Detailed information for compound 1362913

Basic information

Technical information
  • TDR Targets ID: 1362913
  • Name: 5-[(4-fluorophenyl)amino]-3-methyl-1,3-thiazo lidine-2,4-dione
  • MW: 240.254 | Formula: C10H9FN2O2S
  • H donors: 1 H acceptors: 2 LogP: 2.17 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN1C(=O)SC(C1=O)Nc1ccc(cc1)F
  • InChi: 1S/C10H9FN2O2S/c1-13-9(14)8(16-10(13)15)12-7-4-2-6(11)3-5-7/h2-5,8,12H,1H3
  • InChiKey: RBQYQECJIWYHGM-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 5-[(4-fluorophenyl)amino]-3-methyl-thiazolidine-2,4-dione
  • 5-[(4-fluorophenyl)amino]-3-methylthiazolidine-2,4-dione
  • 5-[(4-fluorophenyl)amino]-3-methyl-thiazolidine-2,4-quinone
  • BAS 07297790
  • 5-(4-Fluoro-phenylamino)-3-methyl-thiazolidine-2,4-dione
  • MLS000034993
  • STK201140
  • SMR000014328

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Influenza A virus Nonstructural protein 1 Starlite/ChEMBL No references
Homo sapiens neuropeptide S receptor 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum IPR000276,Rhodopsin-like GPCR superfamily,domain-containing Get druggable targets OG5_136011 All targets in OG5_136011
Echinococcus granulosus neuropeptide receptor A26 Get druggable targets OG5_136011 All targets in OG5_136011
Echinococcus multilocularis neuropeptide s receptor Get druggable targets OG5_136011 All targets in OG5_136011
Echinococcus granulosus neuropeptide s receptor Get druggable targets OG5_136011 All targets in OG5_136011
Echinococcus multilocularis neuropeptide receptor A26 Get druggable targets OG5_136011 All targets in OG5_136011
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Mycobacterium tuberculosis Hypothetical protein Nonstructural protein 1   230 aa 202 aa 23.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis CMGC family protein kinase 0.067 0.087 0.946
Brugia malayi Protein kinase domain containing protein 0.0175 0.0095 0.0084
Trichomonas vaginalis CMGC family protein kinase 0.0172 0.0091 0.0986
Trypanosoma brucei Serine/threonine-protein kinase NEK11, putative 0.0117 0.0004 0.0041
Schistosoma mansoni protein kinase 0.0633 0.0811 0.2529
Onchocerca volvulus 0.0175 0.0095 0.0133
Trypanosoma brucei casein kinase I, isoform 2 0.0294 0.0282 0.3065
Echinococcus multilocularis epidermal growth factor receptor 0.0786 0.1051 0.1978
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0294 0.0282 0.3065
Trichomonas vaginalis STE family protein kinase 0.0117 0.0004 0.0041
Brugia malayi Protein kinase domain containing protein 0.1875 0.2755 0.2747
Loa Loa (eye worm) thyroid receptor interactor 0.0351 0.037 0.036
Trichomonas vaginalis CAMK family protein kinase 0.0364 0.039 0.4243
Loa Loa (eye worm) IKK protein kinase 0.1033 0.1438 0.1429
Plasmodium falciparum serine/threonine protein kinase 0.0153 0.0061 0.066
Echinococcus granulosus cyclin dependent kinase 7 0.0487 0.0584 0.1756
Trichomonas vaginalis CAMK family protein kinase 0.0635 0.0814 0.8855
Trypanosoma cruzi cdc2-related kinase 1 0.0702 0.0919 1
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0036 0.0391
Trichomonas vaginalis AGC family protein kinase 0.012 0.0008 0.0092
Schistosoma mansoni serine/threonine protein kinase 0.0834 0.1126 0.3515
Echinococcus granulosus cyclin dependent kinase 0.0702 0.0919 0.2815
Echinococcus granulosus epidermal growth factor receptor 0.0786 0.1051 0.323
Loa Loa (eye worm) CDC7 protein kinase 0.0665 0.0862 0.0852
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0036 0.0391
Toxoplasma gondii casein kinase I 0.0294 0.0282 0.3065
Schistosoma mansoni serine/threonine protein kinase 0.0211 0.0151 0.0462
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0702 0.0919 1
Schistosoma mansoni protein kinase 0.0137 0.0035 0.0099
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.025 0.0213 0.2317
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0469 0.0555 0.1665
Echinococcus multilocularis activin receptor type 0.0559 0.0695 0.1291
Trichomonas vaginalis CMGC family protein kinase 0.0137 0.0035 0.0384
Schistosoma mansoni serine/threonine protein kinase 0.0757 0.1006 0.3139
Echinococcus granulosus serine/threonine protein kinase 0.0253 0.0218 0.06
Toxoplasma gondii AGC kinase 0.0441 0.0512 0.5568
Echinococcus granulosus cGMP dependent protein kinase 1 0.0211 0.0151 0.0391
Trichomonas vaginalis serine/threonine-protein kinase, putative 0.012 0.0008 0.0092
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0256 0.0222 0.2413
Trichomonas vaginalis AGC family protein kinase 0.012 0.0008 0.0092
Loa Loa (eye worm) hypothetical protein 0.023 0.0182 0.0171
Loa Loa (eye worm) hypothetical protein 0.0297 0.0285 0.0275
Schistosoma mansoni tyrosine kinase 0.0676 0.0879 0.2741
Brugia malayi Protein kinase domain containing protein 0.0635 0.0814 0.0804
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0161 0.0074 0.0146
Loa Loa (eye worm) SRC-1 0.0356 0.0378 0.0367
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0661 0.0856 0.9307
Schistosoma mansoni tyrosine kinase 0.0461 0.0542 0.1688
Leishmania major serine/threonine-protein kinase, putative 0.0117 0.0004 0.0041
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0247 0.0207 0.0197
Brugia malayi serine/threonine-protein kinase 6 0.028 0.026 0.0249
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.025 0.0213 0.2317
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0151 0.0057 0.062
Echinococcus granulosus CDC7 cell division cycle 7 0.0665 0.0862 0.2632
Trypanosoma brucei cdc2-related kinase 1 0.0702 0.0919 1
Trichomonas vaginalis STE family protein kinase 0.0203 0.0139 0.151
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.028 0.026 0.0988
Schistosoma mansoni serine/threonine protein kinase 0.028 0.026 0.0802
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0414 0.0469 0.1394
Echinococcus granulosus raf serine:threonine protein kinase 0.0168 0.0084 0.0179
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0344 0.0359 0.1046
Trichomonas vaginalis CAMK family protein kinase 0.0142 0.0044 0.0477
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0344 0.0359 0.0641
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0702 0.0919 0.091
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0151 0.0058 0.0059
Entamoeba histolytica protein kinase, putative 0.0153 0.0061 0.0231
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0553 0.0686 0.7465
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.1794 0.2628 0.5026
Trypanosoma cruzi casein kinase, putative 0.0294 0.0282 0.3065
Echinococcus granulosus c-Jun N-terminal kinases 0.0591 0.0746 0.2267
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0662 0.0857 0.2618
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0256 0.0222 0.0376
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0036 0.0391
Trichomonas vaginalis CMGC family protein kinase 0.0154 0.0062 0.0673
Plasmodium falciparum calcium-dependent protein kinase 5 0.0256 0.0222 0.2413
Loa Loa (eye worm) hypothetical protein 0.0204 0.014 0.0129
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0159 0.0069 0.0059
Brugia malayi Temporarily assigned gene name protein 59 0.0145 0.0048 0.0038
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0501 0.0605 0.1117
Giardia lamblia Kinase, CAMK CAMKL 0.0137 0.0035 0.0345
Schistosoma mansoni tyrosine kinase 0.0676 0.0879 0.2741
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0294 0.0282 0.0271
Toxoplasma gondii aurora kinase 0.028 0.026 0.2823
Brugia malayi Furin-like cysteine rich region family protein 0.0786 0.1051 0.1041
Brugia malayi Protein kinase domain containing protein 0.0129 0.0023 0.0013
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0302 0.0294 0.0842
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0151 0.0057 0.062
Echinococcus granulosus Protein kinase C brain isozyme 0.0426 0.0487 0.1451
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0156 0.0066 0.0055
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0121 0.0011 0.0116
Schistosoma mansoni protein kinase 0.0172 0.0091 0.0272
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0156 0.0065 0.0117
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0139 0.0039 0.0037
Echinococcus granulosus serine:threonine protein kinase 0.0142 0.0044 0.0052
Leishmania major protein kinase A catalytic subunit isoform 2 0.0661 0.0856 0.9307
Echinococcus granulosus cyclin dependent kinase 19 0.0487 0.0583 0.1752
Trypanosoma cruzi polo-like protein kinase, putative 0.0364 0.039 0.4243
Trichomonas vaginalis AGC family protein kinase 0.0661 0.0856 0.9307
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Echinococcus granulosus dual specificity 0.0216 0.0159 0.0415
Trichomonas vaginalis AGC family protein kinase 0.012 0.0008 0.0092
Schistosoma mansoni nephrin 0.0245 0.0204 0.0627
Echinococcus granulosus casein kinase I alpha 0.0294 0.0282 0.0802
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0137 0.0035 0.0384
Echinococcus multilocularis N chimaerin 0.0161 0.0074 0.0089
Plasmodium vivax tyrosine kinase-like protein, putative 0.0151 0.0057 0.062
Brugia malayi Protein kinase domain containing protein 0.0553 0.0686 0.0676
Schistosoma mansoni serine/threonine protein kinase 0.0137 0.0035 0.0099
Echinococcus multilocularis cyclin dependent kinase 9 0.0326 0.0331 0.0586
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0151 0.0058 0.0047
Brugia malayi Protein kinase domain containing protein 0.0459 0.054 0.0529
Schistosoma mansoni protein kinase 0.1073 0.15 0.4689
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0181 0.0104 0.0396
Leishmania major protein kinase A catalytic subunit isoform 1 0.0661 0.0856 0.9307
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0154 0.0062 0.0673
Plasmodium falciparum serine/threonine protein kinase KIN 0.0183 0.0108 0.117
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0387 0.0427 0.1327
Brugia malayi Fibronectin type III domain containing protein 0.0204 0.014 0.0129
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0616 0.0784 0.2389
Echinococcus granulosus mitogen activated protein kinase 3 0.0154 0.0062 0.0108
Trichomonas vaginalis CMGC family protein kinase 0.0702 0.0919 1
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0591 0.0746 0.1388
Brugia malayi Protein kinase domain containing protein 0.0151 0.0058 0.0047
Schistosoma mansoni serine/threonine protein kinase 0.0139 0.0039 0.0111
Loa Loa (eye worm) hypothetical protein 0.0156 0.0065 0.0054
Giardia lamblia Kinase, CMGC DYRK 0.0216 0.0159 0.1696
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0502 0.0607 0.0597
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0635 0.0814 0.0804
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Leishmania major serine/threonine kinase-like protein, putative 0.0137 0.0035 0.0384
Schistosoma mansoni serine/threonine protein kinase 0.0702 0.0919 0.2869
Loa Loa (eye worm) AGC/PKA protein kinase 0.0661 0.0856 0.0846
Plasmodium vivax cyclin dependent kinase 7 (cdk7), putative 0.0137 0.0035 0.0384
Trichomonas vaginalis CMGC family protein kinase 0.0154 0.0062 0.0673
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0817 0.11 0.109
Echinococcus multilocularis transfer RNA-Thr 0.0259 0.0226 0.0384
Onchocerca volvulus 0.0175 0.0095 0.0133
Echinococcus granulosus tyrosine protein kinase Src42A 0.0356 0.0378 0.1105
Echinococcus granulosus serine:threonine protein kinase 0.0142 0.0044 0.0052
Brugia malayi Cam kinase protein 1 0.0256 0.0222 0.0211
Schistosoma mansoni serine/threonine protein kinase 0.0168 0.0084 0.0253
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0702 0.0919 1
Echinococcus multilocularis tyrosine protein kinase shark 0.081 0.1088 0.205
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0661 0.0856 0.1601
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0136 0.0034 0.0095
Trichomonas vaginalis AGC family protein kinase 0.0459 0.054 0.5867
Brugia malayi Protein kinase domain containing protein 0.0175 0.0095 0.0084
Trichomonas vaginalis AGC family protein kinase 0.0191 0.0121 0.1313
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0183 0.0108 0.117
Echinococcus multilocularis nervana 2 0.0139 0.0039 0.0022
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0661 0.0856 0.9307
Onchocerca volvulus Serine\/threonine kinase homolog 0.0244 0.0203 0.0478
Trichomonas vaginalis CAMK family protein kinase 0.0183 0.0108 0.117
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0183 0.0108 0.0097
Echinococcus multilocularis mitogen activated protein kinase 14 0.0366 0.0394 0.0709
Loa Loa (eye worm) hypothetical protein 0.0136 0.0034 0.0024
Echinococcus multilocularis Immunoglobulin 0.0193 0.0123 0.0185
Echinococcus granulosus tyrosine kinase 0.0175 0.0095 0.0213
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0274 0.025 0.024
Schistosoma mansoni tyrosine kinase 0.0726 0.0957 0.2986
Trypanosoma cruzi cdc2-related kinase 3 0.0702 0.0919 1
Schistosoma mansoni serine/threonine protein kinase 0.0298 0.0288 0.0889
Leishmania major mitogen-activated protein kinase, putative,map kinase-like protein 0.0137 0.0035 0.0384
Trichomonas vaginalis CMGC family protein kinase 0.0137 0.0035 0.0384
Brugia malayi P38 map kinase family protein 2 0.0366 0.0394 0.0384
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0303 0.0296 0.0519
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.067 0.087 0.946
Schistosoma mansoni tyrosine kinase 0.0356 0.0378 0.1171
Onchocerca volvulus 0.0387 0.0427 0.1191
Trichomonas vaginalis CAMK family protein kinase 0.0364 0.039 0.4243
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0216 0.0159 0.173
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Entamoeba histolytica protein kinase 2, putative 0.0236 0.019 0.0723
Trichomonas vaginalis CAMK family protein kinase 0.0183 0.0108 0.117
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0469 0.0555 0.0545
Echinococcus multilocularis mitogen activated protein kinase 11 0.0366 0.0394 0.0709
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0364 0.039 0.1144
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0244 0.0203 0.0554
Echinococcus granulosus dual specificity 0.0216 0.0159 0.0415
Giardia lamblia Kinase, AGC AKT 0.0263 0.0233 0.2507
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0366 0.0394 0.4288
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0121 0.0011 0.0116
Onchocerca volvulus 0.0198 0.0131 0.0247
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0169 0.0086 0.0113
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0285 0.0268 0.0257
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0216 0.0159 0.0149
Trichomonas vaginalis CMGC family protein kinase 0.0172 0.0091 0.0986
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0661 0.0856 0.1601
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0364 0.039 0.038
Trichomonas vaginalis CAMK family protein kinase 0.0183 0.0108 0.117
Trypanosoma cruzi cdc2-related kinase 3 0.0702 0.0919 1
Schistosoma mansoni hypothetical protein 0.0201 0.0136 0.0416
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0701 0.0919 0.9993
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0142 0.0044 0.0033
Toxoplasma gondii NEK kinase 0.0117 0.0004 0.0041
Echinococcus multilocularis 0.0213 0.0154 0.0245
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0154 0.0062 0.0673
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0154 0.0062 0.0673
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Echinococcus multilocularis nervana 2 0.0139 0.0039 0.0022
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0661 0.0856 0.9307
Echinococcus multilocularis mitogen activated protein kinase 3 0.0154 0.0062 0.0066
Echinococcus granulosus mitogen activated protein kinase 14 0.0366 0.0394 0.1158
Entamoeba histolytica protein kinase domain containing protein 0.0137 0.0035 0.0134
Trypanosoma brucei cdc2-related kinase 3 0.0702 0.0919 1
Schistosoma mansoni serine/threonine protein kinase 0.0211 0.0151 0.0462
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Loa Loa (eye worm) CAMK/PIM protein kinase 0.1875 0.2755 0.2747
Entamoeba histolytica protein kinase, putative 0.0441 0.0512 0.1948
Loa Loa (eye worm) TK/INSR protein kinase 0.0676 0.0879 0.0869
Brugia malayi Protein kinase domain containing protein 0.0877 0.1194 0.1185
Giardia lamblia Kinase, AGC PKA 0.0661 0.0856 0.9304
Schistosoma mansoni tyrosine kinase 0.0356 0.0378 0.1171
Brugia malayi Protein kinase domain containing protein 0.0734 0.097 0.0961
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0356 0.0378 0.1105
Echinococcus multilocularis cyclin dependent kinase 5 0.0702 0.0919 0.1724
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0366 0.0394 0.4288
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0661 0.0856 0.2614
Schistosoma mansoni ephrin receptor 0.0163 0.0076 0.0227
Echinococcus granulosus nervana 2 0.0139 0.0039 0.0036
Echinococcus granulosus casein kinase I alpha 0.0294 0.0282 0.0802
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0661 0.0856 0.2614
Echinococcus granulosus titin 0.0148 0.0053 0.008
Brugia malayi putative serine/threonine kinase SADA gamma 0.0183 0.0108 0.0097
Loa Loa (eye worm) protein kinase domain-containing protein 0.0299 0.029 0.0279
Entamoeba histolytica protein kinase, putative 0.0553 0.0686 0.2612
Plasmodium vivax casein kinase 1, putative 0.0294 0.0282 0.3065
Brugia malayi MAP kinase sur-1 0.0154 0.0062 0.0051
Brugia malayi casein kinase I 0.0294 0.0282 0.0271
Schistosoma mansoni tyrosine kinase 0.0156 0.0065 0.0191
Schistosoma mansoni serine/threonine protein kinase 0.0426 0.0487 0.1515
Trichomonas vaginalis CMGC family protein kinase 0.0702 0.0919 1
Entamoeba histolytica serine/threonine protein kinase, putative 0.0364 0.039 0.1484
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0253 0.0218 0.2367
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0183 0.0108 0.117
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0817 0.11 0.109
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0214 0.0156 0.0404
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0256 0.0222 0.2413
Brugia malayi Protein kinase domain containing protein 0.0325 0.033 0.0319
Echinococcus granulosus N chimaerin 0.0161 0.0074 0.0146
Loa Loa (eye worm) hypothetical protein 0.0122 0.0012 0.0001
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0256 0.0222 0.0613
Echinococcus multilocularis tyrosine protein kinase Srms 0.0303 0.0296 0.0519
Schistosoma mansoni serine/threonine protein kinase 0.0553 0.0686 0.2139
Entamoeba histolytica protein kinase, putative 0.0196 0.0128 0.0488
Schistosoma mansoni protein kinase 0.1073 0.15 0.4689
Entamoeba histolytica cell division protein kinase 2, putative 0.0742 0.0982 0.3738
Trichomonas vaginalis CMGC family protein kinase 0.0216 0.0159 0.173
Entamoeba histolytica protein kinase, putative 0.0179 0.0101 0.0383
Echinococcus granulosus Cell division cycle 2 protein kinase 0.0137 0.0035 0.0024
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0702 0.0919 1
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0256 0.0222 0.0376
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0183 0.0108 0.117
Trichomonas vaginalis CAMK family protein kinase 0.0364 0.039 0.4243
Loa Loa (eye worm) hypothetical protein 0.0343 0.0357 0.0347
Schistosoma mansoni hypothetical protein 0.0201 0.0136 0.0416
Echinococcus granulosus tyrosine protein kinase Src42A 0.0217 0.016 0.0418
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.1144 0.1611 0.1603
Echinococcus granulosus titin 0.0148 0.0053 0.008
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0325 0.033 0.032
Trichomonas vaginalis CAMK family protein kinase 0.0364 0.039 0.4243
Brugia malayi protein unc-22 0.0148 0.0053 0.0042
Echinococcus granulosus activin receptor type 0.0559 0.0695 0.2108
Toxoplasma gondii CMGC kinase, CK2 family 0.0172 0.0091 0.0986
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0183 0.0108 0.117
Brugia malayi bone morphogenetic protein type 1 receptor 0.0164 0.0077 0.0067
Loa Loa (eye worm) CMGC/GSK protein kinase 0.067 0.087 0.086
Echinococcus multilocularis mitogen activated protein kinase 0.0154 0.0062 0.0066
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0136 0.0034 0.0024
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0203 0.0139 0.0215
Trichomonas vaginalis CAMK family protein kinase 0.0183 0.0108 0.117
Schistosoma mansoni serine/threonine protein kinase 0.0326 0.0331 0.1025
Brugia malayi Protein kinase domain containing protein 0.0299 0.029 0.0279
Loa Loa (eye worm) casein kinase 0.0203 0.0139 0.0128
Loa Loa (eye worm) TK/FAK protein kinase 0.035 0.0369 0.0359
Entamoeba histolytica hypothetical protein 0.0553 0.0686 0.2612
Plasmodium vivax serine/threonine protein kinase 6, putative 0.028 0.026 0.2823
Brugia malayi probable protein kinase 0.102 0.1417 0.1408
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0517 0.063 0.062
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0321 0.0324 0.0572
Loa Loa (eye worm) CMGC/GSK protein kinase 0.067 0.087 0.086
Trichomonas vaginalis CAMK family protein kinase 0.0202 0.0137 0.1489
Echinococcus granulosus casein kinase I alpha 0.0294 0.0282 0.0802
Echinococcus multilocularis 0.0633 0.0811 0.1514
Schistosoma mansoni serine/threonine protein kinase 0.0701 0.0919 0.2867
Trichomonas vaginalis STE family protein kinase 0.0203 0.0139 0.151
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.1875 0.2755 0.5272
Brugia malayi Protein kinase domain containing protein 0.1144 0.1611 0.1603
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0344 0.0359 0.1046
Brugia malayi Protein kinase domain containing protein 0.0156 0.0066 0.0055
Trichomonas vaginalis CAMK family protein kinase 0.0183 0.0108 0.117
Loa Loa (eye worm) AGC/AKT protein kinase 0.0459 0.054 0.0529
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0151 0.0058 0.0096
Echinococcus granulosus insulin receptor 0.0676 0.0879 0.2686
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0553 0.0686 0.0676
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0036 0.0391
Loa Loa (eye worm) hypothetical protein 0.0456 0.0535 0.0525
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0487 0.0584 0.0574
Trichomonas vaginalis serine/threonine kinase, putative 0.0137 0.0035 0.0384
Echinococcus granulosus calcium dependent protein kinase 0.0159 0.0071 0.0136
Brugia malayi Protein kinase domain containing protein 0.0302 0.0294 0.0284
Leishmania major protein kinase, putative 0.0701 0.0919 0.9993
Plasmodium falciparum NIMA related kinase 2 0.0117 0.0004 0.0041
Giardia lamblia Kinase, CMGC GSK 0.067 0.087 0.9458
Brugia malayi Protein kinase domain containing protein 0.0285 0.0268 0.0257
Brugia malayi casein kinase 1, delta 0.0294 0.0282 0.0271
Onchocerca volvulus 0.1033 0.1438 0.4407
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0214 0.0156 0.0248
Schistosoma mansoni protein kinase 0.0187 0.0115 0.0347
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0303 0.0296 0.0848
Loa Loa (eye worm) TK/FER protein kinase 0.0175 0.0095 0.0084
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0565 0.0705 0.1309
Schistosoma mansoni tyrosine kinase 0.0552 0.0685 0.2133
Echinococcus granulosus TGF-beta receptor type-1 0.0169 0.0086 0.0185
Echinococcus multilocularis casein kinase I delta 0.0294 0.0282 0.0491
Entamoeba histolytica protein kinase domain containing protein 0.0326 0.0331 0.1259
Giardia lamblia Kinase, CDC7 0.0665 0.0862 0.9367
Echinococcus granulosus TGF beta receptor type 1 0.0169 0.0086 0.0185
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0565 0.0705 0.2137
Trichomonas vaginalis CAMK family protein kinase 0.0183 0.0108 0.117
Onchocerca volvulus 0.0149 0.0054 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0381 0.0418 0.1297
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0662 0.0857 0.1603
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0387 0.0427 0.0772
Echinococcus multilocularis Glutaredoxin protein 5 0.0139 0.0039 0.0022
Trypanosoma cruzi casein kinase, putative 0.0294 0.0282 0.3065
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0484 0.0578 0.1065
Loa Loa (eye worm) TK/FER protein kinase 0.0175 0.0095 0.0084
Echinococcus granulosus casein kinase I gamma 0.0299 0.029 0.0827
Brugia malayi STE20-like kinase MST 0.0762 0.1014 0.1004
Schistosoma mansoni adapter molecule crk 0.0136 0.0034 0.0095
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0216 0.0159 0.173
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Trichomonas vaginalis G protein-coupled receptor kinase, putative 0.0137 0.0035 0.0384
Plasmodium falciparum calcium-dependent protein kinase 2 0.0256 0.0222 0.2413
Schistosoma mansoni tyrosine kinase 0.0347 0.0364 0.1129
Echinococcus granulosus aurora kinase A 0.028 0.026 0.0732
Schistosoma mansoni protein kinase 0.1073 0.15 0.4689
Schistosoma mansoni serine/threonine-protein kinase 0.0253 0.0218 0.067
Trypanosoma cruzi aurora B kinase, putative 0.028 0.026 0.2823
Onchocerca volvulus Serine\/threonine kinase homolog 0.0364 0.039 0.1073
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0487 0.0583 0.0573
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0387 0.0427 0.4646
Loa Loa (eye worm) hypothetical protein 0.0726 0.0957 0.0947
Leishmania major protein kinase, putative 0.0256 0.0222 0.2413
Leishmania major protein kinase, putative 0.0187 0.0115 0.1247
Trichomonas vaginalis STE family protein kinase 0.0247 0.0207 0.2256
Loa Loa (eye worm) hypothetical protein 0.0175 0.0095 0.0084
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0433 0.0499 0.0911
Echinococcus multilocularis protein kinase shaggy 0.067 0.087 0.1628
Plasmodium falciparum calcium-dependent protein kinase 3 0.0256 0.0222 0.2413
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0154 0.0062 0.0673
Trichomonas vaginalis STE family protein kinase 0.025 0.0213 0.2317
Trichomonas vaginalis CAMK family protein kinase 0.0364 0.039 0.4243
Schistosoma mansoni serine/threonine protein kinase 0.1916 0.282 0.8822
Trichomonas vaginalis AGC family protein kinase 0.012 0.0008 0.0092
Loa Loa (eye worm) hypothetical protein 0.0605 0.0768 0.0758
Echinococcus granulosus fibroblast growth factor receptor 4 0.0414 0.0469 0.1394
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0564 0.0704 0.0694
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0154 0.0062 0.0673
Echinococcus granulosus hypothetical protein 0.0605 0.0768 0.2336
Echinococcus granulosus cyclin dependent kinase 1 0.0702 0.0919 0.2815
Onchocerca volvulus 0.067 0.087 0.2599
Echinococcus multilocularis cyclin dependent kinase 0.0702 0.0919 0.1724
Toxoplasma gondii histone kinase SNF1, putative 0.0183 0.0108 0.117
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0153 0.0061 0.066
Echinococcus granulosus tyrosine kinase 0.0303 0.0296 0.0848
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.1073 0.15 0.2847
Loa Loa (eye worm) CAMK/PIM protein kinase 0.1875 0.2755 0.2747
Echinococcus granulosus tyrosine protein kinase Fyn 0.0356 0.0378 0.1105
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0616 0.0785 0.239
Giardia lamblia Kinase, CMGC CLK 0.0701 0.0919 0.9993
Echinococcus multilocularis c src tyrosine kinase 0.0227 0.0176 0.0288
Entamoeba histolytica PH domain containing protein kinase, putative 0.0679 0.0883 0.3361
Trichomonas vaginalis CMGC family protein kinase 0.0154 0.0062 0.0673
Brugia malayi cyclin-dependent kinase 7 homolog 0.0528 0.0647 0.0637
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0223 0.017 0.1853
Loa Loa (eye worm) gastrulation defective protein 1 0.039 0.0431 0.0421
Echinococcus multilocularis serine:threonine protein kinase 3 0.0762 0.1014 0.1907
Schistosoma mansoni serine/threonine protein kinase 0.0469 0.0555 0.1728
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0517 0.063 0.062
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0389 0.043 0.0778
Echinococcus multilocularis casein kinase i 0.0294 0.0282 0.0491
Brugia malayi hypothetical protein 0.0204 0.014 0.0129
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0154 0.0062 0.0673
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0503 0.0608 0.1122
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0364 0.039 0.4243
Toxoplasma gondii NEK kinase 0.0117 0.0004 0.0041
Trypanosoma brucei protein kinase, putative 0.0194 0.0125 0.1356
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.028 0.026 0.0988
Entamoeba histolytica casein kinase, putative 0.0172 0.0091 0.0345
Loa Loa (eye worm) hypothetical protein 0.0234 0.0188 0.0177
Loa Loa (eye worm) TK/ALK protein kinase 0.0877 0.1194 0.1184
Brugia malayi Protein kinase domain containing protein 0.0734 0.097 0.0961
Giardia lamblia Kinase, CMGC CDK 0.0702 0.0919 1
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0784 0.1048 0.1973
Schistosoma mansoni growth factor receptor-bound protein 0.014 0.004 0.0114
Loa Loa (eye worm) hypothetical protein 0.022 0.0166 0.0155
Trichomonas vaginalis CAMK family protein kinase 0.0183 0.0108 0.117
Echinococcus multilocularis epidermal growth factor receptor 0.0552 0.0685 0.127
Loa Loa (eye worm) hypothetical protein 0.0297 0.0285 0.0275
Echinococcus multilocularis activated cdc42 kinase 1 0.0259 0.0226 0.0384
Schistosoma mansoni serine/threonine protein kinase 0.0227 0.0176 0.054
Brugia malayi ephrin receptor 1 precursor 0.0125 0.0017 0.0006
Echinococcus multilocularis myosin iiia 0.025 0.0213 0.0358
Brugia malayi intracellular kinase 0.067 0.087 0.086
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0036 0.0391
Echinococcus granulosus ephrin type A receptor 4 A 0.0163 0.0076 0.0153
Schistosoma mansoni ste20-related kinase 0.0609 0.0774 0.2412
Brugia malayi RhoGAP domain containing protein 0.0161 0.0074 0.0063
Loa Loa (eye worm) hypothetical protein 0.0193 0.0123 0.0113
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.1144 0.1611 0.3062
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Echinococcus multilocularis tyrosine kinase 0.0175 0.0095 0.013
Brugia malayi Protein kinase domain containing protein 0.0175 0.0095 0.0084
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0227 0.0176 0.0166
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.025 0.0213 0.0811
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0263 0.0233 0.0223
Schistosoma mansoni serine/threonine protein kinase 0.0426 0.0487 0.1515
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0616 0.0784 0.1463
Trypanosoma cruzi casein kinase II, putative 0.0172 0.0091 0.0986
Echinococcus multilocularis serine:threonine protein kinase NLK 0.0137 0.0035 0.0015
Echinococcus multilocularis TGF beta receptor type 1 0.0169 0.0086 0.0113
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.6505 1 1
Trichomonas vaginalis CMGC family protein kinase 0.0216 0.0159 0.173
Schistosoma mansoni serine/threonine kinase 0.0675 0.0877 0.2736
Schistosoma mansoni tyrosine kinase 0.0552 0.0685 0.2133
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0553 0.0686 0.7465
Brugia malayi serine/threonine-protein kinase plk-2 0.0364 0.039 0.038
Trichomonas vaginalis AGC family protein kinase 0.028 0.026 0.2823
Loa Loa (eye worm) hypothetical protein 0.0923 0.1266 0.1256
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0701 0.0919 0.9993
Brugia malayi Protein kinase domain containing protein 0.0702 0.0919 0.091
Schistosoma mansoni serine/threonine protein kinase 0.0344 0.0359 0.1113
Trichomonas vaginalis CMGC family protein kinase 0.0701 0.0919 0.9993
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0553 0.0686 0.7465
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Echinococcus multilocularis hypothetical protein 0.0201 0.0136 0.021
Schistosoma mansoni protein kinase 0.0187 0.0115 0.0347
Echinococcus granulosus tyrosine protein kinase ABL1 0.0408 0.046 0.1365
Trypanosoma brucei Serine/threonine-protein kinase NEK16, putative 0.0117 0.0004 0.0041
Schistosoma mansoni protein kinase 0.0187 0.0115 0.0347
Brugia malayi SRC-1 0.0356 0.0378 0.0367
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0161 0.0074 0.0063
Loa Loa (eye worm) hypothetical protein 0.0183 0.0108 0.0097
Schistosoma mansoni vam6/vps39 related 0.0387 0.0427 0.1327
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0426 0.0487 0.0889
Onchocerca volvulus 0.0667 0.0865 0.2585
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0153 0.0061 0.066
Trichomonas vaginalis CK1 family protein kinase 0.0294 0.0282 0.3065
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0183 0.0108 0.0155
Entamoeba histolytica protein kinase, putative 0.067 0.087 0.331
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0356 0.0378 0.0676
Echinococcus multilocularis protein KINase family member (kin 25) 0.0156 0.0065 0.0072
Loa Loa (eye worm) hypothetical protein 0.0519 0.0633 0.0623
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0661 0.0856 0.2614
Trichomonas vaginalis CAMK family protein kinase 0.0364 0.039 0.4243
Brugia malayi protein kinase C II. 0.0381 0.0418 0.0407
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0302 0.0294 0.0842
Schistosoma mansoni tyrosine kinase 0.0324 0.0328 0.1017
Schistosoma mansoni serine/threonine protein kinase 0.0183 0.0108 0.0325
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0216 0.0159 0.173
Leishmania major protein kinase, putative 0.0117 0.0004 0.0041
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0326 0.0331 0.0321
Entamoeba histolytica PH domain containing protein kinase, putative 0.0679 0.0883 0.3361
Echinococcus multilocularis insulin receptor 0.0676 0.0879 0.1645
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0214 0.0156 0.0145
Plasmodium vivax serine/threonine-protein kinase NEK4, putative 0.0117 0.0004 0.0041
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0216 0.0159 0.173
Loa Loa (eye worm) hypothetical protein 0.0201 0.0136 0.0126
Loa Loa (eye worm) hypothetical protein 0.018 0.0103 0.0092
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0154 0.0062 0.0673
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0175 0.0095 0.0085
Echinococcus multilocularis raf serine:threonine protein kinase 0.0168 0.0084 0.011
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0247 0.0207 0.2256
Brugia malayi C1-like domain containing protein 0.0517 0.063 0.062
Trichomonas vaginalis AGC family protein kinase 0.0459 0.054 0.5867
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0552 0.0685 0.2074
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Brugia malayi cyclin-dependent kinase 9 0.0326 0.0331 0.0321
Loa Loa (eye worm) hypothetical protein 0.0387 0.0427 0.0417
Giardia lamblia Kinase, CMGC MAPK 0.0154 0.0062 0.0634
Entamoeba histolytica protein kinase, putative 0.0139 0.0039 0.0149
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0244 0.0203 0.034
Echinococcus multilocularis NCK adaptor protein 0.014 0.004 0.0024
Echinococcus granulosus protein tyrosine kinase 0.0347 0.0364 0.1063
Echinococcus multilocularis calcium activated potassium channel 0.0298 0.0288 0.0503
Trypanosoma cruzi casein kinase, putative 0.0294 0.0282 0.3065
Echinococcus granulosus tyrosine protein kinase HCK 0.0219 0.0165 0.0433
Echinococcus multilocularis casein kinase ii subunit alpha 0.0172 0.0091 0.0122
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0256 0.0222 0.2413
Entamoeba histolytica casein kinase 1, putative 0.0294 0.0282 0.1072
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0175 0.0095 0.0361
Schistosoma mansoni growth factor receptor-bound protein 0.0136 0.0034 0.0095
Echinococcus granulosus defective proboscis extension response 0.0193 0.0123 0.0302
Trichomonas vaginalis CMGC family protein kinase 0.067 0.087 0.946
Onchocerca volvulus 0.0175 0.0095 0.0133
Echinococcus multilocularis casein kinase I delta 0.0294 0.0282 0.0491
Schistosoma mansoni serine/threonine protein kinase 0.1794 0.2628 0.8221
Brugia malayi phosphoinositide-dependent protein kinase I 0.0151 0.0058 0.0047
Schistosoma mansoni serine/threonine protein kinase 0.0661 0.0856 0.2669
Entamoeba histolytica PH domain containing protein kinase, putative 0.0253 0.0218 0.0828
Echinococcus granulosus roundabout 2 0.0272 0.0246 0.069
Brugia malayi serine/threonine kinase 12 0.028 0.026 0.0249
Loa Loa (eye worm) hypothetical protein 0.0259 0.0226 0.0216
Trichomonas vaginalis CK1 family protein kinase 0.0294 0.0282 0.3065
Brugia malayi Protein kinase domain containing protein 0.0308 0.0303 0.0292
Brugia malayi Protein kinase domain 0.0203 0.0139 0.0128
Loa Loa (eye worm) hypothetical protein 0.0168 0.0084 0.0074
Trichomonas vaginalis CAMK family protein kinase 0.0183 0.0108 0.117
Loa Loa (eye worm) TK/FER protein kinase 0.0175 0.0095 0.0084
Schistosoma mansoni serine/threonine protein kinase 0.0389 0.043 0.1335
Echinococcus granulosus neuroglian 0.0234 0.0188 0.0505
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0591 0.0746 0.0736
Onchocerca volvulus 0.0665 0.0862 0.2573
Echinococcus granulosus tyrosine protein kinase Blk 0.0303 0.0296 0.0848
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0302 0.0294 0.0516
Brugia malayi Doublecortin family protein 0.0229 0.018 0.0169
Brugia malayi hypothetical protein 0.0175 0.0095 0.0084
Trichomonas vaginalis AGC family protein kinase 0.0459 0.054 0.5867
Trichomonas vaginalis AGC family protein kinase 0.028 0.026 0.2823
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0276 0.0254 0.0243
Entamoeba histolytica hypothetical protein 0.0427 0.049 0.1865
Echinococcus granulosus serine:threonine protein kinase 12 B 0.028 0.026 0.0732
Entamoeba histolytica cell division protein kinase 2, putative 0.0702 0.0919 0.3499
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0387 0.0427 0.1261
Echinococcus multilocularis expressed conserved protein 0.0211 0.0151 0.0239
Brugia malayi Sex muscle abnormal protein 5 0.0136 0.0034 0.0024
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0414 0.0469 0.0854
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0356 0.0378 0.0676
Brugia malayi protein-tyrosine kinase 0.0303 0.0296 0.0286
Brugia malayi Protein kinase domain containing protein 0.0175 0.0095 0.0084
Schistosoma mansoni protein kinase 0.0203 0.0139 0.0423
Schistosoma mansoni serine/threonine protein kinase 0.0344 0.0359 0.1113
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0661 0.0856 0.9307
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0203 0.0139 0.0351
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0203 0.0139 0.0351
Loa Loa (eye worm) TK protein kinase 0.0303 0.0296 0.0286
Loa Loa (eye worm) hypothetical protein 0.0438 0.0506 0.0496
Schistosoma mansoni serine/threonine protein kinase 0.0702 0.0919 0.2869
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0866 0.1176 0.1167
Giardia lamblia Kinase, CK1 Casein kinase 0.0294 0.0282 0.3036
Loa Loa (eye worm) AGC/NDR protein kinase 0.0302 0.0294 0.0284
Plasmodium vivax serine/threonine kinase-1, putative 0.0701 0.0919 0.9993
Echinococcus multilocularis dual specificity mitogen activated protein 0.0247 0.0207 0.0348
Giardia lamblia Kinase, CMGC GSK 0.067 0.087 0.9458
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0302 0.0294 0.0516
Schistosoma mansoni serine/threonine protein kinase 0.0302 0.0294 0.0911
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0236 0.019 0.0513
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0153 0.0061 0.066
Brugia malayi Protein kinase domain containing protein 0.0665 0.0862 0.0852
Entamoeba histolytica protein kinase domain containing protein 0.0216 0.0159 0.0605
Brugia malayi Protein kinase domain containing protein 0.0259 0.0226 0.0216
Brugia malayi protein kinase C3,putative 0.0267 0.0239 0.0229
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0148 0.0053 0.0042
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0256 0.0222 0.0376
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0344 0.0359 0.0641
Brugia malayi Protein kinase domain containing protein 0.0244 0.0203 0.0193
Plasmodium falciparum protein kinase, putative 0.0187 0.0115 0.1247
Loa Loa (eye worm) TK/FER protein kinase 0.0175 0.0095 0.0084
Loa Loa (eye worm) hypothetical protein 0.0599 0.0758 0.0749
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0256 0.0222 0.0613
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0036 0.0391
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0661 0.0856 0.9307
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.067 0.087 0.946
Trypanosoma cruzi Mitogen-activated protein kinase 10, putative 0.0137 0.0035 0.0384
Entamoeba histolytica serine/threonine protein kinase, putative 0.0183 0.0108 0.0409
Trichomonas vaginalis CMGC family protein kinase 0.0216 0.0159 0.173
Echinococcus granulosus tyrosine protein kinase Fyn 0.0356 0.0378 0.1105
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0203 0.0139 0.0351
Echinococcus multilocularis Immunoglobulin 0.0193 0.0123 0.0185
Trypanosoma brucei SNF1-related protein kinases, putative 0.0183 0.0108 0.117
Schistosoma mansoni serine/threonine protein kinase 0.2157 0.3196 1
Schistosoma mansoni serine/threonine protein kinase 0.0183 0.0108 0.0325
Echinococcus multilocularis mitogen activated protein kinase 11 0.0366 0.0394 0.0709
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0702 0.0919 0.091
Brugia malayi Immunoglobulin I-set domain containing protein 0.0148 0.0053 0.0042
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0187 0.0115 0.1247
Trichomonas vaginalis CAMK family protein kinase 0.0117 0.0004 0.0041
Brugia malayi Tyrosine-protein kinase abl-1 0.0144 0.0047 0.0036
Trichomonas vaginalis AGC family protein kinase 0.012 0.0008 0.0092
Trichomonas vaginalis AGC family protein kinase 0.012 0.0008 0.0092
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0469 0.0555 0.102
Trypanosoma cruzi casein kinase, putative 0.0294 0.0282 0.3065
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0203 0.0139 0.0215
Trichomonas vaginalis CAMK family protein kinase 0.0183 0.0108 0.117
Brugia malayi Cell division protein kinase 2 0.0137 0.0035 0.0025
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0211 0.0151 0.0239
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.1875 0.2755 0.8597
Echinococcus multilocularis dual specificity protein kinase clk2 0.0701 0.0919 0.1723
Loa Loa (eye worm) hypothetical protein 0.0374 0.0406 0.0396
Echinococcus multilocularis serine:threonine protein kinase 38 0.0302 0.0294 0.0516
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0702 0.0919 0.091
Brugia malayi Fes/CIP4 homology domain containing protein 0.0351 0.037 0.036
Echinococcus multilocularis serine:threonine protein kinase N2 0.0531 0.0653 0.1208
Schistosoma mansoni vesicular amine transporter 0.0193 0.0123 0.0375
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Echinococcus granulosus serine:threonine protein kinase N2 0.0834 0.1126 0.3466
Echinococcus granulosus protein kinase 0.0633 0.0811 0.2473
Plasmodium vivax protein kinase Crk2 0.0702 0.0919 1
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.1875 0.2755 0.8609
Loa Loa (eye worm) hypothetical protein 0.0204 0.014 0.0129
Echinococcus granulosus serine threonine protein kinase nrc 0.0236 0.019 0.0513
Loa Loa (eye worm) hypothetical protein 0.0605 0.0768 0.0758
Echinococcus granulosus growth factor receptor bound protein 2 0.014 0.004 0.004
Echinococcus multilocularis Cell division cycle 2 protein kinase 0.0137 0.0035 0.0015
Trichomonas vaginalis CAMK family protein kinase 0.0117 0.0004 0.0041
Schistosoma mansoni serine/threonine protein kinase 0.0183 0.0108 0.0325
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0734 0.097 0.0961
Echinococcus multilocularis cyclin dependent kinase 9 0.0366 0.0394 0.0708
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Brugia malayi Protein kinase c protein 2 0.022 0.0165 0.0155
Onchocerca volvulus 0.0343 0.0357 0.0969
Schistosoma mansoni serine/threonine protein kinase 0.0216 0.0159 0.0487
Loa Loa (eye worm) TK/EPH protein kinase 0.0183 0.0107 0.0096
Brugia malayi Variant SH3 domain containing protein 0.0161 0.0074 0.0063
Brugia malayi Homeodomain interacting protein kinase protein 1 0.1794 0.2628 0.262
Schistosoma mansoni protein kinase 0.0203 0.0139 0.0423
Brugia malayi Stress-activated protein kinase jnk-1 0.0591 0.0746 0.0736
Echinococcus multilocularis dual specificity 0.0216 0.0159 0.0254
Trypanosoma brucei protein kinase, putative 0.067 0.087 0.946
Trichomonas vaginalis CMGC family protein kinase 0.0216 0.0159 0.173
Echinococcus multilocularis casein kinase I alpha 0.0294 0.0282 0.0491
Loa Loa (eye worm) hypothetical protein 0.0734 0.097 0.0961
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0633 0.0811 0.0801
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0156 0.0066 0.0074
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0702 0.0919 0.2815
Echinococcus granulosus dual specificity mitogen activated protein 0.0247 0.0207 0.0568
Trichomonas vaginalis AGC family protein kinase 0.0325 0.033 0.3593
Entamoeba histolytica protein kinase domain containing protein 0.0172 0.0091 0.0345
Trichomonas vaginalis AGC family protein kinase 0.012 0.0008 0.0092
Echinococcus granulosus tyrosine protein kinase shark 0.081 0.1088 0.3348
Trichomonas vaginalis AGC family protein kinase 0.028 0.026 0.2823
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0441 0.0512 0.0502
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0036 0.0391
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0256 0.0222 0.0211
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0214 0.0156 0.0145
Trypanosoma cruzi casein kinase, putative 0.0294 0.0282 0.3065
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0214 0.0156 0.0145
Plasmodium falciparum casein kinase 1 0.0294 0.0282 0.3065
Schistosoma mansoni tyrosine kinase 0.0786 0.1051 0.3281
Echinococcus granulosus protein kinase shaggy 0.067 0.087 0.2659
Schistosoma mansoni vav2 0.0179 0.0101 0.0305
Entamoeba histolytica protein kinase, putative 0.0459 0.054 0.2053
Giardia lamblia Kinase, CMGC CDK 0.0702 0.0919 1
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Schistosoma mansoni serine/threonine protein kinase 0.0299 0.029 0.0896
Brugia malayi Serine/threonine-protein kinase Pim-3 0.1875 0.2755 0.2747
Echinococcus multilocularis neuropeptide s receptor 0.0558 0.0695 0.129
Echinococcus granulosus casein kinase I delta 0.0294 0.0282 0.0802
Schistosoma mansoni kinase 0.0384 0.0423 0.1312
Trichomonas vaginalis CAMK family protein kinase 0.0183 0.0108 0.117
Trichomonas vaginalis CAMK family protein kinase 0.0183 0.0108 0.117
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0143 0.0044 0.0034
Brugia malayi Protein kinase domain containing protein 0.0325 0.033 0.032
Loa Loa (eye worm) hypothetical protein 0.0261 0.023 0.0219
Loa Loa (eye worm) TK protein kinase 0.0219 0.0165 0.0154
Trichomonas vaginalis CMGC family protein kinase 0.0665 0.0862 0.937
Echinococcus granulosus mitogen activated protein kinase 0.0154 0.0062 0.0108
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0191 0.0121 0.011
Brugia malayi Temporarily assigned gene name protein 59 0.0387 0.0427 0.0417
Trichomonas vaginalis AGC family protein kinase 0.0325 0.033 0.3593
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0762 0.1014 0.1004
Schistosoma mansoni tyrosine kinase 0.081 0.1088 0.3398
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0229 0.018 0.0169
Loa Loa (eye worm) AUR protein kinase 0.028 0.026 0.0249
Echinococcus granulosus calcium activated potassium channel 0.0298 0.0288 0.0821
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0193 0.0123 0.0185
Onchocerca volvulus 0.0175 0.0095 0.0133
Loa Loa (eye worm) TK/FER protein kinase 0.0175 0.0095 0.0084
Schistosoma mansoni serine/threonine protein kinase 0.0298 0.0288 0.0889
Schistosoma mansoni protein kinase 0.0294 0.0282 0.0871
Trichomonas vaginalis CMGC family protein kinase 0.0137 0.0035 0.0384
Leishmania major protein kinase, putative 0.0701 0.0919 0.9993
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0923 0.1266 0.3908
Entamoeba histolytica protein kinase, putative 0.0139 0.0039 0.0149
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0036 0.0391
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0701 0.0919 0.9993
Entamoeba histolytica protein kinase, putative 0.028 0.026 0.0988
Echinococcus multilocularis cyclin dependent kinase 19 0.0487 0.0583 0.1073
Echinococcus granulosus tyrosine protein kinase Fyn 0.0356 0.0378 0.1105
Echinococcus granulosus neuropeptide receptor A26 0.0558 0.0695 0.2107
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0387 0.0427 0.4646
Plasmodium falciparum protein kinase 5 0.0702 0.0919 1
Giardia lamblia Kinase, CAMK CAMKL 0.0223 0.017 0.182
Trichomonas vaginalis serine/threonine-protein kinase ypk, putative 0.012 0.0008 0.0092
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0161 0.0074 0.0089
Giardia lamblia Kinase, CMGC SRPK 0.0153 0.0061 0.0622
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0229 0.0179 0.1948
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0734 0.097 0.0961
Giardia lamblia Kinase, NEK 0.0213 0.0154 0.1642
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0117 0.0004 0.0041
Echinococcus multilocularis casein kinase I alpha 0.0294 0.0282 0.0491
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0978 0.1352 0.1343
Brugia malayi Protein kinase domain containing protein 0.0153 0.0061 0.005
Brugia malayi SH2 domain containing protein 0.0321 0.0324 0.0313
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0035 0.0384
Plasmodium vivax glycogen synthase kinase 3, putative 0.067 0.087 0.946
Schistosoma mansoni serine/threonine protein kinase 0.0661 0.0856 0.2669
Echinococcus granulosus mitogen activated protein kinase 11 0.0366 0.0394 0.1158
Schistosoma mansoni tyrosine kinase 0.0173 0.0092 0.0275
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Echinococcus granulosus casein kinase I delta 0.0294 0.0282 0.0802
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0294 0.0282 0.0271
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0356 0.0378 0.0676
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0172 0.0091 0.008
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0036 0.0391
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0321 0.0324 0.0935
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0256 0.0222 0.0211
Trichomonas vaginalis AGC family protein kinase 0.012 0.0008 0.0092
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0256 0.0222 0.2413
Trichomonas vaginalis AGC family protein kinase 0.012 0.0008 0.0092
Loa Loa (eye worm) TK/ROR protein kinase 0.0132 0.0028 0.0017
Loa Loa (eye worm) hypothetical protein 0.0261 0.023 0.0219
Trichomonas vaginalis AGC family protein kinase 0.0343 0.0357 0.3885
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0187 0.0115 0.1247
Echinococcus granulosus casein kinase ii subunit alpha 0.0172 0.0091 0.0199
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0193 0.0123 0.0375
Loa Loa (eye worm) hypothetical protein 0.0134 0.0031 0.002
Schistosoma mansoni serine/threonine protein kinase 0.0501 0.0605 0.1884
Schistosoma mansoni serine/threonine protein kinase 0.0665 0.0862 0.2687
Giardia lamblia Kinase, STE STE20 0.0203 0.0139 0.1475
Loa Loa (eye worm) CMGC/CDK/CRK7 protein kinase 0.0137 0.0035 0.0025
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0213 0.0154 0.1676
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0686 0.0895 0.1676
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.028 0.026 0.0988
Brugia malayi Protein kinase domain containing protein 0.0487 0.0583 0.0573
Brugia malayi Protein kinase domain containing protein 0.0142 0.0044 0.0033
Loa Loa (eye worm) AUR protein kinase 0.028 0.026 0.0249
Schistosoma mansoni titin 0.0148 0.0053 0.0154
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0139 0.0039 0.0036
Echinococcus multilocularis serine:threonine protein kinase N2 0.0834 0.1126 0.2123
Schistosoma mansoni serine/threonine protein kinase 0.0148 0.0053 0.0154
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0036 0.0391
Trichomonas vaginalis AGC family protein kinase 0.012 0.0008 0.0092
Schistosoma mansoni protein kinase 0.1144 0.1611 0.5037
Echinococcus granulosus epidermal growth factor receptor 0.0552 0.0685 0.2074
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0387 0.0427 0.4646
Entamoeba histolytica protein kinase domain containing protein 0.067 0.087 0.331
Echinococcus multilocularis serine threonine protein kinase 0.0348 0.0366 0.0655
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0387 0.0427 0.1327
Schistosoma mansoni protein kinase 0.0164 0.0077 0.023
Entamoeba histolytica protein kinase domain containing protein 0.067 0.087 0.331
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0139 0.0039 0.0022
Trichomonas vaginalis AGC family protein kinase 0.012 0.0008 0.0092
Schistosoma mansoni serine/threonine protein kinase 0.0487 0.0584 0.1818
Trichomonas vaginalis AGC family protein kinase 0.0151 0.0058 0.0629
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0036 0.0391
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0661 0.0856 0.0846
Echinococcus multilocularis tyrosine protein kinase Blk 0.0303 0.0296 0.0519
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0211 0.0151 0.1646
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0247 0.0207 0.2256
Giardia lamblia Kinase, NEK 0.0213 0.0154 0.1642
Echinococcus granulosus NDR protein kinase 0.0302 0.0294 0.0842
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0356 0.0378 0.0676
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0356 0.0378 0.0676
Brugia malayi serine/threonine protein kinase 6 0.028 0.026 0.0249
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0701 0.0919 0.9993
Plasmodium falciparum cGMP-dependent protein kinase 0.0211 0.0151 0.1646
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0187 0.0115 0.1247
Brugia malayi Protein kinase domain containing protein 0.0159 0.0069 0.0059
Trichomonas vaginalis AGC family protein kinase 0.012 0.0008 0.0092
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0154 0.0062 0.0051
Trichomonas vaginalis CAMK family protein kinase 0.0404 0.0453 0.4926
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0247 0.0207 0.2256
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0236 0.019 0.2068
Echinococcus granulosus nervana 2 0.0139 0.0039 0.0036
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0198 0.0131 0.142
Schistosoma mansoni tyrosine kinase 0.0461 0.0542 0.1688
Loa Loa (eye worm) TK/FER protein kinase 0.0321 0.0324 0.0313
Brugia malayi Serine/threonine-protein kinase SULU 0.0501 0.0605 0.0595
Onchocerca volvulus 0.0294 0.0282 0.0728
Schistosoma mansoni tyrosine kinase 0.0461 0.0542 0.1688
Schistosoma mansoni serine/threonine protein kinase 0.0183 0.0108 0.0325
Loa Loa (eye worm) hypothetical protein 0.0256 0.0222 0.0211
Onchocerca volvulus 0.0175 0.0095 0.0133
Echinococcus multilocularis twitchin 0.0138 0.0037 0.0018
Trypanosoma brucei Casein kinase II 0.0172 0.0091 0.0986
Plasmodium vivax serine/threonine-protein kinase Nek1, putative 0.0117 0.0004 0.0041
Trichomonas vaginalis AGC family protein kinase 0.0213 0.0154 0.1676
Schistosoma mansoni serine/threonine protein kinase 0.0294 0.0282 0.0871
Loa Loa (eye worm) hypothetical protein 0.0456 0.0535 0.0525
Trichomonas vaginalis AGC family protein kinase 0.012 0.0008 0.0092
Trichomonas vaginalis CAMK family protein kinase 0.0183 0.0108 0.117
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0366 0.0394 0.4288
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0035 0.0384
Toxoplasma gondii NEK kinase 0.0117 0.0004 0.0041
Loa Loa (eye worm) AGC/PKG protein kinase 0.0211 0.0151 0.0141
Plasmodium falciparum MO15-related protein kinase 0.0137 0.0035 0.0384
Trypanosoma cruzi Protein kinase B 0.0253 0.0218 0.2367
Echinococcus granulosus rho-associated protein kinase 1 0.2157 0.3196 1
Giardia lamblia Kinase, STE STE20 0.025 0.0213 0.2285
Schistosoma mansoni rap gtpase-activating protein 0.0387 0.0427 0.1327
Brugia malayi Egg laying defective protein 4 0.0211 0.0151 0.0141
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0117 0.0004 0.0041
Mycobacterium ulcerans hypothetical protein 0.0114 0 0.5
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0035 0.0384
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0616 0.0785 0.1463
Brugia malayi Protein kinase domain containing protein 0.0701 0.0919 0.0909
Schistosoma mansoni serine/threonine protein kinase 0.0661 0.0856 0.2669
Echinococcus granulosus c src tyrosine kinase 0.0227 0.0176 0.0469
Schistosoma mansoni serine/threonine protein kinase 0.0151 0.0058 0.017
Trichomonas vaginalis CAMK family protein kinase 0.0117 0.0004 0.0041
Echinococcus granulosus Vam6:Vps39 protein 0.0387 0.0427 0.1261
Echinococcus multilocularis serine:threonine protein kinase 0.0142 0.0044 0.0032
Loa Loa (eye worm) TK/ABL protein kinase 0.0408 0.046 0.045
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0381 0.0418 0.0407
Echinococcus multilocularis serine:threonine protein kinase 0.0142 0.0044 0.0032
Echinococcus multilocularis casein kinase I gamma 0.0299 0.029 0.0507
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0227 0.0176 0.0541
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Schistosoma mansoni serine/threonine protein kinase 0.0153 0.0061 0.0179
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0356 0.0378 0.0676
Schistosoma mansoni serine/threonine protein kinase 0.0121 0.0011 0.0022
Giardia lamblia Kinase, CMGC CK2 0.0172 0.0091 0.0949
Echinococcus multilocularis protein kinase c iota type 0.0473 0.0561 0.1032
Onchocerca volvulus Tyrosine kinase homolog 0.0799 0.1072 0.3241
Schistosoma mansoni protein kinase 0.0179 0.0101 0.0304
Plasmodium vivax unspecified product 0.0172 0.0091 0.0986
Echinococcus granulosus dual specificity protein kinase clk2 0.0701 0.0919 0.2813
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0661 0.0856 0.1601
Echinococcus multilocularis ephrin type A receptor 4 A 0.0163 0.0076 0.0094
Schistosoma mansoni protein kinase 0.0247 0.0207 0.0638
Plasmodium falciparum casein kinase 2, alpha subunit 0.0172 0.0091 0.0986
Loa Loa (eye worm) TK/FER protein kinase 0.0175 0.0095 0.0084
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.1073 0.15 0.4649
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0366 0.0394 0.0384
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0139 0.0039 0.0036
Echinococcus granulosus expressed protein 0.0153 0.0061 0.0105
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0187 0.0115 0.0168
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Echinococcus multilocularis PAK box P21 Rho binding 0.0179 0.0101 0.0141
Loa Loa (eye worm) AGC/PKA protein kinase 0.0661 0.0856 0.0846
Entamoeba histolytica serine/threonine protein kinase, putative 0.0117 0.0004 0.0014
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0686 0.0895 0.2738
Trypanosoma brucei polo-like protein kinase 0.0364 0.039 0.4243
Loa Loa (eye worm) TK/FER protein kinase 0.0175 0.0095 0.0084
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0222 0.0169 0.0274
Loa Loa (eye worm) TK/EGFR protein kinase 0.0786 0.1051 0.1041
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0661 0.0856 0.9307
Trichomonas vaginalis CAMK family protein kinase 0.0183 0.0108 0.117
Brugia malayi Immunoglobulin I-set domain containing protein 0.0455 0.0533 0.0523
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.025 0.0213 0.0811
Trichomonas vaginalis AGC family protein kinase 0.0459 0.054 0.5867
Brugia malayi cell division control protein 2 homolog 0.0702 0.0919 0.091
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0236 0.019 0.2068
Trichomonas vaginalis CAMK family protein kinase 0.0202 0.0137 0.1489
Leishmania major casein kinase II, putative 0.0172 0.0091 0.0986
Trypanosoma cruzi cdc2-related kinase 1 0.0702 0.0919 1
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0256 0.0222 0.0211
Trichomonas vaginalis CMGC family protein kinase 0.0172 0.0091 0.0986
Brugia malayi Immunoglobulin I-set domain containing protein 0.0204 0.014 0.0129
Trichomonas vaginalis AGC family protein kinase 0.0459 0.054 0.5867
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0356 0.0378 0.0676
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Echinococcus granulosus NCK adaptor protein 0.0136 0.0034 0.0021
Trichomonas vaginalis CMGC family protein kinase 0.0665 0.0862 0.937
Echinococcus multilocularis growth factor receptor bound protein 2 0.0136 0.0034 0.0013
Trichomonas vaginalis AGC family protein kinase 0.012 0.0008 0.0092
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Brugia malayi Protein kinase domain containing protein 0.0175 0.0095 0.0084
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0236 0.019 0.0314
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0661 0.0856 0.1601
Trichomonas vaginalis CAMK family protein kinase 0.0117 0.0004 0.0041
Trichomonas vaginalis cAMP-dependent protein kinase catalytic subunit, putative 0.012 0.0008 0.0092
Schistosoma mansoni tyrosine kinase 0.0227 0.0176 0.0541
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.022 0.0166 0.0436
Trichomonas vaginalis CAMK family protein kinase 0.0183 0.0108 0.117
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0294 0.0282 0.0271
Echinococcus multilocularis rho associated protein kinase 0.2157 0.3196 0.6124
Entamoeba histolytica protein kinase, putative 0.028 0.026 0.0988
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0036 0.0391
Echinococcus granulosus tyrosine protein kinase Src64B 0.0356 0.0378 0.1105
Entamoeba histolytica protein kinase domain containing protein 0.1794 0.2628 1
Loa Loa (eye worm) hypothetical protein 0.0343 0.0357 0.0347
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0503 0.0608 0.0598
Schistosoma mansoni protein kinase 0.102 0.1417 0.4427
Trichomonas vaginalis STE family protein kinase 0.0247 0.0207 0.2256
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0661 0.0856 0.9307
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0701 0.0919 0.9993
Schistosoma mansoni serine/threonine protein kinase 0.0121 0.0011 0.0022
Entamoeba histolytica protein kinase domain containing protein 0.0553 0.0686 0.2612
Entamoeba histolytica p21-activated kinase 0.0221 0.0166 0.0633
Schistosoma mansoni cell adhesion molecule 0.0231 0.0182 0.0559
Trichomonas vaginalis AGC family protein kinase 0.012 0.0008 0.0092
Entamoeba histolytica protein kinase, putative 0.0302 0.0294 0.112
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Schistosoma mansoni serine/threonine protein kinase 0.0503 0.0608 0.1894
Schistosoma mansoni serine/threonine protein kinase 0.0138 0.0037 0.0103
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0035 0.0384
Loa Loa (eye worm) hypothetical protein 0.0204 0.014 0.0129
Entamoeba histolytica protein kinase domain containing protein 0.028 0.026 0.0988
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0414 0.0469 0.0854
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0161 0.0074 0.0219
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0211 0.0151 0.0239
Trichomonas vaginalis AGC family protein kinase 0.012 0.0008 0.0092
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0661 0.0856 0.9307
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.1794 0.2628 0.262
Schistosoma mansoni serine/threonine protein kinase 0.0487 0.0584 0.1818
Schistosoma mansoni protein kinase 0.0169 0.0086 0.0258
Trichomonas vaginalis CAMK family protein kinase 0.0183 0.0108 0.117
Trichomonas vaginalis CAMK family protein kinase 0.0183 0.0108 0.117
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0161 0.0074 0.0219
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Echinococcus multilocularis cyclin dependent kinase 1 0.0702 0.0919 0.1724
Brugia malayi Variant SH3 domain containing protein 0.0136 0.0034 0.0024
Echinococcus granulosus tyrosine protein kinase Srms 0.0633 0.0812 0.2477
Brugia malayi Protein kinase domain containing protein 0.035 0.0369 0.0359
Echinococcus multilocularis cyclin dependent kinase 1 0.0702 0.0919 0.1724
Schistosoma mansoni serine/threonine protein kinase 0.0154 0.0062 0.0182
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0501 0.0605 0.1823
Loa Loa (eye worm) hypothetical protein 0.0193 0.0123 0.0113
Echinococcus multilocularis titin 0.0148 0.0053 0.0049
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0153 0.0061 0.005
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0256 0.0222 0.2413
Brugia malayi Protein kinase domain containing protein 0.0564 0.0704 0.0694
Echinococcus multilocularis dual specificity 0.0553 0.0686 0.1273
Loa Loa (eye worm) hypothetical protein 0.0387 0.0427 0.0417
Schistosoma mansoni tyrosine kinase 0.0227 0.0176 0.0541
Echinococcus multilocularis calcium dependent protein kinase 0.0159 0.0071 0.0083
Brugia malayi SH2 domain containing protein 0.0175 0.0095 0.0084
Leishmania major protein kinase, putative,serine/threonine-protein kinase Nek1, putative 0.0117 0.0004 0.0041
Loa Loa (eye worm) AGC/PKN protein kinase 0.0834 0.1126 0.1116
Echinococcus granulosus twitchin 0.0331 0.0339 0.0982
Echinococcus granulosus protein kinase c epsilon type 0.0381 0.0418 0.1231
Trypanosoma cruzi polo-like protein kinase, putative 0.0364 0.039 0.4243
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0553 0.0686 0.7465
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0217 0.016 0.0256
Onchocerca volvulus 0.0438 0.0506 0.1441
Echinococcus granulosus glycogen synthase kinase 3 beta 0.067 0.087 0.2659
Plasmodium falciparum NIMA related kinase 1 0.0213 0.0154 0.1676
Onchocerca volvulus 0.2157 0.3196 1
Leishmania major protein kinase, putative 0.025 0.0213 0.2317
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0256 0.0222 0.2413
Echinococcus granulosus tyrosine protein kinase Lyn 0.0452 0.0529 0.1582
Echinococcus multilocularis mitogen activated protein kinase 14 0.0366 0.0394 0.0709
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0366 0.0394 0.4288
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0784 0.1048 0.3222
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.067 0.087 0.946
Trypanosoma cruzi Serine/threonine-protein kinase NEK16, putative 0.0117 0.0004 0.0041
Plasmodium vivax calcium-dependent protein kinase, putative 0.0256 0.0222 0.2413
Echinococcus multilocularis rac serine:threonine kinase 0.0253 0.0218 0.0367
Echinococcus granulosus protein kinase c iota type 0.0473 0.0561 0.1685
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0701 0.0919 0.9993
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0183 0.0108 0.117
Onchocerca volvulus 0.206 0.3044 0.9519
Schistosoma mansoni serine/threonine protein kinase 0.0591 0.0746 0.2325
Brugia malayi Protein kinase domain containing protein 0.0676 0.0879 0.0869
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0193 0.0123 0.0375
Trichomonas vaginalis CMGC family protein kinase 0.0172 0.0091 0.0986
Trichomonas vaginalis AGC family protein kinase 0.012 0.0008 0.0092
Trypanosoma brucei rac serine-threonine kinase, putative 0.0459 0.054 0.5867
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0433 0.0499 0.1488
Echinococcus multilocularis roundabout 2 0.0272 0.0246 0.0423
Trichomonas vaginalis CMGC family protein kinase 0.0172 0.0091 0.0986
Echinococcus multilocularis dual specificity 0.0216 0.0159 0.0254
Trichomonas vaginalis CK1 family protein kinase 0.0294 0.0282 0.3065
Echinococcus granulosus cGMP dependent protein kinase 0.0211 0.0151 0.0391
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0216 0.0159 0.0149
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0661 0.0856 0.9307
Trichomonas vaginalis CAMK family protein kinase 0.0433 0.0499 0.5428
Trichomonas vaginalis CMGC family protein kinase 0.0665 0.0862 0.937
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0661 0.0856 0.9307
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0256 0.0222 0.2413
Plasmodium falciparum NIMA related kinase 4 0.0117 0.0004 0.0041
Trichomonas vaginalis AGC family protein kinase 0.028 0.026 0.2823
Schistosoma mansoni protein kinase C mu 0.0517 0.063 0.1961
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0244 0.0203 0.0193
Schistosoma mansoni tyrosine kinase 0.0614 0.0782 0.2437
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0172 0.0091 0.0986
Leishmania major casein kinase, putative 0.0294 0.0282 0.3065
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Echinococcus multilocularis protein tyrosine kinase 0.0347 0.0364 0.0651
Entamoeba histolytica protein kinase, putative 0.0257 0.0224 0.0853
Trichomonas vaginalis CMGC family protein kinase 0.0172 0.0091 0.0986
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0236 0.019 0.2068
Entamoeba histolytica protein kinase, putative 0.0153 0.0061 0.0231
Entamoeba histolytica protein kinase, putative 0.0151 0.0058 0.022
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0036 0.0391
Loa Loa (eye worm) hypothetical protein 0.0387 0.0427 0.0417
Trypanosoma brucei Mitogen-activated protein kinase 10, putative 0.0137 0.0035 0.0384
Loa Loa (eye worm) hypothetical protein 0.0297 0.0285 0.0275
Schistosoma mansoni serine/threonine protein kinase 0.0616 0.0785 0.2447
Trypanosoma brucei aurora B kinase 0.028 0.026 0.2823
Trichomonas vaginalis CMGC family protein kinase 0.0154 0.0062 0.0673
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0187 0.0115 0.1247
Schistosoma mansoni serine/threonine protein kinase 0.0701 0.0919 0.2867
Brugia malayi Tyrosine-protein kinase abl-1 0.0316 0.0316 0.0306
Trichomonas vaginalis CMGC family protein kinase 0.0216 0.0159 0.173
Trichomonas vaginalis CAMK family protein kinase 0.0256 0.0222 0.2413
Trichomonas vaginalis CMGC family protein kinase 0.0702 0.0919 1
Echinococcus granulosus Immunoglobulin 0.0193 0.0123 0.0302
Toxoplasma gondii AGC kinase 0.0661 0.0856 0.9307
Brugia malayi Immunoglobulin I-set domain containing protein 0.0978 0.1352 0.1343
Schistosoma mansoni serine/threonine protein kinase 0.0244 0.0203 0.0625
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0701 0.0919 0.0909
Plasmodium vivax serine/threonine protein kinase, putative 0.0153 0.0061 0.066
Entamoeba histolytica protein kinase domain containing protein 0.0187 0.0115 0.0436
Echinococcus granulosus homeodomain interacting protein kinase 3 0.1794 0.2628 0.8208
Echinococcus multilocularis neuroglian 0.0234 0.0188 0.0309
Loa Loa (eye worm) AUR protein kinase 0.028 0.026 0.0249
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0187 0.0115 0.0275
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Schistosoma mansoni serine/threonine kinase 0.0302 0.0294 0.0911
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Onchocerca volvulus 0.042 0.0478 0.1354
Echinococcus granulosus serine:threonine kinase SAD 1 0.0183 0.0108 0.0252
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0164 0.0077 0.0067
Loa Loa (eye worm) TK protein kinase 0.0237 0.0192 0.0182
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0356 0.0378 0.0676
Onchocerca volvulus 0.0665 0.0862 0.2573
Leishmania major protein kinase, putative 0.028 0.026 0.2823
Echinococcus granulosus neuropeptide s receptor 0.0558 0.0695 0.2107
Onchocerca volvulus 0.0297 0.0285 0.0739
Echinococcus multilocularis cyclin dependent kinase 7 0.0487 0.0584 0.1075
Echinococcus multilocularis death associated protein kinase 1 0.3438 0.5201 1
Loa Loa (eye worm) hypothetical protein 0.0142 0.0044 0.0033
Plasmodium falciparum calcium-dependent protein kinase 4 0.0256 0.0222 0.2413
Loa Loa (eye worm) hypothetical protein 0.042 0.0478 0.0468
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Entamoeba histolytica protein kinase, putative 0.0181 0.0104 0.0396
Loa Loa (eye worm) TK/FER protein kinase 0.0175 0.0095 0.0084
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0036 0.0391
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.067 0.087 0.2714
Trichomonas vaginalis STE family protein kinase 0.0247 0.0207 0.2256
Schistosoma mansoni serine/threonine protein kinase 0.0302 0.0294 0.0911
Echinococcus multilocularis dual specificity 0.0216 0.0159 0.0254
Entamoeba histolytica protein kinase, putative 0.0256 0.0222 0.0844
Trichomonas vaginalis CAMK family protein kinase 0.0183 0.0108 0.117
Schistosoma mansoni serine/threonine protein kinase 0.1875 0.2755 0.8619
Trichomonas vaginalis CMGC family protein kinase 0.0172 0.0091 0.0986
Brugia malayi map kinase activated protein kinase protein 2 0.0503 0.0608 0.0598
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0036 0.0391
Schistosoma mansoni serine/threonine protein kinase 0.0616 0.0785 0.2447
Brugia malayi p70 ribosomal S6 kinase beta 0.0441 0.0512 0.0502
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1605 0.2332 0.7275
Schistosoma mansoni tyrosine kinase 0.0159 0.007 0.0208
Plasmodium falciparum glycogen synthase kinase 3 0.067 0.087 0.946
Entamoeba histolytica casein kinase, putative 0.0294 0.0282 0.1072
Echinococcus multilocularis protein kinase c epsilon type 0.0381 0.0418 0.0754
Echinococcus granulosus dual specificity 0.0216 0.0159 0.0415
Echinococcus granulosus cyclin dependent kinase 9 0.0366 0.0394 0.1156
Giardia lamblia Aurora kinase 0.028 0.026 0.2794
Loa Loa (eye worm) hypothetical protein 0.023 0.0182 0.0171
Echinococcus granulosus serine:threonine protein kinase 3 0.0762 0.1014 0.3114
Schistosoma mansoni serine/threonine protein kinase 0.0285 0.0268 0.0827
Brugia malayi hypothetical protein 0.0387 0.0427 0.0417
Brugia malayi Protein kinase domain containing protein 0.0276 0.0254 0.0243
Echinococcus granulosus Glutaredoxin protein 5 0.0139 0.0039 0.0036
Echinococcus multilocularis CDC7 cell division cycle 7 0.0665 0.0862 0.1612
Trichomonas vaginalis CMGC family protein kinase 0.0137 0.0035 0.0384
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Loa Loa (eye worm) TK protein kinase 0.0455 0.0533 0.0523
Trypanosoma brucei NIMA-related protein kinase 0.0117 0.0004 0.0041
Giardia lamblia Kinase, NEK 0.0213 0.0154 0.1642
Leishmania major protein kinase A catalytic subunit 0.0661 0.0856 0.9307
Echinococcus granulosus casein kinase i 0.0294 0.0282 0.0802
Loa Loa (eye worm) TK/FER protein kinase 0.0175 0.0095 0.0084
Trichomonas vaginalis AGC family protein kinase 0.0459 0.054 0.5867
Echinococcus granulosus cyclin dependent kinase 9 0.0326 0.0331 0.0957
Echinococcus multilocularis 0.0605 0.0768 0.143
Echinococcus multilocularis tyrosine protein kinase HCK 0.0219 0.0165 0.0265
Echinococcus granulosus mitogen activated protein kinase 15 0.0137 0.0035 0.0024
Schistosoma mansoni protein kinase 0.028 0.026 0.0802
Entamoeba histolytica protein kinase, putative 0.0196 0.0128 0.0488
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0154 0.0062 0.0673
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0701 0.0919 0.9993
Loa Loa (eye worm) haspin protein kinase 0.0137 0.0035 0.0025
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0222 0.0169 0.0448
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.025 0.0213 0.2317
Trichomonas vaginalis STE family protein kinase 0.0179 0.0101 0.1095
Echinococcus multilocularis tyrosine protein kinase Abl 0.0316 0.0316 0.0557
Entamoeba histolytica protein kinase, putative 0.0553 0.0686 0.2612
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0484 0.0578 0.1739
Echinococcus multilocularis expressed protein 0.0153 0.0061 0.0064
Giardia lamblia Kinase, PLK 0.0364 0.039 0.4219
Brugia malayi Hr1 repeat family protein 0.0834 0.1126 0.1116
Brugia malayi hypothetical protein 0.0501 0.0605 0.0595
Loa Loa (eye worm) CAMK protein kinase 0.0148 0.0053 0.0042
Entamoeba histolytica protein kinase, putative 0.0203 0.0139 0.0528
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Giardia lamblia Kinase, AGC PKA 0.0236 0.019 0.2035
Trichomonas vaginalis STE family protein kinase 0.0213 0.0154 0.1676
Echinococcus granulosus dual specificity 0.0553 0.0686 0.2079
Trichomonas vaginalis protein kinase atmrk1, putative 0.0137 0.0035 0.0384
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0364 0.039 0.0701
Entamoeba histolytica protein kinase, putative 0.0216 0.0159 0.0605
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0203 0.0139 0.0215
Loa Loa (eye worm) hypothetical protein 0.0661 0.0856 0.0846
Schistosoma mansoni serine/threonine protein kinase 0.0256 0.0222 0.0683
Brugia malayi Kinase associated domain 1 family protein 0.0201 0.0136 0.0126
Trichomonas vaginalis AGC family protein kinase 0.012 0.0008 0.0092
Brugia malayi Protein kinase domain containing protein 0.1033 0.1438 0.1429
Echinococcus granulosus activated cdc42 kinase 1 0.0259 0.0226 0.0627
Brugia malayi Protein kinase domain containing protein 0.0137 0.0035 0.0025
Trichomonas vaginalis CMGC family protein kinase 0.0216 0.0159 0.173
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0356 0.0378 0.1105
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0408 0.046 0.0836
Brugia malayi Casein kinase II, alpha chain 0.0172 0.0091 0.008
Schistosoma mansoni tyrosine kinase 0.0414 0.0469 0.1459
Entamoeba histolytica protein kinase , putative 0.028 0.026 0.0988
Schistosoma mansoni serine/threonine-protein kinase 0.0253 0.0218 0.067
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0137 0.0036 0.0391
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0356 0.0378 0.0676
Trichomonas vaginalis CAMK family protein kinase 0.0433 0.0499 0.5428
Trichomonas vaginalis AGC family protein kinase 0.0459 0.054 0.5867
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0035 0.0384
Plasmodium falciparum calcium-dependent protein kinase 1 0.0256 0.0222 0.2413
Trichomonas vaginalis AGC family protein kinase 0.012 0.0008 0.0092
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0247 0.0207 0.0197
Trypanosoma cruzi NIMA-related kinase, putative 0.0117 0.0004 0.0041
Loa Loa (eye worm) hypothetical protein 0.0194 0.0124 0.0114
Toxoplasma gondii AGC kinase 0.0661 0.0856 0.9307
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0159 0.0069 0.0059
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.067 0.087 0.1628
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0439 0.0509 0.0499
Echinococcus granulosus serine:threonine protein kinase N2 0.0531 0.0653 0.1973
Echinococcus multilocularis aurora kinase A 0.028 0.026 0.0449
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0281 0.0261 0.2837
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0036 0.0391
Entamoeba histolytica protein kinase, putative 0.0219 0.0165 0.0627
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0139 0.0039 0.0022
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0136 0.0034 0.0024
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0227 0.0176 0.0166
Schistosoma mansoni serine/threonine protein kinase 0.0225 0.0173 0.053
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0213 0.0154 0.1676
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0139 0.0039 0.0022
Trypanosoma cruzi p21-activated kinase 3, putative 0.0121 0.0011 0.0116
Echinococcus granulosus activated cdc42 kinase 1 0.0259 0.0226 0.0627
Schistosoma mansoni protein kinase 0.0276 0.0254 0.0783
Schistosoma mansoni hypothetical protein 0.0387 0.0427 0.1327
Schistosoma mansoni serine/threonine protein kinase 0.0487 0.0583 0.1813
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0389 0.043 0.042
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Schistosoma mansoni serine/threonine protein kinase 0.0364 0.039 0.121
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.028 0.026 0.0449
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0156 0.0066 0.012
Trichomonas vaginalis STE family protein kinase 0.0203 0.0139 0.151
Echinococcus multilocularis neuropeptide receptor A26 0.0558 0.0695 0.129
Trichomonas vaginalis AGC family protein kinase 0.0151 0.0058 0.0629
Entamoeba histolytica PH domain containing protein kinase, putative 0.0253 0.0218 0.0828
Brugia malayi Variant SH3 domain containing protein 0.0136 0.0034 0.0024
Echinococcus granulosus serine:threonine protein kinase NLK 0.0137 0.0035 0.0024
Schistosoma mansoni kinase 0.0326 0.0331 0.1025
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Echinococcus multilocularis serine:threonine protein kinase N2 0.0302 0.0294 0.0516
Entamoeba histolytica protein kinase, putative 0.0459 0.054 0.2053
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0503 0.0608 0.1833
Schistosoma mansoni serine/threonine protein kinase 0.0298 0.0288 0.0889
Schistosoma mansoni atypical protein kinase C 0.048 0.0572 0.178
Trichomonas vaginalis AGC family protein kinase 0.0343 0.0358 0.3892
Onchocerca volvulus 0.0175 0.0095 0.0133
Giardia lamblia Kinase, CAMK CAMKL 0.0223 0.017 0.182
Plasmodium falciparum protein serine/threonine kinase-1 0.0701 0.0919 0.9993
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0389 0.043 0.042
Echinococcus granulosus cGMP dependent protein kinase 1 0.0211 0.0151 0.0391
Trichomonas vaginalis STE family protein kinase 0.0203 0.0139 0.151
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0389 0.043 0.127
Trichomonas vaginalis AGC family protein kinase 0.0137 0.0036 0.0391
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0256 0.0222 0.0613
Echinococcus multilocularis casein kinase I alpha 0.0294 0.0282 0.0491
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0501 0.0605 0.0595
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0137 0.0036 0.0391
Echinococcus granulosus protein kinase C gamma type 0.0348 0.0366 0.1069
Trypanosoma cruzi Mitogen-activated protein kinase 10, putative 0.0137 0.0035 0.0384
Giardia lamblia Kinase, STE STE20 0.0247 0.0207 0.2225
Trypanosoma brucei protein kinase, putative 0.0187 0.0115 0.1247
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0153 0.0061 0.066
Brugia malayi serine/threonine-protein kinase PAK 7 0.0866 0.1176 0.1167
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.1144 0.1611 0.5
Echinococcus granulosus cyclin dependent kinase 5 0.0702 0.0919 0.2815
Schistosoma mansoni nck2/grb4 0.0136 0.0034 0.0095
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Trichomonas vaginalis CAMK family protein kinase 0.0137 0.0035 0.0384
Plasmodium falciparum serine/threonine protein kinase, putative 0.028 0.026 0.2823

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 7.9433 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Influenza NS1 Protein Function. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Antagonists of the Neuropeptide S Receptor: cAMP Signal Transduction. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 13.1154 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) 50.1187 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 56.2341 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease. (Class of assay: confirmatory) [Related pubchem assays: 997 ] ChEMBL. No reference
Potency (functional) = 56.2341 um PUBCHEM_BIOASSAY: qHTS Assay for Activators of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease. (Class of assay: confirmatory) [Related pubchem assays: 1467, 2100, 2112, 1473, 1466 ] ChEMBL. No reference
Potency (functional) = 89.1251 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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