium ulcerans hypothetical protein 0.0038 0.0062 0.006
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0099 0.0352 0.0767
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0062 0.0062
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0084 0.028 0.0626
Echinococcus multilocularis zinc finger protein 0.0076 0.0241 0.0241
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0096 0.0338 0.0544
Loa Loa (eye worm) hypothetical protein 0.0248 0.1052 0.1693
Trichomonas vaginalis alpha-glucosidase, putative 0.015 0.0589 0.0948
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0067 0.02 0.0419
Trichomonas vaginalis bromodomain-containing protein, putative 0.0097 0.034 0.0547
Echinococcus multilocularis dna polymerase eta 0.0124 0.0466 0.0466
Mycobacterium ulcerans phosphoglycerate kinase 0.0182 0.0743 0.1159
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.1359 0.2186
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0051 0.0122 0.0122
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0565 0.2546 0.8388
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.0234 0.0498
Echinococcus granulosus twitchin 0.003 0.0025 0.0025
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0051 0.0126 0.0203
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0022 0.0035
Plasmodium falciparum protoporphyrinogen oxidase 0.0051 0.0122 0.1163
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0038 0.0062
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.1359 0.2186
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0051 0.0122 0.0122
Leishmania major DNA polymerase kappa, putative 0.003 0.0025 0.0021
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0217 0.0906 0.1458
Loa Loa (eye worm) histone methyltransferase 0.0049 0.0116 0.0186
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0118 0.0439 0.0439
Brugia malayi Flap endonuclease-1 0.0028 0.0016 0.0026
Loa Loa (eye worm) hypothetical protein 0.0093 0.0321 0.0516
Loa Loa (eye worm) RNA binding protein 0.0065 0.0191 0.0307
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0086 0.0289 0.0217
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0062 0.0106
Brugia malayi F/Y-rich N-terminus family protein 0.0085 0.0283 0.0456
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0026 0.0007 0.0007
Brugia malayi Thioredoxin reductase 0.0248 0.1051 0.1691
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0565 0.2546 0.8388
Brugia malayi PHD-finger family protein 0.0092 0.0318 0.0512
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0339 0.148 0.238
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0051 0.0126 0.1198
Trypanosoma brucei unspecified product 0.0066 0.0197 0.0413
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0454 0.2024 0.4585
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0086 0.0289 0.0465
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0049 0.0116 0.0187
Brugia malayi beta-lactamase 0.0038 0.0062 0.01
Trichomonas vaginalis mercuric reductase, putative 0.0086 0.0289 0.0465
Loa Loa (eye worm) hypothetical protein 0.0051 0.0122 0.0197
Brugia malayi chromobox protein homolog 3 0.0084 0.028 0.045
Brugia malayi jmjC domain containing protein 0.0367 0.161 0.259
Echinococcus multilocularis 6 phosphofructokinase 0.0228 0.0959 0.0959
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0062 0.0175 0.1183
Mycobacterium ulcerans oxidoreductase 0.0051 0.0122 0.0157
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0086 0.0289 0.064
Loa Loa (eye worm) glutaminase 2 0.1345 0.6217 1
Echinococcus multilocularis phosphoglycerate kinase 1 0.0182 0.0743 0.0743
Plasmodium falciparum histone acetyltransferase GCN5 0.0082 0.0271 0.2576
Echinococcus granulosus peregrin 0.0107 0.039 0.039
Schistosoma mansoni jumonji domain containing protein 0.0047 0.0104 0.0104
Echinococcus granulosus JmjC domain containing protein 4 0.0047 0.0104 0.0104
Echinococcus multilocularis JmjC domain containing protein 4 0.0047 0.0104 0.0104
Onchocerca volvulus 0.0144 0.0564 0.1261
Loa Loa (eye worm) hypothetical protein 0.0264 0.1129 0.1816
Echinococcus granulosus SAM and MBT domain containing protein 0.0051 0.0125 0.0125
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0074 0.0234 0.0581
Giardia lamblia Fructose-bisphosphate aldolase 0.0313 0.1359 1
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0034 0.0046 0.0074
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.096 0.4404 1
Brugia malayi Nuclear hormone receptor-like 1 0.0049 0.0116 0.0187
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0182 0.0743 0.5889
Loa Loa (eye worm) hypothetical protein 0.0051 0.0126 0.0203
Trichomonas vaginalis phosphofructokinase, putative 0.0228 0.0959 0.1543
Onchocerca volvulus Alhambra homolog 0.0093 0.0321 0.0718
Loa Loa (eye worm) hypothetical protein 0.0038 0.0062 0.01
Brugia malayi Fli-1 protein 0.043 0.1907 0.3068
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0067 0.02 0.0437
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0126 0.0475 0.0475
Mycobacterium ulcerans aldehyde dehydrogenase 0.0186 0.0762 0.119
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0264 0.1129 0.1816
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0032 0.0034 0.0034
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0057 0.0154 0.1218
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0186 0.0762 0.0762
Mycobacterium ulcerans glutaminase 0.1345 0.6217 1
Echinococcus multilocularis snurportin 1 0.031 0.1345 0.1345
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0049 0.0116 0.0187
Loa Loa (eye worm) hypothetical protein 0.0475 0.2119 0.3409
Leishmania major hypothetical protein, conserved 0.0047 0.0106 0.0205
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.1359 0.2186
Brugia malayi cell division control protein 2 homolog 0.0099 0.0352 0.0567
Brugia malayi PHD-finger family protein 0.0093 0.0321 0.0516
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0051 0.0126 0.0998
Loa Loa (eye worm) hypothetical protein 0.0047 0.0104 0.0168
Schistosoma mansoni DNA helicase recq5 0.0051 0.0126 0.0126
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0049 0.0116 0.0187
Trichomonas vaginalis alpha-glucosidase, putative 0.0056 0.0147 0.0237
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0182 0.0743 0.1673
Echinococcus multilocularis flap endonuclease 1 0.0028 0.0016 0.0016
Brugia malayi nuclear hormone receptor 0.0049 0.0116 0.0187
Leishmania major mitochondrial DNA polymerase beta 0.096 0.4404 1
Leishmania major ATP-dependent phosphofructokinase 0.0228 0.0959 0.2149
Leishmania major DNA polymerase kappa, putative 0.0103 0.0371 0.081
Plasmodium falciparum glutathione reductase 0.0086 0.0289 0.2748
Schistosoma mansoni thyroid hormone receptor 0.0049 0.0116 0.0116
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0047 0.0104 0.0104
Echinococcus granulosus Chromobox protein 3 0.0025 0.000000024027 0.000000024027
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0086 0.0289 0.064
Echinococcus multilocularis thioredoxin glutathione reductase 0.025 0.1061 0.1061
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0095 0.0332 0.0534
Schistosoma mansoni cpg binding protein 0.0158 0.063 0.063
Trichomonas vaginalis alpha-glucosidase, putative 0.0056 0.0147 0.0237
Loa Loa (eye worm) jmjC domain-containing protein 0.0189 0.0776 0.1248
Echinococcus granulosus transcription factor Dp 1 0.0041 0.0077 0.0077
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0856 0.3915 0.6298
Echinococcus multilocularis bloom syndrome protein 0.0094 0.0327 0.0327
Trypanosoma cruzi hypothetical protein, conserved 0.015 0.0589 0.1323
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0057 0.0154 0.0248
Schistosoma mansoni alpha-glucosidase 0.0581 0.2619 0.2619
Trypanosoma cruzi polo-like protein kinase, putative 0.0201 0.0833 0.1877
Plasmodium vivax thioredoxin reductase, putative 0.0248 0.1051 1
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0051 0.0122 0.1163
Trypanosoma cruzi ISWI complex protein 0.0047 0.0106 0.0223
Mycobacterium tuberculosis Possible oxidoreductase 0.0051 0.0122 0.0203
Echinococcus multilocularis dnaJ subfamily B 0.2055 0.9559 0.9559
Schistosoma mansoni blooms syndrome DNA helicase 0.0068 0.0204 0.0204
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0074 0.0234 0.2231
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0097 0.034 0.3235
Loa Loa (eye worm) hypothetical protein 0.0133 0.0509 0.0818
Brugia malayi jmjC domain containing protein 0.0047 0.0104 0.0168
Echinococcus granulosus histone acetyltransferase MYST2 0.0058 0.0158 0.0158
Echinococcus multilocularis GA binding protein alpha chain 0.0142 0.0551 0.0551
Schistosoma mansoni hypothetical protein 0.031 0.1345 0.1345
Trichomonas vaginalis alpha-glucosidase, putative 0.0056 0.0147 0.0237
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0367 0.161 0.161
Brugia malayi serine/threonine-protein kinase plk-2 0.0201 0.0833 0.134
Brugia malayi nuclear receptor NHR-88 0.0049 0.0116 0.0187
Schistosoma mansoni gabp alpha 0.0142 0.0551 0.0551
Brugia malayi hypothetical protein 0.0095 0.0332 0.0534
Loa Loa (eye worm) hypothetical protein 0.0217 0.0907 0.1459
Schistosoma mansoni thyroid hormone receptor 0.0049 0.0116 0.0116
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0062 0.01
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0311 0.1347 0.1347
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.006 0.0167 0.159
Mycobacterium ulcerans beta-lactamase 0.0038 0.0062 0.006
Trichomonas vaginalis rotamase, putative 0.0034 0.0042 0.0068
Trypanosoma cruzi DNA polymerase eta, putative 0.0057 0.0154 0.0332
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0062 0.0062
Brugia malayi CHD4 protein 0.0039 0.0066 0.0107
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0628 0.2843 0.9391
Trypanosoma cruzi cdc2-related kinase 1 0.0099 0.0352 0.0784
Schistosoma mansoni nephrin 0.0026 0.0008 0.0008
Loa Loa (eye worm) beta-lactamase 0.0038 0.0062 0.01
Brugia malayi Bromodomain containing protein 0.0246 0.1043 0.1677
Schistosoma mansoni jumonji/arid domain-containing protein 0.0189 0.0776 0.0776
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0099 0.0352 0.2793
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0051 0.0122 0.0216
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0039 0.0066 0.0066
Echinococcus multilocularis thyroid hormone receptor alpha 0.0049 0.0116 0.0116
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0021 0.0012
Brugia malayi PHD-finger family protein 0.0044 0.0093 0.015
Brugia malayi jmjC domain containing protein 0.0189 0.0776 0.1248
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0228 0.0959 0.2164
Mycobacterium ulcerans hypothetical protein 0.0111 0.0409 0.0619
Loa Loa (eye worm) flap endonuclease-1 0.0028 0.0016 0.0026
Mycobacterium ulcerans DNA polymerase IV 0.0125 0.0472 0.0722
Trypanosoma brucei DNA polymerase kappa, putative 0.0103 0.0371 0.081
Trichomonas vaginalis flap endonuclease-1, putative 0.0028 0.0016 0.0026
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0086 0.0289 0.064
Trypanosoma brucei phosphoglycerate kinase 0.0182 0.0743 0.1657
Loa Loa (eye worm) thioredoxin reductase 0.0248 0.1051 0.1691
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0833 0.134
Brugia malayi SWIRM domain containing protein 0.0051 0.0122 0.0197
Echinococcus granulosus importin subunit beta 1 0.0029 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0038 0.0062 0.01
Trichomonas vaginalis alpha-glucosidase, putative 0.015 0.0589 0.0948
Loa Loa (eye worm) fli-1 protein 0.043 0.1907 0.3068
Echinococcus multilocularis phd:f box containing protein 0.0047 0.0104 0.0104
Trypanosoma cruzi UDP-galactopyranose mutase 0.0051 0.0122 0.0261
Plasmodium falciparum importin beta, putative 0.0029 0.0021 0.0203
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0096 0.0338 0.0338
Plasmodium falciparum protein kinase 5 0.0099 0.0352 0.3353
Echinococcus granulosus lysine specific demethylase 6a 0.0047 0.0104 0.0104
Echinococcus multilocularis SAM and MBT domain containing protein 0.0051 0.0125 0.0125
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0085 0.0286 0.2717
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0135 0.052 0.1166
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0049 0.0116 0.0187
Trichomonas vaginalis DNA helicase recq, putative 0.006 0.0168 0.027
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0011
Echinococcus granulosus dnaJ subfamily B 0.2055 0.9559 0.9559
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0159 0.0327
Trypanosoma brucei unspecified product 0.0118 0.0439 0.0964
Onchocerca volvulus 0.0051 0.0125 0.028
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0089 0.0302 0.0486
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.015 0.0591 0.0591
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0074 0.0234 0.2231
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0047 0.0104 0.022
Echinococcus multilocularis chromobox protein 1 0.015 0.059 0.059
Echinococcus multilocularis histone acetyltransferase MYST2 0.0058 0.0158 0.0158
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0056 0.0147 0.0237
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.0007 0.0011
Echinococcus granulosus FTZ F1 alpha 0.0049 0.0116 0.0116
Onchocerca volvulus 0.015 0.0591 0.1322
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.006 0.0168 0.0364
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0062 0.01
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0011
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0062 0.0062
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0089 0.0302 0.0302
Entamoeba histolytica serine/threonine protein kinase, putative 0.0201 0.0833 0.6128
Loa Loa (eye worm) MBCTL1 0.0058 0.0158 0.0255
Onchocerca volvulus 0.0051 0.0123 0.0275
Echinococcus granulosus intermediate filament protein 0.0029 0.0022 0.0022
Echinococcus granulosus chromobox protein 1 0.015 0.059 0.059
Mycobacterium tuberculosis Conserved hypothetical protein 0.0051 0.0122 0.0203
Plasmodium vivax glutathione reductase, putative 0.0248 0.1051 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0116 0.0187
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0038 0.0062
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.003 0.0027 0.0215
Echinococcus multilocularis dna polymerase kappa 0.0125 0.0472 0.0472
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0051 0.0126 0.0126
Mycobacterium tuberculosis Conserved hypothetical protein 0.0096 0.0338 0.0931
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0086 0.0289 0.0622
Schistosoma mansoni terminal deoxycytidyl transferase 0.0096 0.0338 0.0338
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.023 0.0489
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.0174 0.0705 0.0705
Loa Loa (eye worm) hypothetical protein 0.0124 0.0466 0.075
Trypanosoma brucei protein kinase, putative 0.0217 0.0906 0.2029
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.0332 0.0332
Toxoplasma gondii eukaryotic initiation factor-2B, gamma subunit, putative 0.0111 0.0409 0.3239
Loa Loa (eye worm) hypothetical protein 0.0066 0.0195 0.0313
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0026 0.0008 0.006
Echinococcus multilocularis lamin dm0 0.0029 0.0022 0.0022
Onchocerca volvulus 0.0475 0.2119 0.4741
Loa Loa (eye worm) hypothetical protein 0.0029 0.0022 0.0035
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0675 0.3061 0.4924
Schistosoma mansoni rotamase 0.0034 0.0046 0.0046
Plasmodium falciparum glycogen synthase kinase 3 0.0217 0.0906 0.8622
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0011
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0086 0.0289 0.0289
Trichomonas vaginalis chromobox protein, putative 0.015 0.059 0.0949
Echinococcus multilocularis microtubule associated protein 2 0.2149 1 1
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0028 0.0015 0.0015
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0062 0.0175 0.1385
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0096 0.0338 0.0338
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0056 0.0147 0.1082
Onchocerca volvulus 0.0217 0.0906 0.2027
Trypanosoma brucei DNA polymerase kappa, putative 0.0073 0.023 0.0489
Loa Loa (eye worm) hypothetical protein 0.0182 0.0743 0.1195
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0039 0.0069 0.0652
Loa Loa (eye worm) 6-phosphofructokinase 0.0228 0.0959 0.1543
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0057 0.0154 0.0248
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0086 0.0289 0.0622
Trypanosoma cruzi DNA polymerase kappa, putative 0.0125 0.0472 0.1056
Loa Loa (eye worm) jmjC domain-containing protein 0.0047 0.0104 0.0168
Brugia malayi Pre-SET motif family protein 0.0856 0.3915 0.6298
Schistosoma mansoni methyl-cpg binding protein mbd 0.0052 0.0131 0.0131
Trypanosoma brucei unspecified product 0.0066 0.0197 0.0413
Trypanosoma brucei glycosyl hydrolase-like protein 0.0056 0.0147 0.0299
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0228 0.0959 0.2149
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.003 0.0027 0.0026
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0049 0.0116 0.0116
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0086 0.0289 0.0622
Trypanosoma cruzi DNA polymerase kappa, putative 0.0125 0.0472 0.1056
Trypanosoma cruzi ISWI complex protein 0.0047 0.0106 0.0223
Echinococcus granulosus expressed protein 0.0034 0.0046 0.0046
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0049 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0049 0.0116 0.0187
Echinococcus multilocularis survival motor neuron protein 1 0.0248 0.1052 0.1052
Schistosoma mansoni hypothetical protein 0.0089 0.0302 0.0302
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0011
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0086 0.0289 0.2748
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0186 0.0762 0.0762
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0074 0.0234 0.0338
Trypanosoma cruzi DNA damage repair protein, putative 0.003 0.0025 0.004
Loa Loa (eye worm) hypothetical protein 0.0049 0.0116 0.0187
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0565 0.2546 0.8388
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0833 0.134
Plasmodium vivax hypothetical protein, conserved 0.0051 0.0122 0.1163
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.006 0.0168 0.0346
Echinococcus granulosus thioredoxin glutathione reductase 0.025 0.1061 0.1061
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0062 0.01
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0067 0.02 0.0437
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0153 0.0605 0.1951
Leishmania major phosphoglycerate kinase C, glycosomal 0.0182 0.0743 0.1657
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0056 0.0147 0.0317
Trichomonas vaginalis alpha-glucosidase, putative 0.0056 0.0147 0.0237
Echinococcus granulosus lamin dm0 0.0029 0.0022 0.0022
Brugia malayi Importin beta-1 subunit 0.0029 0.0021 0.0034
Mycobacterium tuberculosis Conserved hypothetical protein 0.0111 0.0409 0.117
Treponema pallidum NADH oxidase 0.0086 0.0289 0.2081
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0095 0.0332 0.0534
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0062 0.0175 0.1663
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0062 0.01
Brugia malayi glutaminase DH11.1 0.1345 0.6217 1
Plasmodium vivax phosphoglycerate kinase, putative 0.0182 0.0743 0.707
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0228 0.0959 0.3225
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0049 0.0116 0.0116
Giardia lamblia DINP protein human, muc B family 0.0103 0.0371 0.2645
Schistosoma mansoni hypothetical protein 0.0364 0.16 0.16
Trichomonas vaginalis phosphofructokinase, putative 0.0228 0.0959 0.1543
Trichomonas vaginalis phosphofructokinase, putative 0.0062 0.0175 0.0281
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0165 0.0265
Trichomonas vaginalis alpha-glucosidase, putative 0.015 0.0589 0.0948
Echinococcus granulosus survival motor neuron protein 1 0.0248 0.1052 0.1052
Onchocerca volvulus 0.0049 0.0116 0.026
Schistosoma mansoni survival motor neuron protein 0.0051 0.0123 0.0123
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0206 0.0852 0.0852
Giardia lamblia Kinase, PLK 0.0201 0.0833 0.6082
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0217 0.0906 0.1458
Trypanosoma brucei DNA polymerase kappa, putative 0.0125 0.0472 0.1039
Trichomonas vaginalis phosphofructokinase, putative 0.0062 0.0175 0.0281
Mycobacterium ulcerans lipase LipD 0.0038 0.0062 0.006
Brugia malayi CXXC zinc finger family protein 0.0144 0.0564 0.0907
Trypanosoma brucei DNA polymerase IV, putative 0.0125 0.0472 0.1039
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0191 0.0191
Loa Loa (eye worm) hypothetical protein 0.0051 0.0125 0.0201
Loa Loa (eye worm) hypothetical protein 0.0038 0.0062 0.01
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0077 0.0249 0.0249
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0049 0.0116 0.0187
Leishmania major UDP-galactopyranose mutase 0.0051 0.0122 0.0242
Echinococcus multilocularis transcription factor Dp 1 0.0041 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0033 0.004 0.0064
Loa Loa (eye worm) hypothetical protein 0.0475 0.2119 0.3409
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0103 0.0371 0.1043
Toxoplasma gondii PHD-finger domain-containing protein 0.0093 0.0321 0.2542
Schistosoma mansoni serine/threonine protein kinase 0.0099 0.0352 0.0352
Schistosoma mansoni amine oxidase 0.0051 0.0122 0.0122
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0178 0.0722 0.0722
Loa Loa (eye worm) hypothetical protein 0.0049 0.0116 0.0187
Onchocerca volvulus 0.0029 0.0022 0.0048
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0021 0.0169
Trichomonas vaginalis phosphofructokinase, putative 0.0062 0.0175 0.0281
Giardia lamblia Phosphoglycerate kinase 0.0182 0.0743 0.5415
Echinococcus granulosus alkaline phosphatase 0.0174 0.0705 0.0705
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.011 0.0404 0.0404
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1709 0.7929 0.7929
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0058 0.0158 0.0255
Trichomonas vaginalis phosphofructokinase, putative 0.0062 0.0175 0.0281
Echinococcus multilocularis jumonji domain containing protein 0.0129 0.0492 0.0492
Trypanosoma cruzi cdc2-related kinase 3 0.0099 0.0352 0.0784
Trypanosoma brucei DNA polymerase IV, putative 0.0125 0.0472 0.1039
Mycobacterium ulcerans 6-phosphofructokinase 0.0228 0.0959 0.1508
Mycobacterium ulcerans dehydrogenase 0.0051 0.0122 0.0157
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0717 0.3261 0.5225
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.015 0.0589 0.4337
Onchocerca volvulus 0.0038 0.0062 0.0139
Brugia malayi jmjC domain containing protein 0.0047 0.0104 0.0168
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0049 0.0116 0.0187
Trypanosoma cruzi hypothetical protein, conserved 0.0208 0.0861 0.1942
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0332 0.0332
Schistosoma mansoni aldehyde dehydrogenase 0.0186 0.0762 0.0762
Leishmania major trypanothione reductase 0.0248 0.1051 0.2359
Trypanosoma brucei DNA damage repair protein, putative 0.003 0.0025 0.0021
Schistosoma mansoni chromobox protein 0.015 0.059 0.059
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0047 0.0104 0.0828
Echinococcus granulosus roundabout 2 0.0033 0.004 0.004
Trypanosoma cruzi trypanothione reductase, putative 0.0248 0.1051 0.2373
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0086 0.0289 0.0622
Schistosoma mansoni alkaline phosphatase 0.0174 0.0705 0.0705
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0051 0.0126 0.0998
Schistosoma mansoni methyl-cpg binding protein mbd 0.0052 0.0131 0.0131
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0049 0.0116 0.0187
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0071 0.0218 0.0218
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0125 0.0472 0.0759
Echinococcus multilocularis expressed protein 0.0034 0.0046 0.0046
Leishmania major alpha glucosidase II subunit, putative 0.015 0.0589 0.1307
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0061 0.0171 0.0171
Mycobacterium leprae conserved hypothetical protein 0.0074 0.0234 0.0619
Schistosoma mansoni chromobox protein 0.015 0.059 0.059
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0049 0.0116 0.0116
Brugia malayi ImpB/MucB/SamB family protein 0.0124 0.0466 0.075
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0025 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0049 0.0116 0.0187
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0057 0.0154 0.0248
Trypanosoma brucei chrX additional, unordered contigs 0.003 0.0025 0.0021
Loa Loa (eye worm) hypothetical protein 0.028 0.1204 0.1937
Mycobacterium tuberculosis Probable dehydrogenase 0.0565 0.2546 0.8388
Echinococcus multilocularis lysosomal alpha glucosidase 0.0675 0.3061 0.3061
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0067 0.02 0.0437
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0332 0.0332
Trypanosoma cruzi hypothetical protein, conserved 0.015 0.0589 0.1323
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0086 0.0289 0.0217
Schistosoma mansoni DNA polymerase eta 0.0124 0.0466 0.0466
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0049 0.0116 0.0187
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.015 0.0589 0.0948
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0062 0.0593
Trichomonas vaginalis DNA helicase recq1, putative 0.0094 0.0327 0.0526
Brugia malayi amine oxidase, flavin-containing family protein 0.0051 0.0122 0.0197
Brugia malayi hypothetical protein 0.0248 0.1052 0.1693
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.015 0.0589 0.4337
Leishmania major DNA polymerase eta, putative 0.0124 0.0466 0.1027
Echinococcus granulosus cyclin dependent kinase 0.0099 0.0352 0.0352
Onchocerca volvulus 0.0066 0.0195 0.0435
Brugia malayi SET domain containing protein 0.0032 0.0036 0.0058
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0049 0.0116 0.0116
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0182 0.0743 0.2449
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0063 0.0181 0.0292
Brugia malayi TAR-binding protein 0.0065 0.0191 0.0307
Treponema pallidum licC protein (licC) 0.0111 0.0409 0.2968
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0086 0.0289 0.064
Loa Loa (eye worm) CXXC zinc finger family protein 0.0144 0.0564 0.0907
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0021 0.0012
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0059 0.0164 0.1297
Plasmodium vivax hypothetical protein, conserved 0.0093 0.0321 0.3052
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0049 0.0116 0.0116
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0833 0.134
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0038 0.0062
Entamoeba histolytica protein kinase domain containing protein 0.0217 0.0906 0.6668
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0142 0.0551 0.0886
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0057 0.0154 0.0248
Toxoplasma gondii 6-phosphofructokinase 0.0062 0.0175 0.1385
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0074 0.0234 0.0338
Entamoeba histolytica recQ family DNA helicase 0.0026 0.0008 0.0056
Schistosoma mansoni sex comb on midleg homolog 0.0051 0.0125 0.0125
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.0123 0.0197
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0051 0.0122 0.0157
Brugia malayi mbt repeat family protein 0.0051 0.0125 0.0201
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0026 0.0007 0.0007
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0126 0.0475 0.0475
Brugia malayi RNA binding protein 0.0065 0.0191 0.0307
Schistosoma mansoni cpg binding protein 0.0158 0.063 0.063
Entamoeba histolytica recQ family helicase, putative 0.0025 0.0003 0.0021
Loa Loa (eye worm) hypothetical protein 0.0051 0.0122 0.0197
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0062 0.0175 0.0846
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0049 0.0116 0.0116
Wolbachia endosymbiont of Brugia malayi N-acetylglucosamine-1-phosphate uridyltransferase 0.0607 0.2743 1
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0063 0.0181 0.0292
Trypanosoma cruzi DNA polymerase kappa, putative 0.0125 0.0472 0.1056
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0071 0.0218 0.1601
Echinococcus multilocularis Protein lozenge 0.006 0.0165 0.0165
Entamoeba histolytica deoxycytidyl transferase, putative 0.0096 0.0338 0.2486
Trypanosoma brucei DNA polymerase kappa, putative 0.0125 0.0472 0.1039
Mycobacterium ulcerans DNA polymerase IV 0.0125 0.0472 0.0722
Echinococcus granulosus histone acetyltransferase KAT2B 0.0097 0.034 0.034
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0062 0.01
Schistosoma mansoni apoptosis regulator bax 0.0089 0.0302 0.0302
Echinococcus granulosus intestinal type alkaline phosphatase 0.0174 0.0705 0.0705
Trichomonas vaginalis maltase-glucoamylase, putative 0.015 0.0589 0.0948
Entamoeba histolytica cell division protein kinase 2, putative 0.0099 0.0352 0.2594
Plasmodium vivax importin-beta 2, putative 0.0029 0.0021 0.0203
Brugia malayi Steroid receptor seven-up type 2 0.0049 0.0116 0.0187
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.015 0.0589 0.4671
Onchocerca volvulus 0.0029 0.0022 0.0048
Mycobacterium ulcerans hypothetical protein 0.0506 0.2265 0.3618
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0071 0.0218 0.035
Echinococcus granulosus ecdysone induced protein 78C 0.0049 0.0116 0.0116
Entamoeba histolytica hypothetical protein 0.0032 0.0034 0.025
Brugia malayi MH2 domain containing protein 0.0248 0.1053 0.1694
Brugia malayi hypothetical protein 0.0051 0.0122 0.0197
Echinococcus multilocularis jumonji domain containing 1A 0.0047 0.0104 0.0104
Brugia malayi polk-prov protein 0.0058 0.0159 0.0256
Echinococcus multilocularis lysine specific demethylase 5A 0.0175 0.0709 0.0709
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0099 0.0352 0.0567
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0051 0.0126 0.0126
Loa Loa (eye worm) jmjC domain-containing protein 0.0191 0.0785 0.1263
Schistosoma mansoni retinoic acid receptor RXR 0.0049 0.0116 0.0116
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0056 0.0147 0.0237
Echinococcus multilocularis polycomb protein SCMH1 0.0051 0.0125 0.0125
Echinococcus multilocularis protoporphyrinogen oxidase 0.0051 0.0122 0.0122
Trypanosoma cruzi polo-like protein kinase, putative 0.0201 0.0833 0.1877
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0069 0.0652
Loa Loa (eye worm) hypothetical protein 0.0084 0.028 0.045
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0217 0.0906 0.0906
Echinococcus granulosus jumonji domain containing protein 0.0129 0.0492 0.0492
Brugia malayi Phosphoglycerate kinase 0.0182 0.0743 0.1195
Schistosoma mansoni amine oxidase 0.0051 0.0122 0.0122
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0135 0.052 0.1149
Schistosoma mansoni hypothetical protein 0.0093 0.0321 0.0321
Mycobacterium ulcerans aldehyde dehydrogenase 0.0186 0.0762 0.119
Brugia malayi Glycosyl hydrolases family 31 protein 0.0675 0.3061 0.4924
Brugia malayi Pre-SET motif family protein 0.0126 0.0475 0.0765
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0038 0.0062
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0051 0.0126 0.0203
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0061 0.0171 0.0171
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0047 0.0104 0.0828
Loa Loa (eye worm) glutaminase 0.1345 0.6217 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0062 0.01
Trypanosoma brucei glucosidase, putative 0.015 0.0589 0.1307
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0067 0.02 0.0437
Echinococcus granulosus methyl CpG binding domain protein 2 0.0052 0.0131 0.0131
Brugia malayi Immunoglobulin I-set domain containing protein 0.0339 0.148 0.238
Trypanosoma brucei DNA polymerase IV, putative 0.0118 0.0439 0.0964
Entamoeba histolytica hypothetical protein 0.0074 0.0234 0.1725
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0191 0.0307
Brugia malayi nuclear receptor RXR 0.0026 0.0007 0.0011
Entamoeba histolytica phosphofructokinase, putative 0.0228 0.0959 0.7056
Giardia lamblia Histone acetyltransferase GCN5 0.0082 0.0271 0.1897
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0103 0.0371 0.081
Echinococcus granulosus polycomb protein SCMH1 0.0051 0.0125 0.0125
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0099 0.0352 0.0767

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 5.25 Inhibition of bovine mitochondrial MAOA ChEMBL. 18281126
IC50 (binding) = 5.35 Inhibition of bovine mitochondrial MAOB ChEMBL. 18281126

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.