Detailed information for compound 1761225

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1571.1 | Formula: C68H50O44
  • H donors: 24 H acceptors: 32 LogP: 3.24 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 4
  • SMILES: OC[C@H]1O[C@H]2OC(=O)c3cc(O)c(c(c3)Oc3c(cc(c(c3O)O)O)C(=O)O[C@H]3[C@H](OC(=O)c4cc(c(Oc5c(C(=O)O[C@@H]2[C@H]([C@@H]1O)OC(=O)c1cc(O)c(c(c1)O)O)cc(O)c(c5O)O)c(O)c4)O)O[C@H]1[C@H]([C@@H]3OC(=O)c2cc(O)c(c(c2)O)O)OC(=O)c2cc(O)c(c(c2c2c(C(=O)OC1)cc(c(c2O)O)O)O)O)O
  • InChi: 1S/C68H50O44/c69-13-35-46(88)55(107-59(93)15-1-23(70)39(81)24(71)2-15)57-67(103-35)112-62(96)18-5-27(74)41(83)34(8-18)102-51-21(11-30(77)44(86)49(51)91)65(99)110-58-56(108-60(94)16-3-25(72)40(82)26(73)4-16)54-36(14-101-63(97)19-9-28(75)42(84)47(89)37(19)38-20(64(98)106-54)10-29(76)43(85)48(38)90)104-68(58)111-61(95)17-6-32(79)53(33(80)7-17)105-52-22(66(100)109-57)12-31(78)45(87)50(52)92/h1-12,35-36,46,54-58,67-92H,13-14H2/t35-,36-,46-,54-,55+,56+,57-,58-,67+,68+/m1/s1
  • InChiKey: PFUDAMHTVMSQNA-WXZXAZFGSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Probable hydrolase 0.0143 0.0785 0.1341
Loa Loa (eye worm) AGC/PKN protein kinase 0.0088 0.0443 0.0625
Brugia malayi Death domain containing protein 0.0031 0.0081 0.0114
Schistosoma mansoni serine/threonine protein kinase 0.0319 0.1895 0.2592
Leishmania major cathepsin L-like protease 0.0081 0.0399 0.3935
Trypanosoma cruzi PAB1-binding protein , putative 0.0074 0.0352 0.1319
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0123 0.0661 0.0659
Loa Loa (eye worm) hypothetical protein 0.0227 0.1318 0.1858
Plasmodium vivax importin-beta 2, putative 0.0028 0.0063 0.078
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0114 0.057
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0072 0.0265
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0042 0.0152 0.0207
Entamoeba histolytica diacylglycerol kinase, putative 0.008 0.0393 0.2274
Loa Loa (eye worm) MH2 domain-containing protein 0.0475 0.2878 0.4059
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0032 0.0086 0.0116
Schistosoma mansoni neuropeptide receptor 0.0057 0.0244 0.0332
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0016 0.0019
Entamoeba histolytica cysteine protease, putative 0.0032 0.0086 0.0491
Echinococcus granulosus Ankyrin 0.0031 0.0082 0.0109
Echinococcus granulosus epidermal growth factor receptor 0.0323 0.1919 0.2625
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0057 0.0244 0.0343
Brugia malayi hypothetical protein 0.0048 0.0187 0.0264
Echinococcus granulosus histone deacetylase 0.0042 0.0151 0.0204
Schistosoma mansoni smad1 5 8 and 0.0032 0.0091 0.0123
Entamoeba histolytica cysteine protease, putative 0.0032 0.0086 0.0491
Brugia malayi hypothetical protein 0.0057 0.0244 0.0343
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0016 0.0087
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0088 0.0443 0.0625
Plasmodium falciparum transporter, putative 0.003 0.0074 0.1727
Echinococcus granulosus rhodopsin orphan GPCR 0.0057 0.0244 0.033
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0032 0.0086 0.0409
Echinococcus multilocularis epidermal growth factor receptor 0.0174 0.0979 0.0977
Brugia malayi Histone deacetylase family protein 0.0042 0.0151 0.0213
Brugia malayi G protein-coupled receptor 0.0057 0.0244 0.0343
Trichomonas vaginalis mercuric reductase, putative 0.0029 0.0072 0.0326
Entamoeba histolytica cysteine protease, putative 0.0032 0.0086 0.0491
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0399 0.2246
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0042 0.0152 0.1927
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0073 0.035 0.444
Plasmodium falciparum serine repeat antigen 4 0.0032 0.0086 0.2021
Loa Loa (eye worm) hypothetical protein 0.0232 0.1349 0.1902
Loa Loa (eye worm) transcription factor SMAD2 0.0475 0.2878 0.4059
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0141 0.138
Onchocerca volvulus 0.0081 0.0399 0.1214
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0057 0.0244 0.0241
Schistosoma mansoni hypothetical protein 0.008 0.0393 0.0535
Onchocerca volvulus 0.0081 0.0399 0.1214
Brugia malayi hypothetical protein 0.0057 0.0244 0.0343
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.035 0.3444
Loa Loa (eye worm) hypothetical protein 0.0414 0.249 0.3511
Echinococcus multilocularis rhodopsin orphan GPCR 0.0057 0.0244 0.0241
Echinococcus granulosus neuropeptide receptor A26 0.0057 0.0244 0.033
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0343 0.2045 0.2883
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0081 0.0399 0.2246
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0032 0.0086 0.1079
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0016 0.0023
Loa Loa (eye worm) inositol-1 0.0073 0.035 0.0493
Brugia malayi MH2 domain containing protein 0.0032 0.0091 0.0128
Schistosoma mansoni cpg binding protein 0.0059 0.0257 0.035
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0062 0.0278 0.1042
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0032 0.0086 0.0116
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0016 0.0147
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0081 0.0399 0.2246
Giardia lamblia Hypothetical protein 0.0032 0.0086 0.0492
Brugia malayi Importin beta-1 subunit 0.0028 0.0063 0.0088
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0204 0.1171 0.1652
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0032 0.0086 0.0319
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0057 0.0244 0.0332
Echinococcus multilocularis histone deacetylase 6 0.0042 0.0151 0.0149
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0123 0.0661 0.6528
Leishmania major hypothetical protein, conserved 0.0074 0.0352 0.3464
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0032 0.0086 0.0409
Brugia malayi Papain family cysteine protease containing protein 0.0032 0.0086 0.0121
Echinococcus multilocularis apoptotic protease activating factor 1 0.0124 0.0665 0.0663
Echinococcus granulosus 7TM GPCR rhodopsin 0.0057 0.0244 0.033
Schistosoma mansoni tyrosine kinase 0.0174 0.0979 0.1338
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.003 0.0074 0.0098
Echinococcus granulosus neuropeptides capa receptor 0.0057 0.0244 0.033
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Plasmodium falciparum cysteine proteinase falcipain 1 0.0032 0.0086 0.2021
Entamoeba histolytica cysteine proteinase, putative 0.0081 0.0399 0.2313
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0057 0.0244 0.0241
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0179 0.1012 0.1384
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0033 0.0095 0.0928
Onchocerca volvulus 0.0147 0.0812 0.2496
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0034 0.01 0.0141
Loa Loa (eye worm) hypothetical protein 0.003 0.0074 0.0104
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0032 0.0086 0.0409
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0399 0.2246
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0036 0.0051
Onchocerca volvulus 0.0057 0.0244 0.0732
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0031 0.0081 0.0108
Entamoeba histolytica hypothetical protein 0.0036 0.0112 0.0642
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0063 0.0605
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.01 0.0141
Brugia malayi Cathepsin L-like precursor 0.0081 0.0399 0.0563
Schistosoma mansoni rac gtpase activating protein 0.008 0.0393 0.0535
Entamoeba histolytica diacylglycerol kinase, putative 0.008 0.0393 0.2274
Loa Loa (eye worm) thioredoxin reductase 0.0085 0.042 0.0592
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0036 0.0442
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0057 0.0244 0.0241
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0291 0.1721 1
Echinococcus granulosus microtubule associated protein 2 0.0678 0.4155 0.5686
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.003 0.0074 0.0099
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0143 0.0785 0.1073
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0114 0.0111
Echinococcus granulosus cathepsin b 0.044 0.2655 0.3633
Giardia lamblia Cathepsin B precursor 0.0032 0.0086 0.0492
Loa Loa (eye worm) hypothetical protein 0.0032 0.0086 0.0121
Echinococcus granulosus neuropeptide receptor 0.0057 0.0244 0.033
Entamoeba histolytica cysteine proteinase, putative 0.0081 0.0399 0.2313
Schistosoma mansoni alpha glucosidase 0.0036 0.0114 0.0153
Brugia malayi hypothetical protein 0.0057 0.0244 0.0343
Schistosoma mansoni serine/threonine protein kinase 0.0083 0.0408 0.0557
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0057 0.0244 0.0332
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Schistosoma mansoni tyrosine kinase 0.0323 0.1919 0.2626
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0032 0.0086 0.0491
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0041 0.0147 0.1442
Loa Loa (eye worm) hypothetical protein 0.0143 0.0785 0.1108
Trypanosoma cruzi cysteine peptidase, putative 0.0032 0.0086 0.0319
Schistosoma mansoni hypothetical protein 0.0057 0.0244 0.0332
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0029 0.0077
Echinococcus multilocularis dna polymerase kappa 0.0058 0.0255 0.0253
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0011
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0031 0.0082 0.011
Loa Loa (eye worm) hypothetical protein 0.06 0.3663 0.5166
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0057 0.0244 0.0332
Toxoplasma gondii thioredoxin reductase 0.0085 0.042 0.414
Echinococcus multilocularis hedgehog 0.0209 0.1204 0.1202
Giardia lamblia Cathepsin B precursor 0.0032 0.0086 0.0492
Giardia lamblia Proteasome subunit beta type 2 0.0038 0.0129 0.0744
Echinococcus granulosus fmrfamide receptor 0.0057 0.0244 0.033
Brugia malayi diacylglycerol kinase 0.008 0.0393 0.0554
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Echinococcus granulosus p2X purinoceptor 4 0.0134 0.0727 0.0993
Brugia malayi Cathepsin L-like precursor 0.0081 0.0399 0.0563
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0081 0.0399 0.0397
Brugia malayi Subtilase family protein 0.0272 0.1596 0.2251
Trichomonas vaginalis rotamase, putative 0.0034 0.01 0.0493
Echinococcus granulosus importin subunit beta 1 0.0028 0.0063 0.0083
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0364 0.2177 0.2977
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.003 0.0074 0.0104
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0179 0.1012 0.101
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0072 0.0265
Brugia malayi Proteasome A-type and B-type family protein 0.008 0.039 0.055
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.008 0.0393 0.0535
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0057 0.0244 0.0332
Schistosoma mansoni neuropeptide F-like receptor 0.0057 0.0244 0.0332
Loa Loa (eye worm) RNA binding protein 0.0064 0.0288 0.0407
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0114 0.057
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Echinococcus multilocularis dnaJ subfamily B 0.0791 0.4867 0.4866
Onchocerca volvulus 0.0081 0.0399 0.1214
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.008 0.0393 0.0535
Trypanosoma brucei trypanothione reductase 0.0085 0.042 0.414
Mycobacterium tuberculosis Conserved protein 0.0143 0.0785 0.1341
Schistosoma mansoni sodium-dependent amino acid transporter 0.003 0.0074 0.0099
Loa Loa (eye worm) TK/INSR protein kinase 0.0103 0.0537 0.0757
Loa Loa (eye worm) hypothetical protein 0.0032 0.0086 0.0121
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.1721 1
Schistosoma mansoni hypothetical protein 0.0034 0.01 0.0135
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Brugia malayi Furin-like cysteine rich region family protein 0.0323 0.1919 0.2707
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0032 0.0086 0.0492
Schistosoma mansoni neuropeptide receptor 0.0057 0.0244 0.0332
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.008 0.039 0.226
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0179 0.1012 1
Schistosoma mansoni alpha-1 adrenergic receptor 0.0057 0.0244 0.0332
Plasmodium falciparum importin beta, putative 0.0028 0.0063 0.1462
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.003 0.0074 0.0099
Loa Loa (eye worm) CXXC zinc finger family protein 0.0056 0.0237 0.0334
Loa Loa (eye worm) hypothetical protein 0.06 0.3663 0.5166
Loa Loa (eye worm) hypothetical protein 0.0143 0.0785 0.1108
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0032 0.0086 0.0492
Schistosoma mansoni polycystin 1-related 0.0019 0.0007 0.0008
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0057 0.0244 0.033
Plasmodium vivax ataxin-2 like protein, putative 0.0074 0.0352 0.4465
Trichomonas vaginalis AGC family protein kinase 0.0093 0.0474 0.2686
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0364 0.2177 0.3069
Plasmodium falciparum serine repeat antigen 9 0.0032 0.0086 0.2021
Echinococcus multilocularis orexin receptor type 2 0.0057 0.0244 0.0241
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0399 0.2246
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0032 0.0086 0.0116
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0036 0.0343
Brugia malayi ImpB/MucB/SamB family protein 0.0058 0.0255 0.036
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0143 0.0785 0.1073
Leishmania major oligopeptidase b 0.0042 0.0152 0.1495
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.1721 1
Echinococcus granulosus inhibitor of apoptosis protein 0.0483 0.2928 0.4006
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0141 0.138
Echinococcus multilocularis myotubularin protein 13 0.0085 0.0424 0.0422
Brugia malayi CXXC zinc finger family protein 0.0056 0.0237 0.0334
Echinococcus multilocularis somatostatin receptor 0.0057 0.0244 0.0241
Brugia malayi ImpB/MucB/SamB family protein 0.0058 0.0255 0.036
Echinococcus multilocularis g protein coupled receptor 0.0057 0.0244 0.0241
Trypanosoma cruzi hypothetical protein, conserved 0.0143 0.0785 0.2954
Echinococcus multilocularis sex peptide receptor 0.0057 0.0244 0.0241
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0215 0.1238 1
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0083 0.0408 0.0406
Echinococcus multilocularis g protein coupled receptor 0.0057 0.0244 0.0241
Brugia malayi neuropeptide F receptor 0.0057 0.0244 0.0343
Trypanosoma cruzi hypothetical protein, conserved 0.0143 0.0785 0.2954
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Echinococcus granulosus mothers against decapentaplegic 5 0.0032 0.0091 0.0122
Brugia malayi Pre-SET motif family protein 0.0204 0.1171 0.1652
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0042 0.0152 0.0207
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Echinococcus granulosus expressed protein 0.0034 0.01 0.0134
Brugia malayi Thioredoxin reductase 0.0085 0.042 0.0592
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0088 0.0443 0.0603
Onchocerca volvulus Cathepsin L homolog 0.0081 0.0399 0.1214
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0007 0.0078
Echinococcus multilocularis histone deacetylase 0.0042 0.0151 0.0149
Entamoeba histolytica cysteine protease, putative 0.0032 0.0086 0.0491
Echinococcus multilocularis serine:threonine protein kinase N2 0.0088 0.0443 0.0441
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0042 0.0152 0.0208
Brugia malayi G protein-coupled receptor F59B2.13 0.0057 0.0244 0.0343
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0042 0.0152 0.0878
Loa Loa (eye worm) CAMK/PKD protein kinase 0.023 0.1333 0.188
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0034 0.01 0.0141
Trichomonas vaginalis penicillin-binding protein, putative 0.0143 0.0785 0.4513
Echinococcus granulosus netrin receptor unc 5 0.0031 0.0081 0.0108
Loa Loa (eye worm) hypothetical protein 0.0147 0.0812 0.1146
Schistosoma mansoni fatty acid binding protein 0.0111 0.0586 0.08
Echinococcus multilocularis neuropeptide Y receptor 0.0057 0.0244 0.0241
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0364 0.2177 0.2978
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0036 0.0442
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0042 0.0152 0.0207
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0032 0.0086 0.1079
Entamoeba histolytica cysteine protease, putative 0.0032 0.0086 0.0491
Brugia malayi Cathepsin L-like precursor 0.0081 0.0399 0.0563
Brugia malayi hypothetical protein 0.0057 0.0244 0.0343
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0032 0.0086 0.0409
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0033 0.0095 0.0093
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0063 0.006
Echinococcus granulosus cathepsin L cysteine protease 0.0032 0.0086 0.0115
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0143 0.0785 0.1108
Brugia malayi hypothetical protein 0.0057 0.0244 0.0343
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0057 0.0244 0.0241
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0033 0.0095 0.0354
Brugia malayi cathepsin Z-like cysteine proteinase 0.0032 0.0086 0.0121
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0029 0.0072 0.0697
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0032 0.0086 0.0116
Onchocerca volvulus Deterin homolog 0.0483 0.2928 0.9055
Schistosoma mansoni DNA polymerase eta 0.0058 0.0255 0.0347
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0029 0.0077
Echinococcus granulosus apoptotic protease activating factor 1 0.0124 0.0665 0.0907
Brugia malayi C1-like domain containing protein 0.023 0.1333 0.188
Giardia lamblia Cathepsin B precursor 0.0158 0.0881 0.5114
Brugia malayi prolyl oligopeptidase family protein 0.0532 0.3233 0.4559
Entamoeba histolytica cysteine protease, putative 0.0081 0.0399 0.2313
Brugia malayi Immunoglobulin I-set domain containing protein 0.0031 0.0081 0.0114
Leishmania major cathepsin L-like protease 0.0081 0.0399 0.3935
Giardia lamblia Cathepsin L precursor 0.0032 0.0086 0.0492
Brugia malayi Tachykinin-like peptides receptor 99D 0.0057 0.0244 0.0343
Brugia malayi neuropeptide F receptor 0.0057 0.0244 0.0343
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Schistosoma mansoni cathepsin C 0.0032 0.0086 0.0116
Echinococcus multilocularis expressed protein 0.0034 0.01 0.0098
Entamoeba histolytica hypothetical protein 0.008 0.0393 0.2274
Brugia malayi Lipocalin / cytosolic fatty-acid binding protein family protein 0.1145 0.7091 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0074 0.0352 0.8366
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0029 0.0072 0.0096
Mycobacterium ulcerans DNA polymerase IV 0.0058 0.0255 0.3233
Echinococcus multilocularis snurportin 1 0.0297 0.1758 0.1757
Trichomonas vaginalis AGC family protein kinase 0.0093 0.0474 0.2686
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Echinococcus granulosus uncharacterized sodium dependent transporter 0.003 0.0074 0.0098
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0255 0.2508
Onchocerca volvulus 0.0094 0.0477 0.1455
Giardia lamblia Cathepsin B precursor 0.0158 0.0881 0.5114
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0364 0.2177 0.3069
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0032 0.0086 0.0492
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0114 0.057
Brugia malayi cathepsin L-like precursor 0.0081 0.0399 0.0563
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0032 0.0086 0.0121
Entamoeba histolytica PH domain containing protein kinase, putative 0.0174 0.0983 0.5707
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0011
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0102 0.0527 0.0719
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0057 0.0244 0.0332
Onchocerca volvulus 0.0057 0.0244 0.0732
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0062 0.0278 0.0276
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0297 0.1758 0.248
Echinococcus multilocularis rhodopsin orphan GPCR 0.0057 0.0244 0.0241
Echinococcus granulosus serotonin receptor 0.0057 0.0244 0.033
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0057 0.0244 0.0332
Trypanosoma cruzi DNA polymerase kappa, putative 0.0058 0.0255 0.0955
Loa Loa (eye worm) hypothetical protein 0.0081 0.0399 0.0563
Loa Loa (eye worm) cathepsin B 0.0158 0.0881 0.1242
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0042 0.0152 0.0878
Toxoplasma gondii aldehyde dehydrogenase 0.0123 0.0661 0.6528
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0063 0.0605
Plasmodium falciparum serine repeat antigen 5 0.0032 0.0086 0.2021
Entamoeba histolytica protein kinase, putative 0.0088 0.0443 0.2568
Entamoeba histolytica cysteine proteinase, putative 0.0032 0.0086 0.0491
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Onchocerca volvulus 0.0232 0.1349 0.4158
Schistosoma mansoni amine GPCR 0.0057 0.0244 0.0332
Plasmodium falciparum peptidase, putative 0.0042 0.0152 0.361
Toxoplasma gondii prolyl endopeptidase 0.0042 0.0152 0.1495
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0032 0.0086 0.1079
Trypanosoma cruzi cysteine peptidase, putative 0.0081 0.0399 0.1499
Brugia malayi Cathepsin L-like precursor 0.0081 0.0399 0.0563
Loa Loa (eye worm) hypothetical protein 0.0081 0.0399 0.0563
Plasmodium falciparum thioredoxin reductase 0.0029 0.0072 0.1684
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.008 0.039 0.055
Schistosoma mansoni neuropeptide receptor 0.0057 0.0244 0.0332
Echinococcus multilocularis serine:threonine protein kinase 38 0.0088 0.0443 0.0441
Schistosoma mansoni sodium/chloride dependent transporter 0.0175 0.0985 0.1347
Schistosoma mansoni P2X receptor subunit 0.0134 0.0727 0.0994
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0088 0.0443 0.0625
Giardia lamblia Encystation-specific protease 0.0032 0.0086 0.0492
Brugia malayi Cathepsin L-like precursor 0.0081 0.0399 0.0563
Trypanosoma brucei histone deacetylase, putative 0.0042 0.0151 0.1483
Schistosoma mansoni hypothetical protein 0.0031 0.0081 0.0109
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0007 0.0011
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0532 0.3233 1
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0032 0.0086 0.1079
Schistosoma mansoni hypothetical protein 0.0033 0.0095 0.0129
Plasmodium falciparum serine repeat antigen 8 0.0032 0.0086 0.2021
Loa Loa (eye worm) hypothetical protein 0.0042 0.0152 0.0215
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0141 0.138
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.035 0.1312
Echinococcus multilocularis cathepsin b 0.044 0.2655 0.2654
Plasmodium vivax vivapain-3 0.0032 0.0086 0.1079
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0038 0.0129 0.1265
Brugia malayi polk-prov protein 0.0018 0.0001 0.0002
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0114 0.057
Onchocerca volvulus 0.0057 0.0244 0.0732
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0175 0.0985 0.1389
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0032 0.0086 0.0409
Entamoeba histolytica hypothetical protein 0.0036 0.0112 0.0642
Echinococcus granulosus myotubularin protein 13 0.0085 0.0424 0.0577
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0032 0.0086 0.1079
Plasmodium vivax proteasome subunit beta type-5, putative 0.008 0.039 0.4956
Entamoeba histolytica protein kinase, putative 0.0093 0.0474 0.2749
Entamoeba histolytica cysteine proteinase 2 0.0032 0.0086 0.0491
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0007 0.0007
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0057 0.0244 0.0332
Entamoeba histolytica cysteine protease, putative 0.0032 0.0086 0.0491
Loa Loa (eye worm) hypothetical protein 0.003 0.0074 0.0104
Plasmodium vivax unspecified product 0.0032 0.0086 0.1079
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0036 0.0051
Leishmania major DNA polymerase eta, putative 0.0058 0.0255 0.2508
Echinococcus multilocularis geminin 0.1179 0.7306 0.7305
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0057 0.0244 0.0332
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0088 0.0443 0.0441
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0057 0.0244 0.0332
Echinococcus granulosus cysteine protease 0.0032 0.0086 0.0115
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0038 0.0129 0.1265
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0058 0.0255 0.0392
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0036 0.0201
Toxoplasma gondii histone lysine methyltransferase SET1 0.011 0.0578 0.5706
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.008 0.0393 0.0554
Echinococcus multilocularis caspase 2 0.0124 0.0665 0.0663
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0399 0.2246
Loa Loa (eye worm) hypothetical protein 0.0058 0.0255 0.036
Brugia malayi Protein kinase domain containing protein 0.0103 0.0537 0.0757
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0041 0.0147 0.0768
Echinococcus granulosus biogenic amine 5HT receptor 0.0057 0.0244 0.033
Trypanosoma cruzi DNA polymerase kappa, putative 0.0058 0.0255 0.0955
Echinococcus granulosus cathepsin L 0.0032 0.0086 0.0115
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0022 0.0023 0.0032
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0029 0.0072 0.0095
Loa Loa (eye worm) hypothetical protein 0.003 0.0074 0.0104
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0016 0.0023
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0057 0.0244 0.0241
Loa Loa (eye worm) proteasome subunit beta type 1 0.0062 0.0278 0.0392
Brugia malayi proteasome subunit beta type 2 0.0038 0.0129 0.0182
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0032 0.0086 0.0121
Echinococcus multilocularis rhodopsin orphan GPCR 0.0057 0.0244 0.0241
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0081 0.0399 0.2246
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0057 0.0244 0.0343
Mycobacterium tuberculosis Probable oxidoreductase 0.0215 0.1238 0.215
Loa Loa (eye worm) variant SH3 domain-containing protein 0.008 0.0393 0.0554
Trichomonas vaginalis penicillin-binding protein, putative 0.0143 0.0785 0.4513
Brugia malayi Histone deacetylase family protein 0.0042 0.0151 0.0213
Plasmodium vivax proteasome subunit beta type-2, putative 0.0038 0.0129 0.1631
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0029 0.0072 0.0899
Trypanosoma brucei proteasome subunit beta type-5, putative 0.008 0.039 0.3845
Entamoeba histolytica cysteine protease, putative 0.0032 0.0086 0.0491
Schistosoma mansoni hypothetical protein 0.0152 0.0847 0.1157
Brugia malayi MH2 domain containing protein 0.0475 0.2878 0.4059
Toxoplasma gondii hypothetical protein 0.003 0.0074 0.0715
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0057 0.0244 0.033
Schistosoma mansoni atypical protein kinase C 0.0275 0.1621 0.2217
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0057 0.0244 0.0332
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0062 0.0278 0.1535
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0032 0.0086 0.0409
Echinococcus multilocularis rhodopsin orphan GPCR 0.0057 0.0244 0.0241
Brugia malayi Protein kinase domain containing protein 0.0033 0.0096 0.0136
Trichomonas vaginalis esterase, putative 0.0143 0.0785 0.4513
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0255 0.2508
Echinococcus multilocularis sodium and chloride dependent glycine 0.003 0.0074 0.0071
Loa Loa (eye worm) hypothetical protein 0.0031 0.0082 0.0115
Giardia lamblia Cathepsin L precursor 0.0032 0.0086 0.0492
Echinococcus multilocularis p2X purinoceptor 4 0.0134 0.0727 0.0725
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0086 0.0409
Toxoplasma gondii LsmAD domain-containing protein 0.0074 0.0352 0.3464
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0086 0.0428 0.2413
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0112 0.015
Mycobacterium ulcerans DNA polymerase IV 0.0058 0.0255 0.3233
Toxoplasma gondii hypothetical protein 0.0042 0.0152 0.1495
Entamoeba histolytica prolyl oligopeptidase family protein 0.0042 0.0152 0.0878
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0114 0.016
Plasmodium vivax vivapain-2 0.0081 0.0399 0.5073
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.008 0.039 0.1464
Echinococcus multilocularis neuropeptide receptor A26 0.0057 0.0244 0.0241
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0288 0.0393
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0288 0.0393
Echinococcus multilocularis acylamino acid releasing enzyme 0.0042 0.0152 0.015
Leishmania major proteasome beta 5 subunit, putative 0.008 0.039 0.3845
Schistosoma mansoni hypothetical protein 0.1179 0.7306 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0119 0.0636 0.0868
Mycobacterium tuberculosis Probable lipase LipD 0.0143 0.0785 0.1341
Loa Loa (eye worm) hypothetical protein 0.008 0.0393 0.0554
Echinococcus granulosus serine:threonine protein kinase N2 0.0169 0.0951 0.13
Trypanosoma cruzi cruzipain precursor, putative 0.0081 0.0399 0.1499
Entamoeba histolytica cysteine protease, putative 0.0032 0.0086 0.0491
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0058 0.0255 0.036
Echinococcus granulosus dna polymerase kappa 0.0058 0.0255 0.0346
Loa Loa (eye worm) hypothetical protein 0.0081 0.0399 0.0563
Plasmodium falciparum serine repeat antigen 6 0.0032 0.0086 0.2021
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0057 0.0244 0.0241
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0179 0.1012 1
Schistosoma mansoni protein kinase C 0.0088 0.044 0.0601
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Schistosoma mansoni hypothetical protein 0.0036 0.0112 0.0151
Loa Loa (eye worm) hypothetical protein 0.003 0.0074 0.0104
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.035 0.3444
Echinococcus multilocularis serotonin receptor 0.06 0.3663 0.3662
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0057 0.0244 0.0343
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0036 0.0442
Schistosoma mansoni histone deacetylase hda2 0.0042 0.0151 0.0205
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Onchocerca volvulus 0.003 0.0074 0.0205
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0058 0.0255 0.14
Echinococcus granulosus Desert hedgehog protein 0.0209 0.1204 0.1646
Onchocerca volvulus 0.0057 0.0244 0.0732
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0112 0.0151
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0081 0.0399 0.0563
Schistosoma mansoni serine/threonine protein kinase 0.0088 0.0443 0.0604
Onchocerca volvulus 0.003 0.0074 0.0205
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0032 0.0086 0.2021
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.003 0.0074 0.0099
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0532 0.3233 0.4424
Onchocerca volvulus 0.0057 0.0244 0.0732
Schistosoma mansoni aldehyde dehydrogenase 0.0123 0.0661 0.0903
Echinococcus multilocularis lysosomal alpha glucosidase 0.0162 0.0907 0.0905
Schistosoma mansoni biogenic amine (5HT) receptor 0.0057 0.0244 0.0332
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0032 0.0086 0.1079
Echinococcus multilocularis serine:threonine protein kinase N2 0.0255 0.1492 0.149
Onchocerca volvulus Cell death protein 3 homolog 0.0124 0.0665 0.2039
Trypanosoma brucei histone deacetylase 3 0.0042 0.0151 0.1483
Brugia malayi Papain family cysteine protease containing protein 0.0032 0.0086 0.0121
Plasmodium vivax hypothetical protein, conserved 0.0143 0.0785 1
Brugia malayi Cathepsin L-like cysteine proteinase 0.0081 0.0399 0.0563
Loa Loa (eye worm) hypothetical protein 0.0034 0.01 0.0141
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0198 0.028
Echinococcus granulosus protein kinase C gamma type 0.0239 0.139 0.1899
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Echinococcus multilocularis cathepsin L cysteine protease 0.0081 0.0399 0.0397
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0007 0.0146
Schistosoma mansoni Smad4 0.0032 0.0091 0.0123
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0036 0.0051
Toxoplasma gondii NADPH-glutathione reductase 0.0029 0.0072 0.0697
Brugia malayi Dopamine receptor protein 2 0.0057 0.0244 0.0343
Brugia malayi ORL1-like opioid receptor 0.0057 0.0244 0.0343
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0032 0.0086 0.1079
Loa Loa (eye worm) acetyltransferase 0.014 0.0771 0.1087
Onchocerca volvulus 0.0056 0.0237 0.0711
Echinococcus granulosus unc 13 munc13 0.0088 0.044 0.06
Brugia malayi RNA, U transporter 1 0.0079 0.0386 0.0544
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0114 0.0152
Trypanosoma cruzi 20S proteasome subunit 0.0038 0.0129 0.0482
Schistosoma mansoni histamine h1 receptor 0.0057 0.0244 0.0332
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0007 0.0007
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0114 0.016
Schistosoma mansoni caspase-7 (C14 family) 0.0124 0.0665 0.0908
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0193 0.1102 0.1907
Echinococcus granulosus neuropeptide FF receptor 2 0.0057 0.0244 0.033
Loa Loa (eye worm) hypothetical protein 0.0143 0.0785 0.1108
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0912 0.5626 1
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0062 0.0278 0.2735
Schistosoma mansoni fatty acid binding protein 0.0111 0.0586 0.08
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.023 0.1333 0.188
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0255 0.2508
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0179 0.1012 0.3808
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0364 0.2177 0.2175
Plasmodium vivax glutathione reductase, putative 0.0085 0.042 0.5337
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0032 0.0091 0.0123
Entamoeba histolytica cysteine protease, putative 0.0032 0.0086 0.0491
Brugia malayi proteasome subunit beta type 1 0.0062 0.0278 0.0392
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0032 0.0086 0.0116
Trypanosoma brucei cysteine peptidase C (CPC) 0.0158 0.0881 0.8699
Brugia malayi Serotonin receptor 0.0057 0.0244 0.0343
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0153 0.0849 0.1198
Schistosoma mansoni tyrosine kinase 0.0172 0.0968 0.1323
Brugia malayi Protein kinase domain containing protein 0.0088 0.0443 0.0625
Schistosoma mansoni myosin xvIII 0.0057 0.0244 0.0332
Echinococcus multilocularis rhodopsin orphan GPCR 0.0057 0.0244 0.0241
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0073 0.035 0.2024
Schistosoma mansoni amine GPCR 0.0057 0.0244 0.0332
Echinococcus granulosus proteasome prosome macropain 0.008 0.039 0.0531
Onchocerca volvulus 0.0057 0.0244 0.0732
Mycobacterium ulcerans hypothetical protein 0.0024 0.0036 0.0442
Schistosoma mansoni unc-13 (munc13) 0.009 0.0452 0.0617
Schistosoma mansoni tyrosine kinase 0.0103 0.0537 0.0733
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0032 0.0086 0.0116
Echinococcus multilocularis raf serine:threonine protein kinase 0.0082 0.0404 0.0402
Onchocerca volvulus 0.0143 0.0785 0.2412
Brugia malayi Melatonin receptor type 1A 0.0057 0.0244 0.0343
Trypanosoma brucei oligopeptidase b 0.0042 0.0152 0.1495
Schistosoma mansoni cathepsin B (C01 family) 0.0032 0.0086 0.0116
Echinococcus multilocularis allatostatin A receptor 0.0057 0.0244 0.0241
Brugia malayi putative neuropeptide receptor 0.0057 0.0244 0.0343
Brugia malayi glutathione reductase 0.0085 0.042 0.0592
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0399 0.2246
Loa Loa (eye worm) hypothetical protein 0.044 0.2655 0.3745
Mycobacterium ulcerans hypothetical protein 0.0143 0.0785 1
Plasmodium falciparum glutathione reductase 0.0085 0.042 1
Brugia malayi hypothetical protein 0.0137 0.0747 0.1053
Echinococcus granulosus rhodopsin orphan GPCR 0.0057 0.0244 0.033
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0078 0.0076
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0036 0.0442
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0062 0.0278 0.1042
Echinococcus granulosus histone deacetylase 6 0.0042 0.0151 0.0204
Loa Loa (eye worm) prolyl oligopeptidase 0.0042 0.0152 0.0215
Loa Loa (eye worm) lipocalin/cytosolic fatty-acid binding protein family protein 0.1145 0.7091 1
Echinococcus multilocularis thioredoxin glutathione reductase 0.0085 0.0423 0.0421
Trypanosoma brucei proteasome beta 6 subunit 0.0062 0.0278 0.2735
Trichomonas vaginalis AGC family protein kinase 0.0093 0.0474 0.2686
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0255 0.2508
Echinococcus granulosus Dipeptidyl peptidase 9 0.0179 0.1012 0.1383
Schistosoma mansoni hypothetical protein 0.0057 0.0244 0.0332
Echinococcus multilocularis smad 0.0032 0.0091 0.0089
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.0457 0.0624
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0057 0.0244 0.033
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0032 0.0091 0.0089
Giardia lamblia Cathepsin B precursor 0.0032 0.0086 0.0492
Mycobacterium tuberculosis Probable esterase LipL 0.0143 0.0785 0.1341
Trypanosoma cruzi cysteine proteinase, putative 0.0032 0.0086 0.0319
Trichomonas vaginalis AGC family protein kinase 0.0088 0.0443 0.2503
Schistosoma mansoni aldehyde dehydrogenase 0.0123 0.0661 0.0903
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0042 0.0152 0.1495
Plasmodium falciparum cysteine proteinase falcipain 3 0.0081 0.0399 0.9505
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.035 0.1312
Echinococcus multilocularis unc 13 (munc13) 0.0088 0.044 0.0438
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0078 0.0104
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0073 0.035 0.3444
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0066 0.0301 0.0474
Toxoplasma gondii cathepsin CPC1 0.0032 0.0086 0.0837
Echinococcus multilocularis cysteine protease 0.0081 0.0399 0.0397
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0112 0.011
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0029 0.0072 0.1684
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0103 0.0537 0.0732
Entamoeba histolytica cysteine protease, putative 0.0032 0.0086 0.0491
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0255 0.2508
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0399 0.2246
Brugia malayi Smad1 0.0032 0.0091 0.0128
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0038 0.0129 0.0127
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0036 0.0442
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.003 0.0074 0.0099
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0029 0.0072 0.007
Giardia lamblia Alanyl dipeptidyl peptidase 0.0042 0.0152 0.0879
Schistosoma mansoni ran 0.0021 0.0016 0.002
Trypanosoma brucei prolyl endopeptidase 0.0042 0.0152 0.1495
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0029 0.0072 0.0697
Loa Loa (eye worm) solute carrier family 6 member 4 0.0175 0.0985 0.1389
Giardia lamblia Cathepsin L precursor 0.0032 0.0086 0.0492
Plasmodium vivax unspecified product 0.0032 0.0086 0.1079
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0149 0.0828 0.1167
Echinococcus granulosus somatostatin receptor 0.0057 0.0244 0.033
Entamoeba histolytica cysteine protease, putative 0.0032 0.0086 0.0491
Onchocerca volvulus 0.0035 0.0106 0.0304
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0288 0.0393
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0032 0.0086 0.0116
Echinococcus granulosus dna polymerase eta 0.0058 0.0255 0.0346
Echinococcus multilocularis 0.01 0.0516 0.0514
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0057 0.0244 0.0343
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0039 0.0134 0.0181
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0057 0.0244 0.0332
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0057 0.0244 0.0343
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0114 0.1109
Loa Loa (eye worm) hypothetical protein 0.008 0.0393 0.0554
Toxoplasma gondii hypothetical protein 0.003 0.0074 0.0715
Brugia malayi MH2 domain containing protein 0.0032 0.0091 0.0128
Brugia malayi Dopamine receptor protein 1 0.0057 0.0244 0.0343
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0038 0.0129 0.3056
Echinococcus multilocularis cathepsin L 0.0032 0.0086 0.0084
Trichomonas vaginalis AGC family protein kinase 0.0093 0.0474 0.2686
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0016 0.0014
Schistosoma mansoni P2X receptor subunit 0.0134 0.0727 0.0994
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0073 0.035 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0036 0.0051
Onchocerca volvulus 0.0124 0.0665 0.2039
Brugia malayi Sodium:neurotransmitter symporter family protein 0.003 0.0074 0.0104
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.008 0.039 0.2192
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0062 0.0278 0.0377
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0029 0.0072 0.0697
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0078 0.0758
Trichomonas vaginalis AGC family protein kinase 0.0088 0.0443 0.2503
Echinococcus granulosus rhodopsin orphan GPCR 0.0057 0.0244 0.033
Plasmodium falciparum serine repeat antigen 1 0.0032 0.0086 0.2021
Schistosoma mansoni loxhd1 0.0019 0.0007 0.0008
Brugia malayi fibroinase precursor 0.0032 0.0086 0.0121
Echinococcus granulosus sodium and chloride dependent glycine 0.003 0.0074 0.0098
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0483 0.2928 0.4129
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.044 0.2655 0.3633
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.1721 1
Brugia malayi hypothetical protein 0.0074 0.0352 0.0496
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0114 0.0652
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.01 0.0493
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0125 0.0721
Schistosoma mansoni histone deacetylase 4 5 0.0042 0.0151 0.0205
Schistosoma mansoni terminal deoxycytidyl transferase 0.0058 0.0255 0.0347
Echinococcus granulosus rhodopsin orphan GPCR 0.0057 0.0244 0.033
Brugia malayi Cathepsin L-like precursor 0.0081 0.0399 0.0563
Entamoeba histolytica hypothetical protein 0.0036 0.0112 0.0642
Entamoeba histolytica cysteine protease, putative 0.0032 0.0086 0.0491
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0016 0.0056
Schistosoma mansoni hypothetical protein 0.0124 0.0665 0.0908
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.003 0.0074 0.0099
Onchocerca volvulus Cathepsin L homolog 0.0081 0.0399 0.1214
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0032 0.0086 0.2021
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0088 0.0443 0.0625
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0057 0.0244 0.0332
Brugia malayi hypothetical protein 0.0057 0.0244 0.0343
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0032 0.0086 0.0409
Echinococcus multilocularis serine threonine protein kinase 0.0239 0.139 0.1388
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0114 0.0606 0.0604
Echinococcus multilocularis G-protein coupled receptor, putative 0.0057 0.0244 0.0241
Echinococcus granulosus cathepsin L cysteine proteinase 0.0081 0.0399 0.0543
Schistosoma mansoni biogenic amine receptor 0.0057 0.0244 0.0332
Schistosoma mansoni diacylglycerol kinase theta 0.008 0.0393 0.0535
Echinococcus multilocularis neuropeptide Y receptor 0.0057 0.0244 0.0241
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0158 0.0881 0.1204
Schistosoma mansoni smad 0.0032 0.0091 0.0123
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0033 0.0095 0.0128
Echinococcus multilocularis tissue type plasminogen activator 0.0035 0.0106 0.0103
Schistosoma mansoni tyrosine kinase 0.0172 0.0968 0.1323
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0036 0.0201
Trichomonas vaginalis AGC family protein kinase 0.0093 0.0474 0.2686
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0072 0.0265
Brugia malayi hypothetical protein 0.0057 0.0244 0.0343
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0029 0.0072 0.0697
Loa Loa (eye worm) hypothetical protein 0.0143 0.0785 0.1108
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0072 0.0265
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0081 0.0399 0.2246
Trypanosoma brucei rac serine-threonine kinase, putative 0.0093 0.0474 0.4677
Mycobacterium tuberculosis Probable peptidase 0.0042 0.0152 0.0208
Loa Loa (eye worm) prolyl oligopeptidase 0.0532 0.3233 0.4559
Trichomonas vaginalis AGC family protein kinase 0.0093 0.0474 0.2686
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0032 0.0086 0.0491
Echinococcus multilocularis sodium and chloride dependent glycine 0.003 0.0074 0.0071
Echinococcus granulosus RNA directed DNA polymerase 0.0143 0.0786 0.1073
Echinococcus multilocularis neuropeptide FF receptor 2 0.0057 0.0244 0.0241
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0007 0.0007
Schistosoma mansoni microtubule-associated protein tau 0.0678 0.4155 0.5687
Schistosoma mansoni hypothetical protein 0.0035 0.0106 0.0143
Brugia malayi hypothetical protein 0.0124 0.0665 0.0938
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0062 0.0278 0.1607
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Schistosoma mansoni neuropeptide f receptor 76f 0.0057 0.0244 0.0332
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0007 0.0005
Brugia malayi Inositol-1 0.0073 0.035 0.0493
Loa Loa (eye worm) RasGEF domain-containing protein 0.008 0.0393 0.0554
Loa Loa (eye worm) hypothetical protein 0.0088 0.044 0.0621
Trichomonas vaginalis bromodomain-containing protein, putative 0.0041 0.0147 0.0768
Brugia malayi G-protein coupled receptor 0.0057 0.0244 0.0343
Loa Loa (eye worm) MH1 domain-containing protein 0.0032 0.0091 0.0128
Trypanosoma cruzi PAB1-binding protein , putative 0.0074 0.0352 0.1319
Echinococcus granulosus protein kinase c epsilon type 0.0343 0.2045 0.2796
Loa Loa (eye worm) glutathione reductase 0.0085 0.042 0.0592
Schistosoma mansoni opsin-like receptor 0.0057 0.0244 0.0332
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0179 0.1012 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0074 0.0104
Brugia malayi Pleckstrin Homology Domain 0.0085 0.0424 0.0597
Echinococcus granulosus N chimaerin 0.008 0.0393 0.0534
Trypanosoma cruzi trypanothione reductase, putative 0.0029 0.0072 0.0265
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0057 0.0244 0.0332
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0125 0.0722
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.003 0.0074 0.0715
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0066 0.0301 0.2206
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0032 0.0086 0.0409
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0062 0.0278 0.2735
Plasmodium vivax serine-repeat antigen (SERA) 0.0032 0.0086 0.1079
Loa Loa (eye worm) hypothetical protein 0.0483 0.2928 0.4129
Echinococcus granulosus rhodopsin orphan GPCR 0.0057 0.0244 0.033
Leishmania major hypothetical protein, conserved 0.0035 0.0106 0.1031
Trypanosoma cruzi cysteine peptidase, putative 0.0081 0.0399 0.1499
Toxoplasma gondii kringle domain-containing protein 0.0035 0.0106 0.1031
Trypanosoma brucei DNA polymerase IV, putative 0.0058 0.0255 0.2508
Brugia malayi Protein kinase domain containing protein 0.0088 0.0443 0.0625
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0029 0.0077
Schistosoma mansoni serine/threonine protein kinase 0.0088 0.0443 0.0604
Mycobacterium leprae proteasome (beta subunit) PrcB 0.008 0.039 0.2945
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0057 0.0244 0.0241
Echinococcus granulosus NDR protein kinase 0.0088 0.0443 0.0603
Leishmania major cathepsin L-like protease 0.0081 0.0399 0.3935
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.014 0.0771 0.0769
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.044 0.2655 0.3633
Loa Loa (eye worm) hypothetical protein 0.0124 0.0665 0.0938
Echinococcus granulosus neuropeptide s receptor 0.0057 0.0244 0.033
Loa Loa (eye worm) histone deacetylase 0.0042 0.0151 0.0213
Schistosoma mansoni lipoxygenase 0.0114 0.0606 0.0828
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.0399 0.3935
Echinococcus granulosus histone deacetylase 7 0.0042 0.0151 0.0204
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0399 0.2246
Trypanosoma cruzi cysteine proteinase, putative 0.0032 0.0086 0.0319
Brugia malayi Protein kinase c protein 2 0.0233 0.1354 0.191
Trypanosoma cruzi histone deacetylase, putative 0.0042 0.0151 0.0565
Trypanosoma brucei DNA polymerase eta, putative 0.0058 0.0255 0.2508
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0057 0.0244 0.0343
Brugia malayi larval opioid receptor 0.0057 0.0244 0.0343
Echinococcus multilocularis Diacylglycerol kinase theta 0.008 0.0393 0.039
Brugia malayi Protein kinase domain containing protein 0.0037 0.0117 0.0165
Echinococcus granulosus neuropeptide Y receptor 0.0057 0.0244 0.033
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.0399 0.3935
Echinococcus granulosus tachykinin peptides receptor 99D 0.0057 0.0244 0.033
Leishmania major hypothetical protein, conserved 0.0143 0.0785 0.7758
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0057 0.0244 0.0332
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0114 0.057
Brugia malayi acetyltransferase, GNAT family protein 0.014 0.0771 0.1087
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0033 0.0095 0.0545
Mycobacterium tuberculosis Conserved hypothetical protein 0.0058 0.0255 0.0392
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0057 0.0244 0.0332
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0032 0.0086 0.0837
Brugia malayi follicle stimulating hormone receptor 0.0285 0.1683 0.2373
Mycobacterium ulcerans lipase LipD 0.0143 0.0785 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0032 0.0086 0.0121
Loa Loa (eye worm) melatonin receptor type 1A 0.0057 0.0244 0.0343
Brugia malayi prolyl oligopeptidase family protein 0.0042 0.0152 0.0215
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0033 0.0095 0.0928
Trichomonas vaginalis D-aminoacylase, putative 0.0143 0.0785 0.4513
Schistosoma mansoni amine GPCR 0.0057 0.0244 0.0332
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0088 0.044 0.0438
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0081 0.0399 0.2246
Giardia lamblia Alanyl dipeptidyl peptidase 0.0042 0.0152 0.0879
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0038 0.0129 0.0663
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0158 0.0881 0.3313
Loa Loa (eye worm) G-protein coupled receptor 0.0057 0.0244 0.0343
Schistosoma mansoni inhibitor of apoptosis protein 0.0483 0.2928 0.4007
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0152 0.0569
Echinococcus granulosus insulin receptor 0.0103 0.0537 0.0732
Entamoeba histolytica prolyl oligopeptidase family protein 0.0042 0.0152 0.0878
Plasmodium falciparum histone deacetylase 2 0.0042 0.0151 0.3581
Schistosoma mansoni protein kinase C mu 0.008 0.0393 0.0535
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0038 0.0129 0.0174
Entamoeba histolytica deoxycytidyl transferase, putative 0.0058 0.0255 0.1474
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.003 0.0074 0.0104
Entamoeba histolytica hypothetical protein 0.0032 0.0086 0.0491
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0142 0.0783 0.6215
Onchocerca volvulus 0.003 0.0074 0.0205
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.0288 0.0407
Loa Loa (eye worm) hypothetical protein 0.0422 0.254 0.3582
Trypanosoma brucei hypothetical protein, conserved 0.0143 0.0785 0.7758
Brugia malayi prolyl oligopeptidase family protein 0.0042 0.0152 0.0215
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0038 0.0129 0.0663
Giardia lamblia Fructose-bisphosphate aldolase 0.0291 0.1721 1
Mycobacterium leprae Probable lipase LipE 0.0143 0.0785 0.6237
Loa Loa (eye worm) hypothetical protein 0.0124 0.0665 0.0938
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0038 0.0129 0.0175
Plasmodium falciparum cysteine repeat modular protein 1 0.0035 0.0106 0.2489
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0041 0.0147 0.1859
Echinococcus granulosus prolyl endopeptidase 0.0042 0.0152 0.0206
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0042 0.0152 0.1495
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0057 0.0244 0.0332
Giardia lamblia NADH oxidase lateral transfer candidate 0.0029 0.0072 0.041
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0086 0.0409
Schistosoma mansoni serine/threonine protein kinase 0.0088 0.0443 0.0604
Echinococcus granulosus acylamino acid releasing enzyme 0.0042 0.0152 0.0206
Loa Loa (eye worm) ctsf protein 0.0081 0.0399 0.0563
Leishmania major histone deacetylase, putative 0.0042 0.0151 0.1483
Toxoplasma gondii peptidylprolyl isomerase 0.0033 0.0095 0.0928
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0029 0.0072 0.0697
Brugia malayi cathepsin L precursor 0.0032 0.0086 0.0121
Mycobacterium tuberculosis Conserved protein 0.0143 0.0785 0.1341
Echinococcus granulosus raf serine:threonine protein kinase 0.0082 0.0404 0.055
Plasmodium vivax serine-repeat antigen (SERA) 0.0032 0.0086 0.1079
Schistosoma mansoni neuropeptide F-like receptor 0.0057 0.0244 0.0332
Plasmodium falciparum serine repeat antigen 3 0.0032 0.0086 0.2021
Toxoplasma gondii cathepsin B 0.0158 0.0881 0.8699
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0123 0.0661 0.0902
Echinococcus multilocularis histone deacetylase 6 0.0042 0.0151 0.0149
Echinococcus granulosus histone acetyltransferase KAT2B 0.0041 0.0147 0.0198
Leishmania major histone deacetylase, putative 0.0042 0.0151 0.1483
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0032 0.0086 0.1079
Echinococcus multilocularis rhodopsin orphan GPCR 0.0057 0.0244 0.0241
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0057 0.0244 0.033
Echinococcus multilocularis fmrfamide receptor 0.0057 0.0244 0.0241
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0088
Brugia malayi MH1 domain containing protein 0.0032 0.0091 0.0128
Schistosoma mansoni hypothetical protein 0.0297 0.1758 0.2405
Loa Loa (eye worm) hypothetical protein 0.0032 0.0086 0.0121
Schistosoma mansoni inositol monophosphatase 0.0073 0.035 0.0477
Loa Loa (eye worm) TK/EGFR protein kinase 0.0323 0.1919 0.2707
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0078 0.0105
Brugia malayi Protein kinase domain containing protein 0.0083 0.0408 0.0575
Loa Loa (eye worm) neuropeptide F receptor 0.0057 0.0244 0.0343
Echinococcus granulosus neuropeptide Y receptor 0.0057 0.0244 0.033
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0057 0.0244 0.0241
Trypanosoma brucei unspecified product 0.0058 0.0255 0.2508
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0029 0.0072 0.1684
Echinococcus granulosus uncharacterized sodium dependent transporter 0.003 0.0074 0.0098
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0158 0.0881 0.8699
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0038 0.0129 0.0482
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0179 0.1012 1
Brugia malayi Sodium:neurotransmitter symporter family protein 0.003 0.0074 0.0104
Leishmania major cathepsin L-like protease 0.0081 0.0399 0.3935
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0032 0.0086 0.0837
Entamoeba histolytica hypothetical protein 0.0036 0.0112 0.0642
Echinococcus granulosus thioredoxin glutathione reductase 0.0085 0.0423 0.0576
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0081 0.0399 0.0563
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.003 0.0074 0.0715
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0038 0.0129 0.0175
Onchocerca volvulus 0.0024 0.0036 0.0088
Onchocerca volvulus 0.0081 0.0399 0.1214
Giardia lamblia Cathepsin L-like protease 0.0032 0.0086 0.0492
Schistosoma mansoni rab6-interacting 0.0019 0.0007 0.0008
Giardia lamblia Cathepsin L precursor 0.0032 0.0086 0.0492
Onchocerca volvulus 0.0057 0.0244 0.0732
Echinococcus multilocularis histone deacetylase 7 0.0042 0.0151 0.0149
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.0288 0.0407
Leishmania major cathepsin L-like protease 0.0081 0.0399 0.3935
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0057 0.0244 0.0241
Loa Loa (eye worm) MH2 domain-containing protein 0.0032 0.0091 0.0128
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0102 0.0527 0.0525
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0064 0.0084
Brugia malayi beta-lactamase 0.0143 0.0785 0.1108
Brugia malayi Papain family cysteine protease containing protein 0.0032 0.0086 0.0121
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0319 0.1895 0.1893
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0364 0.2177 0.2978
Echinococcus multilocularis Smad4 0.0032 0.0091 0.0089
Loa Loa (eye worm) proteasome subunit beta type 2 0.0038 0.0129 0.0182
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0255 0.2508
Echinococcus granulosus nuclear factor of activated T cells 5 0.0301 0.1782 0.2436
Loa Loa (eye worm) hypothetical protein 0.0035 0.0106 0.0149
Toxoplasma gondii diacylglycerol kinase, putative 0.008 0.0393 0.387
Schistosoma mansoni hypothetical protein 0.0057 0.0244 0.0332
Giardia lamblia Cathepsin L precursor 0.0032 0.0086 0.0492
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0057 0.0244 0.0343
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0193 0.1102 0.1907
Plasmodium falciparum proteasome subunit beta type-5 0.008 0.039 0.9285
Schistosoma mansoni sodium/chloride dependent transporter 0.003 0.0074 0.0099
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0016 0.0356
Schistosoma mansoni smad1 5 8 and 0.0032 0.0091 0.0123
Echinococcus multilocularis tar DNA binding protein 0.0064 0.0288 0.0286
Schistosoma mansoni opsin-like receptor 0.0057 0.0244 0.0332
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0078 0.0105
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0032 0.0086 0.1079
Loa Loa (eye worm) hypothetical protein 0.0333 0.1985 0.2799
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0032 0.0086 0.2021
Trichomonas vaginalis AGC family protein kinase 0.0093 0.0474 0.2686
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0255 0.2508
Echinococcus granulosus fatty acid binding protein FABP2 0.0111 0.0586 0.0799
Entamoeba histolytica cysteine proteinase, putative 0.0032 0.0086 0.0491
Echinococcus multilocularis beta LACTamase domain containing family member 0.0143 0.0785 0.0783
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.008 0.039 0.1464
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0364 0.2177 0.2175
Echinococcus granulosus death domain containing protein 0.0031 0.0081 0.0108
Echinococcus multilocularis Ankyrin 0.0031 0.0082 0.008
Echinococcus multilocularis G protein coupled receptor 139 0.0057 0.0244 0.0241
Schistosoma mansoni netrin receptor unc5 0.0031 0.0081 0.0109
Toxoplasma gondii ABC1 family protein 0.0143 0.0785 0.7758
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0032 0.0086 0.0409
Onchocerca volvulus 0.0057 0.0244 0.0732
Loa Loa (eye worm) neuropeptide F receptor 0.0057 0.0244 0.0343
Schistosoma mansoni smad1 5 8 and 0.0032 0.0091 0.0123
Loa Loa (eye worm) norepinephrine transporter 0.0175 0.0985 0.1389
Entamoeba histolytica cysteine proteinase, putative 0.0032 0.0086 0.0491
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0114 0.0422
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0301 0.1782 0.178
Loa Loa (eye worm) Smad1 0.0032 0.0091 0.0128
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0364 0.2177 0.2977
Schistosoma mansoni tyrosine kinase 0.0172 0.0968 0.1323
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.1721 1
Echinococcus granulosus cathepsin b 0.044 0.2655 0.3633
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0032 0.0086 0.0116
Mycobacterium leprae conserved hypothetical protein 0.0143 0.0785 0.6237
Echinococcus multilocularis netrin receptor unc 5 0.0031 0.0081 0.0079
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0483 0.2928 0.2927
Plasmodium vivax histone deacetylase 2, putative 0.0042 0.0151 0.1911
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.0661 0.8415
Brugia malayi Cathepsin L-like precursor 0.0081 0.0399 0.0563
Echinococcus granulosus cathepsin L 0.0032 0.0086 0.0115
Echinococcus granulosus dnaJ subfamily B 0.0791 0.4867 0.6661
Brugia malayi RhoGAP domain containing protein 0.008 0.0393 0.0554
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.0399 0.3935
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.003 0.0074 0.0071
Trypanosoma brucei prolyl oligopeptidase, putative 0.0042 0.0152 0.1495
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0057 0.0244 0.0332
Schistosoma mansoni cpg binding protein 0.0059 0.0257 0.035
Echinococcus granulosus lysosomal alpha glucosidase 0.0162 0.0907 0.1238
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0288 0.0393
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0042 0.0152 0.0969
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0114 0.057
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0143 0.0785 0.1108
Onchocerca volvulus Cathepsin L homolog 0.0032 0.0086 0.0243
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0142 0.0783 0.1336
Loa Loa (eye worm) hypothetical protein 0.0024 0.0036 0.0051
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0532 0.3233 0.4423
Brugia malayi RhoGAP domain containing protein 0.008 0.0393 0.0554
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0078 0.0105
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.008 0.0393 0.039
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0364 0.2177 0.2978
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0032 0.0086 0.0409
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.008 0.0393 0.0534
Mycobacterium tuberculosis Probable reductase 0.0193 0.1102 0.1907
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0123 0.0661 0.1118
Loa Loa (eye worm) histone deacetylase 7A 0.0042 0.0151 0.0213
Entamoeba histolytica cysteine proteinase, putative 0.0032 0.0086 0.0491
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0114 0.1109
Echinococcus granulosus Protein kinase C brain isozyme 0.0319 0.1895 0.2591
Entamoeba histolytica cysteine protease, putative 0.0032 0.0086 0.0491
Echinococcus granulosus rhodopsin orphan GPCR 0.0057 0.0244 0.033
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0174 0.0979 0.1337
Entamoeba histolytica hypothetical protein, conserved 0.0042 0.0152 0.0878
Plasmodium vivax amine transporter, putative 0.003 0.0074 0.0922
Mycobacterium ulcerans proteasome PrcB 0.008 0.039 0.4956
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0255 0.2508
Trypanosoma cruzi DNA polymerase kappa, putative 0.0058 0.0255 0.0955
Schistosoma mansoni tyrosine kinase 0.0103 0.0537 0.0733
Schistosoma mansoni cathepsin S (C01 family) 0.0032 0.0086 0.0116
Plasmodium vivax SET domain protein, putative 0.003 0.0078 0.0977
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0198 0.028
Brugia malayi beta-lactamase family protein 0.0143 0.0785 0.1108
Trypanosoma cruzi cysteine peptidase, putative 0.0081 0.0399 0.1499
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0158 0.0881 0.5071
Echinococcus granulosus histone deacetylase 6 0.0042 0.0151 0.0204
Onchocerca volvulus 0.0057 0.0244 0.0732
Schistosoma mansoni ran 0.0021 0.0016 0.002
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0272 0.1596 0.2183
Plasmodium falciparum histone deacetylase, putative 0.0042 0.0151 0.3581
Echinococcus multilocularis histone deacetylase 6 0.0042 0.0151 0.0149
Echinococcus granulosus cathepsin l cysteine peptidase 0.0081 0.0399 0.0543
Echinococcus granulosus cathepsin l1 0.0081 0.0399 0.0543
Trypanosoma brucei PAB1-binding protein , putative 0.0074 0.0352 0.3464
Echinococcus multilocularis Rac GTPase activating protein 1 0.008 0.0393 0.039
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0088 0.0443 0.0603
Echinococcus multilocularis g-protein coupled receptor 0.0057 0.0244 0.0241
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0029 0.0072 0.0697
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.0399 0.3935
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0042 0.0152 0.0799
Loa Loa (eye worm) hypothetical protein 0.0032 0.0086 0.0121
Loa Loa (eye worm) hypothetical protein 0.0024 0.0036 0.0051
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0143 0.0786 0.0784
Loa Loa (eye worm) hypothetical protein 0.0042 0.0151 0.0213
Loa Loa (eye worm) histone methyltransferase 0.0018 0.0002 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0081 0.0399 0.2246
Brugia malayi AKH receptor 0.0057 0.0244 0.0343
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0483 0.2928 0.4129
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0029 0.0072 0.0697
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0016 0.0147
Brugia malayi cathepsin L-like cysteine proteinase 0.0032 0.0086 0.0121
Loa Loa (eye worm) G-protein coupled receptor 0.0057 0.0244 0.0343
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0057 0.0244 0.033
Loa Loa (eye worm) hypothetical protein 0.0175 0.0985 0.1389
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0036 0.0201
Entamoeba histolytica cysteine proteinase 1, putative 0.0032 0.0086 0.0491
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Onchocerca volvulus 0.0057 0.0244 0.0732
Brugia malayi Doublecortin family protein 0.0019 0.0007 0.0011
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0152 0.1927
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0142 0.0783 0.9967
Brugia malayi Pre-SET motif family protein 0.003 0.0078 0.011
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0062 0.0278 0.0378
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0399 0.2246
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0198 0.028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0399 0.2246
Brugia malayi cathepsin Z-like cysteine proteinase 0.0032 0.0086 0.0121
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0062 0.0278 0.6606
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0029 0.0072 0.0899
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0063 0.0605
Schistosoma mansoni biogenic amine receptor 0.0057 0.0244 0.0332
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0072 0.0265
Loa Loa (eye worm) hypothetical protein 0.0057 0.0245 0.0346
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0255 0.2508
Echinococcus multilocularis cathepsin b 0.044 0.2655 0.2654
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0029 0.0072 0.0064
Plasmodium vivax hypothetical protein, conserved 0.003 0.0074 0.0922
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0057 0.0244 0.033
Entamoeba histolytica cysteine protease, putative 0.0032 0.0086 0.0491
Entamoeba histolytica cysteine proteinase, putative 0.0081 0.0399 0.2313
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.0399 0.3935
Echinococcus multilocularis cpg binding protein 0.0059 0.0257 0.0255
Loa Loa (eye worm) hypothetical protein 0.003 0.0078 0.011
Loa Loa (eye worm) TK/ROR protein kinase 0.0037 0.0117 0.0165
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0291 0.1721 1
Echinococcus granulosus allatostatin A receptor 0.0057 0.0244 0.033
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0483 0.2928 0.4006
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Loa Loa (eye worm) hypothetical protein 0.0333 0.1985 0.2799
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0057 0.0244 0.0332
Trypanosoma brucei histone deacetylase 4 0.0042 0.0151 0.1483
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0032 0.0086 0.0409
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0532 0.3233 0.3231
Schistosoma mansoni cathepsin F (C01 family) 0.0081 0.0399 0.0545
Echinococcus granulosus neuropeptide receptor 0.0057 0.0244 0.033
Echinococcus granulosus biogenic amine 5HT receptor 0.06 0.3663 0.5013
Loa Loa (eye worm) hypothetical protein 0.0223 0.1291 0.1821
Echinococcus granulosus beta LACTamase domain containing family member 0.0143 0.0785 0.1072
Trichomonas vaginalis rotamase, putative 0.0033 0.0095 0.0463
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.003 0.0074 0.0071
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0033 0.0095 0.0354
Entamoeba histolytica protein kinase, putative 0.0093 0.0474 0.2749
Giardia lamblia Hypothetical protein 0.0032 0.0086 0.0492
Entamoeba histolytica prolyl oligopeptidase family protein 0.0042 0.0152 0.0878
Schistosoma mansoni alpha-glucosidase 0.0139 0.0765 0.1045
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0193 0.1102 0.8872
Brugia malayi Protein kinase domain containing protein 0.0093 0.0474 0.0669
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0057 0.0244 0.0343
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0036 0.0442
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0029 0.0072 0.0899
Onchocerca volvulus 0.0081 0.0399 0.1214
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0031 0.0081 0.0079
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0032 0.0086 0.0121
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0032 0.0086 0.0409
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0081 0.0399 0.2246
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0016 0.0056
Echinococcus granulosus tm gpcr rhodopsin 0.0057 0.0244 0.033
Loa Loa (eye worm) hypothetical protein 0.0175 0.0985 0.1389
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.008 0.039 0.0532
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.003 0.0074 0.0104
Brugia malayi Cell death protein 3 precursor 0.0124 0.0665 0.0938
Onchocerca volvulus 0.0483 0.2928 0.9055
Echinococcus multilocularis protein kinase c eta type 0.008 0.0393 0.039
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0081 0.0399 0.2246
Echinococcus granulosus g protein coupled receptor 0.0057 0.0244 0.033
Brugia malayi Papain family cysteine protease containing protein 0.0081 0.0399 0.0563
Schistosoma mansoni alpha-glucosidase 0.0139 0.0765 0.1045
Trypanosoma cruzi oligopeptidase b 0.0042 0.0152 0.0569
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0078 0.0105
Brugia malayi Kringle domain containing protein 0.0035 0.0106 0.0149
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0042 0.0152 0.0569
Echinococcus granulosus TGF beta signal transducer SmadC 0.0032 0.0091 0.0122
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0057 0.0244 0.0332
Schistosoma mansoni protein kinase C mu 0.023 0.1333 0.1823
Echinococcus granulosus peptide allatostatin:somatostatin 0.0057 0.0244 0.033
Echinococcus multilocularis prolyl endopeptidase 0.0042 0.0152 0.015
Giardia lamblia Cathepsin L-like protease 0.0032 0.0086 0.0492
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0035 0.0106 0.1329
Echinococcus multilocularis microtubule associated protein 2 0.0678 0.4155 0.4154
Schistosoma mansoni neuropeptide receptor 0.0057 0.0244 0.0332
Schistosoma mansoni serine/threonine protein kinase 0.0319 0.1895 0.2592
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0042 0.0152 0.1495
Schistosoma mansoni rab6-interacting 0.0019 0.0007 0.0008
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0036 0.0442
Loa Loa (eye worm) hypothetical protein 0.0085 0.0424 0.0597
Trypanosoma brucei glucosidase, putative 0.0036 0.0114 0.1109
Leishmania major proteasome beta 2 subunit, putative 0.0038 0.0129 0.1265
Echinococcus multilocularis lysosomal alpha glucosidase 0.0162 0.0907 0.0905
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0029 0.0072 0.0265
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0031 0.0081 0.0114
Brugia malayi hypothetical protein 0.0019 0.0007 0.0011
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0081 0.0399 0.9505
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0083 0.0408 0.0555
Echinococcus multilocularis fatty acid binding protein FABP2 0.0111 0.0586 0.0584
Echinococcus multilocularis dna polymerase eta 0.0058 0.0255 0.0253
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0029 0.0072 0.0265
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0114 0.057
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.0399 0.3935
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0085 0.042 0.0687
Brugia malayi hypothetical protein 0.0057 0.0244 0.0343
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Echinococcus granulosus snurportin 1 0.0297 0.1758 0.2405
Loa Loa (eye worm) hypothetical protein 0.0031 0.0081 0.0114
Schistosoma mansoni hypothetical protein 0.0057 0.0244 0.0332
Loa Loa (eye worm) hypothetical protein 0.008 0.0393 0.0554
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.0399 0.3935
Brugia malayi beta-lactamase family protein 0.0143 0.0785 0.1108
Echinococcus multilocularis neuropeptide receptor 0.0057 0.0244 0.0241
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0057 0.0244 0.0732
Echinococcus granulosus dro:myosuppressin receptor 0.0057 0.0244 0.033
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.003 0.0074 0.0099
Schistosoma mansoni vav2 0.0085 0.0424 0.0578
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0073 0.035 0.1955
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0057 0.0244 0.0332
Trichomonas vaginalis DNA polymerase eta, putative 0.0058 0.0255 0.14
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0106 0.0393
Toxoplasma gondii cathepsin CPC2 0.0032 0.0086 0.0837
Giardia lamblia Cysteine protease 0.0032 0.0086 0.0492
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0029 0.0106
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0152 0.0569
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.014 0.0771 0.1053
Toxoplasma gondii proteasome subunit beta type, putative 0.008 0.039 0.3845
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.0399 0.3935
Leishmania major GTP-binding protein, putative 0.0021 0.0016 0.0147
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0285 0.1683 0.2373
Brugia malayi Variant SH3 domain containing protein 0.008 0.0393 0.0554
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0042 0.0152 0.1495
Toxoplasma gondii AGC kinase 0.0088 0.0443 0.4369
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0029 0.0072 0.0697
Mycobacterium tuberculosis Conserved protein 0.0143 0.0785 0.1341
Leishmania major cathepsin L-like protease 0.0081 0.0399 0.3935
Leishmania major cathepsin L-like protease 0.0081 0.0399 0.3935
Loa Loa (eye worm) hypothetical protein 0.0333 0.1985 0.2799
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0143 0.0785 0.1341
Plasmodium vivax thioredoxin reductase, putative 0.0085 0.042 0.5337
Echinococcus multilocularis protein kinase c iota type 0.0268 0.1575 0.1573
Trichomonas vaginalis AGC family protein kinase 0.0093 0.0474 0.2686
Mycobacterium tuberculosis Probable dehydrogenase 0.0193 0.1102 0.1907
Brugia malayi cathepsin B-like cysteine proteinase 0.044 0.2655 0.3745
Onchocerca volvulus 0.0081 0.0399 0.1214
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Trichomonas vaginalis glutathione reductase, putative 0.0029 0.0072 0.0326
Loa Loa (eye worm) hypothetical protein 0.0042 0.0152 0.0215
Schistosoma mansoni diacylglycerol kinase theta 0.008 0.0393 0.0535
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.003 0.0074 0.0099
Trypanosoma brucei unspecified product 0.004 0.0141 0.138
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0143 0.0785 0.1341
Entamoeba histolytica hypothetical protein 0.0023 0.0029 0.0163
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0032 0.0086 0.0492
Onchocerca volvulus 0.0057 0.0244 0.0732
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0057 0.0244 0.0241
Schistosoma mansoni serine/threonine protein kinase 0.0082 0.0404 0.0551
Toxoplasma gondii preprocathepsin c precursor, putative 0.0032 0.0086 0.0837
Echinococcus granulosus rhodopsin orphan GPCR 0.0057 0.0244 0.033
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.008 0.039 0.0633
Schistosoma mansoni opsin-like receptor 0.0057 0.0244 0.0332
Loa Loa (eye worm) AGC/NDR protein kinase 0.0088 0.0443 0.0625
Loa Loa (eye worm) RhoGAP domain-containing protein 0.008 0.0393 0.0554
Echinococcus multilocularis p2X purinoceptor 4 0.0134 0.0727 0.0725
Trypanosoma cruzi prolyl endopeptidase 0.0042 0.0152 0.0569
Echinococcus granulosus caspase 2 0.0124 0.0665 0.0907
Entamoeba histolytica protein kinase, putative 0.0088 0.0443 0.2568
Loa Loa (eye worm) hypothetical protein 0.0032 0.0086 0.0121
Echinococcus granulosus fatty acid binding protein FABP2 0.0111 0.0586 0.0799
Echinococcus multilocularis protein kinase c epsilon type 0.0343 0.2045 0.2043
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Schistosoma mansoni P2X receptor subunit 0.0134 0.0727 0.0994
Brugia malayi Dopamine receptor 0.0057 0.0244 0.0343
Giardia lamblia Cathepsin B precursor 0.0032 0.0086 0.0492
Onchocerca volvulus Prolyl endopeptidase homolog 0.0042 0.0152 0.0449
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0114 0.0652
Brugia malayi protein kinase C II. 0.0343 0.2045 0.2883
Onchocerca volvulus 0.0333 0.1985 0.613
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.044 0.2655 0.3633
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.1721 1
Brugia malayi G-protein coupled receptor 0.0057 0.0244 0.0343
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.1721 1
Echinococcus multilocularis serotonin transporter 0.0175 0.0985 0.0983
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.003 0.0074 0.0071
Trypanosoma cruzi histone deacetylase, putative 0.0042 0.0151 0.0565
Loa Loa (eye worm) hypothetical protein 0.0143 0.0785 0.1108
Toxoplasma gondii histone deacetylase HDAC1 0.0042 0.0151 0.1483
Echinococcus granulosus p2X purinoceptor 4 0.0134 0.0727 0.0993
Brugia malayi Hint module family protein 0.0057 0.0245 0.0346
Trichomonas vaginalis D-aminoacylase, putative 0.0143 0.0785 0.4513
Leishmania major cysteine peptidase A (CPA) 0.0081 0.0399 0.3935
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0193 0.1102 0.1907
Brugia malayi sulfakinin receptor protein 0.0057 0.0244 0.0343
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0215 0.1238 0.215
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0399 0.2246
Schistosoma mansoni biogenic amine (5HT) receptor 0.06 0.3663 0.5013
Loa Loa (eye worm) hypothetical protein 0.0483 0.2928 0.4129
Echinococcus granulosus protein kinase c iota type 0.0268 0.1575 0.2153
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0042 0.0152 0.0207
Onchocerca volvulus 0.0057 0.0244 0.0732
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0029 0.0072 0.0697
Trypanosoma cruzi cysteine protease, putative 0.0032 0.0086 0.0319
Trichomonas vaginalis D-aminoacylase, putative 0.0143 0.0785 0.4513
Echinococcus multilocularis neuropeptides capa receptor 0.0057 0.0244 0.0241
Schistosoma mansoni hypothetical protein 0.1179 0.7306 1
Schistosoma mansoni serine/threonine kinase 0.0088 0.0443 0.0604
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0073 0.035 0.1955
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0058 0.0255 0.2508
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0032 0.0086 0.0409
Echinococcus multilocularis g protein coupled receptor 0.0057 0.0244 0.0241
Brugia malayi hypothetical protein 0.0057 0.0244 0.0343
Echinococcus multilocularis fmrfamide receptor 0.0057 0.0244 0.0241
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0036 0.0343
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0081 0.0399 0.9505
Onchocerca volvulus 0.0143 0.0785 0.2412
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0051 0.0072
Giardia lamblia Cysteine protease 0.0032 0.0086 0.0492
Leishmania major importin beta-1 subunit, putative 0.0023 0.0029 0.0277
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0032 0.0086 0.0409
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0057 0.0244 0.0332
Brugia malayi protein kinase C3,putative 0.0182 0.1034 0.1459
Echinococcus granulosus histone acetyltransferase KAT2B 0.0136 0.0746 0.1019
Brugia malayi prolyl oligopeptidase family protein 0.0179 0.1012 0.1427
Plasmodium falciparum serine repeat antigen 7 0.0032 0.0086 0.2021
Schistosoma mansoni ankyrin 23/unc44 0.0031 0.0081 0.0109
Brugia malayi Papain family cysteine protease containing protein 0.0032 0.0086 0.0121
Trypanosoma cruzi DNA polymerase eta, putative 0.0058 0.0255 0.0955
Brugia malayi TAR-binding protein 0.0064 0.0288 0.0407
Brugia malayi RE15519p 0.0057 0.0244 0.0343
Onchocerca volvulus 0.0081 0.0399 0.1214
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0483 0.2928 0.4007
Entamoeba histolytica cysteine protease, putative 0.0032 0.0086 0.0491
Schistosoma mansoni rotamase 0.0034 0.01 0.0135
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.003 0.0074 0.0099
Echinococcus granulosus g protein coupled receptor 0.0057 0.0244 0.033
Schistosoma mansoni cpg binding protein 0.0056 0.0237 0.0322
Onchocerca volvulus Neuropeptide F receptor homolog 0.0057 0.0244 0.0732
Brugia malayi Cytochrome P450 family protein 0.0026 0.0051 0.0072
Loa Loa (eye worm) beta-lactamase 0.0143 0.0785 0.1108
Echinococcus granulosus epidermal growth factor receptor 0.0174 0.0979 0.1337
Onchocerca volvulus 0.0057 0.0244 0.0732
Schistosoma mansoni hypothetical protein 0.0019 0.0007 0.0008
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.003 0.0074 0.0098
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0114 0.057
Giardia lamblia Proteasome subunit beta type 5 precursor 0.008 0.039 0.226
Onchocerca volvulus 0.0057 0.0244 0.0732
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0399 0.2246
Loa Loa (eye worm) hypothetical protein 0.0137 0.0747 0.1053
Echinococcus multilocularis rhodopsin orphan GPCR 0.0057 0.0244 0.0241
Giardia lamblia Cysteine protease 0.0032 0.0086 0.0492
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0125 0.2965
Plasmodium falciparum thioredoxin reductase 0.0085 0.042 1
Brugia malayi Ras association domain family 1 isoform A 0.008 0.0393 0.0554
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0114 0.0606 0.0827
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0042 0.0152 0.0799
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0143 0.0785 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0162 0.0907 0.1279
Trypanosoma cruzi trypanothione reductase, putative 0.0085 0.042 0.1577
Loa Loa (eye worm) hypothetical protein 0.008 0.0393 0.0554
Echinococcus granulosus serotonin transporter 0.0175 0.0985 0.1346
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0032 0.0086 0.0116
Entamoeba histolytica cysteine protease, putative 0.0032 0.0086 0.0491
Onchocerca volvulus 0.0032 0.0086 0.0243
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0042 0.0152 0.1495
Loa Loa (eye worm) cysteine protease 0.0081 0.0399 0.0563
Onchocerca volvulus 0.0232 0.1349 0.4159
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.003 0.0074 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.0661 0.8415
Giardia lamblia Cysteine protease 0.0032 0.0086 0.0492
Plasmodium falciparum serine repeat antigen 2 0.0032 0.0086 0.2021
Mycobacterium ulcerans beta-lactamase 0.0143 0.0785 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Entamoeba histolytica cysteine protease, putative 0.0032 0.0086 0.0491
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0081 0.0399 0.2246
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0057 0.0244 0.0241
Echinococcus multilocularis inhibitor of apoptosis protein 0.0483 0.2928 0.2927
Schistosoma mansoni biogenic amine receptor 0.0057 0.0244 0.0332
Echinococcus multilocularis cathepsin L 0.0032 0.0086 0.0084
Brugia malayi diacylglycerol kinase 0.008 0.0393 0.0554
Echinococcus multilocularis neuropeptide receptor 0.0057 0.0244 0.0241
Brugia malayi Hr1 repeat family protein 0.0088 0.0443 0.0625
Giardia lamblia Cathepsin B precursor 0.0032 0.0086 0.0492
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0058 0.0255 0.0347
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0088 0.0443 0.0603
Echinococcus multilocularis RNA directed DNA polymerase 0.0143 0.0786 0.0784
Loa Loa (eye worm) hypothetical protein 0.0143 0.0786 0.1109
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0032 0.0086 0.1079
Leishmania major DNA polymerase kappa, putative 0.0058 0.0255 0.2508
Schistosoma mansoni hypothetical protein 0.0791 0.4867 0.6661
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.0399 0.3935
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0288 0.0393
Loa Loa (eye worm) serotonin transporter b 0.0175 0.0985 0.1389
Trypanosoma cruzi oligopeptidase b 0.0042 0.0152 0.0569
Trypanosoma cruzi major cysteine proteinase, putative 0.0032 0.0086 0.0319
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0029 0.0072 0.0899
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0114 0.057
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0036 0.0343
Brugia malayi putative neuropeptide receptor NPR1 0.0057 0.0244 0.0343
Echinococcus granulosus RUN 0.0019 0.0007 0.0007
Onchocerca volvulus 0.0081 0.0399 0.1214
Schistosoma mansoni serine/threonine protein kinase 0.0343 0.2045 0.2797
Brugia malayi MH1 domain containing protein 0.0032 0.0091 0.0128
Loa Loa (eye worm) TAR-binding protein 0.0064 0.0288 0.0407
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0088 0.0443 0.0625
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.0661 0.8415
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.003 0.0074 0.0715
Echinococcus multilocularis epidermal growth factor receptor 0.0323 0.1919 0.1917
Trypanosoma brucei DNA polymerase IV, putative 0.0058 0.0255 0.2508
Schistosoma mansoni hypothetical protein 0.0483 0.2928 0.4007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.0399 0.3935
Loa Loa (eye worm) hypothetical protein 0.008 0.0393 0.0554
Giardia lamblia Proteasome subunit beta type 1 0.0062 0.0278 0.1608
Echinococcus multilocularis N chimaerin 0.008 0.0393 0.039
Toxoplasma gondii cathepsin CPL 0.0081 0.0399 0.3935
Brugia malayi p70 ribosomal S6 kinase beta 0.0088 0.0443 0.0625
Schistosoma mansoni inositol monophosphatase 0.0073 0.035 0.0477
Loa Loa (eye worm) hypothetical protein 0.0074 0.0352 0.0496
Entamoeba histolytica Ran family GTPase 0.0021 0.0016 0.0086
Echinococcus multilocularis insulin receptor 0.0103 0.0537 0.0535
Echinococcus multilocularis cysteine protease 0.0081 0.0399 0.0397
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0399 0.2246
Echinococcus multilocularis rhodopsin orphan GPCR 0.0057 0.0244 0.0241
Brugia malayi hypothetical protein 0.0057 0.0244 0.0343
Echinococcus granulosus g-protein coupled receptor 0.0057 0.0244 0.033
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0078 0.0076
Trypanosoma cruzi cysteine peptidase, putative 0.0081 0.0399 0.1499
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0057 0.0244 0.0241
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0081 0.0399 0.2246
Schistosoma mansoni cathepsin F (C01 family) 0.0081 0.0399 0.0545
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0088 0.044 0.06
Schistosoma mansoni adenoreceptor 0.0057 0.0244 0.0332
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0029 0.0072 0.0899
Brugia malayi Papain family cysteine protease containing protein 0.0032 0.0086 0.0121
Echinococcus multilocularis proteasome (prosome, macropain) 0.008 0.039 0.0388
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0088 0.0443 0.0441
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.1721 1
Loa Loa (eye worm) raf kinase 0.008 0.0393 0.0554
Echinococcus multilocularis RUN 0.0019 0.0007 0.0005
Loa Loa (eye worm) hypothetical protein 0.003 0.0074 0.0104
Brugia malayi RNA binding protein 0.0064 0.0288 0.0407
Echinococcus granulosus histone deacetylase 6 0.0042 0.0151 0.0204
Onchocerca volvulus Netrin receptor homolog 0.0031 0.0081 0.0228
Mycobacterium tuberculosis Probable lipase LipE 0.0143 0.0785 0.1341
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.0255 0.2508
Echinococcus granulosus inositol monophosphatase 1 0.0073 0.035 0.0476
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0032 0.0086 0.0409
Echinococcus multilocularis serotonin receptor 0.06 0.3663 0.3662
Loa Loa (eye worm) hypothetical protein 0.008 0.0393 0.0554
Brugia malayi Glycosyl hydrolases family 31 protein 0.0162 0.0907 0.1279
Mycobacterium ulcerans esterase/lipase LipP 0.0143 0.0785 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Trichomonas vaginalis AGC family protein kinase 0.0088 0.0443 0.2503
Brugia malayi Hint module family protein 0.0057 0.0245 0.0346
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0057 0.0244 0.0241
Echinococcus granulosus neuropeptides capa receptor 0.0057 0.0244 0.033
Brugia malayi hypothetical protein 0.003 0.0074 0.0104
Onchocerca volvulus 0.0057 0.0244 0.0732
Echinococcus granulosus Rac GTPase activating protein 1 0.008 0.0393 0.0534
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0081 0.0399 0.2246
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0114 0.0422
Loa Loa (eye worm) hypothetical protein 0.0143 0.0785 0.1108
Plasmodium vivax proteasome subunit beta type-1, putative 0.0062 0.0278 0.3526
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0179 0.1012 0.3808
Loa Loa (eye worm) hypothetical protein 0.0147 0.0812 0.1146
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0038 0.0129 0.0743
Plasmodium falciparum glutathione reductase 0.0029 0.0072 0.1684
Echinococcus granulosus alpha 1A adrenergic receptor 0.0057 0.0244 0.033
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0022 0.0023 0.0032
Echinococcus multilocularis neuropeptides capa receptor 0.0057 0.0244 0.0241
Echinococcus granulosus cathepsin l1 0.0081 0.0399 0.0543
Echinococcus granulosus cpg binding protein 0.0059 0.0257 0.0349
Loa Loa (eye worm) hypothetical protein 0.0042 0.0152 0.0215
Giardia lamblia DINP protein human, muc B family 0.0058 0.0255 0.1475
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0032 0.0086 0.0116
Loa Loa (eye worm) hypothetical protein 0.0042 0.0151 0.0213
Echinococcus granulosus sodium and chloride dependent glycine 0.003 0.0074 0.0098
Echinococcus granulosus smad 0.0032 0.0091 0.0122
Echinococcus multilocularis fatty acid binding protein FABP2 0.0111 0.0586 0.0584
Plasmodium vivax vivapain-1 0.0032 0.0086 0.1079
Schistosoma mansoni serine/threonine protein kinase 0.0083 0.0408 0.0557
Loa Loa (eye worm) subtilase 0.0272 0.1596 0.2251
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0152 0.0799
Echinococcus granulosus G protein coupled receptor 139 0.0057 0.0244 0.033
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Brugia malayi F/Y-rich N-terminus family protein 0.0018 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0057 0.0245 0.0346
Echinococcus granulosus geminin 0.1179 0.7306 1
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0081 0.0399 0.1499
Schistosoma mansoni amine GPCR 0.0057 0.0244 0.0332
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Echinococcus granulosus hypothetical protein 0.0057 0.0244 0.033
Echinococcus granulosus sex peptide receptor 0.0057 0.0244 0.033
Treponema pallidum sodium- and chloride- dependent transporter 0.0175 0.0985 0.554
Onchocerca volvulus 0.0227 0.1318 0.4062
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0058 0.0255 0.0346
Loa Loa (eye worm) hypothetical protein 0.003 0.0074 0.0104
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.1721 1
Loa Loa (eye worm) AGC/AKT protein kinase 0.0093 0.0474 0.0669
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0081 0.0399 0.0397
Echinococcus granulosus protein kinase c eta type 0.008 0.0393 0.0534
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.044 0.2655 0.3633
Giardia lamblia Cathepsin B precursor 0.0158 0.0881 0.5114
Echinococcus granulosus 7tm_1 domain containing protein 0.0057 0.0244 0.033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0399 0.2246
Echinococcus granulosus g protein coupled receptor 0.0057 0.0244 0.033
Schistosoma mansoni growth hormone secretagogue receptor 0.0057 0.0244 0.0332
Echinococcus multilocularis inositol monophosphatase 1 0.0073 0.035 0.0347
Trichomonas vaginalis inositol monophosphatase, putative 0.0073 0.035 0.1955
Loa Loa (eye worm) hypothetical protein 0.0018 0.0001 0.0002
Plasmodium vivax histone deacetylase, putative 0.0042 0.0151 0.1911
Schistosoma mansoni tyrosine kinase 0.0174 0.0979 0.1338
Loa Loa (eye worm) hypothetical protein 0.0081 0.0399 0.0563
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0058 0.0255 0.0253
Echinococcus multilocularis cathepsin L cysteine protease 0.0081 0.0399 0.0397
Brugia malayi Uncoordinated protein 44 0.0031 0.0081 0.0114
Loa Loa (eye worm) fibroinase 0.0081 0.0399 0.0563
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0081 0.0399 0.3935
Leishmania major trypanothione reductase 0.0085 0.042 0.414
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0042 0.0152 0.0569
Brugia malayi Cathepsin L-like precursor 0.0081 0.0399 0.0563
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0143 0.0785 0.1341
Echinococcus granulosus p2X purinoceptor 4 0.0134 0.0727 0.0993
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0175 0.0985 0.1347
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0032 0.0086 0.0409
Onchocerca volvulus 0.0175 0.0985 0.3032
Onchocerca volvulus 0.003 0.0078 0.0219
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Echinococcus granulosus Diacylglycerol kinase theta 0.008 0.0393 0.0534
Schistosoma mansoni histone deacetylase 4 5 0.0042 0.0151 0.0205
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0029 0.0072 0.0265
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0057 0.0244 0.0332
Brugia malayi hypothetical protein 0.0036 0.0112 0.0158
Plasmodium falciparum amino acid transporter, putative 0.003 0.0074 0.1727
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.019 0.108 0.1524
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0193 0.1102 0.1907
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0399 0.2246
Brugia malayi Serotonin receptor 0.0057 0.0244 0.0343
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0032 0.0086 0.0409
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0032 0.0086 0.0116
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0399 0.2246
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Entamoeba histolytica cysteine protease, putative 0.0032 0.0086 0.0491
Echinococcus granulosus orexin receptor type 2 0.0057 0.0244 0.033
Echinococcus granulosus serine:threonine protein kinase N2 0.0088 0.0443 0.0603
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0057 0.0244 0.0343
Trypanosoma cruzi major cysteine proteinase, putative 0.0032 0.0086 0.0319
Schistosoma mansoni cathepsin F (C01 family) 0.0081 0.0399 0.0545
Treponema pallidum fructose-bisphosphate aldolase 0.0291 0.1721 1
Onchocerca volvulus 0.0143 0.0785 0.2412
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0215 0.1238 0.215
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.044 0.2655 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0074 0.0352 0.8366
Trichomonas vaginalis set domain proteins, putative 0.0232 0.1348 0.7812
Leishmania major cathepsin L-like protease 0.0081 0.0399 0.3935
Loa Loa (eye worm) hypothetical protein 0.0032 0.0086 0.0121
Loa Loa (eye worm) hypothetical protein 0.0049 0.0198 0.028
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0088 0.0443 0.0441
Schistosoma mansoni unc-13 (munc13) 0.0088 0.044 0.0601
Loa Loa (eye worm) TYRA-2 protein 0.0057 0.0244 0.0343
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0032 0.0086 0.0409
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Giardia lamblia Cathepsin L precursor 0.0032 0.0086 0.0492
Schistosoma mansoni sodium/chloride dependent transporter 0.0032 0.0089 0.012
Brugia malayi GnHR receptor homolog 0.0057 0.0244 0.0343
Onchocerca volvulus 0.0057 0.0244 0.0732
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0007 0.0005
Brugia malayi RhoGEF domain containing protein 0.008 0.0393 0.0554
Onchocerca volvulus Cathepsin F homolog 0.0081 0.0399 0.1214
Plasmodium vivax vivapain-2 0.0081 0.0399 0.5073
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0041 0.0147 0.1442
Echinococcus multilocularis neuropeptide s receptor 0.0057 0.0244 0.0241
Loa Loa (eye worm) hypothetical protein 0.0175 0.0985 0.1389
Brugia malayi cathepsin F-like cysteine proteinase 0.0032 0.0086 0.0121
Echinococcus granulosus tm gpcr rhodopsin 0.0057 0.0244 0.033
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0057 0.0244 0.0241
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0032 0.0086 0.0409
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0029 0.0072 0.0101
Schistosoma mansoni lipoxygenase 0.008 0.039 0.0532
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0016 0.019
Schistosoma mansoni importin beta-1 0.0028 0.0063 0.0084
Echinococcus granulosus tar DNA binding protein 0.0064 0.0288 0.0392
Entamoeba histolytica cysteine protease, putative 0.0032 0.0086 0.0491
Onchocerca volvulus 0.0057 0.0244 0.0732
Trypanosoma cruzi DNA polymerase kappa, putative 0.0058 0.0255 0.0955
Brugia malayi Sodium:neurotransmitter symporter family protein 0.003 0.0074 0.0104
Loa Loa (eye worm) hypothetical protein 0.0057 0.0244 0.0343
Echinococcus multilocularis dro:myosuppressin receptor 0.0057 0.0244 0.0241
Trypanosoma cruzi histone deacetylase, putative 0.0042 0.0151 0.0565
Echinococcus granulosus tm gpcr rhodopsin 0.0057 0.0244 0.033
Schistosoma mansoni amine GPCR 0.0057 0.0244 0.0332
Echinococcus granulosus Smad4 0.0032 0.0091 0.0122
Brugia malayi hypothetical protein 0.0019 0.0007 0.0011
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0007 0.0005
Trypanosoma brucei DNA polymerase IV, putative 0.0058 0.0255 0.2508
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0399 0.2246
Onchocerca volvulus 0.0088 0.044 0.1342
Echinococcus granulosus tissue type plasminogen activator 0.0035 0.0106 0.0142
Brugia malayi prolyl oligopeptidase family protein 0.0042 0.0152 0.0215
Trypanosoma brucei unspecified product 0.004 0.0141 0.138
Echinococcus multilocularis mothers against decapentaplegic 5 0.0032 0.0091 0.0089
Schistosoma mansoni P2X receptor subunit 0.0134 0.0727 0.0994
Echinococcus multilocularis p2X purinoceptor 4 0.0134 0.0727 0.0725
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0103 0.0537 0.0535

Activities

Activity type Activity value Assay description Source Reference
CC50 (functional) = 62 uM Cytotoxicity against human HL60 cells after 48 hrs by MTT assay ChEMBL. 23675651

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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