Detailed information for compound 107883

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 269.161 | Formula: C10H9BrN2S
  • H donors: 1 H acceptors: 0 LogP: 2.11 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: Brc1ccc(cc1)Cn1cc[nH]c1=S
  • InChi: 1S/C10H9BrN2S/c11-9-3-1-8(2-4-9)7-13-6-5-12-10(13)14/h1-6H,7H2,(H,12,14)
  • InChiKey: VBXGFPDEUDCBNG-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus lamin dm0 0.0022 0.0079 0.0156
Onchocerca volvulus Cathepsin F homolog 0.001 0.0013 0.0124
Brugia malayi Sodium:neurotransmitter symporter family protein 0.002 0.0071 0.0422
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0013 0.0029 0.0028
Plasmodium vivax phosphodiesterase gamma, putative 0.001 0.0014 0.0218
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.0104 0.1206
Schistosoma mansoni coup transcription factor 0.0023 0.0087 0.0127
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.002 0.0071 0.0071
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0149 0.022
Loa Loa (eye worm) ctsf protein 0.001 0.0013 0.0024
Schistosoma mansoni biogenic amine receptor 0.007 0.0346 0.0512
Schistosoma mansoni peptide (allatostatin)-like receptor 0.007 0.0346 0.0512
Echinococcus granulosus peptide allatostatin:somatostatin 0.007 0.0346 0.0691
Plasmodium falciparum thioredoxin reductase 0.0029 0.0119 0.2004
Mycobacterium ulcerans acyl-CoA synthetase 0.0011 0.0019 0.1144
Onchocerca volvulus 0.007 0.0346 0.3595
Loa Loa (eye worm) neuropeptide F receptor 0.007 0.0346 0.0691
Brugia malayi hypothetical protein 0.0011 0.002 0.0116
Leishmania major cytochrome p450-like protein 0.0012 0.0025 0.0273
Brugia malayi mbt repeat family protein 0.0038 0.017 0.1008
Loa Loa (eye worm) hypothetical protein 0.0038 0.017 0.0339
Brugia malayi Nuclear hormone receptor E75 0.0011 0.002 0.0116
Onchocerca volvulus 0.007 0.0346 0.3595
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0028 0.0112 0.1315
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.002 0.0071 0.0141
Leishmania major cathepsin L-like protease 0.0037 0.0163 0.3414
Echinococcus granulosus replication factor c subunit 1 0.0007 0.0001 0.00000068899
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.001 0.0014 0.0019
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0035 0.0154 0.1394
Trichomonas vaginalis D-aminoacylase, putative 0.0023 0.0088 0.0791
Leishmania major dihydrolipoamide dehydrogenase, putative 0.001 0.0015 0.0043
Echinococcus granulosus o acyltransferase membrane bound domain 0.0089 0.0451 0.0902
Plasmodium vivax amine transporter, putative 0.002 0.0071 0.1199
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.002 0.0071 0.0422
Onchocerca volvulus 0.0009 0.0011 0.0105
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0013 0.0108
Loa Loa (eye worm) solute carrier family 6 member 4 0.0119 0.0619 0.1237
Onchocerca volvulus 0.007 0.0346 0.3595
Leishmania major glycerol uptake protein, putative 0.0089 0.0451 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.007 0.0346 0.0512
Loa Loa (eye worm) hypothetical protein 0.0181 0.0962 0.1923
Loa Loa (eye worm) LBP/BPI/CETP family domain-containing protein 0.0036 0.0157 0.0312
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0108 0.056 0.0559
Loa Loa (eye worm) hypothetical protein 0.0023 0.0088 0.0174
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0023 0.0087 0.0172
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.001 0.0015 0.0307
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.001 0.0014 0.0027
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0026
Echinococcus multilocularis rhodopsin orphan GPCR 0.007 0.0346 0.0345
Brugia malayi LBP/BPI 0.0015 0.0044 0.0258
Brugia malayi intermediate filament protein 0.0022 0.0079 0.0466
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.001 0.0014 0.0117
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.001 0.0013 0.0108
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0023 0.0087 0.0172
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0089 0.0451 0.0902
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.001 0.0013 0.0108
Loa Loa (eye worm) hypothetical protein 0.0009 0.0011 0.002
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0089 0.0451 0.5582
Leishmania major 4-coumarate:coa ligase-like protein 0.0037 0.0164 0.3444
Brugia malayi Cytochrome P450 family protein 0.0012 0.0025 0.0146
Schistosoma mansoni lamin 0.0022 0.0079 0.0115
Echinococcus multilocularis g protein coupled receptor 0.007 0.0346 0.0345
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0051 0.0243 0.0485
Echinococcus multilocularis sex peptide receptor 0.007 0.0346 0.0345
Brugia malayi Isocitrate dehydrogenase 0.0013 0.0029 0.0173
Schistosoma mansoni biogenic amine receptor 0.007 0.0346 0.0512
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0073 0.0363 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.001 0.0013 0.0108
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0028 0.0112 0.6831
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.001 0.0014 0.0027
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0023 0.0088 0.5337
Echinococcus granulosus Protein patched homolog 1 0.0066 0.0324 0.0646
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.001 0.0014 0.0019
Brugia malayi MBOAT family protein 0.0089 0.0451 0.2673
Onchocerca volvulus 0.001 0.0013 0.0124
Onchocerca volvulus 0.0009 0.0011 0.0105
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0023 0.0088 0.0998
Loa Loa (eye worm) oxidoreductase 0.0011 0.0019 0.0037
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0066 0.0323 0.4055
Trypanosoma cruzi glycerol uptake protein, putative 0.0089 0.0451 1
Echinococcus granulosus thyrotropin releasing hormone receptor 0.007 0.0346 0.0691
Loa Loa (eye worm) hypothetical protein 0.0009 0.0011 0.002
Plasmodium falciparum plasmepsin IX 0.0114 0.0589 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0162 0.0857 0.5073
Loa Loa (eye worm) latrophilin receptor protein 2 0.0051 0.0243 0.0485
Leishmania major cathepsin L-like protease 0.0037 0.0163 0.3414
Mycobacterium leprae Probable lipase LipE 0.0023 0.0088 0.24
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0089 0.0451 0.0451
Toxoplasma gondii ABC1 family protein 0.0023 0.0088 0.0186
Echinococcus granulosus protein kinase c iota type 0.0052 0.0248 0.0494
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0089 0.0451 0.0902
Leishmania major glycerol uptake protein, putative 0.0089 0.0451 1
Onchocerca volvulus 0.0034 0.0149 0.1543
Schistosoma mansoni hypothetical protein 0.0051 0.0243 0.036
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0029 0.0122 0.0722
Echinococcus multilocularis cathepsin L cysteine protease 0.001 0.0013 0.0012
Echinococcus multilocularis GPCR, family 2 0.0051 0.0243 0.0243
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0035 0.0154 0.0307
Mycobacterium leprae conserved hypothetical protein 0.0025 0.01 0.2735
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0035 0.0154 0.3403
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0027 0.0158
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0089 0.0451 0.5582
Loa Loa (eye worm) hypothetical protein 0.0023 0.0087 0.0172
Brugia malayi LBP / BPI / CETP family, C-terminal domain containing protein 0.002 0.0073 0.043
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.007 0.0346 0.3595
Loa Loa (eye worm) hypothetical protein 0.0035 0.0154 0.0307
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0011 0.0019 0.0153
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0033 0.0145 0.3197
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0035 0.0154 0.1394
Brugia malayi Dopamine receptor protein 1 0.007 0.0346 0.205
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0037
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0089 0.0451 0.0668
Loa Loa (eye worm) hypothetical protein 0.0084 0.0424 0.0847
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0011 0.002 0.0028
Echinococcus granulosus protein kinase c epsilon type 0.0008 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0023 0.0087 0.0172
Echinococcus granulosus sterol O acyltransferase 1 0.0909 0.4997 1
Mycobacterium ulcerans hypothetical protein 0.0023 0.0088 0.5337
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.0087 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.01 0.0901
Echinococcus multilocularis serotonin receptor 0.007 0.0346 0.0345
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0088 0.24
Trichomonas vaginalis esterase, putative 0.0023 0.0088 0.0791
Toxoplasma gondii patched family protein 0.0009 0.0011 0.0022
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0011 0.0019 0.0414
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.001 0.0015 0.0235
Brugia malayi Cathepsin L-like precursor 0.001 0.0013 0.0076
Brugia malayi Cathepsin L-like precursor 0.001 0.0013 0.0076
Echinococcus granulosus g protein coupled receptor 0.007 0.0346 0.0691
Plasmodium vivax aspartyl proteinase, putative 0.0108 0.056 0.9508
Echinococcus multilocularis fmrfamide receptor 0.007 0.0346 0.0345
Loa Loa (eye worm) beta-lactamase 0.0023 0.0088 0.0174
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0011 0.0019 0.0109
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.001 0.0013 0.0108
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0037 0.0164 0.4497
Echinococcus granulosus myosin light chain kinase smooth muscle 0.0253 0.1364 0.2728
Loa Loa (eye worm) hypothetical protein 0.0009 0.0011 0.002
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0037 0.0164 1
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0035 0.0154 0.1394
Loa Loa (eye worm) CYP4Cod1 0.0012 0.0025 0.0048
Echinococcus multilocularis protein dispatched 1 0.0075 0.0375 0.0374
Brugia malayi hypothetical protein 0.0034 0.0149 0.0883
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0035 0.0154 0.3403
Onchocerca volvulus Cathepsin L homolog 0.001 0.0013 0.0124
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0023 0.0087 0.0514
Onchocerca volvulus 0.001 0.0013 0.0124
Loa Loa (eye worm) hypothetical protein 0.002 0.0073 0.0144
Leishmania major 4-coumarate:coa ligase-like protein 0.0037 0.0164 0.3444
Schistosoma mansoni hypothetical protein 0.0063 0.0311 0.0459
Brugia malayi Melatonin receptor type 1A 0.007 0.0346 0.205
Loa Loa (eye worm) hhat protein 0.0089 0.0451 0.0902
Mycobacterium tuberculosis Conserved protein 0.0023 0.0088 0.0998
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Brugia malayi LBP / BPI / CETP family, C-terminal domain containing protein 0.002 0.0073 0.043
Toxoplasma gondii thioredoxin reductase 0.0029 0.0119 0.0252
Echinococcus granulosus tm gpcr rhodopsin 0.007 0.0346 0.0691
Schistosoma mansoni atypical protein kinase C 0.0055 0.0266 0.0393
Loa Loa (eye worm) hypothetical protein 0.0051 0.0243 0.0485
Schistosoma mansoni hypothetical protein 0.0029 0.0122 0.018
Onchocerca volvulus 0.0022 0.0079 0.081
Onchocerca volvulus 0.0036 0.0157 0.1623
Echinococcus granulosus rhodopsin orphan GPCR 0.007 0.0346 0.0691
Loa Loa (eye worm) hypothetical protein 0.0036 0.0161 0.032
Brugia malayi protein kinase C II. 0.0008 0.0004 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0023 0.0087 0.0514
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.001 0.0014 0.0021
Trypanosoma brucei PAB1-binding protein , putative 0.0036 0.0161 0.3548
Schistosoma mansoni hypothetical protein 0.0111 0.0573 0.0848
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Loa Loa (eye worm) hypothetical protein 0.0021 0.0076 0.0151
Schistosoma mansoni hypothetical protein 0.0063 0.0311 0.0459
Echinococcus multilocularis g-protein coupled receptor 0.007 0.0346 0.0345
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0023 0.0088 0.052
Loa Loa (eye worm) patched family protein 0.0009 0.0011 0.002
Onchocerca volvulus 0.007 0.0346 0.3595
Loa Loa (eye worm) melatonin receptor type 1A 0.007 0.0346 0.0691
Schistosoma mansoni myelin transcription factor 1 myt1 0.0043 0.0199 0.0294
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.001 0.0015 0.0307
Trichomonas vaginalis glucosylceramidase, putative 0.0142 0.0749 0.6799
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.001 0.0014 0.0285
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0011 0.002 0.0037
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0008 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0028 0.0112 0.0223
Schistosoma mansoni hypothetical protein 0.0217 0.1161 0.172
Plasmodium falciparum plasmepsin III 0.0034 0.0149 0.252
Echinococcus multilocularis g protein coupled receptor 0.007 0.0346 0.0345
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0037 0.0164 1
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0035 0.0154 0.1394
Onchocerca volvulus 0.007 0.0346 0.3595
Plasmodium falciparum ataxin-2 like protein, putative 0.0036 0.0161 0.2718
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0035 0.0154 0.1394
Brugia malayi Patched family protein 0.0009 0.0011 0.0065
Echinococcus granulosus g-protein coupled receptor 0.007 0.0346 0.0691
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Onchocerca volvulus Glucosylceramidase homolog 0.0135 0.0708 0.7363
Brugia malayi hypothetical protein 0.002 0.0071 0.0422
Echinococcus granulosus G protein coupled receptor 139 0.007 0.0346 0.0691
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0014 0.0117
Loa Loa (eye worm) hypothetical protein 0.0023 0.0088 0.0174
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0034 0.0149 0.0297
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0149 0.022
Echinococcus multilocularis neuropeptides capa receptor 0.007 0.0346 0.0345
Schistosoma mansoni microtubule-associated protein tau 0.0396 0.2156 0.3195
Treponema pallidum alginate O-acetylation protein (algI) 0.0089 0.0451 0.7295
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0035 0.0154 0.1394
Loa Loa (eye worm) isocitrate dehydrogenase 0.0013 0.0029 0.0057
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Schistosoma mansoni amine GPCR 0.007 0.0346 0.0512
Brugia malayi Dopamine receptor 0.007 0.0346 0.205
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.001 0.0015 0.0307
Loa Loa (eye worm) hypothetical protein 0.0015 0.0044 0.0086
Schistosoma mansoni hypothetical protein 0.0051 0.0243 0.036
Loa Loa (eye worm) hypothetical protein 0.0009 0.0011 0.002
Brugia malayi Steroid receptor seven-up type 2 0.0095 0.0484 0.2866
Echinococcus granulosus neuropeptides capa receptor 0.007 0.0346 0.0691
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.001 0.0015 0.0307
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0013 0.0108
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.001 0.0014 0.0027
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0089 0.0451 0.0902
Entamoeba histolytica acyl-CoA synthetase, putative 0.0037 0.0164 0.2019
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.001 0.0015 0.0028
Mycobacterium ulcerans flavoprotein disulfide reductase 0.001 0.0015 0.0848
Mycobacterium tuberculosis Conserved protein 0.0023 0.0088 0.0998
Trichomonas vaginalis glucosylceramidase, putative 0.0206 0.1101 1
Loa Loa (eye worm) PDE1B protein 0.001 0.0014 0.0026
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0037 0.0164 0.1987
Brugia malayi Serotonin receptor 0.007 0.0346 0.205
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.001 0.0014 0.0026
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0023 0.0087 0.0172
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.002 0.0071 0.0151
Schistosoma mansoni hypothetical protein 0.0063 0.0311 0.0459
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.007 0.0346 0.0512
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0451 0.4097
Loa Loa (eye worm) hypothetical protein 0.002 0.0071 0.0141
Plasmodium vivax patched family protein, putative 0.0009 0.0011 0.0172
Loa Loa (eye worm) hypothetical protein 0.0011 0.002 0.0037
Loa Loa (eye worm) hypothetical protein 0.002 0.0073 0.0144
Brugia malayi AMP-binding enzyme family protein 0.0037 0.0164 0.097
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0066 0.0323 0.4055
Brugia malayi putative neuropeptide receptor NPR1 0.007 0.0346 0.205
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0011 0.0019 0.0109
Onchocerca volvulus 0.0023 0.0087 0.0895
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Loa Loa (eye worm) hypothetical protein 0.0089 0.0451 0.0902
Toxoplasma gondii hypothetical protein 0.002 0.0071 0.0151
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0011 0.0019 0.0514
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.001 0.0013 0.0108
Echinococcus granulosus g protein coupled receptor 0.007 0.0346 0.0691
Echinococcus multilocularis SAM and MBT domain containing protein 0.0038 0.017 0.0169
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0035 0.0154 0.1394
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0029 0.0123 0.0244
Brugia malayi mbt repeat family protein 0.0038 0.017 0.1008
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0089 0.0451 0.0668
Plasmodium falciparum phosphodiesterase delta, putative 0.001 0.0014 0.0218
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.001 0.0014 0.0013
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.001 0.0014 0.0285
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0149 0.022
Onchocerca volvulus 0.002 0.0071 0.0734
Trichomonas vaginalis penicillin-binding protein, putative 0.0023 0.0088 0.0791
Onchocerca volvulus 0.002 0.0073 0.0747
Brugia malayi Dopamine receptor protein 2 0.007 0.0346 0.205
Echinococcus multilocularis Niemann Pick C1 protein 0.0219 0.1172 0.1172
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0011 0.0019 0.0019
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.001 0.0015 0.002
Brugia malayi hypothetical protein 0.0009 0.0011 0.0065
Plasmodium vivax plasmepsin V, putative 0.0034 0.0149 0.252
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.001 0.0014 0.0117
Toxoplasma gondii hypothetical protein 0.002 0.0071 0.0151
Echinococcus multilocularis musashi 0.0022 0.0079 0.0078
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0029 0.0123 0.018
Leishmania major hypothetical protein, conserved 0.001 0.0014 0.0021
Brugia malayi larval opioid receptor 0.007 0.0346 0.205
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.002 0.0071 0.0105
Loa Loa (eye worm) hypothetical protein 0.0009 0.0011 0.002
Loa Loa (eye worm) hypothetical protein 0.002 0.0073 0.0144
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.1225 0.6746 1
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0035 0.0154 0.3403
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.007 0.0346 0.0691
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.001 0.0014 0.0117
Toxoplasma gondii hypothetical protein 0.0025 0.01 0.0212
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0089 0.0451 0.0963
Schistosoma mansoni neuropeptide F-like receptor 0.007 0.0346 0.0512
Echinococcus multilocularis fmrfamide receptor 0.007 0.0346 0.0345
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.001 0.0014 0.0117
Schistosoma mansoni neuropeptide receptor 0.007 0.0346 0.0512
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0013 0.0029 0.0057
Loa Loa (eye worm) hypothetical protein 0.0009 0.0011 0.002
Brugia malayi hypothetical protein 0.007 0.0346 0.205
Toxoplasma gondii aspartyl protease ASP3 0.0114 0.0589 0.1257
Entamoeba histolytica vacuolar protein sorting 26 0.0089 0.0451 0.5582
Schistosoma mansoni hypothetical protein 0.0063 0.0311 0.0459
Trichomonas vaginalis glucosylceramidase, putative 0.0206 0.1101 1
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0312 0.1689 0.3379
Plasmodium vivax plasmepsin IV, putative 0.0108 0.056 0.9508
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0027 0.0038
Mycobacterium ulcerans lipase LipD 0.0023 0.0088 0.5337
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0027 0.0158
Schistosoma mansoni neuropeptide receptor 0.007 0.0346 0.0512
Loa Loa (eye worm) glutathione reductase 0.0029 0.0119 0.0236
Echinococcus multilocularis neuropeptide s receptor 0.007 0.0346 0.0345
Brugia malayi gonadotropin-releasing hormone receptor 2 0.007 0.0346 0.205
Entamoeba histolytica hypothetical protein 0.0029 0.0118 0.1457
Leishmania major hypothetical protein, conserved 0.0089 0.0451 1
Brugia malayi MBOAT family protein 0.0089 0.0451 0.2673
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Schistosoma mansoni biogenic amine (5HT) receptor 0.007 0.0346 0.0512
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0037 0.0164 0.4497
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0023 0.0087 0.0514
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0013 0.0029 0.0042
Schistosoma mansoni neuropeptide receptor 0.007 0.0346 0.0512
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.001 0.0014 0.0117
Echinococcus granulosus geminin 0.0135 0.0708 0.1416
Echinococcus granulosus rhodopsin orphan GPCR 0.007 0.0346 0.0691
Echinococcus granulosus sodium and chloride dependent glycine 0.002 0.0071 0.0141
Echinococcus granulosus ecdysone induced protein 78C 0.0023 0.0087 0.0172
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.001 0.0014 0.0027
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.007 0.0346 0.0345
Trypanosoma cruzi PAB1-binding protein , putative 0.0036 0.0161 0.3548
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0037
Trichomonas vaginalis glucosylceramidase, putative 0.0142 0.0749 0.6799
Onchocerca volvulus Huntingtin homolog 0.0181 0.0962 1
Loa Loa (eye worm) hypothetical protein 0.0111 0.0573 0.1145
Plasmodium vivax glutathione reductase, putative 0.0029 0.0119 0.2004
Trichomonas vaginalis glucosylceramidase, putative 0.0135 0.0708 0.6432
Onchocerca volvulus 0.0023 0.0088 0.0906
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.007 0.0346 0.0512
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.001 0.0014 0.9291
Brugia malayi nuclear hormone receptor 0.0011 0.002 0.0116
Plasmodium falciparum acyl-CoA synthetase 0.0028 0.0112 0.1893
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0073 0.0363 0.4583
Echinococcus multilocularis G protein coupled receptor 139 0.007 0.0346 0.0345
Echinococcus multilocularis G-protein coupled receptor, putative 0.007 0.0346 0.0345
Trichomonas vaginalis glucosylceramidase, putative 0.0135 0.0708 0.6432
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0108 0.056 0.0829
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Echinococcus granulosus g protein coupled receptor 0.007 0.0346 0.0691
Brugia malayi Hhat protein 0.0089 0.0451 0.2673
Onchocerca volvulus Huntingtin homolog 0.0181 0.0962 1
Loa Loa (eye worm) hypothetical protein 0.0009 0.0011 0.002
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0073 0.0363 0.4583
Brugia malayi AMP-binding enzyme family protein 0.0011 0.0019 0.0115
Brugia malayi Patched family protein 0.0009 0.0011 0.0065
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0037 0.0163 0.3588
Mycobacterium tuberculosis Probable oxidoreductase 0.0073 0.0363 0.4583
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.002 0.0071 0.0071
Entamoeba histolytica cysteine proteinase, putative 0.001 0.0013 0.0148
Mycobacterium ulcerans esterase/lipase LipP 0.0023 0.0088 0.5337
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0043 0.0199 0.0398
Leishmania major acetyl-CoA synthetase, putative 0.0011 0.0019 0.0153
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0008 0.0004 0.0006
Schistosoma mansoni hypothetical protein 0.007 0.0346 0.0512
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0037 0.0163 0.3588
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0013 0.0029 0.0028
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0164 0.1987
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0013 0.0029 0.0631
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Echinococcus multilocularis alpha 1A adrenergic receptor 0.007 0.0346 0.0345
Plasmodium falciparum plasmepsin II 0.0108 0.056 0.9508
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Echinococcus multilocularis neuropeptide Y receptor 0.007 0.0346 0.0345
Loa Loa (eye worm) hypothetical protein 0.0028 0.0112 0.0223
Echinococcus granulosus rhodopsin orphan GPCR 0.007 0.0346 0.0691
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.007 0.0346 0.0345
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.007 0.0346 0.0345
Loa Loa (eye worm) hypothetical protein 0.0011 0.002 0.0037
Loa Loa (eye worm) hypothetical protein 0.0009 0.0011 0.002
Brugia malayi glutathione reductase 0.0029 0.0119 0.0703
Onchocerca volvulus 0.0023 0.0088 0.0906
Echinococcus granulosus beta LACTamase domain containing family member 0.0023 0.0088 0.0174
Loa Loa (eye worm) LBP/BPI/CETP family domain-containing protein 0.002 0.0073 0.0144
Brugia malayi Patched family protein 0.0009 0.0011 0.0065
Loa Loa (eye worm) cytochrome P450 family protein 0.003 0.0124 0.0246
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.0104 0.1206
Loa Loa (eye worm) G-protein coupled receptor 0.007 0.0346 0.0691
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0035 0.0154 0.0913
Giardia lamblia Hypothetical protein 0.001 0.0014 0.9291
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0011 0.0019 0.1144
Trypanosoma cruzi cysteine peptidase, putative 0.001 0.0013 0.0265
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0023 0.0087 0.0895
Loa Loa (eye worm) hypothetical protein 0.0119 0.0619 0.1237
Onchocerca volvulus 0.001 0.0013 0.0124
Loa Loa (eye worm) hypothetical protein 0.0037 0.0164 0.0326
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.01 0.0901
Loa Loa (eye worm) hypothetical protein 0.002 0.0073 0.0144
Brugia malayi hypothetical protein 0.007 0.0346 0.205
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.007 0.0346 0.0345
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.001 0.0014 0.0027
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0023 0.0087 0.0514
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0023 0.0087 0.0127
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0095 0.0484 0.0483
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.001 0.0014 0.0117
Brugia malayi conserved hypotetical protein 0.0011 0.002 0.0116
Brugia malayi protein C24B5.3 0.0009 0.0011 0.0065
Toxoplasma gondii isocitrate dehydrogenase 0.0013 0.0029 0.0061
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0013 0.0029 0.0028
Mycobacterium ulcerans acyl-CoA synthetase 0.0011 0.0019 0.1144
Brugia malayi nuclear receptor RXR 0.0012 0.0027 0.0158
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0011 0.0019 0.0231
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Loa Loa (eye worm) MBOAT family protein 0.0089 0.0451 0.0902
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0011 0.0019 0.004
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.001 0.0014 0.0013
Loa Loa (eye worm) hypothetical protein 0.0009 0.0011 0.002
Mycobacterium ulcerans acyl-CoA synthetase 0.0011 0.0019 0.1144
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0312 0.1689 1
Schistosoma mansoni sodium/chloride dependent transporter 0.0119 0.0619 0.0916
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0023 0.0087 0.0514
Onchocerca volvulus 0.001 0.0013 0.0124
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.001 0.0013 0.0108
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.001 0.0015 0.1242
Onchocerca volvulus Neuropeptide F receptor homolog 0.007 0.0346 0.3595
Brugia malayi topoisomerase 0.0007 0.0001 0.0005
Brugia malayi protein kinase C3,putative 0.0048 0.0223 0.1321
Schistosoma mansoni RAR-like nuclear receptor 0.0023 0.0087 0.0127
Echinococcus multilocularis neuropeptide receptor A26 0.007 0.0346 0.0345
Schistosoma mansoni myosin xvIII 0.007 0.0346 0.0512
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0089 0.0451 0.0902
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0023 0.0087 0.0127
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0037 0.0163 0.3588
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0164 1
Trichomonas vaginalis glucosylceramidase, putative 0.0206 0.1101 1
Loa Loa (eye worm) hypothetical protein 0.0009 0.0011 0.002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.007 0.0346 0.0512
Echinococcus multilocularis sterol regulatory element binding protein 0.0066 0.0324 0.0323
Schistosoma mansoni steroid hormone receptor ad4bp 0.0023 0.0087 0.0127
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0312 0.1689 0.1688
Leishmania major glycerol uptake protein, putative 0.0089 0.0451 1
Brugia malayi G protein-coupled receptor F59B2.13 0.007 0.0346 0.205
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0013 0.0108
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0013 0.0029 0.0236
Echinococcus granulosus X box binding protein 1 0.023 0.1233 0.2466
Onchocerca volvulus 0.007 0.0346 0.3595
Giardia lamblia NADH oxidase lateral transfer candidate 0.001 0.0015 1
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0011 0.0019 0.0109
Brugia malayi MBOAT family protein 0.0089 0.0451 0.2673
Schistosoma mansoni rhodopsin-like orphan GPCR 0.007 0.0346 0.0512
Echinococcus multilocularis FTZ F1 alpha 0.0023 0.0087 0.0086
Echinococcus granulosus allatostatin A receptor 0.007 0.0346 0.0691
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.001 0.0015 0.0235
Loa Loa (eye worm) hypothetical protein 0.0009 0.0011 0.002
Onchocerca volvulus 0.0011 0.0019 0.0194
Echinococcus granulosus rhodopsin orphan GPCR 0.007 0.0346 0.0691
Brugia malayi hypothetical protein 0.0007 0.0001 0.0005
Mycobacterium tuberculosis Probable lipase LipE 0.0023 0.0088 0.0998
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0035 0.0154 0.1394
Onchocerca volvulus Protein patched homolog 0.0009 0.0011 0.0105
Onchocerca volvulus 0.0009 0.0011 0.0105
Plasmodium falciparum plasmepsin V 0.0034 0.0149 0.252
Loa Loa (eye worm) hypothetical protein 0.0023 0.0087 0.0172
Loa Loa (eye worm) patched family protein 0.0009 0.0011 0.002
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0153 0.0808 1
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.007 0.0346 0.0512
Plasmodium falciparum lipid/sterol:H+ symporter 0.0009 0.0011 0.0172
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0014 0.0285
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0016 0.005 0.0098
Brugia malayi CHE-14 protein 0.0066 0.0324 0.1917
Echinococcus multilocularis protein kinase c iota type 0.0052 0.0248 0.0247
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0035 0.0154 0.1394
Echinococcus granulosus Nuclear hormone receptor HR96 0.0011 0.002 0.0037
Loa Loa (eye worm) hypothetical protein 0.0009 0.0011 0.002
Echinococcus multilocularis serotonin transporter 0.0119 0.0619 0.0618
Echinococcus multilocularis dnaJ subfamily B 0.0217 0.1161 0.116
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0023 0.0087 0.0172
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.01 0.0901
Trichomonas vaginalis glucosylceramidase, putative 0.0135 0.0708 0.6432
Loa Loa (eye worm) intermediate filament protein 0.0022 0.0079 0.0156
Brugia malayi Patched family protein 0.0009 0.0011 0.0065
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.001 0.0014 0.0026
Schistosoma mansoni thyroid hormone receptor 0.0023 0.0087 0.0127
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0035 0.0154 0.0153
Loa Loa (eye worm) hypothetical protein 0.0023 0.0088 0.0174
Echinococcus multilocularis dro:myosuppressin receptor 0.007 0.0346 0.0345
Onchocerca volvulus 0.007 0.0346 0.3595
Leishmania major acetyl-CoA synthetase, putative 0.0011 0.0019 0.0153
Echinococcus granulosus sterol regulatory element binding protein 0.0066 0.0324 0.0646
Loa Loa (eye worm) hypothetical protein 0.0028 0.0112 0.0223
Echinococcus granulosus Niemann Pick C1 protein 0.0219 0.1172 0.2345
Onchocerca volvulus Protein patched homolog 0.0009 0.0011 0.0105
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.002 0.0071 0.0105
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0026
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0011 0.0019 0.0109
Echinococcus multilocularis neuropeptide receptor 0.007 0.0346 0.0345
Schistosoma mansoni rhodopsin-like orphan GPCR 0.007 0.0346 0.0512
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.001 0.0014 0.0285
Schistosoma mansoni thyroid hormone receptor 0.0023 0.0087 0.0127
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0023 0.0087 0.0086
Loa Loa (eye worm) hypothetical protein 0.0023 0.0087 0.0172
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.002 0.0071 0.0071
Echinococcus granulosus o acyltransferase membrane bound domain 0.0089 0.0451 0.0902
Echinococcus granulosus cytoplasmic intermediate filament protein 0.001 0.0017 0.0032
Brugia malayi Cytochrome P450 family protein 0.0012 0.0025 0.0146
Loa Loa (eye worm) hypothetical protein 0.0009 0.0011 0.002
Brugia malayi Patched family protein 0.0009 0.0011 0.0065
Echinococcus granulosus tachykinin peptides receptor 99D 0.007 0.0346 0.0691
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.001 0.0014 0.0027
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0149 0.022
Brugia malayi hypothetical protein 0.007 0.0346 0.205
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0016 0.005 0.0049
Echinococcus multilocularis rhodopsin orphan GPCR 0.007 0.0346 0.0345
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0089 0.0451 0.0451
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0119 0.0619 0.0916
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0023 0.0087 0.0127
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.001 0.0014 0.0019
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0164 1
Toxoplasma gondii aspartyl protease 0.0034 0.0149 0.0317
Entamoeba histolytica hypothetical protein, conserved 0.0089 0.0451 0.5582
Brugia malayi Patched family protein 0.0009 0.0011 0.0065
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0012 0.0025 0.1466
Onchocerca volvulus 0.0037 0.0164 0.1697
Brugia malayi LBP / BPI / CETP family, N-terminal domain containing protein 0.0036 0.0157 0.0928
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0012 0.0027 0.0052
Loa Loa (eye worm) hypothetical protein 0.002 0.0073 0.0144
Onchocerca volvulus 0.007 0.0346 0.3595
Brugia malayi nuclear receptor NHR-67 0.0011 0.002 0.0116
Onchocerca volvulus 0.007 0.0346 0.3595
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0011 0.0019 0.0109
Toxoplasma gondii aspartyl protease ASP1 0.0108 0.056 0.1195
Brugia malayi AKH receptor 0.007 0.0346 0.205
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.001 0.0015 0.0014
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.007 0.0346 0.0512
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0038 0.017 0.1763
Schistosoma mansoni hypothetical protein 0.0231 0.1241 0.1838
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0023 0.0087 0.0514
Loa Loa (eye worm) hypothetical protein 0.0015 0.0044 0.0086
Loa Loa (eye worm) hhat protein 0.0089 0.0451 0.0902
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0035 0.0154 0.1394
Loa Loa (eye worm) DR-78 0.0011 0.002 0.0037
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0035 0.0154 0.1394
Brugia malayi hypothetical protein 0.0012 0.0027 0.0158
Brugia malayi MBOAT family protein 0.0089 0.0451 0.2673
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.001 0.0014 0.0019
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0011 0.0019 0.0414
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.007 0.0346 0.0512
Trichomonas vaginalis antibiotic synthetase, putative 0.0011 0.0019 0.0169
Mycobacterium ulcerans hypothetical protein 0.0037 0.0164 1
Brugia malayi protein C24B5.3 0.0009 0.0011 0.0065
Brugia malayi hypothetical protein 0.0144 0.0756 0.4476
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.001 0.0014 0.0117
Trypanosoma cruzi cysteine peptidase, putative 0.0037 0.0163 0.3588
Echinococcus multilocularis lamin 0.0022 0.0079 0.0078
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.002 0.0071 0.0141
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.001 0.0014 0.0027
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.001 0.0014 0.0026
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0089 0.0451 0.0902
Echinococcus granulosus polycomb protein SCMH1 0.0038 0.017 0.0339
Echinococcus multilocularis expressed conserved protein 0.0144 0.0757 0.0756
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.001 0.0013 0.0108
Brugia malayi putative neuropeptide receptor 0.007 0.0346 0.205
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.001 0.0014 0.0013
Onchocerca volvulus 0.001 0.0013 0.0124
Echinococcus multilocularis cathepsin l cysteine peptidase 0.001 0.0013 0.0012
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.002 0.0071 0.0151
Trichomonas vaginalis glucosylceramidase, putative 0.0206 0.1101 1
Onchocerca volvulus 0.001 0.0013 0.0124
Brugia malayi cytoplasmic intermediate filament protein 0.0012 0.0023 0.0138
Schistosoma mansoni biogenic amine (dopamine) receptor 0.007 0.0346 0.0512
Echinococcus multilocularis polycomb protein SCMH1 0.0038 0.017 0.0169
Echinococcus multilocularis rhodopsin orphan GPCR 0.007 0.0346 0.0345
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.001 0.0014 0.0218
Echinococcus granulosus microtubule associated protein 2 0.0396 0.2156 0.4314
Loa Loa (eye worm) patched family protein 0.0009 0.0011 0.002
Echinococcus multilocularis biogenic amine (5HT) receptor 0.007 0.0346 0.0345
Loa Loa (eye worm) cysteine protease 0.001 0.0013 0.0024
Trichomonas vaginalis antibiotic synthetase, putative 0.0011 0.0019 0.0169
Loa Loa (eye worm) hypothetical protein 0.0119 0.0619 0.1237
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.001 0.0014 0.0027
Loa Loa (eye worm) hypothetical protein 0.0162 0.0857 0.1713
Plasmodium vivax aspartyl protease, putative 0.0114 0.0589 1
Echinococcus granulosus survival motor neuron protein 1 0.0144 0.0756 0.1511
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0451 0.4097
Brugia malayi hypothetical protein 0.007 0.0346 0.205
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0037 0.0163 0.3588
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0011 0.0019 0.1144
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0023 0.0087 0.0514
Plasmodium falciparum cGMP-specific phosphodiesterase 0.001 0.0014 0.0218
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.002 0.0037
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0034 0.0149 0.0317
Treponema pallidum sodium- and chloride- dependent transporter 0.0119 0.0619 1
Plasmodium falciparum cysteine proteinase falcipain 3 0.001 0.0013 0.0203
Trichomonas vaginalis glucosylceramidase, putative 0.0135 0.0708 0.6432
Brugia malayi aspartic protease BmAsp-2, identical 0.0034 0.0149 0.0883
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.007 0.0346 0.0691
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.007 0.0346 0.0691
Entamoeba histolytica cysteine protease, putative 0.001 0.0013 0.0148
Schistosoma mansoni rhodopsin-like orphan GPCR 0.007 0.0346 0.0512
Schistosoma mansoni transcription factor LCR-F1 0.0029 0.0118 0.0174
Schistosoma mansoni sex comb on midleg homolog 0.0038 0.017 0.0251
Brugia malayi Patched related family protein 10 0.0009 0.0011 0.0065
Brugia malayi diacylglycerol acyltransferase 0.0089 0.0451 0.2673
Brugia malayi hypothetical protein 0.0009 0.0011 0.0065
Brugia malayi photoreceptor-specific nuclear receptor 0.0023 0.0087 0.0514
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.001 0.0014 0.0027
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0035 0.0154 0.1394
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.001 0.0015 1
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.002 0.0071 0.0105
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.007 0.0346 0.0345
Loa Loa (eye worm) LBP/BPI/CETP family domain-containing protein 0.002 0.0073 0.0144
Giardia lamblia hypothetical protein 0.001 0.0014 0.9291
Brugia malayi nuclear receptor NHR-88 0.0011 0.002 0.0116
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0035 0.0154 0.1394
Echinococcus granulosus serotonin transporter 0.0119 0.0619 0.1237
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.015 0.079 0.0789
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.001 0.0014 0.0026
Echinococcus granulosus biogenic amine 5HT receptor 0.007 0.0346 0.0691
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.001 0.0013 0.0024
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0007 0.0001 0.0000042635
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.007 0.0346 0.205
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.001 0.0014 0.0285
Mycobacterium tuberculosis Probable esterase LipL 0.0023 0.0088 0.0998
Plasmodium falciparum amino acid transporter, putative 0.002 0.0071 0.1199
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0023 0.0088 0.0174
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0023 0.0087 0.0172
Toxoplasma gondii propionate-CoA ligase 0.0011 0.0019 0.004
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0089 0.0451 0.0902
Toxoplasma gondii patched family protein 0.0009 0.0011 0.0022
Loa Loa (eye worm) hypothetical protein 0.0009 0.0011 0.002
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0029 0.0119 0.14
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0007 0.0001 0.0000031297
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0014 0.0285
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0023 0.0087 0.0172
Plasmodium falciparum transporter, putative 0.002 0.0071 0.1199
Echinococcus multilocularis geminin 0.0135 0.0708 0.0707
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0035 0.0154 0.3403
Loa Loa (eye worm) norepinephrine transporter 0.0119 0.0619 0.1237
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0024
Brugia malayi Patched family protein 0.0009 0.0011 0.0065
Brugia malayi Intermediate filament tail domain containing protein 0.0022 0.0079 0.0466
Loa Loa (eye worm) neuropeptide F receptor 0.007 0.0346 0.0691
Schistosoma mansoni nuclear receptor 0.0011 0.002 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0013 0.0108
Loa Loa (eye worm) hypothetical protein 0.0043 0.0199 0.0398
Schistosoma mansoni zinc finger protein 0.0089 0.0451 0.0668
Echinococcus multilocularis rhodopsin orphan GPCR 0.007 0.0346 0.0345
Brugia malayi Patched family protein 0.0009 0.0011 0.0065
Loa Loa (eye worm) hypothetical protein 0.0011 0.002 0.0037
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0013 0.0108
Brugia malayi Patched family protein 0.0009 0.0011 0.0065
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0051 0.0243 0.1441
Loa Loa (eye worm) follicle stimulating hormone receptor 0.007 0.0346 0.0691
Loa Loa (eye worm) hypothetical protein 0.0009 0.0011 0.002
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.001 0.0015 0.0307
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0013 0.0108
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0051 0.0243 0.0485
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0052
Onchocerca volvulus 0.0011 0.0019 0.0194
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0013 0.0029 0.0631
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0011 0.0019 0.0115
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0013 0.0029 0.0377
Brugia malayi nuclear hormone receptor family member odr-7 0.0011 0.002 0.0116
Echinococcus granulosus uncharacterized sodium dependent transporter 0.002 0.0071 0.0141
Trypanosoma cruzi trypanothione reductase, putative 0.001 0.0015 0.0307
Echinococcus multilocularis serotonin receptor 0.007 0.0346 0.0345
Brugia malayi hypothetical protein 0.007 0.0346 0.205
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.001 0.0015 0.0307
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0025 0.01 0.1156
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.001 0.0015 0.0307
Loa Loa (eye worm) hypothetical protein 0.0089 0.0451 0.0902
Schistosoma mansoni hypothetical protein 0.007 0.0346 0.0512
Echinococcus granulosus nuclear receptor nhr 48 0.0011 0.002 0.0037
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0011 0.0019 0.0109
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0066 0.0323 0.4055
Echinococcus granulosus serotonin receptor 0.007 0.0346 0.0691
Echinococcus granulosus lamin 0.0022 0.0079 0.0156
Loa Loa (eye worm) hypothetical protein 0.0089 0.0451 0.0902
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0013 0.0029 0.0484
Echinococcus granulosus dnaJ subfamily B 0.0217 0.1161 0.2321
Onchocerca volvulus 0.0034 0.0149 0.1543
Loa Loa (eye worm) hypothetical protein 0.0009 0.0011 0.002
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0012 0.0027 0.0026
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0037 0.0163 0.3588
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0044 0.0389
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0011 0.002 0.0028
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.007 0.0346 0.0512
Schistosoma mansoni cathepsin F (C01 family) 0.001 0.0013 0.0018
Plasmodium falciparum plasmepsin I 0.0108 0.056 0.9508
Brugia malayi hypothetical protein 0.007 0.0346 0.205
Loa Loa (eye worm) hypothetical protein 0.0023 0.0088 0.0174
Loa Loa (eye worm) papain family cysteine protease containing protein 0.001 0.0013 0.0024
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0011 0.002 0.0195
Brugia malayi hypothetical protein 0.007 0.0346 0.205
Loa Loa (eye worm) G-protein coupled receptor 0.007 0.0346 0.0691
Brugia malayi steroid hormone receptor 0.0023 0.0087 0.0514
Trypanosoma brucei cytochrome P450, putative 0.0012 0.0025 0.053
Schistosoma mansoni opsin-like receptor 0.007 0.0346 0.0512
Brugia malayi neuropeptide F receptor 0.007 0.0346 0.205
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0011 0.0019 0.1144
Schistosoma mansoni nuclear receptor 0.0011 0.002 0.0028
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0052
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0011 0.002 0.0116
Schistosoma mansoni serine/threonine protein kinase 0.0008 0.0004 0.0005
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0013 0.0029 0.0631
Toxoplasma gondii hypothetical protein 0.0025 0.01 0.0212
Loa Loa (eye worm) hypothetical protein 0.0009 0.0011 0.002
Loa Loa (eye worm) hypothetical protein 0.0153 0.0808 0.1616
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0035 0.0154 0.1394
Plasmodium falciparum plasmepsin X 0.0114 0.0589 1
Trypanosoma cruzi cytochrome P450, putative 0.0012 0.0025 0.053
Brugia malayi G-protein coupled receptor 0.007 0.0346 0.205
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0011 0.0019 0.0037
Toxoplasma gondii isocitrate dehydrogenase 0.0013 0.0029 0.0061
Loa Loa (eye worm) hypothetical protein 0.0108 0.056 0.112
Trypanosoma brucei hypothetical protein, conserved 0.001 0.0014 0.0285
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0029 0.0123 0.0122
Brugia malayi Pepsin A precursor 0.0034 0.0149 0.0883
Loa Loa (eye worm) hypothetical protein 0.0022 0.0079 0.0156
Echinococcus granulosus thyroid hormone receptor alpha 0.0011 0.002 0.0037
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0037 0.0164 1
Echinococcus granulosus FTZ F1 alpha 0.0023 0.0087 0.0172
Schistosoma mansoni neuropeptide f receptor 76f 0.007 0.0346 0.0512
Echinococcus multilocularis somatostatin receptor 0.007 0.0346 0.0345
Loa Loa (eye worm) cytochrome P450 family protein 0.0012 0.0025 0.0048
Echinococcus granulosus 7tm_1 domain containing protein 0.007 0.0346 0.0691
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0011 0.0019 0.0414
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.007 0.0346 0.0512
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0088 0.1479
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0162 0.0857 0.1713
Mycobacterium tuberculosis Probable dehydrogenase 0.0066 0.0323 0.4055
Brugia malayi Thioredoxin reductase 0.0029 0.0119 0.0703
Plasmodium falciparum phosphodiesterase gamma, putative 0.001 0.0014 0.0218
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.001 0.0014 0.0117
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0023 0.0087 0.0514
Echinococcus multilocularis rhodopsin orphan GPCR 0.007 0.0346 0.0345
Toxoplasma gondii GAF domain-containing protein 0.0025 0.01 0.0212
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.007 0.0346 0.205
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0023 0.0088 0.0129
Schistosoma mansoni amine GPCR 0.007 0.0346 0.0512
Loa Loa (eye worm) hypothetical protein 0.0011 0.002 0.0037
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0035 0.0154 0.1394
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0035 0.0154 0.1394
Trichomonas vaginalis mercuric reductase, putative 0.001 0.0015 0.0126
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0023 0.0087 0.0127
Brugia malayi Cathepsin L-like precursor 0.001 0.0013 0.0076
Trichomonas vaginalis glucosylceramidase, putative 0.0206 0.1101 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.0011 0.002 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.01 0.0901
Onchocerca volvulus 0.0009 0.0011 0.0105
Brugia malayi hypothetical protein 0.0009 0.0011 0.0065
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.002 0.0071 0.0105
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Echinococcus multilocularis g protein coupled receptor 0.007 0.0346 0.0345
Mycobacterium ulcerans acyl-CoA synthetase 0.0011 0.0019 0.1144
Plasmodium falciparum plasmepsin VIII, putative 0.0034 0.0149 0.252
Mycobacterium ulcerans acyl-CoA synthetase 0.0011 0.0019 0.1144
Echinococcus multilocularis rhodopsin orphan GPCR 0.007 0.0346 0.0345
Echinococcus granulosus alpha 1A adrenergic receptor 0.007 0.0346 0.0691
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Leishmania major hypothetical protein, conserved 0.0036 0.0161 0.3373
Schistosoma mansoni cathepsin D (A01 family) 0.039 0.2123 0.3146
Loa Loa (eye worm) hypothetical protein 0.002 0.0071 0.0141
Schistosoma mansoni amine GPCR 0.007 0.0346 0.0512
Mycobacterium ulcerans acetyl-CoA synthetase 0.0011 0.0019 0.1144
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0035 0.0154 0.1394
Mycobacterium ulcerans putative regulatory protein 0.0025 0.01 0.6081
Mycobacterium tuberculosis Probable lipase LipD 0.0023 0.0088 0.0998
Schistosoma mansoni hypothetical protein 0.023 0.1233 0.1826
Echinococcus granulosus tm gpcr rhodopsin 0.007 0.0346 0.0691
Loa Loa (eye worm) hypothetical protein 0.0015 0.0044 0.0086
Loa Loa (eye worm) hypothetical protein 0.0009 0.0011 0.002
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.001 0.0014 0.0019
Brugia malayi Serotonin/octopamine receptor family protein 7 0.007 0.0346 0.205
Plasmodium falciparum GAF domain-related protein, putative 0.0025 0.01 0.1685
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Loa Loa (eye worm) hypothetical protein 0.0009 0.0011 0.002
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0089 0.0451 0.0963
Leishmania major 4-coumarate:coa ligase-like protein 0.0037 0.0164 0.3444
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Onchocerca volvulus 0.0036 0.0157 0.1623
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Entamoeba histolytica acyl-coA synthetase, putative 0.0037 0.0164 0.2019
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0011 0.0019 0.0115
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0032
Toxoplasma gondii LsmAD domain-containing protein 0.0036 0.0161 0.0342
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0029 0.0123 0.018
Schistosoma mansoni hypothetical protein 0.0135 0.0708 0.1049
Trypanosoma brucei glycerol uptake protein, putative 0.0089 0.0451 1
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.001 0.0014 0.0218
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0011 0.0019 0.1144
Echinococcus granulosus neuropeptide receptor 0.007 0.0346 0.0691
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0088 0.1931
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0089 0.0451 0.0451
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0037 0.0163 0.3588
Brugia malayi LBP / BPI / CETP family, C-terminal domain containing protein 0.002 0.0073 0.043
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.001 0.0014 0.0027
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0066 0.0323 0.4055
Loa Loa (eye worm) hypothetical protein 0.0009 0.0011 0.002
Echinococcus granulosus biogenic amine 5HT receptor 0.007 0.0346 0.0691
Loa Loa (eye worm) hypothetical protein 0.0028 0.0112 0.0223
Onchocerca volvulus 0.0009 0.0011 0.0105
Loa Loa (eye worm) hypothetical protein 0.0009 0.0011 0.002
Brugia malayi GnHR receptor homolog 0.007 0.0346 0.205
Schistosoma mansoni rhodopsin-like orphan GPCR 0.007 0.0346 0.0512
Loa Loa (eye worm) MBCTL1 0.0043 0.0199 0.0398
Brugia malayi Patched family protein 0.0009 0.0011 0.0065
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0013 0.0108
Echinococcus granulosus cathepsin l1 0.001 0.0013 0.0024
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0029 0.0123 0.0244
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0108 0.056 0.112
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.001 0.0013 0.0108
Echinococcus granulosus neuropeptide s receptor 0.007 0.0346 0.0691
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.002 0.0071 0.0105
Onchocerca volvulus 0.007 0.0346 0.3595
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Brugia malayi nuclear hormone receptor 0.0023 0.0087 0.0514
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0023 0.0088 0.0129
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.001 0.0014 0.0285
Brugia malayi Patched family protein 0.0009 0.0011 0.0065
Schistosoma mansoni adenoreceptor 0.007 0.0346 0.0512
Brugia malayi AMP-binding enzyme family protein 0.0037 0.0164 0.097
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0035 0.0154 0.1394
Loa Loa (eye worm) hypothetical protein 0.0009 0.0011 0.002
Brugia malayi Patched family protein 0.0009 0.0011 0.0065
Loa Loa (eye worm) hypothetical protein 0.0011 0.002 0.0037
Echinococcus multilocularis neuropeptide receptor 0.007 0.0346 0.0345
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0223 0.1193 0.1768
Plasmodium vivax aspartyl protease, putative 0.0114 0.0589 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0162 0.0857 0.5073
Leishmania major dihydrolipoamide dehydrogenase, putative 0.001 0.0015 0.0043
Toxoplasma gondii patched family protein 0.0009 0.0011 0.0022
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0011 0.002 0.0019
Plasmodium vivax ataxin-2 like protein, putative 0.0036 0.0161 0.2718
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0011 0.0019 0.0037
Schistosoma mansoni nuclear hormone receptor 0.0011 0.002 0.0028
Loa Loa (eye worm) hypothetical protein 0.0023 0.0087 0.0172
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0149 0.022
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0012 0.0026 0.0054
Mycobacterium ulcerans acyl-CoA synthetase 0.0011 0.0019 0.1144
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0154 0.1394
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.001 0.0015 0.0087
Loa Loa (eye worm) hypothetical protein 0.0034 0.0149 0.0297
Echinococcus granulosus dro:myosuppressin receptor 0.007 0.0346 0.0691
Onchocerca volvulus 0.0015 0.0044 0.0446
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0089 0.0451 0.5582
Loa Loa (eye worm) hypothetical protein 0.0009 0.0011 0.002
Toxoplasma gondii NADPH-glutathione reductase 0.001 0.0015 0.003
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.001 0.0014 0.0218
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.001 0.0014 0.0026
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0023 0.0087 0.0172
Onchocerca volvulus 0.0089 0.0451 0.469
Echinococcus granulosus hypothetical protein 0.007 0.0346 0.0691
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.001 0.0015 0.0848
Onchocerca volvulus 0.0036 0.0157 0.1623
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.007 0.0346 0.0512
Entamoeba histolytica hypothetical protein 0.0029 0.0118 0.1457
Entamoeba histolytica hypothetical protein 0.0029 0.0118 0.1457
Mycobacterium tuberculosis Conserved protein 0.0023 0.0088 0.0998
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0011 0.0019 0.0514
Loa Loa (eye worm) hypothetical protein 0.0037 0.0164 0.0326
Loa Loa (eye worm) hypothetical protein 0.0011 0.002 0.0037
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0011 0.0019 0.0514
Plasmodium vivax acyl-CoA synthetase, putative 0.0028 0.0112 0.1893
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0014 0.0285
Brugia malayi Patched family protein 0.0009 0.0011 0.0065
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0035 0.0154 0.1394
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Toxoplasma gondii hypothetical protein 0.0009 0.0011 0.0022
Onchocerca volvulus 0.0036 0.0157 0.1623
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.001 0.0015 0.0307
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.001 0.0015 0.0848
Plasmodium falciparum thioredoxin reductase 0.001 0.0015 0.0235
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0023 0.0087 0.0127
Schistosoma mansoni rhodopsin-like orphan GPCR 0.007 0.0346 0.0512
Schistosoma mansoni amine GPCR 0.007 0.0346 0.0512
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.001 0.0014 0.0285
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.007 0.0346 0.0345
Onchocerca volvulus 0.0036 0.0157 0.1623
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0013 0.0029 0.0631
Brugia malayi aspartic protease BmAsp-1, identical 0.0034 0.0149 0.0883
Onchocerca volvulus 0.007 0.0346 0.3595
Leishmania major cAMP-specific phosphodiesterase, putative 0.001 0.0014 0.0021
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0011 0.002 0.0037
Brugia malayi Pax transcription activation domain interacting protein 0.0007 0.0001 0.0005
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0011 0.0019 0.0109
Brugia malayi Patched related family protein 4 0.0009 0.0011 0.0065
Mycobacterium ulcerans acyl-CoA synthetase 0.0011 0.0019 0.1144
Loa Loa (eye worm) hypothetical protein 0.0009 0.0011 0.002
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0051 0.0243 0.0243
Echinococcus granulosus rhodopsin orphan GPCR 0.007 0.0346 0.0691
Echinococcus granulosus cathepsin l cysteine peptidase 0.001 0.0013 0.0024
Schistosoma mansoni biogenic amine receptor 0.007 0.0346 0.0512
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Brugia malayi Serotonin receptor 0.007 0.0346 0.205
Loa Loa (eye worm) hypothetical protein 0.0009 0.0011 0.002
Trichomonas vaginalis D-aminoacylase, putative 0.0023 0.0088 0.0791
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0011 0.0019 0.0414
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0035 0.0154 0.1394
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0012 0.0023 0.0045
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.007 0.0346 0.0345
Schistosoma mansoni biogenic amine (dopamine) receptor 0.007 0.0346 0.0512
Loa Loa (eye worm) hypothetical protein 0.0028 0.0112 0.0223
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0029 0.0123 0.0244
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0013 0.0029 0.0484
Schistosoma mansoni sodium/chloride dependent transporter 0.0021 0.0073 0.0107
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.001 0.0014 0.0027
Brugia malayi Niemann-Pick C1 protein precursor 0.0153 0.0808 0.4786
Loa Loa (eye worm) TYRA-2 protein 0.007 0.0346 0.0691
Onchocerca volvulus 0.007 0.0346 0.3595
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0089 0.0451 0.0668
Loa Loa (eye worm) hypothetical protein 0.001 0.0015 0.0028
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0023 0.0088 0.0998
Echinococcus granulosus neuropeptide receptor A26 0.007 0.0346 0.0691
Toxoplasma gondii 1,3-beta-glucan synthase component protein 0.0852 0.4681 1
Brugia malayi Eukaryotic aspartyl protease family protein 0.0034 0.0149 0.0883
Echinococcus granulosus neuropeptides capa receptor 0.007 0.0346 0.0691
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0035 0.0154 0.1394
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0035 0.0154 0.1394
Brugia malayi hypothetical protein 0.0034 0.0149 0.0883
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0023 0.0087 0.0172
Echinococcus granulosus 7TM GPCR rhodopsin 0.007 0.0346 0.0691
Loa Loa (eye worm) transcription factor SMAD2 0.0095 0.0487 0.0973
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Echinococcus multilocularis survival motor neuron protein 1 0.0144 0.0756 0.0755
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0089 0.0451 0.766
Schistosoma mansoni cathepsin F (C01 family) 0.001 0.0013 0.0018
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.001 0.0014 0.0027
Brugia malayi MBOAT family protein 0.0089 0.0451 0.2673
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0023 0.0087 0.0172
Brugia malayi hypothetical protein 0.007 0.0346 0.205
Loa Loa (eye worm) hypothetical protein 0.082 0.4505 0.9015
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0035 0.0154 0.3403
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0025 0.01 0.6081
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.002 0.0071 0.6334
Brugia malayi nuclear receptor NHR-88 0.0023 0.0087 0.0514
Leishmania major cathepsin L-like protease 0.0037 0.0163 0.3414
Loa Loa (eye worm) hypothetical protein 0.002 0.0071 0.0141
Echinococcus granulosus tm gpcr rhodopsin 0.007 0.0346 0.0691
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.001 0.0014 0.0081
Echinococcus granulosus neuropeptide Y receptor 0.007 0.0346 0.0691
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0035 0.0154 0.1394
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.001 0.0014 0.0027
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.0104 0.1206
Loa Loa (eye worm) MBOAT family protein 0.0089 0.0451 0.0902
Trichomonas vaginalis porcupine, putative 0.0089 0.0451 0.4097
Echinococcus granulosus rhodopsin orphan GPCR 0.007 0.0346 0.0691
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0089 0.0451 0.0451
Onchocerca volvulus 0.0009 0.0011 0.0105
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0029 0.0123 0.018
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0029 0.0123 0.0122
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.001 0.0015 0.0307
Schistosoma mansoni alpha-1 adrenergic receptor 0.007 0.0346 0.0512
Brugia malayi Papain family cysteine protease containing protein 0.001 0.0013 0.0076
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0051 0.0241 0.0481
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0011 0.0019 0.1144
Schistosoma mansoni rhodopsin-like orphan GPCR 0.007 0.0346 0.0512
Trypanosoma cruzi PAB1-binding protein , putative 0.0036 0.0161 0.3548
Onchocerca volvulus 0.002 0.0071 0.0734
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Plasmodium vivax acetyl-CoA synthetase, putative 0.0011 0.0019 0.0317
Loa Loa (eye worm) hypothetical protein 0.0011 0.002 0.0037
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0087 0.0514
Loa Loa (eye worm) MBOAT family protein 0.0089 0.0451 0.0902
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0023 0.0087 0.0514
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.001 0.0014 0.0081
Echinococcus multilocularis thyroid hormone receptor alpha 0.0023 0.0087 0.0086
Echinococcus multilocularis serine:threonine protein kinase 0.0253 0.1364 0.1363
Schistosoma mansoni histamine h1 receptor 0.007 0.0346 0.0512
Loa Loa (eye worm) hypothetical protein 0.002 0.0071 0.0141
Schistosoma mansoni hypothetical protein 0.0016 0.005 0.0072
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0011 0.0019 0.0109
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0108 0.056 0.5086
Echinococcus multilocularis beta LACTamase domain containing family member 0.0023 0.0088 0.0087
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0108 0.056 0.112
Echinococcus multilocularis isocitrate dehydrogenase 0.0013 0.0029 0.0028
Schistosoma mansoni biogenic amine (5HT) receptor 0.007 0.0346 0.0512
Leishmania major acetoin dehydrogenase e3 component-like protein 0.001 0.0015 0.0043
Echinococcus multilocularis neuropeptide FF receptor 2 0.007 0.0346 0.0345
Brugia malayi RE15519p 0.007 0.0346 0.205
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0012 0.0027 0.0038
Loa Loa (eye worm) hypothetical protein 0.0023 0.0087 0.0172
Loa Loa (eye worm) hypothetical protein 0.0009 0.0011 0.002
Brugia malayi Cytochrome P450 family protein 0.003 0.0124 0.0733
Trypanosoma cruzi GUP1, putative 0.0089 0.0451 1
Onchocerca volvulus 0.0036 0.0157 0.1623
Echinococcus granulosus serine:threonine protein kinase 0.0253 0.1364 0.2728
Plasmodium vivax thioredoxin reductase, putative 0.0029 0.0119 0.2004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0023 0.0087 0.0172
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.001 0.0014 0.0285
Brugia malayi Patched family protein 0.0009 0.0011 0.0065
Echinococcus multilocularis ecdysone induced protein 78C 0.0023 0.0087 0.0086
Echinococcus multilocularis sodium and chloride dependent glycine 0.002 0.0071 0.0071
Schistosoma mansoni hypothetical protein 0.0051 0.0243 0.036
Loa Loa (eye worm) hypothetical protein 0.0011 0.002 0.0037
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.007 0.0346 0.0691
Loa Loa (eye worm) hypothetical protein 0.0009 0.0011 0.002
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0037 0.0164 1
Schistosoma mansoni opsin-like receptor 0.007 0.0346 0.0512
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.007 0.0346 0.0345
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.001 0.0014 0.0026
Trypanosoma brucei trypanothione reductase 0.0029 0.0119 0.2616
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0089 0.0451 0.0902
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0035 0.0154 0.1394
Brugia malayi ecdysone receptor 0.0011 0.002 0.0116
Schistosoma mansoni sex comb on midleg homolog 0.0038 0.017 0.0251
Echinococcus granulosus sex peptide receptor 0.007 0.0346 0.0691
Schistosoma mansoni sterol O-acyltransferase 1 0.0909 0.4997 0.7407
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Loa Loa (eye worm) hypothetical protein 0.0011 0.002 0.0037
Schistosoma mansoni lamin 0.0022 0.0079 0.0115
Loa Loa (eye worm) hypothetical protein 0.0009 0.0011 0.002
Loa Loa (eye worm) aspartyl protease 6 0.0034 0.0149 0.0297
Schistosoma mansoni hypothetical protein 0.0051 0.0243 0.036
Brugia malayi hypothetical protein 0.002 0.0073 0.043
Plasmodium falciparum cGMP-specific phosphodiesterase 0.001 0.0014 0.0218
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0089 0.0451 0.0668
Plasmodium falciparum glutathione reductase 0.0029 0.0119 0.2004
Brugia malayi neuropeptide F receptor 0.007 0.0346 0.205
Loa Loa (eye worm) hypothetical protein 0.0009 0.0011 0.002
Plasmodium falciparum ataxin-2 like protein, putative 0.0036 0.0161 0.2718
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.001 0.0014 0.0117
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.007 0.0346 0.0512
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.001 0.0017 0.0016
Trichomonas vaginalis glutathione reductase, putative 0.001 0.0015 0.0126
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.002 0.0071 0.0105
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0013 0.0108
Onchocerca volvulus 0.0011 0.002 0.0195
Echinococcus granulosus SAM and MBT domain containing protein 0.0038 0.017 0.0339
Loa Loa (eye worm) hypothetical protein 0.0011 0.002 0.0037
Onchocerca volvulus 0.007 0.0346 0.3595
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0035 0.0154 0.1394
Loa Loa (eye worm) hypothetical protein 0.002 0.0071 0.0141
Loa Loa (eye worm) hypothetical protein 0.0011 0.002 0.0037
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Trypanosoma cruzi major cysteine proteinase, putative 0.0029 0.0119 0.2624
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0011 0.0019 0.0109
Loa Loa (eye worm) cytochrome P450 family protein 0.0012 0.0025 0.0048
Brugia malayi sulfakinin receptor protein 0.007 0.0346 0.205
Loa Loa (eye worm) hypothetical protein 0.0037 0.0164 0.0326
Trypanosoma cruzi cytochrome P450, putative 0.0012 0.0025 0.053
Schistosoma mansoni acetyl-CoA synthetase 0.0011 0.0019 0.0028
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0038 0.017 0.0251
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.001 0.0014 0.0026
Brugia malayi hypothetical protein 0.0007 0.0001 0.0005
Echinococcus multilocularis protein patched 0.0066 0.0324 0.0323
Leishmania major glycerol uptake protein, putative 0.0089 0.0451 1
Loa Loa (eye worm) steroid hormone receptor 0.0023 0.0087 0.0172
Plasmodium falciparum plasmepsin VI 0.0108 0.056 0.9508
Toxoplasma gondii hypothetical protein 0.0025 0.01 0.0212
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0035 0.0154 0.1394
Brugia malayi Myosin head containing protein 0.0009 0.0011 0.0065
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0089 0.0451 0.0451
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0206 0.1101 0.2201
Trichomonas vaginalis D-aminoacylase, putative 0.0023 0.0088 0.0791
Leishmania major trypanothione reductase 0.0029 0.0119 0.2415
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.0087 0.0172
Brugia malayi orphan nuclear receptor NR2E1 0.0011 0.002 0.0116
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.007 0.0346 0.0691
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0149 0.022
Entamoeba histolytica acyl-CoA synthetase, putative 0.0037 0.0164 0.2019
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0023 0.0087 0.0086
Echinococcus granulosus fmrfamide receptor 0.007 0.0346 0.0691
Loa Loa (eye worm) hypothetical protein 0.0066 0.0324 0.0646
Schistosoma mansoni amine GPCR 0.007 0.0346 0.0512
Schistosoma mansoni sodium-dependent amino acid transporter 0.002 0.0071 0.0105
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0035 0.0154 0.1394
Loa Loa (eye worm) fibroinase 0.001 0.0013 0.0024
Plasmodium vivax hypothetical protein, conserved 0.002 0.0071 0.1199
Schistosoma mansoni nuclear hormone receptor 0.0011 0.002 0.0028
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.001 0.0014 0.0218
Schistosoma mansoni serine/threonine protein kinase 0.0008 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0009 0.0011 0.002
Echinococcus granulosus somatostatin receptor 0.007 0.0346 0.0691
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0037 0.0163 0.3588
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.001 0.0014 0.0019
Brugia malayi ecdysteroid receptor 0.0023 0.0087 0.0514
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Onchocerca volvulus 0.0023 0.0088 0.0906
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0013 0.0108
Loa Loa (eye worm) hypothetical protein 0.0011 0.002 0.0037
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0014 0.0285
Loa Loa (eye worm) hypothetical protein 0.0909 0.4997 1
Plasmodium vivax aspartyl protease, putative 0.0034 0.0149 0.252
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.007 0.0346 0.0691
Brugia malayi hypothetical protein 0.0023 0.0089 0.0529
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0023 0.0087 0.0514
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.001 0.0014 0.0027
Schistosoma mansoni nuclear receptor nhr-48 0.0011 0.002 0.0028
Plasmodium falciparum plasmepsin VII 0.0034 0.0149 0.252
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.001 0.0014 0.0019
Loa Loa (eye worm) hypothetical protein 0.0009 0.0011 0.002
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.001 0.0014 0.0027
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.001 0.0014 0.0013
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0011 0.0019 0.0414
Onchocerca volvulus 0.0011 0.002 0.0195
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.001 0.0015 0.0307
Echinococcus multilocularis X box binding protein 1 0.023 0.1233 0.1232
Onchocerca volvulus 0.0036 0.0157 0.1623
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0011 0.0019 0.0414
Brugia malayi hypothetical protein 0.0011 0.002 0.0116
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.001 0.0013 0.0108
Echinococcus granulosus Niemann Pick C1 protein 0.0153 0.0808 0.1616
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Schistosoma mansoni hypothetical protein 0.007 0.0346 0.0512
Echinococcus granulosus o acyltransferase membrane bound domain 0.0089 0.0451 0.0902
Onchocerca volvulus 0.007 0.0346 0.3595
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.001 0.0013 0.0108
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0011 0.0019 0.1144
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0011 0.0019 0.004
Echinococcus multilocularis sodium and chloride dependent glycine 0.002 0.0071 0.0071
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0089 0.0451 0.0668
Brugia malayi Cathepsin L-like precursor 0.001 0.0013 0.0076
Schistosoma mansoni opsin-like receptor 0.007 0.0346 0.0512
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0011 0.0019 0.0109
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.001 0.0015 0.0235
Trichomonas vaginalis replication factor C large subunit, putative 0.0007 0.0001 0.0000031297
Schistosoma mansoni memapsin-2 (A01 family) 0.0034 0.0149 0.022
Brugia malayi beta-lactamase family protein 0.0023 0.0088 0.052
Brugia malayi Latrophilin receptor protein 2 0.0051 0.0243 0.1441
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0089 0.0451 0.0451
Echinococcus granulosus GPCR family 2 0.0051 0.0243 0.0485
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.007 0.0346 0.0345
Echinococcus granulosus Protein kinase C brain isozyme 0.0008 0.0004 0.0006
Echinococcus multilocularis neuropeptides capa receptor 0.007 0.0346 0.0345
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0164 1
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0088 0.1931
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.001 0.0014 0.0019
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0095 0.0484 0.0967
Brugia malayi beta-lactamase 0.0023 0.0088 0.052
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0023 0.0087 0.0172
Brugia malayi hypothetical protein 0.0012 0.0027 0.0158
Loa Loa (eye worm) hypothetical protein 0.0015 0.0044 0.0086
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.001 0.0014 0.0081
Loa Loa (eye worm) hypothetical protein 0.0144 0.0756 0.1511
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0089 0.0451 0.0451
Loa Loa (eye worm) serotonin transporter b 0.0119 0.0619 0.1237
Trypanosoma cruzi trypanothione reductase, putative 0.0029 0.0119 0.2616
Schistosoma mansoni serine/threonine protein kinase 0.0008 0.0004 0.0005
Brugia malayi Patched family protein 0.0009 0.0011 0.0065
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.0087 0.0086
Echinococcus granulosus neuropeptide FF receptor 2 0.007 0.0346 0.0691
Plasmodium vivax aspartyl proteinase, putative 0.0034 0.0149 0.252
Echinococcus granulosus neuropeptide Y receptor 0.007 0.0346 0.0691
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0035 0.0154 0.1394
Loa Loa (eye worm) hypothetical protein 0.002 0.0071 0.0141
Schistosoma mansoni retinoic acid receptor RXR 0.0023 0.0087 0.0127
Loa Loa (eye worm) hypothetical protein 0.0119 0.0619 0.1237
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.002 0.0071 0.0105
Echinococcus multilocularis orexin receptor type 2 0.007 0.0346 0.0345
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0014 0.0285
Loa Loa (eye worm) hypothetical protein 0.0011 0.002 0.0037
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.001 0.0014 0.0117
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0451 0.4097
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0023 0.0087 0.0514
Echinococcus granulosus orexin receptor type 2 0.007 0.0346 0.0691
Onchocerca volvulus 0.0011 0.0019 0.0194
Onchocerca volvulus 0.0022 0.0079 0.081
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.001 0.0015 0.0307
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.001 0.0014 0.0027
Loa Loa (eye worm) hypothetical protein 0.0009 0.0011 0.002
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.001 0.0015 0.0235
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0029 0.0123 0.0726
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.007 0.0346 0.205
Echinococcus multilocularis cysteine protease 0.001 0.0013 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0013 0.0108
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.007 0.0346 0.0345
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.001 0.0015 0.003
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0023 0.0087 0.0086
Onchocerca volvulus 0.0029 0.0122 0.126
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0029 0.0118 0.0235
Brugia malayi hypothetical protein 0.0036 0.0161 0.0952
Echinococcus multilocularis sterol O acyltransferase 1 0.0909 0.4997 0.4996
Trypanosoma cruzi cruzipain precursor, putative 0.0037 0.0163 0.3588
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0011 0.002 0.0195
Schistosoma mansoni hypothetical protein 0.007 0.0346 0.0512
Loa Loa (eye worm) hypothetical protein 0.0034 0.0149 0.0297
Trichomonas vaginalis glucosylceramidase, putative 0.0206 0.1101 1
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0089 0.0451 0.0451
Loa Loa (eye worm) MH2 domain-containing protein 0.0095 0.0487 0.0973
Echinococcus multilocularis myosin light chain kinase, smooth muscle 0.0253 0.1364 0.1363
Onchocerca volvulus 0.007 0.0346 0.3595
Entamoeba histolytica hypothetical protein 0.0029 0.0118 0.1457
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0011 0.0019 0.0317
Brugia malayi hypothetical protein 0.007 0.0346 0.205
Echinococcus multilocularis nuclear receptor nhr 48 0.0011 0.002 0.0019
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0089 0.0451 0.766
Echinococcus multilocularis cysteine protease 0.001 0.0013 0.0012
Loa Loa (eye worm) nuclear hormone receptor 0.0083 0.0417 0.0832
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Brugia malayi nuclear receptor RXR 0.0011 0.002 0.0116
Echinococcus granulosus histone acetyltransferase MYST2 0.0043 0.0199 0.0398
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.001 0.0014 0.0218
Brugia malayi nuclear hormone receptor family member nhr-6 0.0011 0.002 0.0116
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0012 0.0027 0.0052
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.001 0.0014 0.0285
Echinococcus multilocularis tachykinin peptides receptor 99D 0.007 0.0346 0.0345
Echinococcus granulosus cathepsin L cysteine proteinase 0.001 0.0013 0.0024
Echinococcus granulosus thioredoxin glutathione reductase 0.0029 0.0119 0.0236
Echinococcus multilocularis replication factor c subunit 1 0.0007 0.0001 0.00000034425
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.001 0.0014 0.0117
Plasmodium falciparum cysteine proteinase falcipain 2b 0.001 0.0013 0.0203
Echinococcus granulosus uncharacterized sodium dependent transporter 0.002 0.0071 0.0141
Echinococcus granulosus neuropeptide receptor 0.007 0.0346 0.0691
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0148 0.078 1
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0022 0.0079 0.0156
Brugia malayi G-protein coupled receptor 0.007 0.0346 0.205
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.002 0.0071 0.0141
Leishmania major glycerol uptake protein, putative 0.0089 0.0451 1
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0206 0.1101 0.6518
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.007 0.0346 0.0691
Brugia malayi tailless protein 0.0011 0.002 0.0116
Onchocerca volvulus 0.002 0.0071 0.0734
Schistosoma mansoni sodium/chloride dependent transporter 0.002 0.0071 0.0105
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0149 0.022
Brugia malayi hypothetical protein 0.002 0.0073 0.043
Echinococcus multilocularis lamin dm0 0.0022 0.0079 0.0078
Brugia malayi ORL1-like opioid receptor 0.007 0.0346 0.205
Plasmodium vivax vivapain-2 0.001 0.0013 0.0203
Trypanosoma cruzi glycerol uptake protein, putative 0.0089 0.0451 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0088 0.0174
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0052
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0011 0.002 0.0019
Echinococcus multilocularis allatostatin A receptor 0.007 0.0346 0.0345
Brugia malayi Sodium:neurotransmitter symporter family protein 0.002 0.0071 0.0422
Echinococcus multilocularis thioredoxin glutathione reductase 0.0029 0.0119 0.0118
Toxoplasma gondii hypothetical protein 0.0089 0.0451 0.0963
Mycobacterium ulcerans putative regulatory protein 0.0025 0.01 0.6081
Brugia malayi Patched protein homolog 1 0.0009 0.0011 0.0065
Brugia malayi DKFZp564C0469 protein 0.0007 0.0001 0.0005
Onchocerca volvulus 0.002 0.0073 0.0747
Loa Loa (eye worm) hypothetical protein 0.0277 0.1494 0.2989
Brugia malayi beta-lactamase family protein 0.0023 0.0088 0.052
Brugia malayi G protein-coupled receptor 0.007 0.0346 0.205
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.001 0.0014 0.0117
Trichomonas vaginalis glucosylceramidase, putative 0.0135 0.0708 0.6432
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0013 0.0108
Plasmodium vivax hypothetical protein, conserved 0.0025 0.01 0.1685
Trypanosoma cruzi cysteine peptidase, putative 0.0037 0.0163 0.3588
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0034 0.0149 0.022
Brugia malayi follicle stimulating hormone receptor 0.007 0.0346 0.205
Brugia malayi latrophilin 2 splice variant baaae 0.0111 0.0573 0.3392
Brugia malayi isocitrate dehydrogenase 0.0013 0.0029 0.0173
Echinococcus granulosus endonuclease exonuclease phosphatase 0.015 0.079 0.158
Echinococcus granulosus rhodopsin orphan GPCR 0.007 0.0346 0.0691
Loa Loa (eye worm) hypothetical protein 0.0036 0.0157 0.0312
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.001 0.0015 0.0307
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0066 0.0323 0.8882
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.002 0.0071 0.0141
Brugia malayi Cathepsin L-like precursor 0.001 0.0013 0.0076
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0023 0.0088 0.0998
Mycobacterium ulcerans acyl-CoA synthetase 0.0011 0.0019 0.1144
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0035 0.0154 0.1394
Onchocerca volvulus 0.001 0.0013 0.0124
Echinococcus granulosus expressed conserved protein 0.0144 0.0757 0.1513
Loa Loa (eye worm) patched family protein 0.0009 0.0011 0.002
Schistosoma mansoni hypothetical protein 0.0089 0.0451 0.0668
Onchocerca volvulus 0.0038 0.017 0.1763
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0037 0.0163 0.3588
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0025 0.01 0.1156
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.007 0.0346 0.0691
Brugia malayi hypothetical protein 0.0009 0.0011 0.0065
Loa Loa (eye worm) hypothetical protein 0.001 0.0015 0.0028
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.002 0.0019
Plasmodium falciparum plasmepsin IV 0.0108 0.056 0.9508
Echinococcus granulosus intermediate filament protein 0.0022 0.0079 0.0156
Onchocerca volvulus Protein ultraspiracle homolog 0.0023 0.0087 0.0895
Onchocerca volvulus Bile acid receptor homolog 0.0023 0.0087 0.0895
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0043 0.0199 0.1181
Echinococcus multilocularis microtubule associated protein 2 0.0396 0.2156 0.2155
Schistosoma mansoni growth hormone secretagogue receptor 0.007 0.0346 0.0512
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0037 0.0163 0.3588
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Schistosoma mansoni zinc finger protein 0.0011 0.002 0.0028
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0023 0.0087 0.0127
Loa Loa (eye worm) mbt repeat family protein 0.0038 0.017 0.0339
Mycobacterium tuberculosis Probable hydrolase 0.0023 0.0088 0.0998
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.001 0.0014 0.0013
Loa Loa (eye worm) hypothetical protein 0.0302 0.1635 0.327
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0023 0.0087 0.0514
Trypanosoma cruzi GUP1, putative 0.0089 0.0451 1
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0013 0.0108
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0007 0.0001 0.0000031297
Echinococcus multilocularis neuropeptide Y receptor 0.007 0.0346 0.0345
Schistosoma mansoni neuropeptide receptor 0.007 0.0346 0.0512
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0051 0.0243 0.0243
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0011 0.002 0.0019
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0108 0.056 0.1195
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0011 0.0019 0.1144
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0013 0.0108
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0156 0.0821 0.1216
Loa Loa (eye worm) hypothetical protein 0.001 0.0014 0.0026
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.0087 0.0172
Brugia malayi Patched related family protein 12 0.0009 0.0011 0.0065
Onchocerca volvulus 0.0119 0.0619 0.643
Schistosoma mansoni cathepsin D (A01 family) 0.039 0.2123 0.3146
Brugia malayi hypothetical protein 0.007 0.0346 0.205
Brugia malayi Tachykinin-like peptides receptor 99D 0.007 0.0346 0.205
Brugia malayi AMP-binding enzyme family protein 0.0011 0.0019 0.0115
Leishmania major hypothetical protein, conserved 0.001 0.0014 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0023 0.0087 0.0514
Brugia malayi hypothetical protein 0.0029 0.0118 0.0701
Echinococcus multilocularis rhodopsin orphan GPCR 0.007 0.0346 0.0345
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0029 0.0118 0.0118
Loa Loa (eye worm) nuclear receptor NHR-67 0.0011 0.002 0.0037
Onchocerca volvulus 0.007 0.0346 0.3595
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.0104 0.1206
Schistosoma mansoni intermediate filament proteins 0.0022 0.0079 0.0115
Plasmodium vivax vivapain-2 0.001 0.0013 0.0203
Mycobacterium ulcerans beta-lactamase 0.0023 0.0088 0.5337
Trichomonas vaginalis glucosylceramidase, putative 0.0135 0.0708 0.6432
Loa Loa (eye worm) patched family protein 0.0009 0.0011 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0324 0.2935
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0013 0.0108
Onchocerca volvulus 0.0011 0.0019 0.0194
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0089 0.0451 0.0668
Loa Loa (eye worm) hypothetical protein 0.0081 0.0406 0.081
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0011 0.0019 0.0109
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0011 0.002 0.0019
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0037 0.0163 0.3588
Trypanosoma cruzi cysteine peptidase, putative 0.0037 0.0163 0.3588
Echinococcus multilocularis rhodopsin orphan GPCR 0.007 0.0346 0.0345
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.002 0.0071 0.0105
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.001 0.0014 0.0013
Loa Loa (eye worm) hypothetical protein 0.002 0.0071 0.0141
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0011 0.0019 0.0037
Toxoplasma gondii ATPase, AAA family protein 0.0007 0.0001 0.00000073543
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0066 0.0324 0.0646
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0007 0.0001 0.0005
Plasmodium falciparum glutathione reductase 0.001 0.0015 0.0235
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.001 0.0015 1
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0014 0.0285
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0035 0.0154 0.0227
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0035 0.0154 0.1394
Brugia malayi Cathepsin L-like precursor 0.001 0.0013 0.0076
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0035 0.0154 0.1394
Toxoplasma gondii patched family protein 0.0009 0.0011 0.0022
Trichomonas vaginalis penicillin-binding protein, putative 0.0023 0.0088 0.0791
Onchocerca volvulus 0.007 0.0346 0.3595
Plasmodium falciparum cysteine proteinase falcipain 2a 0.001 0.0013 0.0203
Loa Loa (eye worm) hypothetical protein 0.0023 0.0088 0.0174
Echinococcus granulosus sodium and chloride dependent glycine 0.002 0.0071 0.0141
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.001 0.0015 0.0043
Trypanosoma cruzi glycerol uptake protein, putative 0.0089 0.0451 1
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0088 0.1931
Brugia malayi LBP / BPI / CETP family, N-terminal domain containing protein 0.0036 0.0157 0.0928
Schistosoma mansoni rhodopsin-like orphan GPCR 0.007 0.0346 0.0512
Brugia malayi Nuclear hormone receptor E75 0.0011 0.002 0.0116
Schistosoma mansoni biogenic amine (dopamine) receptor 0.007 0.0346 0.0512
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0014 0.0117
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.001 0.0014 0.0285
Entamoeba histolytica hypothetical protein 0.0089 0.0451 0.5582
Schistosoma mansoni nuclear hormone receptor 0.0023 0.0087 0.0127
Echinococcus multilocularis protein kinase c epsilon type 0.0008 0.0004 0.0003
Treponema pallidum NADH oxidase 0.001 0.0015 0.0224
Brugia malayi AMP-binding enzyme family protein 0.0011 0.0019 0.0115
Mycobacterium tuberculosis Probable reductase 0.0066 0.0323 0.4055
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0035 0.0154 0.0227
Onchocerca volvulus Cathepsin L homolog 0.001 0.0013 0.0124
Loa Loa (eye worm) hypothetical protein 0.0023 0.0087 0.0172
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.001 0.0013 0.0108
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0028 0.0112 1
Trichomonas vaginalis transmembrane protein nessy, putative 0.0089 0.0451 0.4097
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0013 0.0029 0.0028
Echinococcus multilocularis Niemann Pick C1 protein 0.0153 0.0808 0.0807
Schistosoma mansoni survival motor neuron protein 0.0029 0.0122 0.018
Onchocerca volvulus 0.0036 0.0157 0.1623
Echinococcus multilocularis histone acetyltransferase MYST2 0.0043 0.0199 0.0199
Loa Loa (eye worm) hypothetical protein 0.0023 0.0087 0.0172
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.002 0.0071 0.0151
Schistosoma mansoni hypothetical protein 0.0135 0.0708 0.1049
Schistosoma mansoni patched 1 0.0066 0.0324 0.0479
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.001 0.0015 0.0046
Brugia malayi AMP-binding enzyme family protein 0.0011 0.0019 0.0115
Brugia malayi MH2 domain containing protein 0.0095 0.0487 0.2884
Loa Loa (eye worm) hypothetical protein 0.0181 0.0962 0.1923
Brugia malayi Sodium:neurotransmitter symporter family protein 0.002 0.0071 0.0422
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0043 0.0199 0.0199
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0037 0.0163 0.3588
Onchocerca volvulus 0.0009 0.0011 0.0105
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0011 0.0019 0.1144
Loa Loa (eye worm) hypothetical protein 0.007 0.0346 0.0691
Schistosoma mansoni neuropeptide F-like receptor 0.007 0.0346 0.0512
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0119 0.0619 0.3663
Echinococcus multilocularis cathepsin l cysteine peptidase 0.001 0.0013 0.0012
Trypanosoma brucei glycerol uptake protein, putative 0.0089 0.0451 1
Brugia malayi LBP / BPI / CETP family, C-terminal domain containing protein 0.0036 0.0157 0.0928
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.007 0.0346 0.0691
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.007 0.0346 0.0345
Schistosoma mansoni chromosome transmission fidelity factor 0.0007 0.0001 0.00000051034
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.001 0.0014 0.0019
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0052
Schistosoma mansoni hypothetical protein 0.0029 0.0118 0.0174
Brugia malayi hypothetical protein 0.0015 0.0044 0.0258
Trichomonas vaginalis glucosylceramidase, putative 0.0135 0.0708 0.6432
Echinococcus multilocularis cathepsin L cysteine protease 0.001 0.0013 0.0012
Loa Loa (eye worm) thioredoxin reductase 0.0029 0.0119 0.0236
Entamoeba histolytica cysteine proteinase, putative 0.001 0.0013 0.0148
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.001 0.0014 0.0081
Brugia malayi AMP-binding enzyme family protein 0.0037 0.0164 0.097
Brugia malayi hypothetical protein 0.0181 0.0962 0.5694
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0012 0.0026 0.0054
Leishmania major hypothetical protein, conserved 0.0023 0.0088 0.1711
Toxoplasma gondii cathepsin CPL 0.001 0.0013 0.0025

Activities

Activity type Activity value Assay description Source Reference
-Log IC50 (binding) = 3.94 Inhibition of dopamine beta hydroxylase ChEMBL. 7783140
-Log IC50 (binding) = 3.94 Inhibition of dopamine beta-hydroxylase (DbetaH) in hypertensive rats when administered orally (or) intraperitoneally ChEMBL. 2296023
Decrease (functional) ND 0 mM Mean arterial blood pressure at 4 h post drug at ip dose of 50 mg/kg for the indicated number of SHR (spontaneous hypertensive rats) relative to blood pressure before dosing;ND is defined as no-data ChEMBL. 3820219
Decrease (functional) ND 0 mM Mean arterial blood pressure at 4 h post drug at po dose of 50 mg/kg for the indicated number of SHR (spontaneous hypertensive rats) relative to blood pressure before dosing (expt. no. 12);ND is defined as no-data ChEMBL. 3820219
IC50 (binding) = 3.94 Inhibition of dopamine beta hydroxylase ChEMBL. 7783140
IC50 (binding) = 3.94 Inhibition of dopamine beta-hydroxylase (DbetaH) in hypertensive rats when administered orally (or) intraperitoneally ChEMBL. 2296023
IC50 (binding) = 3.94 Inhibition of dopamine beta-hydroxylase (DbetaH) enzyme ChEMBL. 9435905
Increase (functional) ND 0 % Change in DA/NE (Dopamine/Norepinephrine) ratio after oral dosing (50 mg/kg); ND is defined as no-data. ChEMBL. 3820219
Inhibition (binding) = 43 % Percent inhibition against bovine Dopamine beta hydroxylase (DBH) at 10E-4 M ChEMBL. 3820219
Inhibition (binding) = 43 % Percent inhibition against bovine Dopamine beta hydroxylase (DBH) at 10E-4 M ChEMBL. 3820219
Kis (binding) ND 0 uM Inhibitor dissociation constant vs. tyramine substrate against Dopamine beta hydroxylase at pH 4.5;ND is defined as no-data. ChEMBL. 3820219
Kis (binding) ND 0 uM Inhibitor dissociation constant vs. tyramine substrate against Dopamine beta hydroxylase at pH 6.6;ND is defined as no-data ChEMBL. 3820219
Kis (binding) = 3.42 uM Inhibitor dissociation constant vs. tyramine substrate against Dopamine beta hydroxylase at pH 6.0 ChEMBL. 3820219
Kis (binding) = 3.42 uM Inhibitor dissociation constant vs. tyramine substrate against Dopamine beta hydroxylase at pH 6.0 ChEMBL. 3820219
logP (ADMET) ND 0 Partition coefficient (logP) ChEMBL. 3820219

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

4 literature references were collected for this gene.

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