Detailed information for compound 1382286

Basic information

Technical information
  • TDR Targets ID: 1382286
  • Name: 2-[(4-acetamidophenyl)sulfonylamino]-N-(4-eth oxyphenyl)propanamide
  • MW: 405.468 | Formula: C19H23N3O5S
  • H donors: 3 H acceptors: 4 LogP: 1.71 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOc1ccc(cc1)NC(=O)C(NS(=O)(=O)c1ccc(cc1)NC(=O)C)C
  • InChi: 1S/C19H23N3O5S/c1-4-27-17-9-5-16(6-10-17)21-19(24)13(2)22-28(25,26)18-11-7-15(8-12-18)20-14(3)23/h5-13,22H,4H2,1-3H3,(H,20,23)(H,21,24)
  • InChiKey: OYASULMYKCTMLB-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 2-[(4-acetamidophenyl)sulfonylamino]-N-(4-ethoxyphenyl)propionamide
  • MLS001002555
  • SMR000369083

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis CAMK family protein kinase 0.015 0.0068 0.0636
Echinococcus granulosus nervana 2 0.0131 0.0039 0.0123
Brugia malayi Serine/threonine-protein kinase SULU 0.029 0.0272 0.0259
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0738 0.0927 0.9689
Schistosoma mansoni kinase 0.036 0.0375 0.1172
Schistosoma mansoni serine/threonine protein kinase 0.013 0.0039 0.0122
Entamoeba histolytica serine/threonine protein kinase, putative 0.015 0.0068 0.0228
Trichomonas vaginalis CMGC family protein kinase 0.0161 0.0084 0.0793
Echinococcus granulosus tyrosine protein kinase Fps85D 0.027 0.0243 0.0758
Echinococcus multilocularis roundabout 2 0.0163 0.0087 0.0229
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0144 0.0059 0.0608
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0144 0.0059 0.0608
Schistosoma mansoni serine/threonine protein kinase 0.2295 0.3201 1
Echinococcus multilocularis serine:threonine kinase SAD 1 0.015 0.0068 0.0179
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0694 0.0863 0.9023
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0589 0.0709 0.0696
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0122 0.0027 0.0086
Echinococcus granulosus defective proboscis extension response 0.0121 0.0026 0.0082
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0202 0.0144 0.013
Echinococcus multilocularis insulin receptor 0.0495 0.0572 0.1512
Brugia malayi Protein kinase c protein 2 0.0194 0.0132 0.0118
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0131 0.0039 0.0104
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0265 0.0235 0.0622
Giardia lamblia Kinase, STE STE20 0.0201 0.0142 0.1284
Echinococcus multilocularis ephrin type A receptor 4 A 0.0138 0.005 0.0133
Trichomonas vaginalis CAMK family protein kinase 0.015 0.0068 0.0636
Loa Loa (eye worm) hypothetical protein 0.0689 0.0855 0.0842
Brugia malayi hypothetical protein 0.0132 0.0042 0.0028
Trichomonas vaginalis AGC family protein kinase 0.0209 0.0154 0.1459
Echinococcus multilocularis aurora kinase A 0.0209 0.0154 0.0407
Echinococcus granulosus c src tyrosine kinase 0.0172 0.01 0.0312
Echinococcus granulosus casein kinase I delta 0.0251 0.0216 0.0673
Schistosoma mansoni serine/threonine protein kinase 0.0194 0.0132 0.0414
Trypanosoma cruzi casein kinase, putative 0.0251 0.0216 0.2246
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0194 0.0132 0.1376
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0738 0.0927 0.0914
Loa Loa (eye worm) AGC/PKA protein kinase 0.0694 0.0863 0.085
Trypanosoma cruzi casein kinase, putative 0.0251 0.0216 0.2246
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0161 0.0083 0.0221
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0161 0.0084 0.007
Echinococcus multilocularis 0.0606 0.0734 0.1939
Plasmodium falciparum casein kinase 1 0.0251 0.0216 0.2246
Echinococcus granulosus tyrosine kinase 0.0225 0.0178 0.0555
Onchocerca volvulus 0.0823 0.1051 0.3245
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0744 0.0935 0.0922
Schistosoma mansoni serine/threonine protein kinase 0.0341 0.0347 0.1083
Brugia malayi hypothetical protein 0.0336 0.0339 0.0326
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0265 0.0235 0.0622
Trichomonas vaginalis CMGC family protein kinase 0.0161 0.0084 0.0793
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0252 0.0216 0.0203
Echinococcus granulosus neuroglian 0.0141 0.0055 0.0172
Schistosoma mansoni serine/threonine protein kinase 0.0267 0.0239 0.0748
Echinococcus granulosus cyclin dependent kinase 9 0.0333 0.0335 0.1045
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0738 0.0927 0.9689
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0215 0.0162 0.0149
Echinococcus granulosus casein kinase ii subunit alpha 0.0161 0.0084 0.0263
Entamoeba histolytica protein kinase , putative 0.0209 0.0154 0.0523
Trichomonas vaginalis CAMK family protein kinase 0.0341 0.0347 0.3291
Plasmodium falciparum serine/threonine protein kinase, putative 0.0209 0.0154 0.1604
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0141 0.0055 0.0564
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0194 0.0132 0.035
Echinococcus granulosus casein kinase I alpha 0.0251 0.0216 0.0673
Leishmania major casein kinase, putative 0.0251 0.0216 0.2246
Trichomonas vaginalis CAMK family protein kinase 0.0353 0.0364 0.3454
Echinococcus granulosus Vam6:Vps39 protein 0.0336 0.0339 0.106
Entamoeba histolytica p21-activated kinase 0.0194 0.0132 0.0447
Trichomonas vaginalis AGC family protein kinase 0.0141 0.0055 0.052
Trichomonas vaginalis CMGC family protein kinase 0.0144 0.0059 0.0553
Echinococcus granulosus epidermal growth factor receptor 0.0667 0.0823 0.2571
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0472 0.0538 0.168
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0252 0.0216 0.0676
Echinococcus granulosus tyrosine protein kinase Blk 0.0225 0.0178 0.0555
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Trichomonas vaginalis CMGC family protein kinase 0.0161 0.0084 0.0793
Giardia lamblia Kinase, NEK 0.0199 0.014 0.1262
Trichomonas vaginalis AGC family protein kinase 0.0209 0.0154 0.1459
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0577 0.0692 0.1829
Loa Loa (eye worm) TK/FER protein kinase 0.0132 0.0042 0.0028
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0208 0.0153 0.0405
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0221 0.0171 0.0535
Echinococcus granulosus homeodomain interacting protein kinase 3 0.2109 0.293 0.9152
Echinococcus granulosus mitogen activated protein kinase 14 0.0223 0.0175 0.0547
Trichomonas vaginalis AGC family protein kinase 0.0141 0.0055 0.052
Leishmania major serine/threonine kinase-like protein, putative 0.0133 0.0043 0.0438
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0694 0.0863 0.2281
Schistosoma mansoni serine/threonine protein kinase 0.015 0.0068 0.0211
Echinococcus granulosus dual specificity 0.0202 0.0144 0.045
Brugia malayi protein-tyrosine kinase 0.0225 0.0178 0.0164
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Entamoeba histolytica protein kinase, putative 0.018 0.0111 0.0377
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0265 0.0235 0.0622
Loa Loa (eye worm) hypothetical protein 0.0128 0.0035 0.0021
Echinococcus multilocularis casein kinase i 0.0251 0.0216 0.057
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0251 0.0216 0.0202
Loa Loa (eye worm) haspin protein kinase 0.0133 0.0043 0.0029
Trichomonas vaginalis AGC family protein kinase 0.0126 0.0032 0.03
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0333 0.0335 0.0321
Schistosoma mansoni serine/threonine protein kinase 0.0255 0.0222 0.0692
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0012 0.0108
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0194 0.0132 0.1376
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0353 0.0364 0.1136
Trichomonas vaginalis AGC family protein kinase 0.04 0.0433 0.4109
Trypanosoma brucei rac serine-threonine kinase, putative 0.04 0.0433 0.4517
Echinococcus granulosus cGMP dependent protein kinase 0.0198 0.0137 0.0429
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Loa Loa (eye worm) hypothetical protein 0.0152 0.007 0.0056
Giardia lamblia Kinase, AGC AKT 0.0179 0.011 0.0981
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Schistosoma mansoni ephrin receptor 0.0138 0.005 0.0157
Entamoeba histolytica protein kinase, putative 0.0143 0.0058 0.0195
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0694 0.0863 0.9023
Echinococcus granulosus NDR protein kinase 0.0255 0.0222 0.0692
Loa Loa (eye worm) hypothetical protein 0.0121 0.0026 0.0012
Plasmodium falciparum casein kinase 2, alpha subunit 0.0161 0.0084 0.0872
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0694 0.0863 0.9023
Schistosoma mansoni serine/threonine protein kinase 0.0253 0.0218 0.0681
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0144 0.0059 0.0608
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.018 0.0111 0.0294
Echinococcus granulosus serine:threonine protein kinase 3 0.0569 0.068 0.2123
Trichomonas vaginalis AGC family protein kinase 0.04 0.0433 0.4109
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Schistosoma mansoni tyrosine kinase 0.0265 0.0235 0.0735
Toxoplasma gondii casein kinase I 0.0251 0.0216 0.2246
Schistosoma mansoni serine/threonine protein kinase 0.0317 0.0312 0.0974
Schistosoma mansoni tyrosine kinase 0.028 0.0257 0.0804
Schistosoma mansoni serine/threonine protein kinase 0.0143 0.0058 0.0181
Brugia malayi Protein kinase domain containing protein 0.0132 0.0042 0.0028
Echinococcus multilocularis tyrosine protein kinase Srms 0.0225 0.0178 0.047
Brugia malayi Protein kinase domain containing protein 0.0689 0.0855 0.0842
Loa Loa (eye worm) AGC/PKA protein kinase 0.0694 0.0863 0.085
Trichomonas vaginalis CAMK family protein kinase 0.015 0.0068 0.0636
Brugia malayi cyclin-dependent kinase 9 0.0333 0.0335 0.0321
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0341 0.0347 0.0333
Brugia malayi Protein kinase domain containing protein 0.0143 0.0058 0.0044
Trichomonas vaginalis AGC family protein kinase 0.0133 0.0043 0.0398
Echinococcus multilocularis fibroblast growth factor receptor 4 0.028 0.0257 0.068
Echinococcus multilocularis calcium dependent protein kinase 0.0104 0.0001 0.0001
Trichomonas vaginalis CAMK family protein kinase 0.015 0.0068 0.0636
Schistosoma mansoni rap gtpase-activating protein 0.0336 0.0339 0.106
Plasmodium falciparum serine/threonine protein kinase KIN 0.015 0.0068 0.0699
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0738 0.0927 0.2895
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0209 0.0154 0.0482
Trichomonas vaginalis CMGC family protein kinase 0.0823 0.1051 1
Schistosoma mansoni protein kinase C mu 0.0432 0.048 0.15
Entamoeba histolytica PH domain containing protein kinase, putative 0.0708 0.0883 0.3013
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0265 0.0235 0.0622
Schistosoma mansoni serine/threonine protein kinase 0.0744 0.0935 0.2921
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0432 0.048 0.0467
Loa Loa (eye worm) hypothetical protein 0.0285 0.0265 0.0252
Entamoeba histolytica hypothetical protein 0.0401 0.0435 0.1482
Echinococcus granulosus tyrosine protein kinase HCK 0.0163 0.0087 0.0273
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0694 0.0863 0.085
Trichomonas vaginalis CAMK family protein kinase 0.0341 0.0347 0.3291
Loa Loa (eye worm) AUR protein kinase 0.0209 0.0154 0.014
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.6949 1 1
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Brugia malayi Protein kinase domain containing protein 0.0133 0.0043 0.0029
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0502 0.0582 0.1817
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0193 0.0131 0.1357
Brugia malayi Protein kinase domain containing protein 0.0141 0.0055 0.0041
Schistosoma mansoni vav2 0.0136 0.0048 0.0149
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0198 0.0137 0.1428
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0012 0.0108
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0901 0.1164 0.3638
Brugia malayi Protein kinase domain containing protein 0.0495 0.0572 0.0559
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Schistosoma mansoni serine/threonine protein kinase 0.015 0.0068 0.0211
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Echinococcus granulosus cGMP dependent protein kinase 1 0.0198 0.0137 0.0429
Plasmodium vivax serine/threonine-protein kinase Nek1, putative 0.0109 0.0008 0.0075
Schistosoma mansoni serine/threonine protein kinase 0.0694 0.0863 0.2696
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0251 0.0216 0.0202
Giardia lamblia Kinase, CAMK CAMKL 0.0192 0.013 0.1166
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0202 0.0144 0.1499
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.018 0.0111 0.0348
Brugia malayi Fibronectin type III domain containing protein 0.0128 0.0035 0.0021
Entamoeba histolytica protein kinase, putative 0.04 0.0433 0.1474
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0143 0.0058 0.0597
Plasmodium falciparum calcium-dependent protein kinase 2 0.0194 0.0132 0.1376
Echinococcus multilocularis CDC7 cell division cycle 7 0.0823 0.1051 0.2779
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0738 0.0927 0.9689
Echinococcus multilocularis protein kinase shaggy 0.0758 0.0957 0.2528
Entamoeba histolytica protein kinase domain containing protein 0.0758 0.0957 0.3263
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0116 0.0019 0.0005
Leishmania major protein kinase, putative 0.0209 0.0154 0.1604
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.029 0.0272 0.072
Trypanosoma cruzi SNF1-related protein kinases, putative 0.015 0.0068 0.0699
Echinococcus granulosus serine:threonine protein kinase 0.0133 0.0043 0.0135
Echinococcus granulosus cyclin dependent kinase 19 0.0371 0.039 0.1218
Trichomonas vaginalis CMGC family protein kinase 0.0758 0.0957 0.9097
Schistosoma mansoni hypothetical protein 0.0336 0.0339 0.106
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0386 0.0412 0.0399
Trichomonas vaginalis CMGC family protein kinase 0.0133 0.0043 0.0398
Entamoeba histolytica protein kinase domain containing protein 0.0161 0.0084 0.0285
Echinococcus granulosus mitogen activated protein kinase 11 0.0223 0.0175 0.0547
Trichomonas vaginalis AGC family protein kinase 0.04 0.0433 0.4109
Loa Loa (eye worm) hypothetical protein 0.0336 0.0339 0.0326
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0187 0.0121 0.1146
Echinococcus multilocularis cyclin dependent kinase 1 0.0738 0.0927 0.2449
Leishmania major protein kinase A catalytic subunit isoform 1 0.0694 0.0863 0.9023
Trichomonas vaginalis AGC family protein kinase 0.0277 0.0253 0.2401
Echinococcus granulosus cyclin dependent kinase 7 0.0504 0.0584 0.1826
Trichomonas vaginalis AGC family protein kinase 0.0184 0.0117 0.111
Trichomonas vaginalis AGC family protein kinase 0.04 0.0433 0.4109
Echinococcus multilocularis Cell division cycle 2 protein kinase 0.0133 0.0043 0.0113
Brugia malayi Protein kinase domain containing protein 0.0132 0.0042 0.0028
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0144 0.0059 0.0608
Plasmodium vivax protein kinase Crk2 0.0738 0.0927 0.9689
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.216 0.3005 0.794
Schistosoma mansoni microtubule-associated protein tau 0.0833 0.1066 0.333
Trypanosoma brucei casein kinase I, isoform 2 0.0251 0.0216 0.2246
Brugia malayi Protein kinase domain containing protein 0.0689 0.0855 0.0842
Echinococcus multilocularis dual specificity protein kinase clk2 0.0744 0.0935 0.2471
Schistosoma mansoni tyrosine kinase 0.0495 0.0572 0.1788
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Echinococcus granulosus insulin receptor 0.0495 0.0572 0.1788
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0453 0.0511 0.1351
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0336 0.0339 0.3541
Trichomonas vaginalis serine/threonine kinase, putative 0.0133 0.0043 0.0398
Schistosoma mansoni serine/threonine protein kinase 0.0202 0.0144 0.045
Brugia malayi serine/threonine-protein kinase PAK 7 0.0693 0.086 0.0848
Brugia malayi Protein kinase domain containing protein 0.216 0.3005 0.2995
Echinococcus multilocularis casein kinase I gamma 0.0281 0.0259 0.0683
Schistosoma mansoni serine/threonine protein kinase 0.0198 0.0137 0.0429
Plasmodium falciparum calcium-dependent protein kinase 5 0.0194 0.0132 0.1376
Trichomonas vaginalis CAMK family protein kinase 0.015 0.0068 0.0636
Trichomonas vaginalis CAMK family protein kinase 0.0341 0.0347 0.3291
Echinococcus granulosus ephrin type A receptor 4 A 0.0138 0.005 0.0157
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0744 0.0935 0.9774
Entamoeba histolytica protein kinase, putative 0.0375 0.0397 0.1353
Brugia malayi Stress-activated protein kinase jnk-1 0.0334 0.0337 0.0324
Echinococcus granulosus dual specificity 0.0202 0.0144 0.045
Brugia malayi Doublecortin family protein 0.0215 0.0162 0.0149
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0265 0.0235 0.0622
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0201 0.0142 0.1477
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.028 0.0257 0.068
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0221 0.0171 0.1784
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0199 0.014 0.1453
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0901 0.1164 0.1152
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.018 0.0111 0.0294
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0014 0.0044
Schistosoma mansoni tyrosine kinase 0.0105 0.0003 0.0009
Entamoeba histolytica protein kinase, putative 0.0758 0.0957 0.3263
Entamoeba histolytica casein kinase 1, putative 0.0251 0.0216 0.0733
Echinococcus multilocularis cyclin dependent kinase 9 0.0375 0.0397 0.1048
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0245 0.0206 0.0192
Trichomonas vaginalis AGC family protein kinase 0.0126 0.0032 0.03
Brugia malayi Protein kinase domain containing protein 0.032 0.0316 0.0303
Brugia malayi Temporarily assigned gene name protein 59 0.0136 0.0048 0.0034
Echinococcus multilocularis epidermal growth factor receptor 0.0667 0.0823 0.2175
Echinococcus granulosus protein kinase c epsilon type 0.0317 0.0312 0.0974
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0472 0.0538 0.1421
Echinococcus multilocularis mitogen activated protein kinase 3 0.0144 0.0059 0.0156
Schistosoma mansoni serine/threonine protein kinase 0.0131 0.004 0.0124
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0255 0.0222 0.0692
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0223 0.0175 0.1824
Trichomonas vaginalis protein kinase atmrk1, putative 0.0133 0.0043 0.0398
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0014 0.0044
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Brugia malayi Hr1 repeat family protein 0.0669 0.0826 0.0813
Loa Loa (eye worm) hypothetical protein 0.0402 0.0436 0.0422
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0252 0.0216 0.0572
Loa Loa (eye worm) hypothetical protein 0.0137 0.0048 0.0034
Trichomonas vaginalis CAMK family protein kinase 0.015 0.0068 0.0636
Schistosoma mansoni ste20-related kinase 0.0458 0.0518 0.1619
Schistosoma mansoni serine/threonine-protein kinase 0.0235 0.0192 0.0598
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0161 0.0083 0.0864
Brugia malayi Protein kinase domain containing protein 0.0823 0.1051 0.1039
Echinococcus multilocularis mitogen activated protein kinase 14 0.0223 0.0175 0.0463
Loa Loa (eye worm) hypothetical protein 0.0694 0.0863 0.085
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.0008 0.0068
Entamoeba histolytica protein kinase domain containing protein 0.0375 0.0397 0.1353
Giardia lamblia Kinase, CMGC CDK 0.0738 0.0927 0.8806
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Trypanosoma cruzi casein kinase, putative 0.0251 0.0216 0.2246
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0344 0.0351 0.1097
Leishmania major serine/threonine-protein kinase, putative 0.0109 0.0008 0.0075
Toxoplasma gondii NEK kinase 0.0109 0.0008 0.0075
Schistosoma mansoni serine/threonine protein kinase 0.0344 0.0351 0.1097
Echinococcus granulosus mitogen activated protein kinase 0.0144 0.0059 0.0184
Echinococcus granulosus protein kinase c iota type 0.0403 0.0438 0.1367
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0694 0.0863 0.9023
Onchocerca volvulus 0.0132 0.0042 0.0073
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0265 0.0235 0.0622
Brugia malayi probable protein kinase 0.0942 0.1224 0.1212
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0515 0.0601 0.0588
Echinococcus multilocularis cyclin dependent kinase 0.0738 0.0927 0.2449
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.216 0.3005 0.9382
Onchocerca volvulus 0.0161 0.0084 0.0204
Echinococcus multilocularis calcium activated potassium channel 0.0253 0.0218 0.0576
Trichomonas vaginalis AGC family protein kinase 0.04 0.0433 0.4109
Giardia lamblia Kinase, AGC PKA 0.0221 0.0171 0.1565
Schistosoma mansoni serine/threonine protein kinase 0.0823 0.1051 0.3285
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0229 0.0183 0.0483
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0694 0.0863 0.2281
Loa Loa (eye worm) TK/EPH protein kinase 0.0156 0.0077 0.0063
Schistosoma mansoni atypical protein kinase C 0.041 0.0447 0.1397
Echinococcus granulosus tyrosine protein kinase Fyn 0.0265 0.0235 0.0735
Trichomonas vaginalis STE family protein kinase 0.0157 0.0078 0.0734
Echinococcus granulosus casein kinase I alpha 0.0251 0.0216 0.0673
Schistosoma mansoni serine/threonine protein kinase 0.0255 0.0222 0.0692
Brugia malayi Protein kinase domain containing protein 0.0132 0.0042 0.0028
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0694 0.0863 0.2281
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Loa Loa (eye worm) hypothetical protein 0.0147 0.0063 0.0049
Echinococcus granulosus mitogen activated protein kinase 3 0.0144 0.0059 0.0184
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0157 0.0078 0.0206
Schistosoma mansoni tyrosine kinase 0.0447 0.0502 0.1568
Loa Loa (eye worm) protein kinase domain-containing protein 0.0281 0.0259 0.0245
Echinococcus granulosus Glutaredoxin protein 5 0.0131 0.0039 0.0123
Schistosoma mansoni serine/threonine protein kinase 0.0133 0.0043 0.0133
Schistosoma mansoni protein kinase 0.0901 0.1164 0.3638
Trichomonas vaginalis STE family protein kinase 0.018 0.0111 0.1052
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0255 0.0222 0.0586
Echinococcus multilocularis Glutaredoxin protein 5 0.0131 0.0039 0.0104
Brugia malayi Tyrosine-protein kinase abl-1 0.0256 0.0222 0.0208
Echinococcus granulosus casein kinase I gamma 0.0281 0.0259 0.0808
Trichomonas vaginalis STE family protein kinase 0.0201 0.0142 0.1344
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.015 0.0068 0.0054
Entamoeba histolytica protein kinase, putative 0.0152 0.0071 0.024
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0143 0.0058 0.0044
Entamoeba histolytica protein kinase, putative 0.0163 0.0087 0.0295
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0758 0.0957 0.0944
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.015 0.0068 0.0699
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0851 0.1092 0.3413
Echinococcus granulosus dual specificity protein kinase clk2 0.0744 0.0935 0.2921
Brugia malayi Protein kinase domain containing protein 0.0121 0.0025 0.0011
Echinococcus multilocularis dual specificity 0.0202 0.0144 0.0381
Trypanosoma cruzi casein kinase, putative 0.0251 0.0216 0.2246
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0255 0.0222 0.0586
Trichomonas vaginalis AGC family protein kinase 0.0133 0.0043 0.0398
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0426 0.0471 0.1245
Entamoeba histolytica cell division protein kinase 2, putative 0.0781 0.0989 0.3374
Loa Loa (eye worm) hypothetical protein 0.0147 0.0063 0.0049
Plasmodium falciparum NIMA related kinase 1 0.0199 0.014 0.1453
Giardia lamblia Kinase, CMGC DYRK 0.0202 0.0144 0.1304
Echinococcus multilocularis hypothetical protein 0.0162 0.0086 0.0227
Trypanosoma cruzi cdc2-related kinase 3 0.0738 0.0927 0.9689
Onchocerca volvulus 0.0282 0.026 0.0759
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Trichomonas vaginalis CAMK family protein kinase 0.0341 0.0347 0.3291
Schistosoma mansoni serine/threonine-protein kinase 0.0235 0.0192 0.0598
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Entamoeba histolytica PH domain containing protein kinase, putative 0.0235 0.0192 0.0651
Schistosoma mansoni tyrosine kinase 0.0416 0.0457 0.1426
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0131 0.0039 0.0123
Entamoeba histolytica casein kinase, putative 0.0251 0.0216 0.0733
Onchocerca volvulus 0.0147 0.0063 0.0138
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Brugia malayi STE20-like kinase MST 0.0569 0.068 0.0667
Brugia malayi Protein kinase domain containing protein 0.0229 0.0183 0.0169
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0126 0.0032 0.03
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0569 0.068 0.0667
Loa Loa (eye worm) CDC7 protein kinase 0.0823 0.1051 0.1039
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0694 0.0863 0.9023
Trypanosoma cruzi polo-like protein kinase, putative 0.0341 0.0347 0.3617
Trichomonas vaginalis AGC family protein kinase 0.0298 0.0284 0.2692
Schistosoma mansoni serine/threonine protein kinase 0.0738 0.0927 0.2895
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0758 0.0957 0.0944
Brugia malayi Protein kinase domain containing protein 0.0277 0.0253 0.0239
Brugia malayi Protein kinase domain containing protein 0.0276 0.0252 0.0239
Echinococcus multilocularis serine:threonine protein kinase 3 0.0569 0.068 0.1796
Schistosoma mansoni protein kinase 0.0161 0.0083 0.0261
Leishmania major protein kinase, putative 0.0744 0.0935 0.9774
Loa Loa (eye worm) CAMK/PIM protein kinase 0.216 0.3005 0.2995
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0012 0.0108
Trichomonas vaginalis AGC family protein kinase 0.0126 0.0032 0.03
Loa Loa (eye worm) hypothetical protein 0.0653 0.0803 0.079
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0295 0.028 0.0876
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0121 0.0026 0.0082
Echinococcus multilocularis serine:threonine protein kinase 0.0133 0.0043 0.0114
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0012 0.0108
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Trichomonas vaginalis CMGC family protein kinase 0.0133 0.0043 0.0398
Onchocerca volvulus 0.013 0.0038 0.0061
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0152 0.0071 0.024
Trichomonas vaginalis CMGC family protein kinase 0.0738 0.0927 0.8814
Brugia malayi Casein kinase II, alpha chain 0.0161 0.0084 0.007
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.028 0.0257 0.0804
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0538 0.0634 0.1981
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Echinococcus multilocularis tyrosine protein kinase HCK 0.0163 0.0087 0.0231
Echinococcus multilocularis mitogen activated protein kinase 11 0.0223 0.0175 0.0463
Echinococcus multilocularis mitogen activated protein kinase 0.0144 0.0059 0.0156
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0744 0.0935 0.9774
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0012 0.0108
Loa Loa (eye worm) AUR protein kinase 0.0209 0.0154 0.014
Echinococcus multilocularis serine threonine protein kinase 0.0298 0.0285 0.0752
Schistosoma mansoni tyrosine kinase 0.0172 0.01 0.0312
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0194 0.0132 0.0119
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Trypanosoma brucei SNF1-related protein kinases, putative 0.015 0.0068 0.0699
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0144 0.0059 0.0045
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0194 0.0132 0.0414
Trypanosoma cruzi p21-activated kinase 3, putative 0.0113 0.0014 0.0138
Loa Loa (eye worm) hypothetical protein 0.0282 0.026 0.0246
Echinococcus multilocularis cyclin dependent kinase 19 0.0371 0.039 0.1031
Echinococcus granulosus serine:threonine protein kinase TAO1 0.029 0.0272 0.0851
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.018 0.0111 0.0294
Schistosoma mansoni serine/threonine protein kinase 0.0281 0.0259 0.0808
Loa Loa (eye worm) TK/ALK protein kinase 0.032 0.0316 0.0303
Schistosoma mansoni serine/threonine protein kinase 0.0295 0.028 0.0876
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0251 0.0216 0.2246
Schistosoma mansoni titin 0.0116 0.0019 0.0059
Trichomonas vaginalis AGC family protein kinase 0.0277 0.0253 0.2401
Schistosoma mansoni serine/threonine protein kinase 0.0694 0.0863 0.2696
Trichomonas vaginalis CK1 family protein kinase 0.0251 0.0216 0.2043
Loa Loa (eye worm) hypothetical protein 0.0126 0.0032 0.0018
Brugia malayi hypothetical protein 0.029 0.0272 0.0259
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0143 0.0058 0.0597
Brugia malayi Protein kinase domain containing protein 0.0744 0.0935 0.0922
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0744 0.0935 0.9774
Trichomonas vaginalis AGC family protein kinase 0.0209 0.0154 0.1459
Trichomonas vaginalis CAMK family protein kinase 0.015 0.0068 0.0636
Entamoeba histolytica protein kinase, putative 0.0141 0.0055 0.0186
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0194 0.0132 0.1376
Trichomonas vaginalis AGC family protein kinase 0.0126 0.0032 0.03
Loa Loa (eye worm) hypothetical protein 0.0648 0.0795 0.0782
Loa Loa (eye worm) hypothetical protein 0.0147 0.0063 0.0049
Trichomonas vaginalis CAMK family protein kinase 0.015 0.0068 0.0636
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0141 0.0055 0.0173
Trichomonas vaginalis CMGC family protein kinase 0.0144 0.0059 0.0553
Schistosoma mansoni serine/threonine protein kinase 0.0538 0.0634 0.1981
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0353 0.0364 0.0961
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0758 0.0957 1
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0744 0.0935 0.9774
Echinococcus granulosus dual specificity 0.0202 0.0144 0.045
Entamoeba histolytica protein kinase, putative 0.013 0.0039 0.013
Trichomonas vaginalis G protein-coupled receptor kinase, putative 0.0133 0.0043 0.0398
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0277 0.0253 0.0239
Leishmania major mitogen-activated protein kinase, putative,map kinase-like protein 0.0133 0.0043 0.0438
Echinococcus granulosus tyrosine protein kinase Srms 0.0563 0.0671 0.2095
Loa Loa (eye worm) CMGC/CDK/CRK7 protein kinase 0.0133 0.0043 0.0029
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0122 0.0027 0.0086
Trichomonas vaginalis CMGC family protein kinase 0.0744 0.0935 0.8891
Loa Loa (eye worm) hypothetical protein 0.0207 0.0151 0.0137
Plasmodium falciparum glycogen synthase kinase 3 0.0758 0.0957 1
Entamoeba histolytica protein kinase, putative 0.0171 0.0098 0.0332
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Loa Loa (eye worm) hypothetical protein 0.0128 0.0035 0.0021
Loa Loa (eye worm) TK/FER protein kinase 0.0132 0.0042 0.0028
Trichomonas vaginalis AGC family protein kinase 0.0126 0.0032 0.03
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0012 0.0108
Brugia malayi Protein kinase domain containing protein 0.0529 0.0621 0.0608
Trichomonas vaginalis CAMK family protein kinase 0.0383 0.0409 0.3881
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0133 0.0044 0.003
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0504 0.0584 0.0571
Giardia lamblia Kinase, CMGC CK2 0.0161 0.0084 0.073
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0334 0.0337 0.0891
Trypanosoma brucei Serine/threonine-protein kinase NEK16, putative 0.0109 0.0008 0.0075
Loa Loa (eye worm) hypothetical protein 0.015 0.0068 0.0054
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0472 0.0538 0.0524
Trypanosoma cruzi cdc2-related kinase 3 0.0738 0.0927 0.9689
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0426 0.0471 0.1472
Brugia malayi RhoGAP domain containing protein 0.0122 0.0027 0.0013
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Schistosoma mansoni serine/threonine protein kinase 0.0229 0.0183 0.0571
Loa Loa (eye worm) TK/FER protein kinase 0.0132 0.0042 0.0028
Leishmania major protein kinase, putative 0.0194 0.0132 0.1376
Echinococcus granulosus expressed protein 0.0143 0.0058 0.0181
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0626 0.0763 0.2384
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0901 0.1164 0.3077
Loa Loa (eye worm) hypothetical protein 0.0356 0.0369 0.0355
Entamoeba histolytica protein kinase, putative 0.0255 0.0222 0.0754
Onchocerca volvulus 0.0132 0.0042 0.0073
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0122 0.0027 0.0013
Echinococcus granulosus dual specificity 0.0375 0.0397 0.124
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0626 0.0763 0.2017
Trichomonas vaginalis STE family protein kinase 0.0109 0.0008 0.0068
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0172 0.01 0.0312
Schistosoma mansoni serine/threonine protein kinase 0.0565 0.0674 0.2105
Schistosoma mansoni tyrosine kinase 0.0289 0.0271 0.0848
Echinococcus granulosus serine:threonine protein kinase 0.0133 0.0043 0.0135
Entamoeba histolytica protein kinase, putative 0.013 0.0039 0.013
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0403
Trichomonas vaginalis AGC family protein kinase 0.0126 0.0032 0.03
Trypanosoma cruzi Serine/threonine-protein kinase NEK16, putative 0.0109 0.0008 0.0075
Trichomonas vaginalis CMGC family protein kinase 0.0133 0.0043 0.0398
Loa Loa (eye worm) TK/FER protein kinase 0.0132 0.0042 0.0028
Trichomonas vaginalis CAMK family protein kinase 0.0341 0.0347 0.3291
Plasmodium vivax casein kinase 1, putative 0.0251 0.0216 0.2246
Echinococcus multilocularis tyrosine protein kinase Blk 0.0225 0.0178 0.047
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0758 0.0957 1
Entamoeba histolytica protein kinase 2, putative 0.0221 0.0171 0.0582
Schistosoma mansoni vesicular amine transporter 0.0121 0.0026 0.0082
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0375 0.0397 0.4146
Echinococcus multilocularis nervana 2 0.0131 0.0039 0.0104
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0694 0.0863 0.9023
Echinococcus multilocularis serine:threonine protein kinase 0.0133 0.0043 0.0114
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0202 0.0144 0.013
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0113 0.0014 0.0126
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0201 0.0142 0.0482
Loa Loa (eye worm) TK/EGFR protein kinase 0.0667 0.0823 0.081
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Trichomonas vaginalis CMGC family protein kinase 0.0161 0.0084 0.0793
Schistosoma mansoni serine/threonine protein kinase 0.1508 0.2052 0.6409
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0235 0.0192 0.1995
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0432 0.048 0.0467
Schistosoma mansoni serine/threonine protein kinase 0.0472 0.0538 0.168
Brugia malayi Protein kinase domain containing protein 0.0738 0.0927 0.0914
Onchocerca volvulus 0.0132 0.0042 0.0073
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.013 0.0039 0.0103
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0265 0.0235 0.0622
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0265 0.0235 0.0622
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Loa Loa (eye worm) TK/FER protein kinase 0.0132 0.0042 0.0028
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0336 0.0339 0.3541
Brugia malayi serine/threonine kinase 12 0.0209 0.0154 0.014
Loa Loa (eye worm) hypothetical protein 0.022 0.017 0.0156
Loa Loa (eye worm) TK/FER protein kinase 0.0132 0.0042 0.0028
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0689 0.0855 0.0842
Echinococcus granulosus serine threonine protein kinase nrc 0.0221 0.0171 0.0535
Loa Loa (eye worm) hypothetical protein 0.0199 0.014 0.0126
Entamoeba histolytica protein kinase, putative 0.0157 0.0078 0.0263
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0744 0.0935 0.9774
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0604 0.0731 0.2285
Loa Loa (eye worm) TK/FER protein kinase 0.027 0.0243 0.0229
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Brugia malayi Immunoglobulin I-set domain containing protein 0.0537 0.0633 0.062
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0198 0.0137 0.0363
Echinococcus granulosus Protein kinase C brain isozyme 0.0359 0.0373 0.1165
Entamoeba histolytica protein kinase, putative 0.0202 0.0144 0.0489
Schistosoma mansoni protein kinase 0.0161 0.0083 0.0261
Leishmania major protein kinase A catalytic subunit 0.0694 0.0863 0.9023
Echinococcus multilocularis casein kinase I alpha 0.0251 0.0216 0.057
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0194 0.0132 0.0119
Schistosoma mansoni tyrosine kinase 0.0447 0.0502 0.1568
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0371 0.039 0.0377
Giardia lamblia Kinase, NEK 0.0199 0.014 0.1262
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0341 0.0347 0.3617
Trichomonas vaginalis CMGC family protein kinase 0.0758 0.0957 0.9097
Toxoplasma gondii NEK kinase 0.0109 0.0008 0.0075
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0744 0.0935 0.9774
Plasmodium falciparum cGMP-dependent protein kinase 0.0198 0.0137 0.1428
Loa Loa (eye worm) hypothetical protein 0.0122 0.0027 0.0013
Schistosoma mansoni protein kinase 0.0161 0.0083 0.0261
Echinococcus granulosus serine/threonine protein kinase 0.0235 0.0192 0.0598
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0012 0.0108
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0537 0.0633 0.062
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0758 0.0957 0.2988
Plasmodium falciparum protein kinase 5 0.0738 0.0927 0.9689
Echinococcus multilocularis serine:threonine protein kinase N2 0.0669 0.0826 0.2184
Schistosoma mansoni protein kinase 0.0783 0.0993 0.3101
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0121 0.0026 0.0082
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0744 0.0935 0.9774
Echinococcus granulosus fibroblast growth factor receptor 4 0.028 0.0257 0.0804
Brugia malayi Serine/threonine-protein kinase Pim-3 0.216 0.3005 0.2995
Echinococcus granulosus tyrosine protein kinase Src64B 0.0265 0.0235 0.0735
Brugia malayi protein kinase C3,putative 0.0238 0.0197 0.0183
Entamoeba histolytica protein kinase, putative 0.0375 0.0397 0.1353
Brugia malayi Protein kinase domain containing protein 0.0132 0.0042 0.0028
Echinococcus multilocularis microtubule associated protein 2 0.0833 0.1066 0.2817
Plasmodium falciparum MO15-related protein kinase 0.0133 0.0043 0.0438
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0529 0.0621 0.0608
Echinococcus granulosus protein kinase shaggy 0.0758 0.0957 0.2988
Echinococcus multilocularis casein kinase I alpha 0.0251 0.0216 0.057
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0694 0.0863 0.2281
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Brugia malayi phosphoinositide-dependent protein kinase I 0.0141 0.0055 0.0041
Brugia malayi SH2 domain containing protein 0.0132 0.0042 0.0028
Trichomonas vaginalis CAMK family protein kinase 0.015 0.0068 0.0636
Entamoeba histolytica protein kinase, putative 0.0195 0.0134 0.0456
Brugia malayi Variant SH3 domain containing protein 0.0122 0.0027 0.0013
Echinococcus granulosus titin 0.0116 0.0019 0.0059
Schistosoma mansoni protein kinase 0.0209 0.0154 0.0482
Echinococcus multilocularis twitchin 0.011 0.0009 0.0025
Onchocerca volvulus 0.0823 0.1051 0.3245
Brugia malayi Protein kinase domain containing protein 0.0901 0.1164 0.1152
Trypanosoma brucei cdc2-related kinase 3 0.0738 0.0927 0.9689
Schistosoma mansoni serine/threonine protein kinase 0.0116 0.0019 0.0059
Echinococcus granulosus tyrosine protein kinase Fyn 0.0265 0.0235 0.0735
Echinococcus multilocularis dual specificity 0.0202 0.0144 0.0381
Brugia malayi P38 map kinase family protein 2 0.0223 0.0175 0.0161
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0375 0.0397 0.4146
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.0008 0.0068
Loa Loa (eye worm) hypothetical protein 0.0336 0.0339 0.0326
Schistosoma mansoni protein kinase 0.0157 0.0078 0.0244
Schistosoma mansoni protein kinase 0.0161 0.0084 0.0263
Loa Loa (eye worm) hypothetical protein 0.0336 0.0339 0.0326
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0133 0.0043 0.0438
Brugia malayi Protein kinase domain containing protein 0.0259 0.0227 0.0213
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0372 0.0392 0.0378
Echinococcus granulosus cyclin dependent kinase 0.0738 0.0927 0.2895
Echinococcus multilocularis 0.0183 0.0117 0.0308
Trichomonas vaginalis CK1 family protein kinase 0.0251 0.0216 0.2043
Toxoplasma gondii AGC kinase 0.0386 0.0412 0.4305
Onchocerca volvulus 0.0356 0.0369 0.1099
Echinococcus granulosus casein kinase I alpha 0.0251 0.0216 0.0673
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0012 0.0108
Onchocerca volvulus 0.0132 0.0042 0.0073
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0122 0.0027 0.0073
Schistosoma mansoni serine/threonine kinase 0.0255 0.0222 0.0692
Giardia lamblia Kinase, NEK 0.0199 0.014 0.1262
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0209 0.0154 0.0523
Loa Loa (eye worm) hypothetical protein 0.0282 0.026 0.0246
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0336 0.0339 0.106
Echinococcus granulosus calcium dependent protein kinase 0.0104 0.0001 0.0002
Schistosoma mansoni serine/threonine protein kinase 0.0375 0.0397 0.124
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0443 0.0495 0.0482
Echinococcus granulosus tyrosine protein kinase Src42A 0.0157 0.0078 0.0244
Schistosoma mansoni serine/threonine protein kinase 0.0333 0.0335 0.1045
Giardia lamblia Aurora kinase 0.0209 0.0154 0.14
Loa Loa (eye worm) TK protein kinase 0.0208 0.0152 0.0138
Trichomonas vaginalis AGC family protein kinase 0.0126 0.0032 0.03
Giardia lamblia Kinase, STE STE20 0.018 0.0111 0.0991
Loa Loa (eye worm) hypothetical protein 0.0121 0.0026 0.0012
Echinococcus multilocularis mitogen activated protein kinase 11 0.0223 0.0175 0.0463
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0126 0.0032 0.03
Trypanosoma brucei protein kinase, putative 0.0161 0.0083 0.0864
Trypanosoma brucei protein kinase, putative 0.0186 0.0121 0.1257
Trichomonas vaginalis CAMK family protein kinase 0.0189 0.0125 0.1179
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0209 0.0154 0.0523
Entamoeba histolytica protein kinase, putative 0.04 0.0433 0.1474
Brugia malayi serine/threonine-protein kinase plk-2 0.0341 0.0347 0.0333
Echinococcus granulosus tyrosine protein kinase shark 0.0589 0.0709 0.2214
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.015 0.0068 0.0699
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0693 0.086 0.0848
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Echinococcus granulosus tyrosine protein kinase ABL1 0.0351 0.0362 0.1131
Plasmodium falciparum calcium-dependent protein kinase 3 0.0194 0.0132 0.1376
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0202 0.0144 0.1499
Trichomonas vaginalis serine/threonine-protein kinase ypk, putative 0.0112 0.0012 0.0108
Trypanosoma brucei aurora B kinase 0.0209 0.0154 0.1604
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0336 0.0339 0.3541
Trichomonas vaginalis CAMK family protein kinase 0.0341 0.0347 0.3291
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0012 0.0108
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0267 0.0239 0.0226
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0199 0.014 0.1453
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0012 0.0108
Schistosoma mansoni vam6/vps39 related 0.0336 0.0339 0.106
Loa Loa (eye worm) thyroid receptor interactor 0.0273 0.0248 0.0234
Plasmodium vivax cyclin dependent kinase 7 (cdk7), putative 0.0133 0.0043 0.0438
Loa Loa (eye worm) TK protein kinase 0.0163 0.0087 0.0073
Echinococcus granulosus N chimaerin 0.0122 0.0027 0.0086
Echinococcus granulosus microtubule associated protein 2 0.0833 0.1066 0.333
Loa Loa (eye worm) hypothetical protein 0.0154 0.0074 0.006
Trichomonas vaginalis CMGC family protein kinase 0.0202 0.0144 0.1364
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0208 0.0153 0.0478
Echinococcus multilocularis titin 0.0116 0.0019 0.005
Onchocerca volvulus Tyrosine kinase homolog 0.042 0.0462 0.1393
Schistosoma mansoni serine/threonine kinase 0.0557 0.0663 0.2071
Loa Loa (eye worm) hypothetical protein 0.0156 0.0077 0.0063
Echinococcus multilocularis c src tyrosine kinase 0.0172 0.01 0.0264
Loa Loa (eye worm) gastrulation defective protein 1 0.028 0.0258 0.0244
Trypanosoma cruzi casein kinase II, putative 0.0161 0.0084 0.0872
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0194 0.0132 0.0414
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0109 0.0008 0.0075
Schistosoma mansoni serine/threonine protein kinase 0.0252 0.0216 0.0676
Echinococcus multilocularis casein kinase ii subunit alpha 0.0161 0.0084 0.0222
Schistosoma mansoni protein kinase 0.0783 0.0993 0.3101
Schistosoma mansoni tyrosine kinase 0.0377 0.0399 0.1247
Echinococcus multilocularis raf serine:threonine protein kinase 0.0131 0.004 0.0105
Echinococcus multilocularis dual specificity 0.0375 0.0397 0.1049
Brugia malayi Protein kinase domain containing protein 0.0281 0.0259 0.0245
Loa Loa (eye worm) hypothetical protein 0.0132 0.0042 0.0028
Echinococcus multilocularis serine:threonine protein kinase N2 0.0414 0.0454 0.1199
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.015 0.0068 0.0699
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0221 0.0171 0.0453
Echinococcus multilocularis N chimaerin 0.0122 0.0027 0.0073
Trichomonas vaginalis STE family protein kinase 0.0199 0.014 0.1322
Echinococcus multilocularis expressed protein 0.0143 0.0058 0.0153
Brugia malayi Protein kinase domain 0.018 0.0111 0.0097
Echinococcus granulosus cyclin dependent kinase 5 0.0738 0.0927 0.2895
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Loa Loa (eye worm) TK/INSR protein kinase 0.0495 0.0572 0.0559
Trichomonas vaginalis STE family protein kinase 0.018 0.0111 0.1052
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0351 0.0362 0.0956
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0255 0.0222 0.0692
Echinococcus multilocularis neuroglian 0.0141 0.0055 0.0145
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0229 0.0183 0.0571
Schistosoma mansoni protein kinase 0.0606 0.0734 0.2292
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0161 0.0084 0.0867
Loa Loa (eye worm) hypothetical protein 0.0342 0.0348 0.0335
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0012 0.0108
Trypanosoma cruzi NIMA-related kinase, putative 0.0109 0.0008 0.0075
Brugia malayi Furin-like cysteine rich region family protein 0.0667 0.0823 0.081
Giardia lamblia Kinase, CMGC GSK 0.0758 0.0957 0.9091
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0194 0.0132 0.0119
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0209 0.0154 0.1604
Trichomonas vaginalis AGC family protein kinase 0.0126 0.0032 0.03
Echinococcus granulosus c-Jun N-terminal kinases 0.0334 0.0337 0.1054
Echinococcus multilocularis mitogen activated protein kinase 14 0.0223 0.0175 0.0463
Entamoeba histolytica protein kinase, putative 0.0209 0.0154 0.0523
Brugia malayi Immunoglobulin I-set domain containing protein 0.0299 0.0286 0.0272
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0225 0.0178 0.0555
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0694 0.0863 0.9023
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0295 0.028 0.0876
Schistosoma mansoni tyrosine kinase 0.0172 0.01 0.0312
Schistosoma mansoni serine/threonine protein kinase 0.0504 0.0584 0.1826
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Trypanosoma brucei polo-like protein kinase 0.0341 0.0347 0.3617
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1096 0.145 0.4529
Echinococcus multilocularis dual specificity 0.0202 0.0144 0.0381
Schistosoma mansoni hypothetical protein 0.0162 0.0086 0.0269
Trichomonas vaginalis CMGC family protein kinase 0.0144 0.0059 0.0553
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0012 0.0108
Loa Loa (eye worm) AGC/AKT protein kinase 0.04 0.0433 0.0419
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.216 0.3005 0.9386
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0694 0.0863 0.2696
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0008 0.0025
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0141 0.0055 0.0041
Brugia malayi casein kinase I 0.0251 0.0216 0.0202
Plasmodium falciparum calcium-dependent protein kinase 1 0.0194 0.0132 0.1376
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0121 0.0026 0.0069
Schistosoma mansoni cell adhesion molecule 0.0143 0.0058 0.018
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0341 0.0347 0.0916
Echinococcus multilocularis death associated protein kinase 1 0.2694 0.3784 1
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0375 0.0397 0.0384
Echinococcus multilocularis casein kinase I delta 0.0251 0.0216 0.057
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.013 0.0039 0.0103
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0202 0.0144 0.1499
Schistosoma mansoni tyrosine kinase 0.0667 0.0823 0.2571
Brugia malayi Protein kinase domain containing protein 0.0267 0.0239 0.0226
Plasmodium vivax calcium-dependent protein kinase, putative 0.0194 0.0132 0.1376
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0447 0.0502 0.1568
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0221 0.0171 0.1784
Onchocerca volvulus Serine\/threonine kinase homolog 0.0341 0.0347 0.103
Echinococcus multilocularis Immunoglobulin 0.0121 0.0026 0.0069
Brugia malayi casein kinase 1, delta 0.0251 0.0216 0.0202
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0144 0.0059 0.0608
Mycobacterium ulcerans hypothetical protein 0.0107 0.0006 0.5
Trichomonas vaginalis CAMK family protein kinase 0.015 0.0068 0.0636
Trichomonas vaginalis CAMK family protein kinase 0.0194 0.0132 0.1252
Entamoeba histolytica protein kinase domain containing protein 0.2109 0.293 1
Entamoeba histolytica protein kinase domain containing protein 0.0209 0.0154 0.0523
Entamoeba histolytica PH domain containing protein kinase, putative 0.0708 0.0883 0.3013
Brugia malayi Cam kinase protein 1 0.0194 0.0132 0.0119
Trichomonas vaginalis CAMK family protein kinase 0.015 0.0068 0.0636
Echinococcus granulosus tyrosine kinase 0.0132 0.0042 0.0131
Schistosoma mansoni serine/threonine protein kinase 0.015 0.0068 0.0211
Giardia lamblia Kinase, CDC7 0.0823 0.1051 1
Schistosoma mansoni tyrosine kinase 0.0589 0.0709 0.2214
Leishmania major protein kinase, putative 0.0201 0.0142 0.1477
Echinococcus granulosus roundabout 2 0.0163 0.0087 0.0271
Trypanosoma cruzi cdc2-related kinase 1 0.0738 0.0927 0.9689
Trichomonas vaginalis CAMK family protein kinase 0.015 0.0068 0.0636
Echinococcus multilocularis cyclin dependent kinase 5 0.0738 0.0927 0.2449
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0252 0.0216 0.0203
Echinococcus multilocularis casein kinase I alpha 0.0251 0.0216 0.057
Trichomonas vaginalis AGC family protein kinase 0.0126 0.0032 0.03
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0133 0.0043 0.0029
Brugia malayi Protein kinase domain containing protein 0.0222 0.0173 0.0159
Schistosoma mansoni serine/threonine protein kinase 0.0504 0.0584 0.1826
Onchocerca volvulus 0.0132 0.0042 0.0073
Loa Loa (eye worm) TK/FER protein kinase 0.0132 0.0042 0.0028
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0194 0.0132 0.1376
Echinococcus multilocularis cyclin dependent kinase 9 0.0333 0.0335 0.0884
Brugia malayi protein unc-22 0.0116 0.0019 0.0005
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0202 0.0144 0.1499
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0265 0.0235 0.0622
Echinococcus granulosus Immunoglobulin 0.0121 0.0026 0.0082
Echinococcus multilocularis casein kinase I delta 0.0251 0.0216 0.057
Leishmania major protein kinase, putative 0.0109 0.0008 0.0075
Schistosoma mansoni protein kinase 0.0133 0.0043 0.0133
Trichomonas vaginalis AGC family protein kinase 0.04 0.0433 0.4109
Schistosoma mansoni serine/threonine protein kinase 0.0209 0.0154 0.0482
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0502 0.0582 0.1537
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0194 0.0132 0.1376
Giardia lamblia Kinase, PLK 0.0341 0.0347 0.3245
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0589 0.0709 0.0696
Loa Loa (eye worm) AGC/PKN protein kinase 0.0669 0.0826 0.0813
Echinococcus multilocularis 0.0653 0.0803 0.2122
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0179 0.011 0.0096
Trichomonas vaginalis CMGC family protein kinase 0.0202 0.0144 0.1364
Entamoeba histolytica serine/threonine protein kinase, putative 0.0341 0.0347 0.118
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0359 0.0373 0.0985
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Plasmodium vivax unspecified product 0.0161 0.0084 0.0872
Loa Loa (eye worm) TK protein kinase 0.0225 0.0178 0.0164
Schistosoma mansoni hypothetical protein 0.0162 0.0086 0.0269
Giardia lamblia Kinase, CAMK CAMKL 0.0133 0.0043 0.0332
Trichomonas vaginalis AGC family protein kinase 0.0209 0.0154 0.1459
Brugia malayi map kinase activated protein kinase protein 2 0.0472 0.0538 0.0524
Onchocerca volvulus 0.2205 0.3069 0.9586
Brugia malayi putative serine/threonine kinase SADA gamma 0.015 0.0068 0.0054
Leishmania major protein kinase A catalytic subunit isoform 2 0.0694 0.0863 0.9023
Toxoplasma gondii AGC kinase 0.0694 0.0863 0.9023
Entamoeba histolytica protein kinase domain containing protein 0.0758 0.0957 0.3263
Echinococcus granulosus protein kinase C gamma type 0.0298 0.0285 0.0889
Trichomonas vaginalis CMGC family protein kinase 0.0738 0.0927 0.8814
Brugia malayi Protein kinase domain containing protein 0.0371 0.039 0.0377
Schistosoma mansoni nephrin 0.0148 0.0064 0.0201
Trichomonas vaginalis AGC family protein kinase 0.0199 0.014 0.1322
Trichomonas vaginalis CMGC family protein kinase 0.0202 0.0144 0.1364
Trichomonas vaginalis AGC family protein kinase 0.0291 0.0273 0.2594
Onchocerca volvulus 0.0342 0.0348 0.1036
Loa Loa (eye worm) hypothetical protein 0.0199 0.014 0.0126
Trichomonas vaginalis CMGC family protein kinase 0.0202 0.0144 0.1364
Onchocerca volvulus 0.2295 0.3201 1
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0341 0.0347 0.1083
Trypanosoma brucei Casein kinase II 0.0161 0.0084 0.0872
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0694 0.0863 0.2696
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0317 0.0312 0.0298
Brugia malayi Protein kinase domain containing protein 0.0255 0.0222 0.0208
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0783 0.0993 0.3101
Trichomonas vaginalis AGC family protein kinase 0.0133 0.0043 0.0398
Schistosoma mansoni serine/threonine protein kinase 0.0141 0.0055 0.0173
Giardia lamblia Kinase, CAMK CAMKL 0.0192 0.013 0.1166
Trichomonas vaginalis STE family protein kinase 0.018 0.0111 0.1052
Brugia malayi C1-like domain containing protein 0.0432 0.048 0.0467
Loa Loa (eye worm) hypothetical protein 0.0285 0.0265 0.0252
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0132 0.0041 0.0027
Trichomonas vaginalis CMGC family protein kinase 0.0202 0.0144 0.1364
Echinococcus multilocularis nervana 2 0.0131 0.0039 0.0104
Echinococcus granulosus serine:threonine kinase SAD 1 0.015 0.0068 0.0211
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0453 0.0511 0.1597
Echinococcus multilocularis protein kinase c iota type 0.0403 0.0438 0.1157
Onchocerca volvulus 0.033 0.033 0.0979
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0265 0.0235 0.0735
Schistosoma mansoni tyrosine kinase 0.0527 0.0618 0.1931
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0375 0.0397 0.4146
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Schistosoma mansoni serine/threonine protein kinase 0.0738 0.0927 0.2895
Giardia lamblia Kinase, CMGC MAPK 0.0144 0.0059 0.0488
Echinococcus granulosus cyclin dependent kinase 1 0.0738 0.0927 0.2895
Plasmodium falciparum NIMA related kinase 4 0.0109 0.0008 0.0075
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Trichomonas vaginalis AGC family protein kinase 0.0133 0.0043 0.0398
Echinococcus granulosus cyclin dependent kinase 9 0.0375 0.0397 0.1239
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.2109 0.293 0.7742
Schistosoma mansoni serine/threonine protein kinase 0.0144 0.0059 0.0184
Echinococcus granulosus activin receptor type 0.0161 0.0083 0.0261
Echinococcus granulosus hypothetical protein 0.0653 0.0803 0.2509
Trichomonas vaginalis CMGC family protein kinase 0.0161 0.0084 0.0793
Brugia malayi Immunoglobulin I-set domain containing protein 0.0116 0.0019 0.0005
Trichomonas vaginalis AGC family protein kinase 0.0126 0.0032 0.03
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Brugia malayi Temporarily assigned gene name protein 59 0.0336 0.0339 0.0326
Trypanosoma cruzi aurora B kinase, putative 0.0209 0.0154 0.1604
Brugia malayi p70 ribosomal S6 kinase beta 0.0386 0.0412 0.0399
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0012 0.0108
Schistosoma mansoni protein kinase 0.0251 0.0216 0.0673
Echinococcus granulosus serine:threonine protein kinase N2 0.0414 0.0454 0.1417
Schistosoma mansoni protein kinase 0.018 0.0111 0.0348
Loa Loa (eye worm) hypothetical protein 0.0194 0.0132 0.0119
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0259 0.0227 0.0213
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.2109 0.293 0.292
Echinococcus granulosus protein kinase 0.0606 0.0734 0.2292
Trichomonas vaginalis CMGC family protein kinase 0.0738 0.0927 0.8814
Plasmodium falciparum calcium-dependent protein kinase 4 0.0194 0.0132 0.1376
Echinococcus granulosus CDC7 cell division cycle 7 0.0823 0.1051 0.3285
Entamoeba histolytica protein kinase, putative 0.0386 0.0412 0.1405
Trypanosoma brucei Serine/threonine-protein kinase NEK11, putative 0.0109 0.0008 0.0075
Brugia malayi serine/threonine protein kinase 6 0.0209 0.0154 0.014
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0223 0.0175 0.1824
Echinococcus multilocularis rho associated protein kinase 0.2295 0.3201 0.846
Brugia malayi MAP kinase sur-1 0.0144 0.0059 0.0045
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0192 0.013 0.1348
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.018 0.0111 0.0348
Brugia malayi Fes/CIP4 homology domain containing protein 0.0273 0.0248 0.0234
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0538 0.0634 0.1676
Entamoeba histolytica protein kinase, putative 0.0194 0.0132 0.0449
Plasmodium vivax tyrosine kinase-like protein, putative 0.0141 0.0055 0.0564
Leishmania major protein kinase, putative,serine/threonine-protein kinase Nek1, putative 0.0109 0.0008 0.0075
Trichomonas vaginalis CAMK family protein kinase 0.0353 0.0364 0.3454
Entamoeba histolytica casein kinase, putative 0.0161 0.0084 0.0285
Schistosoma mansoni serine/threonine protein kinase 0.0669 0.0826 0.2582
Echinococcus granulosus tyrosine protein kinase Src42A 0.0265 0.0235 0.0735
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0113 0.0014 0.0138
Plasmodium vivax serine/threonine kinase-1, putative 0.0744 0.0935 0.9774
Brugia malayi Protein kinase domain containing protein 0.0133 0.0043 0.0029
Loa Loa (eye worm) hypothetical protein 0.0156 0.0077 0.0063
Trichomonas vaginalis AGC family protein kinase 0.0133 0.0043 0.0398
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0201 0.0142 0.1477
Loa Loa (eye worm) TK/ABL protein kinase 0.0351 0.0362 0.0348
Brugia malayi Egg laying defective protein 4 0.0198 0.0137 0.0123
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0344 0.0351 0.0928
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0144 0.0059 0.0608
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0194 0.0132 0.1376
Schistosoma mansoni serine/threonine protein kinase 0.0744 0.0935 0.2921
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0606 0.0734 0.0721
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0758 0.0957 0.2988
Schistosoma mansoni protein kinase 0.018 0.0111 0.0348
Schistosoma mansoni tyrosine kinase 0.0137 0.0049 0.0153
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.029 0.0272 0.0259
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0012 0.0108
Trichomonas vaginalis CAMK family protein kinase 0.015 0.0068 0.0636
Loa Loa (eye worm) TK/FER protein kinase 0.0132 0.0042 0.0028
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0694 0.0863 0.9023
Brugia malayi cyclin-dependent kinase 7 homolog 0.0546 0.0646 0.0633
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0141 0.0055 0.0564
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0141 0.0055 0.0147
Trypanosoma cruzi Mitogen-activated protein kinase 10, putative 0.0133 0.0043 0.0438
Echinococcus multilocularis expressed conserved protein 0.0198 0.0137 0.0363
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Trichomonas vaginalis AGC family protein kinase 0.0126 0.0032 0.03
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0295 0.028 0.0741
Loa Loa (eye worm) hypothetical protein 0.0851 0.1092 0.108
Echinococcus multilocularis cyclin dependent kinase 1 0.0738 0.0927 0.2449
Echinococcus granulosus serine:threonine protein kinase NLK 0.0133 0.0043 0.0133
Schistosoma mansoni serine/threonine protein kinase 0.0538 0.0634 0.1981
Giardia lamblia Kinase, CMGC SRPK 0.0143 0.0058 0.0479
Brugia malayi intracellular kinase 0.0758 0.0957 0.0944
Schistosoma mansoni serine/threonine protein kinase 0.0371 0.039 0.1218
Entamoeba histolytica protein kinase domain containing protein 0.0133 0.0043 0.0143
Toxoplasma gondii NEK kinase 0.0109 0.0008 0.0075
Loa Loa (eye worm) casein kinase 0.019 0.0127 0.0113
Schistosoma mansoni tyrosine kinase 0.0265 0.0235 0.0735
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0132 0.0042 0.0141
Brugia malayi hypothetical protein 0.0128 0.0035 0.0021
Entamoeba histolytica protein kinase domain containing protein 0.0333 0.0335 0.1139
Giardia lamblia Kinase, CK1 Casein kinase 0.0251 0.0216 0.1989
Brugia malayi Immunoglobulin I-set domain containing protein 0.0128 0.0035 0.0021
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0336 0.0339 0.106
Echinococcus multilocularis protein kinase c epsilon type 0.0317 0.0312 0.0824
Echinococcus multilocularis tyrosine protein kinase shark 0.0589 0.0709 0.1873
Echinococcus multilocularis cyclin dependent kinase 7 0.0504 0.0584 0.1544
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0738 0.0927 0.0914
Trichomonas vaginalis serine/threonine-protein kinase, putative 0.0112 0.0012 0.0108
Echinococcus multilocularis tyrosine kinase 0.0132 0.0042 0.0111
Trichomonas vaginalis CAMK family protein kinase 0.0189 0.0125 0.1179
Echinococcus multilocularis myosin iiia 0.0201 0.0142 0.0375
Trichomonas vaginalis AGC family protein kinase 0.0126 0.0032 0.03
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0161 0.0083 0.0261
Toxoplasma gondii CMGC kinase, CK2 family 0.0161 0.0084 0.0872
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0334 0.0337 0.0324
Schistosoma mansoni serine/threonine protein kinase 0.0198 0.0137 0.0429
Echinococcus granulosus rho-associated protein kinase 1 0.2295 0.3201 1
Echinococcus granulosus titin 0.0116 0.0019 0.0059
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0143 0.0058 0.0597
Schistosoma mansoni serine/threonine protein kinase 0.0295 0.028 0.0876
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0161 0.0083 0.0864
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0344 0.0351 0.0338
Entamoeba histolytica PH domain containing protein kinase, putative 0.0235 0.0192 0.0651
Trichomonas vaginalis AGC family protein kinase 0.0126 0.0032 0.03
Trypanosoma brucei Mitogen-activated protein kinase 10, putative 0.0133 0.0043 0.0438
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0201 0.0142 0.1477
Brugia malayi Cell division protein kinase 2 0.0133 0.0043 0.0029
Schistosoma mansoni tyrosine kinase 0.0377 0.0399 0.1247
Echinococcus granulosus calcium activated potassium channel 0.0253 0.0218 0.0681
Schistosoma mansoni serine/threonine protein kinase 0.0359 0.0373 0.1165
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0144 0.0059 0.0608
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0223 0.0175 0.0161
Loa Loa (eye worm) AGC/PKG protein kinase 0.0198 0.0137 0.0123
Schistosoma mansoni serine/threonine protein kinase 0.0359 0.0373 0.1165
Trichomonas vaginalis AGC family protein kinase 0.0126 0.0032 0.03
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.015 0.0068 0.0699
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0194 0.0132 0.1376
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Echinococcus multilocularis serine:threonine protein kinase NLK 0.0133 0.0043 0.0113
Trichomonas vaginalis CAMK family protein kinase 0.015 0.0068 0.0636
Giardia lamblia Kinase, CMGC CDK 0.0738 0.0927 0.8806
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0161 0.0083 0.0864
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0336 0.0339 0.106
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0161 0.0083 0.0864
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0221 0.0171 0.1784
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.027 0.0243 0.0641
Echinococcus granulosus tyrosine protein kinase Fyn 0.0265 0.0235 0.0735
Schistosoma mansoni serine/threonine protein kinase 0.0251 0.0216 0.0673
Trypanosoma cruzi casein kinase, putative 0.0251 0.0216 0.2246
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0604 0.0731 0.1933
Echinococcus granulosus cGMP dependent protein kinase 1 0.0198 0.0137 0.0429
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0161 0.0084 0.0872
Entamoeba histolytica serine/threonine protein kinase, putative 0.0109 0.0008 0.0024
Onchocerca volvulus 0.0132 0.0042 0.0073
Brugia malayi Protein kinase domain containing protein 0.0375 0.0397 0.0384
Giardia lamblia Kinase, AGC PKA 0.0694 0.0863 0.8195
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Trichomonas vaginalis AGC family protein kinase 0.0126 0.0032 0.03
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0012 0.0108
Loa Loa (eye worm) SRC-1 0.0265 0.0235 0.0222
Trichomonas vaginalis AGC family protein kinase 0.0694 0.0863 0.8208
Brugia malayi Protein kinase domain containing protein 0.04 0.0433 0.0419
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0336 0.0339 0.0897
Schistosoma mansoni kinase 0.0333 0.0335 0.1045
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0783 0.0993 0.2623
Echinococcus granulosus nervana 2 0.0131 0.0039 0.0123
Trichomonas vaginalis AGC family protein kinase 0.0126 0.0032 0.03
Entamoeba histolytica protein kinase, putative 0.0209 0.0154 0.0523
Schistosoma mansoni protein kinase 0.0942 0.1224 0.3824
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0109 0.0008 0.0075
Echinococcus granulosus raf serine:threonine protein kinase 0.0131 0.004 0.0124
Echinococcus multilocularis activin receptor type 0.0161 0.0083 0.0221
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0689 0.0855 0.0842
Schistosoma mansoni tyrosine kinase 0.0377 0.0399 0.1247
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0375 0.0397 0.4146
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.013 0.0039 0.0122
Brugia malayi serine/threonine-protein kinase 6 0.0209 0.0154 0.014
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0694 0.0863 0.9023
Leishmania major protein kinase, putative 0.0161 0.0083 0.0864
Echinococcus granulosus mitogen activated protein kinase 15 0.0133 0.0043 0.0133
Trichomonas vaginalis CAMK family protein kinase 0.015 0.0068 0.0636
Plasmodium vivax serine/threonine-protein kinase NEK4, putative 0.0109 0.0008 0.0075
Schistosoma mansoni protein kinase 0.0259 0.0227 0.071
Schistosoma mansoni serine/threonine protein kinase 0.015 0.0068 0.0211
Trichomonas vaginalis CMGC family protein kinase 0.0202 0.0144 0.1364
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0201 0.0142 0.0482
Loa Loa (eye worm) AUR protein kinase 0.0209 0.0154 0.014
Schistosoma mansoni serine/threonine protein kinase 0.0253 0.0218 0.0681
Loa Loa (eye worm) CAMK protein kinase 0.0116 0.0019 0.0005
Trichomonas vaginalis CMGC family protein kinase 0.0133 0.0043 0.0398
Trypanosoma cruzi Mitogen-activated protein kinase 10, putative 0.0133 0.0043 0.0438
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0295 0.028 0.0741
Brugia malayi SRC-1 0.0265 0.0235 0.0222
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0229 0.0183 0.0169
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0225 0.0178 0.047
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0012 0.0108
Plasmodium falciparum NIMA related kinase 2 0.0109 0.0008 0.0075
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0577 0.0692 0.2162
Trypanosoma brucei NIMA-related protein kinase 0.0109 0.0008 0.0075
Schistosoma mansoni serine/threonine protein kinase 0.0694 0.0863 0.2696
Schistosoma mansoni serine/threonine protein kinase 0.0253 0.0218 0.0681
Leishmania major casein kinase II, putative 0.0161 0.0084 0.0872
Brugia malayi Protein kinase domain containing protein 0.0132 0.0042 0.0028
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0223 0.0175 0.1824
Trichomonas vaginalis CMGC family protein kinase 0.0823 0.1051 1
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0184 0.0117 0.0104
Plasmodium falciparum protein serine/threonine kinase-1 0.0744 0.0935 0.9774
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0194 0.0132 0.035
Loa Loa (eye worm) TK/FER protein kinase 0.0132 0.0042 0.0028
Brugia malayi SH2 domain containing protein 0.027 0.0243 0.0229
Entamoeba histolytica hypothetical protein 0.0375 0.0397 0.1353
Toxoplasma gondii aurora kinase 0.0209 0.0154 0.1604
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0738 0.0927 0.0914
Leishmania major protein kinase, putative 0.0744 0.0935 0.9774
Onchocerca volvulus 0.0336 0.0339 0.1007
Echinococcus granulosus epidermal growth factor receptor 0.0447 0.0502 0.1568
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0012 0.0108
Echinococcus multilocularis rac serine:threonine kinase 0.0235 0.0192 0.0506
Trichomonas vaginalis CK1 family protein kinase 0.0251 0.0216 0.2043
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0137 0.0048 0.0151
Entamoeba histolytica cell division protein kinase 2, putative 0.0738 0.0927 0.3162
Trichomonas vaginalis CMGC family protein kinase 0.0823 0.1051 1
Trichomonas vaginalis AGC family protein kinase 0.0126 0.0032 0.03
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.0008 0.0068
Echinococcus multilocularis serine:threonine protein kinase 38 0.0255 0.0222 0.0586
Giardia lamblia Kinase, CMGC GSK 0.0758 0.0957 0.9091
Brugia malayi Tyrosine-protein kinase abl-1 0.0135 0.0046 0.0032
Trichomonas vaginalis CAMK family protein kinase 0.015 0.0068 0.0636
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0251 0.0216 0.0202
Trypanosoma brucei protein kinase, putative 0.0758 0.0957 1
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0209 0.0154 0.0523
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0194 0.0132 0.035
Echinococcus granulosus serine:threonine protein kinase N2 0.0669 0.0826 0.2582
Loa Loa (eye worm) hypothetical protein 0.0133 0.0043 0.0029
Trichomonas vaginalis STE family protein kinase 0.018 0.0111 0.1052
Schistosoma mansoni serine/threonine protein kinase 0.0334 0.0337 0.1054
Trichomonas vaginalis CAMK family protein kinase 0.015 0.0068 0.0636
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0209 0.0154 0.0407
Loa Loa (eye worm) AGC/NDR protein kinase 0.0255 0.0222 0.0208
Echinococcus granulosus serine:threonine protein kinase Chk2 0.013 0.0039 0.0122
Brugia malayi protein kinase C II. 0.0317 0.0312 0.0298
Onchocerca volvulus Serine\/threonine kinase homolog 0.0229 0.0183 0.0516
Echinococcus multilocularis epidermal growth factor receptor 0.0447 0.0502 0.1326
Schistosoma mansoni serine/threonine protein kinase 0.216 0.3005 0.9386
Echinococcus granulosus casein kinase I delta 0.0251 0.0216 0.0673
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0143 0.0058 0.0597
Plasmodium falciparum serine/threonine protein kinase 0.0143 0.0058 0.0597
Entamoeba histolytica protein kinase, putative 0.0143 0.0058 0.0195
Trichomonas vaginalis cAMP-dependent protein kinase catalytic subunit, putative 0.0112 0.0012 0.0108
Trypanosoma cruzi cdc2-related kinase 1 0.0738 0.0927 0.9689
Echinococcus granulosus tyrosine protein kinase Lyn 0.0355 0.0367 0.1147
Echinococcus granulosus twitchin 0.0231 0.0187 0.0584
Loa Loa (eye worm) hypothetical protein 0.0162 0.0086 0.0072
Trypanosoma cruzi Protein kinase B 0.0235 0.0192 0.1995
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0694 0.0863 0.2696
Plasmodium vivax glycogen synthase kinase 3, putative 0.0758 0.0957 1
Entamoeba histolytica protein kinase domain containing protein 0.0202 0.0144 0.0489
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0012 0.0108
Plasmodium falciparum protein kinase, putative 0.0161 0.0083 0.0864
Echinococcus granulosus Cell division cycle 2 protein kinase 0.0133 0.0043 0.0133
Echinococcus multilocularis serine:threonine protein kinase N2 0.0255 0.0222 0.0586
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.0008 0.0068
Trypanosoma cruzi polo-like protein kinase, putative 0.0341 0.0347 0.3617
Echinococcus granulosus aurora kinase A 0.0209 0.0154 0.0482
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0758 0.0957 1
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Trypanosoma brucei cdc2-related kinase 1 0.0738 0.0927 0.9689
Trichomonas vaginalis CAMK family protein kinase 0.0515 0.0601 0.5712
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0198 0.0137 0.0363
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0223 0.0175 0.1824
Entamoeba histolytica protein kinase, putative 0.0171 0.0098 0.0332
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0758 0.0957 0.2528
Loa Loa (eye worm) hypothetical protein 0.0487 0.056 0.0547
Trichomonas vaginalis CMGC family protein kinase 0.0161 0.0084 0.0793
Trichomonas vaginalis CAMK family protein kinase 0.0133 0.0043 0.0398
Schistosoma mansoni serine/threonine protein kinase 0.2109 0.293 0.9152
Brugia malayi Kinase associated domain 1 family protein 0.0162 0.0086 0.0072
Toxoplasma gondii AGC kinase 0.0694 0.0863 0.9023
Onchocerca volvulus 0.0758 0.0957 0.2947
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0144 0.0059 0.0608
Plasmodium vivax serine/threonine protein kinase, putative 0.0143 0.0058 0.0597
Schistosoma mansoni serine/threonine protein kinase 0.0177 0.0107 0.0333
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.018 0.0111 0.0348
Echinococcus multilocularis Immunoglobulin 0.0121 0.0026 0.0069
Echinococcus multilocularis tyrosine protein kinase Abl 0.0256 0.0222 0.0587
Schistosoma mansoni serine/threonine protein kinase 0.029 0.0272 0.0851
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0194 0.0132 0.0414
Trichomonas vaginalis CMGC family protein kinase 0.0161 0.0084 0.0793
Loa Loa (eye worm) hypothetical protein 0.0128 0.0035 0.0021
Schistosoma mansoni tyrosine kinase 0.0495 0.0572 0.1788
Brugia malayi Protein kinase domain containing protein 0.0515 0.0601 0.0588
Giardia lamblia Kinase, CMGC CLK 0.0744 0.0935 0.8883
Loa Loa (eye worm) CAMK/PIM protein kinase 0.216 0.3005 0.2995
Toxoplasma gondii histone kinase SNF1, putative 0.015 0.0068 0.0699
Schistosoma mansoni protein kinase 0.0783 0.0993 0.3101
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0012 0.0108
Brugia malayi cell division control protein 2 homolog 0.0738 0.0927 0.0914
Schistosoma mansoni serine/threonine protein kinase 0.011 0.0009 0.003
Echinococcus granulosus casein kinase i 0.0251 0.0216 0.0673
Trichomonas vaginalis AGC family protein kinase 0.04 0.0433 0.4109
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0265 0.0235 0.0735
Loa Loa (eye worm) TK protein kinase 0.0299 0.0286 0.0272
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0694 0.0863 0.9023
Entamoeba histolytica protein kinase domain containing protein 0.0161 0.0083 0.0282
Brugia malayi Homeodomain interacting protein kinase protein 1 0.2109 0.293 0.292
Trichomonas vaginalis CMGC family protein kinase 0.0144 0.0059 0.0553
Onchocerca volvulus 0.0251 0.0216 0.0618
Echinococcus multilocularis PAK box P21 Rho binding 0.0157 0.0078 0.0206
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0122 0.0027 0.0086

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) > 195 um PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Confirmation HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1). (Class of assay: confirmatory) [Related pubchem assays: 2118 (Project Summary), 2098 (Primary HTS)] ChEMBL. No reference
Potency (functional) 5.2213 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (binding) = 15.8489 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) 26.6795 uM PubChem BioAssay. qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.