Detailed information for compound 103630

Basic information

Technical information
  • TDR Targets ID: 103630
  • Name: (2S)-1-[(2S)-1-[2-(2,3-dihydro-1H-inden-2-yl) acetyl]pyrrolidine-2-carbonyl]pyrrolidine-2-c arbonitrile
  • MW: 351.442 | Formula: C21H25N3O2
  • H donors: 0 H acceptors: 3 LogP: 2.27 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#C[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CC1Cc2c(C1)cccc2
  • InChi: 1S/C21H25N3O2/c22-14-18-7-3-9-23(18)21(26)19-8-4-10-24(19)20(25)13-15-11-16-5-1-2-6-17(16)12-15/h1-2,5-6,15,18-19H,3-4,7-13H2/t18-,19-/m0/s1
  • InChiKey: BPDMDQAKGPKONQ-OALUTQOASA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2S)-1-[(2S)-1-(2-indan-2-ylacetyl)pyrrolidine-2-carbonyl]pyrrolidine-2-carbonitrile
  • (2S)-1-[[(2S)-1-[2-(2-indanyl)-1-oxoethyl]-2-pyrrolidinyl]-oxomethyl]-2-pyrrolidinecarbonitrile
  • (2S)-1-[(2S)-1-[2-(2,3-dihydro-1H-inden-2-yl)ethanoyl]pyrrolidin-2-yl]carbonylpyrrolidine-2-carbonitrile
  • (2S)-1-[(2S)-1-(2-indan-2-ylacetyl)prolyl]pyrrolidine-2-carbonitrile

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens prolyl endopeptidase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trypanosoma brucei gambiense prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative Get druggable targets OG5_129295 All targets in OG5_129295
Trypanosoma brucei prolyl endopeptidase Get druggable targets OG5_129295 All targets in OG5_129295
Schistosoma mansoni prolyl oligopeptidase (S09 family) Get druggable targets OG5_129295 All targets in OG5_129295
Onchocerca volvulus Prolyl endopeptidase homolog Get druggable targets OG5_129295 All targets in OG5_129295
Echinococcus granulosus prolyl endopeptidase Get druggable targets OG5_129295 All targets in OG5_129295
Leishmania mexicana prolyl oligopeptidase, putative Get druggable targets OG5_129295 All targets in OG5_129295
Trypanosoma congolense prolyl endopeptidase Get druggable targets OG5_129295 All targets in OG5_129295
Brugia malayi prolyl oligopeptidase family protein Get druggable targets OG5_129295 All targets in OG5_129295
Schistosoma japonicum ko:K01322 prolyl oligopeptidase [EC3.4.21.26], putative Get druggable targets OG5_129295 All targets in OG5_129295
Toxoplasma gondii prolyl endopeptidase Get druggable targets OG5_129295 All targets in OG5_129295
Leishmania infantum prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative Get druggable targets OG5_129295 All targets in OG5_129295
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) Get druggable targets OG5_129295 All targets in OG5_129295
Echinococcus multilocularis prolyl endopeptidase Get druggable targets OG5_129295 All targets in OG5_129295
Schistosoma mansoni prolyl oligopeptidase (S09 family) Get druggable targets OG5_129295 All targets in OG5_129295
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129295 All targets in OG5_129295
Leishmania donovani prolyl endopeptidase Get druggable targets OG5_129295 All targets in OG5_129295
Trypanosoma cruzi prolyl endopeptidase Get druggable targets OG5_129295 All targets in OG5_129295
Neospora caninum Prolyl oligopeptidase (EC 3.4.21.26) (Precursor), related Get druggable targets OG5_129295 All targets in OG5_129295
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative Get druggable targets OG5_129295 All targets in OG5_129295
Schistosoma japonicum Prolyl endopeptidase, putative Get druggable targets OG5_129295 All targets in OG5_129295
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma brucei oligopeptidase b prolyl endopeptidase 710 aa 630 aa 27.0 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0144 0.0281 0.11
Echinococcus multilocularis snurportin 1 0.02 0.0406 0.1592
Echinococcus granulosus neuropeptide Y receptor 0.0144 0.0281 0.1105
Loa Loa (eye worm) hypothetical protein 0.0028 0.0024 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0049 0.0071 0.2447
Plasmodium falciparum cysteine proteinase falcipain 1 0.0027 0.0022 0.0811
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Brugia malayi hypothetical protein 0.0144 0.0281 0.1097
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0049 0.0071 0.2447
Brugia malayi hypothetical protein 0.0144 0.0281 0.1097
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0144 0.0281 0.1105
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0122 0.0233 1
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0463 0.0989 0.658
Onchocerca volvulus Prolyl endopeptidase homolog 0.1165 0.2545 1
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0097 0.0177 0.0697
Trypanosoma cruzi histone deacetylase, putative 0.0027 0.0022 0.008
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0039 0.0082
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0146 0.0286 0.1119
Schistosoma mansoni tsg101-related 0.0031 0.003 0.0111
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0055 0.0084 0.0324
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0006 0.002
Brugia malayi prolyl oligopeptidase family protein 0.0122 0.0233 0.0906
Mycobacterium tuberculosis Conserved protein 0.0035 0.0039 0.0082
Loa Loa (eye worm) neuropeptide F receptor 0.0144 0.0281 0.0281
Loa Loa (eye worm) hypothetical protein 0.0028 0.0024 0.0024
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0144 0.0281 0.0281
Mycobacterium ulcerans recombinase A 0.0065 0.0106 0.1042
Onchocerca volvulus 0.0144 0.0281 0.1089
Brugia malayi hypothetical protein 0.0044 0.006 0.0227
Echinococcus multilocularis inhibitor of apoptosis protein 0.0272 0.0565 0.2219
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0144 0.0281 0.1103
Onchocerca volvulus 0.0144 0.0281 0.1089
Schistosoma mansoni follistatin 0.0019 0.0005 0.0013
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Brugia malayi Peptidase family M1 containing protein 0.0034 0.0037 0.0138
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0006 0.0023
Echinococcus granulosus cathepsin L 0.0027 0.0022 0.0088
Trichomonas vaginalis chromobox protein, putative 0.0049 0.007 0.2427
Echinococcus granulosus inhibitor of apoptosis protein 0.0272 0.0565 0.2221
Schistosoma mansoni zinc finger protein 0.0026 0.0019 0.0071
Entamoeba histolytica cysteine protease, putative 0.0049 0.0071 0.2958
Schistosoma mansoni gamma-secretase subunit aph-1 0.0255 0.0526 0.2064
Echinococcus multilocularis muscleblind protein 0.0187 0.0377 0.1478
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0381 0.0806 0.3166
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0019 0.0004 0.0014
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0008 0.0025
Brugia malayi Melatonin receptor type 1A 0.0144 0.0281 0.1097
Leishmania major cathepsin L-like protease 0.0049 0.0071 0.0274
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0008 0.0191
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0049 0.0071 0.2447
Schistosoma mansoni cercarial elastase (S01 family) 0.005 0.0072 0.0277
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0095 0.0172 0.6084
Schistosoma mansoni hypothetical protein 0.0024 0.0015 0.0054
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0006 0.0025
Leishmania major oligopeptidase b 0.0463 0.0989 0.3883
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0029 0.0025 0.0025
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0039 0.0144
Echinococcus granulosus dro:myosuppressin receptor 0.0144 0.0281 0.1105
Echinococcus granulosus GPCR family 2 0.0029 0.0025 0.0099
Loa Loa (eye worm) hypothetical protein 0.4526 1 1
Toxoplasma gondii NAC domain-containing protein 0.0021 0.0008 0.0024
Echinococcus granulosus orexin receptor type 2 0.0144 0.0281 0.1105
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0032 0.0034 0.0127
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0029 0.0025 0.0095
Schistosoma mansoni hypothetical protein 0.005 0.0072 0.0277
Echinococcus multilocularis rhodopsin orphan GPCR 0.0144 0.0281 0.1103
Toxoplasma gondii HEAT repeat-containing protein 0.0019 0.0003 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0071 0.0274
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0034 0.0037 0.0146
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0049 0.0071 0.2447
Echinococcus multilocularis aminopeptidase N 0.0034 0.0037 0.0144
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0122 0.0233 0.0906
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Plasmodium vivax SET domain protein, putative 0.0019 0.0004 0.0076
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Brugia malayi GnHR receptor homolog 0.0144 0.0281 0.1097
Onchocerca volvulus 0.0049 0.0071 0.0261
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0006 0.0006
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0006 0.0016
Schistosoma mansoni neuropeptide F-like receptor 0.0144 0.0281 0.11
Schistosoma mansoni hypothetical protein 0.0062 0.0099 0.0383
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0005 0.0004
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0144 0.0281 0.1097
Leishmania major histone deacetylase, putative 0.0095 0.0172 0.0671
Brugia malayi hypothetical protein 0.0028 0.0024 0.0087
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0008 0.0025
Onchocerca volvulus 0.002 0.0006 0.0007
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0144 0.0281 0.0281
Echinococcus granulosus neuropeptide receptor A26 0.0144 0.0281 0.1105
Schistosoma mansoni immunophilin 0.0097 0.0177 0.0693
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0034 0.0037 0.0144
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0035 0.0039 0.0038
Brugia malayi Trypsin family protein 0.0432 0.092 0.3609
Schistosoma mansoni jumonji/arid domain-containing protein 0.0047 0.0065 0.025
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0004
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.009 0.0162 0.0629
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0019 0.056
Schistosoma mansoni hypothetical protein 0.0029 0.0025 0.0094
Schistosoma mansoni myosin xvIII 0.0144 0.0281 0.11
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0113 0.0212 0.0211
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0029 0.0025 0.0095
Wolbachia endosymbiont of Brugia malayi recombinase A 0.0065 0.0106 0.2164
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0034 0.0037 0.0144
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Toxoplasma gondii aspartyl protease ASP3 0.0092 0.0166 0.0646
Onchocerca volvulus 0.013 0.025 0.0967
Entamoeba histolytica cysteine protease, putative 0.0027 0.0022 0.0844
Plasmodium falciparum importin beta, putative 0.0019 0.0003 0.0039
Brugia malayi hypothetical protein 0.0124 0.0237 0.0921
Schistosoma mansoni neuropeptide receptor 0.0144 0.0281 0.11
Brugia malayi Peptidase family M1 containing protein 0.0034 0.0037 0.0138
Plasmodium vivax histone deacetylase, putative 0.0027 0.0022 0.078
Echinococcus granulosus hypothetical protein 0.0144 0.0281 0.1105
Echinococcus granulosus laminin 0.0026 0.002 0.0079
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0021 0.0008 0.0025
Loa Loa (eye worm) hypothetical protein 0.0049 0.007 0.0069
Schistosoma mansoni calpain C (C02 family) 0.0021 0.0008 0.0025
Loa Loa (eye worm) hypothetical protein 0.0272 0.0565 0.0565
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0095 0.0172 0.6084
Schistosoma mansoni cercarial elastase (S01 family) 0.005 0.0072 0.0277
Mycobacterium leprae PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase 0.0233 0.0478 0.3038
Onchocerca volvulus Neuropeptide F receptor homolog 0.0144 0.0281 0.1089
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Entamoeba histolytica prolyl oligopeptidase family protein 0.0122 0.0233 1
Loa Loa (eye worm) hypothetical protein 0.0058 0.0091 0.009
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0463 0.0989 0.3883
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0049 0.0071 0.2768
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0113 0.0212 0.0828
Brugia malayi calpain family protein 1 0.0055 0.0084 0.032
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.005 0.0072 0.028
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0006 0.0007
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0144 0.0281 0.1103
Loa Loa (eye worm) hypothetical protein 0.0034 0.0038 0.0037
Trypanosoma cruzi cysteine peptidase, putative 0.0049 0.0071 0.0274
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0039 0.1297
Echinococcus granulosus rhodopsin orphan GPCR 0.0144 0.0281 0.1105
Onchocerca volvulus 0.0144 0.0281 0.1089
Echinococcus multilocularis calpain 0.0021 0.0008 0.0028
Echinococcus granulosus rhodopsin orphan GPCR 0.0144 0.0281 0.1105
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0122 0.0233 0.091
Toxoplasma gondii prolyl endopeptidase 0.1165 0.2545 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0071 0.0274
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0028 0.0024 0.0094
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0144 0.0281 0.11
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.005 0.0072 0.0277
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.005 0.0072 0.0277
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0057 0.0089 0.0345
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0071 0.0274
Brugia malayi Trypsin-like protease protein 5 0.005 0.0072 0.0273
Schistosoma mansoni amine GPCR 0.0144 0.0281 0.11
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0002 0.0007
Brugia malayi mbt repeat family protein 0.0027 0.0021 0.0075
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0003 0.0003
Treponema pallidum recombinase A 0.0065 0.0106 0.2164
Echinococcus multilocularis dnaJ subfamily B 0.0777 0.1685 0.662
Echinococcus granulosus g protein coupled receptor 0.0144 0.0281 0.1105
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0144 0.0281 0.11
Entamoeba histolytica cysteine proteinase, putative 0.0049 0.0071 0.2958
Onchocerca volvulus 0.0144 0.0281 0.1086
Loa Loa (eye worm) hypothetical protein 0.0034 0.0038 0.0037
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0034 0.0037 0.0142
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0029 0.0025 0.0095
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0042 0.0055 0.0214
Echinococcus multilocularis chromobox protein 1 0.0081 0.0142 0.0556
Trypanosoma cruzi Aph-1 protein, putative 0.0099 0.0182 0.0709
Brugia malayi Trypsin family protein 0.005 0.0072 0.0273
Echinococcus multilocularis orexin receptor type 2 0.0144 0.0281 0.1103
Giardia lamblia Cathepsin B precursor 0.0054 0.0081 0.3397
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0144 0.0281 0.1103
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0049 0.0071 0.2447
Entamoeba histolytica aminopeptidase, putative 0.0034 0.0037 0.1493
Loa Loa (eye worm) hypothetical protein 0.0097 0.0177 0.0177
Schistosoma mansoni histone deacetylase 0.0095 0.0172 0.0671
Schistosoma mansoni immunophilin 0.0113 0.0212 0.0828
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0122 0.0233 0.0912
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0038 0.1255
Trypanosoma cruzi Aph-1 protein, putative 0.0099 0.0182 0.0709
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0042 0.0055 0.0212
Onchocerca volvulus 0.0144 0.0281 0.1089
Schistosoma mansoni transcription factor btf3 0.0021 0.0008 0.0028
Leishmania major hypothetical protein, conserved 0.0044 0.006 0.0231
Loa Loa (eye worm) hypothetical protein 0.0187 0.0377 0.0376
Echinococcus granulosus tissue type plasminogen activator 0.013 0.025 0.0983
Brugia malayi calpain family protein 1 0.0055 0.0084 0.032
Schistosoma mansoni growth hormone secretagogue receptor 0.0144 0.0281 0.11
Trypanosoma cruzi cysteine peptidase, putative 0.0049 0.0071 0.0274
Brugia malayi hypothetical protein 0.0144 0.0281 0.1097
Schistosoma mansoni hypothetical protein 0.0336 0.0708 0.2776
Echinococcus multilocularis chromobox protein 1 0.0081 0.0142 0.0556
Plasmodium vivax histone deacetylase 1, putative 0.0095 0.0172 0.6838
Echinococcus multilocularis g-protein coupled receptor 0.0144 0.0281 0.1103
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.02 0.0406 0.0405
Echinococcus multilocularis calpain family protein 1, d 0.004 0.0051 0.02
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0097 0.0177 0.0695
Loa Loa (eye worm) hypothetical protein 0.004 0.0051 0.0051
Schistosoma mansoni opsin-like receptor 0.0144 0.0281 0.11
Schistosoma mansoni cercarial elastase (S01 family) 0.005 0.0072 0.0277
Echinococcus multilocularis cathepsin L cysteine protease 0.0049 0.0071 0.0277
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.005 0.0072 0.0277
Schistosoma mansoni hypothetical protein 0.0144 0.0281 0.11
Trypanosoma cruzi histone deacetylase, putative 0.0027 0.0022 0.008
Schistosoma mansoni cathepsin F (C01 family) 0.0049 0.0071 0.0274
Trypanosoma cruzi histone deacetylase 1, putative 0.0095 0.0172 0.0671
Echinococcus granulosus histone deacetylase 3 0.0095 0.0172 0.0675
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0019 0.0003 0.001
Brugia malayi AKH receptor 0.0144 0.0281 0.1097
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0027 0.0022 0.0083
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0144 0.0281 0.11
Echinococcus granulosus neuropeptide FF receptor 2 0.0144 0.0281 0.1105
Loa Loa (eye worm) trypsin family protein 0.005 0.0072 0.0071
Echinococcus multilocularis histone deacetylase 6 0.0027 0.0022 0.0083
Loa Loa (eye worm) hypothetical protein 0.0034 0.0038 0.0037
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0039 0.1297
Brugia malayi Cathepsin L-like precursor 0.0049 0.0071 0.027
Onchocerca volvulus 0.005 0.0072 0.0265
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0027 0.0022 0.0083
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0113 0.0212 0.0832
Trypanosoma cruzi DNA repair protein, putative 0.002 0.0006 0.0019
Echinococcus multilocularis fmrfamide receptor 0.0144 0.0281 0.1103
Plasmodium vivax unspecified product 0.0027 0.0022 0.0811
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0006 0.002
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0006 0.0016
Schistosoma mansoni sex comb on midleg homolog 0.0027 0.0021 0.0079
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0039 0.1297
Trypanosoma cruzi hypothetical protein, conserved 0.0122 0.0233 0.091
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0146 0.0286 0.1119
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.1873 0.4115 0.9171
Onchocerca volvulus 0.0035 0.0039 0.0136
Mycobacterium ulcerans lipase LipD 0.0035 0.0039 0.0365
Loa Loa (eye worm) calpain family protein 1 0.004 0.0051 0.0051
Toxoplasma gondii ABC1 family protein 0.0035 0.0039 0.0144
Plasmodium falciparum phd finger protein, putative 0.0034 0.0037 0.1403
Onchocerca volvulus 0.0049 0.0071 0.0261
Loa Loa (eye worm) hypothetical protein 0.0122 0.0233 0.0232
Loa Loa (eye worm) hypothetical protein 0.0035 0.0039 0.0038
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0039 0.0082
Onchocerca volvulus 0.0144 0.0281 0.1089
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0021 0.0008 0.0025
Brugia malayi follicle stimulating hormone receptor 0.0144 0.0281 0.1097
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Loa Loa (eye worm) MH2 domain-containing protein 0.0214 0.0437 0.0436
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0113 0.0212 0.845
Brugia malayi hypothetical protein 0.0144 0.0281 0.1097
Onchocerca volvulus 0.0382 0.081 0.317
Giardia lamblia Cathepsin B precursor 0.0054 0.0081 0.3397
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0005 0.0009
Toxoplasma gondii PHD-finger domain-containing protein 0.0034 0.0037 0.0137
Echinococcus multilocularis neuropeptide receptor A26 0.0144 0.0281 0.1103
Toxoplasma gondii kringle domain-containing protein 0.013 0.025 0.0975
Echinococcus granulosus importin subunit beta 1 0.0019 0.0003 0.0013
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0122 0.0233 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0029 0.0025 0.0097
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0035 0.0039 0.0038
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0006 0.0016
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0122 0.0233 0.0914
Brugia malayi Cell death protein 3 precursor 0.0124 0.0237 0.0921
Brugia malayi Histone deacetylase 1 0.0095 0.0172 0.0667
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Schistosoma mansoni hypothetical protein 0.0144 0.0281 0.11
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0122 0.0233 0.0898
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0028 0.0024 0.0024
Brugia malayi Pre-SET motif family protein 0.0019 0.0004 0.0007
Schistosoma mansoni opsin-like receptor 0.0144 0.0281 0.11
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.008 0.0139 0.1377
Trypanosoma cruzi cysteine proteinase, putative 0.0027 0.0022 0.0083
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0034 0.0037 0.0141
Schistosoma mansoni amine GPCR 0.0144 0.0281 0.11
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0002 0.0007
Brugia malayi Dopamine receptor 0.0144 0.0281 0.1097
Echinococcus multilocularis SAM and MBT domain containing protein 0.0027 0.0021 0.0082
Schistosoma mansoni jumonji/arid domain-containing protein 0.0047 0.0065 0.025
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0113 0.0212 0.2118
Brugia malayi hypothetical protein 0.0144 0.0281 0.1097
Schistosoma mansoni hypothetical protein 0.002 0.0006 0.0018
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0005 0.0009
Loa Loa (eye worm) fibroinase 0.0049 0.0071 0.007
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.011 0.0205 0.0805
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0006 0.0103
Mycobacterium tuberculosis Conserved protein 0.0035 0.0039 0.0082
Leishmania major cathepsin L-like protease 0.0049 0.0071 0.0274
Echinococcus granulosus fetal alzheimer antigen falz 0.0029 0.0027 0.0105
Onchocerca volvulus Putative organic anion transporter 0.0028 0.0024 0.0078
Loa Loa (eye worm) hypothetical protein 0.0034 0.0037 0.0037
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0034 0.0037 0.0142
Echinococcus multilocularis cathepsin L cysteine protease 0.0049 0.0071 0.0277
Schistosoma mansoni methyl-cpg binding protein mbd 0.002 0.0006 0.0018
Onchocerca volvulus 0.0036 0.0041 0.0143
Brugia malayi Cathepsin L-like precursor 0.0049 0.0071 0.027
Onchocerca volvulus 0.0028 0.0024 0.0078
Entamoeba histolytica cysteine protease, putative 0.0027 0.0022 0.0844
Loa Loa (eye worm) hypothetical protein 0.0026 0.002 0.002
Trichomonas vaginalis immunophilin, putative 0.0113 0.0212 0.7526
Loa Loa (eye worm) hypothetical protein 0.013 0.025 0.025
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0004
Echinococcus multilocularis g protein coupled receptor 0.0144 0.0281 0.1103
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0029 0.0025 0.0091
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0049 0.0071 0.2447
Trichomonas vaginalis histone deacetylase, putative 0.0095 0.0172 0.6084
Plasmodium falciparum plasmepsin X 0.0092 0.0166 0.662
Echinococcus granulosus SAM and MBT domain containing protein 0.0027 0.0021 0.0084
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0113 0.0212 0.0824
Schistosoma mansoni calpain (C02 family) 0.0021 0.0008 0.0025
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0144 0.0281 0.11
Brugia malayi beta-lactamase 0.0035 0.0039 0.0144
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0034 0.0037 0.0144
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0005 0.0009
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0034 0.0037 0.1235
Trichomonas vaginalis chromobox protein, putative 0.0081 0.0142 0.5004
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0006 0.0025
Schistosoma mansoni hypothetical protein 0.005 0.0072 0.0277
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0019 0.0004 0.0007
Trypanosoma brucei calpain-like protein, putative 0.0021 0.0008 0.0025
Loa Loa (eye worm) hypothetical protein 0.0028 0.0024 0.0024
Brugia malayi histone deacetylase 1 (HD1) 0.0095 0.0172 0.0667
Brugia malayi histone deacetylase 11 0.0027 0.0022 0.0076
Echinococcus multilocularis neuropeptide FF receptor 2 0.0144 0.0281 0.1103
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0008 0.0191
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0049 0.0071 0.0277
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0021 0.0008 0.0025
Echinococcus multilocularis hypothetical protein 0.0021 0.0008 0.0028
Brugia malayi prolyl oligopeptidase family protein 0.0122 0.0233 0.0906
Echinococcus granulosus g-protein coupled receptor 0.0144 0.0281 0.1105
Loa Loa (eye worm) G-protein coupled receptor 0.0144 0.0281 0.0281
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0144 0.0281 0.11
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0028 0.0024 0.0096
Entamoeba histolytica cysteine protease, putative 0.0027 0.0022 0.0844
Echinococcus granulosus polycomb protein SCMH1 0.0027 0.0021 0.0084
Echinococcus multilocularis transcription factor btf3 0.0021 0.0008 0.0031
Brugia malayi F/Y-rich N-terminus family protein 0.0031 0.003 0.0108
Echinococcus granulosus rhodopsin orphan GPCR 0.0144 0.0281 0.1105
Schistosoma mansoni hypothetical protein 0.0168 0.0333 0.1305
Brugia malayi Kringle domain containing protein 0.013 0.025 0.0975
Echinococcus granulosus peptide allatostatin:somatostatin 0.0144 0.0281 0.1105
Toxoplasma gondii LsmAD domain-containing protein 0.0044 0.006 0.0227
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.001
Onchocerca volvulus Putative organic anion transporter 0.0028 0.0024 0.0078
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0039 0.0038
Schistosoma mansoni ap endonuclease 0.0019 0.0003 0.0007
Echinococcus multilocularis dro:myosuppressin receptor 0.0144 0.0281 0.1103
Trypanosoma cruzi oligopeptidase b 0.0463 0.0989 0.3883
Schistosoma mansoni amine GPCR 0.0144 0.0281 0.11
Loa Loa (eye worm) hypothetical protein 0.0028 0.0024 0.0024
Schistosoma mansoni hypothetical protein 0.0034 0.0037 0.0141
Loa Loa (eye worm) histone deacetylase 0.0027 0.0022 0.0021
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0113 0.0212 0.083
Plasmodium vivax vivapain-3 0.0027 0.0022 0.0811
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0006 0.0025
Trypanosoma cruzi cysteine peptidase, putative 0.0049 0.0071 0.0274
Trypanosoma cruzi MFS transporter, putative 0.0028 0.0024 0.0091
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0022 0.0698
Schistosoma mansoni chromobox protein 0.0081 0.0142 0.0553
Brugia malayi Papain family cysteine protease containing protein 0.0027 0.0022 0.0079
Echinococcus multilocularis allatostatin A receptor 0.028 0.0582 0.2284
Schistosoma mansoni cercarial elastase (S01 family) 0.005 0.0072 0.0277
Echinococcus granulosus snurportin 1 0.02 0.0406 0.1594
Onchocerca volvulus 0.0028 0.0024 0.0078
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0144 0.0281 0.1105
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0021
Loa Loa (eye worm) hypothetical protein 0.0026 0.002 0.002
Plasmodium falciparum histone deacetylase, putative 0.0027 0.0022 0.078
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Echinococcus granulosus rhodopsin orphan GPCR 0.0144 0.0281 0.1105
Echinococcus granulosus Solute carrier organic anion transporter family 0.0028 0.0024 0.0096
Onchocerca volvulus 0.0049 0.0071 0.0261
Brugia malayi Histone deacetylase family protein 0.0027 0.0022 0.0076
Entamoeba histolytica cysteine protease, putative 0.0027 0.0022 0.0844
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0006 0.0023
Schistosoma mansoni hypothetical protein 0.0029 0.0025 0.0094
Echinococcus granulosus transmembrane protease serine 3 0.005 0.0072 0.0282
Echinococcus granulosus histone deacetylase 0.0027 0.0022 0.0085
Onchocerca volvulus Alhambra homolog 0.0034 0.0037 0.0128
Giardia lamblia Alanyl dipeptidyl peptidase 0.0122 0.0233 1
Echinococcus granulosus agrin 0.0019 0.0005 0.0018
Echinococcus multilocularis rhodopsin orphan GPCR 0.0144 0.0281 0.1103
Echinococcus granulosus calpain A 0.0021 0.0008 0.003
Echinococcus granulosus neuropeptide s receptor 0.0144 0.0281 0.1105
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0278 0.0579 0.227
Mycobacterium ulcerans replicative DNA helicase DnaB 0.0233 0.0478 0.4813
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0003 0.0002
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase 0.0233 0.0478 1
Brugia malayi Trypsin family protein 0.005 0.0072 0.0273
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0004 0.003
Loa Loa (eye worm) hypothetical protein 0.0229 0.047 0.0469
Echinococcus granulosus calpain 5 0.0021 0.0008 0.003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0038 0.1255
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0039 0.1481
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0122 0.0233 0.091
Toxoplasma gondii PHD-finger domain-containing protein 0.0034 0.0037 0.0137
Brugia malayi Cathepsin L-like precursor 0.0034 0.0038 0.014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0144 0.0281 0.11
Entamoeba histolytica cysteine proteinase 1, putative 0.0027 0.0022 0.0844
Brugia malayi Papain family cysteine protease containing protein 0.0049 0.0071 0.027
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0034 0.0037 0.1235
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0039 0.0148
Mycobacterium ulcerans beta-lactamase 0.0035 0.0039 0.0365
Entamoeba histolytica prolyl oligopeptidase family protein 0.0122 0.0233 1
Brugia malayi hypothetical protein 0.0144 0.0281 0.1097
Onchocerca volvulus Cell death protein 3 homolog 0.0124 0.0237 0.0913
Leishmania major histone deacetylase, putative 0.0095 0.0172 0.0671
Brugia malayi Fibulin-1 precursor 0.0026 0.002 0.007
Schistosoma mansoni agrin 0.0019 0.0005 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.0022 0.0698
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0003 0.0007
Trichomonas vaginalis histone deacetylase, putative 0.0095 0.0172 0.6084
Schistosoma mansoni inhibitor of apoptosis protein 0.0272 0.0565 0.2217
Echinococcus multilocularis histone deacetylase 1 0.0095 0.0172 0.0673
Echinococcus granulosus g protein coupled receptor 0.0144 0.0281 0.1105
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0005 0.0009
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0003 0.001
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0002 0.0004
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0034 0.0037 0.0144
Loa Loa (eye worm) isocitrate dehydrogenase 0.0018 0.0002 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0006 0.0016
Echinococcus granulosus aminopeptidase N 0.0034 0.0037 0.0146
Brugia malayi hypothetical protein 0.0029 0.0025 0.009
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0144 0.0281 0.11
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0006 0.0006
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0006 0.0016
Echinococcus granulosus geminin 0.0336 0.0708 0.278
Schistosoma mansoni neuropeptide F-like receptor 0.0144 0.0281 0.11
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0272 0.0565 0.2217
Brugia malayi Muscleblind-like protein 0.0187 0.0377 0.1472
Echinococcus granulosus follistatin 0.0019 0.0005 0.0018
Echinococcus multilocularis histone deacetylase 7 0.0027 0.0022 0.0083
Echinococcus granulosus survival motor neuron protein 1 0.0229 0.047 0.1845
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0144 0.0281 0.1105
Leishmania major histone deacetylase, putative 0.0027 0.0022 0.008
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0463 0.0989 0.2201
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0018 0.0002 0.0009
Echinococcus granulosus acylamino acid releasing enzyme 0.0122 0.0233 0.0914
Plasmodium vivax aspartyl protease, putative 0.0092 0.0166 0.662
Schistosoma mansoni thyroid hormone receptor 0.002 0.0006 0.002
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1165 0.2545 1
Leishmania major fk506-binding protein 1-like protein 0.0113 0.0212 0.0828
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0071 0.0274
Loa Loa (eye worm) hypothetical protein 0.0027 0.0021 0.0021
Brugia malayi hypothetical protein 0.0229 0.047 0.1838
Brugia malayi hypothetical protein 0.0045 0.0061 0.0233
Echinococcus multilocularis fibrillin 1 0.0026 0.002 0.0077
Loa Loa (eye worm) pigment dispersing factor receptor c 0.009 0.0162 0.0162
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0006 0.0023
Loa Loa (eye worm) histone deacetylase 3 0.0095 0.0172 0.0171
Brugia malayi neuropeptide F receptor 0.0144 0.0281 0.1097
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0049 0.0071 0.2447
Trypanosoma brucei calpain-like protein, putative 0.0021 0.0008 0.0025
Loa Loa (eye worm) hypothetical protein 0.0045 0.0061 0.006
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0006 0.0016
Echinococcus granulosus Mastin 0.005 0.0072 0.0282
Echinococcus multilocularis serotonin receptor 0.0144 0.0281 0.1103
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0049 0.0071 0.2768
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0008 0.0025
Onchocerca volvulus 0.0272 0.0565 0.2207
Echinococcus granulosus G protein coupled receptor 139 0.0144 0.0281 0.1105
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0006 0.0006
Echinococcus multilocularis serotonin receptor 0.0144 0.0281 0.1103
Schistosoma mansoni tsg101-related 0.0038 0.0045 0.0171
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0006 0.0025
Chlamydia trachomatis replicative DNA helicase 0.0233 0.0478 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0071 0.0274
Echinococcus granulosus calpain A 0.0057 0.0089 0.035
Brugia malayi mbt repeat family protein 0.0027 0.0021 0.0075
Schistosoma mansoni neuropeptide f receptor 76f 0.0144 0.0281 0.11
Leishmania major cathepsin L-like protease 0.0049 0.0071 0.0274
Echinococcus multilocularis somatostatin receptor 0.0144 0.0281 0.1103
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0006 0.0016
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0144 0.0281 0.11
Loa Loa (eye worm) hypothetical protein 0.0122 0.0233 0.0232
Echinococcus granulosus rhodopsin orphan GPCR 0.0144 0.0281 0.1105
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0029 0.0027 0.0103
Trypanosoma cruzi histone deacetylase, putative 0.0027 0.0022 0.008
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0113 0.0212 0.0832
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0113 0.0212 0.0828
Echinococcus granulosus histone deacetylase 8 0.0027 0.0022 0.0085
Plasmodium vivax histone deacetylase, putative 0.0027 0.0022 0.078
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0146 0.0286 0.1119
Schistosoma mansoni hypothetical protein 0.0029 0.0025 0.0094
Onchocerca volvulus 0.0144 0.0281 0.1089
Loa Loa (eye worm) CXXC zinc finger family protein 0.0055 0.0083 0.0082
Brugia malayi CXXC zinc finger family protein 0.0055 0.0083 0.0316
Loa Loa (eye worm) hypothetical protein 0.0044 0.006 0.006
Brugia malayi sodium-independent organic anion transporter family protein 0.0028 0.0024 0.0087
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0019 0.056
Plasmodium falciparum histone deacetylase 2 0.0027 0.0022 0.078
Schistosoma mansoni cercarial elastase (S01 family) 0.005 0.0072 0.0277
Schistosoma mansoni neuropeptide receptor 0.0144 0.0281 0.11
Onchocerca volvulus 0.005 0.0072 0.0265
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0144 0.0281 0.1105
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0488 0.1044 0.4102
Brugia malayi Bromodomain containing protein 0.0091 0.0163 0.063
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0144 0.0281 0.0281
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0004
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0005 0.0009
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0272 0.0565 0.2214
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0057 0.0089 0.035
Schistosoma mansoni bromodomain containing protein 0.0077 0.0132 0.0515
Brugia malayi Dopamine receptor protein 2 0.0144 0.0281 0.1097
Echinococcus multilocularis histone deacetylase 8 0.0027 0.0022 0.0083
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0027 0.0022 0.0083
Echinococcus granulosus methyl CpG binding domain protein 2 0.002 0.0006 0.0023
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Trypanosoma brucei calpain-like protein, putative 0.0021 0.0008 0.0025
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0029 0.0025 0.0097
Brugia malayi jmjC domain containing protein 0.0111 0.0209 0.0812
Plasmodium falciparum histone deacetylase 1 0.0095 0.0172 0.6838
Loa Loa (eye worm) hypothetical protein 0.005 0.0072 0.0071
Brugia malayi jmjC domain containing protein 0.0047 0.0065 0.0246
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.005 0.0072 0.0282
Loa Loa (eye worm) hypothetical protein 0.028 0.0582 0.0581
Onchocerca volvulus 0.005 0.0072 0.0265
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0039 0.0151
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0006 0.0006
Echinococcus multilocularis peregrin 0.0037 0.0043 0.0168
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0122 0.0233 0.091
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0039 0.0365
Onchocerca volvulus 0.005 0.0072 0.0265
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.0113 0.0212 0.9097
Loa Loa (eye worm) transcription factor SMAD2 0.0214 0.0437 0.0436
Echinococcus multilocularis histone deacetylase 6 0.0027 0.0022 0.0083
Onchocerca volvulus 0.0049 0.0071 0.0261
Onchocerca volvulus Deterin homolog 0.0272 0.0565 0.2207
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0034 0.0037 0.0146
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0039 0.0082
Trypanosoma cruzi oligopeptidase b 0.0463 0.0989 0.3883
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0033 0.1087
Echinococcus granulosus alpha 1A adrenergic receptor 0.0144 0.0281 0.1105
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0027 0.0022 0.0083
Toxoplasma gondii hypothetical protein 0.0122 0.0233 0.0906
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0003 0.0012
Echinococcus granulosus endonuclease exonuclease phosphatase 0.011 0.0205 0.0807
Schistosoma mansoni histone deacetylase hda2 0.0027 0.0022 0.008
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0463 0.0989 0.3883
Loa Loa (eye worm) cysteine protease 0.0049 0.0071 0.007
Mycobacterium ulcerans lipoprotein LpqF 0.0038 0.0047 0.0443
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0034 0.0037 0.0142
Echinococcus granulosus calpain 0.0021 0.0008 0.003
Leishmania major histone deacetylase, putative 0.0027 0.0022 0.008
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0029 0.0025 0.0099
Mycobacterium ulcerans hypothetical protein 0.0035 0.0039 0.0365
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0006 0.0006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0144 0.0281 0.11
Entamoeba histolytica histone deacetylase, putative 0.0095 0.0172 0.7355
Brugia malayi SPARC precursor 0.0019 0.0005 0.0009
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0019 0.0004 0.0011
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0002 0.0007
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0113 0.0212 0.7526
Echinococcus granulosus chromobox protein 1 0.0081 0.0142 0.0557
Schistosoma mansoni neuropeptide receptor 0.0144 0.0281 0.11
Mycobacterium tuberculosis Probable conserved lipoprotein LpqF 0.0038 0.0047 0.0099
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0104 0.0193 0.0757
Echinococcus multilocularis calpain A 0.0057 0.0089 0.0348
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0432 0.092 0.3611
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0113 0.0212 0.0828
Schistosoma mansoni tsg101-related 0.0038 0.0045 0.0171
Plasmodium vivax importin-beta 2, putative 0.0019 0.0003 0.0039
Toxoplasma gondii transporter, major facilitator family protein 0.0028 0.0024 0.0087
Schistosoma mansoni immunophilin 0.0113 0.0212 0.0828
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0463 0.0989 0.3883
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1043 0.2274 0.5066
Echinococcus granulosus histone lysine methyltransferase setb 0.0039 0.0048 0.019
Echinococcus granulosus tm gpcr rhodopsin 0.0144 0.0281 0.1105
Brugia malayi neuropeptide F receptor 0.0144 0.0281 0.1097
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0008 0.0025
Echinococcus multilocularis neuropeptide s receptor 0.0144 0.0281 0.1103
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Brugia malayi hypothetical protein 0.0144 0.0281 0.1097
Toxoplasma gondii histone deacetylase HDAC5 0.0027 0.0022 0.0076
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0034 0.0037 0.0142
Echinococcus multilocularis rhodopsin orphan GPCR 0.0144 0.0281 0.1103
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0144 0.0281 0.1103
Trypanosoma cruzi hypothetical protein, conserved 0.0122 0.0233 0.091
Plasmodium vivax hypothetical protein, conserved 0.0122 0.0233 0.9286
Brugia malayi cathepsin L-like precursor 0.0034 0.0038 0.014
Echinococcus granulosus zinc finger protein 0.0026 0.0019 0.0075
Echinococcus granulosus cathepsin l1 0.0049 0.0071 0.0279
Loa Loa (eye worm) hypothetical protein 0.0049 0.0071 0.007
Brugia malayi Pre-SET motif family protein 0.0127 0.0242 0.0943
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0122 0.0233 0.091
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0001 0.0002
Brugia malayi hypothetical protein 0.0034 0.0037 0.0138
Echinococcus multilocularis survival motor neuron protein 1 0.0229 0.047 0.1844
Echinococcus granulosus 7TM GPCR rhodopsin 0.0144 0.0281 0.1105
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0031 0.003 0.0114
Echinococcus granulosus Dipeptidyl peptidase 9 0.0122 0.0233 0.0914
Schistosoma mansoni cpg binding protein 0.006 0.0094 0.0367
Onchocerca volvulus Cathepsin F homolog 0.0049 0.0071 0.0261
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0039 0.0082
Schistosoma mansoni hypothetical protein 0.0029 0.0025 0.0094
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.002 0.0006 0.0021
Loa Loa (eye worm) calpain 0.0021 0.0008 0.0007
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0026 0.002 0.002
Brugia malayi Cathepsin L-like precursor 0.0049 0.0071 0.027
Echinococcus multilocularis cysteine protease 0.0049 0.0071 0.0277
Echinococcus multilocularis caspase 2 0.0124 0.0237 0.0927
Schistosoma mansoni cercarial elastase (S01 family) 0.005 0.0072 0.0277
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0028 0.0024 0.0094
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0026 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0028 0.0024 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0063 0.215
Schistosoma mansoni thyroid hormone receptor 0.002 0.0006 0.002
Trypanosoma brucei importin beta-1 subunit, putative 0.0019 0.0003 0.0008
Echinococcus granulosus histone deacetylase 6 0.0027 0.0022 0.0085
Loa Loa (eye worm) hypothetical protein 0.0036 0.0041 0.004
Brugia malayi hypothetical protein 0.0144 0.0281 0.1097
Echinococcus multilocularis prolyl endopeptidase 0.1165 0.2545 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.002 0.002
Treponema pallidum replicative DNA helicase (dnaB) 0.0233 0.0478 1
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0045 0.0061 0.0242
Echinococcus multilocularis histone deacetylase 6 0.0027 0.0022 0.0083
Onchocerca volvulus 0.0124 0.0237 0.0913
Trypanosoma brucei histone deacetylase 4 0.0027 0.0022 0.008
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0002 0.0004
Schistosoma mansoni biogenic amine (5HT) receptor 0.0144 0.0281 0.11
Entamoeba histolytica cysteine protease, putative 0.0027 0.0022 0.0844
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0144 0.0281 0.11
Echinococcus granulosus cathepsin b 0.0146 0.0286 0.1123
Loa Loa (eye worm) hypothetical protein 0.0124 0.0237 0.0236
Echinococcus granulosus neuropeptides capa receptor 0.0144 0.0281 0.1105
Giardia lamblia Alanyl dipeptidyl peptidase 0.0122 0.0233 1
Entamoeba histolytica prolyl oligopeptidase family protein 0.0122 0.0233 1
Brugia malayi gamma-secretase subunit aph-1 0.0255 0.0526 0.206
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0381 0.0806 0.3162
Brugia malayi Tachykinin-like peptides receptor 99D 0.0144 0.0281 0.1097
Echinococcus multilocularis rhodopsin orphan GPCR 0.0144 0.0281 0.1103
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0039 0.0082
Trichomonas vaginalis histone deacetylase, putative 0.0095 0.0172 0.6084
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0027 0.0021 0.0079
Schistosoma mansoni histamine h1 receptor 0.0144 0.0281 0.11
Entamoeba histolytica cysteine protease, putative 0.0027 0.0022 0.0844
Brugia malayi Heterochromatin protein 1 0.0081 0.0142 0.0549
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0029 0.0025 0.0099
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Onchocerca volvulus 0.0028 0.0024 0.0078
Loa Loa (eye worm) hypothetical protein 0.009 0.0162 0.0162
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0122 0.0233 0.091
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0146 0.0286 0.1119
Schistosoma mansoni organic anion transporter 0.0028 0.0024 0.0091
Echinococcus multilocularis neuropeptide Y receptor 0.0144 0.0281 0.1103
Brugia malayi Calcitonin receptor-like protein seb-1 0.009 0.0162 0.0629
Onchocerca volvulus 0.0032 0.0034 0.0115
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0005 0.0009
Plasmodium falciparum basic transcription factor 3b, putative 0.0021 0.0008 0.0244
Echinococcus granulosus biogenic amine 5HT receptor 0.0144 0.0281 0.1105
Brugia malayi Cathepsin L-like precursor 0.0049 0.0071 0.027
Toxoplasma gondii cathepsin B 0.0054 0.0081 0.031
Brugia malayi CHD4 protein 0.0019 0.0003 0.0003
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0018 0.0002 0.0004
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0006 0.0023
Loa Loa (eye worm) G-protein coupled receptor 0.0144 0.0281 0.0281
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0027 0.0021 0.0066
Loa Loa (eye worm) TK/ROR protein kinase 0.013 0.025 0.025
Trypanosoma cruzi cysteine protease, putative 0.0027 0.0022 0.0083
Toxoplasma gondii histone deacetylase HDAC4 0.0027 0.0022 0.0076
Plasmodium vivax vivapain-2 0.0049 0.0071 0.2768
Schistosoma mansoni cercarial elastase (S01 family) 0.005 0.0072 0.0277
Loa Loa (eye worm) MBCTL1 0.0031 0.003 0.0029
Echinococcus multilocularis histone deacetylase 3 0.0095 0.0172 0.0673
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0113 0.0212 0.0824
Echinococcus multilocularis cathepsin L 0.0027 0.0022 0.0086
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0104 0.0193 0.0755
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0039 0.1297
Brugia malayi putative neuropeptide receptor 0.0144 0.0281 0.1097
Onchocerca volvulus 0.0028 0.0024 0.0078
Echinococcus granulosus rhodopsin orphan GPCR 0.0144 0.0281 0.1105
Echinococcus granulosus cpg binding protein 0.006 0.0094 0.0371
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0095 0.0172 0.0171
Entamoeba histolytica cysteine proteinase, putative 0.0027 0.0022 0.0844
Loa Loa (eye worm) hypothetical protein 0.0432 0.092 0.092
Schistosoma mansoni biogenic amine (5HT) receptor 0.0144 0.0281 0.11
Brugia malayi beta-lactamase family protein 0.0035 0.0039 0.0144
Brugia malayi cathepsin B-like cysteine proteinase 0.0146 0.0286 0.1115
Echinococcus multilocularis Mastin 0.005 0.0072 0.028
Onchocerca volvulus Cathepsin L homolog 0.0049 0.0071 0.0261
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0054 0.0081 0.281
Entamoeba histolytica cysteine proteinase, putative 0.0049 0.0071 0.2958
Mycobacterium leprae Conserved hypothetical protein 0.0686 0.1483 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0039 0.0038
Trypanosoma cruzi histone deacetylase, putative 0.0027 0.0022 0.008
Brugia malayi G protein-coupled receptor F59B2.13 0.0144 0.0281 0.1097
Brugia malayi Cathepsin L-like precursor 0.0049 0.0071 0.027
Onchocerca volvulus 0.0035 0.0039 0.0136
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0029 0.0025 0.0099
Onchocerca volvulus 0.0144 0.0281 0.1089
Onchocerca volvulus Histone deacetylase 10 homolog 0.0027 0.0022 0.0067
Trypanosoma cruzi histone deacetylase 1, putative 0.0095 0.0172 0.0671
Trypanosoma cruzi transcription factor btf3, putative 0.0021 0.0008 0.0028
Loa Loa (eye worm) hypothetical protein 0.0035 0.0039 0.0038
Echinococcus granulosus cysteine protease 0.0027 0.0022 0.0088
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.005 0.0072 0.0277
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Mycobacterium tuberculosis Probable replicative DNA helicase DnaB 0.2041 0.4487 1
Loa Loa (eye worm) histone deacetylase 1 0.0095 0.0172 0.0171
Echinococcus multilocularis cpg binding protein 0.006 0.0094 0.0369
Echinococcus granulosus rhodopsin orphan GPCR 0.0144 0.0281 0.1105
Loa Loa (eye worm) prolyl oligopeptidase 0.0122 0.0233 0.0232
Brugia malayi Cathepsin L-like precursor 0.0049 0.0071 0.027
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0144 0.0281 0.11
Brugia malayi histone deacetylase 3 (HD3) 0.0095 0.0172 0.0667
Trypanosoma cruzi cysteine peptidase, putative 0.0049 0.0071 0.0274
Brugia malayi Serotonin receptor 0.0144 0.0281 0.1097
Loa Loa (eye worm) hypothetical protein 0.0034 0.0038 0.0037
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0008 0.0025
Schistosoma mansoni cathepsin F (C01 family) 0.0034 0.0038 0.0144
Onchocerca volvulus 0.0027 0.0021 0.0066
Echinococcus multilocularis neuropeptide receptor 0.0144 0.0281 0.1103
Brugia malayi nuclear receptor NHR-88 0.002 0.0006 0.0016
Toxoplasma gondii histone deacetylase HDAC3 0.0095 0.0172 0.0667
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0049 0.0071 0.2447
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0049 0.0071 0.2447
Loa Loa (eye worm) melatonin receptor type 1A 0.0144 0.0281 0.0281
Loa Loa (eye worm) bromodomain containing protein 0.0021 0.0007 0.0007
Loa Loa (eye worm) calpain family protein 1 0.0055 0.0084 0.0083
Onchocerca volvulus 0.0144 0.0281 0.1089
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0029 0.0025 0.0097
Plasmodium vivax ataxin-2 like protein, putative 0.0044 0.006 0.2332
Entamoeba histolytica cysteine protease, putative 0.0027 0.0022 0.0844
Brugia malayi Calcium binding EGF domain containing protein 0.0026 0.002 0.007
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0019 0.056
Trypanosoma brucei Aminopeptidase M1, putative 0.0034 0.0037 0.0142
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0029 0.0027 0.0101
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.067 0.1448 0.5686
Schistosoma mansoni biogenic amine receptor 0.0144 0.0281 0.11
Trypanosoma cruzi DNA repair protein, putative 0.002 0.0006 0.0019
Trypanosoma brucei PAB1-binding protein , putative 0.0044 0.006 0.0231
Onchocerca volvulus 0.0028 0.0024 0.0078
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Echinococcus granulosus cathepsin b 0.0146 0.0286 0.1123
Leishmania major peptidylprolyl isomerase-like protein 0.0113 0.0212 0.0828
Echinococcus granulosus fmrfamide receptor 0.0144 0.0281 0.1105
Plasmodium vivax calpain, putative 0.0021 0.0008 0.0217
Loa Loa (eye worm) hypothetical protein 0.0146 0.0286 0.0285
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0029 0.0025 0.0097
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0022 0.0011 0.0037
Trypanosoma cruzi aminopeptidase, putative 0.0034 0.0037 0.0142
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0049 0.0071 0.007
Brugia malayi prolyl oligopeptidase family protein 0.0122 0.0233 0.0906
Schistosoma mansoni peptide (allatostatin)-like receptor 0.028 0.0582 0.2281
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0113 0.0212 0.7526
Schistosoma mansoni caspase-7 (C14 family) 0.0124 0.0237 0.0925
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0049 0.0071 0.2447
Brugia malayi prostaglandin transporter 0.0028 0.0024 0.0087
Schistosoma mansoni nuclear hormone receptor 0.002 0.0006 0.002
Giardia lamblia PHD finger protein 15 0.0034 0.0037 0.1484
Echinococcus multilocularis tissue type plasminogen activator 0.013 0.025 0.0982
Echinococcus granulosus neuropeptide Y receptor 0.0144 0.0281 0.1105
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Schistosoma mansoni histone deacetylase hda2 0.0027 0.0022 0.008
Brugia malayi Papain family cysteine protease containing protein 0.0027 0.0022 0.0079
Loa Loa (eye worm) hypothetical protein 0.005 0.0072 0.0071
Brugia malayi beta-lactamase family protein 0.0035 0.0039 0.0144
Echinococcus granulosus glycoprotein Antigen 5 0.005 0.0072 0.0282
Echinococcus multilocularis g protein coupled receptor 0.0144 0.0281 0.1103
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0071 0.0274
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0122 0.0233 0.091
Trypanosoma cruzi prolyl endopeptidase 0.1165 0.2545 1
Loa Loa (eye worm) agrin synaptic family protein 0.0019 0.0005 0.0004
Schistosoma mansoni survival motor neuron protein 0.0047 0.0065 0.0252
Brugia malayi Serotonin receptor 0.0144 0.0281 0.1097
Echinococcus multilocularis rhodopsin orphan GPCR 0.0144 0.0281 0.1103
Leishmania major hypothetical protein, conserved 0.0035 0.0039 0.0148
Brugia malayi larval opioid receptor 0.0144 0.0281 0.1097
Echinococcus granulosus neuropeptides capa receptor 0.0144 0.0281 0.1105
Brugia malayi prolyl oligopeptidase family protein 0.1165 0.2545 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0071 0.0274
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0039 0.0365
Echinococcus multilocularis fmrfamide receptor 0.0144 0.0281 0.1103
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0144 0.0281 0.1097
Echinococcus granulosus enteropeptidase 0.005 0.0072 0.0282
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0006 0.0103
Schistosoma mansoni methyl-cpg binding protein mbd 0.002 0.0006 0.0018
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0272 0.0565 0.2221
Loa Loa (eye worm) hypothetical protein 0.0124 0.0237 0.0236
Brugia malayi hypothetical protein 0.0144 0.0281 0.1097
Brugia malayi steroid hormone receptor 0.002 0.0006 0.0016
Loa Loa (eye worm) hypothetical protein 0.005 0.0072 0.0071
Echinococcus multilocularis sex peptide receptor 0.0144 0.0281 0.1103
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0144 0.0281 0.11
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0144 0.0281 0.11
Loa Loa (eye worm) ctsf protein 0.0049 0.0071 0.007
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0144 0.0281 0.11
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0045 0.0061 0.024
Mycobacterium tuberculosis Class a beta-lactamase BlaC 0.008 0.0139 0.0305
Brugia malayi hypothetical protein 0.005 0.0072 0.0273
Loa Loa (eye worm) hypothetical protein 0.0048 0.0067 0.0067
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0031 0.003 0.1157
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0006 0.0016
Echinococcus multilocularis neuropeptide Y receptor 0.0144 0.0281 0.1103
Echinococcus multilocularis rhodopsin orphan GPCR 0.0144 0.0281 0.1103
Echinococcus multilocularis histone acetyltransferase MYST2 0.0031 0.003 0.0114
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0144 0.0281 0.11
Brugia malayi hypothetical protein 0.0028 0.0024 0.0087
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0039 0.0148
Schistosoma mansoni adenoreceptor 0.0144 0.0281 0.11
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0006 0.002
Echinococcus multilocularis methyl CpG binding domain protein 2 0.002 0.0006 0.002
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0006 0.0016
Schistosoma mansoni cercarial elastase (S01 family) 0.005 0.0072 0.0277
Trypanosoma cruzi cruzipain precursor, putative 0.0049 0.0071 0.0274
Echinococcus multilocularis laminin 0.0026 0.002 0.0077
Echinococcus multilocularis g protein coupled receptor 0.0144 0.0281 0.1103
Echinococcus granulosus jumonji domain containing protein 0.0047 0.0067 0.0262
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0049 0.0071 0.2447
Entamoeba histolytica cysteine protease, putative 0.0027 0.0022 0.0844
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0049 0.0071 0.2447
Entamoeba histolytica cysteine protease, putative 0.0027 0.0022 0.0844
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0049 0.0071 0.2447
Echinococcus granulosus calpain 7 C02 family 0.0021 0.0008 0.003
Schistosoma mansoni cpg binding protein 0.006 0.0094 0.0367
Echinococcus multilocularis histone deacetylase 0.0027 0.0022 0.0083
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Loa Loa (eye worm) hypothetical protein 0.0053 0.0079 0.0078
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0144 0.0281 0.1103
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0144 0.0281 0.0281
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0006 0.0023
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0004
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0039 0.0048 0.0188
Brugia malayi RNA, U transporter 1 0.0053 0.008 0.0305
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0122 0.0233 0.0906
Schistosoma mansoni organic anion transporter 0.0028 0.0024 0.0091
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0008 0.0025
Onchocerca volvulus 0.0144 0.0281 0.1089
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.005 0.0072 0.0277
Schistosoma mansoni hypothetical protein 0.013 0.025 0.0979
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.005 0.0072 0.0273
Trypanosoma brucei antigen, putative 0.0021 0.0008 0.0025
Echinococcus multilocularis neuropeptide receptor 0.0144 0.0281 0.1103
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0019 0.056
Schistosoma mansoni histone deacetylase 0.0095 0.0172 0.0671
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0006 0.0006
Loa Loa (eye worm) mbt repeat family protein 0.0027 0.0021 0.0021
Trichomonas vaginalis fk506-binding protein, putative 0.0113 0.0212 0.7526
Plasmodium vivax basic transcription factor 3b, putative 0.0021 0.0008 0.0244
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0071 0.0274
Plasmodium vivax vivapain-1 0.0027 0.0022 0.0811
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Trichomonas vaginalis histone deacetylase, putative 0.0095 0.0172 0.6084
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0045 0.0061 0.0061
Onchocerca volvulus 0.0144 0.0281 0.1089
Echinococcus multilocularis cathepsin b 0.0146 0.0286 0.1121
Toxoplasma gondii protease inhibitor PI2 0.0019 0.0005 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0049 0.0071 0.2447
Onchocerca volvulus 0.0034 0.0037 0.0129
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.0113 0.0212 0.4401
Loa Loa (eye worm) neuropeptide F receptor 0.0144 0.0281 0.0281
Loa Loa (eye worm) TYRA-2 protein 0.0144 0.0281 0.0281
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. 0.0065 0.0106 0.0462
Mycobacterium ulcerans hypothetical protein 0.005 0.0072 0.0698
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0008 0.0025
Loa Loa (eye worm) hypothetical protein 0.0039 0.0048 0.0048
Onchocerca volvulus 0.0144 0.0281 0.1089
Schistosoma mansoni calpain-7 (C02 family) 0.0023 0.0012 0.0041
Toxoplasma gondii calcium binding egf domain-containing protein 0.0026 0.002 0.007
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0054 0.0081 0.0314
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0381 0.0806 0.3164
Echinococcus granulosus muscleblind protein 0.0187 0.0377 0.1479
Trypanosoma brucei oligopeptidase b 0.0463 0.0989 0.3883
Schistosoma mansoni Mername-AA248 (C02 family) 0.0021 0.0008 0.0025
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0039 0.1297
Leishmania major cathepsin L-like protease 0.0049 0.0071 0.0274
Trypanosoma cruzi cysteine proteinase, putative 0.0027 0.0022 0.0083
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0027 0.0022 0.0083
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0113 0.0212 0.0828
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0026 0.002 0.007
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0006 0.0025
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0144 0.0281 0.1103
Mycobacterium tuberculosis Probable peptidase 0.0463 0.0989 0.2201
Brugia malayi sodium-independent organic anion transporter family protein 0.0028 0.0024 0.0087
Echinococcus granulosus serotonin receptor 0.0144 0.0281 0.1105
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Loa Loa (eye worm) hypothetical protein 0.0026 0.002 0.002
Echinococcus granulosus prolyl endopeptidase 0.1165 0.2545 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.003 0.0029
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0049 0.007 0.0259
Echinococcus multilocularis transmembrane protease serine 3 0.005 0.0072 0.028
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0034 0.0038 0.0144
Entamoeba histolytica cysteine proteinase 2 0.0027 0.0022 0.0844
Loa Loa (eye worm) hypothetical protein 0.0062 0.0099 0.0098
Brugia malayi Trypsin family protein 0.005 0.0072 0.0273
Trypanosoma cruzi hypothetical protein, conserved 0.013 0.025 0.0979
Loa Loa (eye worm) hypothetical protein 0.0272 0.0565 0.0565
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0054 0.0081 0.0314
Schistosoma mansoni importin beta-1 0.0019 0.0003 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0049 0.0071 0.2447
Echinococcus multilocularis cysteine protease 0.0049 0.0071 0.0277
Plasmodium falciparum peptidase, putative 0.0122 0.0233 0.9286
Echinococcus granulosus apoptotic protease activating factor 1 0.0124 0.0237 0.0929
Loa Loa (eye worm) heterochromatin protein 1 0.0081 0.0142 0.0141
Brugia malayi Dopamine receptor protein 1 0.0144 0.0281 0.1097
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0144 0.0281 0.11
Schistosoma mansoni chromobox protein 0.0081 0.0142 0.0553
Loa Loa (eye worm) PHD-finger family protein 0.0034 0.0037 0.0037
Onchocerca volvulus 0.0047 0.0065 0.0239
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0006 0.0016
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0144 0.0281 0.1103
Schistosoma mansoni biogenic amine receptor 0.0144 0.0281 0.11
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0021 0.0008 0.0025
Echinococcus multilocularis Tolloid protein 1 0.0026 0.002 0.0077
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0049 0.0071 0.007
Echinococcus granulosus somatostatin receptor 0.0144 0.0281 0.1105
Loa Loa (eye worm) FKBP5 protein 0.0113 0.0212 0.0211
Echinococcus multilocularis G protein coupled receptor 139 0.0144 0.0281 0.1103
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0122 0.0233 0.091
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0144 0.0281 0.0281
Brugia malayi Histone deacetylase family protein 0.0027 0.0022 0.0076
Schistosoma mansoni hypothetical protein 0.0336 0.0708 0.2776
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0039 0.0048 0.0185
Schistosoma mansoni sex comb on midleg homolog 0.0027 0.0021 0.0079
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Trypanosoma brucei Aph-1 protein, putative 0.0099 0.0182 0.0709
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0049 0.0071 0.2447
Echinococcus granulosus cathepsin l1 0.0034 0.0038 0.0149
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0071 0.0274
Loa Loa (eye worm) hypothetical protein 0.0028 0.0024 0.0024
Echinococcus multilocularis cathepsin b 0.0146 0.0286 0.1121
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0021 0.0008 0.0025
Mycobacterium tuberculosis Conserved protein 0.0035 0.0039 0.0082
Loa Loa (eye worm) histone deacetylase 7A 0.0027 0.0022 0.0021
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0057 0.0089 0.0348
Onchocerca volvulus 0.0049 0.0071 0.0261
Mycobacterium leprae PROBABLE CONSERVED LIPOPROTEIN LPQF 0.0038 0.0047 0.0053
Echinococcus granulosus sex peptide receptor 0.0144 0.0281 0.1105
Entamoeba histolytica hypothetical protein, conserved 0.0122 0.0233 1
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0026 0.002 0.0074
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0019 0.0003 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0063 0.215
Echinococcus granulosus cathepsin l cysteine peptidase 0.0049 0.0071 0.0279
Trypanosoma brucei calpain-like protein, putative 0.0021 0.0008 0.0025
Loa Loa (eye worm) histone deacetylase 11 0.0027 0.0022 0.0021
Onchocerca volvulus Cathepsin L homolog 0.0049 0.0071 0.0261
Schistosoma mansoni cercarial elastase (S01 family) 0.005 0.0072 0.0277
Echinococcus granulosus peregrin 0.0037 0.0043 0.017
Brugia malayi ecdysteroid receptor 0.002 0.0006 0.0016
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0463 0.0989 1
Loa Loa (eye worm) hypothetical protein 0.005 0.0072 0.0071
Brugia malayi secreted modular calcium-binding protein 1 0.0019 0.0005 0.0009
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0144 0.0281 0.1103
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0026 0.002 0.002
Plasmodium falciparum cysteine proteinase falcipain 3 0.0049 0.0071 0.2768
Echinococcus multilocularis acylamino acid releasing enzyme 0.0122 0.0233 0.0912
Loa Loa (eye worm) hypothetical protein 0.0026 0.002 0.002
Schistosoma mansoni cpg binding protein 0.0055 0.0083 0.032
Onchocerca volvulus 0.0144 0.0281 0.1089
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0033 0.1087
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0122 0.0233 0.8273
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0144 0.0281 0.1089
Echinococcus multilocularis isocitrate dehydrogenase 0.0018 0.0002 0.0007
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0039 0.0153
Leishmania major hypothetical protein, conserved 0.013 0.025 0.0979
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0049 0.0071 0.2447
Onchocerca volvulus Putative organic anion transporter 0.0028 0.0024 0.0078
Schistosoma mansoni biogenic amine receptor 0.0144 0.0281 0.11
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0019 0.0005 0.0009
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Schistosoma mansoni cercarial elastase (S01 family) 0.005 0.0072 0.0277
Schistosoma mansoni histone deacetylase 1 2 3 0.0027 0.0022 0.008
Echinococcus multilocularis fk506 binding protein 0.0113 0.0212 0.083
Entamoeba histolytica cysteine protease, putative 0.0027 0.0022 0.0844
Onchocerca volvulus 0.0432 0.092 0.3603
Brugia malayi G-protein coupled receptor 0.0144 0.0281 0.1097
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0021 0.0008 0.0025
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0084 0.0147 0.0575
Trichomonas vaginalis histone deacetylase, putative 0.0095 0.0172 0.6084
Echinococcus multilocularis PHD finger protein rhinoceros 0.0034 0.0037 0.0144
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0039 0.0148
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0034 0.0037 0.0144
Onchocerca volvulus 0.028 0.0582 0.2271
Giardia lamblia Cathepsin B precursor 0.0054 0.0081 0.3397
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0049 0.0071 0.2447
Trichomonas vaginalis histone deacetylase, putative 0.0095 0.0172 0.6084
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0111 0.0209 0.0818
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0272 0.0565 0.2219
Schistosoma mansoni Replicative DNA helicase 0.0233 0.0478 0.1873
Echinococcus multilocularis agrin 0.0019 0.0005 0.0016
Trichomonas vaginalis set domain proteins, putative 0.0144 0.0281 1
Onchocerca volvulus 0.0144 0.0281 0.1089
Trypanosoma brucei cysteine peptidase C (CPC) 0.0054 0.0081 0.0314
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Brugia malayi hypothetical protein 0.0144 0.0281 0.1097
Trichomonas vaginalis conserved hypothetical protein 0.0122 0.0233 0.8273
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0019 0.056
Loa Loa (eye worm) hypothetical protein 0.0432 0.092 0.092
Loa Loa (eye worm) twinkle helicase 0.0066 0.0109 0.0109
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0027 0.0022 0.0083
Loa Loa (eye worm) jmjC domain-containing protein 0.0047 0.0065 0.0064
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0006 0.002
Echinococcus multilocularis GPCR, family 2 0.0029 0.0025 0.0097
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0049 0.0071 0.2447
Trypanosoma brucei histone deacetylase 3 0.0027 0.0022 0.008
Echinococcus multilocularis gamma secretase subunit aph 1 0.0255 0.0526 0.2066
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0018 0.0002 0.0004
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0006 0.0025
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0049 0.0071 0.2447
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0006 0.0016
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Schistosoma mansoni opsin-like receptor 0.0144 0.0281 0.11
Brugia malayi putative neuropeptide receptor NPR1 0.0144 0.0281 0.1097
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.001
Schistosoma mansoni family M1 non-peptidase homologue (M01 family) 0.0022 0.0011 0.0037
Toxoplasma gondii histone lysine methyltransferase SET1 0.0107 0.0199 0.0772
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0019 0.0005 0.0009
Schistosoma mansoni egf-like domain protein 0.0026 0.002 0.0074
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0002 0.0004
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0029 0.0025 0.009
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0073 0.0123 0.0483
Echinococcus granulosus chromobox protein 1 0.0081 0.0142 0.0557
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0122 0.0233 0.0912
Echinococcus multilocularis zinc finger protein 0.0026 0.0019 0.0073
Onchocerca volvulus 0.0034 0.0037 0.0129
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0122 0.0233 0.091
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0008 0.0191
Schistosoma mansoni cercarial elastase (S01 family) 0.005 0.0072 0.0277
Trypanosoma brucei recA bacterial DNA recombination protein, putative 0.002 0.0006 0.0019
Brugia malayi nuclear hormone receptor 0.002 0.0006 0.0016
Loa Loa (eye worm) hypothetical protein 0.005 0.0072 0.0071
Echinococcus multilocularis glycoprotein Antigen 5 0.005 0.0072 0.028
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0006 0.0023
Schistosoma mansoni cathepsin D (A01 family) 0.0106 0.0196 0.0767
Onchocerca volvulus 0.0055 0.0083 0.0307
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Echinococcus granulosus histone deacetylase 6 0.0027 0.0022 0.0085
Echinococcus granulosus lysine specific demethylase 5A 0.0047 0.0065 0.0254
Brugia malayi beta-NAC-like protein 0.0021 0.0008 0.0024
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0144 0.0281 0.1097
Schistosoma mansoni alpha-1 adrenergic receptor 0.0144 0.0281 0.11
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0039 0.0048 0.0185
Entamoeba histolytica hypothetical protein 0.0021 0.0008 0.0231
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Toxoplasma gondii exonuclease III APE 0.0019 0.0003 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0039 0.0148
Schistosoma mansoni myelin transcription factor 1 myt1 0.0031 0.003 0.0112
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0113 0.0212 0.9097
Loa Loa (eye worm) beta-lactamase 0.0035 0.0039 0.0038
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0008 0.0025
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0144 0.0281 0.1097
Echinococcus granulosus caspase 2 0.0124 0.0237 0.0929
Trypanosoma cruzi PAB1-binding protein , putative 0.0044 0.006 0.0231
Echinococcus multilocularis importin subunit beta 1 0.0019 0.0003 0.0011
Schistosoma mansoni hypothetical protein 0.0777 0.1685 0.662
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0006 0.0023
Trypanosoma brucei histone deacetylase, putative 0.0027 0.0022 0.008
Trypanosoma cruzi Aminopeptidase M1, putative 0.0034 0.0037 0.0142
Trypanosoma brucei beta lactamase 0.0038 0.0047 0.0179
Plasmodium falciparum plasmepsin IX 0.0092 0.0166 0.662
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0113 0.0212 0.0828
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Schistosoma mansoni calpain-7 (C02 family) 0.0023 0.0012 0.0041
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0146 0.0286 0.1119
Echinococcus granulosus histone deacetylase 1 0.0095 0.0172 0.0675
Schistosoma mansoni hypothetical protein 0.02 0.0406 0.159
Loa Loa (eye worm) hypothetical protein 0.1165 0.2545 0.2545
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0144 0.0281 0.1105
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0006 0.0023
Echinococcus multilocularis geminin 0.0336 0.0708 0.2778
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0019 0.056
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0039 0.0148
Trypanosoma brucei importin beta-1 subunit, putative 0.0019 0.0003 0.0008
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0049 0.0071 0.0277
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0037 0.1403
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0122 0.0233 0.091
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0049 0.0071 0.2447
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0113 0.0212 0.9097
Echinococcus multilocularis polycomb protein SCMH1 0.0027 0.0021 0.0082
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0039 0.0082
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0006 0.0025
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0255 0.0526 0.0526
Brugia malayi calpain 7 0.0021 0.0008 0.0021
Echinococcus granulosus biogenic amine 5HT receptor 0.0144 0.0281 0.1105
Echinococcus granulosus cathepsin L cysteine protease 0.0027 0.0022 0.0088
Schistosoma mansoni cathepsin F (C01 family) 0.0049 0.0071 0.0274
Plasmodium falciparum ataxin-2 like protein, putative 0.0044 0.006 0.2332
Echinococcus granulosus gamma secretase subunit aph 1 0.0255 0.0526 0.2067
Loa Loa (eye worm) jmjC domain-containing protein 0.007 0.0117 0.0117
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0003 0.003
Onchocerca volvulus 0.0049 0.0071 0.0261
Brugia malayi G protein-coupled receptor 0.0144 0.0281 0.1097
Onchocerca volvulus 0.0049 0.0071 0.0261
Echinococcus multilocularis lysine specific demethylase 5A 0.0041 0.0053 0.0206
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0006 0.0007
Echinococcus granulosus neuropeptide receptor 0.0144 0.0281 0.1105
Echinococcus granulosus dnaJ subfamily B 0.0777 0.1685 0.6621
Loa Loa (eye worm) hypothetical protein 0.0029 0.0025 0.0025
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0021 0.0008 0.0025
Brugia malayi Subtilase family protein 0.0278 0.0579 0.2267
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0054 0.0081 0.0314
Echinococcus multilocularis neuropeptides capa receptor 0.0144 0.0281 0.1103
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0006 0.0016
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0111 0.0209 0.082
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0031 0.003 0.0116
Leishmania major cathepsin L-like protease 0.0049 0.0071 0.0274
Loa Loa (eye worm) hypothetical protein 0.0028 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0187 0.0377 0.0376
Echinococcus granulosus tachykinin peptides receptor 99D 0.0144 0.0281 0.1105
Schistosoma mansoni amine GPCR 0.0144 0.0281 0.11
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0018 0.0002 0.0007
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0272 0.0565 0.2214
Loa Loa (eye worm) hypothetical protein 0.0083 0.0145 0.0144
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0065 0.0248
Plasmodium vivax aspartyl protease, putative 0.0092 0.0166 0.662
Schistosoma mansoni hypothetical protein 0.0047 0.0065 0.0252
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0019 0.056
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.005 0.0072 0.0282
Brugia malayi PHD-finger family protein 0.0034 0.0037 0.0137
Brugia malayi Cathepsin L-like cysteine proteinase 0.0034 0.0038 0.014
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0127 0.0242 0.0242
Trichomonas vaginalis chromobox protein, putative 0.0081 0.0142 0.5004
Giardia lamblia Histone deacetylase 0.0095 0.0172 0.7355
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.1165 0.2545 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0025 0.0018 0.0065
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0019 0.0003 0.0012
Echinococcus multilocularis muscleblind protein 1 0.0187 0.0377 0.1478
Echinococcus multilocularis neuropeptides capa receptor 0.0144 0.0281 0.1103
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0034 0.0037 0.0146
Echinococcus granulosus histone deacetylase 7 0.0027 0.0022 0.0085
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0095 0.0172 0.6084
Schistosoma mansoni hypothetical protein 0.0124 0.0237 0.0925
Onchocerca volvulus 0.0144 0.0281 0.1089
Echinococcus granulosus histone deacetylase 6 0.0027 0.0022 0.0085
Schistosoma mansoni coup transcription factor 0.002 0.0006 0.002
Plasmodium falciparum cysteine repeat modular protein 1 0.013 0.025 1
Toxoplasma gondii histone deacetylase HDAC1 0.0027 0.0022 0.0076
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0049 0.0071 0.2447
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0144 0.0281 0.11
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0018 0.0002 0.0004
Onchocerca volvulus Arrow homolog 0.0026 0.002 0.0061
Echinococcus granulosus tm gpcr rhodopsin 0.0144 0.0281 0.1105
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0144 0.0281 0.1097
Loa Loa (eye worm) subtilase 0.0278 0.0579 0.0578
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0034 0.0037 0.0146
Echinococcus granulosus histone acetyltransferase MYST2 0.0031 0.003 0.0116
Echinococcus multilocularis rhodopsin orphan GPCR 0.0144 0.0281 0.1103
Loa Loa (eye worm) ICD-1 protein 0.0021 0.0008 0.0008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0006 0.0006
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0116 0.022 0.0859
Trypanosoma cruzi cysteine peptidase, putative 0.0027 0.0022 0.0083
Leishmania major basic transcription factor 3a, putative 0.0021 0.0008 0.0028
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0003 0.003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0049 0.0071 0.2447
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0122 0.0233 0.091
Entamoeba histolytica cysteine proteinase, putative 0.0027 0.0022 0.0844
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0463 0.0989 0.3883
Onchocerca volvulus 0.0034 0.0038 0.0131
Leishmania major cathepsin L-like protease 0.0049 0.0071 0.0274
Loa Loa (eye worm) aminopeptidase N 0.0034 0.0037 0.0037
Loa Loa (eye worm) latrophilin receptor protein 2 0.0029 0.0025 0.0025
Echinococcus granulosus g protein coupled receptor 0.0144 0.0281 0.1105
Brugia malayi RE15519p 0.0144 0.0281 0.1097
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0031 0.003 0.0108
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0049 0.0071 0.2447
Mycobacterium ulcerans aminopeptidase N PepN 0.0034 0.0037 0.0348
Brugia malayi prolyl oligopeptidase family protein 0.0122 0.0233 0.0906
Brugia malayi sulfakinin receptor protein 0.0144 0.0281 0.1097
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0006 0.002
Echinococcus granulosus PHD finger protein rhinoceros 0.0034 0.0037 0.0146
Echinococcus granulosus 7tm_1 domain containing protein 0.0144 0.0281 0.1105
Loa Loa (eye worm) PHD-finger family protein 0.0024 0.0015 0.0014
Trypanosoma cruzi histone deacetylase, putative 0.0027 0.0022 0.008
Loa Loa (eye worm) hypothetical protein 0.0035 0.0039 0.0038
Brugia malayi MH2 domain containing protein 0.0214 0.0437 0.1709
Plasmodium vivax vivapain-2 0.0049 0.0071 0.2768
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0071 0.0274
Echinococcus multilocularis rhodopsin orphan GPCR 0.0144 0.0281 0.1103
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0034 0.0037 0.0142
Echinococcus multilocularis G-protein coupled receptor, putative 0.0144 0.0281 0.1103
Schistosoma mansoni hypothetical protein 0.0272 0.0565 0.2217
Schistosoma mansoni neuropeptide receptor 0.0144 0.0281 0.11
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0144 0.0281 0.11
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0113 0.0212 0.0828
Echinococcus granulosus transcription factor btf3 0.0021 0.0008 0.0033
Echinococcus granulosus Tolloid protein 1 0.0026 0.002 0.0079
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0006 0.0023
Trypanosoma cruzi PAB1-binding protein , putative 0.0044 0.006 0.0231
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0144 0.0281 0.1103
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.005 0.0072 0.028
Brugia malayi Latrophilin receptor protein 2 0.0029 0.0025 0.009
Brugia malayi Bromodomain containing protein 0.0037 0.0043 0.0161
Brugia malayi PHD-finger family protein 0.0032 0.0033 0.0121
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0223 0.0456 0.1012
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0006 0.002
Echinococcus granulosus cathepsin L cysteine proteinase 0.0049 0.0071 0.0279
Echinococcus granulosus neuropeptide receptor 0.0144 0.0281 0.1105
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0022 0.0011 0.004
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.0038 0.1517
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0006 0.0016
Entamoeba histolytica transcription factor BTF3, putative 0.0021 0.0008 0.0231
Schistosoma mansoni hypothetical protein 0.0144 0.0281 0.11
Brugia malayi G-protein coupled receptor 0.0144 0.0281 0.1097
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Leishmania major cathepsin L-like protease 0.0049 0.0071 0.0274
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0432 0.092 0.3611
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0113 0.0212 0.9097
Echinococcus granulosus tm gpcr rhodopsin 0.067 0.1448 0.5687
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0003 0.0007
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0122 0.0233 0.8273
Echinococcus multilocularis follistatin 0.0019 0.0005 0.0016
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.1165 0.2545 1
Loa Loa (eye worm) hypothetical protein 0.0055 0.0084 0.0083
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0073 0.0123 0.0481
Trichomonas vaginalis hypothetical protein 0.0022 0.001 0.0262
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0049 0.0071 0.2447
Trichomonas vaginalis chromobox protein, putative 0.0049 0.007 0.2427
Trypanosoma brucei Aminopeptidase M1, putative 0.0034 0.0037 0.0142
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0006 0.0016
Plasmodium vivax cysteine repeat modular protein 1, putative 0.013 0.025 1
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0113 0.0212 0.0828
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0003 0.0002
Onchocerca volvulus 0.0144 0.0281 0.1089
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0144 0.0281 0.11
Trypanosoma brucei transcription factor BTF3, putative 0.0021 0.0008 0.0028
Trypanosoma brucei prolyl oligopeptidase, putative 0.0463 0.0989 0.3883
Echinococcus multilocularis calpain 7 (C02 family) 0.0021 0.0008 0.0028
Schistosoma mansoni histone deacetylase 4 5 0.0027 0.0022 0.008
Echinococcus multilocularis expressed protein 0.0019 0.0005 0.0016
Echinococcus granulosus allatostatin A receptor 0.028 0.0582 0.2285
Loa Loa (eye worm) cathepsin B 0.0054 0.0081 0.008
Schistosoma mansoni histone deacetylase 4 5 0.0027 0.0022 0.008
Brugia malayi Importin beta-1 subunit 0.0019 0.0003 0.0004
Entamoeba histolytica cysteine proteinase, putative 0.0027 0.0022 0.0844
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0006 0.0016
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0019 0.056
Entamoeba histolytica cysteine proteinase, putative 0.0027 0.0022 0.0844
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0144 0.0281 0.11
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0029 0.0025 0.0099
Leishmania major cathepsin L-like protease 0.0049 0.0071 0.0274
Brugia malayi Bromodomain containing protein 0.0045 0.0061 0.023
Trypanosoma brucei histone deacetylase 1 0.0095 0.0172 0.0671
Schistosoma mansoni amine GPCR 0.0144 0.0281 0.11
Trypanosoma cruzi transcription factor btf3, putative 0.0021 0.0008 0.0028
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Plasmodium vivax histone deacetylase 2, putative 0.0027 0.0022 0.078
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.002 0.0006 0.0023
Onchocerca volvulus 0.0144 0.0281 0.1089
Trypanosoma brucei histone deacetylase 2 0.0027 0.0022 0.008
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0006 0.0016
Brugia malayi sodium-independent organic anion transporter family protein 0.0028 0.0024 0.0087
Loa Loa (eye worm) hypothetical protein 0.0046 0.0063 0.0062
Brugia malayi ORL1-like opioid receptor 0.0144 0.0281 0.1097
Trichomonas vaginalis esterase, putative 0.0035 0.0039 0.1297
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0057 0.0089 0.0345
Toxoplasma gondii histone deacetylase HDAC2 0.0095 0.0172 0.0667
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0113 0.0212 0.845
Loa Loa (eye worm) prolyl oligopeptidase 0.0122 0.0233 0.0232
Echinococcus multilocularis jumonji domain containing protein 0.0047 0.0067 0.026
Brugia malayi latrophilin 2 splice variant baaae 0.0062 0.0099 0.0379
Onchocerca volvulus 0.0035 0.0039 0.0136
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0144 0.0281 0.1103
Schistosoma mansoni cathepsin D (A01 family) 0.0106 0.0196 0.0767
Loa Loa (eye worm) hypothetical protein 0.0144 0.0281 0.0281
Entamoeba histolytica cysteine protease, putative 0.0027 0.0022 0.0844
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0039 0.0082
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0144 0.0281 0.1103
Toxoplasma gondii cathepsin CPL 0.0049 0.0071 0.027
Leishmania major cysteine peptidase A (CPA) 0.0049 0.0071 0.0274
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0006 0.002
Onchocerca volvulus 0.0034 0.0038 0.013
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0034 0.0037 0.0144
Loa Loa (eye worm) CHromoDomain protein family member 0.0019 0.0003 0.0002
Entamoeba histolytica cysteine protease, putative 0.0027 0.0022 0.0844
Echinococcus multilocularis enteropeptidase 0.005 0.0072 0.028
Echinococcus multilocularis apoptotic protease activating factor 1 0.0124 0.0237 0.0927
Brugia malayi Cathepsin L-like precursor 0.0034 0.0038 0.014
Schistosoma mansoni ap endonuclease 0.0019 0.0003 0.0007
Toxoplasma gondii calcium binding egf domain-containing protein 0.0026 0.002 0.007
Echinococcus multilocularis calpain 5 0.0021 0.0008 0.0028
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0144 0.0281 0.1103
Schistosoma mansoni jumonji domain containing protein 0.0089 0.0158 0.0616
Brugia malayi chromobox protein homolog 3 0.0046 0.0063 0.0238
Echinococcus granulosus FTZ F1 alpha 0.002 0.0006 0.0025
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0006 0.0025
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0006 0.002
Brugia malayi Protein kinase domain containing protein 0.013 0.025 0.0975
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0046 0.0063 0.0229
Trypanosoma brucei prolyl endopeptidase 0.1165 0.2545 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0049 0.0071 0.0274
Entamoeba histolytica cysteine protease, putative 0.0027 0.0022 0.0844
Onchocerca volvulus 0.005 0.0072 0.0265
Plasmodium falciparum ataxin-2 like protein, putative 0.0044 0.006 0.2332
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0006 0.002

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 1.2 nM In vitro inhibitory activity against purified prolyl endopeptidase (PEP) from canine brain. ChEMBL. 8027988
IC50 (binding) = 1.2 nM In vitro inhibitory activity against purified prolyl endopeptidase (PEP) from canine brain. ChEMBL. 8027988

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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