Detailed information for compound 1392436

Basic information

Technical information
  • TDR Targets ID: 1392436
  • Name: 6-(2-chlorophenyl)-N-[(5-methylpyrazin-2-yl)m ethyl]quinazolin-4-amine
  • MW: 361.828 | Formula: C20H16ClN5
  • H donors: 1 H acceptors: 4 LogP: 3.9 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1cnc(cn1)CNc1ncnc2c1cc(cc2)c1ccccc1Cl
  • InChi: 1S/C20H16ClN5/c1-13-9-23-15(10-22-13)11-24-20-17-8-14(6-7-19(17)25-12-26-20)16-4-2-3-5-18(16)21/h2-10,12H,11H2,1H3,(H,24,25,26)
  • InChiKey: JGTHNIVRFFDTOL-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

  • 6-(2-chlorophenyl)-N-[(5-methyl-2-pyrazinyl)methyl]-4-quinazolinamine
  • [6-(2-chlorophenyl)quinazolin-4-yl]-[(5-methylpyrazin-2-yl)methyl]amine
  • NCGC00011441
  • PCOP-488493

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens ubiquitin specific peptidase 2 Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 3, subfamily A, polypeptide 4 Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 2, subfamily C, polypeptide 19 Starlite/ChEMBL No references
Homo sapiens mitogen-activated protein kinase 1 Starlite/ChEMBL No references
Homo sapiens thyroid stimulating hormone receptor Starlite/ChEMBL No references
Homo sapiens CDC-like kinase 4 Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 2, subfamily D, polypeptide 6 Starlite/ChEMBL No references
Homo sapiens lamin A/C Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 1, subfamily A, polypeptide 2 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma brucei gambiense mitogen-activated protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus multilocularis Get druggable targets OG5_126990 All targets in OG5_126990
Cryptosporidium hominis MAPK Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum Mitogen-activated protein kinase 3, putative Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum expressed protein Get druggable targets OG5_126990 All targets in OG5_126990
Candida albicans Serine/threonine protein kinase of MAP kinase family Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127431 All targets in OG5_127431
Trypanosoma brucei kinetoplastid kinetochore protein 19 Get druggable targets OG5_126990 All targets in OG5_126990
Leishmania donovani cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) Get druggable targets OG5_127431 All targets in OG5_127431
Candida albicans cytochrome P450 556 Get druggable targets OG5_126554 All targets in OG5_126554
Candida albicans closely related to C.maltosa N-alkane-inducible cytochrome P-450, alkane hydroxylating monooxygenase CYP52A3-b aka P450Alk1A (BA Get druggable targets OG5_126554 All targets in OG5_126554
Trypanosoma brucei gambiense protein kinase, putative,tyrosine protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma brucei protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Brugia malayi Cytochrome P450 family protein Get druggable targets OG5_126582 All targets in OG5_126582
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126990 All targets in OG5_126990
Echinococcus granulosus mitogen activated protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus granulosus ubiquitin specific protease 41 Get druggable targets OG5_127431 All targets in OG5_127431
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania infantum ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania braziliensis mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126554 All targets in OG5_126554
Trypanosoma cruzi cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Echinococcus multilocularis mitogen activated protein kinase 3 Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) cytochrome P450 family protein Get druggable targets OG5_126582 All targets in OG5_126582
Loa Loa (eye worm) CYP4Cod1 Get druggable targets OG5_126554 All targets in OG5_126554
Trypanosoma congolense kinetoplastid kinetochore protein, putative Get druggable targets OG5_126990 All targets in OG5_126990
Schistosoma japonicum ko:K04371 extracellular signal-regulated kinase 1/2, putative Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus multilocularis cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma brucei gambiense cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Trypanosoma cruzi mitogen-activated protein kinase 11, putative Get druggable targets OG5_126781 All targets in OG5_126781
Candida albicans Serine/threonine protein kinase Get druggable targets OG5_126990 All targets in OG5_126990
Leishmania mexicana cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Candida albicans MAP kinase-like orf Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma cruzi cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Schistosoma japonicum IPR015063,Domain of unknown function DUF1873,domain-containing Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania infantum mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania major cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania mexicana Get druggable targets OG5_126990 All targets in OG5_126990
Schistosoma japonicum Ubiquitin carboxyl-terminal hydrolase 8, putative Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma mansoni intermediate filament proteins Get druggable targets OG5_128723 All targets in OG5_128723
Candida albicans similar to C.maltosa N-alkane inducible cytochrome P-450, ALK8 CYP52A11 Get druggable targets OG5_126554 All targets in OG5_126554
Plasmodium yoelii protein serine/threonine kinase-1 Get druggable targets OG5_126990 All targets in OG5_126990
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 Get druggable targets OG5_127431 All targets in OG5_127431
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative Get druggable targets OG5_126990 All targets in OG5_126990
Candida albicans Serine/threonine protein kinase Get druggable targets OG5_126990 All targets in OG5_126990
Leishmania infantum protein kinase, putative Get druggable targets OG5_126990 All targets in OG5_126990
Plasmodium vivax serine/threonine kinase-1, putative Get druggable targets OG5_126990 All targets in OG5_126990
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum hypothetical protein Get druggable targets OG5_127431 All targets in OG5_127431
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative Get druggable targets OG5_126990 All targets in OG5_126990
Echinococcus multilocularis ubiquitin specific protease 41 Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania mexicana ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative Get druggable targets OG5_127431 All targets in OG5_127431
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative Get druggable targets OG5_127431 All targets in OG5_127431
Cryptosporidium parvum ubiquitin C-terminal hydrolase of the cysteine proteinase fold Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania mexicana mitogen-activated protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Plasmodium berghei serine/threonine kinase-1, putative Get druggable targets OG5_126990 All targets in OG5_126990
Brugia malayi Protein kinase domain containing protein Get druggable targets OG5_126990 All targets in OG5_126990
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus granulosus intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Candida albicans Serine/threonine protein kinase of MAP kinase family Get druggable targets OG5_126781 All targets in OG5_126781
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania donovani ubiquitin carboxyl-terminal hydrolase, putative Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma japonicum ko:K01072 ubiquitin thiolesterase [EC3.1.2.15], putative Get druggable targets OG5_127431 All targets in OG5_127431
Brugia malayi Cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative Get druggable targets OG5_126990 All targets in OG5_126990
Trypanosoma brucei cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Leishmania braziliensis protein kinase, putative Get druggable targets OG5_126990 All targets in OG5_126990
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) Get druggable targets OG5_127431 All targets in OG5_127431
Trypanosoma congolense tyrosine protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Brugia malayi Intermediate filament tail domain containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Theileria parva serine/threonine protein kinase, putative Get druggable targets OG5_126990 All targets in OG5_126990
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi MAP kinase sur-1 Get druggable targets OG5_126781 All targets in OG5_126781
Neospora caninum hypothetical protein Get druggable targets OG5_126990 All targets in OG5_126990
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative Get druggable targets OG5_126990 All targets in OG5_126990
Brugia malayi Cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Leishmania braziliensis mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440,map kinase Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma brucei gambiense ubiquitin carboxyl-terminal hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative Get druggable targets OG5_127431 All targets in OG5_127431
Candida albicans MAP kinase-like orf Get druggable targets OG5_126781 All targets in OG5_126781
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma japonicum IPR001394,Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2,domain-containing Get druggable targets OG5_127431 All targets in OG5_127431
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative Get druggable targets OG5_127431 All targets in OG5_127431
Trypanosoma congolense kinetoplastid kinetochore protein 10, putative Get druggable targets OG5_126990 All targets in OG5_126990
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126990 All targets in OG5_126990
Trypanosoma congolense cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Leishmania infantum mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Plasmodium knowlesi serine/threonine kinase-1, putative Get druggable targets OG5_126990 All targets in OG5_126990
Leishmania infantum protein kinase, putative Get druggable targets OG5_126990 All targets in OG5_126990
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 Get druggable targets OG5_127431 All targets in OG5_127431
Candida albicans ubiquitin-specific protease Get druggable targets OG5_127431 All targets in OG5_127431
Loa Loa (eye worm) cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Echinococcus granulosus hypothetical protein Get druggable targets OG5_126990 All targets in OG5_126990
Giardia lamblia Kinase, CMGC MAPK Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126990 All targets in OG5_126990
Schistosoma japonicum Intermediate filament protein ifa-1, putative Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis mitogen activated protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum Serine/threonine-protein kinase Doa, putative Get druggable targets OG5_126990 All targets in OG5_126990
Leishmania braziliensis cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Trypanosoma cruzi mitogen activated protein kinase 2, putative Get druggable targets OG5_126781 All targets in OG5_126781
Cryptosporidium parvum serine/threonine kinase-1 Get druggable targets OG5_126990 All targets in OG5_126990
Leishmania infantum cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Schistosoma japonicum expressed protein Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus granulosus dual specificity protein kinase clk2 Get druggable targets OG5_126990 All targets in OG5_126990
Schistosoma japonicum Mitogen-activated protein kinase 3, putative Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum Lamin-C, putative Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania mexicana mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 Get druggable targets OG5_126554 All targets in OG5_126554
Echinococcus granulosus lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) CMGC/CLK protein kinase Get druggable targets OG5_126990 All targets in OG5_126990
Echinococcus multilocularis lamin Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Leishmania major protein kinase, putative Get druggable targets OG5_126990 All targets in OG5_126990
Trypanosoma congolense ubiquitin carboxyl-terminal hydrolase, putative Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania major mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania donovani mitogen-activated protein kinase 4 Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus granulosus mitogen activated protein kinase 3 Get druggable targets OG5_126781 All targets in OG5_126781
Giardia lamblia Kinase, CMGC CLK Get druggable targets OG5_126990 All targets in OG5_126990
Echinococcus granulosus lamin Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania donovani mitogen activated protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus multilocularis musashi Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) intermediate filament tail domain-containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum ko:K08823 CDC-like kinase, putative Get druggable targets OG5_126990 All targets in OG5_126990
Candida albicans cytochrome P450 56 Get druggable targets OG5_126554 All targets in OG5_126554
Trypanosoma brucei gambiense protein kinase, putative Get druggable targets OG5_126990 All targets in OG5_126990
Trypanosoma brucei mitogen activated protein kinase 4, putative Get druggable targets OG5_126781 All targets in OG5_126781
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_127431 All targets in OG5_127431
Loa Loa (eye worm) follicle stimulating hormone receptor Get druggable targets OG5_130089 All targets in OG5_130089
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania braziliensis ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania mexicana protein kinase, putative Get druggable targets OG5_126990 All targets in OG5_126990
Trypanosoma cruzi mitogen-activated protein kinase 11, putative Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus granulosus cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma cruzi mitogen activated protein kinase 4, putative Get druggable targets OG5_126781 All targets in OG5_126781
Cryptosporidium parvum MAPK, putative Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma congolense kinetoplastid kinetochore protein, putative Get druggable targets OG5_126990 All targets in OG5_126990
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative Get druggable targets OG5_126990 All targets in OG5_126990
Schistosoma japonicum Ubiquitin carboxyl-terminal hydrolase 8, putative Get druggable targets OG5_127431 All targets in OG5_127431
Candida albicans MAP kinase implicated in PKC1-controlled signalling pathway Get druggable targets OG5_126781 All targets in OG5_126781
Brugia malayi follicle stimulating hormone receptor Get druggable targets OG5_130089 All targets in OG5_130089
Cryptosporidium hominis serine/threonine kinase-1 Get druggable targets OG5_126990 All targets in OG5_126990
Loa Loa (eye worm) intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Babesia bovis protein serine/threonine kinase 1 Get druggable targets OG5_126990 All targets in OG5_126990
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania major protein kinase, putative Get druggable targets OG5_126990 All targets in OG5_126990
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein Get druggable targets OG5_127431 All targets in OG5_127431
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Brugia malayi intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative Get druggable targets OG5_127431 All targets in OG5_127431
Trypanosoma brucei kinetoplastid kinetochore protein 10 Get druggable targets OG5_126990 All targets in OG5_126990
Plasmodium falciparum protein serine/threonine kinase-1 Get druggable targets OG5_126990 All targets in OG5_126990
Candida albicans similar to C.maltosa N-alkane inducible cytochrome P-450, ALK8 CYP52A11 Get druggable targets OG5_126554 All targets in OG5_126554
Schistosoma japonicum ko:K07611 lamin, putative Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126990 All targets in OG5_126990
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Cryptosporidium hominis ubiquitin specific protease 66 Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus multilocularis dual specificity protein kinase clk2 Get druggable targets OG5_126990 All targets in OG5_126990
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Leishmania major cytochrome p450-like protein cytochrome P450, family 2, subfamily C, polypeptide 19 490 aa 411 aa 23.1 %
Plasmodium falciparum ubiquitin specific protease, putative ubiquitin specific peptidase 2 362 aa 378 aa 25.7 %
Trypanosoma brucei mitogen-activated protein kinase 5 mitogen-activated protein kinase 1 360 aa 361 aa 33.2 %
Brugia malayi cytochrome P450 cytochrome P450, family 3, subfamily A, polypeptide 4 502 aa 492 aa 24.2 %
Brugia malayi Cytochrome P450 family protein cytochrome P450, family 1, subfamily A, polypeptide 2 516 aa 470 aa 26.2 %
Brugia malayi cytochrome P450 cytochrome P450, family 2, subfamily D, polypeptide 6 497 aa 425 aa 32.0 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0249 0.1018 0.3346
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0039 0.0106 0.01
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0066 0.0222 0.0582
Echinococcus multilocularis gamma secretase subunit aph 1 0.0127 0.0491 0.0486
Trypanosoma cruzi metacaspase, putative 0.015 0.059 0.1005
Plasmodium falciparum proteasome subunit beta type-5 0.0192 0.0773 0.2493
Schistosoma mansoni rab 0.0121 0.0465 0.043
Schistosoma mansoni neuronal calcium sensor 0.0121 0.0465 0.043
Loa Loa (eye worm) hypothetical protein 0.0043 0.0122 0.0129
Brugia malayi Cathepsin L-like precursor 0.0689 0.2933 0.3089
Brugia malayi fibroinase precursor 0.0156 0.0615 0.0636
Toxoplasma gondii EF hand domain-containing protein 0.0121 0.0465 0.1479
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0156 0.0615 0.1944
Brugia malayi Cell death protein 3 precursor 0.0041 0.0118 0.011
Trypanosoma brucei metacaspase MCA3 0.015 0.059 0.1584
Giardia lamblia Cathepsin L precursor 0.0156 0.0615 0.2683
Echinococcus multilocularis regulator of G protein signaling 7 0.0039 0.0106 0.01
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0192 0.0773 0.3441
Brugia malayi cathepsin B-like cysteine proteinase 0.1291 0.5548 0.5856
Leishmania major calmodulin-like protein 0.0121 0.0465 0.1225
Entamoeba histolytica calcium-binding protein, putative 0.0121 0.0465 0.1424
Trypanosoma cruzi centrin, putative 0.0121 0.0465 0.0777
Echinococcus multilocularis programmed cell death protein 0.0121 0.0465 0.046
Echinococcus granulosus EF HAND 1 calcium binding site 0.0121 0.0465 0.046
Brugia malayi hypothetical protein 0.039 0.163 0.1711
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0027 0.0055 0.0018
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0027 0.0055 0.0053
Trypanosoma cruzi cytochrome P450, putative 0.0041 0.0114 0.014
Trypanosoma brucei metacaspase MCA2 0.015 0.059 0.1584
Leishmania major phospholipase c-like protein 0.0121 0.0465 0.1225
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0507 0.214 0.3817
Entamoeba histolytica cysteine protease, putative 0.0372 0.1554 0.521
Echinococcus granulosus Tolloid protein 1 0.0035 0.0091 0.0086
Brugia malayi Pre-SET motif family protein 0.0184 0.0738 0.0766
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0069 0.0238 0.0233
Echinococcus granulosus axis inhibition protein axin 0.0039 0.0106 0.01
Schistosoma mansoni intermediate filament proteins 0.0033 0.0079 0.0042
Onchocerca volvulus Cell death protein 3 homolog 0.0041 0.0118 0.0112
Trichomonas vaginalis CMGC family protein kinase 0.0074 0.0257 0.0702
Echinococcus multilocularis EF hand domain containing family member A2 0.0121 0.0465 0.046
Echinococcus granulosus Proteasome subunit alpha type 7 0.0027 0.0055 0.0049
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0156 0.0615 0.1944
Loa Loa (eye worm) hypothetical protein 0.0473 0.1993 0.2105
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0026 0.0052 0.0046
Loa Loa (eye worm) hypothetical protein 0.0689 0.2933 0.3098
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0003
Trichomonas vaginalis calcineurin B subunit, putative 0.0121 0.0465 0.1424
Entamoeba histolytica cysteine proteinase, putative 0.0372 0.1554 0.521
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0039 0.0106 0.0069
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2314 0.9993 1
Brugia malayi regulator of G-protein signaling egl-10 0.0039 0.0106 0.0098
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0041 0.0114 0.1045
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0041 0.0118 0.011
Giardia lamblia Cathepsin B precursor 0.0156 0.0615 0.2683
Schistosoma mansoni aldehyde dehydrogenase 0.0054 0.0171 0.0135
Schistosoma mansoni regulator of G protein signaling 0.0039 0.0106 0.0069
Schistosoma mansoni calpain-2 (C02 family) 0.0249 0.1018 0.0986
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0027 0.0055 0.0058
Echinococcus granulosus proteasome subunit beta type 7 0.0027 0.0055 0.0049
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.004 0.0111 0.0103
Plasmodium vivax vivapain-2 0.0689 0.2933 0.8278
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0156 0.0615 0.058
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0127 0.0491 0.0519
Trypanosoma brucei mitochondrial calcium uptake 1 0.0121 0.0465 0.1225
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0827 0.3532 0.6341
Leishmania major cysteine peptidase A (CPA) 0.0689 0.2933 0.8286
Loa Loa (eye worm) hypothetical protein 0.0216 0.0877 0.0927
Trypanosoma cruzi metacaspase, putative 0.015 0.059 0.1005
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0041 0.0118 0.0279
Schistosoma mansoni cathepsin F (C01 family) 0.0473 0.1993 0.1965
Brugia malayi Cytochrome P450 family protein 0.0041 0.0114 0.0106
Onchocerca volvulus 0.0689 0.2933 0.495
Echinococcus granulosus dual specificity protein kinase clk2 0.0074 0.0257 0.0252
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0689 0.2933 1
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0069 0.0238 0.0366
Plasmodium vivax metacaspase 1, putative 0.015 0.059 0.1547
Leishmania major hypothetical protein, conserved 0.0123 0.0472 0.1245
Echinococcus granulosus calmodulin 0.0121 0.0465 0.046
Echinococcus multilocularis mitogen activated protein kinase 3 0.0062 0.0207 0.0202
Entamoeba histolytica calmodulin, putative 0.0121 0.0465 0.1424
Trypanosoma brucei kinesin, putative 0.0578 0.2451 0.6908
Plasmodium vivax proteasome subunit beta type-4, putative 0.0027 0.0055 0.0008
Onchocerca volvulus 0.0689 0.2933 0.495
Loa Loa (eye worm) hypothetical protein 0.0039 0.0106 0.0112
Leishmania major calcineurin B subunit, putative 0.0121 0.0465 0.1225
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0027 0.0055 0.0008
Entamoeba histolytica protein kinase, putative 0.0579 0.2456 0.8343
Onchocerca volvulus 0.013 0.0502 0.0773
Entamoeba histolytica hypothetical protein 0.0156 0.0615 0.1944
Brugia malayi cathepsin Z-like cysteine proteinase 0.0156 0.0615 0.0636
Loa Loa (eye worm) hypothetical protein 0.039 0.163 0.1722
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0249 0.1018 0.2808
Brugia malayi proteasome subunit alpha type 1 0.0027 0.0055 0.0044
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0156 0.0615 0.2683
Echinococcus granulosus mitogen activated protein kinase 3 0.0062 0.0207 0.0202
Loa Loa (eye worm) hypothetical protein 0.0156 0.0615 0.0649
Schistosoma mansoni regulator of G protein signaling 0.0039 0.0106 0.0069
Trypanosoma cruzi Aph-1 protein, putative 0.005 0.0153 0.0211
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0689 0.2933 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0689 0.2933 1
Loa Loa (eye worm) hypothetical protein 0.0156 0.0615 0.0649
Trypanosoma brucei hypothetical protein 0.0249 0.1018 0.2808
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0689 0.2933 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0156 0.0615 0.1944
Plasmodium falciparum cysteine proteinase falcipain 3 0.0689 0.2933 1
Entamoeba histolytica cysteine proteinase, putative 0.0689 0.2933 1
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0121 0.0465 0.043
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0827 0.3532 0.6341
Echinococcus multilocularis beta adrenergic receptor kinase 0.004 0.0111 0.0105
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0192 0.0773 0.2493
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0118 0.0217
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0192 0.0773 0.1335
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0156 0.0615 0.1944
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0106 0.0176
Entamoeba histolytica cysteine protease, putative 0.0156 0.0615 0.1944
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0027 0.0055 0.0033
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.004 0.0111 0.0117
Echinococcus multilocularis calumenin 0.0123 0.0472 0.0466
Echinococcus granulosus calumenin 0.0123 0.0472 0.0466
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0156 0.0615 0.1944
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0027 0.0055 0.0049
Leishmania major proteasome alpha 1 subunit, putative 0.0027 0.0055 0.0053
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0062 0.0207 0.0309
Trypanosoma brucei centrin-3 0.0121 0.0465 0.1225
Trichomonas vaginalis calmodulin, putative 0.0121 0.0465 0.1424
Echinococcus multilocularis lamin dm0 0.0033 0.0079 0.0073
Loa Loa (eye worm) cytochrome P450 family protein 0.0041 0.0114 0.012
Onchocerca volvulus 0.0689 0.2933 0.495
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0035 0.0091 0.0055
Toxoplasma gondii proteasome subunit 0.0027 0.0055 0.0063
Brugia malayi intermediate filament protein 0.0033 0.0079 0.007
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0039 0.0106 0.0112
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0118 0.0217
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0207 0.0529
Leishmania major protein kinase, putative 0.0074 0.0257 0.0631
Leishmania major proteasome alpha 3 subunit, putative 0.0027 0.0055 0.0053
Leishmania major hypothetical protein, conserved 0.0249 0.1018 0.2808
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0249 0.1018 0.3346
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0249 0.1018 0.2808
Loa Loa (eye worm) hypothetical protein 0.0072 0.0252 0.0267
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0027 0.0055 0.0049
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0027 0.0055 0.0063
Brugia malayi Papain family cysteine protease containing protein 0.0156 0.0615 0.0636
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0156 0.0615 0.1944
Brugia malayi Proteasome A-type and B-type family protein 0.0027 0.0055 0.0044
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0249 0.1018 0.2808
Trypanosoma brucei Metacaspase-4 0.0041 0.0118 0.0232
Leishmania major centrin, putative 0.0121 0.0465 0.1225
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0249 0.1018 0.2808
Plasmodium falciparum serine repeat antigen 7 0.0156 0.0615 0.1944
Brugia malayi calpain 5 0.0249 0.1018 0.1063
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0784 0.3346 0.9468
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0192 0.0773 1
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0027 0.0055 0.0053
Toxoplasma gondii EFHC1, putative 0.0121 0.0465 0.1479
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0041 0.0118 0.0217
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0156 0.0615 0.058
Schistosoma mansoni microtubule-associated protein tau 0.0801 0.3419 0.3397
Brugia malayi Cathepsin L-like precursor 0.0689 0.2933 0.3089
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0069 0.0238 0.0636
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0784 0.3346 0.9468
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0827 0.3532 0.6341
Leishmania major calpain protease-like protein 0.0249 0.1018 0.2808
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0106 0.0176
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0062 0.0207 0.0488
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0027 0.0055 0.0058
Entamoeba histolytica cysteine protease, putative 0.0372 0.1554 0.521
Brugia malayi Proteasome subunit alpha type 1 0.0027 0.0055 0.0044
Onchocerca volvulus 0.0689 0.2933 0.495
Leishmania major cathepsin L-like protease 0.0689 0.2933 0.8286
Echinococcus multilocularis calpain family protein 1, d 0.1614 0.6952 0.695
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0827 0.3532 1
Trypanosoma cruzi metacaspase, putative 0.015 0.059 0.1005
Plasmodium vivax proteasome subunit beta type-3, putative 0.0027 0.0055 0.0008
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0039 0.0106 0.0069
Plasmodium vivax vivapain-2 0.0689 0.2933 0.8278
Giardia lamblia Proteasome subunit beta type 2 0.0066 0.0222 0.0803
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0249 0.1018 0.2808
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0027 0.0055 0.0063
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0689 0.2933 1
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0066 0.0222 0.0217
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0689 0.2933 1
Giardia lamblia Cathepsin L precursor 0.0156 0.0615 0.2683
Entamoeba histolytica cysteine proteinase 2 0.0372 0.1554 0.521
Onchocerca volvulus 0.0079 0.0283 0.0396
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0066 0.0222 0.0337
Echinococcus multilocularis regulator of G protein signaling 7 0.0039 0.0106 0.01
Echinococcus granulosus intermediate filament protein 0.0033 0.0079 0.0073
Echinococcus multilocularis calpain A 0.2315 1 1
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0027 0.0055 0.0053
Entamoeba histolytica cysteine protease, putative 0.0372 0.1554 0.521
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0027 0.0055 0.0053
Leishmania major proteasome beta 5 subunit, putative 0.0192 0.0773 0.2106
Echinococcus granulosus EF hand domain containing family member A2 0.0121 0.0465 0.046
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0249 0.1018 0.2808
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0054 0.0171 0.1823
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0689 0.2933 1
Schistosoma mansoni cathepsin B (C01 family) 0.0156 0.0615 0.058
Plasmodium falciparum calpain 0.0249 0.1018 0.3346
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0066 0.0222 0.0641
Entamoeba histolytica calmodulin, putative 0.0121 0.0465 0.1424
Entamoeba histolytica grainin, putative 0.0123 0.0472 0.1448
Loa Loa (eye worm) fibroinase 0.0689 0.2933 0.3098
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0074 0.0257 0.0631
Loa Loa (eye worm) cytochrome P450 family protein 0.0041 0.0114 0.012
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.0027 0.0055 0.0033
Entamoeba histolytica cysteine protease, putative 0.0372 0.1554 0.521
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0027 0.0055 0.0033
Schistosoma mansoni calpain-7 (C02 family) 0.0831 0.3547 0.3526
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0249 0.1018 0.2808
Trypanosoma cruzi kinesin, putative 0.0578 0.2451 0.4381
Leishmania major proteasome alpha 2 subunit, putative 0.0027 0.0055 0.0053
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0156 0.0615 0.1944
Leishmania major hypothetical protein, conserved 0.0121 0.0465 0.1225
Leishmania major proteasome beta 7 subunit, putative 0.0027 0.0055 0.0053
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0507 0.214 0.2113
Toxoplasma gondii cathepsin CPC1 0.0156 0.0615 0.1995
Entamoeba histolytica cysteine proteinase, putative 0.0372 0.1554 0.521
Entamoeba histolytica hypothetical protein 0.0039 0.0106 0.0176
Echinococcus granulosus proteasome subunit alpha type 6 0.0027 0.0055 0.0049
Echinococcus granulosus lamin dm0 0.0033 0.0079 0.0073
Echinococcus multilocularis calbindin 32 0.0123 0.0472 0.0466
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0249 0.1018 0.178
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0027 0.0055 0.0049
Brugia malayi cathepsin Z-like cysteine proteinase 0.0156 0.0615 0.0636
Entamoeba histolytica cysteine proteinase, putative 0.0689 0.2933 1
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0027 0.0055 0.0033
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.015 0.059 0.1912
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0249 0.1018 0.178
Trypanosoma cruzi calmodulin, putative 0.0121 0.0465 0.0777
Onchocerca volvulus 0.0689 0.2933 0.495
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0045 0.0131 0.0271
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0827 0.3532 1
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0122 0.047 0.0786
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0372 0.1554 0.521
Leishmania major metacaspase, putative 0.015 0.059 0.1584
Echinococcus granulosus lamin 0.0033 0.0079 0.0073
Brugia malayi A-kinase anchor protein 10, precursor 0.0039 0.0106 0.0098
Onchocerca volvulus 0.021 0.0849 0.137
Brugia malayi Intermediate filament tail domain containing protein 0.0033 0.0079 0.007
Plasmodium vivax serine/threonine kinase-1, putative 0.0074 0.0257 0.0589
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0111 0.0074
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2192 0.9466 0.947
Entamoeba histolytica cysteine protease, putative 0.0156 0.0615 0.1944
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0074 0.0257 0.0631
Brugia malayi 20S proteasome alpha5 subunit 0.0027 0.0055 0.0044
Trichomonas vaginalis calmodulin, putative 0.0121 0.0465 0.1424
Onchocerca volvulus 0.0689 0.2933 0.495
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0372 0.1554 0.4342
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0192 0.0773 0.0739
Entamoeba histolytica cysteine protease, putative 0.0372 0.1554 0.521
Echinococcus granulosus microtubule associated protein 2 0.0801 0.3419 0.3415
Toxoplasma gondii calmodulin CAM1 0.0123 0.0472 0.1502
Echinococcus granulosus mitogen activated protein kinase 0.0062 0.0207 0.0202
Entamoeba histolytica cysteine protease, putative 0.0156 0.0615 0.1944
Trypanosoma cruzi calmodulin, putative 0.0121 0.0465 0.0777
Echinococcus multilocularis calmodulin 0.0121 0.0465 0.046
Schistosoma mansoni calpain-7 (C02 family) 0.0831 0.3547 0.3526
Brugia malayi programmed cell death protein 6 0.0121 0.0465 0.0478
Plasmodium falciparum serine repeat antigen 8 0.0156 0.0615 0.1944
Trichomonas vaginalis calmodulin, putative 0.0121 0.0465 0.1424
Trichomonas vaginalis centrin, putative 0.0121 0.0465 0.1424
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0784 0.3346 0.9468
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0249 0.1018 0.178
Plasmodium falciparum serine repeat antigen 4 0.0156 0.0615 0.1944
Loa Loa (eye worm) hypothetical protein 0.0156 0.0615 0.0649
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0027 0.0055 0.0049
Echinococcus multilocularis cathepsin b 0.1291 0.5548 0.5546
Brugia malayi MAP kinase sur-1 0.0062 0.0207 0.0205
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.0027 0.0055 0.0053
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0372 0.1554 0.4342
Echinococcus granulosus proteasome subunit beta t family 0.0027 0.0055 0.0049
Entamoeba histolytica cysteine protease, putative 0.0156 0.0615 0.1944
Echinococcus granulosus regulator of G protein signaling 3 0.0039 0.0106 0.01
Echinococcus granulosus caspase 0.0041 0.0118 0.0112
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0027 0.0055 0.0008
Onchocerca volvulus Cathepsin L homolog 0.0689 0.2933 0.495
Leishmania major proteasome alpha 7 subunit, putative 0.0027 0.0055 0.0053
Schistosoma mansoni axis inhibition protein axin 0.0039 0.0106 0.0069
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0121 0.0465 0.1424
Trypanosoma brucei Aph-1 protein, putative 0.005 0.0153 0.0333
Echinococcus granulosus calpain A 0.0827 0.3532 0.3528
Schistosoma mansoni regulator of G protein signaling 0.0039 0.0106 0.0069
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0121 0.0465 0.046
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0249 0.1018 0.2808
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0121 0.0465 0.1424
Trypanosoma cruzi metacaspase 5, putative 0.015 0.059 0.1005
Loa Loa (eye worm) hypothetical protein 0.0156 0.0615 0.0649
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0027 0.0055 0.0033
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0689 0.2933 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0015
Loa Loa (eye worm) RGS-3 protein 0.0039 0.0106 0.0112
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0784 0.3346 0.9468
Toxoplasma gondii aldehyde dehydrogenase 0.0054 0.0171 0.0463
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0827 0.3532 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0041 0.0118 0.0217
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0118 0.0217
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0156 0.0615 0.1944
Brugia malayi PXA domain containing protein 0.0039 0.0106 0.0098
Echinococcus multilocularis neurocalcin 0.0121 0.0465 0.046
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0156 0.0615 0.1944
Loa Loa (eye worm) hypothetical protein 0.1365 0.5871 0.6203
Schistosoma mansoni caspase-7 (C14 family) 0.0041 0.0118 0.0081
Echinococcus granulosus cathepsin L cysteine protease 0.0372 0.1554 0.1549
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0689 0.2933 1
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0027 0.0055 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0156 0.0615 0.1944
Echinococcus granulosus cathepsin b 0.1291 0.5548 0.5546
Trypanosoma brucei Calpain-like protein 2 0.0249 0.1018 0.2808
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0689 0.2933 1
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0027 0.0055 0.0018
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0249 0.1018 0.2808
Echinococcus granulosus regulator of G protein signaling 7 0.0039 0.0106 0.01
Loa Loa (eye worm) hypothetical protein 0.0249 0.1018 0.1075
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0156 0.0615 0.1944
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0123 0.0472 0.0789
Trypanosoma brucei cysteine peptidase, putative 0.0249 0.1018 0.2808
Giardia lamblia Cathepsin L precursor 0.0156 0.0615 0.2683
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0041 0.0118 0.0112
Trypanosoma brucei hypothetical protein, conserved 0.0121 0.0465 0.1225
Onchocerca volvulus 0.0689 0.2933 0.495
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0041 0.0118 0.0217
Onchocerca volvulus Cathepsin L homolog 0.0156 0.0615 0.0966
Leishmania major hypothetical protein, unknown function 0.0249 0.1018 0.2808
Brugia malayi EF hand family protein 0.0121 0.0465 0.0478
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0827 0.3532 0.6341
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0045 0.0131 0.0126
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0027 0.0055 0.0058
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0689 0.2933 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0041 0.0118 0.0217
Brugia malayi proteasome subunit alpha type 4 0.0027 0.0055 0.0044
Brugia malayi proteasome subunit beta type 3 0.0027 0.0055 0.0044
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0013 0.0014
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0156 0.0615 0.1616
Toxoplasma gondii proteasome subunit alpha type, putative 0.0027 0.0055 0.0063
Giardia lamblia Cathepsin B precursor 0.0507 0.214 1
Onchocerca volvulus Notchless protein homolog 0.0027 0.0055 0.0005
Loa Loa (eye worm) hypothetical protein 0.1614 0.6952 0.7344
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0131 0.0266
Leishmania major cathepsin L-like protease 0.0784 0.3346 0.9468
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0207 0.0171
Echinococcus granulosus cathepsin L 0.0156 0.0615 0.0609
Brugia malayi cathepsin L precursor 0.0156 0.0615 0.0636
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0156 0.0615 0.058
Schistosoma mansoni cathepsin C 0.0156 0.0615 0.058
Schistosoma mansoni hypothetical protein 0.0249 0.1018 0.0986
Entamoeba histolytica hypothetical protein 0.0039 0.0106 0.0176
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0069 0.0238 0.0696
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0027 0.0055 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0118 0.0217
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0156 0.0615 0.1616
Echinococcus granulosus neuronal calcium sensor 0.0121 0.0465 0.046
Echinococcus multilocularis dual specificity protein kinase clk2 0.0074 0.0257 0.0252
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0207 0.0529
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0106 0.0176
Echinococcus granulosus expressed protein 0.0754 0.3215 0.3211
Entamoeba histolytica cysteine protease, putative 0.0156 0.0615 0.1944
Brugia malayi Papain family cysteine protease containing protein 0.0372 0.1554 0.163
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0027 0.0055 0.0053
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0054 0.0171 0.0165
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0121 0.0465 0.0777
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0122 0.047 0.12
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0249 0.1018 0.2808
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.0027 0.0055 0.0249
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0027 0.0055 0.0033
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0192 0.0773 0.2106
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0122 0.047 0.0786
Plasmodium vivax unspecified product 0.0156 0.0615 0.1616
Brugia malayi Cathepsin L-like precursor 0.0689 0.2933 0.3089
Plasmodium vivax serine-repeat antigen (SERA) 0.0156 0.0615 0.1616
Schistosoma mansoni cathepsin F (C01 family) 0.0689 0.2933 0.2909
Giardia lamblia Cathepsin B precursor 0.0156 0.0615 0.2683
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0156 0.0615 0.2683
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0784 0.3346 0.9468
Plasmodium falciparum cysteine proteinase falcipain 1 0.0372 0.1554 0.521
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0827 0.3532 0.6341
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0689 0.2933 1
Brugia malayi cathepsin F-like cysteine proteinase 0.0216 0.0877 0.0914
Echinococcus multilocularis survival motor neuron protein 1 0.039 0.163 0.1626
Echinococcus granulosus survival motor neuron protein 1 0.039 0.163 0.1626
Trypanosoma brucei centrin, putative 0.0121 0.0465 0.1225
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0027 0.0055 0.0049
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0027 0.0055 0.0033
Plasmodium vivax hypothetical protein, conserved 0.0123 0.0472 0.1206
Schistosoma mansoni regulator of G protein signaling 0.0039 0.0106 0.0069
Echinococcus granulosus subfamily T1A non peptidase ue 0.0027 0.0055 0.0049
Loa Loa (eye worm) hypothetical protein 0.0039 0.0106 0.0112
Loa Loa (eye worm) cathepsin B 0.0507 0.214 0.2261
Trypanosoma brucei calpain-like protein, putative 0.0827 0.3532 1
Brugia malayi proteasome subunit alpha type 6 0.0027 0.0055 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0249 0.1018 0.3346
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0027 0.0055 0.0018
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0156 0.0615 0.0649
Echinococcus granulosus cytochrome P450 2K1 0.0023 0.0037 0.0031
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0249 0.1018 0.2808
Trypanosoma brucei protein I/6 0.0121 0.0465 0.1225
Loa Loa (eye worm) hypothetical protein 0.0026 0.0052 0.0055
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0027 0.0055 0.0033
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0027 0.0055 0.0018
Giardia lamblia Kinase, CMGC CLK 0.0074 0.0257 0.0969
Entamoeba histolytica cysteine protease, putative 0.0372 0.1554 0.521
Brugia malayi Cathepsin L-like precursor 0.0689 0.2933 0.3089
Toxoplasma gondii proteasome subunit alpha1, putative 0.0027 0.0055 0.0063
Trypanosoma brucei metacaspase 0.0041 0.0118 0.0232
Entamoeba histolytica cysteine protease, putative 0.0372 0.1554 0.521
Plasmodium falciparum serine repeat antigen 9 0.0156 0.0615 0.1944
Brugia malayi Regulator of G protein signaling domain containing protein 0.0039 0.0106 0.0098
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0026 0.0052 0.0016
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0372 0.1554 0.1524
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0249 0.1018 0.2808
Brugia malayi Cytochrome P450 family protein 0.0061 0.0204 0.0202
Brugia malayi proteasome subunit alpha type 2 0.0027 0.0055 0.0044
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0027 0.0055 0.0049
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0027 0.0055 0.0018
Entamoeba histolytica calcium binding family protein 0.0121 0.0465 0.1424
Echinococcus granulosus calpain 0.0827 0.3532 0.3528
Trypanosoma cruzi cysteine proteinase, putative 0.0372 0.1554 0.2753
Brugia malayi cytochrome P450 0.0023 0.0037 0.0025
Toxoplasma gondii peptidase, T1 family protein 0.0027 0.0055 0.0063
Leishmania major cathepsin L-like protease 0.0689 0.2933 0.8286
Brugia malayi Proteasome A-type and B-type family protein 0.0027 0.0055 0.0044
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0027 0.0055 0.0018
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0192 0.0773 0.1335
Brugia malayi gamma-secretase subunit aph-1 0.0127 0.0491 0.0506
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0027 0.0055 0.0058
Brugia malayi Proteasome subunit alpha type 7-1 0.0027 0.0055 0.0044
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0027 0.0055 0.0049
Trypanosoma brucei proteasome alpha 7 subunit 0.0027 0.0055 0.0053
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0062 0.0207 0.0219
Trypanosoma cruzi cysteine proteinase, putative 0.0372 0.1554 0.2753
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0156 0.0615 0.058
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0249 0.1018 0.178
Brugia malayi Cathepsin L-like precursor 0.0473 0.1993 0.2094
Entamoeba histolytica hypothetical protein 0.0039 0.0106 0.0176
Echinococcus multilocularis 0.0072 0.0252 0.0247
Brugia malayi Pre-SET motif family protein 0.0026 0.0052 0.0041
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0507 0.214 0.7247
Brugia malayi regulator of G-protein signaling rgs-7 0.0039 0.0106 0.0098
Echinococcus multilocularis caspase 0.0041 0.0118 0.0112
Echinococcus multilocularis Regulator of G protein signaling 20 0.0039 0.0106 0.01
Trypanosoma cruzi cysteine peptidase, putative 0.0784 0.3346 0.6004
Echinococcus granulosus neurocalcin 0.0121 0.0465 0.046
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0784 0.3346 0.9468
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0041 0.0118 0.0112
Echinococcus multilocularis axis inhibition protein axin 0.0039 0.0106 0.01
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0156 0.0615 0.058
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0039 0.0106 0.0176
Echinococcus granulosus histone lysine methyltransferase setb 0.0026 0.0052 0.0046
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0123 0.0472 0.0437
Giardia lamblia Hypothetical protein 0.0156 0.0615 0.2683
Loa Loa (eye worm) ctsf protein 0.0689 0.2933 0.3098
Trypanosoma cruzi metacaspase 5, putative 0.015 0.059 0.1005
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0156 0.0615 0.1616
Giardia lamblia Cysteine protease 0.0156 0.0615 0.2683
Echinococcus multilocularis lamin 0.0033 0.0079 0.0073
Leishmania major proteasome alpha 1 subunit, putative 0.0027 0.0055 0.0053
Trichomonas vaginalis calmodulin, putative 0.0121 0.0465 0.1424
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0027 0.0055 0.0058
Trypanosoma brucei calpain-like protein, putative 0.0827 0.3532 1
Trypanosoma cruzi cysteine peptidase, putative 0.0784 0.3346 0.6004
Trichomonas vaginalis calpain, putative 0.0249 0.1018 0.3346
Brugia malayi Papain family cysteine protease containing protein 0.0372 0.1554 0.163
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0131 0.0266
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0122 0.047 0.1239
Schistosoma mansoni hypothetical protein 0.0079 0.0283 0.0247
Loa Loa (eye worm) cytochrome P450 0.0023 0.0037 0.0039
Trypanosoma cruzi cysteine peptidase, putative 0.0784 0.3346 0.6004
Brugia malayi Cathepsin L-like precursor 0.0216 0.0877 0.0914
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0121 0.0465 0.046
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0784 0.3346 0.9468
Echinococcus multilocularis cathepsin L 0.0372 0.1554 0.1549
Toxoplasma gondii hypothetical protein 0.0249 0.1018 0.3388
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0689 0.2933 1
Entamoeba histolytica hypothetical protein, conserved 0.0123 0.0472 0.1448
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0069 0.0238 0.0233
Trichomonas vaginalis centrin, putative 0.0121 0.0465 0.1424
Loa Loa (eye worm) hypothetical protein 0.0045 0.0131 0.0139
Leishmania major proteasome beta-1 subunit, putative 0.0027 0.0055 0.0053
Echinococcus multilocularis axis inhibition protein axin 0.0039 0.0106 0.01
Onchocerca volvulus Cathepsin L homolog 0.0689 0.2933 0.495
Echinococcus multilocularis calpain 7 (C02 family) 0.0827 0.3532 0.3528
Trichomonas vaginalis calcineurin B subunit, putative 0.0123 0.0472 0.1448
Loa Loa (eye worm) intermediate filament protein 0.0033 0.0079 0.0083
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0372 0.1554 0.1524
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0249 0.1018 0.178
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0027 0.0055 0.0008
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0827 0.3532 1
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0156 0.0615 0.1944
Loa Loa (eye worm) calpain family protein 1 0.2192 0.9466 1
Giardia lamblia Cysteine protease 0.0156 0.0615 0.2683
Echinococcus multilocularis calcium uptake protein 1 0.0123 0.0472 0.0466
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0568 0.2406 0.4299
Echinococcus multilocularis hypothetical protein 0.0827 0.3532 0.3528
Leishmania major cathepsin L-like protease 0.0689 0.2933 0.8286
Plasmodium vivax calpain, putative 0.0827 0.3532 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0003
Trypanosoma cruzi cruzipain precursor, putative 0.0784 0.3346 0.6004
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0372 0.1554 0.1524
Entamoeba histolytica cysteine protease, putative 0.0372 0.1554 0.521
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1291 0.5548 0.5536
Leishmania major protein kinase, putative 0.0122 0.047 0.1239
Trypanosoma brucei Calpain-like protein 1.1 0.0249 0.1018 0.2808
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0027 0.0055 0.0033
Trypanosoma cruzi cytochrome P450, putative 0.0041 0.0114 0.014
Toxoplasma gondii heat shock protein hslv, putative 0.0027 0.0055 0.0063
Trichomonas vaginalis calcium binding protein, putative 0.0121 0.0465 0.1424
Loa Loa (eye worm) EF hand family protein 0.0121 0.0465 0.0491
Toxoplasma gondii cathepsin B 0.0507 0.214 0.7265
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0689 0.2933 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0006
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0249 0.1018 0.178
Echinococcus granulosus Proteasome subunit alpha beta 0.0027 0.0055 0.0049
Loa Loa (eye worm) calpain 0.0827 0.3532 0.3731
Trypanosoma cruzi caltractin, putative 0.0121 0.0465 0.0777
Leishmania major calmodulin, putative 0.0121 0.0465 0.1225
Trichomonas vaginalis calpain, putative 0.0249 0.1018 0.3346
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0074 0.0257 0.04
Echinococcus granulosus cathepsin l1 0.0473 0.1993 0.1988
Giardia lamblia Cathepsin B precursor 0.0156 0.0615 0.2683
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0027 0.0055 0.0033
Plasmodium vivax vivapain-3 0.0372 0.1554 0.4317
Schistosoma mansoni caspase-3 (C14 family) 0.0041 0.0118 0.0081
Leishmania major cathepsin L-like protease 0.0784 0.3346 0.9468
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0027 0.0055 0.0018
Trypanosoma cruzi kinesin, putative 0.0578 0.2451 0.4381
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0079 0.0283 0.0285
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0121 0.0465 0.0777
Echinococcus granulosus proteasome prosome macropain 0.0192 0.0773 0.0767
Brugia malayi Calmodulin-like protein 0.0121 0.0465 0.0478
Plasmodium vivax centrin-1, putative 0.0121 0.0465 0.1186
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0027 0.0055 0.0008
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0027 0.0055 0.0018
Toxoplasma gondii cathepsin CPL 0.0689 0.2933 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0156 0.0615 0.1944
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0027 0.0055 0.0058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0156 0.0615 0.1944
Leishmania major proteasome alpha 7 subunit, putative 0.0027 0.0055 0.0053
Brugia malayi Papain family cysteine protease containing protein 0.0156 0.0615 0.0636
Schistosoma mansoni hypothetical protein 0.0121 0.0465 0.043
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0121 0.0465 0.1424
Loa Loa (eye worm) follicle stimulating hormone receptor 0.028 0.1153 0.1218
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0041 0.0118 0.0081
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.0027 0.0055 0.5
Schistosoma mansoni ef hand domain family member A2 0.0121 0.0465 0.043
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0156 0.0615 0.058
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0192 0.0773 1
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0249 0.1018 0.178
Echinococcus multilocularis 0.0023 0.0037 0.0031
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0156 0.0615 0.1944
Echinococcus multilocularis neuronal calcium sensor 0.0121 0.0465 0.046
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0027 0.0055 0.0018
Trichomonas vaginalis hypothetical protein 0.0249 0.1018 0.3346
Toxoplasma gondii calcium-dependent protein kinase 0.0124 0.0477 0.1519
Schistosoma mansoni serine/threonine protein kinase 0.0074 0.0257 0.0221
Trichomonas vaginalis calcium binding proteins, putative 0.0121 0.0465 0.1424
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0249 0.1018 0.3346
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0027 0.0055 0.0033
Onchocerca volvulus Cathepsin F homolog 0.0689 0.2933 0.495
Loa Loa (eye worm) hypothetical protein 0.0473 0.1993 0.2105
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0041 0.0118 0.0217
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0249 0.1018 0.2808
Schistosoma mansoni neuronal calcium sensor 0.0121 0.0465 0.043
Plasmodium vivax unspecified product 0.0216 0.0877 0.2371
Echinococcus multilocularis proteasome subunit alpha type 2 0.0027 0.0055 0.0049
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0066 0.0222 0.0582
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0045 0.0131 0.0172
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0066 0.0222 0.0187
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0062 0.0207 0.0309
Echinococcus multilocularis proteasome subunit beta type 7 0.0027 0.0055 0.0049
Trypanosoma cruzi centrin-3 0.0121 0.0465 0.0777
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0184 0.0738 0.0779
Schistosoma mansoni caspase-7 (C14 family) 0.0041 0.0118 0.0081
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0249 0.1018 0.178
Leishmania major calmodulin-like protein 0.0121 0.0465 0.1225
Trichomonas vaginalis calcium binding protein, putative 0.0121 0.0465 0.1424
Giardia lamblia Cathepsin L-like protease 0.0156 0.0615 0.2683
Schistosoma mansoni mitochondrial solute carrier 0.0121 0.0465 0.043
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0827 0.3532 0.6341
Leishmania major cathepsin L-like protease 0.0689 0.2933 0.8286
Echinococcus multilocularis cathepsin b 0.1291 0.5548 0.5546
Plasmodium vivax proteasome subunit beta type-6, putative 0.0027 0.0055 0.0008
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0111 0.0074
Brugia malayi Protein kinase domain containing protein 0.0074 0.0257 0.0258
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0026 0.0052 0.0046
Echinococcus granulosus calbindin 32 0.0123 0.0472 0.0466
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0249 0.1018 0.2808
Echinococcus granulosus cathepsin l cysteine peptidase 0.0689 0.2933 0.2929
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0066 0.0222 0.0582
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0156 0.0615 0.1944
Echinococcus multilocularis musashi 0.0033 0.0079 0.0073
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0249 0.1018 0.178
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0156 0.0615 0.1944
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0045 0.0131 0.0126
Trypanosoma cruzi cruzipain precursor, putative 0.0216 0.0877 0.1525
Trypanosoma brucei cysteine peptidase C (CPC) 0.0507 0.214 0.602
Trypanosoma brucei Component of motile flagella 41 0.0121 0.0465 0.1225
Loa Loa (eye worm) hypothetical protein 0.0034 0.0085 0.009
Brugia malayi cathepsin L-like precursor 0.0473 0.1993 0.2094
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0045 0.0131 0.0095
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0156 0.0615 0.1944
Trypanosoma brucei calpain, putative 0.0249 0.1018 0.2808
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0062 0.0207 0.0309
Entamoeba histolytica cysteine protease, putative 0.0372 0.1554 0.521
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0249 0.1018 0.2808
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0027 0.0055 0.0053
Loa Loa (eye worm) hypothetical protein 0.1944 0.8385 0.8858
Mycobacterium ulcerans aldehyde dehydrogenase 0.0054 0.0171 0.1823
Echinococcus granulosus regulator of G protein signaling 7 0.0039 0.0106 0.01
Trichomonas vaginalis myosin light chain 1, putative 0.0121 0.0465 0.1424
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0027 0.0055 0.0033
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0216 0.0877 0.0914
Echinococcus granulosus cathepsin b 0.1291 0.5548 0.5546
Entamoeba histolytica cysteine protease, putative 0.0372 0.1554 0.521
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0156 0.0615 0.1616
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0207 0.0529
Trypanosoma brucei caltractin, putative 0.0121 0.0465 0.1225
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0156 0.0615 0.1616
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0689 0.2933 0.3098
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0027 0.0055 0.0049
Plasmodium falciparum serine repeat antigen 2 0.0156 0.0615 0.1944
Schistosoma mansoni calmodulin related calcium binding protein 0.0121 0.0465 0.043
Trypanosoma cruzi centrin, putative 0.0121 0.0465 0.0777
Echinococcus multilocularis microtubule associated protein 2 0.0801 0.3419 0.3415
Loa Loa (eye worm) proteasome subunit beta type 1 0.0069 0.0238 0.0252
Schistosoma mansoni centrin-related 0.0121 0.0465 0.043
Entamoeba histolytica grainin 2 0.0121 0.0465 0.1424
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0827 0.3532 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0041 0.0118 0.0217
Trichomonas vaginalis calmodulin, putative 0.0121 0.0465 0.1424
Schistosoma mansoni aldehyde dehydrogenase 0.0054 0.0171 0.0135
Brugia malayi Cytochrome P450 family protein 0.0023 0.0037 0.0025
Trypanosoma brucei proteasome beta 7 subunit 0.0027 0.0055 0.0053
Mycobacterium ulcerans proteasome PrcB 0.0192 0.0773 1
Giardia lamblia Cathepsin L precursor 0.0156 0.0615 0.2683
Trichomonas vaginalis set domain proteins, putative 0.021 0.0848 0.2756
Giardia lamblia Cysteine protease 0.0156 0.0615 0.2683
Echinococcus multilocularis calmodulin 0.0121 0.0465 0.046
Toxoplasma gondii troponin c, isotype gamma, putative 0.0121 0.0465 0.1479
Plasmodium vivax proteasome subunit beta type-5, putative 0.0192 0.0773 0.207
Loa Loa (eye worm) hypothetical protein 0.0039 0.0106 0.0112
Onchocerca volvulus 0.0121 0.0465 0.0709
Loa Loa (eye worm) proteasome subunit beta type 2 0.0066 0.0222 0.0235
Echinococcus granulosus cathepsin L cysteine proteinase 0.0689 0.2933 0.2929
Brugia malayi proteasome subunit alpha type 3 0.0027 0.0055 0.0044
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0041 0.0118 0.0217
Brugia malayi calcium-binding protein 0.0121 0.0465 0.0478
Loa Loa (eye worm) AStacin protease 0.0022 0.0034 0.0035
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0249 0.1018 0.2808
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0041 0.0118 0.0279
Echinococcus granulosus proteasome subunit alpha type 2 0.0027 0.0055 0.0049
Brugia malayi calpain 7 0.0827 0.3532 0.3722
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0249 0.1018 0.178
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0027 0.0055 0.0018
Toxoplasma gondii preprocathepsin c precursor, putative 0.0156 0.0615 0.1995
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0249 0.1018 0.2808
Trypanosoma brucei metacaspase 5, putative 0.015 0.059 0.1584
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0045 0.0131 0.0126
Plasmodium vivax proteasome subunit beta type-1, putative 0.0069 0.0238 0.0535
Echinococcus granulosus caspase 2 0.0041 0.0118 0.0112
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0372 0.1554 0.2753
Echinococcus multilocularis mitogen activated protein kinase 0.0062 0.0207 0.0202
Entamoeba histolytica cysteine protease, putative 0.0156 0.0615 0.1944
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0249 0.1018 0.2808
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0027 0.0055 0.0063
Trypanosoma cruzi I/6 autoantigen, putative 0.0121 0.0465 0.0777
Entamoeba histolytica cysteine protease, putative 0.0372 0.1554 0.521
Giardia lamblia Hypothetical protein 0.0123 0.0472 0.1998
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0026 0.0052 0.0016
Plasmodium falciparum metacaspase 1 0.015 0.059 0.1861
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0689 0.2933 1
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0111 0.0074
Brugia malayi Papain family cysteine protease containing protein 0.0689 0.2933 0.3089
Trichomonas vaginalis conserved hypothetical protein 0.0121 0.0465 0.1424
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0054 0.0171 0.0384
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0827 0.3532 0.6341
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0473 0.1993 0.6734
Loa Loa (eye worm) hypothetical protein 0.0041 0.0118 0.0124
Entamoeba histolytica cysteine proteinase, putative 0.0372 0.1554 0.521
Echinococcus granulosus hypothetical protein 0.0072 0.0252 0.0247
Leishmania major calpain family cysteine protease-like protein 0.0249 0.1018 0.2808
Schistosoma mansoni calmodulin 0.0121 0.0465 0.043
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0027 0.0055 0.0053
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0027 0.0055 0.0053
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0121 0.0465 0.1424
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0156 0.0615 0.1944
Loa Loa (eye worm) programmed cell death protein 6 0.0123 0.0472 0.0498
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0156 0.0615 0.0636
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0027 0.0055 0.0008
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0027 0.0055 0.0018
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0069 0.0238 0.0577
Echinococcus granulosus tumor protein p63 0.029 0.1199 0.1194
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0121 0.0465 0.0777
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0507 0.214 0.602
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0156 0.0615 0.2683
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0069 0.0238 0.0636
Loa Loa (eye worm) PAS-3 protein 0.0027 0.0055 0.0058
Trichomonas vaginalis calmodulin, putative 0.0121 0.0465 0.1424
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.2314 0.9993 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0249 0.1018 0.178
Trichomonas vaginalis calmodulin, putative 0.0123 0.0472 0.1448
Loa Loa (eye worm) hypothetical protein 0.0039 0.0106 0.0112
Brugia malayi Proteasome A-type and B-type family protein 0.0192 0.0773 0.0803
Loa Loa (eye worm) hypothetical protein 0.013 0.0502 0.053
Schistosoma mansoni serine/threonine protein kinase 0.0074 0.0257 0.0221
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0689 0.2933 0.2929
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0035 0.0091 0.0096
Brugia malayi hypothetical protein 0.0039 0.0106 0.0098
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0027 0.0055 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0689 0.2933 1
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0074 0.0257 0.0272
Schistosoma mansoni neuronal calcium sensor 0.0121 0.0465 0.043
Giardia lamblia Proteasome subunit beta type 1 0.0069 0.0238 0.0878
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1291 0.5548 0.5536
Brugia malayi PXA domain containing protein 0.0039 0.0106 0.0098
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0027 0.0055 0.0033
Schistosoma mansoni z-protein (S1r protein) 0.0039 0.0106 0.0069
Toxoplasma gondii proteasome subunit beta type, putative 0.0192 0.0773 0.2541
Brugia malayi hypothetical protein 0.013 0.0502 0.0517
Giardia lamblia Cathepsin B precursor 0.0507 0.214 1
Schistosoma mansoni cellular tumor antigen P53 0.0043 0.0122 0.0086
Echinococcus granulosus Regulator of G protein signaling 20 0.0039 0.0106 0.01
Leishmania major proteasome beta 3 subunit, putative 0.0027 0.0055 0.0053
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0249 0.1018 0.178
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1291 0.5548 0.5536
Echinococcus granulosus cathepsin l1 0.0689 0.2933 0.2929
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0027 0.0055 0.0033
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0039 0.0106 0.01
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0249 0.1018 0.178
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0027 0.0055 0.0063
Schistosoma mansoni cathepsin F (C01 family) 0.0689 0.2933 0.2909
Giardia lamblia Cathepsin L-like protease 0.0156 0.0615 0.2683
Plasmodium vivax unspecified product 0.0372 0.1554 0.4317
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0062 0.0207 0.0488
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0069 0.0238 0.0636
Trypanosoma brucei Calpain-like protein 1.2 0.0249 0.1018 0.2808
Echinococcus granulosus gamma secretase subunit aph 1 0.0127 0.0491 0.0486
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0249 0.1018 0.2808
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0027 0.0055 0.0033
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0192 0.0773 0.2493
Toxoplasma gondii centrin 0.0121 0.0465 0.1479
Trypanosoma brucei cytochrome P450, putative 0.0041 0.0114 0.022
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0026 0.0052 0.0053
Brugia malayi Regulator of G protein signaling domain containing protein 0.0039 0.0106 0.0098
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0249 0.1018 0.178
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0689 0.2933 1
Echinococcus multilocularis programmed cell death protein 0.0121 0.0465 0.046
Trichomonas vaginalis calcium binding protein, putative 0.0121 0.0465 0.1424
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0689 0.2933 0.3098
Trypanosoma brucei calpain-like protein, putative 0.0827 0.3532 1
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0156 0.0615 0.1616
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0041 0.0118 0.0217
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0689 0.2933 1
Entamoeba histolytica cysteine proteinase 1, putative 0.0372 0.1554 0.521
Brugia malayi calpain family protein 1 0.2192 0.9466 1
Echinococcus multilocularis ubiquitin specific protease 41 0.0045 0.0131 0.0126
Leishmania major centrin, putative,caltractin, putative 0.0121 0.0465 0.1225
Mycobacterium ulcerans aldehyde dehydrogenase 0.0054 0.0171 0.1823
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0027 0.0055 0.0053
Echinococcus granulosus centrin 2 0.0121 0.0465 0.046
Loa Loa (eye worm) hypothetical protein 0.0216 0.0877 0.0927
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0249 0.1018 0.3346
Leishmania major proteasome beta 2 subunit, putative 0.0027 0.0055 0.0053
Trichomonas vaginalis calmodulin, putative 0.0121 0.0465 0.1424
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0216 0.0877 0.0927
Loa Loa (eye worm) calpain 5 0.0578 0.2451 0.2589
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0473 0.1993 0.6734
Giardia lamblia Cathepsin B precursor 0.0507 0.214 1
Giardia lamblia Kinase, CMGC MAPK 0.0062 0.0207 0.073
Trypanosoma brucei Calpain-like protein CALP1.3 0.0249 0.1018 0.2808
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0372 0.1554 0.521
Brugia malayi cathepsin L-like cysteine proteinase 0.0156 0.0615 0.0636
Trichomonas vaginalis calmodulin, putative 0.0121 0.0465 0.1424
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0027 0.0055 0.0018
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0027 0.0055 0.0049
Loa Loa (eye worm) CYP4Cod1 0.0041 0.0114 0.012
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0062 0.0207 0.0589
Trypanosoma cruzi major cysteine proteinase, putative 0.0251 0.1028 0.1798
Schistosoma mansoni cathepsin S (C01 family) 0.0156 0.0615 0.058
Toxoplasma gondii cathepsin CPC2 0.0156 0.0615 0.1995
Trichomonas vaginalis conserved hypothetical protein 0.0156 0.0615 0.1944
Schistosoma mansoni calpain (C02 family) 0.0827 0.3532 0.351
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0027 0.0055 0.0033
Echinococcus multilocularis regulator of G protein signaling 0.0039 0.0106 0.01
Brugia malayi proteasome subunit beta type 2 0.0066 0.0222 0.0221
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0045 0.0131 0.0271
Echinococcus multilocularis cysteine protease 0.0689 0.2933 0.2929
Loa Loa (eye worm) hypothetical protein 0.0216 0.0877 0.0927
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0156 0.0615 0.058
Trichomonas vaginalis calcium binding protein, putative 0.0121 0.0465 0.1424
Trypanosoma cruzi cysteine peptidase, putative 0.0216 0.0877 0.1525
Onchocerca volvulus 0.0121 0.0465 0.0709
Brugia malayi calpain family protein 1 0.2192 0.9466 1
Trypanosoma cruzi cysteine protease, putative 0.0372 0.1554 0.2753
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0689 0.2933 1
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0027 0.0055 0.0053
Echinococcus multilocularis proteasome subunit alpha type 6 0.0027 0.0055 0.0049
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0156 0.0615 0.1616
Trypanosoma brucei calpain-like protein, putative 0.0827 0.3532 1
Echinococcus multilocularis Tolloid protein 1 0.0035 0.0091 0.0086
Onchocerca volvulus 0.0033 0.0079 0.0046
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0074 0.0257 0.04
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0027 0.0055 0.0033
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0689 0.2933 1
Trypanosoma cruzi cysteine peptidase, putative 0.0372 0.1554 0.2753
Echinococcus multilocularis regulator of G protein signaling 3 0.0039 0.0106 0.01
Plasmodium vivax proteasome subunit beta type-7, putative 0.0027 0.0055 0.0008
Brugia malayi hypothetical protein 0.0039 0.0106 0.0098
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0066 0.0222 0.0217
Schistosoma mansoni lamin 0.0033 0.0079 0.0042
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0156 0.0615 0.058
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0027 0.0055 0.0018
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0066 0.0222 0.0187
Loa Loa (eye worm) hypothetical protein 0.0473 0.1993 0.2105
Entamoeba histolytica cysteine proteinase, putative 0.0372 0.1554 0.521
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0689 0.2933 1
Schistosoma mansoni reticulocalbin 0.0123 0.0472 0.0437
Loa Loa (eye worm) proteasome subunit beta type 3 0.0027 0.0055 0.0058
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0156 0.0615 0.1616
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0192 0.0773 0.0816
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0027 0.0055 0.0058
Brugia malayi cathepsin F-like cysteine proteinase 0.0156 0.0615 0.0636
Giardia lamblia Cathepsin B precursor 0.0156 0.0615 0.2683
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0027 0.0055 0.0008
Plasmodium vivax proteasome subunit beta type-2, putative 0.0066 0.0222 0.0489
Loa Loa (eye worm) PXA domain-containing protein 0.0039 0.0106 0.0112
Trypanosoma brucei antigen, putative 0.0827 0.3532 1
Brugia malayi calpain D 0.0249 0.1018 0.1063
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0027 0.0055 0.0053
Echinococcus multilocularis regulator of G protein signaling 3 0.0039 0.0106 0.01
Plasmodium vivax vivapain-1 0.0372 0.1554 0.4317
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0069 0.0238 0.0202
Giardia lamblia Hypothetical protein 0.0156 0.0615 0.2683
Toxoplasma gondii centrin, putative 0.0121 0.0465 0.1479
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.2314 0.9993 0.9993
Leishmania major i/6 autoantigen-like protein 0.0121 0.0465 0.1225
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0062 0.0207 0.0488
Schistosoma mansoni regulator of G protein signaling 0.0039 0.0106 0.0069
Trypanosoma cruzi 20S proteasome subunit 0.0066 0.0222 0.0337
Brugia malayi Cathepsin L-like cysteine proteinase 0.0473 0.1993 0.2094
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0689 0.2933 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0827 0.3532 0.6341
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0074 0.0257 0.0761
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0249 0.1018 0.2808
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0156 0.0615 0.1944
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1291 0.5548 0.5536
Brugia malayi Cathepsin L-like precursor 0.0473 0.1993 0.2094
Echinococcus multilocularis calpain 0.0827 0.3532 0.3528
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0069 0.0238 0.0366
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0689 0.2933 1
Schistosoma mansoni survival motor neuron protein 0.0079 0.0283 0.0247
Trichomonas vaginalis calpain, putative 0.0249 0.1018 0.3346
Echinococcus granulosus axis inhibition protein axin 0.0039 0.0106 0.01
Trypanosoma brucei calpain, putative 0.0249 0.1018 0.2808
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0027 0.0055 0.0053
Loa Loa (eye worm) hypothetical protein 0.0121 0.0465 0.0491
Echinococcus multilocularis expressed protein 0.0754 0.3215 0.3211
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0028 0.006 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0118 0.0217
Brugia malayi calpain 5 0.0578 0.2451 0.2579
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0156 0.0615 0.2683
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0249 0.1018 0.3346
Plasmodium falciparum metacaspase-like protein 0.0041 0.0118 0.0217
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0249 0.1018 0.178
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0027 0.0055 0.0018
Leishmania major protein kinase, putative 0.0074 0.0257 0.0631
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0131 0.0266
Entamoeba histolytica cysteine proteinase, putative 0.0473 0.1993 0.6734
Trypanosoma cruzi metacaspase, putative 0.015 0.059 0.1005
Trypanosoma cruzi calmodulin, putative 0.0121 0.0465 0.0777
Giardia lamblia Cathepsin B precursor 0.0156 0.0615 0.2683
Giardia lamblia Cysteine protease 0.0156 0.0615 0.2683
Schistosoma mansoni gamma-secretase subunit aph-1 0.0127 0.0491 0.0456
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0045 0.0131 0.0095
Echinococcus multilocularis proteasome (prosome, macropain) 0.0192 0.0773 0.0767
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0027 0.0055 0.0063
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0027 0.0055 0.0033
Echinococcus granulosus beta-adrenergic receptor kinase 0.004 0.0111 0.0105
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0045 0.0131 0.0266
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0689 0.2933 1
Loa Loa (eye worm) hypothetical protein 0.1291 0.5548 0.5862
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0027 0.0055 0.0049
Schistosoma mansoni calpain C (C02 family) 0.0827 0.3532 0.351
Echinococcus granulosus proteasome subunit beta type 6 0.0027 0.0055 0.0049
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0027 0.0055 0.0049
Schistosoma mansoni neuronal calcium sensor 0.0121 0.0465 0.043
Trypanosoma cruzi major cysteine proteinase, putative 0.0156 0.0615 0.1048
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0156 0.0615 0.1944
Echinococcus multilocularis cathepsin L cysteine protease 0.0689 0.2933 0.2929
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0249 0.1018 0.2808
Plasmodium falciparum serine repeat antigen 6 0.0156 0.0615 0.1944
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0027 0.0055 0.0249
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0689 0.2933 0.2929
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0027 0.0055 0.0053
Loa Loa (eye worm) calpain D 0.0249 0.1018 0.1075
Plasmodium falciparum centrin-1 0.0121 0.0465 0.1424
Echinococcus granulosus ubiquitin specific protease 41 0.0045 0.0131 0.0126
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0156 0.0615 0.1616
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0106 0.0176
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0045 0.0131 0.0367
Plasmodium falciparum serine repeat antigen 1 0.0156 0.0615 0.1944
Plasmodium falciparum protein serine/threonine kinase-1 0.0074 0.0257 0.0702
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.2314 0.9993 0.9993
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0026 0.0052 0.0016
Echinococcus multilocularis centrin 2 0.0121 0.0465 0.046
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0045 0.0131 0.0126
Entamoeba histolytica calpain family cysteine protease, putative 0.0249 0.1018 0.3346
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0027 0.0055 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0118 0.0217
Trypanosoma brucei proteasome beta 6 subunit 0.0069 0.0238 0.0577
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0074 0.0257 0.04
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0249 0.1018 0.3388
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0039 0.0106 0.0069
Trypanosoma cruzi I/6 autoantigen, putative 0.0121 0.0465 0.0777
Trypanosoma cruzi conserved protein 0.0249 0.1018 0.178
Onchocerca volvulus 0.0156 0.0615 0.0966
Loa Loa (eye worm) hypothetical protein 0.0032 0.0076 0.0081
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0026 0.0052 0.0016
Loa Loa (eye worm) hypothetical protein 0.0033 0.0079 0.0083
Loa Loa (eye worm) calmodulin-like protein 0.0121 0.0465 0.0491
Leishmania major cathepsin L-like protease 0.0784 0.3346 0.9468
Echinococcus multilocularis tumor protein p63 0.029 0.1199 0.1194
Plasmodium falciparum serine repeat antigen 5 0.0156 0.0615 0.1944
Giardia lamblia Cathepsin L precursor 0.0156 0.0615 0.2683
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0249 0.1018 0.178
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0689 0.2933 1
Schistosoma mansoni calmodulin 0.0121 0.0465 0.043
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0784 0.3346 0.9468
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0027 0.0055 0.0018
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0066 0.0222 0.0531
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0027 0.0055 0.0033
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0066 0.0222 0.0582
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0027 0.0055 0.0008
Leishmania major centrin, putative 0.0121 0.0465 0.1225
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0827 0.3532 0.6341
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0045 0.0131 0.0125
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0121 0.0465 0.046
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0156 0.0615 0.0649
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0027 0.0055 0.0058
Plasmodium falciparum serine repeat antigen 3 0.0156 0.0615 0.1944
Echinococcus multilocularis caspase 2 0.0041 0.0118 0.0112
Entamoeba histolytica calpain large subunit domain III containing protein 0.0578 0.2451 0.8327
Toxoplasma gondii proteasome beta subunit 0.0027 0.0055 0.0063
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0062 0.0207 0.0309
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0033 0.0079 0.0083
Echinococcus multilocularis caspase 8 0.0041 0.0118 0.0112
Echinococcus granulosus calcium uptake protein 1 0.0123 0.0472 0.0466
Echinococcus granulosus calpain 7 C02 family 0.0827 0.3532 0.3528
Leishmania major proteasome beta 2 subunit, putative 0.0066 0.0222 0.0531
Schistosoma mansoni hypothetical protein 0.0121 0.0465 0.043
Loa Loa (eye worm) hypothetical protein 0.0156 0.0615 0.0649
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0784 0.3346 0.9468
Echinococcus multilocularis proteasome subunit beta type 6 0.0027 0.0055 0.0049
Entamoeba histolytica cysteine protease, putative 0.0689 0.2933 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0827 0.3532 0.6341
Trypanosoma brucei I/6 autoantigen 0.0121 0.0465 0.1225
Echinococcus granulosus EF hand domain containing family member A2 0.0123 0.0472 0.0466
Schistosoma mansoni lamin 0.0033 0.0079 0.0042
Echinococcus multilocularis cathepsin L 0.0156 0.0615 0.0609
Echinococcus granulosus programmed cell death protein 0.0121 0.0465 0.046
Trichomonas vaginalis conserved hypothetical protein 0.0121 0.0465 0.1424
Loa Loa (eye worm) hypothetical protein 0.0121 0.0465 0.0491
Loa Loa (eye worm) hypothetical protein 0.0041 0.0118 0.0124
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0027 0.0055 0.0053
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.004 0.0111 0.0117
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0156 0.0615 0.1944
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0249 0.1018 0.178
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0027 0.0055 0.0058
Schistosoma mansoni centrin 0.0121 0.0465 0.043
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0689 0.2933 1
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0045 0.0131 0.0172
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0118 0.0188
Leishmania major kinesin, putative 0.0578 0.2451 0.6908
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0249 0.1018 0.178
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0156 0.0615 0.0649
Onchocerca volvulus 0.0473 0.1993 0.3335
Echinococcus multilocularis cathepsin L cysteine protease 0.0689 0.2933 0.2929
Giardia lamblia Cathepsin L precursor 0.0156 0.0615 0.2683
Leishmania major programmed cell death 6 protein-like protein 0.0121 0.0465 0.1225
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0121 0.0465 0.1225
Onchocerca volvulus 0.0033 0.0079 0.0046
Plasmodium vivax serine-repeat antigen (SERA) 0.0156 0.0615 0.1616
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0027 0.0055 0.0053
Schistosoma mansoni Mername-AA248 (C02 family) 0.0827 0.3532 0.351
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0041 0.0118 0.0217
Leishmania major cathepsin L-like protease 0.0689 0.2933 0.8286
Loa Loa (eye worm) calpain family protein 1 0.1614 0.6952 0.7344
Echinococcus granulosus cysteine protease 0.0372 0.1554 0.1549
Mycobacterium ulcerans proteasome PrcA 0.0027 0.0055 0.0249
Entamoeba histolytica cysteine protease, putative 0.0372 0.1554 0.521
Brugia malayi proteasome subunit beta type 1 0.0069 0.0238 0.0238
Leishmania major cytochrome p450-like protein 0.0041 0.0114 0.022
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0207 0.0529
Loa Loa (eye worm) hypothetical protein 0.0039 0.0106 0.0112
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0156 0.0615 0.1944
Trypanosoma brucei protein kinase, putative 0.0062 0.0207 0.0488
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0156 0.0615 0.058
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0784 0.3346 0.9468
Schistosoma mansoni axis inhibition protein axin 0.0039 0.0106 0.0069
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0025 0.0048 0.0042
Echinococcus granulosus regulator of G protein signaling 3 0.0039 0.0106 0.01
Echinococcus multilocularis EF hand domain containing family member A2 0.0123 0.0472 0.0466
Echinococcus granulosus caspase 8 0.0041 0.0118 0.0112
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0156 0.0615 0.1616
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0689 0.2933 1
Onchocerca volvulus 0.0043 0.0122 0.012
Onchocerca volvulus 0.1365 0.5871 1
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0249 0.1018 0.2808
Giardia lamblia Encystation-specific protease 0.0156 0.0615 0.2683
Brugia malayi Cathepsin L-like precursor 0.0689 0.2933 0.3089
Trypanosoma brucei calmodulin, putative 0.0123 0.0472 0.1245
Trypanosoma cruzi Aph-1 protein, putative 0.005 0.0153 0.0211
Trichomonas vaginalis calmodulin-2, putative 0.0121 0.0465 0.1424
Echinococcus multilocularis cysteine protease 0.0689 0.2933 0.2929
Echinococcus multilocularis calpain 5 0.0827 0.3532 0.3528
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0054 0.0171 0.0165
Trypanosoma brucei calmodulin, putative 0.0121 0.0465 0.1225
Onchocerca volvulus 0.0123 0.0472 0.0721
Brugia malayi Cathepsin L-like precursor 0.0689 0.2933 0.3089
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0249 0.1018 0.3346
Loa Loa (eye worm) hypothetical protein 0.0039 0.0106 0.0112
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0106 0.0176
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0106 0.0176
Trypanosoma brucei centrin, putative 0.0121 0.0465 0.1225
Brugia malayi Papain family cysteine protease containing protein 0.0156 0.0615 0.0636
Brugia malayi follicle stimulating hormone receptor 0.028 0.1153 0.1206
Loa Loa (eye worm) hypothetical protein 0.2192 0.9466 1
Brugia malayi EF hand family protein 0.0123 0.0472 0.0485
Mycobacterium ulcerans aldehyde dehydrogenase 0.0054 0.0171 0.1823
Loa Loa (eye worm) cysteine protease 0.0689 0.2933 0.3098
Entamoeba histolytica cysteine protease, putative 0.0372 0.1554 0.521
Brugia malayi Cytochrome P450 family protein 0.0041 0.0114 0.0106
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0027 0.0055 0.0033
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1291 0.5548 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0784 0.3346 0.9468
Leishmania major calmodulin, putative 0.0121 0.0465 0.1225
Loa Loa (eye worm) cytochrome P450 family protein 0.0061 0.0204 0.0216
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0074 0.0257 0.04
Trypanosoma cruzi cysteine peptidase, putative 0.0689 0.2933 0.5254
Brugia malayi Proteasome A-type and B-type family protein 0.0027 0.0055 0.0044
Echinococcus granulosus cathepsin L 0.0372 0.1554 0.1549
Schistosoma mansoni reticulocalbin 0.0121 0.0465 0.043
Schistosoma mansoni cathepsin s 0.0216 0.0877 0.0844
Echinococcus granulosus calpain 5 0.0827 0.3532 0.3528
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0027 0.0055 0.0053
Loa Loa (eye worm) hypothetical protein 0.0156 0.0615 0.0649

Activities

Activity type Activity value Assay description Source Reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c9 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 2.511886432 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp3a4 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 6.309573445 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp1a2 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 12.58925412 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c19 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 15.84893192 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2d6 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
Potency (functional) = 0.7943 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 0.7943 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293. (Class of assay: confirmatory) ChEMBL. No reference
Potency (ADMET) = 2.5119 um PUBCHEM_BIOASSAY: qHTS Assay for Activators of Cytochrome P450 3A4. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Potency (ADMET) = 2.5119 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of CDC-like Kinase 4 (ADP-FP Assay). (Class of assay: confirmatory) [Related pubchem assays: 1771, 1770 ] ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference
Potency (ADMET) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C19. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Potency (functional) = 14.1254 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of CDC-like Kinase 4 (ADP-Glo Assay). (Class of assay: confirmatory) [Related pubchem assays: 1379 ] ChEMBL. No reference
Potency (functional) = 15.8489 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of CDC-like Kinase 4 (Kinase-Glo Assay). (Class of assay: confirmatory) [Related pubchem assays: 1379 ] ChEMBL. No reference
Potency (ADMET) = 15.8489 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2D6. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Potency (functional) = 19.9526 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 19.9526 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Ubiquitin-specific Protease USP2a. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 31.6228 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of 15-hLO-2 (15-human lipoxygenase 2). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2312, AID2537, AID2702] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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