Detailed information for compound 1788695

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 391.445 | Formula: C21H22FN7
  • H donors: 2 H acceptors: 3 LogP: 2.77 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: N[C@@H]1CC[C@H](CC1)Nc1ccc2n(n1)c(cn2)c1cnn(c1)c1ccc(cc1)F
  • InChi: 1S/C21H22FN7/c22-15-1-7-18(8-2-15)28-13-14(11-25-28)19-12-24-21-10-9-20(27-29(19)21)26-17-5-3-16(23)4-6-17/h1-2,7-13,16-17H,3-6,23H2,(H,26,27)/t16-,17-
  • InChiKey: QEVNEODRZSMEST-QAQDUYKDSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.00326517 0.000848973 0.0318924
Leishmania major hypothetical protein, conserved 0.00326517 0.000848973 0.0297801
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.00326517 0.000848973 0.000219363
Loa Loa (eye worm) hypothetical protein 0.00326517 0.000848973 0.00328961
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0300377 0.02662 0.198756
Schistosoma mansoni serine/threonine protein kinase 0.0151369 0.0122766 0.0360365
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0519862 0.0477473 0.140157
Echinococcus granulosus hexokinase type 2 0.00936069 0.00671645 0.0197154
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.00461835 0.00215153 0.00631556
Echinococcus granulosus Tolloid protein 1 0.00456133 0.00209664 0.00615443
Schistosoma mansoni tyrosine kinase 0.0519862 0.0477473 0.140157
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.00326517 0.000848973 0.00127467
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.00326517 0.000848973 0.0297801
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.135367 0.128009 0.967764
Schistosoma mansoni cercarial elastase (S01 family) 0.00314983 0.000737941 0.00216614
Echinococcus granulosus calcium activated potassium channel 0.00488444 0.00240766 0.0070674
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.00326517 0.000848973 0.00229691
Schistosoma mansoni voltage-gated cation channel 0.00461835 0.00215153 0.00631556
Echinococcus multilocularis carbonic anhydrase II 0.030269 0.0268426 0.0787932
Schistosoma mansoni cercarial elastase (S01 family) 0.00314983 0.000737941 0.00216614
Echinococcus granulosus signal transduction protein lnk realted 0.00665372 0.00411076 0.0120666
Brugia malayi SH2 domain containing protein 0.00665372 0.00411076 0.0108609
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.00665372 0.00411076 0.00337531
Trichomonas vaginalis conserved hypothetical protein 0.0160354 0.0131415 0.0383872
Leishmania major pyruvate dehydrogenase (lipoamide) kinase, putative 0.0118734 0.00913514 0.320441
Trypanosoma cruzi metacaspase 5, putative 0.0160354 0.0131415 0.460975
Brugia malayi cell division control protein 2 homolog 0.0151369 0.0122766 0.03486
Loa Loa (eye worm) hypothetical protein 0.00326517 0.000848973 0.00328961
Echinococcus granulosus retinol dehydrogenase 11 0.00326517 0.000848973 0.00249206
Brugia malayi kinase, mitochondrial precursor 0.0319992 0.0285081 0.0825637
Echinococcus multilocularis carbonyl reductase 1 0.00326517 0.000848973 0.00249206
Loa Loa (eye worm) TK/FER protein kinase 0.00877084 0.00614868 0.0434864
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.00326517 0.000848973 0.0297801
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.00361439 0.00118512 0.000989191
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.00326517 0.000848973 0.000219363
Echinococcus multilocularis cyclins 0.0046965 0.00222675 0.00653636
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.00461835 0.00215153 0.00510284
Loa Loa (eye worm) hypothetical protein 0.00326517 0.000848973 0.00328961
Schistosoma mansoni tensin 0.00665372 0.00411076 0.0120666
Schistosoma mansoni signal transduction protein lnk-related 0.00665372 0.00411076 0.0120666
Toxoplasma gondii calcium binding egf domain-containing protein 0.00415942 0.00170977 0.0642288
Schistosoma mansoni voltage-gated potassium channel 0.00461835 0.00215153 0.00631556
Echinococcus granulosus retinol dehydrogenase 11 0.00326517 0.000848973 0.00249206
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.00326517 0.000848973 0.00127467
Schistosoma mansoni cyclins 0.0046965 0.00222675 0.00653636
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.00326517 0.000848973 0.0241895
Schistosoma mansoni SH2A 0.00665372 0.00411076 0.0120666
Onchocerca volvulus 0.00400784 0.00156385 0.000826524
Trichomonas vaginalis CMGC family protein kinase 0.0151369 0.0122766 0.0358479
Loa Loa (eye worm) hypothetical protein 0.00314983 0.000737941 0.00244747
Trypanosoma cruzi hypothetical protein, conserved 0.00648856 0.00395177 0.138619
Onchocerca volvulus 0.00936069 0.00671645 0.00598293
Echinococcus multilocularis transient receptor potential cation channel 0.00326517 0.000848973 0.00249206
Brugia malayi Variant SH3 domain containing protein 0.00665372 0.00411076 0.0108609
Trypanosoma brucei short-chain dehydrogenase, putative 0.00326517 0.000848973 0.0297801
Echinococcus granulosus cyclin dependent kinase 5 0.0151369 0.0122766 0.0360365
Trypanosoma brucei short-chain dehydrogenase, putative 0.00326517 0.000848973 0.0297801
Echinococcus granulosus caspase 3 0.0539843 0.0496707 0.145802
Schistosoma mansoni alpha-glucosidase 0.116517 0.109864 0.322493
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.00326517 0.000848973 0.000219363
Onchocerca volvulus 0.00326517 0.000848973 0.000111114
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0152594 0.0123945 0.0363826
Loa Loa (eye worm) hypothetical protein 0.0148708 0.0120205 0.0880224
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0160354 0.0131415 0.0383872
Leishmania major hypothetical protein, conserved 0.00326517 0.000848973 0.0297801
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.00461835 0.00215153 0.00631556
Trichomonas vaginalis conserved hypothetical protein 0.00648856 0.00395177 0.0114066
Mycobacterium tuberculosis Probable oxidoreductase 0.528977 0.506894 1
Brugia malayi SH2 domain containing protein 0.00665372 0.00411076 0.0108609
Echinococcus multilocularis retinol dehydrogenase 11 0.00326517 0.000848973 0.00249206
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0519862 0.0477473 0.140157
Plasmodium falciparum hexokinase 0.00936069 0.00671645 0.477178
Loa Loa (eye worm) oxidoreductase 0.00326517 0.000848973 0.00328961
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0433805 0.0394636 0.115841
Schistosoma mansoni hypothetical protein 0.00648856 0.00395177 0.0115999
Onchocerca volvulus 0.00326517 0.000848973 0.000111114
Entamoeba histolytica hexokinase 2 0.00936069 0.00671645 0.19137
Echinococcus multilocularis breast cancer anti estrogen resistance protein 0.00648856 0.00395177 0.0115999
Schistosoma mansoni voltage-gated potassium channel 0.00461835 0.00215153 0.00631556
Toxoplasma gondii oxidoreductase, putative 0.00326517 0.000848973 0.0318924
Brugia malayi Protein kinase domain containing protein 0.00877084 0.00614868 0.0168503
Brugia malayi SH2 domain containing protein 0.00665372 0.00411076 0.0108609
Schistosoma mansoni short chain dehydrogenase 0.00326517 0.000848973 0.00249206
Trichomonas vaginalis cyclin B, putative 0.00918563 0.00654795 0.0190288
Onchocerca volvulus Arrow homolog 0.00453453 0.00207084 0.00133388
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.00326517 0.000848973 0.00249206
Schistosoma mansoni tyrosine kinase 0.0152594 0.0123945 0.0363826
Echinococcus multilocularis nostrin 0.00648856 0.00395177 0.0115999
Loa Loa (eye worm) voltage-gated potassium channel 0.00461835 0.00215153 0.0131692
Echinococcus multilocularis voltage dependent calcium channel 0.00461835 0.00215153 0.00631556
Schistosoma mansoni short chain dehydrogenase 0.00326517 0.000848973 0.00249206
Echinococcus multilocularis Transglutaminase 0.356294 0.340671 1
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.00461835 0.00215153 0.00631556
Trichomonas vaginalis alpha-glucosidase, putative 0.0111875 0.00847494 0.0246864
Echinococcus multilocularis transient receptor potential cation channel 0.00461835 0.00215153 0.00631556
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.00355173 0.00112481 0.00330174
Loa Loa (eye worm) TK/FER protein kinase 0.00877084 0.00614868 0.0434864
Schistosoma mansoni vav2 0.00665372 0.00411076 0.0120666
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.030269 0.0268426 0.941579
Trichomonas vaginalis short-chain dehydrogenase, putative 0.00326517 0.000848973 0.00229691
Brugia malayi Putative carbonic anhydrase 5 precursor 0.030269 0.0268426 0.0776689
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.00326517 0.000848973 0.000219363
Trypanosoma cruzi hypothetical protein, conserved 0.0300377 0.02662 0.933769
Loa Loa (eye worm) hypothetical protein 0.00648856 0.00395177 0.0268235
Loa Loa (eye worm) TK/FER protein kinase 0.00877084 0.00614868 0.0434864
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.00665372 0.00411076 0.0120666
Echinococcus granulosus potassium voltage gated channel protein 0.00461835 0.00215153 0.00631556
Echinococcus multilocularis carbonic anhydrase 0.0170056 0.0140754 0.0413166
Echinococcus multilocularis potassium voltage gated channel protein 0.00461835 0.00215153 0.00631556
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.00461835 0.00215153 0.00612116
Entamoeba histolytica hypothetical protein, conserved 0.00326517 0.000848973 0.0241895
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.00326517 0.000848973 0.00127467
Trypanosoma cruzi metacaspase 5, putative 0.0160354 0.0131415 0.460975
Loa Loa (eye worm) hypothetical protein 0.00582776 0.0033157 0.021999
Echinococcus granulosus transient receptor potential cation channel 0.00461835 0.00215153 0.00631556
Entamoeba histolytica hypothetical protein 0.00648856 0.00395177 0.112597
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.00461835 0.00215153 0.00510284
Loa Loa (eye worm) hypothetical protein 0.00400784 0.00156385 0.0087118
Schistosoma mansoni alpha glucosidase 0.0300377 0.02662 0.0781397
Entamoeba histolytica hexokinase 1 0.00936069 0.00671645 0.19137
Loa Loa (eye worm) TK/FER protein kinase 0.00877084 0.00614868 0.0434864
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.00461835 0.00215153 0.00631556
Echinococcus granulosus tyrosine protein kinase Src42A 0.0433805 0.0394636 0.115841
Brugia malayi prolyl oligopeptidase family protein 0.0230557 0.0198992 0.0572625
Brugia malayi Myosin tail family protein 0.00648856 0.00395177 0.0103937
Echinococcus granulosus epidermal growth factor receptor kinase 0.00648856 0.00395177 0.0115999
Entamoeba histolytica cell division protein kinase 2, putative 0.0151369 0.0122766 0.349793
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0131423 0.0103566 0.0754022
Echinococcus multilocularis potassium voltage gated channel protein 0.00461835 0.00215153 0.00631556
Loa Loa (eye worm) hypothetical protein 0.00665372 0.00411076 0.0280294
Schistosoma mansoni cercarial elastase (S01 family) 0.00314983 0.000737941 0.00216614
Mycobacterium ulcerans transglutaminase family protein 0.356294 0.340671 0.671598
Leishmania major cyclin 0.00918563 0.00654795 0.229687
Trypanosoma brucei metacaspase MCA2 0.0160354 0.0131415 0.460975
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.00461835 0.00215153 0.00612116
Leishmania major hypothetical protein, conserved 0.00326517 0.000848973 0.0297801
Trypanosoma cruzi CYC2-like cyclin, putative 0.00918563 0.00654795 0.229687
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0519862 0.0477473 0.140157
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.00326517 0.000848973 0.0318924
Loa Loa (eye worm) hypothetical protein 0.0170056 0.0140754 0.103608
Brugia malayi Variant SH3 domain containing protein 0.00648856 0.00395177 0.0103937
Loa Loa (eye worm) hypothetical protein 0.00461835 0.00215153 0.0131692
Echinococcus granulosus carbonyl reductase 1 0.00326517 0.000848973 0.00249206
Echinococcus multilocularis cyclins 0.0046965 0.00222675 0.00653636
Schistosoma mansoni cercarial elastase (S01 family) 0.00314983 0.000737941 0.00216614
Trichomonas vaginalis cyclin B, putative 0.0046965 0.00222675 0.006342
Schistosoma mansoni short chain dehydrogenase 0.00326517 0.000848973 0.00249206
Loa Loa (eye worm) SRC-1 0.0519862 0.0477473 0.359001
Loa Loa (eye worm) oxidoreductase 0.00326517 0.000848973 0.00328961
Schistosoma mansoni tyrosine-protein kinase zap-70 0.00665372 0.00411076 0.0120666
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.00324068 0.000825399 0.00242286
Brugia malayi Glycosyl hydrolases family 31 protein 0.0111875 0.00847494 0.0236871
Leishmania major histone deacetylase, putative 0.00582776 0.0033157 0.116307
Echinococcus granulosus caspase 2 0.0988609 0.0928685 0.272604
Echinococcus multilocularis histone deacetylase 6 0.00582776 0.0033157 0.00973283
Mycobacterium ulcerans short chain dehydrogenase 0.00326517 0.000848973 0.000219363
Brugia malayi Variant SH3 domain containing protein 0.00648856 0.00395177 0.0103937
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0111875 0.00847494 0.00774271
Loa Loa (eye worm) hypothetical protein 0.00461835 0.00215153 0.0131692
Schistosoma mansoni hypothetical protein 0.00665372 0.00411076 0.0120666
Loa Loa (eye worm) voltage-gated calcium channel 0.00461835 0.00215153 0.0131692
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.00314983 0.000737941 0.00216614
Brugia malayi dehydrogenases, short chain protein 2 0.00326517 0.000848973 0.00127467
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.00326517 0.000848973 0.00127467
Loa Loa (eye worm) hypothetical protein 0.00293795 0.00053399 0.000900555
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0519862 0.0477473 0.140157
Brugia malayi SH3 domain containing protein 0.00648856 0.00395177 0.0103937
Echinococcus multilocularis sodium channel protein 0.00461835 0.00215153 0.00631556
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.00314983 0.000737941 0.00216614
Trypanosoma cruzi hypothetical protein, conserved 0.0300377 0.02662 0.933769
Onchocerca volvulus Sepiapterin reductase homolog 0.00326517 0.000848973 0.000111114
Toxoplasma gondii hypothetical protein 0.00349638 0.00107153 0.0402527
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.00326517 0.000848973 0.00127467
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0160354 0.0131415 0.493671
Brugia malayi Dehydrogenases, short chain protein 30 0.00326517 0.000848973 0.00127467
Onchocerca volvulus 0.00326517 0.000848973 0.000111114
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.00461835 0.00215153 0.00510284
Schistosoma mansoni voltage-gated potassium channel 0.00461835 0.00215153 0.00631556
Echinococcus granulosus NCK adaptor protein 0.0131423 0.0103566 0.0304005
Echinococcus granulosus Transglutaminase 0.356294 0.340671 1
Brugia malayi Tensin 0.00665372 0.00411076 0.0108609
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.00326517 0.000848973 0.0318924
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0319992 0.0285081 0.083682
Echinococcus granulosus caspase 0.0700197 0.0651063 0.191112
Loa Loa (eye worm) hypothetical protein 0.00461835 0.00215153 0.0131692
Schistosoma mansoni steroid dehydrogenase 0.00326517 0.000848973 0.00249206
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0143229 0.011493 0.0337365
Trypanosoma cruzi hypothetical protein, conserved 0.00326517 0.000848973 0.0297801
Trypanosoma cruzi short chain dehydrogenase, putative 0.00326517 0.000848973 0.0297801
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0170056 0.0140754 0.103608
Echinococcus granulosus voltage dependent calcium channel 0.00461835 0.00215153 0.00631556
Loa Loa (eye worm) hypothetical protein 0.00665372 0.00411076 0.0280294
Schistosoma mansoni C-fyn 0.00648856 0.00395177 0.0115999
Schistosoma mansoni tensin 0.00665372 0.00411076 0.0120666
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.00461835 0.00215153 0.00631556
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.00461835 0.00215153 0.00631556
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.00461835 0.00215153 0.00510284
Echinococcus granulosus carbonyl reductase 1 0.00326517 0.000848973 0.00249206
Trypanosoma cruzi hypothetical protein, conserved 0.0106696 0.00797645 0.279796
Brugia malayi Transient-receptor-potential like protein 0.00461835 0.00215153 0.00510284
Schistosoma mansoni steroid dehydrogenase 0.00326517 0.000848973 0.00249206
Echinococcus multilocularis carbonic anhydrase 0.0170056 0.0140754 0.0413166
Loa Loa (eye worm) hypothetical protein 0.00326517 0.000848973 0.00328961
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.00326517 0.000848973 0.00249206
Loa Loa (eye worm) TK/FER protein kinase 0.00877084 0.00614868 0.0434864
Schistosoma mansoni short chain dehydrogenase 0.00326517 0.000848973 0.00249206
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0170056 0.0140754 0.0401465
Echinococcus multilocularis laminin 0.00415942 0.00170977 0.00501882
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.00326517 0.000848973 0.0603162
Brugia malayi Cyclin, N-terminal domain containing protein 0.00918563 0.00654795 0.0180237
Loa Loa (eye worm) hypothetical protein 0.00918563 0.00654795 0.0465148
Trichomonas vaginalis conserved hypothetical protein 0.00648856 0.00395177 0.0114066
Trichomonas vaginalis short-chain dehydrogenase, putative 0.00326517 0.000848973 0.00229691
Echinococcus granulosus tyrosine protein kinase Fyn 0.0519862 0.0477473 0.140157
Schistosoma mansoni cell polarity protein 0.00648856 0.00395177 0.0115999
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0700197 0.0651063 0.191112
Echinococcus multilocularis suppressor of cytokine signaling 6 0.00665372 0.00411076 0.0120666
Trichomonas vaginalis alpha-glucosidase, putative 0.0300377 0.02662 0.0779594
Echinococcus multilocularis potassium voltage gated channel protein 0.00461835 0.00215153 0.00631556
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.00314983 0.000737941 0.00216614
Echinococcus granulosus potassium large conductance calcium activated 0.00461835 0.00215153 0.00631556
Echinococcus multilocularis cyclins 0.0046965 0.00222675 0.00653636
Echinococcus multilocularis calcium activated potassium channel 0.00488444 0.00240766 0.0070674
Leishmania major carbonic anhydrase-like protein 0.030269 0.0268426 0.941579
Mycobacterium ulcerans short-chain dehydrogenase 0.00326517 0.000848973 0.000219363
Echinococcus multilocularis hyperpolarization activated cyclic 0.00461835 0.00215153 0.00631556
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.00461835 0.00215153 0.00631556
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.00326517 0.000848973 0.00229691
Trypanosoma cruzi oxidoreductase-like protein, putative 0.00326517 0.000848973 0.0297801
Echinococcus granulosus transient receptor potential cation channel 0.00461835 0.00215153 0.00631556
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0151369 0.0122766 0.430636
Loa Loa (eye worm) hypothetical protein 0.00461835 0.00215153 0.0131692
Loa Loa (eye worm) hypothetical protein 0.0131423 0.0103566 0.0754022
Brugia malayi Fibulin-1 precursor 0.00415942 0.00170977 0.00380452
Entamoeba histolytica hypothetical protein, conserved 0.00648856 0.00395177 0.112597
Trypanosoma brucei hexokinase 0.00936069 0.00671645 0.235598
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0300377 0.02662 0.758474
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.00461835 0.00215153 0.00510284
Loa Loa (eye worm) hypothetical protein 0.00461835 0.00215153 0.0131692
Echinococcus multilocularis oxidoreductase 0.00326517 0.000848973 0.00249206
Echinococcus granulosus tyrosine protein kinase Blk 0.0454976 0.0415015 0.121823
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.00326517 0.000848973 0.000219363
Plasmodium falciparum metacaspase-like protein 0.0160354 0.0131415 0.933652
Echinococcus granulosus histone deacetylase 6 0.00582776 0.0033157 0.00973283
Echinococcus multilocularis suppressor of cytokine signaling 7 0.00665372 0.00411076 0.0120666
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.00461835 0.00215153 0.00141463
Brugia malayi Cyclic-nucleotide gated cation channel 0.00461835 0.00215153 0.00510284
Trichomonas vaginalis alpha-glucosidase, putative 0.0111875 0.00847494 0.0246864
Echinococcus granulosus transient receptor potential gamma protein 0.00461835 0.00215153 0.00631556
Trichomonas vaginalis alpha-glucosidase, putative 0.0111875 0.00847494 0.0246864
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0151369 0.0122766 0.089965
Toxoplasma gondii transporter, cation channel family protein 0.00461835 0.00215153 0.080824
Loa Loa (eye worm) protein kinase C and casein kinase substrate in neurons protein 2 0.00648856 0.00395177 0.0268235
Brugia malayi hexokinase 0.00936069 0.00671645 0.018519
Brugia malayi hypothetical protein 0.00314983 0.000737941 0.000948355
Giardia lamblia Cyclin A 0.0046965 0.00222675 0.00405441
Echinococcus granulosus WW domain containing oxidoreductase 0.00326517 0.000848973 0.00249206
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0230557 0.0198992 0.0584116
Leishmania major quinonoid dihydropteridine reductase 0.00326517 0.000848973 0.0297801
Loa Loa (eye worm) hypothetical protein 0.00456133 0.00209664 0.0127528
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0170056 0.0140754 0.0401465
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0131423 0.0103566 0.0304005
Loa Loa (eye worm) hypothetical protein 0.00665372 0.00411076 0.0280294
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.00326517 0.000848973 0.00127467
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.00326517 0.000848973 0.000219363
Echinococcus granulosus potassium voltage gated channel subfamily H 0.00461835 0.00215153 0.00631556
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0139923 0.0111748 0.0328024
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.00461835 0.00215153 0.00631556
Loa Loa (eye worm) hypothetical protein 0.00448913 0.00202714 0.0122257
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.00326517 0.000848973 0.000219363
Echinococcus granulosus potassium voltage gated channel subfamily D 0.00461835 0.00215153 0.00631556
Loa Loa (eye worm) hypothetical protein 0.00314983 0.000737941 0.00244747
Trichomonas vaginalis short-chain dehydrogenase, putative 0.00326517 0.000848973 0.00229691
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.00665372 0.00411076 0.0120666
Echinococcus granulosus hyperpolarization activated cyclic 0.00461835 0.00215153 0.00631556
Brugia malayi Muscle positioning protein 4 0.00419834 0.00174723 0.00391461
Echinococcus multilocularis sodium leak channel non selective protein 0.00461835 0.00215153 0.00631556
Echinococcus multilocularis histone deacetylase 6 0.00582776 0.0033157 0.00973283
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0300377 0.02662 0.0779594
Onchocerca volvulus Putative cortactin 0.00648856 0.00395177 0.0032162
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0143229 0.011493 0.403151
Schistosoma mansoni adapter molecule crk 0.0131423 0.0103566 0.0304005
Toxoplasma gondii hypothetical protein 0.00461835 0.00215153 0.080824
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.00461835 0.00215153 0.0754709
Echinococcus multilocularis cyclins 0.0046965 0.00222675 0.00653636
Brugia malayi hypothetical protein 0.00326517 0.000848973 0.00127467
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.00326517 0.000848973 0.0297801
Brugia malayi Histone deacetylase family protein 0.00582776 0.0033157 0.00852428
Echinococcus granulosus oxidoreductase 0.00326517 0.000848973 0.00249206
Schistosoma mansoni tyrosine kinase 0.0519862 0.0477473 0.140157
Trypanosoma brucei cdc2-related kinase 3 0.0151369 0.0122766 0.430636
Loa Loa (eye worm) hypothetical protein 0.00776969 0.00518498 0.036177
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.00326517 0.000848973 0.00249206
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.00314983 0.000737941 0.00216614
Entamoeba histolytica hypothetical protein, conserved 0.00326517 0.000848973 0.0241895
Trichomonas vaginalis cyclins, putative 0.00918563 0.00654795 0.0190288
Echinococcus multilocularis tensin 0.00665372 0.00411076 0.0120666
Trypanosoma cruzi hypothetical protein, conserved 0.00648856 0.00395177 0.138619
Echinococcus granulosus Spectrin alpha actinin 0.00648856 0.00395177 0.0115999
Loa Loa (eye worm) hypothetical protein 0.00461835 0.00215153 0.0131692
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.00326517 0.000848973 0.00328961
Brugia malayi STAT protein, DNA binding domain containing protein 0.00665372 0.00411076 0.0108609
Entamoeba histolytica hypothetical protein 0.00648856 0.00395177 0.112597
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0160354 0.0131415 0.0383872
Trichomonas vaginalis conserved hypothetical protein 0.0160354 0.0131415 0.0383872
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.00361439 0.00118512 0.000664268
Schistosoma mansoni cyclin B3 0.0139923 0.0111748 0.0328024
Loa Loa (eye worm) hypothetical protein 0.00415942 0.00170977 0.00981852
Trichomonas vaginalis conserved hypothetical protein 0.0160354 0.0131415 0.0383872
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.00326517 0.000848973 0.0241895
Echinococcus multilocularis transfer RNA-Gly 0.00461835 0.00215153 0.00631556
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0160354 0.0131415 0.0383872
Loa Loa (eye worm) hypothetical protein 0.00466661 0.00219799 0.0135215
Echinococcus granulosus suppressor of cytokine signaling 6 0.00665372 0.00411076 0.0120666
Trypanosoma brucei hexokinase, putative 0.00936069 0.00671645 0.235598
Mycobacterium ulcerans short chain dehydrogenase 0.00326517 0.000848973 0.000219363
Echinococcus granulosus hypothetical protein 0.00461835 0.00215153 0.00631556
Schistosoma mansoni hypothetical protein 0.00314983 0.000737941 0.00216614
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.00314983 0.000737941 0.00216614
Echinococcus multilocularis caspase 0.0700197 0.0651063 0.191112
Echinococcus multilocularis tyrosine protein kinase Blk 0.0454976 0.0415015 0.121823
Loa Loa (eye worm) SH2 domain-containing protein 0.00665372 0.00411076 0.0280294
Brugia malayi protein-tyrosine kinase 0.0454976 0.0415015 0.120751
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.00665372 0.00411076 0.0120666
Schistosoma mansoni nck2/grb4 0.0131423 0.0103566 0.0304005
Trichomonas vaginalis conserved hypothetical protein 0.0046965 0.00222675 0.006342
Echinococcus granulosus short transient receptor potential channel 6 0.00462401 0.00215698 0.00633154
Brugia malayi Glycosyl hydrolases family 31 protein 0.135367 0.128009 0.374993
Onchocerca volvulus 0.068911 0.064039 0.0633479
Brugia malayi Trypsin-like protease protein 5 0.00314983 0.000737941 0.000948355
Brugia malayi SRC-1 0.0519862 0.0477473 0.139107
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.00461835 0.00215153 0.00631556
Echinococcus multilocularis hexokinase 0.00936069 0.00671645 0.0197154
Leishmania major histone deacetylase, putative 0.00582776 0.0033157 0.116307
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.00326517 0.000848973 0.0297801
Trichomonas vaginalis neutrophil cytosolic factor 2, neutrophil NADPH oxidase factor, putative 0.00648856 0.00395177 0.0114066
Mycobacterium tuberculosis Long conserved protein 0.356294 0.340671 0.671526
Entamoeba histolytica protein kinase, putative 0.00648856 0.00395177 0.112597
Echinococcus granulosus hypothetical protein 0.00326517 0.000848973 0.00249206
Echinococcus granulosus cyclin b3 0.0046965 0.00222675 0.00653636
Schistosoma mansoni pyruvate dehydrogenase 0.0302779 0.0268512 0.0788184
Loa Loa (eye worm) STAT protein 0.00665372 0.00411076 0.0280294
Loa Loa (eye worm) hypothetical protein 0.00665372 0.00411076 0.0280294
Echinococcus multilocularis Tolloid protein 1 0.00456133 0.00209664 0.00615443
Mycobacterium leprae Conserved hypothetical protein 0.356294 0.340671 1
Onchocerca volvulus 0.00665372 0.00411076 0.00337531
Echinococcus granulosus rho guanine nucleotide exchange factor 7 0.00648856 0.00395177 0.0115999
Schistosoma mansoni voltage-gated potassium channel 0.00461835 0.00215153 0.00631556
Schistosoma mansoni hexokinase 0.00936069 0.00671645 0.0197154
Loa Loa (eye worm) ion channel NompC 0.00461835 0.00215153 0.0131692
Echinococcus multilocularis SH2 domain containing protein 7 0.00665372 0.00411076 0.0120666
Trichomonas vaginalis cyclin D, putative 0.0046965 0.00222675 0.006342
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.00461835 0.00215153 0.00510284
Brugia malayi Tyrosine-protein kinase abl-1 0.0809189 0.0755977 0.220959
Leishmania major hexokinase, putative 0.00936069 0.00671645 0.235598
Echinococcus multilocularis hyperpolarization activated cyclic 0.00461835 0.00215153 0.00631556
Echinococcus multilocularis tyrosine protein kinase Srms 0.0454976 0.0415015 0.121823
Mycobacterium ulcerans short chain dehydrogenase 0.00326517 0.000848973 0.000219363
Schistosoma mansoni voltage-gated potassium channel 0.00461835 0.00215153 0.00631556
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.00326517 0.000848973 0.000219363
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.00648856 0.00395177 0.0115999
Echinococcus multilocularis NCK adaptor protein 0.0131423 0.0103566 0.0304005
Echinococcus multilocularis glycoprotein Antigen 5 0.00314983 0.000737941 0.00216614
Loa Loa (eye worm) hexokinase type II 0.00936069 0.00671645 0.0477928
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.00461835 0.00215153 0.00631556
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.00665372 0.00411076 0.0120666
Mycobacterium ulcerans short-chain dehydrogenase 0.00326517 0.000848973 0.000219363
Mycobacterium tuberculosis Conserved hypothetical protein 0.356294 0.340671 0.671526
Loa Loa (eye worm) hypothetical protein 0.0106696 0.00797645 0.0573495
Echinococcus multilocularis plexin a4 0.00477216 0.00229959 0.00675016
Schistosoma mansoni short chain dehydrogenase 0.00326517 0.000848973 0.00249206
Echinococcus granulosus glycoprotein Antigen 5 0.00314983 0.000737941 0.00216614
Trypanosoma brucei mitotic cyclin 6 0.00918563 0.00654795 0.229687
Echinococcus multilocularis carbonyl reductase 1 0.00326517 0.000848973 0.00249206
Onchocerca volvulus 0.00665372 0.00411076 0.00337531
Echinococcus granulosus intersectin 2 0.00648856 0.00395177 0.0115999
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0519862 0.0477473 0.140157
Entamoeba histolytica hypothetical protein 0.00648856 0.00395177 0.112597
Loa Loa (eye worm) hypothetical protein 0.00453453 0.00207084 0.0125571
Mycobacterium ulcerans oxidoreductase 0.00326517 0.000848973 0.000219363
Echinococcus granulosus cyclins 0.0046965 0.00222675 0.00653636
Echinococcus granulosus two pore calcium channel protein 1 0.00461835 0.00215153 0.00631556
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0143229 0.011493 0.403151
Mycobacterium leprae Conserved hypothetical protein 0.356294 0.340671 1
Echinococcus granulosus tensin 0.00665372 0.00411076 0.0120666
Echinococcus granulosus potassium voltage gated channel subfamily A 0.00461835 0.00215153 0.00631556
Loa Loa (eye worm) TK/KIN16 protein kinase 0.010313 0.00763312 0.0547455
Loa Loa (eye worm) hypothetical protein 0.00461835 0.00215153 0.0131692
Brugia malayi olfactory channel protein osm-9 0.00462401 0.00215698 0.00511885
Trypanosoma cruzi hypothetical protein, conserved 0.00648856 0.00395177 0.138619
Trichomonas vaginalis peptide N-glycanase, putative 0.356294 0.340671 1
Entamoeba histolytica hypothetical protein 0.00648856 0.00395177 0.112597
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.00877084 0.00614868 0.0180487
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0300377 0.02662 0.0779594
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.00461835 0.00215153 0.00510284
Entamoeba histolytica SH2 domain containing protein 0.00665372 0.00411076 0.117127
Echinococcus multilocularis caspase 8 0.0160354 0.0131415 0.0385753
Echinococcus granulosus tyrosine protein kinase Fyn 0.0519862 0.0477473 0.140157
Plasmodium vivax histone deacetylase 2, putative 0.00582776 0.0033157 0.200669
Plasmodium falciparum steroid dehydrogenase, putative 0.00326517 0.000848973 0.0603162
Giardia lamblia Kinase, CMGC CDK 0.0151369 0.0122766 0.0336282
Schistosoma mansoni hypothetical protein 0.00461835 0.00215153 0.00631556
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0143229 0.011493 0.0337365
Echinococcus multilocularis lysosomal alpha glucosidase 0.135367 0.128009 0.375755
Trypanosoma brucei histone deacetylase, putative 0.00582776 0.0033157 0.116307
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.00326517 0.000848973 0.000111114
Schistosoma mansoni transient receptor potential channel 0.00461835 0.00215153 0.00631556
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.00665372 0.00411076 0.0120666
Loa Loa (eye worm) RhoGAP domain-containing protein 0.00665372 0.00411076 0.0280294
Echinococcus multilocularis steroid dehydrogenase 0.00326517 0.000848973 0.00249206
Schistosoma mansoni voltage-gated potassium channel 0.00461835 0.00215153 0.00631556
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0160354 0.0131415 0.0383872
Onchocerca volvulus 0.00575255 0.0032433 0.00250721
Mycobacterium ulcerans putative transglutaminase-like protein 0.356294 0.340671 0.671598
Echinococcus multilocularis transient receptor potential cation channel 0.00462401 0.00215698 0.00633154
Echinococcus granulosus TRP transient receptor potential channel 0.00461835 0.00215153 0.00631556
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.00326517 0.000848973 0.0241895
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0160354 0.0131415 0.0383872
Brugia malayi RhoGAP domain containing protein 0.00665372 0.00411076 0.0108609
Leishmania major glycosyl hydrolase-like protein 0.0111875 0.00847494 0.297282
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.00326517 0.000848973 0.0297801
Schistosoma mansoni short chain dehydrogenase 0.00326517 0.000848973 0.00249206
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.00461835 0.00215153 0.0754709
Giardia lamblia Transglutaminase/protease, putative 0.356294 0.340671 1
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.00461835 0.00215153 0.00631556
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0152594 0.0123945 0.0363826
Echinococcus multilocularis transient receptor potential cation channel 0.00461835 0.00215153 0.00631556
Echinococcus granulosus cyclin B 0.00918563 0.00654795 0.0192207
Trypanosoma cruzi short-chain dehydrogenase, putative 0.00326517 0.000848973 0.0297801
Trichomonas vaginalis p67phox protein, putative 0.00648856 0.00395177 0.0114066
Brugia malayi dehydrogenases, short chain protein 9 0.00326517 0.000848973 0.00127467
Trypanosoma cruzi cyclin 6, putative 0.00918563 0.00654795 0.229687
Brugia malayi SH2 domain containing protein 0.00665372 0.00411076 0.0108609
Echinococcus granulosus tissue type plasminogen activator 0.0106696 0.00797645 0.0234139
Echinococcus granulosus slit robo rho gtpase activating protein 1 0.00648856 0.00395177 0.0115999
Leishmania major quinonoid dihydropteridine reductase 0.00326517 0.000848973 0.0297801
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.030269 0.0268426 0.0787932
Echinococcus granulosus hypothetical protein 0.00665372 0.00411076 0.0120666
Schistosoma mansoni short chain dehydrogenase 0.00326517 0.000848973 0.00249206
Leishmania major hypothetical protein, conserved 0.00326517 0.000848973 0.0297801
Echinococcus multilocularis cyclin b3 0.0046965 0.00222675 0.00653636
Schistosoma mansoni cercarial elastase (S01 family) 0.00314983 0.000737941 0.00216614
Trypanosoma brucei short-chain dehydrogenase, putative 0.00326517 0.000848973 0.0297801
Schistosoma mansoni sh3-containing grb2-like protein 1 (endophilin II) 0.00648856 0.00395177 0.0115999
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.00326517 0.000848973 0.00127467
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.00314983 0.000737941 0.00216614
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.00314983 0.000737941 0.00216614
Echinococcus multilocularis intersectin 2 0.00648856 0.00395177 0.0115999
Echinococcus multilocularis epidermal growth factor receptor kinase 0.00648856 0.00395177 0.0115999
Echinococcus multilocularis expressed protein 0.00648856 0.00395177 0.0115999
Echinococcus granulosus tyrosine protein kinase Src64B 0.0519862 0.0477473 0.140157
Onchocerca volvulus 0.0782929 0.0730699 0.0723854
Trichomonas vaginalis conserved hypothetical protein 0.00648856 0.00395177 0.0114066
Onchocerca volvulus Hexokinase homolog 0.00575255 0.0032433 0.00250721
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0519862 0.0477473 0.140157
Schistosoma mansoni hypothetical protein 0.356294 0.340671 1
Plasmodium falciparum cyclin 0.0046965 0.00222675 0.158202
Schistosoma mansoni hypothetical protein 0.0570752 0.052646 0.154536
Loa Loa (eye worm) hypothetical protein 0.0522098 0.0479626 0.360633
Echinococcus granulosus tensin C1 domain containing phosphatase 0.00665372 0.00411076 0.0120666
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.00326517 0.000848973 0.00249206
Trypanosoma brucei short-chain dehydrogenase, putative 0.00326517 0.000848973 0.0297801
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.00987291 0.00720952 0.270831
Loa Loa (eye worm) protein-tyrosine kinase 0.00648856 0.00395177 0.0268235
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.00314983 0.000737941 0.00216614
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0160354 0.0131415 0.0383872
Loa Loa (eye worm) hypothetical protein 0.00665372 0.00411076 0.0280294
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.00456133 0.00209664 0.00615443
Leishmania major short chain dehydrogenase-like protein 0.00326517 0.000848973 0.0297801
Loa Loa (eye worm) histone deacetylase 7A 0.00582776 0.0033157 0.021999
Echinococcus multilocularis tyrosine protein kinase shark 0.0087765 0.00615412 0.0180647
Entamoeba histolytica cell division protein kinase 2, putative 0.0151369 0.0122766 0.349793
Trypanosoma brucei hexokinase 0.00936069 0.00671645 0.235598
Mycobacterium ulcerans short chain dehydrogenase 0.00326517 0.000848973 0.000219363
Brugia malayi Protein kinase domain containing protein 0.0127868 0.0100144 0.0282114
Plasmodium vivax hexokinase, putative 0.00936069 0.00671645 0.477321
Schistosoma mansoni steroid dehydrogenase 0.00326517 0.000848973 0.00249206
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0170056 0.0140754 0.0401465
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.00648856 0.00395177 0.0115999
Schistosoma mansoni calcium-activated potassium channel 0.00461835 0.00215153 0.00631556
Loa Loa (eye worm) oxidoreductase 0.00326517 0.000848973 0.00328961
Schistosoma mansoni growth factor receptor-bound protein 0.0131423 0.0103566 0.0304005
Schistosoma mansoni serine/threonine protein kinase 0.00860568 0.00598969 0.017582
Schistosoma mansoni tensin-related 0.00665372 0.00411076 0.0120666
Brugia malayi tRNA modification GTPase TrmE family protein 0.00665372 0.00411076 0.0108609
Loa Loa (eye worm) dehydrogenase 0.00326517 0.000848973 0.00328961
Toxoplasma gondii oxidoreductase, putative 0.00326517 0.000848973 0.0318924
Echinococcus granulosus transient receptor potential cation channel 0.00461835 0.00215153 0.00631556
Loa Loa (eye worm) cyclin domain-containing protein 0.0139923 0.0111748 0.0816085
Schistosoma mansoni eps8-related protein 0.00648856 0.00395177 0.0115999
Schistosoma mansoni transient receptor potential channel 0.00461835 0.00215153 0.00631556
Loa Loa (eye worm) hypothetical protein 0.00314983 0.000737941 0.00244747
Echinococcus multilocularis two pore calcium channel protein 2 0.00461835 0.00215153 0.00631556
Brugia malayi protein-tyrosine kinase 0.00648856 0.00395177 0.0103937
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.00326517 0.000848973 0.0318924
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.00326517 0.000848973 0.00127467
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.00326517 0.000848973 0.00127467
Trypanosoma cruzi short chain dehydrogenase, putative 0.00326517 0.000848973 0.0297801
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0106696 0.00797645 0.579822
Echinococcus multilocularis tensin 0.00665372 0.00411076 0.0120666
Echinococcus multilocularis rho guanine nucleotide exchange factor 7 0.00648856 0.00395177 0.0115999
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.00326517 0.000848973 0.000111114
Toxoplasma gondii carbonyl reductase 1, putative 0.00326517 0.000848973 0.0318924
Echinococcus granulosus carbonic anhydrase II 0.030269 0.0268426 0.0787932
Brugia malayi Trypsin family protein 0.00314983 0.000737941 0.000948355
Entamoeba histolytica unconventional myosin IB 0.00648856 0.00395177 0.112597
Echinococcus multilocularis cyclins 0.0046965 0.00222675 0.00653636
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.00324068 0.000825399 0.00242286
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.00461835 0.00215153 0.00631556
Entamoeba histolytica hypothetical protein, conserved 0.00648856 0.00395177 0.112597
Loa Loa (eye worm) hypothetical protein 0.00648856 0.00395177 0.0268235
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.00415942 0.00170977 0.00981852
Echinococcus multilocularis cyclins 0.0046965 0.00222675 0.00653636
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.00461835 0.00215153 0.00631556
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.00665372 0.00411076 0.0280294
Trypanosoma cruzi hypothetical protein, conserved 0.00326517 0.000848973 0.0297801
Echinococcus granulosus hyperpolarization activated cyclic 0.00461835 0.00215153 0.00631556
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0151369 0.0122766 0.089965
Echinococcus granulosus transient receptor potential cation channel 0.00462401 0.00215698 0.00633154
Loa Loa (eye worm) hypothetical protein 0.00665372 0.00411076 0.0280294
Mycobacterium ulcerans short chain dehydrogenase 0.00326517 0.000848973 0.000219363
Brugia malayi cation channel family protein 0.00461835 0.00215153 0.00510284
Loa Loa (eye worm) hypothetical protein 0.0988609 0.0928685 0.701232
Echinococcus multilocularis SHC transforming protein 3 0.00665372 0.00411076 0.0120666
Schistosoma mansoni cercarial elastase (S01 family) 0.00314983 0.000737941 0.00216614
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.00461835 0.00215153 0.00631556
Loa Loa (eye worm) hexokinase 0.00936069 0.00671645 0.0477928
Echinococcus multilocularis retinol dehydrogenase 13 0.00326517 0.000848973 0.00249206
Loa Loa (eye worm) hypothetical protein 0.00582776 0.0033157 0.021999
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.00326517 0.000848973 0.000219363
Brugia malayi Cyclin, N-terminal domain containing protein 0.00918563 0.00654795 0.0180237
Echinococcus granulosus carbonyl reductase 1 0.00326517 0.000848973 0.00249206
Loa Loa (eye worm) hypothetical protein 0.00461835 0.00215153 0.0131692
Schistosoma mansoni shc transforming protein 0.00665372 0.00411076 0.0120666
Loa Loa (eye worm) voltage-gated potassium channel 0.00461835 0.00215153 0.0131692
Echinococcus granulosus short transient receptor potential channel 6 0.00461835 0.00215153 0.00631556
Toxoplasma gondii pyruvate dehydrogenase kinase, putative 0.0118734 0.00913514 0.343169
Schistosoma mansoni signal transducing adapter molecule (stam) 0.00648856 0.00395177 0.0115999
Echinococcus multilocularis short transient receptor potential channel 6 0.00461835 0.00215153 0.00631556
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.00326517 0.000848973 0.00127467
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0319992 0.0285081 0.083682
Trypanosoma cruzi histone deacetylase, putative 0.00582776 0.0033157 0.116307
Schistosoma mansoni histone deacetylase 4 5 0.00582776 0.0033157 0.00973283
Echinococcus granulosus voltage gated hydrogen channel 1 0.00461835 0.00215153 0.00631556
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.00461835 0.00215153 0.00631556
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.00326517 0.000848973 0.00127467
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.00461835 0.00215153 0.00510284
Schistosoma mansoni cyclin B 0.00918563 0.00654795 0.0192207
Onchocerca volvulus 0.00326517 0.000848973 0.000111114
Schistosoma mansoni sorbin 0.00648856 0.00395177 0.0115999
Onchocerca volvulus 0.00675464 0.0042079 0.00347252
Echinococcus granulosus tyrosine protein kinase Fyn 0.0519862 0.0477473 0.140157
Loa Loa (eye worm) hypothetical protein 0.00648856 0.00395177 0.0268235
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0519862 0.0477473 0.140157
Schistosoma mansoni caspase-3 (C14 family) 0.0700197 0.0651063 0.191112
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.00461835 0.00215153 0.080824
Echinococcus granulosus potassium voltage gated channel subfamily D 0.00461835 0.00215153 0.00631556
Echinococcus multilocularis cyclin dependent kinase 1 0.0151369 0.0122766 0.0360365
Entamoeba histolytica cyclin family protein 0.0046965 0.00222675 0.0634461
Onchocerca volvulus 0.0106696 0.00797645 0.00724385
Onchocerca volvulus 0.00665372 0.00411076 0.00337531
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.00461835 0.00215153 0.00510284
Echinococcus multilocularis SH2 motif 0.00665372 0.00411076 0.0120666
Loa Loa (eye worm) hypothetical protein 0.00877084 0.00614868 0.0434864
Onchocerca volvulus 0.00326517 0.000848973 0.000111114
Echinococcus multilocularis tyrosine protein kinase Abl 0.0653521 0.0606132 0.177923
Trypanosoma brucei histone deacetylase 3 0.00582776 0.0033157 0.116307
Leishmania major oxidoreductase-like protein 0.00326517 0.000848973 0.0297801
Echinococcus multilocularis retinol dehydrogenase 11 0.00326517 0.000848973 0.00249206
Loa Loa (eye worm) hypothetical protein 0.00314983 0.000737941 0.00244747
Schistosoma mansoni short chain dehydrogenase 0.00326517 0.000848973 0.00249206
Schistosoma mansoni short chain dehydrogenase 0.00326517 0.000848973 0.00249206
Loa Loa (eye worm) trypsin family protein 0.00314983 0.000737941 0.00244747
Brugia malayi Variant SH3 domain containing protein 0.00665372 0.00411076 0.0108609
Entamoeba histolytica short chain dehydrogenase family protein 0.00326517 0.000848973 0.0241895
Echinococcus multilocularis Mastin 0.00314983 0.000737941 0.00216614
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.00326517 0.000848973 0.0297801
Schistosoma mansoni hypothetical protein 0.00314983 0.000737941 0.00216614
Mycobacterium ulcerans short chain dehydrogenase 0.00326517 0.000848973 0.000219363
Loa Loa (eye worm) guanylate kinase 0.00648856 0.00395177 0.0268235
Toxoplasma gondii hypothetical protein 0.0170056 0.0140754 0.528752
Loa Loa (eye worm) TK protein kinase 0.0454976 0.0415015 0.311628
Echinococcus granulosus cyclin dependent kinase 1 0.0151369 0.0122766 0.0360365
Loa Loa (eye worm) hypothetical protein 0.068911 0.064039 0.482569
Echinococcus multilocularis cyclin B3 1 0.0046965 0.00222675 0.00653636
Onchocerca volvulus 0.00326517 0.000848973 0.000111114
Plasmodium vivax metacaspase 1, putative 0.0160354 0.0131415 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0160354 0.0131415 0.0383872
Schistosoma mansoni tensin 0.00665372 0.00411076 0.0120666
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.00461835 0.00215153 0.0131692
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.00326517 0.000848973 0.00127467
Trypanosoma brucei metacaspase 0.0160354 0.0131415 0.460975
Mycobacterium ulcerans short chain dehydrogenase 0.00326517 0.000848973 0.000219363
Echinococcus multilocularis transient receptor potential cation channel 0.00461835 0.00215153 0.00631556
Mycobacterium ulcerans dehydrogenase/reductase 0.00326517 0.000848973 0.000219363
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0160354 0.0131415 0.493671
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.00461835 0.00215153 0.00631556
Echinococcus granulosus src region 0.00648856 0.00395177 0.0115999
Giardia lamblia Kinase, CMGC CDK 0.0151369 0.0122766 0.0336282
Schistosoma mansoni histone deacetylase hda2 0.00582776 0.0033157 0.00973283
Echinococcus multilocularis c src tyrosine kinase 0.0152594 0.0123945 0.0363826
Loa Loa (eye worm) hypothetical protein 0.00648856 0.00395177 0.0268235
Trypanosoma cruzi metacaspase, putative 0.0160354 0.0131415 0.460975
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.00326517 0.000848973 0.000219363
Echinococcus granulosus tyrosine protein kinase shark 0.0087765 0.00615412 0.0180647
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.00326517 0.000848973 0.0297801
Loa Loa (eye worm) hypothetical protein 0.00648856 0.00395177 0.0268235
Echinococcus granulosus cyclin B3 1 0.0046965 0.00222675 0.00653636
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0182414 0.015265 0.0448085
Schistosoma mansoni voltage-gated potassium channel 0.00461835 0.00215153 0.00631556
Loa Loa (eye worm) oxidoreductase 0.00326517 0.000848973 0.00328961
Brugia malayi cation channel family protein 0.00461835 0.00215153 0.00510284
Trichomonas vaginalis short-chain dehydrogenase, putative 0.00326517 0.000848973 0.00229691
Trypanosoma cruzi pyruvate dehydrogenase (lipoamide) kinase, putative 0.0118734 0.00913514 0.320441
Loa Loa (eye worm) hypothetical protein 0.00326517 0.000848973 0.00328961
Trichomonas vaginalis sucrase-isomaltase, putative 0.0300377 0.02662 0.0779594
Schistosoma mansoni retinal dehydrogenase 0.00326517 0.000848973 0.00249206
Trichomonas vaginalis conserved hypothetical protein 0.00648856 0.00395177 0.0114066
Echinococcus granulosus two pore calcium channel protein 2 0.00461835 0.00215153 0.00631556
Echinococcus multilocularis caspase 3 0.0539843 0.0496707 0.145802
Onchocerca volvulus 0.00918563 0.00654795 0.0058143
Loa Loa (eye worm) hypothetical protein 0.00461835 0.00215153 0.0131692
Trypanosoma cruzi histone deacetylase, putative 0.00582776 0.0033157 0.116307
Onchocerca volvulus 0.00326517 0.000848973 0.000111114
Loa Loa (eye worm) hypothetical protein 0.0160354 0.0131415 0.096525
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.00326517 0.000848973 0.00127467
Trichomonas vaginalis cyclins, putative 0.0046965 0.00222675 0.006342
Trypanosoma brucei metacaspase 5, putative 0.0160354 0.0131415 0.460975
Schistosoma mansoni voltage-gated potassium channel 0.00461835 0.00215153 0.00631556
Schistosoma mansoni carbonic anhydrase-related 0.0170056 0.0140754 0.0413166
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.00314983 0.000737941 0.000948355
Plasmodium falciparum cysteine repeat modular protein 1 0.0106696 0.00797645 0.566695
Loa Loa (eye worm) hexokinase 0.00936069 0.00671645 0.0477928
Mycobacterium ulcerans short chain dehydrogenase 0.00326517 0.000848973 0.000219363
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.00461835 0.00215153 0.080824
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.00326517 0.000848973 0.0318924
Echinococcus multilocularis SH2 motif 0.00665372 0.00411076 0.0120666
Trichomonas vaginalis cyclin B, putative 0.00918563 0.00654795 0.0190288
Schistosoma mansoni steroid dehydrogenase 0.00326517 0.000848973 0.00249206
Echinococcus multilocularis apoptotic protease activating factor 1 0.068911 0.064039 0.187979
Brugia malayi hypothetical protein 0.068911 0.064039 0.186988
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.00326517 0.000848973 0.5
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.00665372 0.00411076 0.0120666
Brugia malayi Variant SH3 domain containing protein 0.0131423 0.0103566 0.0292172
Brugia malayi prolyl oligopeptidase family protein 0.0143229 0.011493 0.0325572
Echinococcus granulosus retinoic acid receptor rxr beta a 0.00519243 0.00270413 0.00793767
Echinococcus granulosus hexokinase 0.00936069 0.00671645 0.0197154
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.00461835 0.00215153 0.0131692
Trypanosoma brucei glycosyl hydrolase-like protein 0.0111875 0.00847494 0.297282
Mycobacterium ulcerans carveol-like dehydrogenase 0.00326517 0.000848973 0.000219363
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.00326517 0.000848973 0.0241895
Brugia malayi Histone deacetylase family protein 0.00582776 0.0033157 0.00852428
Loa Loa (eye worm) hypothetical protein 0.00665372 0.00411076 0.0280294
Loa Loa (eye worm) hypothetical protein 0.00326517 0.000848973 0.00328961
Onchocerca volvulus 0.00419834 0.00174723 0.00101003
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.00326517 0.000848973 0.00249206
Echinococcus multilocularis voltage gated potassium channel 0.00461835 0.00215153 0.00631556
Mycobacterium ulcerans short chain dehydrogenase 0.00326517 0.000848973 0.000219363
Leishmania major pteridine reductase 1 0.00326517 0.000848973 0.0297801
Brugia malayi Src substrate cortactin 0.00648856 0.00395177 0.0103937
Echinococcus granulosus cyclins 0.0046965 0.00222675 0.00653636
Schistosoma mansoni histone deacetylase 4 5 0.00582776 0.0033157 0.00973283
Schistosoma mansoni dynamin-associated protein 0.00648856 0.00395177 0.0115999
Schistosoma mansoni steroid dehydrogenase 0.00326517 0.000848973 0.00249206
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.00665372 0.00411076 0.00337531
Schistosoma mansoni short chain dehydrogenase 0.00326517 0.000848973 0.00249206
Echinococcus granulosus hematopoietic lineage cell specific protein 0.00648856 0.00395177 0.0115999
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.00326517 0.000848973 0.00249206
Schistosoma mansoni steroid dehydrogenase 0.00326517 0.000848973 0.00249206
Brugia malayi hexokinase type II 0.00293795 0.00053399 0.000348951
Trichomonas vaginalis short-chain dehydrogenase, putative 0.00326517 0.000848973 0.00229691
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0160354 0.0131415 0.0383872
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.00461835 0.00215153 0.00631556
Echinococcus granulosus shaker cognate 0.00461835 0.00215153 0.00631556
Echinococcus multilocularis lysosomal alpha glucosidase 0.135367 0.128009 0.375755
Toxoplasma gondii kringle domain-containing protein 0.0106696 0.00797645 0.299641
Echinococcus granulosus cyclin dependent kinase 0.0151369 0.0122766 0.0360365
Echinococcus granulosus potassium voltage gated channel subfamily H 0.00461835 0.00215153 0.00631556
Loa Loa (eye worm) hypothetical protein 0.00314983 0.000737941 0.00244747
Loa Loa (eye worm) hypothetical protein 0.00461835 0.00215153 0.0131692
Onchocerca volvulus 0.00648856 0.00395177 0.0032162
Trichomonas vaginalis alpha-glucosidase, putative 0.0111875 0.00847494 0.0246864
Echinococcus granulosus hexokinase 0.00936069 0.00671645 0.0197154
Entamoeba histolytica BAR/SH3 domain containing protein 0.00648856 0.00395177 0.112597
Leishmania major hypothetical protein, conserved 0.0106696 0.00797645 0.279796
Loa Loa (eye worm) hypothetical protein 0.00665372 0.00411076 0.0280294
Onchocerca volvulus 0.00877084 0.00614868 0.00541473
Echinococcus granulosus carbonic anhydrase 0.0170056 0.0140754 0.0413166
Loa Loa (eye worm) protein-tyrosine phosphatase 0.00665372 0.00411076 0.0280294
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0519862 0.0477473 0.140157
Brugia malayi Immunoglobulin I-set domain containing protein 0.010313 0.00763312 0.021213
Echinococcus multilocularis potassium voltage gated channel protein 0.00461835 0.00215153 0.00631556
Trichomonas vaginalis cyclin B, putative 0.00918563 0.00654795 0.0190288
Brugia malayi Guanylate kinase family protein 0.00648856 0.00395177 0.0103937
Schistosoma mansoni egf-like domain protein 0.00415942 0.00170977 0.00501882
Schistosoma mansoni transient receptor potential channel 0.00462401 0.00215698 0.00633154
Brugia malayi Variant SH3 domain containing protein 0.0131423 0.0103566 0.0292172
Trichomonas vaginalis cyclins, putative 0.00918563 0.00654795 0.0190288
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0182414 0.015265 0.0448085
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.030269 0.0268426 0.0776689
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.00326517 0.000848973 0.00249206
Entamoeba histolytica protein kinase, putative 0.0388439 0.0350967 1
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.00453453 0.00207084 0.0125571
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0454976 0.0415015 0.121823
Brugia malayi Plexin repeat family protein 0.00400784 0.00156385 0.00337569
Leishmania major quinonoid dihydropteridine reductase 0.00326517 0.000848973 0.0297801
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0519862 0.0477473 0.140157
Entamoeba histolytica protein kinase, putative 0.0069198 0.00436689 0.124424
Schistosoma mansoni carbonyl reductase 0.00326517 0.000848973 0.00249206
Schistosoma mansoni voltage-gated potassium channel 0.00461835 0.00215153 0.00631556
Brugia malayi Peripheral plasma membrane protein CASK 0.00648856 0.00395177 0.0103937
Echinococcus multilocularis histone deacetylase 0.00582776 0.0033157 0.00973283
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.030269 0.0268426 0.0787932
Loa Loa (eye worm) hypothetical protein 0.00461835 0.00215153 0.0131692
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0143229 0.011493 0.403151
Echinococcus multilocularis transient receptor potential cation channel 0.00462401 0.00215698 0.00633154
Echinococcus granulosus carbonyl reductase 1 0.00326517 0.000848973 0.00249206
Schistosoma mansoni cercarial elastase (S01 family) 0.00314983 0.000737941 0.00216614
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.00326517 0.000848973 0.00127467
Brugia malayi hypothetical protein 0.00665372 0.00411076 0.0108609
Loa Loa (eye worm) oxidoreductase 0.00326517 0.000848973 0.00328961
Loa Loa (eye worm) hypothetical protein 0.00461835 0.00215153 0.0131692
Trypanosoma cruzi paraflagellar rod protein 5, putative 0.00648856 0.00395177 0.138619
Schistosoma mansoni formin binding protein and related proteins 0.00648856 0.00395177 0.0115999
Trichomonas vaginalis alpha-glucosidase, putative 0.0300377 0.02662 0.0779594
Echinococcus multilocularis tissue type plasminogen activator 0.0106696 0.00797645 0.0234139
Echinococcus multilocularis ryanodine receptor 44f 0.00461835 0.00215153 0.00631556
Loa Loa (eye worm) TK/FER protein kinase 0.00877084 0.00614868 0.0434864
Leishmania major developmentally regulated phosphoprotein-like protein 0.0319992 0.0285081 1
Schistosoma mansoni cercarial elastase (S01 family) 0.00314983 0.000737941 0.00216614
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.030269 0.0268426 0.941579
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.00326517 0.000848973 0.0318924
Trichomonas vaginalis cyclins, putative 0.00568925 0.00318237 0.00914765
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0111875 0.00847494 0.0246864
Schistosoma mansoni voltage-gated ion channel 0.00461835 0.00215153 0.00631556
Onchocerca volvulus 0.00877084 0.00614868 0.00541473
Mycobacterium ulcerans epoxide hydrolase EphA 0.0194801 0.0164573 0.0310564
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.00326517 0.000848973 0.0297801
Schistosoma mansoni voltage-dependent calcium channel 0.00461835 0.00215153 0.00631556
Echinococcus multilocularis conserved hypothetical protein 0.00461835 0.00215153 0.00631556
Loa Loa (eye worm) carbonic anhydrase 3 0.030269 0.0268426 0.200444
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0160354 0.0131415 0.493671
Echinococcus multilocularis endophilin A3 0.00648856 0.00395177 0.0115999
Echinococcus multilocularis carbonyl reductase 1 0.00326517 0.000848973 0.00249206
Loa Loa (eye worm) hypothetical protein 0.00326517 0.000848973 0.00328961
Trichomonas vaginalis cyclin B3, putative 0.0046965 0.00222675 0.006342
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.00461835 0.00215153 0.00510284
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.00461835 0.00215153 0.00141463
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0111875 0.00847494 0.297282
Echinococcus granulosus potassium voltage gated channel protein 0.00461835 0.00215153 0.00631556
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.00461835 0.00215153 0.00631556
Schistosoma mansoni tyrosine kinase 0.0152594 0.0123945 0.0363826
Schistosoma mansoni tyrosine kinase 0.00877084 0.00614868 0.0180487
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.00326517 0.000848973 0.0603162
Leishmania major hypothetical protein, conserved 0.00461835 0.00215153 0.0754709
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0151369 0.0122766 0.430636
Echinococcus multilocularis conserved hypothetical protein 0.00326517 0.000848973 0.00249206
Schistosoma mansoni short chain dehydrogenase 0.00326517 0.000848973 0.00249206
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0300377 0.02662 0.758474
Echinococcus multilocularis growth factor receptor bound protein 2 0.0131423 0.0103566 0.0304005
Toxoplasma gondii histone deacetylase HDAC1 0.00582776 0.0033157 0.124557
Echinococcus multilocularis cyclin B 0.00918563 0.00654795 0.0192207
Leishmania major quinonoid dihydropteridine reductase 0.00326517 0.000848973 0.0297801
Echinococcus granulosus voltage gated potassium channel 0.00461835 0.00215153 0.00631556
Plasmodium falciparum protein kinase 5 0.0151369 0.0122766 0.872205
Mycobacterium tuberculosis Conserved protein 0.356294 0.340671 0.671526
Loa Loa (eye worm) hypothetical protein 0.00665372 0.00411076 0.0280294
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.00461835 0.00215153 0.00631556
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0160354 0.0131415 0.0385753
Trichomonas vaginalis conserved hypothetical protein 0.00648856 0.00395177 0.0114066
Schistosoma mansoni carbonic anhydrase 0.0170056 0.0140754 0.0413166
Loa Loa (eye worm) hypothetical protein 0.00648856 0.00395177 0.0268235
Echinococcus multilocularis caspase 2 0.0988609 0.0928685 0.272604
Mycobacterium ulcerans short chain dehydrogenase 0.00326517 0.000848973 0.000219363
Brugia malayi Dehydrogenases, short chain protein 2 0.00326517 0.000848973 0.00127467
Trypanosoma cruzi cdc2-related kinase 1 0.0151369 0.0122766 0.430636
Leishmania major hypothetical protein, conserved 0.00326517 0.000848973 0.0297801
Echinococcus multilocularis transmembrane protease serine 3 0.00314983 0.000737941 0.00216614
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0151369 0.0122766 0.46118
Entamoeba histolytica cyclin, putative 0.0046965 0.00222675 0.0634461
Brugia malayi Retinol dehydrogenase 12 0.00326517 0.000848973 0.00127467
Trypanosoma cruzi cyclin, putative 0.00918563 0.00654795 0.229687
Loa Loa (eye worm) histone deacetylase 0.00582776 0.0033157 0.021999
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.00461835 0.00215153 0.00631556
Loa Loa (eye worm) hypothetical protein 0.00461835 0.00215153 0.0131692
Echinococcus multilocularis tyrosine protein kinase ABL1 0.139782 0.132259 0.388231
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.00326517 0.000848973 0.00249206
Leishmania major short chain dehydrogenase, putative 0.00326517 0.000848973 0.0297801
Schistosoma mansoni serine/threonine protein kinase 0.0151369 0.0122766 0.0360365
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.00918563 0.00654795 0.229687
Onchocerca volvulus 0.00877084 0.00614868 0.00541473
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.00326517 0.000848973 0.0297801
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0319992 0.0285081 0.083682
Mycobacterium ulcerans short chain dehydrogenase 0.00326517 0.000848973 0.000219363
Loa Loa (eye worm) bone morphogenetic protein 1b 0.00456133 0.00209664 0.0127528
Schistosoma mansoni hypothetical protein 0.0106696 0.00797645 0.0234139
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.00461835 0.00215153 0.00510284
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0454976 0.0415015 0.121823
Mycobacterium ulcerans short chain dehydrogenase 0.00326517 0.000848973 0.000219363
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0143229 0.011493 0.403151
Schistosoma mansoni plexin 0.00400784 0.00156385 0.00459051
Echinococcus multilocularis voltage dependent calcium channel 0.00461835 0.00215153 0.00631556
Echinococcus granulosus plexin a4 0.00477216 0.00229959 0.00675016
Echinococcus granulosus hypothetical protein 0.00326517 0.000848973 0.00249206
Echinococcus granulosus sodium leak channel non selective protein 0.00461835 0.00215153 0.00631556
Brugia malayi Protein kinase domain containing protein 0.00877084 0.00614868 0.0168503
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.00665372 0.00411076 0.0120666
Brugia malayi SH2 domain containing protein 0.00877084 0.00614868 0.0168503
Loa Loa (eye worm) hypothetical protein 0.00461835 0.00215153 0.0131692
Schistosoma mansoni carbonic anhydrase-related 0.0170056 0.0140754 0.0413166
Echinococcus granulosus neutral alpha glucosidase AB 0.0300377 0.02662 0.0781397
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.00461835 0.00215153 0.00631556
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0170056 0.0140754 0.0401465
Onchocerca volvulus 0.00665372 0.00411076 0.00337531
Schistosoma mansoni carbonyl reductase 0.00326517 0.000848973 0.00249206
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.00326517 0.000848973 0.00249206
Schistosoma mansoni short chain dehydrogenase 0.00326517 0.000848973 0.00249206
Trichomonas vaginalis CMGC family protein kinase 0.0151369 0.0122766 0.0358479
Brugia malayi Kringle domain containing protein 0.0106696 0.00797645 0.022222
Leishmania major 3-keto-dihydrosphingosine reductase 0.00326517 0.000848973 0.0297801
Loa Loa (eye worm) TK/FER protein kinase 0.00877084 0.00614868 0.0434864
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.00461835 0.00215153 0.00631556
Mycobacterium ulcerans oxidoreductase 0.00326517 0.000848973 0.000219363
Echinococcus granulosus carbonic anhydrase 0.0170056 0.0140754 0.0413166
Schistosoma mansoni short chain dehydrogenase 0.00326517 0.000848973 0.00249206
Schistosoma mansoni inositol 145-trisphosphate receptor 0.00461835 0.00215153 0.00631556
Echinococcus granulosus voltage gated potassium channel 0.00461835 0.00215153 0.00631556
Trypanosoma cruzi hypothetical protein, conserved 0.00326517 0.000848973 0.0297801
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0143229 0.011493 0.403151
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.00461835 0.00215153 0.0754709
Echinococcus multilocularis steroid dehydrogenase 0.00326517 0.000848973 0.00249206
Mycobacterium ulcerans short chain dehydrogenase 0.00326517 0.000848973 0.000219363
Mycobacterium ulcerans short chain dehydrogenase 0.00326517 0.000848973 0.000219363
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.00665372 0.00411076 0.0120666
Brugia malayi Cyclin, N-terminal domain containing protein 0.0139923 0.0111748 0.031622
Trichomonas vaginalis steroid dehydrogenase, putative 0.00326517 0.000848973 0.00229691
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.00499658 0.00251561 0.00738427
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.00461835 0.00215153 0.00510284
Onchocerca volvulus 0.00648856 0.00395177 0.0032162
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.00326517 0.000848973 0.00127467
Mycobacterium ulcerans ketoacyl reductase 0.00326517 0.000848973 0.000219363
Schistosoma mansoni steroid dehydrogenase 0.00326517 0.000848973 0.00249206
Trichomonas vaginalis conserved hypothetical protein 0.0160354 0.0131415 0.0383872
Echinococcus granulosus expressed protein 0.00648856 0.00395177 0.0115999
Echinococcus multilocularis transient receptor potential gamma protein 0.00461835 0.00215153 0.00631556
Schistosoma mansoni voltage-gated potassium channel 0.00461835 0.00215153 0.00631556
Loa Loa (eye worm) prolyl oligopeptidase 0.0230557 0.0198992 0.14778
Echinococcus granulosus breast cancer anti estrogen resistance protein 0.00648856 0.00395177 0.0115999
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.00461835 0.00215153 0.00631556
Plasmodium vivax histone deacetylase, putative 0.00582776 0.0033157 0.200669
Echinococcus multilocularis hematopoietic lineage cell specific protein 0.00648856 0.00395177 0.0115999
Echinococcus granulosus tyrosine kinase 0.00877084 0.00614868 0.0180487
Echinococcus granulosus endophilin A3 0.00648856 0.00395177 0.0115999
Mycobacterium tuberculosis Hypothetical protein 0.356294 0.340671 0.671526
Trichomonas vaginalis cyclins, putative 0.00918563 0.00654795 0.0190288
Brugia malayi Tyrosine-protein kinase abl-1 0.0653521 0.0606132 0.17692
Brugia malayi Protein kinase domain containing protein 0.0151369 0.0122766 0.03486
Echinococcus granulosus carbonic anhydrase 0.0170056 0.0140754 0.0413166
Mycobacterium ulcerans short chain dehydrogenase 0.528977 0.506894 1
Schistosoma mansoni cercarial elastase (S01 family) 0.00314983 0.000737941 0.00216614
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0182414 0.015265 0.0448085
Trichomonas vaginalis short-chain dehydrogenase, putative 0.00326517 0.000848973 0.00229691
Trypanosoma cruzi cdc2-related kinase 3 0.0151369 0.0122766 0.430636
Echinococcus granulosus SHC transforming protein 3 0.00665372 0.00411076 0.0120666
Echinococcus granulosus cyclins 0.0046965 0.00222675 0.00653636
Echinococcus granulosus cyclins 0.0046965 0.00222675 0.00653636
Onchocerca volvulus 0.00752331 0.00494782 0.00421298
Trypanosoma brucei conserved protein 0.00648856 0.00395177 0.138619
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0139923 0.0111748 0.0328024
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.00665372 0.00411076 0.0120666
Loa Loa (eye worm) hypothetical protein 0.00665372 0.00411076 0.0280294
Leishmania major hypothetical protein, unknown function 0.00461835 0.00215153 0.0754709
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.00461835 0.00215153 0.00631556
Echinococcus granulosus potassium voltage gated channel subfamily D 0.00461835 0.00215153 0.00631556
Loa Loa (eye worm) TK/FER protein kinase 0.00877084 0.00614868 0.0434864
Echinococcus granulosus tyrosine protein kinase HCK 0.0388439 0.0350967 0.103022
Schistosoma mansoni pyruvate dehydrogenase 0.0319992 0.0285081 0.083682
Loa Loa (eye worm) hypothetical protein 0.00461835 0.00215153 0.0131692
Loa Loa (eye worm) TK protein kinase 0.0388439 0.0350967 0.263049
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.00326517 0.000848973 0.00127467
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.00326517 0.000848973 0.00127467
Echinococcus granulosus nostrin 0.00648856 0.00395177 0.0115999
Trichomonas vaginalis conserved hypothetical protein 0.0160354 0.0131415 0.0383872
Giardia lamblia Hypothetical protein 0.0046965 0.00222675 0.00405441
Schistosoma mansoni steroid dehydrogenase 0.00326517 0.000848973 0.00249206
Loa Loa (eye worm) oxidoreductase 0.00326517 0.000848973 0.00328961
Onchocerca volvulus 0.00326517 0.000848973 0.000111114
Brugia malayi voltage-dependent calcium channel 0.00461835 0.00215153 0.00510284
Trypanosoma brucei oxidoreductase-like protein 0.00326517 0.000848973 0.0297801
Loa Loa (eye worm) thyroid receptor interactor 0.00648856 0.00395177 0.0268235
Schistosoma mansoni growth factor receptor-bound protein 0.0131423 0.0103566 0.0304005
Echinococcus granulosus cyclic nucleotide gated cation channel 0.00461835 0.00215153 0.00631556
Trypanosoma brucei histone deacetylase 4 0.00582776 0.0033157 0.116307
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0319992 0.0285081 1
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.00326517 0.000848973 0.00249206
Trichomonas vaginalis CMGC family protein kinase 0.0151369 0.0122766 0.0358479
Brugia malayi cytokine inducible SH2-containing protein 5 0.00665372 0.00411076 0.0108609
Echinococcus granulosus SH2 domain containing adapter protein F 0.00665372 0.00411076 0.0120666
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0194801 0.0164573 0.0308438
Entamoeba histolytica SH2-protein kinase domain containing protein 0.00877084 0.00614868 0.175192
Echinococcus multilocularis neutral alpha glucosidase AB 0.0300377 0.02662 0.0781397
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0111875 0.00847494 0.0246864
Onchocerca volvulus 0.00877084 0.00614868 0.00541473
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0300377 0.02662 1
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.00461835 0.00215153 0.00631556
Echinococcus granulosus Mastin 0.00314983 0.000737941 0.00216614
Brugia malayi Spectrin alpha chain 0.00648856 0.00395177 0.0103937
Schistosoma mansoni caspase-7 (C14 family) 0.0700197 0.0651063 0.191112
Schistosoma mansoni hypothetical protein 0.00665372 0.00411076 0.0120666
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.00461835 0.00215153 0.00631556
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.00326517 0.000848973 0.000111114
Loa Loa (eye worm) hypothetical protein 0.00326517 0.000848973 0.00328961
Schistosoma mansoni voltage-gated potassium channel 0.00461835 0.00215153 0.00631556
Schistosoma mansoni pyruvate dehydrogenase 0.0302779 0.0268512 0.0788184
Brugia malayi Hexokinase family protein 0.00575255 0.0032433 0.00831151
Echinococcus granulosus histone deacetylase 7 0.00582776 0.0033157 0.00973283
Loa Loa (eye worm) hypothetical protein 0.00461835 0.00215153 0.0131692
Plasmodium falciparum histone deacetylase, putative 0.00582776 0.0033157 0.235567
Mycobacterium ulcerans hypothetical protein 0.356294 0.340671 0.671598
Echinococcus granulosus tyrosine protein kinase Src42A 0.0519862 0.0477473 0.140157
Brugia malayi hypothetical protein 0.00776969 0.00518498 0.014018
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0160354 0.0131415 0.0383872
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.00665372 0.00411076 0.0120666
Echinococcus multilocularis 0.00665372 0.00411076 0.0120666
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0069198 0.00436689 0.124424
Loa Loa (eye worm) hypothetical protein 0.00419834 0.00174723 0.0101026
Loa Loa (eye worm) hypothetical protein 0.00326517 0.000848973 0.00328961
Schistosoma mansoni Dab2-interacting protein-like 0.00648856 0.00395177 0.0115999
Onchocerca volvulus 0.00877084 0.00614868 0.00541473
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0700197 0.0651063 0.191112
Trichomonas vaginalis alpha-glucosidase, putative 0.0300377 0.02662 0.0779594
Schistosoma mansoni sorting nexin 0.00648856 0.00395177 0.0115999
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.00461835 0.00215153 0.00631556
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0111875 0.00847494 0.297282
Schistosoma mansoni short chain dehydrogenase 0.00326517 0.000848973 0.00249206
Brugia malayi hypothetical protein 0.00461835 0.00215153 0.00510284
Loa Loa (eye worm) hypothetical protein 0.00326517 0.000848973 0.00328961
Plasmodium falciparum histone deacetylase 2 0.00582776 0.0033157 0.235567
Brugia malayi Thioredoxin family protein 0.356294 0.340671 1
Loa Loa (eye worm) variant SH3 domain-containing protein 0.00648856 0.00395177 0.0268235
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.00326517 0.000848973 0.00249206
Loa Loa (eye worm) hypothetical protein 0.00293795 0.00053399 0.000900555
Toxoplasma gondii transporter, cation channel family protein 0.00461835 0.00215153 0.080824
Echinococcus multilocularis fibrillin 1 0.00415942 0.00170977 0.00501882
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.00314983 0.000737941 0.00216614
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.00461835 0.00215153 0.0754709
Brugia malayi Variant SH3 domain containing protein 0.00648856 0.00395177 0.0103937
Trypanosoma brucei glucosidase, putative 0.0300377 0.02662 0.933769
Schistosoma mansoni hypothetical protein 0.0170056 0.0140754 0.0413166
Loa Loa (eye worm) hypothetical protein 0.00461835 0.00215153 0.0131692
Onchocerca volvulus 0.00665372 0.00411076 0.00337531
Loa Loa (eye worm) hypothetical protein 0.00642273 0.00388841 0.0263429
Trichomonas vaginalis cyclin D, putative 0.0046965 0.00222675 0.006342
Schistosoma mansoni voltage-gated potassium channel 0.00461835 0.00215153 0.00631556
Loa Loa (eye worm) hypothetical protein 0.00648856 0.00395177 0.0268235
Schistosoma mansoni tyrosine kinase 0.133129 0.125854 0.36943
Echinococcus multilocularis cyclin dependent kinase 0.0151369 0.0122766 0.0360365
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.00326517 0.000848973 0.0297801
Schistosoma mansoni tyrosine kinase 0.0087765 0.00615412 0.0180647
Brugia malayi Protein kinase domain containing protein 0.00877084 0.00614868 0.0168503
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.00326517 0.000848973 0.00229691
Schistosoma mansoni carbonic anhydrase-related 0.0170056 0.0140754 0.0413166
Loa Loa (eye worm) SH2 domain-containing protein 0.00665372 0.00411076 0.0280294
Treponema pallidum hexokinase (hxk) 0.00936069 0.00671645 0.5
Giardia lamblia G2/mitotic-specific cyclin B 0.00918563 0.00654795 0.0167705
Brugia malayi Calcium binding EGF domain containing protein 0.00415942 0.00170977 0.00380452
Echinococcus multilocularis two pore calcium channel protein 1 0.00461835 0.00215153 0.00631556
Trypanosoma cruzi hypothetical protein, conserved 0.00326517 0.000848973 0.0297801
Loa Loa (eye worm) plexin A 0.00477216 0.00229959 0.0142921
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.00461835 0.00215153 0.00631556
Schistosoma mansoni retinoic acid receptor RXR 0.00519243 0.00270413 0.00793767
Brugia malayi Protein kinase domain containing protein 0.00877084 0.00614868 0.0168503
Plasmodium falciparum metacaspase 1 0.0160354 0.0131415 0.933652
Schistosoma mansoni voltage-gated potassium channel 0.00461835 0.00215153 0.00631556
Schistosoma mansoni steroid dehydrogenase 0.00326517 0.000848973 0.00249206
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.00326517 0.000848973 0.0297801
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.00461835 0.00215153 0.00631556
Brugia malayi ion channel NompC 0.00461835 0.00215153 0.00510284
Onchocerca volvulus 0.00648856 0.00395177 0.0032162
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.00461835 0.00215153 0.00510284
Loa Loa (eye worm) hypothetical protein 0.00655322 0.00401402 0.0272956
Schistosoma mansoni short-chain dehydrogenase/reductase 0.00326517 0.000848973 0.00249206
Echinococcus multilocularis potassium large conductance calcium activated 0.00461835 0.00215153 0.00631556
Echinococcus granulosus N chimaerin 0.00665372 0.00411076 0.0120666
Loa Loa (eye worm) oxidoreductase 0.00326517 0.000848973 0.00328961
Echinococcus granulosus expressed conserved protein 0.00665372 0.00411076 0.0120666
Onchocerca volvulus 0.00326517 0.000848973 0.000111114
Echinococcus granulosus SH2 domain containing protein 7 0.00665372 0.00411076 0.0120666
Loa Loa (eye worm) hypothetical protein 0.00665372 0.00411076 0.0280294
Schistosoma mansoni vesicular amine transporter 0.00512554 0.00263975 0.00774866
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.00314983 0.000737941 0.00216614
Onchocerca volvulus 0.00936069 0.00671645 0.00598293
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.00453453 0.00207084 0.00486569
Brugia malayi Trypsin family protein 0.00314983 0.000737941 0.000948355
Echinococcus granulosus tyrosine protein kinase ABL1 0.139782 0.132259 0.388231
Giardia lamblia Hypothetical protein 0.356294 0.340671 1
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.00326517 0.000848973 0.0241895
Echinococcus multilocularis TRP (transient receptor potential) channel 0.00461835 0.00215153 0.00631556
Echinococcus granulosus potassium voltage gated channel protein 0.00461835 0.00215153 0.00631556
Echinococcus multilocularis fch and double sh3 domains protein 2 0.00648856 0.00395177 0.0115999
Echinococcus granulosus cyclins 0.0046965 0.00222675 0.00653636
Schistosoma mansoni dreadlocks/dock 0.00648856 0.00395177 0.0115999
Plasmodium falciparum carbonic anhydrase 0.0170056 0.0140754 1
Schistosoma mansoni alpha-glucosidase 0.116517 0.109864 0.322493
Echinococcus multilocularis suppressor of cytokine signaling 7 0.00665372 0.00411076 0.0120666
Mycobacterium ulcerans short chain dehydrogenase 0.00326517 0.000848973 0.000219363
Loa Loa (eye worm) hypothetical protein 0.00648856 0.00395177 0.0268235
Echinococcus multilocularis carbonic anhydrase 0.0170056 0.0140754 0.0413166
Brugia malayi Variant SH3 domain containing protein 0.00648856 0.00395177 0.0103937
Trypanosoma brucei pyruvate dehydrogenase (lipoamide) kinase, putative 0.0118734 0.00913514 0.320441
Schistosoma mansoni short chain dehydrogenase 0.00326517 0.000848973 0.00249206
Entamoeba histolytica hypothetical protein 0.00648856 0.00395177 0.112597
Echinococcus multilocularis hexokinase type 2 0.00936069 0.00671645 0.0197154
Echinococcus granulosus tyrosine protein kinase Fps85D 0.00877084 0.00614868 0.0180487
Loa Loa (eye worm) hypothetical protein 0.00493643 0.00245771 0.0154914
Schistosoma mansoni suppressor of cytokine signaling 0.00665372 0.00411076 0.0120666
Onchocerca volvulus LIM and SH3 domain protein homolog 0.00648856 0.00395177 0.0032162
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0230557 0.0198992 0.0584116
Brugia malayi SH2 domain containing protein 0.00665372 0.00411076 0.0108609
Brugia malayi Variant SH3 domain containing protein 0.00648856 0.00395177 0.0103937
Trichomonas vaginalis cyclin A, putative 0.00918563 0.00654795 0.0190288
Plasmodium vivax hypothetical protein, conserved 0.0160354 0.0131415 1
Trypanosoma cruzi short-chain dehydrogenase, putative 0.00326517 0.000848973 0.0297801
Brugia malayi oxidoreductase 0.00326517 0.000848973 0.00127467
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.00665372 0.00411076 0.0120666
Trypanosoma brucei short-chain dehydrogenase, putative 0.00326517 0.000848973 0.0297801
Loa Loa (eye worm) hypothetical protein 0.0170056 0.0140754 0.103608
Trypanosoma brucei carbonic anhydrase-like protein 0.030269 0.0268426 0.941579
Mycobacterium ulcerans ketoacyl reductase 0.00326517 0.000848973 0.000219363
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.00326517 0.000848973 0.0297801
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.00326517 0.000848973 0.0297801
Echinococcus granulosus histone deacetylase 6 0.00582776 0.0033157 0.00973283
Schistosoma mansoni tyrosine kinase 0.002412 0.0000277123 0.0000813462
Onchocerca volvulus 0.00326517 0.000848973 0.000111114
Toxoplasma gondii hexokinase 0.00936069 0.00671645 0.252309
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0230557 0.0198992 0.0584116
Trichomonas vaginalis short-chain dehydrogenase, putative 0.00326517 0.000848973 0.00229691
Schistosoma mansoni steroid dehydrogenase 0.00326517 0.000848973 0.00249206
Brugia malayi Sex muscle abnormal protein 5 0.0131423 0.0103566 0.0292172
Brugia malayi Hexokinase family protein 0.00936069 0.00671645 0.018519
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0519862 0.0477473 0.140157
Brugia malayi Trypsin family protein 0.00314983 0.000737941 0.000948355
Toxoplasma gondii transporter, cation channel family protein 0.00461835 0.00215153 0.080824
Loa Loa (eye worm) TK/ABL protein kinase 0.139782 0.132259 1
Loa Loa (eye worm) SH2 domain-containing protein 0.00665372 0.00411076 0.0280294
Echinococcus granulosus sodium channel protein 0.00461835 0.00215153 0.00631556
Schistosoma mansoni GTPase activating protein 0.00665372 0.00411076 0.0120666
Echinococcus granulosus transient receptor potential cation channel 0.00461835 0.00215153 0.00631556
Trichomonas vaginalis conserved hypothetical protein 0.00648856 0.00395177 0.0114066
Echinococcus multilocularis tyrosine protein kinase HCK 0.0388439 0.0350967 0.103022
Trichomonas vaginalis conserved hypothetical protein 0.0160354 0.0131415 0.0383872
Brugia malayi Variant SH3 domain containing protein 0.00648856 0.00395177 0.0103937
Echinococcus multilocularis slit robo rho gtpase activating protein 1 0.00648856 0.00395177 0.0115999
Echinococcus granulosus potassium voltage gated channel protein 0.00461835 0.00215153 0.00631556
Brugia malayi hypothetical protein 0.00877084 0.00614868 0.0168503
Schistosoma mansoni 60S ribosomal protein L21 0.00461835 0.00215153 0.00631556
Brugia malayi plexin A 0.00477216 0.00229959 0.00553797
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.00461835 0.00215153 0.00631556
Trypanosoma cruzi hexokinase, putative 0.00936069 0.00671645 0.235598
Loa Loa (eye worm) variant SH3 domain-containing protein 0.00665372 0.00411076 0.0280294
Trypanosoma brucei developmentally regulated phosphoprotein 0.0319992 0.0285081 1
Onchocerca volvulus 0.00326517 0.000848973 0.000111114
Loa Loa (eye worm) oxidoreductase 0.00326517 0.000848973 0.00328961
Brugia malayi Fes/CIP4 homology domain containing protein 0.00648856 0.00395177 0.0103937
Schistosoma mansoni carbonyl reductase 0.00326517 0.000848973 0.00249206
Leishmania major alpha glucosidase II subunit, putative 0.0300377 0.02662 0.933769
Echinococcus granulosus fch and double sh3 domains protein 2 0.00648856 0.00395177 0.0115999
Entamoeba histolytica hypothetical protein 0.00648856 0.00395177 0.112597
Schistosoma mansoni voltage-gated potassium channel 0.00461835 0.00215153 0.00631556
Mycobacterium ulcerans short chain dehydrogenase 0.00326517 0.000848973 0.000219363
Entamoeba histolytica hypothetical protein 0.00326517 0.000848973 0.0241895
Trypanosoma cruzi histone deacetylase, putative 0.00582776 0.0033157 0.116307
Mycobacterium tuberculosis Conserved hypothetical protein 0.356294 0.340671 0.671526
Echinococcus granulosus growth factor receptor bound protein 2 0.0131423 0.0103566 0.0304005
Trypanosoma brucei metacaspase MCA3 0.0160354 0.0131415 0.460975
Loa Loa (eye worm) voltage-dependent calcium channel 0.00461835 0.00215153 0.0131692
Brugia malayi SH2 domain containing protein 0.00877084 0.00614868 0.0168503
Echinococcus granulosus enteropeptidase 0.00314983 0.000737941 0.00216614
Schistosoma mansoni voltage-gated potassium channel 0.00461835 0.00215153 0.00631556
Mycobacterium ulcerans short-chain dehydrogenase 0.00326517 0.000848973 0.000219363
Mycobacterium ulcerans ketoacyl reductase 0.00326517 0.000848973 0.000219363
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.00326517 0.000848973 0.0297801
Trichomonas vaginalis conserved hypothetical protein 0.00648856 0.00395177 0.0114066
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.00461835 0.00215153 0.00510284
Leishmania major metacaspase, putative 0.0160354 0.0131415 0.460975
Plasmodium vivax protein kinase Crk2 0.0151369 0.0122766 0.929641
Mycobacterium ulcerans short-chain dehydrogenase 0.00326517 0.000848973 0.000219363
Echinococcus granulosus hexokinase 0.00936069 0.00671645 0.0197154
Loa Loa (eye worm) hypothetical protein 0.00665372 0.00411076 0.0280294
Echinococcus granulosus voltage dependent calcium channel 0.00461835 0.00215153 0.00631556
Echinococcus multilocularis voltage gated potassium channel 0.00461835 0.00215153 0.00631556
Echinococcus granulosus laminin 0.00415942 0.00170977 0.00501882
Loa Loa (eye worm) TK/ROR protein kinase 0.0129163 0.010139 0.0737523
Echinococcus granulosus tyrosine kinase 0.0454976 0.0415015 0.121823
Echinococcus multilocularis short transient receptor potential channel 6 0.00462401 0.00215698 0.00633154
Echinococcus multilocularis histone deacetylase 6 0.00582776 0.0033157 0.00973283
Trypanosoma cruzi cdc2-related kinase 3 0.0151369 0.0122766 0.430636
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.00326517 0.000848973 0.00249206
Loa Loa (eye worm) hypothetical protein 0.00314983 0.000737941 0.00244747
Echinococcus granulosus potassium voltage gated channel subfamily C 0.00461835 0.00215153 0.00631556
Echinococcus granulosus histone deacetylase 6 0.00582776 0.0033157 0.00973283
Onchocerca volvulus 0.00326517 0.000848973 0.000111114
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.00461835 0.00215153 0.00631556
Loa Loa (eye worm) hypothetical protein 0.00665372 0.00411076 0.0280294
Echinococcus granulosus c src tyrosine kinase 0.0152594 0.0123945 0.0363826
Schistosoma mansoni hypothetical protein 0.068911 0.064039 0.187979
Echinococcus multilocularis carbonyl reductase 1 0.00326517 0.000848973 0.00249206
Loa Loa (eye worm) calcium channel 0.00461835 0.00215153 0.0131692
Echinococcus multilocularis tyrosine kinase 0.00877084 0.00614868 0.0180487
Echinococcus granulosus steroid dehydrogenase 0.00326517 0.000848973 0.00249206
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0151369 0.0122766 0.089965
Loa Loa (eye worm) p53BP2 0.00648856 0.00395177 0.0268235
Onchocerca volvulus 1.04125 1 1
Entamoeba histolytica BAR/SH3 domain containing protein 0.00648856 0.00395177 0.112597
Echinococcus granulosus SH2 motif 0.00665372 0.00411076 0.0120666
Trypanosoma cruzi metacaspase, putative 0.0160354 0.0131415 0.460975
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.00326517 0.000848973 0.00127467
Mycobacterium ulcerans short chain dehydrogenase 0.00361439 0.00118512 0.000883485
Schistosoma mansoni voltage-gated potassium channel 0.00461835 0.00215153 0.00631556
Mycobacterium ulcerans short chain dehydrogenase 0.00326517 0.000848973 0.000219363
Schistosoma mansoni tensin-related 0.00665372 0.00411076 0.0120666
Onchocerca volvulus 0.00877084 0.00614868 0.00541473
Echinococcus multilocularis hexokinase 0.00936069 0.00671645 0.0197154
Leishmania major short chain dehydrogenase/reductase, putative 0.00326517 0.000848973 0.0297801
Loa Loa (eye worm) hypothetical protein 0.00461835 0.00215153 0.0131692
Leishmania major short chain dehydrogenase, putative 0.00326517 0.000848973 0.0297801
Trichomonas vaginalis maltase-glucoamylase, putative 0.0300377 0.02662 0.0779594
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.00326517 0.000848973 0.000219363
Echinococcus granulosus histone deacetylase 0.00582776 0.0033157 0.00973283
Schistosoma mansoni hypothetical protein 0.00648856 0.00395177 0.0115999
Onchocerca volvulus 0.00461835 0.00215153 0.00141463
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0131423 0.0103566 0.0754022
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.00648856 0.00395177 0.0115999
Loa Loa (eye worm) dehydrogenase 0.00326517 0.000848973 0.00328961
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.00461835 0.00215153 0.00631556
Leishmania major short chain dehydrogenase/reductase, putative 0.00326517 0.000848973 0.0297801
Trypanosoma brucei cdc2-related kinase 1 0.0151369 0.0122766 0.430636
Entamoeba histolytica protein kinase domain containing protein 0.00288145 0.000479601 0.0136651
Echinococcus multilocularis signal transduction protein lnk realted 0.00665372 0.00411076 0.0120666
Loa Loa (eye worm) hypothetical protein 0.00314983 0.000737941 0.00244747
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0111875 0.00847494 0.241474
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.00461835 0.00215153 0.00631556
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.00326517 0.000848973 0.000219363
Schistosoma mansoni ryanodine receptor related 0.00461835 0.00215153 0.00631556
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.00461835 0.00215153 0.00631556
Echinococcus multilocularis histone deacetylase 7 0.00582776 0.0033157 0.00973283
Echinococcus granulosus ryanodine receptor 44f 0.00461835 0.00215153 0.00631556
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0152594 0.0123945 0.0363826
Trypanosoma brucei Metacaspase-4 0.0160354 0.0131415 0.460975
Echinococcus multilocularis SH2 motif 0.00665372 0.00411076 0.0120666
Schistosoma mansoni suppressor of cytokine signaling 0.00665372 0.00411076 0.0120666
Brugia malayi hypothetical protein 0.00326517 0.000848973 0.00127467
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.00326517 0.000848973 0.0297801
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.00326517 0.000848973 0.000219363
Toxoplasma gondii calcium binding egf domain-containing protein 0.00415942 0.00170977 0.0642288
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.00461835 0.00215153 0.00631556
Echinococcus granulosus potassium voltage gated channel protein 0.00461835 0.00215153 0.00631556
Schistosoma mansoni voltage-gated potassium channel 0.00461835 0.00215153 0.00631556
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.00461835 0.00215153 0.00510284
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.00326517 0.000848973 0.0297801
Echinococcus granulosus caspase 8 0.0160354 0.0131415 0.0385753
Leishmania major quinonoid dihydropteridine reductase 0.00326517 0.000848973 0.0297801
Loa Loa (eye worm) hypothetical protein 0.0170056 0.0140754 0.103608
Loa Loa (eye worm) hypothetical protein 0.0111875 0.00847494 0.0611305
Schistosoma mansoni transient receptor potential channel 4 0.00461835 0.00215153 0.00631556
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.00326517 0.000848973 0.0318924
Trypanosoma cruzi metacaspase, putative 0.0160354 0.0131415 0.460975
Loa Loa (eye worm) hypothetical protein 0.00665372 0.00411076 0.0280294
Schistosoma mansoni cercarial elastase (S01 family) 0.00314983 0.000737941 0.00216614
Trypanosoma cruzi cdc2-related kinase 1 0.0151369 0.0122766 0.430636
Brugia malayi SH2 domain containing protein 0.00665372 0.00411076 0.0108609
Toxoplasma gondii hypothetical protein 0.00461835 0.00215153 0.080824
Onchocerca volvulus Cell death protein 3 homolog 0.0988609 0.0928685 0.0921986
Onchocerca volvulus 0.00326517 0.000848973 0.000111114
Trypanosoma cruzi metacaspase, putative 0.0160354 0.0131415 0.460975
Loa Loa (eye worm) ryanodine receptor 0.00461835 0.00215153 0.0131692
Echinococcus granulosus transmembrane protease serine 3 0.00314983 0.000737941 0.00216614
Echinococcus multilocularis voltage gated hydrogen channel 1 0.00461835 0.00215153 0.00631556
Trypanosoma cruzi hypothetical protein, conserved 0.00326517 0.000848973 0.0297801
Mycobacterium ulcerans dehydrogenase 0.00326517 0.000848973 0.000219363
Echinococcus granulosus suppressor of cytokine signaling 7 0.00665372 0.00411076 0.0120666
Echinococcus granulosus Dipeptidyl peptidase 9 0.0143229 0.011493 0.0337365
Echinococcus multilocularis hexokinase 0.00936069 0.00671645 0.0197154
Leishmania major hypothetical protein, conserved 0.00648856 0.00395177 0.138619
Trichomonas vaginalis cyclin B, putative 0.00918563 0.00654795 0.0190288
Echinococcus multilocularis transfer RNA-Ala 0.00648856 0.00395177 0.0115999
Echinococcus granulosus SH2 motif 0.00665372 0.00411076 0.0120666
Entamoeba histolytica hypothetical protein 0.00648856 0.00395177 0.112597
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.00326517 0.000848973 0.000219363
Trypanosoma cruzi oxidoreductase-like protein, putative 0.00326517 0.000848973 0.0297801
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0151369 0.0122766 0.0360365
Trypanosoma cruzi hexokinase, putative 0.00936069 0.00671645 0.235598
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.00461835 0.00215153 0.00631556
Schistosoma mansoni caspase-7 (C14 family) 0.0988609 0.0928685 0.272604
Mycobacterium ulcerans hypothetical protein 0.356294 0.340671 0.671598
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.00326517 0.000848973 0.0297801
Loa Loa (eye worm) hypothetical protein 0.00461835 0.00215153 0.0131692
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0135947 0.010792 0.405412
Trichomonas vaginalis alpha-glucosidase, putative 0.0300377 0.02662 0.0779594
Echinococcus multilocularis transient receptor potential cation channel 0.00461835 0.00215153 0.00631556
Echinococcus granulosus apoptotic protease activating factor 1 0.068911 0.064039 0.187979
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.00326517 0.000848973 0.00127467
Trichomonas vaginalis alpha-glucosidase, putative 0.0111875 0.00847494 0.0246864
Onchocerca volvulus 0.00936069 0.00671645 0.00598293
Mycobacterium ulcerans short chain dehydrogenase 0.00326517 0.000848973 0.000219363
Schistosoma mansoni voltage-gated potassium channel 0.00461835 0.00215153 0.00631556
Mycobacterium ulcerans short chain dehydrogenase 0.00326517 0.000848973 0.000219363
Echinococcus multilocularis cyclins 0.0046965 0.00222675 0.00653636
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0230557 0.0198992 0.0191754
Brugia malayi Protein-tyrosine phosphatase containing protein 0.00665372 0.00411076 0.0108609
Mycobacterium ulcerans short-chain type oxidoreductase 0.00326517 0.000848973 0.000219363
Leishmania major hexokinase, putative 0.00936069 0.00671645 0.235598
Trichomonas vaginalis maltase-glucoamylase, putative 0.0111875 0.00847494 0.0246864
Echinococcus multilocularis Spectrin alpha actinin 0.00648856 0.00395177 0.0115999
Onchocerca volvulus 0.00648856 0.00395177 0.0032162
Loa Loa (eye worm) hypothetical protein 0.00461835 0.00215153 0.0131692
Schistosoma mansoni run and tbc1 domain containing 0.00648856 0.00395177 0.0115999
Brugia malayi SH2 domain containing protein 0.00665372 0.00411076 0.0108609
Echinococcus multilocularis cyclin dependent kinase 1 0.0151369 0.0122766 0.0360365
Leishmania major quinonoid dihydropteridine reductase 0.00326517 0.000848973 0.0297801
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.00461835 0.00215153 0.00631556
Schistosoma mansoni cercarial elastase (S01 family) 0.00314983 0.000737941 0.00216614
Echinococcus multilocularis N chimaerin 0.00665372 0.00411076 0.0120666
Brugia malayi Cell death protein 3 precursor 0.0988609 0.0928685 0.271717
Echinococcus granulosus tyrosine protein kinase Lyn 0.0522523 0.0480035 0.140908
Schistosoma mansoni apoptosis stimulating of P53 0.00648856 0.00395177 0.0115999
Echinococcus granulosus transient receptor potential cation channel 0.00461835 0.00215153 0.00631556
Loa Loa (eye worm) hypothetical protein 0.0319992 0.0285081 0.213076
Leishmania major calcium channel protein, putative,ion transporter, putative 0.00461835 0.00215153 0.0754709
Entamoeba histolytica tyrosin kinase, putative 0.00288145 0.000479601 0.0136651
Loa Loa (eye worm) TK/FER protein kinase 0.00877084 0.00614868 0.0434864
Loa Loa (eye worm) hypothetical protein 0.00462401 0.00215698 0.0132105
Loa Loa (eye worm) hypothetical protein 0.00461835 0.00215153 0.0131692
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0519862 0.0477473 0.140157
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.00461835 0.00215153 0.00631556
Leishmania major quinonoid dihydropteridine reductase 0.00326517 0.000848973 0.0297801
Mycobacterium ulcerans short chain dehydrogenase 0.00326517 0.000848973 0.000219363
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.00461835 0.00215153 0.0131692
Echinococcus multilocularis shaker cognate 0.00461835 0.00215153 0.00631556
Leishmania major dehydrogenase-like protein 0.00326517 0.000848973 0.0297801
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0160354 0.0131415 0.0374019
Brugia malayi Trypsin family protein 0.00314983 0.000737941 0.000948355
Onchocerca volvulus 0.00665372 0.00411076 0.00337531
Loa Loa (eye worm) hypothetical protein 0.00326517 0.000848973 0.00328961
Onchocerca volvulus Tyrosine kinase homolog 0.00976996 0.00711042 0.00637718
Brugia malayi Protein kinase domain containing protein 0.00877084 0.00614868 0.0168503
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.00392683 0.00148588 0.00436162
Echinococcus granulosus cyclic nucleotide gated cation channel 0.00461835 0.00215153 0.00631556
Loa Loa (eye worm) oxidoreductase 0.00326517 0.000848973 0.00328961
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.00326517 0.000848973 0.0318924
Schistosoma mansoni two-pore calcium channel 0.00461835 0.00215153 0.00631556
Echinococcus granulosus lysosomal alpha glucosidase 0.135367 0.128009 0.375755
Entamoeba histolytica hypothetical protein 0.00648856 0.00395177 0.112597
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.00326517 0.000848973 0.00127467
Brugia malayi Glycosyl hydrolases family 31 protein 0.0300377 0.02662 0.0770146
Entamoeba histolytica cyclin, putative 0.00918563 0.00654795 0.186569
Trypanosoma cruzi cyclin, putative 0.00918563 0.00654795 0.229687
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.030269 0.0268426 0.200444
Echinococcus multilocularis cyclin dependent kinase 5 0.0151369 0.0122766 0.0360365
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0170056 0.0140754 0.0401465
Loa Loa (eye worm) TK/FER protein kinase 0.00877084 0.00614868 0.0434864
Loa Loa (eye worm) hypothetical protein 0.00918563 0.00654795 0.0465148
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.00326517 0.000848973 0.00127467
Loa Loa (eye worm) hexokinase 0.00575255 0.0032433 0.0214499
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.00326517 0.000848973 0.000219363
Schistosoma mansoni slit-robo rho gtpase activating protein 0.00648856 0.00395177 0.0115999
Trichomonas vaginalis cyclins, putative 0.00918563 0.00654795 0.0190288
Entamoeba histolytica short chain dehydrogenase family protein 0.00326517 0.000848973 0.0241895
Entamoeba histolytica cyclin family protein 0.0046965 0.00222675 0.0634461
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.00461835 0.00215153 0.00631556
Echinococcus multilocularis enteropeptidase 0.00314983 0.000737941 0.00216614
Loa Loa (eye worm) hypothetical protein 0.00648856 0.00395177 0.0268235
Trypanosoma cruzi hypothetical protein, conserved 0.00326517 0.000848973 0.0297801
Trichomonas vaginalis alpha-glucosidase, putative 0.0300377 0.02662 0.0779594
Echinococcus multilocularis SH2 domain containing adapter protein F 0.00665372 0.00411076 0.0120666
Echinococcus granulosus tyrosine protein kinase Srms 0.00877084 0.00614868 0.0180487
Trichomonas vaginalis short-chain dehydrogenase, putative 0.00326517 0.000848973 0.00229691

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) = 0.262 uM Antiparasitic activity against Plasmodium falciparum assessed as parasite growth inhibition after 48 hrs by hydroethidine staining-based flow cytometric analysis ChEMBL. 24035097
Stabilty (ADMET) = 84 % Metabolic stability in mouse liver microsomes assessed as compound remaining at 1 uM preincubated for 5 mins followed by addition of NADPH generating solution measured after 30 mins by LC-MS/MS analysis ChEMBL. 24035097

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23 24035097

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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