Detailed information for compound 1693463

Basic information

Technical information
  • TDR Targets ID: 1693463
  • Name: L-646991
  • MW: 1030.12 | Formula: C49H71N7O17
  • H donors: 14 H acceptors: 16 LogP: 0.71 Rotable bonds: 16
    Rule of 5 violations (Lipinski): 4
  • SMILES: CCCCCCCCOc1ccc(cc1)C(=O)N[C@H]1C[C@@H](O)[C@@H](O)NC(=O)[C@@H]2[C@@H](O)[C@H](CN2C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]2N(C(=O)[C@@H](NC1=O)[C@H](O)C)C[C@@H](C2)O)[C@@H]([C@H](c1ccc(cc1)O)O)O)[C@H](O)C)C
  • InChi: 1S/C49H71N7O17/c1-5-6-7-8-9-10-19-73-31-17-13-28(14-18-31)42(65)50-32-21-34(61)45(68)54-47(70)38-39(62)24(2)22-56(38)49(72)36(26(4)58)52-46(69)37(41(64)40(63)27-11-15-29(59)16-12-27)53-44(67)33-20-30(60)23-55(33)48(71)35(25(3)57)51-43(32)66/h11-18,24-26,30,32-41,45,57-64,68H,5-10,19-23H2,1-4H3,(H,50,65)(H,51,66)(H,52,69)(H,53,67)(H,54,70)/t24-,25+,26+,30+,32-,33-,34+,35-,36-,37-,38-,39-,40-,41-,45+/m0/s1
  • InChiKey: ZKZKCEAHVFVZDJ-MTUMARHDSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0021 0.0006 0.006
Brugia malayi Dopamine receptor protein 1 0.0037 0.002 0.0217
Schistosoma mansoni amine GPCR 0.0037 0.002 0.0147
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0381 0.0302 0.2644
Schistosoma mansoni hypothetical protein 0.0017 0.0003 0.0016
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0021 0.0006 0.0525
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0021 0.0237
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0072 0.0048 0.0048
Loa Loa (eye worm) phosphatidylinositol 3-kinase catalytic subunit gamma 0.0057 0.0036 0.0304
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0072 0.0048 0.0556
Echinococcus multilocularis allatostatin A receptor 0.0037 0.002 0.002
Brugia malayi G protein-coupled receptor F59B2.13 0.0037 0.002 0.0217
Toxoplasma gondii histone lysine methyltransferase SET1 0.0118 0.0086 0.1057
Schistosoma mansoni 6-phosphofructokinase 0.0129 0.0095 0.0737
Trichomonas vaginalis PIKK family atypical protein kinase 0.0601 0.0483 0.5589
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0103 0.0073 0.0073
Schistosoma mansoni survival motor neuron protein 0.0165 0.0125 0.097
Trichomonas vaginalis casein kinase II beta chain, putative 0.0043 0.0025 0.028
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.003 0.0333
Toxoplasma gondii hypothetical protein 0.0023 0.0008 0.0087
Trichomonas vaginalis casein kinase II beta chain, putative 0.0043 0.0025 0.028
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0208 0.016 0.1251
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0037 0.002 0.002
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0162 0.0123 0.3917
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0000081462
Onchocerca volvulus 0.0037 0.002 0.0553
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0041 0.0471
Leishmania major casein kinase II, putative 0.0162 0.0123 0.0335
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0313 0.0247 0.0709
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0018
Echinococcus granulosus tm gpcr rhodopsin 0.0037 0.002 0.002
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0313 0.0247 0.0247
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.003 0.3049
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0037 0.002 0.002
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0021 0.0006 0.0061
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0049 0.003 0.3049
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0208 0.016 0.1849
Echinococcus multilocularis geminin 0.0543 0.0436 0.0436
Schistosoma mansoni hypothetical protein 0.0543 0.0436 0.3408
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0006 0.0062
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0645 0.0519 0.6217
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0021 0.0006 0.0062
Leishmania major stearic acid desaturase, putative 0.0427 0.034 0.0931
Trichomonas vaginalis CMGC family protein kinase 0.0162 0.0123 0.1414
Trichomonas vaginalis casein kinase II beta chain, putative 0.0043 0.0025 0.028
Leishmania major fatty acid desaturase, putative 0.0035 0.0017 0.0047
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0072 0.0048 0.0139
Onchocerca volvulus 0.0037 0.002 0.0553
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0015 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0008 0.0083
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0021 0.0006 0.031
Brugia malayi Regulator of G protein signaling domain containing protein 0.0023 0.0008 0.0079
Echinococcus granulosus alpha 1A adrenergic receptor 0.0037 0.002 0.002
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.1014 0.0823 0.2366
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.027 0.0211 0.0606
Echinococcus granulosus serotonin receptor 0.0037 0.002 0.002
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0954 0.0774 0.9299
Trypanosoma cruzi casein kinase II, putative 0.0162 0.0123 0.0352
Trichomonas vaginalis PIKK family atypical protein kinase 0.0954 0.0774 0.8958
Leishmania major fatty acid desaturase, putative,sphingolipid delta 4 desaturase, putative 0.0035 0.0017 0.0047
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0313 0.0247 0.7914
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0564 0.0453 0.5241
Loa Loa (eye worm) hypothetical protein 0.0059 0.0037 0.0319
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0008 0.0061
Echinococcus granulosus Regulator of G protein signaling 20 0.0023 0.0008 0.0008
Brugia malayi DKFZp564C0469 protein 0.0021 0.0006 0.0057
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0015 0.0002 0.0002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.002 0.0147
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.1064 0.0864 0.2484
Echinococcus granulosus cpg binding protein 0.0065 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Plasmodium vivax unspecified product 0.0162 0.0123 0.3917
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0019 0.0141
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0037 0.002 0.0217
Loa Loa (eye worm) hypothetical protein 0.0032 0.0015 0.0126
Schistosoma mansoni biogenic amine receptor 0.0037 0.002 0.0147
Echinococcus multilocularis voltage dependent calcium channel 0.0038 0.002 0.002
Loa Loa (eye worm) phosphatidylinositol 3 0.0967 0.0784 0.6872
Schistosoma mansoni hypothetical protein 0.0037 0.002 0.0147
Trichomonas vaginalis CMGC family protein kinase 0.006 0.0039 0.0442
Mycobacterium ulcerans hypothetical protein 0.0049 0.003 0.3049
Brugia malayi Serotonin receptor 0.0037 0.002 0.0217
Schistosoma mansoni axis inhibition protein axin 0.0023 0.0008 0.0053
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0313 0.0247 0.3039
Echinococcus granulosus tumor protein p63 0.0401 0.0318 0.0318
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.1025 0.0832 0.9633
Brugia malayi AMP-binding enzyme family protein 0.0049 0.003 0.0333
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.003 0.1798
Echinococcus granulosus glycogen synthase kinase 3 beta 0.006 0.0039 0.0039
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0967 0.0784 0.9425
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0037 0.002 0.0147
Trichomonas vaginalis PIKK family atypical protein kinase 0.0998 0.081 0.9373
Echinococcus granulosus geminin 0.0543 0.0436 0.0436
Brugia malayi exodeoxyribonuclease III family protein 0.0058 0.0036 0.0412
Leishmania major protein kinase ck2 regulatory subunit, putative 0.0043 0.0025 0.0067
Brugia malayi Delta5 fatty acid desaturase 0.0035 0.0017 0.0191
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0019 0.0005 0.0013
Loa Loa (eye worm) hypothetical protein 0.0088 0.0061 0.053
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0014 0.0001 0.0001
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0208 0.016 0.1853
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0023 0.0008 0.0441
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0139 0.0103 0.0804
Echinococcus granulosus GPCR family 2 0.0032 0.0015 0.0015
Toxoplasma gondii exonuclease III APE 0.0058 0.0036 0.044
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.0003 0.0003
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0038 0.002 0.002
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0106 0.0076 0.0076
Echinococcus granulosus G protein coupled receptor 139 0.0037 0.002 0.002
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0478 0.0383 0.11
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0015 0.0124
Loa Loa (eye worm) phosphatidylinositol 3 0.0208 0.016 0.14
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0017 0.0003 0.0018
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0008 0.0053
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0008 0.0053
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0036 0.1145
Echinococcus multilocularis casein kinase ii subunit beta 0.0043 0.0025 0.0025
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0139 0.0103 0.0103
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Trichomonas vaginalis PIKK family atypical protein kinase 0.066 0.0532 0.6156
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0038 0.002 0.002
Echinococcus multilocularis G protein coupled receptor 139 0.0037 0.002 0.002
Giardia lamblia Phosphatidylinositol 4-kinase 0.0208 0.016 0.1871
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0037 0.002 0.0165
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0855 0.0692 0.8013
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0035 0.0018 0.1321
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0381 0.0302 0.2644
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0478 0.0383 0.4423
Echinococcus multilocularis muscleblind protein 0.0149 0.0112 0.0112
Echinococcus multilocularis neuropeptide FF receptor 2 0.0037 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0015 0.0002 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0208 0.016 0.1853
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.1003 0.0814 0.9425
Echinococcus granulosus Sphingolipid delta4 desaturase DES1 0.0035 0.0017 0.0017
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.002 0.002
Brugia malayi hypothetical protein 0.0021 0.0006 0.0057
Mycobacterium ulcerans linoleoyl-CoA desaturase, DesA3 0.0035 0.0017 0.1751
Echinococcus multilocularis polycomb protein SCMH1 0.0048 0.0028 0.0028
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0035 0.0018 0.0207
Loa Loa (eye worm) phosphatidylinositol 3 0.0208 0.016 0.14
Echinococcus multilocularis neuropeptide receptor 0.0037 0.002 0.002
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0021 0.0237
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0072 0.0048 0.0556
Echinococcus granulosus neutral alpha glucosidase AB 0.0039 0.0021 0.0021
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0037 0.002 0.0147
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0012 0.0128
Loa Loa (eye worm) hypothetical protein 0.0049 0.003 0.0252
Echinococcus granulosus neuropeptide receptor A26 0.0037 0.002 0.002
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0001 0.0000081462
Loa Loa (eye worm) hypothetical protein 0.0208 0.016 0.14
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0032 0.0015 0.0015
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.002 0.0147
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0037 0.002 0.0147
Echinococcus granulosus dro:myosuppressin receptor 0.0037 0.002 0.002
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0015 0.0164
Trichomonas vaginalis conserved hypothetical protein 0.0088 0.0061 0.0705
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0006 0.0062
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0037 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0043
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0001 0.0005
Schistosoma mansoni hypothetical protein 0.0037 0.002 0.0147
Echinococcus granulosus regulator of G protein signaling 7 0.0023 0.0008 0.0008
Loa Loa (eye worm) CMGC/GSK protein kinase 0.006 0.0039 0.0332
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0381 0.0302 0.8891
Loa Loa (eye worm) phosphatidylinositol 3 0.0208 0.016 0.14
Brugia malayi PXA domain containing protein 0.0024 0.0009 0.0095
Giardia lamblia Kinase, CMGC GSK 0.006 0.0039 0.0398
Trichomonas vaginalis PIKK family atypical protein kinase 0.0976 0.0792 0.9166
Schistosoma mansoni intermediate filament proteins 0.0032 0.0015 0.0111
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.002
Leishmania major fatty acid desaturase, putative,sphingolipid delta 4 desaturase, putative 0.0035 0.0017 0.0047
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0035 0.0018 0.0538
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0059
Echinococcus granulosus expressed conserved protein 0.0193 0.0147 0.0147
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0032 0.0015 0.0112
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0208 0.016 0.1849
Brugia malayi Glycosyl hydrolases family 31 protein 0.0175 0.0133 0.1533
Echinococcus granulosus tm gpcr rhodopsin 0.0037 0.002 0.002
Echinococcus multilocularis lysosomal alpha glucosidase 0.0175 0.0133 0.0133
Brugia malayi hypothetical protein 0.0079 0.0054 0.062
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.0001 0.0002
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0208 0.016 0.192
Trichomonas vaginalis conserved hypothetical protein 0.0343 0.0271 0.3136
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0043 0.0025 0.0294
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0403 0.032 0.032
Giardia lamblia Kinase, CMGC GSK 0.006 0.0039 0.0398
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.0001 0.0009
Brugia malayi AMP-binding enzyme family protein 0.0049 0.003 0.0333
Toxoplasma gondii ATPase, AAA family protein 0.0021 0.0006 0.0061
Leishmania major hypothetical protein, conserved 0.4449 0.3649 1
Brugia malayi Cytochrome P450 family protein 0.0023 0.0008 0.0081
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0018 0.0198
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0032 0.0015 0.0171
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0313 0.0247 0.1926
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.003 0.3049
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0313 0.0247 0.2851
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0313 0.0247 0.0247
Brugia malayi AMP-binding enzyme family protein 0.0049 0.003 0.0333
Schistosoma mansoni neuropeptide f receptor 76f 0.0037 0.002 0.0147
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0015 0.0001 0.0004
Schistosoma mansoni neuropeptide F-like receptor 0.0037 0.002 0.0147
Loa Loa (eye worm) hypothetical protein 0.0037 0.0019 0.0162
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0037 0.002 0.0217
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0072 0.0048 0.0556
Loa Loa (eye worm) hypothetical protein 0.0403 0.032 0.2804
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0043 0.0025 0.0703
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0162 0.0123 0.1067
Trypanosoma cruzi sphingolipid delta 4 desaturase, putative 0.0035 0.0017 0.0049
Echinococcus multilocularis fmrfamide receptor 0.0037 0.002 0.002
Schistosoma mansoni biogenic amine (5HT) receptor 0.0037 0.002 0.0147
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0037 0.002 0.002
Loa Loa (eye worm) phosphatidylinositol 3 0.027 0.0211 0.1844
Trichomonas vaginalis CAMK family protein kinase 0.0227 0.0176 0.2032
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0786 0.0635 0.0635
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0023 0.0008 0.0053
Echinococcus multilocularis sterol regulatory element binding protein 0.0088 0.0061 0.0061
Loa Loa (eye worm) gastrulation defective protein 1 0.0155 0.0116 0.1011
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.003 0.008
Onchocerca volvulus 0.0021 0.0006 0.0146
Trypanosoma cruzi fatty acid desaturase, putative 0.0035 0.0017 0.0049
Brugia malayi bHLH-PAS transcription factor 0.0043 0.0024 0.0269
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.002 0.002
Mycobacterium ulcerans putative regulatory protein 0.0023 0.0008 0.0748
Brugia malayi Tachykinin-like peptides receptor 99D 0.0037 0.002 0.0217
Leishmania major acetyl-CoA synthetase, putative 0.0014 0.0001 0.0002
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.002 0.002
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.006 0.0039 0.0296
Entamoeba histolytica hypothetical protein 0.0023 0.0008 0.0079
Schistosoma mansoni hypothetical protein 0.0543 0.0436 0.3408
Brugia malayi Dopamine receptor protein 2 0.0037 0.002 0.0217
Trypanosoma cruzi fatty acid desaturase, putative 0.0392 0.0311 0.0895
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Echinococcus multilocularis neuropeptide s receptor 0.0037 0.002 0.002
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0008 0.0227
Trichomonas vaginalis CAMK family protein kinase 0.0227 0.0176 0.2032
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0028 0.0213
Toxoplasma gondii LsmAD domain-containing protein 0.005 0.003 0.0365
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.1025 0.0832 0.228
Entamoeba histolytica phosphofructokinase, putative 0.0129 0.0095 0.109
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0037 0.002 0.0147
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0012 0.0128
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0021 0.0006 0.0057
Onchocerca volvulus 0.005 0.003 0.0858
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0633 0.051 0.6119
Echinococcus granulosus expressed protein 0.0443 0.0353 0.0353
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0018 0.1051
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0037 0.002 0.0217
Loa Loa (eye worm) hypothetical protein 0.0049 0.003 0.0252
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0035 0.0018 0.9054
Trichomonas vaginalis CMGC family protein kinase 0.0162 0.0123 0.1414
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0313 0.0247 0.1926
Plasmodium vivax glycogen synthase kinase 3, putative 0.006 0.0039 0.1217
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Schistosoma mansoni ap endonuclease 0.0058 0.0036 0.0279
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0059
Trichomonas vaginalis casein kinase II beta chain, putative 0.0043 0.0025 0.028
Trichomonas vaginalis casein kinase II beta chain, putative 0.0043 0.0025 0.028
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0006 0.0062
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.003 0.0333
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0037 0.002 0.0147
Echinococcus multilocularis neuropeptides capa receptor 0.0037 0.002 0.002
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0043 0.0025 0.007
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0129 0.0095 0.0273
Schistosoma mansoni hypothetical protein 0.0037 0.002 0.0147
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0049 0.003 0.1798
Trichomonas vaginalis PIKK family atypical protein kinase 0.0998 0.081 0.9373
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0012 0.0128
Schistosoma mansoni hypothetical protein 0.0032 0.0015 0.0111
Onchocerca volvulus 0.0037 0.002 0.0553
Onchocerca volvulus 0.0059 0.0037 0.1072
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0036 0.0019 0.0019
Trypanosoma cruzi fatty acid desaturase, putative 0.0392 0.0311 0.0895
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0018 0.1051
Loa Loa (eye worm) hypothetical protein 0.0611 0.0492 0.4305
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0037 0.002 0.0147
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0011 0.0079
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0036 0.0019 0.0019
Chlamydia trachomatis DNA ligase 0.0021 0.0006 0.2517
Leishmania major phosphatidylinositol 4-kinase, putative 0.0208 0.016 0.0439
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0035 0.0018 0.0538
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0079 0.0054 0.0054
Entamoeba histolytica hypothetical protein 0.0208 0.016 0.1849
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0567 0.0455 0.5263
Brugia malayi hypothetical protein 0.0037 0.002 0.0217
Trichomonas vaginalis PIKK family atypical protein kinase 0.1003 0.0814 0.9425
Echinococcus granulosus g protein coupled receptor 0.0037 0.002 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.1025 0.0832 0.9633
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.0003 0.0003
Trypanosoma brucei Casein kinase II 0.0162 0.0123 0.1463
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Echinococcus granulosus hypothetical protein 0.0037 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0043
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0018 0.0198
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0021 0.0237
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.0008 0.0061
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0072 0.0048 0.0573
Plasmodium falciparum casein kinase II beta chain 0.0043 0.0025 0.0767
Loa Loa (eye worm) hypothetical protein 0.0037 0.0019 0.0162
Brugia malayi Uncoordinated protein 44 0.0017 0.0003 0.0024
Treponema pallidum exodeoxyribonuclease (exoA) 0.0058 0.0036 0.3436
Trypanosoma brucei glucosidase, putative 0.0039 0.0021 0.0241
Echinococcus granulosus beta-adrenergic receptor kinase 0.0027 0.0011 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0622 0.0501 0.5797
Echinococcus multilocularis Fatty acid desaturase, type 1 0.0035 0.0017 0.0017
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0139 0.0103 0.0804
Echinococcus multilocularis expressed protein 0.0443 0.0353 0.0353
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.0001 0.0002
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0039 0.0021 0.0248
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.1566 0.1277 0.1277
Plasmodium falciparum stearoyl-CoA desaturase 0.0392 0.0311 1
Echinococcus granulosus lamin 0.0032 0.0015 0.0015
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0018 0.015
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0313 0.0247 0.2848
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.002 0.0147
Echinococcus multilocularis nibrin 0.0021 0.0006 0.0006
Brugia malayi hypothetical protein 0.0037 0.002 0.0217
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0088 0.0061 0.053
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0017 0.0003 0.0016
Loa Loa (eye worm) histone methyltransferase 0.002 0.0006 0.0043
Onchocerca volvulus 0.0043 0.0024 0.0684
Echinococcus granulosus nuclear factor of activated T cells 5 0.0087 0.0061 0.0061
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0015 0.0164
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0037 0.002 0.0165
Schistosoma mansoni hypothetical protein 0.0472 0.0377 0.2948
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0087 0.0061 0.0061
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0037 0.002 0.0147
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0038 0.002 0.0152
Entamoeba histolytica acyl-coA synthetase, putative 0.0049 0.003 0.0333
Trichomonas vaginalis PIKK family atypical protein kinase 0.0967 0.0784 0.908
Trichomonas vaginalis phosphofructokinase, putative 0.0129 0.0095 0.1094
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0199 0.0153 0.0153
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0017 0.0003 0.0017
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0037 0.002 0.002
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.002 0.002
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0043 0.0025 0.0276
Echinococcus granulosus aryl hydrocarbon receptor 0.0015 0.0001 0.0001
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0028 0.0213
Echinococcus granulosus polycomb protein SCMH1 0.0048 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0068 0.0045 0.0389
Echinococcus multilocularis neuropeptides capa receptor 0.0037 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0037 0.002 0.002
Loa Loa (eye worm) melatonin receptor type 1A 0.0037 0.002 0.0165
Brugia malayi Bloom's syndrome protein homolog 0.0025 0.001 0.0101
Mycobacterium ulcerans putative regulatory protein 0.0043 0.0024 0.2465
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0021 0.0006 0.0016
Trichomonas vaginalis casein kinase II beta chain, putative 0.0043 0.0025 0.028
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0021 0.0006 0.0062
Echinococcus granulosus neuropeptides capa receptor 0.0037 0.002 0.002
Schistosoma mansoni cpg binding protein 0.0065 0.0043 0.0328
Trypanosoma brucei Casein kinase II subunit beta, putative 0.0043 0.0025 0.0286
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.002 0.002
Brugia malayi Protein kinase domain containing protein 0.0381 0.0302 0.3492
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.003 0.008
Schistosoma mansoni opsin-like receptor 0.0037 0.002 0.0147
Schistosoma mansoni hypothetical protein 0.0032 0.0015 0.0111
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.003 0.1798
Brugia malayi Fatty acid desaturase family protein 0.0035 0.0017 0.0191
Trichomonas vaginalis PIKK family atypical protein kinase 0.0976 0.0792 0.9166
Schistosoma mansoni lamin 0.0032 0.0015 0.0111
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0786 0.0635 0.0635
Echinococcus granulosus neuropeptides capa receptor 0.0037 0.002 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.1003 0.0814 0.9425
Schistosoma mansoni hypothetical protein 0.0165 0.0125 0.097
Trichomonas vaginalis PIKK family atypical protein kinase 0.1003 0.0814 0.9425
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0004
Brugia malayi hypothetical protein 0.0037 0.002 0.0217
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0002
Schistosoma mansoni hypothetical protein 0.0085 0.0059 0.0453
Brugia malayi M-phase phosphoprotein, mpp8 0.0119 0.0087 0.0996
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0072 0.0048 0.0556
Trichomonas vaginalis PIKK family atypical protein kinase 0.1025 0.0832 0.9633
Schistosoma mansoni myosin xvIII 0.0037 0.002 0.0147
Schistosoma mansoni DNA ligase IV 0.0021 0.0006 0.0039
Echinococcus granulosus serine protein kinase ATM 0.0569 0.0457 0.0457
Onchocerca volvulus 0.0062 0.004 0.1149
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0072 0.0048 0.0556
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Brugia malayi follicle stimulating hormone receptor 0.031 0.0244 0.2817
Onchocerca volvulus 0.0119 0.0087 0.2536
Trichomonas vaginalis conserved hypothetical protein 0.0611 0.0492 0.5689
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0023 0.0008 0.0748
Echinococcus granulosus neuropeptide FF receptor 2 0.0037 0.002 0.002
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0021 0.0237
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0021 0.006
Loa Loa (eye worm) RecQ helicase 0.0025 0.001 0.0076
Schistosoma mansoni biogenic amine receptor 0.0037 0.002 0.0147
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0037 0.002 0.002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.002 0.0147
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0227 0.0176 0.0176
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0032 0.0015 0.0166
Echinococcus granulosus muscleblind protein 0.0149 0.0112 0.0112
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0037 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Trypanosoma cruzi FHA domain containing protein, putative 0.0021 0.0006 0.0016
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0072 0.0048 0.0373
Echinococcus multilocularis serine protein kinase ATM 0.0569 0.0457 0.0457
Leishmania major phosphatidylinositol kinase, putative 0.0208 0.016 0.0439
Schistosoma mansoni topbp1 0.0021 0.0006 0.0039
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0043 0.0025 0.0703
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0552 0.0443 0.1273
Mycobacterium leprae Possible regulatory protein 0.0015 0.0001 0.0025
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0003 0.0014
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0129 0.0095 1
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0038 0.002 0.0224
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1064 0.0864 1
Loa Loa (eye worm) phosphatidylinositol 3 0.1025 0.0832 0.7292
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0008 0.0441
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0058 0.0036 0.0104
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0058 0.0036 1
Schistosoma mansoni alpha-glucosidase 0.0151 0.0113 0.0879
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.004
Plasmodium vivax stearoyl-CoA desaturase (acyl-CoA desaturase, faty acid desaturase), putative 0.0392 0.0311 1
Schistosoma mansoni amine GPCR 0.0037 0.002 0.0147
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0208 0.016 0.1973
Mycobacterium ulcerans transmembrane alkane 1-monooxygenase AlkB 0.0035 0.0017 0.1751
Brugia malayi mbt repeat family protein 0.0048 0.0028 0.0316
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0058 0.0036 0.0412
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Echinococcus multilocularis neuropeptide receptor A26 0.0037 0.002 0.002
Trichomonas vaginalis guanylate cyclase, putative 0.0015 0.0001 0.0009
Entamoeba histolytica phosphofructokinase, putative 0.0129 0.0095 0.109
Trichomonas vaginalis sucrase-isomaltase, putative 0.0039 0.0021 0.0237
Loa Loa (eye worm) hypothetical protein 0.0552 0.0443 0.3876
Trichomonas vaginalis casein kinase II beta chain, putative 0.0043 0.0025 0.028
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0208 0.016 0.0461
Brugia malayi Protein kinase domain containing protein 0.0021 0.0006 0.0063
Loa Loa (eye worm) calcium channel 0.0038 0.002 0.017
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.1014 0.0823 0.0823
Leishmania major fatty acid desaturase, putative,sphingolipid delta 4 desaturase, putative 0.0035 0.0017 0.0047
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0058 0.0036 0.0371
Leishmania major ATP-dependent phosphofructokinase 0.0129 0.0095 0.026
Schistosoma mansoni hypothetical protein 0.0085 0.0059 0.0453
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0048 0.0028 0.0213
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0227 0.0176 0.0176
Leishmania major delta-5 fatty acid desaturase 0.0035 0.0017 0.0047
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Echinococcus multilocularis cyclin dependent kinase 19 0.0159 0.0119 0.0119
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0313 0.0247 0.0709
Loa Loa (eye worm) intermediate filament protein 0.0032 0.0015 0.0124
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.003 0.0951
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0018 0.0198
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0001 0.0005
Brugia malayi Cytochrome P450 family protein 0.0035 0.0018 0.0198
Loa Loa (eye worm) hypothetical protein 0.0332 0.0262 0.2289
Brugia malayi Fatty acid desaturase family protein 0.0035 0.0017 0.0191
Schistosoma mansoni hypothetical protein 0.0079 0.0054 0.0419
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0035 0.0018 0.9054
Echinococcus granulosus Ankyrin 0.0017 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0032 0.0015 0.0111
Toxoplasma gondii GAF domain-containing protein 0.0023 0.0008 0.0087
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0058 0.0036 0.0036
Schistosoma mansoni topbp1 0.0021 0.0006 0.0039
Brugia malayi 6-phosphofructokinase 0.0129 0.0095 0.109
Echinococcus multilocularis g protein coupled receptor 0.0037 0.002 0.002
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0012 0.0128
Schistosoma mansoni opsin-like receptor 0.0037 0.002 0.0147
Echinococcus multilocularis transfer RNA-Lys 0.0043 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0039 0.0021 0.0176
Toxoplasma gondii ck2 beta subunit 0.0043 0.0025 0.0294
Echinococcus multilocularis sex peptide receptor 0.0037 0.002 0.002
Loa Loa (eye worm) CMGC/GSK protein kinase 0.006 0.0039 0.0332
Onchocerca volvulus 0.0427 0.034 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0001 0.0005
Echinococcus granulosus orexin receptor type 2 0.0037 0.002 0.002
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0208 0.016 0.1251
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0014 0.0001 0.0002
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0072 0.0048 0.0556
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0502 0.0402 0.4648
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0037 0.0019 0.1958
Brugia malayi G-protein coupled receptor 0.0037 0.002 0.0217
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0012 0.0128
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.1566 0.1277 0.1277
Echinococcus granulosus sterol regulatory element binding protein 0.0088 0.0061 0.0061
Leishmania major fatty acid desaturase, putative 0.0035 0.0017 0.0047
Plasmodium falciparum casein kinase II beta chain 0.0043 0.0025 0.0767
Brugia malayi Calcitonin receptor-like protein seb-1 0.01 0.0071 0.0816
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0001 0.0005
Loa Loa (eye worm) Csnk2b protein 0.0043 0.0025 0.0209
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0037 0.002 0.002
Loa Loa (eye worm) RGS-3 protein 0.0023 0.0008 0.0059
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0014 0.0001 0.0001
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0018 0.0198
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0043 0.0025 0.007
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0072 0.0048 0.0556
Echinococcus granulosus lysosomal alpha glucosidase 0.0175 0.0133 0.0133
Onchocerca volvulus 0.0048 0.0028 0.0803
Loa Loa (eye worm) MBCTL1 0.0054 0.0034 0.0286
Trypanosoma cruzi polo-like protein kinase, putative 0.0227 0.0176 0.0505
Brugia malayi Protein kinase domain containing protein 0.0159 0.0119 0.1374
Schistosoma mansoni alpha-1 adrenergic receptor 0.0037 0.002 0.0147
Schistosoma mansoni cpg binding protein 0.0065 0.0043 0.0328
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0001 0.0002
Echinococcus multilocularis fmrfamide receptor 0.0037 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Trichomonas vaginalis PIKK family atypical protein kinase 0.0976 0.0792 0.9165
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0159 0.0119 0.104
Echinococcus granulosus Protein patched homolog 1 0.0088 0.0061 0.0061
Brugia malayi ORL1-like opioid receptor 0.0037 0.002 0.0217
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0041 0.0471
Trichomonas vaginalis PIKK family atypical protein kinase 0.0998 0.081 0.9373
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0208 0.016 0.016
Mycobacterium ulcerans hypothetical protein 0.0035 0.0017 0.1751
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0015 0.0001 0.0009
Echinococcus multilocularis neutral alpha glucosidase AB 0.0039 0.0021 0.0021
Plasmodium falciparum casein kinase 2, alpha subunit 0.0162 0.0123 0.3917
Echinococcus granulosus high voltage activated calcium channel beta 0.0103 0.0074 0.0074
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0381 0.0302 0.0302
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0008 0.0008
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0072 0.0048 0.0556
Brugia malayi hypothetical protein 0.0023 0.0008 0.0079
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0054 0.0034 0.0034
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0106 0.0076 0.0076
Brugia malayi SET domain containing protein 0.0016 0.0002 0.0015
Brugia malayi hypothetical protein 0.0194 0.0148 0.1706
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0008 0.0008
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0032 0.0015 0.0166
Trichomonas vaginalis CAMK family protein kinase 0.0227 0.0176 0.2032
Schistosoma mansoni adenoreceptor 0.0037 0.002 0.0147
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0043 0.0025 0.0276
Loa Loa (eye worm) CXXC zinc finger family protein 0.0062 0.004 0.0341
Trichomonas vaginalis CMGC family protein kinase 0.0162 0.0123 0.1414
Giardia lamblia Kinase, PLK 0.0227 0.0176 0.2058
Plasmodium falciparum GAF domain-related protein, putative 0.0023 0.0008 0.0227
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0072 0.0048 0.0139
Echinococcus multilocularis neuropeptide Y receptor 0.0037 0.002 0.002
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0001 0.0002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.002 0.0147
Onchocerca volvulus 0.0037 0.002 0.0553
Trichomonas vaginalis casein kinase II beta chain, putative 0.0043 0.0025 0.028
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0037 0.002 0.002
Plasmodium falciparum acyl-CoA synthetase 0.0037 0.0019 0.0593
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.003 0.1798
Brugia malayi Dopamine receptor 0.0037 0.002 0.0217
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0023 0.0008 0.0053
Trichomonas vaginalis CAMK family protein kinase 0.0227 0.0176 0.2032
Brugia malayi 6-phosphofructokinase 0.0129 0.0095 0.109
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0139 0.0103 0.1188
Brugia malayi hypothetical protein 0.0119 0.0087 0.0998
Echinococcus multilocularis g protein coupled receptor 0.0037 0.002 0.002
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.006 0.0039 0.0039
Brugia malayi Casein kinase II, alpha chain 0.0162 0.0123 0.141
Onchocerca volvulus 0.0015 0.0001 0.0012
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0072 0.0048 0.0556
Loa Loa (eye worm) hypothetical protein 0.0032 0.0015 0.0124
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0208 0.016 0.1251
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.1064 0.0864 1
Echinococcus granulosus protein kinase shaggy 0.006 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0037 0.0019 0.0162
Echinococcus granulosus g protein coupled receptor 0.0037 0.002 0.002
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0072 0.0048 0.0556
Loa Loa (eye worm) FAT-3 protein 0.0035 0.0017 0.0145
Trichomonas vaginalis casein kinase II beta chain, putative 0.0043 0.0025 0.028
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0058 0.0036 0.0099
Brugia malayi Serotonin receptor 0.0583 0.0468 0.5417
Loa Loa (eye worm) hypothetical protein 0.0149 0.0112 0.0971
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0001 0.0005
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0035 0.0018 0.0194
Echinococcus multilocularis Peptidase M, neutral zinc metallopeptidases, zinc binding site 0.0035 0.0017 0.0017
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0019 0.0141
Echinococcus multilocularis g-protein coupled receptor 0.0037 0.002 0.002
Echinococcus granulosus casein kinase ii subunit alpha 0.0162 0.0123 0.0123
Onchocerca volvulus 0.0037 0.002 0.0553
Schistosoma mansoni hypothetical protein 0.0061 0.0039 0.0298
Echinococcus multilocularis high voltage activated calcium channel beta 0.0103 0.0074 0.0074
Onchocerca volvulus 0.0037 0.002 0.0553
Toxoplasma gondii target of rapamycin (TOR), putative 0.0998 0.081 1
Loa Loa (eye worm) hypothetical protein 0.005 0.003 0.0259
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0017 0.0003 0.0003
Trichomonas vaginalis CMGC family protein kinase 0.0162 0.0123 0.1414
Echinococcus granulosus biogenic amine 5HT receptor 0.0037 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Onchocerca volvulus Netrin receptor homolog 0.0017 0.0003 0.0062
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0012 0.0128
Echinococcus multilocularis voltage dependent calcium channel 0.0038 0.002 0.002
Echinococcus granulosus dnaJ subfamily B 0.0472 0.0377 0.0377
Leishmania major delta-12 fatty acid desaturase 0.0035 0.0017 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0998 0.081 0.9373
Echinococcus granulosus neuropeptide Y receptor 0.0037 0.002 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0008 0.0083
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0017 0.0003 0.0023
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0037 0.002 0.0165
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Echinococcus granulosus Niemann Pick C1 protein 0.0205 0.0158 0.0158
Echinococcus multilocularis regulator of G protein signaling 3 0.0023 0.0008 0.0008
Echinococcus multilocularis aryl hydrocarbon receptor 0.0015 0.0001 0.0001
Echinococcus granulosus 7tm_1 domain containing protein 0.0037 0.002 0.002
Echinococcus multilocularis netrin receptor unc 5 0.0017 0.0003 0.0003
Echinococcus multilocularis 6 phosphofructokinase 0.0129 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Schistosoma mansoni serine/threonine protein kinase 0.0381 0.0302 0.2362
Loa Loa (eye worm) hypothetical protein 0.0037 0.0019 0.0162
Onchocerca volvulus 0.0037 0.002 0.0553
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0208 0.016 0.5138
Brugia malayi latrophilin 2 splice variant baaae 0.0068 0.0045 0.0514
Trypanosoma brucei protein kinase, putative 0.006 0.0039 0.0455
Leishmania major phosphatidylinositol 3-kinase, putative 0.0954 0.0774 0.212
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0021 0.006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.002 0.0147
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0208 0.016 0.5138
Toxoplasma gondii 6-phosphofructokinase 0.0035 0.0018 0.0207
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.002 0.002
Onchocerca volvulus Serine\/threonine kinase homolog 0.0227 0.0176 0.5164
Trypanosoma brucei PAB1-binding protein , putative 0.005 0.003 0.0355
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0478 0.0383 0.4426
Onchocerca volvulus 0.0032 0.0015 0.0417
Loa Loa (eye worm) voltage-dependent calcium channel beta 2a subunit 0.0212 0.0163 0.1425
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0006 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0008 0.0083
Trichomonas vaginalis PIKK family atypical protein kinase 0.0595 0.0478 0.5537
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.1014 0.0823 0.0823
Loa Loa (eye worm) phosphofructokinase 0.0129 0.0095 0.0825
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.002 0.0147
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0037 0.002 0.002
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0072 0.0048 0.0556
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0313 0.0247 0.2848
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0043
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0037 0.0019 0.1154
Loa Loa (eye worm) G-protein coupled receptor 0.0037 0.002 0.0165
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0062
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.1064 0.0864 1
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0208 0.016 0.0461
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0019 0.0005 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0954 0.0774 0.8958
Trypanosoma cruzi target of rapamycin kinase 3 0.1003 0.0814 0.2341
Trypanosoma brucei sphingolipid delta 4 desaturase, putative 0.0035 0.0017 0.0198
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0252 0.0196 0.235
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.1025 0.0832 0.2392
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Loa Loa (eye worm) hypothetical protein 0.01 0.0071 0.0617
Trypanosoma brucei fatty acid desaturase, putative 0.0427 0.034 0.4077
Toxoplasma gondii hypothetical protein 0.0063 0.0041 0.0498
Schistosoma mansoni hypothetical protein 0.0403 0.032 0.2502
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.1025 0.0832 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0037 0.002 0.0147
Leishmania major fatty acid desaturase, putative,sphingolipid delta 4 desaturase, putative 0.0035 0.0017 0.0047
Echinococcus multilocularis protein kinase shaggy 0.006 0.0039 0.0039
Trichomonas vaginalis CMGC family protein kinase 0.0162 0.0123 0.1414
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0021 0.0237
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0011 0.0079
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0552 0.0443 0.512
Loa Loa (eye worm) hypothetical protein 0.0205 0.0158 0.1375
Onchocerca volvulus 0.0208 0.016 0.4708
Plasmodium falciparum replication factor C subunit 1, putative 0.0021 0.0006 0.0159
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0037 0.002 0.002
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0208 0.016 0.016
Echinococcus granulosus bloom syndrome protein 0.0025 0.001 0.001
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0072 0.0048 0.0556
Echinococcus granulosus SAM and MBT domain containing protein 0.0048 0.0028 0.0028
Trichomonas vaginalis PIKK family atypical protein kinase 0.0954 0.0774 0.8958
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0569 0.0457 0.3575
Entamoeba histolytica protein kinase, putative 0.006 0.0039 0.0438
Entamoeba histolytica protein kinase rad3, putative 0.0552 0.0443 0.512
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0036 0.0417
Loa Loa (eye worm) hypothetical protein 0.0031 0.0015 0.012
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0015 0.0015
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0023 0.0008 0.0059
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0072 0.0048 0.0573
Plasmodium vivax ataxin-2 like protein, putative 0.005 0.003 0.0951
Trichomonas vaginalis PIKK family atypical protein kinase 0.0552 0.0443 0.5122
Trypanosoma brucei delta-4 fatty acid desaturase 0.0035 0.0017 0.0198
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0015 0.0015
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0049 0.003 0.3049
Loa Loa (eye worm) hypothetical protein 0.0048 0.0028 0.0239
Echinococcus granulosus cyclin dependent kinase 19 0.0159 0.0119 0.0119
Loa Loa (eye worm) neuropeptide F receptor 0.0037 0.002 0.0165
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0015 0.0015
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0058 0.0036 0.0312
Onchocerca volvulus 0.0037 0.002 0.0553
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0003 0.0003
Schistosoma mansoni neuropeptide receptor 0.0037 0.002 0.0147
Entamoeba histolytica hypothetical protein 0.0079 0.0054 0.062
Loa Loa (eye worm) hypothetical protein 0.0032 0.0015 0.0124
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.1025 0.0832 0.0832
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0038 0.002 0.002
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.081 0.0655 0.7586
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0023 0.0008 0.0053
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0006 0.0006
Mycobacterium tuberculosis Probable conserved membrane protein 0.0035 0.0017 0.1033
Trichomonas vaginalis CAMK family protein kinase 0.0227 0.0176 0.2032
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0023 0.0008 0.0441
Plasmodium vivax acyl-CoA synthetase, putative 0.0037 0.0019 0.0593
Schistosoma mansoni alpha-glucosidase 0.0151 0.0113 0.0879
Echinococcus multilocularis regulator of G protein signaling 7 0.0023 0.0008 0.0008
Brugia malayi regulator of G-protein signaling rgs-7 0.0023 0.0008 0.0079
Loa Loa (eye worm) G-protein coupled receptor 0.0037 0.002 0.0165
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0006 0.0054
Entamoeba histolytica serine/threonine protein kinase, putative 0.0227 0.0176 0.2028
Mycobacterium ulcerans linoleoyl-CoA desaturase, DesA3_2 0.0035 0.0017 0.1751
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.1014 0.0823 0.2366
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0611 0.0492 0.6068
Trypanosoma cruzi delta-4 fatty acid desaturase, putative 0.0035 0.0017 0.0049
Schistosoma mansoni single-minded 0.0058 0.0036 0.0278
Echinococcus granulosus histone acetyltransferase MYST2 0.0054 0.0034 0.0034
Schistosoma mansoni histamine h1 receptor 0.0037 0.002 0.0147
Echinococcus multilocularis 0.0208 0.016 0.016
Brugia malayi Regulator of G protein signaling domain containing protein 0.0023 0.0008 0.0079
Brugia malayi hypothetical protein 0.0037 0.002 0.0217
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0018 0.0198
Echinococcus multilocularis regulator of G protein signaling 7 0.0023 0.0008 0.0008
Trichomonas vaginalis casein kinase II beta chain, putative 0.0043 0.0025 0.028
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0049 0.003 0.0336
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0072 0.0048 0.0556
Echinococcus granulosus histone lysine methyltransferase setb 0.0036 0.0019 0.0019
Plasmodium vivax 6-phosphofructokinase, putative 0.0035 0.0018 0.0538
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0208 0.016 0.1249
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0208 0.016 0.016
Schistosoma mansoni hypothetical protein 0.0301 0.0236 0.1847
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0032 0.0015 0.0015
Echinococcus granulosus lamin dm0 0.0032 0.0015 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.023 0.0178 0.206
Trichomonas vaginalis adenylate cyclase, putative 0.0015 0.0001 0.0009
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0208 0.016 0.5138
Echinococcus granulosus g protein coupled receptor 0.0037 0.002 0.002
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0103 0.0073 0.0073
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0106 0.0076 0.0587
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0012 0.0128
Brugia malayi hypothetical protein 0.0037 0.002 0.0217
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0019 0.0005 0.0013
Onchocerca volvulus 0.028 0.0219 0.6439
Entamoeba histolytica hypothetical protein 0.0208 0.016 0.1849
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.1025 0.0832 0.0832
Schistosoma mansoni amine GPCR 0.0037 0.002 0.0147
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0036 0.0417
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0037 0.002 0.002
Entamoeba histolytica hypothetical protein 0.0023 0.0008 0.0079
Mycobacterium ulcerans 6-phosphofructokinase 0.0129 0.0095 1
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0072 0.0048 0.0556
Onchocerca volvulus 0.0427 0.034 1
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.006 0.0039 0.0467
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0381 0.0302 0.3492
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0072 0.0048 0.0556
Loa Loa (eye worm) mbt repeat family protein 0.0048 0.0028 0.0239
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.1025 0.0832 0.9633
Trichomonas vaginalis casein kinase II beta chain, putative 0.0043 0.0025 0.028
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.006 0.0039 0.0105
Brugia malayi SH2 domain containing protein 0.0403 0.032 0.3704
Toxoplasma gondii sphingolipid delta 4 desaturase/c-4 hydroxylase protein des2 family protein 0.0035 0.0017 0.0204
Trichomonas vaginalis PIKK family atypical protein kinase 0.0998 0.081 0.9373
Brugia malayi RE15519p 0.0037 0.002 0.0217
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0003 0.0018
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.002 0.0147
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0015 0.0001 0.0003
Echinococcus granulosus axis inhibition protein axin 0.0023 0.0008 0.0008
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0049 0.003 0.3049
Trichomonas vaginalis PIKK family atypical protein kinase 0.0982 0.0796 0.9219
Brugia malayi serine/threonine-protein kinase plk-2 0.0227 0.0176 0.2028
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0478 0.0383 0.4423
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0048 0.0556
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0043 0.0025 0.0276
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0313 0.0247 0.2156
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.003 0.0951
Loa Loa (eye worm) fatty acid desaturase 0.0035 0.0017 0.0145
Brugia malayi FAT domain containing protein 0.0403 0.032 0.37
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.1025 0.0832 0.2392
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0788 0.0637 0.7377
Echinococcus granulosus Niemann Pick C1 protein 0.0293 0.023 0.023
Leishmania major hypothetical protein, conserved 0.005 0.003 0.0083
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.002 0.002
Brugia malayi G-protein coupled receptor 0.0037 0.002 0.0217
Echinococcus multilocularis bloom syndrome protein 0.0025 0.001 0.001
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0227 0.0176 0.1535
Trypanosoma cruzi fatty acid desaturase, putative 0.0427 0.034 0.0977
Schistosoma mansoni axis inhibition protein axin 0.0023 0.0008 0.0053
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.003 0.0087
Loa Loa (eye worm) acyl-CoA desaturase 0.0392 0.0311 0.2724
Loa Loa (eye worm) hypothetical protein 0.0037 0.0019 0.0162
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0037 0.002 0.0147
Leishmania major fatty-acid desaturase, putative 0.0427 0.034 0.0931
Echinococcus multilocularis Zinc finger, PHD finger 0.0313 0.0247 0.0247
Loa Loa (eye worm) hypothetical protein 0.0809 0.0654 0.573
Schistosoma mansoni neuropeptide receptor 0.0037 0.002 0.0147
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0001 0.0005
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0017 0.0003 0.0003
Entamoeba histolytica hypothetical protein 0.0079 0.0054 0.062
Trichomonas vaginalis PIKK family atypical protein kinase 0.0998 0.081 0.9373
Echinococcus granulosus biogenic amine 5HT receptor 0.0037 0.002 0.002
Brugia malayi intermediate filament protein 0.0032 0.0015 0.0164
Echinococcus multilocularis Peptidase M, neutral zinc metallopeptidases, zinc binding site 0.0035 0.0017 0.0017
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0208 0.016 0.1973
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0208 0.016 0.1973
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0023 0.0008 0.0741
Trichomonas vaginalis PIKK family atypical protein kinase 0.0982 0.0796 0.9219
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0032 0.0015 0.0171
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.002 0.002
Brugia malayi CHD4 protein 0.0017 0.0003 0.0023
Brugia malayi mbt repeat family protein 0.0048 0.0028 0.0316
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0139 0.0103 0.0804
Trypanosoma cruzi hypothetical protein, conserved 0.4241 0.3477 1
Echinococcus granulosus neuropeptide Y receptor 0.0037 0.002 0.002
Schistosoma mansoni ankyrin 23/unc44 0.0017 0.0003 0.0016
Trichomonas vaginalis phosphofructokinase, putative 0.0129 0.0095 0.1094
Echinococcus multilocularis somatostatin receptor 0.0037 0.002 0.002
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0072 0.0048 0.0556
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1014 0.0823 0.9526
Schistosoma mansoni serine/threonine protein kinase 0.0159 0.0119 0.0929
Brugia malayi putative neuropeptide receptor 0.0037 0.002 0.0217
Brugia malayi CHE-14 protein 0.0088 0.0061 0.0701
Echinococcus granulosus nibrin 0.0021 0.0006 0.0006
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0072 0.0048 0.0556
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0032 0.0015 0.0124
Trichomonas vaginalis CMGC family protein kinase 0.0162 0.0123 0.1414
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.036 0.0285 0.082
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0005 0.0056
Echinococcus multilocularis lamin dm0 0.0032 0.0015 0.0015
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0018 0.1051
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0976 0.0792 0.9165
Echinococcus multilocularis regulator of G protein signaling 3 0.0023 0.0008 0.0008
Echinococcus granulosus allatostatin A receptor 0.0037 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0108 0.0078 0.0673
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0008 0.0083
Echinococcus granulosus casein kinase ii subunit beta 0.0043 0.0025 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0208 0.016 0.1853
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0403 0.032 0.032
Mycobacterium tuberculosis Conserved hypothetical protein 0.0208 0.016 1
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0072 0.0048 0.0048
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0967 0.0784 0.2149
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0034 0.0017 0.0017
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0021 0.0006 0.0057
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.002 0.002
Echinococcus granulosus survival motor neuron protein 1 0.0809 0.0654 0.0654
Brugia malayi putative neuropeptide receptor NPR1 0.0037 0.002 0.0217
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0027 0.0011 0.0117
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0015 0.0002 0.0002
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0208 0.016 0.016
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0569 0.0457 0.5487
Echinococcus granulosus fmrfamide receptor 0.0037 0.002 0.002
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0035 0.0018 0.0143
Schistosoma mansoni kinase 0.0117 0.0085 0.0662
Echinococcus granulosus neuropeptide receptor 0.0037 0.002 0.002
Trypanosoma cruzi polo-like protein kinase, putative 0.0227 0.0176 0.0505
Trichomonas vaginalis PIKK family atypical protein kinase 0.0569 0.0457 0.5288
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0072 0.0048 0.0556
Brugia malayi Death domain containing protein 0.0017 0.0003 0.0024
Echinococcus granulosus Fatty acid desaturase type 1 0.0035 0.0017 0.0017
Schistosoma mansoni hypothetical protein 0.0085 0.0059 0.0453
Mycobacterium leprae conserved hypothetical protein 0.0208 0.016 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0034 0.0286
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Echinococcus multilocularis SAM and MBT domain containing protein 0.0048 0.0028 0.0028
Schistosoma mansoni high voltage-activated calcium channel beta subunit 2 0.0103 0.0074 0.0569
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0139 0.0103 0.0103
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0001 0.0005
Trichomonas vaginalis casein kinase II beta chain, putative 0.0043 0.0025 0.028
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.1025 0.0832 0.228
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0079 0.0054 0.0054
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0049 0.003 0.0084
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Entamoeba histolytica protein kinase domain containing protein 0.0162 0.0123 0.141
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.1064 0.0864 0.2484
Leishmania major cytochrome p450-like protein 0.0023 0.0008 0.0021
Echinococcus multilocularis muscleblind protein 1 0.0149 0.0112 0.0112
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0532 0.0427 0.4936
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0313 0.0247 0.2957
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0205 0.0158 0.1816
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0037 0.002 0.002
Schistosoma mansoni hypothetical protein 0.0023 0.0008 0.0052
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0139 0.0103 0.0103
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0035 0.0018 0.0198
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0072 0.0048 0.0556
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0313 0.0247 0.0675
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0038 0.002 0.0152
Mycobacterium ulcerans electron transfer protein FdxB 0.0035 0.0017 0.1751
Schistosoma mansoni transcription factor LCR-F1 0.0079 0.0054 0.0419
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Loa Loa (eye worm) PXA domain-containing protein 0.0024 0.0009 0.0072
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.006 0.0039 0.0111
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0381 0.0302 0.0302
Schistosoma mansoni lamin 0.0032 0.0015 0.0111
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.0008 0.0022
Echinococcus multilocularis regulator of G protein signaling 0.0023 0.0008 0.0008
Schistosoma mansoni protein kinase 0.0162 0.0123 0.0953
Brugia malayi G protein-coupled receptor 0.0037 0.002 0.0217
Entamoeba histolytica hypothetical protein 0.0023 0.0008 0.0079
Onchocerca volvulus 0.0037 0.002 0.0553
Toxoplasma gondii CMGC kinase, CK2 family 0.0162 0.0123 0.1504
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.1064 0.0864 1
Loa Loa (eye worm) hypothetical protein 0.036 0.0285 0.2497
Schistosoma mansoni cellular tumor antigen P53 0.0059 0.0037 0.0285
Leishmania major alpha glucosidase II subunit, putative 0.0039 0.0021 0.0057
Echinococcus granulosus sex peptide receptor 0.0037 0.002 0.002
Onchocerca volvulus 0.0035 0.0017 0.0486
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0208 0.016 0.192
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.002 0.002
Schistosoma mansoni hypothetical protein 0.0068 0.0045 0.0347
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0021 0.0237
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0008 0.0083
Brugia malayi PXA domain containing protein 0.0024 0.0009 0.0095
Loa Loa (eye worm) fatty acid desaturase 0.0035 0.0017 0.0145
Echinococcus granulosus voltage dependent calcium channel 0.0038 0.002 0.002
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0083 0.0954
Trichomonas vaginalis PIKK family atypical protein kinase 0.0595 0.0478 0.5537
Echinococcus granulosus tm gpcr rhodopsin 0.0037 0.002 0.002
Echinococcus granulosus death domain containing protein 0.0017 0.0003 0.0003
Mycobacterium tuberculosis Possible electron transfer protein FdxB 0.0035 0.0017 0.1033
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0015 0.0001 0.0009
Schistosoma mansoni amine GPCR 0.0037 0.002 0.0147
Giardia lamblia Hypothetical protein 0.0208 0.016 0.1871
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0015 0.0001 0.0009
Echinococcus granulosus regulator of G protein signaling 3 0.0023 0.0008 0.0008
Brugia malayi sulfakinin receptor protein 0.0037 0.002 0.0217
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Brugia malayi hypothetical protein 0.0809 0.0654 0.757
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0208 0.016 0.5138
Echinococcus granulosus replication factor c subunit 1 0.0021 0.0006 0.0006
Toxoplasma gondii FATC domain-containing protein 0.0569 0.0457 0.5639
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Trypanosoma brucei polo-like protein kinase 0.0227 0.0176 0.2106
Trichomonas vaginalis PIKK family atypical protein kinase 0.1003 0.0814 0.9425
Brugia malayi hypothetical protein 0.0037 0.002 0.0217
Onchocerca volvulus 0.0119 0.0087 0.2536
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0006 0.0062
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0021 0.0233
Echinococcus multilocularis orexin receptor type 2 0.0037 0.002 0.002
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0008 0.0053
Trichomonas vaginalis PIKK family atypical protein kinase 0.0564 0.0453 0.5243
Echinococcus multilocularis expressed conserved protein 0.0193 0.0147 0.0147
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.002 0.002
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.0007 0.0199
Trichomonas vaginalis maltase-glucoamylase, putative 0.0039 0.0021 0.0237
Schistosoma mansoni cpg binding protein 0.0062 0.004 0.0305
Echinococcus granulosus regulator of G protein signaling 3 0.0023 0.0008 0.0008
Trichomonas vaginalis set domain proteins, putative 0.028 0.0219 0.2531
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0478 0.0383 0.4592
Onchocerca volvulus 0.0037 0.002 0.0553
Leishmania major acetyl-CoA synthetase, putative 0.0014 0.0001 0.0002
Trichomonas vaginalis replication factor C large subunit, putative 0.0021 0.0006 0.0062
Brugia malayi hypothetical protein 0.0023 0.0008 0.0079
Echinococcus multilocularis replication factor c subunit 1 0.0021 0.0006 0.0006
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0037 0.002 0.0147
Brugia malayi Csnk2b protein 0.0043 0.0025 0.0276
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.01 0.0071 0.0816
Loa Loa (eye worm) hypothetical protein 0.0149 0.0112 0.0971
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0037 0.002 0.0217
Echinococcus multilocularis serotonin receptor 0.0037 0.002 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0976 0.0792 0.9166
Trypanosoma brucei delta-6 fatty acid desaturase, putative 0.0035 0.0017 0.0198
Loa Loa (eye worm) pigment dispersing factor receptor c 0.01 0.0071 0.0617
Trichomonas vaginalis casein kinase II beta chain, putative 0.0043 0.0025 0.028
Trichomonas vaginalis casein kinase II beta chain, putative 0.0043 0.0025 0.028
Echinococcus multilocularis histone acetyltransferase MYST2 0.0054 0.0034 0.0034
Schistosoma mansoni neuropeptide receptor 0.0037 0.002 0.0147
Schistosoma mansoni chromosome transmission fidelity factor 0.0021 0.0006 0.0039
Echinococcus granulosus netrin receptor unc 5 0.0017 0.0003 0.0003
Brugia malayi intracellular kinase 0.006 0.0039 0.0438
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0072 0.0048 0.0556
Schistosoma mansoni casein kinase II beta subunit 0.0043 0.0025 0.0187
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.002 0.002
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0129 0.0095 0.1132
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0106 0.0076 0.0587
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Trypanosoma cruzi delta-4 fatty acid desaturase, putative 0.0035 0.0017 0.0049
Echinococcus multilocularis expressed conserved protein 0.0097 0.0069 0.0069
Trypanosoma brucei target of rapamycin kinase 3, putative 0.1003 0.0814 0.9785
Schistosoma mansoni ap endonuclease 0.0058 0.0036 0.0279
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.0003 0.0024
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Trichomonas vaginalis DNA helicase recq1, putative 0.0025 0.001 0.0105
Echinococcus multilocularis casein kinase ii subunit alpha 0.0162 0.0123 0.0123
Onchocerca volvulus 0.0037 0.002 0.0553
Trichomonas vaginalis PIKK family atypical protein kinase 0.0595 0.0478 0.5537
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0018 0.0198
Echinococcus multilocularis Niemann Pick C1 protein 0.0205 0.0158 0.0158
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0227 0.0176 0.0482
Echinococcus multilocularis beta adrenergic receptor kinase 0.0027 0.0011 0.0011
Toxoplasma gondii phosphofructokinase PFKII 0.0035 0.0018 0.0207
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0015 0.0001 0.0003
Plasmodium vivax hypothetical protein, conserved 0.0208 0.016 0.5138
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0001 0.0009
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0199 0.0153 0.0153
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0226 0.0175 0.0502
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0059
Loa Loa (eye worm) phosphatidylinositol kinase 0.0208 0.016 0.14
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0015 0.0001 0.0001
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0072 0.0048 0.0556
Plasmodium vivax casein kinase II beta chain, putative 0.0043 0.0025 0.0767
Brugia malayi hypothetical protein 0.0156 0.0117 0.1349
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0037 0.0019 1
Echinococcus multilocularis neuropeptide receptor 0.0037 0.002 0.002
Brugia malayi Voltage-dependent L-type calcium channel beta-2 subunit 0.0212 0.0163 0.1882
Schistosoma mansoni 6-phosphofructokinase 0.0129 0.0095 0.0737
Loa Loa (eye worm) oxidoreductase 0.0014 0.0001 0.0000081462
Schistosoma mansoni patched 1 0.0088 0.0061 0.0474
Trichomonas vaginalis PIKK family atypical protein kinase 0.0954 0.0774 0.8958
Echinococcus multilocularis G-protein coupled receptor, putative 0.0037 0.002 0.002
Schistosoma mansoni growth hormone secretagogue receptor 0.0037 0.002 0.0147
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0008 0.0086
Brugia malayi hypothetical protein 0.0037 0.002 0.0217
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0001 0.0005
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0021 0.0006 0.0062
Giardia lamblia Kinase, CMGC CK2 0.0162 0.0123 0.1412
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0012 0.0128
Brugia malayi topoisomerase 0.0021 0.0006 0.0057
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0313 0.0247 0.0247
Trypanosoma cruzi fatty acid desaturase, putative 0.0035 0.0017 0.0049
Trichomonas vaginalis CAMK family protein kinase 0.0227 0.0176 0.2032
Schistosoma mansoni hypothetical protein 0.0032 0.0015 0.0111
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Loa Loa (eye worm) hypothetical protein 0.0022 0.0007 0.0052
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0014 0.0001 0.0002
Schistosoma mansoni neuropeptide receptor 0.0037 0.002 0.0147
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0021 0.0006 0.0062
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.003 0.3049
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0037 0.002 0.0165
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0054 0.0034 0.0034
Loa Loa (eye worm) 6-phosphofructokinase 0.0129 0.0095 0.0825
Echinococcus multilocularis GPCR, family 2 0.0032 0.0015 0.0015
Trichomonas vaginalis CMGC family protein kinase 0.006 0.0039 0.0442
Echinococcus granulosus single minded 2 0.0043 0.0024 0.0024
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0032 0.0015 0.0171
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0139 0.0103 0.0103
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0072 0.0048 0.0556
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0313 0.0247 0.2851
Trichomonas vaginalis PIKK family atypical protein kinase 0.0343 0.0271 0.3136
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0038 0.002 0.002
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0129 0.0095 0.5896
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.005 0.003 0.0228
Schistosoma mansoni aryl hydrocarbon receptor 0.0058 0.0036 0.0278
Echinococcus granulosus axis inhibition protein axin 0.0023 0.0008 0.0008
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0129 0.0095 0.5896
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0006 0.0016
Leishmania major delta-4 fatty acid desaturase 0.0035 0.0017 0.0047
Echinococcus granulosus peptide allatostatin:somatostatin 0.0037 0.002 0.002
Echinococcus granulosus intermediate filament protein 0.0032 0.0015 0.0015
Brugia malayi hypothetical protein 0.0037 0.002 0.0217
Brugia malayi neuropeptide F receptor 0.0037 0.002 0.0217
Echinococcus multilocularis lamin 0.0032 0.0015 0.0015
Echinococcus multilocularis dro:myosuppressin receptor 0.0037 0.002 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0001 0.0009
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0037 0.002 0.0147
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.0003 0.0024
Brugia malayi A-kinase anchor protein 10, precursor 0.0023 0.0008 0.0079
Brugia malayi Intermediate filament tail domain containing protein 0.0032 0.0015 0.0164
Brugia malayi CXXC zinc finger family protein 0.0062 0.004 0.0451
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0313 0.0247 0.2851
Loa Loa (eye worm) hypothetical protein 0.0194 0.0148 0.1292
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.003 0.0087
Plasmodium vivax 6-phosphofructokinase, putative 0.0035 0.0018 0.0538
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0019 0.0005 0.0013
Schistosoma mansoni alpha glucosidase 0.0039 0.0021 0.0157
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0037 0.002 0.0147
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0017 0.0003 0.0003
Trichomonas vaginalis DNA helicase recq, putative 0.0025 0.001 0.0105
Leishmania major hypothetical protein, unknown function 0.0208 0.016 0.0439
Onchocerca volvulus 0.0037 0.002 0.0553
Loa Loa (eye worm) phosphatidylinositol 3 0.0208 0.016 0.14
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0003 0.0003
Echinococcus multilocularis protein dispatched 1 0.01 0.0072 0.0072
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0037 0.002 0.002
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0175 0.0133 0.116
Schistosoma mansoni biogenic amine receptor 0.0037 0.002 0.0147
Trypanosoma brucei cytochrome b5-dependent oleate desaturase 0.0035 0.0017 0.0198
Echinococcus multilocularis lysosomal alpha glucosidase 0.0175 0.0133 0.0133
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0246 0.0191 0.167
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 1.2172 1 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.002 0.017
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0036 0.1145
Entamoeba histolytica hypothetical protein 0.0079 0.0054 0.062
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0037 0.002 0.0553
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0006 0.0062
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0015 0.0001 0.0009
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0021 0.0237
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.1025 0.0832 1
Plasmodium falciparum glycogen synthase kinase 3 0.006 0.0039 0.1217
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Loa Loa (eye worm) CYP4Cod1 0.0023 0.0008 0.0061
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0165 0.0125 0.1434
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0058 0.0036 0.2229
Entamoeba histolytica hypothetical protein 0.0079 0.0054 0.062
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Entamoeba histolytica hypothetical protein 0.0208 0.016 0.1849
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Echinococcus granulosus regulator of G protein signaling 7 0.0023 0.0008 0.0008
Trichomonas vaginalis maltase-glucoamylase, putative 0.0014 0.0001 0.0005
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0008 0.0053
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Onchocerca volvulus 0.0032 0.0015 0.0417
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0313 0.0247 0.3039
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1025 0.0832 0.9633
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0049 0.003 0.3049
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.003 0.008
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0043
Onchocerca volvulus 0.0037 0.002 0.0553
Schistosoma mansoni fkbp-rapamycin associated protein 0.0552 0.0443 0.3463
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0017 0.0003 0.0003
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0058 0.0036 0.0036
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.1566 0.1277 1
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0037 0.002 0.002
Leishmania major delta-6 fatty acid desaturase 0.0035 0.0017 0.0047
Schistosoma mansoni fatty acid desaturase 0.0035 0.0017 0.0129
Onchocerca volvulus 0.0208 0.016 0.4708
Echinococcus multilocularis rhodopsin orphan GPCR 0.0037 0.002 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0976 0.0792 0.9165
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0478 0.0383 0.4426
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.002 0.002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0019 0.0141
Echinococcus multilocularis musashi 0.0032 0.0015 0.0015
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0072 0.0048 0.0556
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0041 0.0471
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0027 0.0011 0.0088
Echinococcus multilocularis neuropeptide Y receptor 0.0037 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Echinococcus granulosus expressed conserved protein 0.0097 0.0069 0.0069
Echinococcus multilocularis Ankyrin 0.0017 0.0003 0.0003
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.1025 0.0832 0.6515
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0552 0.0443 0.0443
Echinococcus multilocularis Regulator of G protein signaling 20 0.0023 0.0008 0.0008
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0011 0.0079
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0001 0.0002
Schistosoma mansoni hypothetical protein 0.0208 0.016 0.1251
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Echinococcus multilocularis cpg binding protein 0.0065 0.0043 0.0043
Schistosoma mansoni z-protein (S1r protein) 0.0023 0.0008 0.0053
Echinococcus multilocularis Niemann Pick C1 protein 0.0293 0.023 0.023
Mycobacterium ulcerans putative regulatory protein 0.0023 0.0008 0.0748
Trichomonas vaginalis conserved hypothetical protein 0.0403 0.032 0.3703
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0083 0.0954
Echinococcus multilocularis tumor protein p63 0.0401 0.0318 0.0318
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0208 0.016 0.0461
Loa Loa (eye worm) hypothetical protein 0.0035 0.0017 0.0145
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0569 0.0457 0.1314
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0017 0.0003 0.0065
Entamoeba histolytica hypothetical protein 0.0021 0.0006 0.0057
Echinococcus multilocularis axis inhibition protein axin 0.0023 0.0008 0.0008
Echinococcus multilocularis dnaJ subfamily B 0.0472 0.0377 0.0377
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.1064 0.0864 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0037 0.002 0.002
Onchocerca volvulus 0.0049 0.003 0.0847
Mycobacterium tuberculosis Probable transmembrane alkane 1-monooxygenase AlkB (alkane 1-hydroxylase) (lauric acid omega-hydroxylase) (omega-hydroxylase) (f 0.0035 0.0017 0.1033
Toxoplasma gondii hypothetical protein 0.0023 0.0008 0.0087
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0023 0.0008 0.0008
Loa Loa (eye worm) 6-phosphofructokinase 0.0129 0.0095 0.0825
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0048 0.0028 0.0803
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0023 0.0008 0.0008
Echinococcus multilocularis axis inhibition protein axin 0.0023 0.0008 0.0008
Echinococcus granulosus neuropeptide receptor 0.0037 0.002 0.002
Trypanosoma cruzi cytochrome b5-dependent oleate desaturase 0.0035 0.0017 0.0049
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0006 0.0016
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0072 0.0048 0.0139
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0037 0.002 0.0217
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0478 0.0383 0.4426
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0015 0.0001 0.0003
Schistosoma mansoni biogenic amine (5HT) receptor 0.0037 0.002 0.0147
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0072 0.0048 0.0556
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0001 0.0000081462
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0037 0.002 0.0147
Schistosoma mansoni netrin receptor unc5 0.0017 0.0003 0.0016
Entamoeba histolytica protein kinase domain containing protein 0.006 0.0039 0.0438
Schistosoma mansoni opsin-like receptor 0.0037 0.002 0.0147
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0021 0.0233
Brugia malayi Niemann-Pick C1 protein precursor 0.0205 0.0158 0.1816
Echinococcus granulosus tachykinin peptides receptor 99D 0.0037 0.002 0.002
Loa Loa (eye worm) phosphatidylinositol 3 0.14 0.1141 1
Brugia malayi phosphofructokinase 0.0129 0.0095 0.109
Loa Loa (eye worm) hypothetical protein 0.0156 0.0117 0.1021
Onchocerca volvulus 0.0101 0.0072 0.2108
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0037 0.002 0.002
Brugia malayi Cytochrome P450 family protein 0.0023 0.0008 0.0081
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0139 0.0103 0.0899
Trichomonas vaginalis casein kinase II beta chain, putative 0.0043 0.0025 0.028
Loa Loa (eye worm) follicle stimulating hormone receptor 0.031 0.0244 0.2132
Giardia lamblia Casein kinase II beta chain 0.0043 0.0025 0.0228
Brugia malayi hypothetical protein 0.005 0.003 0.0342
Schistosoma mansoni neuropeptide F-like receptor 0.0037 0.002 0.0147
Trichomonas vaginalis PIKK family atypical protein kinase 0.1025 0.0832 0.9633
Brugia malayi Glycosyl hydrolases family 31 protein 0.0039 0.0021 0.0233
Echinococcus multilocularis protein patched 0.0088 0.0061 0.0061
Onchocerca volvulus 0.006 0.0039 0.1115
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0008 0.0053
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0015 0.0001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0313 0.0247 0.2848
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0018 0.1051
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0208 0.016 0.016
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0208 0.016 0.1849
Schistosoma mansoni amine GPCR 0.0037 0.002 0.0147
Brugia malayi Pax transcription activation domain interacting protein 0.0021 0.0006 0.0057
Schistosoma mansoni blooms syndrome DNA helicase 0.002 0.0005 0.0034
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0072 0.0048 0.0556
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0072 0.0048 0.0556
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0072 0.0048 0.0556
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0023 0.0008 0.0083
Entamoeba histolytica hypothetical protein 0.0898 0.0728 0.8425
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0037 0.002 0.0147
Echinococcus granulosus neuropeptide s receptor 0.0037 0.002 0.002
Loa Loa (eye worm) TYRA-2 protein 0.0037 0.002 0.0165
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0208 0.016 0.1849
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0036 0.0019 0.0223
Loa Loa (eye worm) neuropeptide F receptor 0.0037 0.002 0.0165
Brugia malayi hypothetical protein 0.0021 0.0006 0.0057
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0054 0.0034 0.0378
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.1014 0.0823 0.6443
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0008 0.0083
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0038 0.002 0.002
Brugia malayi hypothetical protein 0.0037 0.002 0.0217
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0072 0.0048 0.0556
Echinococcus granulosus g-protein coupled receptor 0.0037 0.002 0.002
Plasmodium vivax replication factor C subunit 1, putative 0.0021 0.0006 0.0159
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0049 0.003 0.0336
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.081 0.0655 0.7586
Brugia malayi Pre-SET motif family protein 0.0036 0.0019 0.0209
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.4207 0.3449 0.3449
Loa Loa (eye worm) hypothetical protein 0.0049 0.003 0.0252
Entamoeba histolytica phosphofructokinase, putative 0.0129 0.0095 0.109
Echinococcus multilocularis survival motor neuron protein 1 0.0809 0.0654 0.0654
Echinococcus granulosus rhodopsin orphan GPCR 0.0037 0.002 0.002
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0037 0.002 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0998 0.081 0.9373
Leishmania major phosphatidylinositol 3-kinase, putative 0.0313 0.0247 0.0675
Onchocerca volvulus 0.0037 0.002 0.0553
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0059
Loa Loa (eye worm) hypoxia-induced factor 1 0.0179 0.0136 0.1184
Brugia malayi hypothetical protein 0.0037 0.002 0.0217
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0535 0.0429 0.3356
Schistosoma mansoni serine/threonine protein kinase 0.0227 0.0176 0.1372
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0208 0.016 0.1853
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0038 0.002 0.002
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0208 0.016 0.0461
Brugia malayi hypothetical protein 0.0033 0.0016 0.0172
Loa Loa (eye worm) hypothetical protein 0.0119 0.0087 0.0755
Entamoeba histolytica casein kinase, putative 0.0162 0.0123 0.141
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0058 0.0036 0.0104
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0058 0.0036 0.3781
Trichomonas vaginalis PIKK family atypical protein kinase 0.0976 0.0792 0.9166
Schistosoma mansoni hypothetical protein 0.0097 0.0069 0.053
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.1003 0.0814 0.2231
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0313 0.0247 0.7914
Schistosoma mansoni myelin transcription factor 1 myt1 0.0054 0.0034 0.0256
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0058 0.0036 0.0428
Onchocerca volvulus 0.0037 0.002 0.0553
Schistosoma mansoni hypothetical protein 0.0037 0.002 0.0147
Mycobacterium ulcerans hypothetical protein 0.0035 0.0017 0.1751
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0552 0.0443 0.0443
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0037 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0023 0.0008 0.0059
Trichomonas vaginalis phosphofructokinase, putative 0.0129 0.0095 0.1094
Brugia malayi Muscleblind-like protein 0.0149 0.0112 0.1282
Brugia malayi neuropeptide F receptor 0.0037 0.002 0.0217
Plasmodium vivax hypothetical protein 0.0208 0.016 0.5138
Schistosoma mansoni hypothetical protein 0.0085 0.0059 0.0453
Entamoeba histolytica hypothetical protein 0.0569 0.0457 0.5285
Loa Loa (eye worm) hypothetical protein 0.0786 0.0635 0.5564
Onchocerca volvulus 0.0165 0.0125 0.3651
Brugia malayi Pre-SET motif family protein 0.0246 0.0191 0.2206
Onchocerca volvulus 0.0156 0.0117 0.3434
Echinococcus granulosus somatostatin receptor 0.0037 0.002 0.002
Plasmodium vivax SET domain protein, putative 0.0036 0.0019 0.0581
Brugia malayi Melatonin receptor type 1A 0.0037 0.002 0.0217
Schistosoma mansoni voltage-gated cation channel 0.0038 0.002 0.0152
Echinococcus multilocularis serotonin receptor 0.0037 0.002 0.002
Trypanosoma brucei cytochrome P450, putative 0.0023 0.0008 0.0084
Onchocerca volvulus 0.0037 0.002 0.0553
Loa Loa (eye worm) hypothetical protein 0.0036 0.0019 0.0158
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0569 0.0457 0.5285
Giardia lamblia GTOR 0.1025 0.0832 1
Echinococcus granulosus 7TM GPCR rhodopsin 0.0037 0.002 0.002
Leishmania major glycosyl hydrolase-like protein 0.0014 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0403 0.032 0.2801
Onchocerca volvulus Neuropeptide F receptor homolog 0.0037 0.002 0.0553
Trichomonas vaginalis phosphofructokinase, putative 0.0129 0.0095 0.1094
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0043
Brugia malayi regulator of G-protein signaling egl-10 0.0023 0.0008 0.0079
Echinococcus multilocularis g protein coupled receptor 0.0037 0.002 0.002
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0027 0.0011 0.0088
Brugia malayi PAS domain containing protein 0.0058 0.0036 0.0412
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0001 0.0005
Plasmodium vivax casein kinase II beta chain, putative 0.0043 0.0025 0.0767
Leishmania major phosphatidylinositol kinase related protein, putative 0.0226 0.0175 0.0478
Brugia malayi larval opioid receptor 0.0037 0.002 0.0217
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0132 0.0098 0.076
Entamoeba histolytica protein kinase domain containing protein 0.006 0.0039 0.0438
Mycobacterium ulcerans linoleoyl-CoA desaturase, DesA3 0.0035 0.0017 0.1751
Brugia malayi acyl-CoA desaturase 0.0392 0.0311 0.3599
Loa Loa (eye worm) hypothetical protein 0.0037 0.002 0.0165
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0043
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0374 0.0296 0.3516
Brugia malayi GnHR receptor homolog 0.0037 0.002 0.0217
Loa Loa (eye worm) hypothetical protein 0.0119 0.0087 0.0754
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0038 0.002 0.002
Trichomonas vaginalis CMGC family protein kinase 0.0162 0.0123 0.1414
Brugia malayi AKH receptor 0.0037 0.002 0.0217
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0898 0.0728 0.8425
Onchocerca volvulus 0.0037 0.002 0.0553
Brugia malayi hypoxia-induced factor 1 0.0179 0.0136 0.1564
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.0008 0.0022
Echinococcus granulosus 6 phosphofructokinase 0.0129 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0000081462
Trichomonas vaginalis CAMK family protein kinase 0.0227 0.0176 0.2032
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0208 0.016 0.5138
Loa Loa (eye worm) CHromoDomain protein family member 0.0017 0.0003 0.0018
Leishmania major protein kinase, putative 0.0019 0.0005 0.0012
Leishmania major protein kinase, putative 0.0019 0.0005 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0006 0.0066

Activities

Activity type Activity value Assay description Source Reference
Concentration (functional) = 0.5 ug ml-1 Minimum fungicidal concentration of the compound against Candida albicans MY 1055 ChEMBL. 1732529
Concentration (functional) = 0.5 ug ml-1 Minimum fungicidal concentration of the compound against Candida albicans MY 1028 ChEMBL. 1732529
ED50 (functional) = 7.6 mg kg-1 In vivo antifungal activity administered intraperitoneally against Candida albicans infections in mice. ChEMBL. 7650681
ED50 (functional) > 400 mg kg-1 In vivo antifungal activity administered orally against Candida albicans infections in mice. ChEMBL. 7650681
ED50 (functional) = 5 ug ml-1 In vivo effective dose for antifungal activity on sc administration in female mice infected with 2.5*10e6 cells/mL of Candida albicans at day 10 ChEMBL. 11212120
ED50 (functional) > 10 ug ml-1 In vivo effective dose for antifungal activity on sc administration in female mice infected with 2.5*10e6 cells/mL of Candida albicans at day 14 ChEMBL. 11212120
IC50 (functional) = 0.24 ug ml-1 In vitro antifungal activity against Candida albicans FP582 at 37 degrees C for 22h ChEMBL. 11212120
IC50 (functional) = 0.36 ug ml-1 In vitro inhibitory concentration required for antifungal activity against Candida albicans FP578 at 37 degrees C for 22h ChEMBL. 11212120
IC50 (functional) = 0.39 ug ml-1 In vitro antifungal activity against Candida albicans FP633 at 37 degrees C for 22h ChEMBL. 11212120
IC50 (functional) = 0.47 ug ml-1 In vitro antifungal activity against Candida albicans FP629 at 37 degrees C for 22h ChEMBL. 11212120
IC50 (functional) > 2.5 ug ml-1 In vitro inhibitory concentration degrees C for 48 hr ChEMBL. 11212120
IC50 (functional) = 1 uM Concentration of the compound inhibiting Candida beta-1,3-glucan synthesis was determined in a Candida albicans cell culture ChEMBL. 1495015
Inhibition (binding) = 76 % In vitro inhibition of glucan synthase obtained from C. albicans at a concentration of 10 ug/mL. ChEMBL. 7650681
LC30 (functional) > 500 Lytic concentration for hemolytic activity in human by akaishi method ChEMBL. 11212120
MED99 (functional) = 3 MKP Minimum effect dose required to reduce the number of colony forming units in per gram kidney of mice after being challenged, by tail vein injection, with 5 X l0e4 cells of C. albicans (MY 1055) ChEMBL. 1732529
MFC (functional) = 0.5 ug ml-1 Antifungal activity of the compound on Candida albicans MY1055. ChEMBL. 1495015
MFC (functional) = 0.5 ug ml-1 Antifungal activity of the compound on Candida albicans MY1028. ChEMBL. 1495015
MFC (functional) = 2 ug ml-1 Antifungal activity of the compound on Candida albicans MY1208. ChEMBL. 1495015
MIC (functional) = 0.312 ug ml-1 Antifungal activity against Candida albicans ChEMBL. 7650681
MLC (functional) > 500 Minimum lytic concentration that lysed red blood cells in mouse ChEMBL. 11212120
MLC (functional) > 1000 Minimum lytic concentration that lysed red blood cells in human ChEMBL. 11212120

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Candida albicans ChEMBL23 11212120
Cryptococcus neoformans ChEMBL23 11212120

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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