Detailed information for compound 219773

Basic information

Technical information
  • TDR Targets ID: 219773
  • Name: (E)-6-[4-[2-(benzenesulfonamido)ethyl]phenyl] -6-pyridin-3-ylhex-5-enoic acid
  • MW: 450.55 | Formula: C25H26N2O4S
  • H donors: 2 H acceptors: 5 LogP: 4.42 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)CCC/C=C(/c1cccnc1)\c1ccc(cc1)CCNS(=O)(=O)c1ccccc1
  • InChi: 1S/C25H26N2O4S/c28-25(29)11-5-4-10-24(22-7-6-17-26-19-22)21-14-12-20(13-15-21)16-18-27-32(30,31)23-8-2-1-3-9-23/h1-3,6-10,12-15,17,19,27H,4-5,11,16,18H2,(H,28,29)/b24-10+
  • InChiKey: CPFQQGFWCIINTC-YSURURNPSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (E)-6-[4-[2-(benzenesulfonamido)ethyl]phenyl]-6-(3-pyridyl)hex-5-enoic acid
  • (E)-6-[4-[2-(benzenesulfonamido)ethyl]phenyl]-6-(3-pyridyl)-5-hexenoic acid
  • (E)-6-[4-[2-(phenylsulfonylamino)ethyl]phenyl]-6-pyridin-3-yl-hex-5-enoic acid
  • (E)-6-[4-[2-(phenylsulfonylamino)ethyl]phenyl]-6-pyridin-3-ylhex-5-enoic acid
  • (E)-6-[4-[2-(phenylsulfonylamino)ethyl]phenyl]-6-(3-pyridyl)hex-5-enoic acid

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens thromboxane A2 receptor Starlite/ChEMBL References
Homo sapiens thromboxane A synthase 1 (platelet) Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma brucei cytochrome P450, putative thromboxane A synthase 1 (platelet) 534 aa 498 aa 21.5 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi aspartic protease BmAsp-2, identical 0.0058 0.0022 0.0049
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0329 0.0202 0.104
Mycobacterium ulcerans purine nucleoside phosphorylase 0.0056 0.0021 0.0018
Loa Loa (eye worm) G-protein coupled receptor 0.0329 0.0202 0.0476
Onchocerca volvulus 0.0329 0.0202 0.0611
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0047 0.0015 0.0064
Brugia malayi hypothetical protein 0.0164 0.0092 0.0229
Loa Loa (eye worm) hypothetical protein 0.2693 0.1767 0.4223
Brugia malayi Cation transporter family protein 0.0045 0.0014 0.0027
Loa Loa (eye worm) hypothetical protein 0.0045 0.0014 0.0025
Trypanosoma brucei lanosterol synthase 0.0047 0.0015 0.0083
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Plasmodium vivax orotate phosphoribosyltransferase, putative 0.0091 0.0044 0.0035
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0078 0.0035 0.0066
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0042 0.0011 0.002
Mycobacterium tuberculosis Probable pyrimidine operon regulatory protein PyrR 0.0091 0.0044 0.0088
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0045 0.0014 0.0027
Brugia malayi GnHR receptor homolog 0.0329 0.0202 0.051
Echinococcus multilocularis dna polymerase kappa 0.0037 0.0009 0.0015
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0064 0.0026 0.013
Loa Loa (eye worm) hypothetical protein 0.1888 0.1234 0.2947
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0049 0.0017 0.003
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0047 0.0015 0.0066
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0056 0.0021 0.0007
Leishmania major DNA polymerase eta, putative 0.0036 0.0008 0.0041
Loa Loa (eye worm) geranylgeranyl pyrophosphate synthetase 0.0732 0.0469 0.1114
Schistosoma mansoni hypothetical protein 0.0215 0.0126 0.0641
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0054 0.002 0.006
Onchocerca volvulus 0.0038 0.0009 0.0027
Echinococcus granulosus neuropeptide s receptor 0.0603 0.0383 0.0732
Loa Loa (eye worm) cytochrome P450 family protein 0.0061 0.0024 0.005
Loa Loa (eye worm) matrixin family protein 0.559 0.3686 0.8817
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.056 0.0355 0.0677
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0045 0.0014 0.0027
Schistosoma mansoni hypothetical protein 0.0168 0.0095 0.0478
Mycobacterium ulcerans beta-lactamase 0.0038 0.0009 0.0006
Mycobacterium leprae PROBABLE PHOSPHORIBOSYLAMINE--GLYCINE LIGASE PURD (GARS) (GLYCINAMIDE RIBONUCLEOTIDE SYNTHETASE) (PHOSPHORIBOSYLGLYCINAMIDE SYNT 0.0046 0.0014 0.0005
Echinococcus multilocularis lamin 0.0101 0.0051 0.0095
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0034 0.0006 0.0004
Trypanosoma cruzi squalene synthase, putative 0.0264 0.0159 0.0873
Loa Loa (eye worm) hypothetical protein 0.0047 0.0015 0.0028
Brugia malayi RE15519p 0.0329 0.0202 0.051
Schistosoma mansoni glutamate receptor AMPA 0.0136 0.0074 0.0366
Echinococcus multilocularis purine nucleoside phosphorylase 0.0056 0.0021 0.0038
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.012 0.0063 0.0352
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0047 0.0015 0.0066
Loa Loa (eye worm) phosphofructokinase 0.0064 0.0026 0.0055
Onchocerca volvulus 0.0218 0.0128 0.0387
Loa Loa (eye worm) 6-phosphofructokinase 0.0064 0.0026 0.0055
Mycobacterium ulcerans hydrolase 0.2324 0.1523 0.152
Trichomonas vaginalis dihydrofolate synthase/folylpolyglutamate synthase, putative 0.0153 0.0085 0.046
Onchocerca volvulus 0.2898 0.1903 0.5756
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0054 0.0019 0.0091
Echinococcus multilocularis serotonin receptor 0.0329 0.0202 0.0385
Loa Loa (eye worm) hypothetical protein 0.0051 0.0018 0.0035
Trichomonas vaginalis glutamine synthetase-bacteria, putative 0.0245 0.0146 0.08
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.2324 0.1523 0.3049
Echinococcus multilocularis Regulator of G protein signaling 20 0.0031 0.0005 0.0007
Mycobacterium leprae Probable imidazole glycerol-phosphate dehydratase HisB 0.373 0.2454 0.2448
Schistosoma mansoni protein kinase 0.0425 0.0265 0.1374
Treponema pallidum hypothetical protein 0.0091 0.0044 0.0023
Onchocerca volvulus 0.1653 0.1079 0.3263
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0037 0.0008 0.000000000011098
Loa Loa (eye worm) hypothetical protein 0.2555 0.1676 0.4004
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0005 0.0001
Brugia malayi Adenine phosphoribosyltransferase 0.0091 0.0044 0.0105
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0329 0.0202 0.104
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0047 0.0015 0.0054
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0049 0.0016 0.0029
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0054 0.0019 0.0078
Brugia malayi hypothetical protein 0.0383 0.0237 0.0601
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0047 0.0015 0.0082
Loa Loa (eye worm) hypothetical protein 0.0045 0.0014 0.0025
Echinococcus granulosus expressed conserved protein 0.0033 0.0006 0.0009
Brugia malayi Regulator of G protein signaling domain containing protein 0.0031 0.0005 0.0004
Toxoplasma gondii rhoptry neck protein RON9 0.0383 0.0237 0.0229
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0047 0.0015 0.0064
Schistosoma mansoni neuropeptide F-like receptor 0.0329 0.0202 0.104
Toxoplasma gondii 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative 1.5123 1 1
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0074 0.0033 0.0165
Echinococcus granulosus glycine receptor subunit beta 0.0045 0.0014 0.0025
Trypanosoma brucei DNA polymerase eta, putative 0.0036 0.0008 0.0041
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0061 0.0024 0.0044
Mycobacterium leprae PROBABLE FOLYLPOLYGLUTAMATE SYNTHASE PROTEIN FOLC (FOLYLPOLY-GAMMA-GLUTAMATE SYNTHETASE) (FPGS) 0.0153 0.0085 0.0077
Treponema pallidum 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1.5123 1 1
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0045 0.0014 0.0025
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA 0.0218 0.0128 0.0125
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.006 0.0024 0.0015
Onchocerca volvulus 0.0329 0.0202 0.0611
Echinococcus granulosus inosine guanosine and xanthosine phosphorylase 0.0045 0.0013 0.0024
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0009 0.0047
Loa Loa (eye worm) hypothetical protein 0.2555 0.1676 0.4004
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0009 0.0023
Loa Loa (eye worm) hypothetical protein 0.0383 0.0237 0.056
Loa Loa (eye worm) follicle stimulating hormone receptor 0.1073 0.0695 0.1655
Loa Loa (eye worm) glutamate receptor 1 0.0136 0.0074 0.017
Brugia malayi Dopamine receptor protein 1 0.0329 0.0202 0.051
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.0253 0.0152 0.0774
Trypanosoma cruzi farnesyl pyrophosphate synthase 0.2719 0.1784 1
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0329 0.0202 0.0385
Wolbachia endosymbiont of Brugia malayi peptide deformylase 0.0201 0.0117 0.0102
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0037 0.0009 0.0029
Echinococcus multilocularis endothelin converting enzyme 1 0.2555 0.1676 0.3206
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0009 0.0017
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0009 0.0031
Schistosoma mansoni glutamate receptor kainate 0.0136 0.0074 0.0366
Schistosoma mansoni survival motor neuron protein 0.0068 0.0029 0.0128
Trichomonas vaginalis DNA polymerase eta, putative 0.0037 0.0009 0.0029
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.2555 0.1676 0.8804
Treponema pallidum octaprenyl-diphosphate synthase 0.0732 0.0469 0.0448
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0101 0.0051 0.0114
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0074 0.0033 0.0165
Mycobacterium tuberculosis Conserved protein 0.0038 0.0009 0.0017
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0056 0.0021 0.0088
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Loa Loa (eye worm) polyprenyl synthetase 0.0701 0.0448 0.1065
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0009 0.0047
Trypanosoma cruzi folylpolyglutamate synthase, putative 0.0153 0.0085 0.0462
Brugia malayi larval opioid receptor 0.0329 0.0202 0.051
Leishmania major orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative,OMPDCase-OPRTase, putative 0.0091 0.0044 0.0245
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0371 0.023 0.046
Echinococcus multilocularis folylpolyglutamate synthase, mitochondrial 0.0153 0.0085 0.0162
Brugia malayi Cation transporter family protein 0.0045 0.0014 0.0027
Plasmodium falciparum hypoxanthine-guanine phosphoribosyltransferase 0.0388 0.0241 0.0233
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0047 0.0015 0.0082
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0037 0.0008 0.0014
Onchocerca volvulus Matrilysin homolog 0.2123 0.139 0.4203
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0329 0.0202 0.104
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0045 0.0014 0.0025
Echinococcus multilocularis transcription factor Dp 1 0.0031 0.0004 0.0007
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0009 0.0015
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0219 0.0129 0.0705
Loa Loa (eye worm) heterochromatin protein 1 0.0084 0.0039 0.0086
Loa Loa (eye worm) hypothetical protein 0.0049 0.0016 0.0031
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0186 0.0107 0.0582
Brugia malayi hypothetical protein 0.0329 0.0202 0.051
Trypanosoma brucei squalene synthase, putative 0.0264 0.0159 0.0888
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0514 0.0324 0.1683
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0149 0.0083 0.0156
Echinococcus multilocularis somatostatin receptor 0.0329 0.0202 0.0385
Brugia malayi hypothetical protein 0.0058 0.0022 0.0049
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0049 0.0017 0.0032
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0054 0.0019 0.0039
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0078 0.0035 0.0066
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0158 0.0088 0.0086
Echinococcus multilocularis n acetylated alpha linked acidic dipeptidase 2 0.0312 0.019 0.0362
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0065 0.0027 0.0019
Echinococcus granulosus intermediate filament protein 0.0101 0.0051 0.0095
Brugia malayi metabotropic GABA-B receptor subtype 2 0.5913 0.39 1
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0045 0.0014 0.0025
Echinococcus granulosus purine nucleoside phosphorylase 0.0056 0.0021 0.0038
Schistosoma mansoni alpha-glucosidase 0.0081 0.0038 0.0174
Schistosoma mansoni glutamate-cysteine ligase 0.006 0.0023 0.0099
Echinococcus multilocularis tyrosine protein kinase HCK 0.0033 0.0006 0.001
Onchocerca volvulus 0.0045 0.0014 0.0042
Echinococcus granulosus beta-adrenergic receptor kinase 0.0032 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Echinococcus granulosus regulator of G protein signaling 7 0.0031 0.0005 0.0007
Plasmodium vivax hypothetical protein, conserved 0.0081 0.0038 0.0029
Loa Loa (eye worm) hypothetical protein 0.0328 0.0201 0.0474
Echinococcus granulosus bloom syndrome protein 0.0072 0.0032 0.0059
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0514 0.0324 0.0618
Loa Loa (eye worm) TK protein kinase 0.0033 0.0006 0.0007
Loa Loa (eye worm) PXA domain-containing protein 0.0031 0.0005 0.0003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0056 0.0021 0.0101
Trypanosoma cruzi Adenine phosphoribosyltransferase, putative 0.0091 0.0044 0.0229
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0009 0.0032
Plasmodium vivax octaprenyl pyrophosphate synthase, putative 0.0701 0.0448 0.044
Loa Loa (eye worm) neuropeptide F receptor 0.0329 0.0202 0.0476
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0005 0.0006
Schistosoma mansoni hypothetical protein 0.0667 0.0425 0.2217
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0047 0.0015 0.0064
Echinococcus granulosus atrial natriuretic peptide receptor 0.0424 0.0265 0.0505
Trypanosoma brucei protein farnesyltransferase beta subunit 0.0074 0.0033 0.0183
Trypanosoma brucei orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative 0.0091 0.0044 0.0245
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0054 0.002 0.0011
Echinococcus granulosus Regulator of G protein signaling 20 0.0031 0.0005 0.0007
Toxoplasma gondii aminopeptidase n, putative 0.0186 0.0107 0.0099
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0329 0.0202 0.0385
Schistosoma mansoni aldehyde dehydrogenase 0.0049 0.0017 0.0063
Trichomonas vaginalis CMGC family protein kinase 0.0047 0.0015 0.0065
Plasmodium vivax gamma-glutamylcysteine synthetase, putative 0.006 0.0023 0.0014
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0047 0.0015 0.003
Leishmania major hypoxanthine-guanine phosphoribosyltransferase 0.0388 0.0241 0.1348
Loa Loa (eye worm) glutamate receptor 0.1074 0.0695 0.1657
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0186 0.0107 0.058
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0218 0.0128 0.0699
Brugia malayi Dihydrofolate reductase 0.0158 0.0088 0.0219
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0045 0.0014 0.0025
Loa Loa (eye worm) hypothetical protein 0.0424 0.0265 0.0626
Onchocerca volvulus 0.0058 0.0022 0.0067
Loa Loa (eye worm) hypothetical protein 0.1933 0.1264 0.3018
Echinococcus granulosus glutamate cysteine ligase catalytic subunit 0.006 0.0023 0.0043
Echinococcus granulosus nAChR subunit 0.0045 0.0014 0.0025
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.6337 0.4181 1
Brugia malayi Glutamate receptor 1 precursor 0.0136 0.0074 0.0182
Leishmania major trypanothione reductase 0.0163 0.0092 0.0512
Plasmodium vivax aspartyl protease, putative 0.0058 0.0022 0.0013
Loa Loa (eye worm) hypothetical protein 0.1933 0.1264 0.3018
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0058 0.0022 0.0093
Mycobacterium tuberculosis Probable polyprenyl-diphosphate synthase GrcC2 (polyprenyl pyrophosphate synthetase) 0.0701 0.0448 0.0897
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0054 0.0019 0.0107
Onchocerca volvulus Poor gastrulation protein homolog 0.0681 0.0435 0.1315
Loa Loa (eye worm) hypothetical protein 0.1933 0.1264 0.3018
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.2719 0.1784 1
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0186 0.0107 0.0582
Brugia malayi phosphofructokinase 0.0064 0.0026 0.0059
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0047 0.0015 0.0064
Mycobacterium leprae PROBABLE GLUTAMINE SYNTHETASE GLNA2 (GLUTAMINE SYNTHASE) (GS-II) 0.1006 0.065 0.0642
Leishmania major xanthine phosphoribosyltransferase 0.0388 0.0241 0.1348
Mycobacterium ulcerans hypothetical protein 0.0038 0.0009 0.0006
Trypanosoma brucei DNA polymerase IV, putative 0.0033 0.0006 0.0031
Echinococcus multilocularis decaprenyl diphosphate synthase subunit 1 0.0701 0.0448 0.0856
Trypanosoma brucei endonuclease G, putative 0.0047 0.0015 0.0082
Loa Loa (eye worm) hypothetical protein 0.2123 0.139 0.3319
Echinococcus granulosus tyrosine protein kinase Src42A 0.0036 0.0008 0.0013
Schistosoma mansoni chromobox protein 0.0084 0.0039 0.0183
Toxoplasma gondii hypothetical protein 0.0307 0.0187 0.0179
Onchocerca volvulus Matrilysin homolog 0.5016 0.3306 1
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.012 0.0063 0.0352
Entamoeba histolytica protein kinase, putative 0.0033 0.0006 0.0032
Echinococcus granulosus glycine receptor subunit alpha 1 0.0045 0.0014 0.0025
Mycobacterium leprae POSSIBLE OXIDOREDUCTASE 0.0078 0.0035 0.0026
Giardia lamblia Guanine phosphoribosyltransferase 0.0388 0.0241 0.1348
Leishmania major polyprenyl synthase, putative 0.0732 0.0469 0.2626
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0031 0.0005 0.0007
Echinococcus granulosus farnesyl pyrophosphate synthase 0.2719 0.1784 0.3414
Leishmania major glutamine synthetase, putative 0.0519 0.0327 0.1834
Echinococcus granulosus rhodopsin orphan GPCR 0.0329 0.0202 0.0385
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0667 0.0425 0.2217
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0056 0.0021 0.0039
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0078 0.0035 0.0163
Mycobacterium ulcerans aldehyde dehydrogenase 0.0049 0.0017 0.0014
Loa Loa (eye worm) hypothetical protein 0.1105 0.0716 0.1706
Mycobacterium tuberculosis Conserved hypothetical protein 0.0091 0.0044 0.0088
Loa Loa (eye worm) ACC-1 protein 0.0045 0.0014 0.0025
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0009 0.0015
Loa Loa (eye worm) pregnancy-associated plasma protein-E 0.0383 0.0237 0.056
Onchocerca volvulus 0.0101 0.0051 0.0153
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.012 0.0063 0.0054
Loa Loa (eye worm) aminopeptidase N 0.0514 0.0324 0.0768
Plasmodium falciparum thioredoxin reductase 0.0163 0.0092 0.0084
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.2555 0.1676 0.3356
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.056 0.0355 0.0677
Onchocerca volvulus 0.0514 0.0324 0.098
Toxoplasma gondii thioredoxin reductase 0.0163 0.0092 0.0084
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0031 0.0005 0.0006
Echinococcus granulosus tyrosine protein kinase Fyn 0.0042 0.0011 0.002
Plasmodium vivax SET domain protein, putative 0.0061 0.0024 0.0015
Brugia malayi Matrixin family protein 0.2123 0.139 0.3558
Brugia malayi Cation transporter family protein 0.0045 0.0014 0.0027
Giardia lamblia Farnesyl diphosphate synthase 0.2719 0.1784 1
Echinococcus multilocularis glycine receptor subunit beta 0.0045 0.0014 0.0025
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0042 0.0011 0.002
Echinococcus granulosus tm gpcr rhodopsin 0.0329 0.0202 0.0385
Brugia malayi glutamate--cysteine ligase 0.006 0.0023 0.0052
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0024 0.0103
Loa Loa (eye worm) zinc metallopeptidase 4 0.0622 0.0396 0.094
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0045 0.0014 0.0048
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0427 0.0267 0.1477
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0514 0.0324 0.18
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Loa Loa (eye worm) hypothetical protein 0.0038 0.0009 0.0014
Brugia malayi Pre-SET motif family protein 0.0061 0.0024 0.0054
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0078 0.0035 0.0163
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0329 0.0202 0.104
Mycobacterium tuberculosis Possible polyprenyl synthetase IdsB (polyprenyl transferase) (polyprenyl diphosphate synthase) 0.0733 0.0469 0.0939
Echinococcus granulosus glutamate NMDA receptor subunit 0.0234 0.0139 0.0264
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.006 0.0024 0.0016
Echinococcus granulosus glutamate receptor subunit protein glur 0.0072 0.0032 0.0059
Echinococcus granulosus neuropeptides capa receptor 0.0329 0.0202 0.0385
Loa Loa (eye worm) hypothetical protein 0.0045 0.0014 0.0025
Echinococcus granulosus metabotropic glutamate receptor 5 0.2764 0.1814 0.3471
Onchocerca volvulus 0.0329 0.0202 0.0611
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0042 0.0011 0.002
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0158 0.0088 0.008
Mycobacterium leprae Probable purine nucleoside phosphorylase DeoD (INOSINE PHOSPHORYLASE) (PNP) 0.0056 0.0021 0.0012
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0427 0.0267 0.0676
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0034 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Onchocerca volvulus 0.0045 0.0014 0.0042
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0056 0.0021 0.0117
Plasmodium falciparum glutathione reductase 0.0163 0.0092 0.0084
Schistosoma mansoni hypothetical protein 0.0082 0.0038 0.0178
Echinococcus multilocularis rhodopsin orphan GPCR 0.0329 0.0202 0.0385
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0042 0.0011 0.002
Loa Loa (eye worm) hypothetical protein 0.0383 0.0237 0.056
Trypanosoma cruzi gamma-glutamylcysteine synthetase, putative 0.006 0.0023 0.0114
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0329 0.0202 0.0385
Brugia malayi Thioredoxin reductase 0.0163 0.0092 0.0227
Brugia malayi neuropeptide F receptor 0.0329 0.0202 0.051
Toxoplasma gondii endonuclease IV APN 0.026 0.0156 0.0148
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0037 0.0008 0.0012
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0329 0.0202 0.051
Echinococcus multilocularis purine nucleoside phosphorylase 0.0056 0.0021 0.0038
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0186 0.0107 0.0098
Plasmodium falciparum 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1.5123 1 1
Trypanosoma cruzi endonuclease G, putative 0.0047 0.0015 0.0066
Trypanosoma cruzi polypeptide deformylase-like protein, putative 0.0077 0.0035 0.0176
Wolbachia endosymbiont of Brugia malayi orotate phosphoribosyltransferase 0.0091 0.0044 0.003
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0413 0.0257 0.0249
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0045 0.0014 0.0048
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0514 0.0324 0.1801
Plasmodium falciparum plasmepsin V 0.0058 0.0022 0.0014
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0074 0.0033 0.0025
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0045 0.0014 0.0025
Trypanosoma brucei Protein of unknown function (DUF971), putative 0.0081 0.0038 0.0209
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0329 0.0202 0.0385
Echinococcus granulosus neuropeptide receptor 0.0329 0.0202 0.0385
Trypanosoma cruzi Peptide deformylase 2, putative 0.0077 0.0035 0.0176
Loa Loa (eye worm) hypothetical protein 0.114 0.0739 0.176
Onchocerca volvulus 0.0329 0.0202 0.0611
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0032 0.0005 0.001
Brugia malayi AKH receptor 0.0329 0.0202 0.051
Schistosoma mansoni dihydropyridine-sensitive l-type calcium channel 0.01 0.005 0.0238
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Loa Loa (eye worm) peptidase family M13 containing protein 0.1888 0.1234 0.2947
Loa Loa (eye worm) hypothetical protein 0.1888 0.1234 0.2947
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0015 0.0064
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0045 0.0014 0.0048
Loa Loa (eye worm) glutamate-cysteine ligase 0.006 0.0023 0.0048
Echinococcus granulosus lamin 0.0101 0.0051 0.0095
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0009 0.0006
Echinococcus multilocularis g protein coupled receptor 0.0329 0.0202 0.0385
Trypanosoma brucei Adenine phosphoribosyltransferase, putative 0.0091 0.0044 0.0245
Echinococcus multilocularis rhodopsin orphan GPCR 0.0329 0.0202 0.0385
Brugia malayi Metabotropic glutamate receptor precursor. 0.237 0.1554 0.3979
Trypanosoma brucei gamma-glutamylcysteine synthetase 0.006 0.0023 0.013
Brugia malayi ORL1-like opioid receptor 0.0329 0.0202 0.051
Loa Loa (eye worm) hypothetical protein 0.0031 0.0005 0.0003
Schistosoma mansoni 6-phosphofructokinase 0.0064 0.0026 0.0114
Brugia malayi intermediate filament protein 0.0101 0.0051 0.0122
Onchocerca volvulus 0.0329 0.0202 0.0611
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0058 0.0022 0.0093
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0045 0.0014 0.0048
Onchocerca volvulus 0.0058 0.0022 0.0067
Loa Loa (eye worm) hypothetical protein 0.0045 0.0014 0.0025
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.012 0.0063 0.0336
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0329 0.0202 0.0476
Loa Loa (eye worm) melatonin receptor type 1A 0.0329 0.0202 0.0476
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0054 0.0019 0.0041
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.012 0.0063 0.0055
Loa Loa (eye worm) RGC/RGC protein kinase 0.0425 0.0265 0.0628
Leishmania major hypothetical protein, conserved 0.0081 0.0038 0.0209
Plasmodium falciparum M1-family alanyl aminopeptidase 0.0186 0.0107 0.0099
Schistosoma mansoni memapsin-2 (A01 family) 0.0187 0.0108 0.0543
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0041 0.0011 0.0021
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0078 0.0035 0.0066
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Trypanosoma brucei Adenine phosphoribosyltransferase, putative 0.0091 0.0044 0.0245
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Brugia malayi endonuclease G, mitochondrial precursor 0.0047 0.0015 0.003
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0054 0.0019 0.0091
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0329 0.0202 0.0476
Chlamydia trachomatis endonuclease IV 0.026 0.0156 0.0135
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0175 0.01 0.0189
Mycobacterium ulcerans hypothetical protein 0.0069 0.0029 0.0027
Loa Loa (eye worm) hypothetical protein 0.0427 0.0266 0.063
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0371 0.023 0.046
Loa Loa (eye worm) hypothetical protein 0.0032 0.0005 0.0004
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0037 0.0008 0.0014
Brugia malayi hypothetical protein 0.0333 0.0204 0.0516
Loa Loa (eye worm) hypothetical protein 0.0045 0.0014 0.0025
Schistosoma mansoni aminopeptidase A (M01 family) 0.0186 0.0107 0.0538
Echinococcus granulosus neuropeptide Y receptor 0.0329 0.0202 0.0385
Schistosoma mansoni neuropeptide receptor 0.0329 0.0202 0.104
Echinococcus multilocularis regulator of G protein signaling 7 0.0031 0.0005 0.0007
Mycobacterium tuberculosis Probable glutamine synthetase GlnA4 (glutamine synthase) (GS-II) 0.0487 0.0306 0.0613
Trypanosoma cruzi lanosterol synthase, putative 0.0047 0.0015 0.0067
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0015 0.0055
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0156 0.0087 0.0216
Schistosoma mansoni DNA polymerase eta 0.0036 0.0008 0.0016
Wolbachia endosymbiont of Brugia malayi amidophosphoribosyltransferase 0.0091 0.0044 0.003
Echinococcus granulosus 7tm_1 domain containing protein 0.0329 0.0202 0.0385
Echinococcus multilocularis g-protein coupled receptor 0.0329 0.0202 0.0385
Trypanosoma cruzi hypoxanthine-guanine phosphoribosyltransferase, putative 0.0388 0.0241 0.1334
Mycobacterium leprae PROBABLE POLYPEPTIDE DEFORMYLASE DEF (PDF) (FORMYLMETHIONINE DEFORMYLASE) 0.0201 0.0117 0.0108
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0042 0.0011 0.002
Echinococcus multilocularis chromobox protein 1 0.0084 0.0039 0.0073
Echinococcus multilocularis adenine phosphoribosyltransferase 0.0091 0.0044 0.0082
Toxoplasma gondii glutamine synthetase, type I, putative 0.1006 0.065 0.0642
Loa Loa (eye worm) hypothetical protein 0.0101 0.0051 0.0114
Trichomonas vaginalis esterase, putative 0.0038 0.0009 0.0031
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0066 0.0027 0.0051
Mycobacterium ulcerans orotate phosphoribosyltransferase 0.0091 0.0044 0.0041
Onchocerca volvulus Putative folylpolyglutamate synthase 0.0153 0.0085 0.0258
Schistosoma mansoni aldehyde dehydrogenase 0.0049 0.0017 0.0063
Echinococcus multilocularis regulator of G protein signaling 3 0.0031 0.0005 0.0007
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.006 0.0024 0.0132
Echinococcus multilocularis neuropeptide receptor 0.0329 0.0202 0.0385
Echinococcus granulosus g protein coupled receptor 0.0329 0.0202 0.0385
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0047 0.0015 0.0082
Echinococcus granulosus purine nucleoside phosphorylase 0.0056 0.0021 0.0038
Loa Loa (eye worm) hypothetical protein 0.0319 0.0195 0.046
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0042 0.0011 0.002
Wolbachia endosymbiont of Brugia malayi 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1.5123 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0011 0.0043
Mycobacterium tuberculosis Glutamine synthetase GlnA1 (glutamine synthase) (GS-I) 0.0487 0.0306 0.0613
Echinococcus granulosus hypothetical protein 0.0033 0.0006 0.0009
Entamoeba histolytica phosphofructokinase, putative 0.0064 0.0026 0.049
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0037 0.0008 0.0013
Echinococcus multilocularis lysosomal alpha glucosidase 0.0094 0.0046 0.0087
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0034 0.0006 0.0009
Loa Loa (eye worm) TK protein kinase 0.0038 0.0009 0.0013
Brugia malayi PXA domain containing protein 0.0031 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Brugia malayi Peptidase family M1 containing protein 0.0514 0.0324 0.0823
Mycobacterium tuberculosis Probable 1-deoxy-D-xylulose 5-phosphate reductoisomerase Dxr (DXP reductoisomerase) (1-deoxyxylulose-5-phosphate reductoisomeras 0.5803 0.3827 0.7664
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0074 0.0033 0.0165
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0045 0.0014 0.0025
Trypanosoma brucei trypanothione reductase 0.0163 0.0092 0.0512
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0078 0.0035 0.0066
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0015 0.0064
Echinococcus multilocularis chromobox protein 1 0.0084 0.0039 0.0073
Brugia malayi Dopamine receptor 0.0329 0.0202 0.051
Mycobacterium tuberculosis Probable phytoene synthase PhyA 0.0082 0.0038 0.0076
Schistosoma mansoni dihydropyridine-sensitive l-type calcium channel 0.005 0.0017 0.0066
Toxoplasma gondii DNA/RNA non-specific endonuclease 0.0047 0.0015 0.0007
Loa Loa (eye worm) hypothetical protein 0.0045 0.0014 0.0025
Trypanosoma cruzi squalene synthase, putative 0.0264 0.0159 0.0873
Schistosoma mansoni biogenic amine (5HT) receptor 0.0329 0.0202 0.104
Mycobacterium ulcerans adenine phosphoribosyltransferase 0.0091 0.0044 0.0041
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0054 0.0019 0.0107
Brugia malayi hypothetical protein 0.0329 0.0202 0.051
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0427 0.0267 0.0258
Plasmodium vivax thioredoxin reductase, putative 0.0163 0.0092 0.0083
Toxoplasma gondii peptidase family M13 protein 0.2555 0.1676 0.1669
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0413 0.0257 0.0515
Leishmania major adenine phosphoribosyltransferase 0.0091 0.0044 0.0245
Trypanosoma cruzi DNA polymerase kappa, putative 0.0037 0.0009 0.0031
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Echinococcus granulosus geranylgeranyl pyrophosphate synthase 0.0732 0.0469 0.0895
Brugia malayi FolC bifunctional protein 0.0153 0.0085 0.0211
Schistosoma mansoni neuropeptide f receptor 76f 0.0329 0.0202 0.104
Plasmodium falciparum octaprenyl pyrophosphate synthase 0.0701 0.0448 0.044
Mycobacterium ulcerans DNA polymerase IV 0.0037 0.0009 0.0006
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0056 0.0021 0.0117
Loa Loa (eye worm) hypothetical protein 0.0038 0.0009 0.0014
Brugia malayi Heterochromatin protein 1 0.0084 0.0039 0.0093
Loa Loa (eye worm) hypothetical protein 0.0383 0.0237 0.056
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.2324 0.1523 0.39
Echinococcus multilocularis mitogen activated protein kinase 0.0047 0.0015 0.0027
Brugia malayi M-phase phosphoprotein, mpp8 0.0094 0.0046 0.0111
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0054 0.002 0.0036
Leishmania major DNA/RNA non-specific endonuclease-like protein 0.0047 0.0015 0.0082
Onchocerca volvulus 0.0329 0.0202 0.0611
Echinococcus multilocularis lysosomal alpha glucosidase 0.0094 0.0046 0.0087
Loa Loa (eye worm) hypothetical protein 0.0164 0.0092 0.0213
Echinococcus granulosus peptide allatostatin:somatostatin 0.0329 0.0202 0.0385
Mycobacterium leprae PROBABLE POLYPRENYL-DIPHOSPHATE SYNTHASE GRCC1 (POLYPRENYL PYROPHOSPHATE SYNTHETASE) 0.0701 0.0448 0.044
Giardia lamblia Sgs1 DNA helicase, putative 0.0037 0.0008 0.0044
Echinococcus multilocularis glutamate receptor 2 0.0488 0.0307 0.0586
Loa Loa (eye worm) hypothetical protein 0.0038 0.0009 0.0014
Trypanosoma cruzi polypeptide deformylase-like protein, putative 0.0077 0.0035 0.0176
Onchocerca volvulus 0.0045 0.0014 0.0042
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0218 0.0128 0.0699
Echinococcus granulosus adenine phosphoribosyltransferase 0.0091 0.0044 0.0082
Brugia malayi geranylgeranyl pyrophosphate synthetase 0.0732 0.0469 0.1195
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0073 0.0032 0.006
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0042 0.0011 0.002
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0045 0.0014 0.0027
Schistosoma mansoni biogenic amine receptor 0.0329 0.0202 0.104
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.234 0.1533 0.8053
Loa Loa (eye worm) hypothetical protein 0.0046 0.0014 0.0027
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0329 0.0202 0.104
Echinococcus multilocularis lamin dm0 0.0101 0.0051 0.0095
Schistosoma mansoni hypothetical protein 0.2898 0.1903 1
Brugia malayi Thrombospondin type 1 domain containing protein 0.0168 0.0095 0.0236
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0005 0.0006
Brugia malayi 6-phosphofructokinase 0.0064 0.0026 0.0059
Echinococcus granulosus purine nucleoside phosphorylase 0.0056 0.0021 0.0038
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0218 0.0128 0.0699
Mycobacterium ulcerans folylpolyglutamate synthase protein FolC 0.0153 0.0085 0.0083
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0514 0.0324 0.0618
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0329 0.0202 0.104
Schistosoma mansoni hypothetical protein 0.0149 0.0083 0.0411
Schistosoma mansoni glutamine synthetase bacteria 0.0732 0.0469 0.2444
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Echinococcus granulosus G protein coupled receptor 139 0.0329 0.0202 0.0385
Trichomonas vaginalis chromobox protein, putative 0.0084 0.0039 0.0201
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0056 0.0021 0.0117
Plasmodium vivax aspartyl protease, putative 0.0058 0.0022 0.0013
Trypanosoma brucei endonuclease G, putative 0.0047 0.0015 0.0082
Echinococcus granulosus leukotriene A 4 hydrolase 0.0253 0.0152 0.0288
Echinococcus multilocularis tyrosine protein kinase Srms 0.0038 0.0009 0.0015
Brugia malayi hypothetical protein 0.0383 0.0237 0.0601
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0034 0.0006 0.0033
Trypanosoma cruzi DNA/RNA non-specific endonuclease protein-like, putative 0.0047 0.0015 0.0066
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0056 0.0021 0.0013
Loa Loa (eye worm) hypothetical protein 0.0045 0.0014 0.0025
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0045 0.0014 0.0025
Schistosoma mansoni family M1 non-peptidase homologue (M01 family) 0.0328 0.0201 0.1035
Mycobacterium tuberculosis Probable dehydrogenase 0.0371 0.023 0.046
Brugia malayi purine nucleoside phosphorylase I, inosine and guanosine-specific family protein 0.0056 0.0021 0.0046
Onchocerca volvulus Putative nachr subunit 0.0045 0.0014 0.0042
Schistosoma mansoni hypothetical protein 0.0667 0.0425 0.2217
Brugia malayi TATA binding protein associated factor 0.0186 0.0107 0.0266
Brugia malayi Polyprenyl synthetase family protein 0.0701 0.0448 0.1142
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0015 0.0064
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0045 0.0014 0.0025
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0054 0.0019 0.0333
Echinococcus multilocularis fmrfamide receptor 0.0329 0.0202 0.0385
Echinococcus granulosus uridine 5' monophosphate synthase 0.0091 0.0044 0.0082
Giardia lamblia NADH oxidase lateral transfer candidate 0.0056 0.0021 0.0117
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0034 0.0006 0.001
Onchocerca volvulus 0.0383 0.0237 0.0718
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0514 0.0324 0.1814
Plasmodium vivax apical sushi protein, putative 0.0383 0.0237 0.0229
Mycobacterium tuberculosis Probable folylpolyglutamate synthase protein FolC (folylpoly-gamma-glutamate synthetase) (FPGS) 0.0153 0.0085 0.0171
Brugia malayi Sushi domain 0.0383 0.0237 0.0601
Mycobacterium tuberculosis Probable imidazole glycerol-phosphate dehydratase HisB 0.7564 0.4994 1
Echinococcus multilocularis G protein coupled receptor 139 0.0329 0.0202 0.0385
Trichomonas vaginalis chromobox protein, putative 0.0054 0.002 0.0092
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.012 0.0063 0.0154
Brugia malayi Cache domain containing protein 0.0046 0.0014 0.0029
Trypanosoma cruzi lanosterol synthase, putative 0.0047 0.0015 0.0067
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0045 0.0014 0.0048
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0701 0.0448 0.2498
Onchocerca volvulus 0.0329 0.0202 0.0611
Onchocerca volvulus 0.0045 0.0014 0.0042
Toxoplasma gondii glutamate-cysteine ligase, catalytic subunit domain-containing protein 0.006 0.0023 0.0015
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0068 0.0029 0.0066
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0045 0.0014 0.0027
Loa Loa (eye worm) SRC-1 0.0042 0.0011 0.002
Schistosoma mansoni Adenine phosphoribosyltransferase 0.0091 0.0044 0.0208
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0061 0.0024 0.0044
Mycobacterium ulcerans bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase 0.0091 0.0044 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0005 0.0006
Onchocerca volvulus 0.0068 0.0029 0.0087
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0009 0.0017
Loa Loa (eye worm) hypothetical protein 0.0038 0.0009 0.0014
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.012 0.0063 0.0119
Mycobacterium tuberculosis Conserved protein 0.0038 0.0009 0.0017
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0058 0.0022 0.0093
Onchocerca volvulus 0.0329 0.0202 0.0611
Brugia malayi Serotonin receptor 0.0329 0.0202 0.051
Trypanosoma brucei hypoxanthine-guanine phosphoribosyltransferase 0.0388 0.0241 0.1348
Trypanosoma brucei aminopeptidase, putative 0.0186 0.0107 0.0597
Schistosoma mansoni nAChR subunit 0.0045 0.0014 0.0048
Entamoeba histolytica glutamine synthetase, putative 0.0245 0.0146 0.3188
Onchocerca volvulus 0.0329 0.0202 0.0611
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0156 0.0087 0.0165
Loa Loa (eye worm) glutathione reductase 0.0163 0.0092 0.0212
Trichomonas vaginalis phosphofructokinase, putative 0.0064 0.0026 0.0128
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0156 0.0087 0.1863
Trypanosoma cruzi gamma-glutamylcysteine synthetase, putative 0.006 0.0023 0.0114
Loa Loa (eye worm) hypothetical protein 0.2764 0.1814 0.4335
Plasmodium falciparum plasmepsin III 0.0058 0.0022 0.0014
Echinococcus granulosus purine nucleoside phosphorylase 0.0056 0.0021 0.0038
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0078 0.0035 0.0163
Mycobacterium ulcerans polyprenyl diphosphate synthetase, GrcC1 0.0701 0.0448 0.0446
Echinococcus multilocularis g protein coupled receptor 0.0329 0.0202 0.0385
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Loa Loa (eye worm) hypothetical protein 0.0425 0.0265 0.0628
Onchocerca volvulus NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 homolog 0.0082 0.0038 0.0116
Brugia malayi Dopamine receptor protein 2 0.0329 0.0202 0.051
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0049 0.0016 0.0029
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0156 0.0087 0.0435
Toxoplasma gondii aspartyl protease ASP1 0.0219 0.0129 0.0121
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.026 0.0156 0.0148
Schistosoma mansoni amine GPCR 0.0329 0.0202 0.104
Brugia malayi Peptidase family M1 containing protein 0.1653 0.1079 0.276
Schistosoma mansoni glutamate receptor NMDA 0.0607 0.0386 0.2007
Echinococcus multilocularis glutamate receptor NMDA 0.0046 0.0015 0.0026
Loa Loa (eye worm) hypothetical protein 0.0078 0.0035 0.0077
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Schistosoma mansoni hypothetical protein 0.0667 0.0425 0.2217
Trypanosoma cruzi DNA polymerase kappa, putative 0.0037 0.0009 0.0031
Plasmodium falciparum apical sushi protein 0.0383 0.0237 0.0229
Brugia malayi sulfakinin receptor protein 0.0427 0.0266 0.0675
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0047 0.0015 0.0082
Schistosoma mansoni nAChR subunit 0.0045 0.0014 0.0048
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0218 0.0128 0.2782
Brugia malayi putative neuropeptide receptor NPR1 0.0329 0.0202 0.051
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0045 0.0014 0.0027
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0328 0.0201 0.0383
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0064 0.0026 0.0052
Echinococcus multilocularis neutral sphingomyelinase 0.0035 0.0007 0.0012
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0045 0.0014 0.0025
Schistosoma mansoni DNA helicase recq5 0.0037 0.0008 0.0019
Trypanosoma brucei cytochrome P450, putative 0.0029 0.0003 0.0016
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0329 0.0202 0.0385
Brugia malayi chromobox protein homolog 3 0.0051 0.0018 0.0037
Loa Loa (eye worm) hypothetical protein 0.0424 0.0265 0.0626
Plasmodium vivax hypoxanthine-guanine phosphoribosyltransferase, putative 0.0388 0.0241 0.0232
Brugia malayi Melatonin receptor type 1A 0.0329 0.0202 0.051
Loa Loa (eye worm) RGS-3 protein 0.0031 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.0036 0.0008 0.0011
Mycobacterium leprae PROBABLE OROTATE PHOSPHORIBOSYLTRANSFERASE PYRE (OPRT) (OPRTASE) 0.0091 0.0044 0.0035
Mycobacterium leprae AMIDOPHOSPHORIBOSYLTRANSFERASE PURF (GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE) (ATASE) (GPATASE) 0.0091 0.0044 0.0035
Echinococcus multilocularis c4b binding protein beta chain 0.0383 0.0237 0.0452
Trichomonas vaginalis ribose-phosphate pyrophosphokinase, putative 0.0091 0.0044 0.0228
Echinococcus granulosus nmda type glutamate receptor 0.0221 0.0131 0.0248
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.014 0.0077 0.038
Toxoplasma gondii bifunctional protein FolC subfamily protein 0.0153 0.0085 0.0077
Schistosoma mansoni glutamate receptor AMPA 0.0136 0.0074 0.0366
Trypanosoma brucei protein kinase, putative 0.0047 0.0015 0.0082
Schistosoma mansoni hypothetical protein 0.0054 0.0019 0.0078
Echinococcus multilocularis dro:myosuppressin receptor 0.0329 0.0202 0.0385
Schistosoma mansoni tyrosine kinase 0.0042 0.0011 0.0036
Schistosoma mansoni opsin-like receptor 0.0329 0.0202 0.104
Loa Loa (eye worm) hypothetical protein 0.0031 0.0005 0.0003
Echinococcus multilocularis beta adrenergic receptor kinase 0.0032 0.0005 0.0007
Schistosoma mansoni histamine h1 receptor 0.0329 0.0202 0.104
Schistosoma mansoni neuropeptide F-like receptor 0.0329 0.0202 0.104
Loa Loa (eye worm) hypothetical protein 0.0186 0.0107 0.0248
Brugia malayi Phosphoribosyl transferase domain containing protein 0.0388 0.0241 0.061
Echinococcus granulosus neuropeptide receptor A26 0.0603 0.0383 0.0732
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0514 0.0324 0.0618
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0047 0.0015 0.0066
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0056 0.0021 0.0007
Echinococcus multilocularis nmda type glutamate receptor 0.0471 0.0295 0.0564
Schistosoma mansoni purine nucleoside phosphorylase 0.0056 0.0021 0.0087
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0061 0.0024 0.0044
Brugia malayi metabotropic glutamate receptor type 2 0.1498 0.0976 0.2497
Echinococcus multilocularis mitogen activated protein kinase 3 0.0047 0.0015 0.0027
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0329 0.0202 0.0476
Trypanosoma cruzi aminopeptidase, putative 0.0514 0.0324 0.1801
Onchocerca volvulus 0.0082 0.0038 0.0116
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.1048 0.0678 0.3548
Entamoeba histolytica phosphofructokinase, putative 0.0064 0.0026 0.049
Mycobacterium tuberculosis Possible exported protein 0.016 0.009 0.0179
Mycobacterium ulcerans phytoene synthase, CrtB 0.0082 0.0038 0.0036
Schistosoma mansoni hypothetical protein 0.0329 0.0202 0.104
Brugia malayi hypothetical protein 0.0171 0.0097 0.0242
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0064 0.0026 0.0017
Mycobacterium ulcerans glutamine synthetase 0.1006 0.065 0.0647
Echinococcus multilocularis conserved hypothetical protein 0.0033 0.0006 0.0009
Trypanosoma cruzi farnesyl pyrophosphate synthase, putative 0.2719 0.1784 1
Loa Loa (eye worm) matrix metalloproteinase 0.2123 0.139 0.3319
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0056 0.0021 0.0101
Trypanosoma cruzi hypoxanthine-guanine phosphoribosyltransferase, putative 0.0388 0.0241 0.1334
Schistosoma mansoni hypothetical protein 0.0329 0.0202 0.104
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0046 0.0015 0.0006
Trypanosoma brucei DNA polymerase IV, putative 0.0037 0.0009 0.0047
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0514 0.0324 0.0618
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0056 0.0021 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0005 0.0006
Mycobacterium tuberculosis Conserved protein 0.0091 0.0044 0.0088
Loa Loa (eye worm) hypothetical protein 0.1933 0.1264 0.3018
Leishmania major extracellular receptor, putative 0.0424 0.0265 0.1482
Echinococcus multilocularis survival motor neuron protein 1 0.0333 0.0204 0.0389
Echinococcus granulosus glycine receptor subunit alpha 1 0.0045 0.0014 0.0025
Brugia malayi G-protein coupled receptor 0.0329 0.0202 0.051
Echinococcus multilocularis 6 phosphofructokinase 0.0064 0.0026 0.0048
Leishmania major farnesyltransferase beta subunit 0.0074 0.0033 0.0183
Trichomonas vaginalis chromobox protein, putative 0.0054 0.002 0.0092
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0045 0.0014 0.0025
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0034 0.0006 0.0004
Echinococcus multilocularis uridine 5' monophosphate synthase 0.0091 0.0044 0.0082
Echinococcus granulosus tyrosine protein kinase HCK 0.0033 0.0006 0.001
Brugia malayi MAP kinase sur-1 0.0047 0.0015 0.003
Echinococcus multilocularis thioredoxin glutathione reductase 0.0163 0.0092 0.0174
Brugia malayi beta-lactamase family protein 0.0038 0.0009 0.0015
Echinococcus granulosus aminopeptidase N 0.1653 0.1079 0.2063
Schistosoma mansoni hypothetical protein 0.0667 0.0425 0.2217
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0329 0.0202 0.104
Echinococcus granulosus biogenic amine 5HT receptor 0.0329 0.0202 0.0385
Echinococcus multilocularis neuropeptide s receptor 0.0603 0.0383 0.0732
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.0009 0.0014
Plasmodium vivax dihydrofolate synthase/folylpolyglutamate synthase, putative 0.0153 0.0085 0.0077
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0329 0.0202 0.104
Echinococcus granulosus rhodopsin orphan GPCR 0.0329 0.0202 0.0385
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0009 0.0047
Onchocerca volvulus 0.0383 0.0237 0.0718
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0031 0.0005 0.0003
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0056 0.0021 0.0042
Mycobacterium tuberculosis Amidophosphoribosyltransferase PurF (glutamine phosphoribosylpyrophosphate amidotransferase) (ATASE) (gpatase) 0.0091 0.0044 0.0088
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0047 0.0015 0.0064
Mycobacterium ulcerans endonuclease IV 0.026 0.0156 0.0154
Trypanosoma cruzi hypoxanthine-guanine phosphoribosyltransferase, putative 0.0388 0.0241 0.1334
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0011 0.0043
Echinococcus multilocularis rhodopsin orphan GPCR 0.0329 0.0202 0.0385
Schistosoma mansoni Tata binding protein associated factor (M01 family) 0.0186 0.0107 0.0538
Schistosoma mansoni biogenic amine (5HT) receptor 0.0329 0.0202 0.104
Trichomonas vaginalis phosphofructokinase, putative 0.0064 0.0026 0.0128
Schistosoma mansoni intermediate filament proteins 0.0101 0.0051 0.0243
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0514 0.0324 0.0618
Brugia malayi Bloom's syndrome protein homolog 0.0072 0.0032 0.0074
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0042 0.0011 0.002
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.0681 0.0435 0.1315
Schistosoma mansoni tyrosine kinase 0.0042 0.0011 0.0036
Chlamydia trachomatis glutamine binding protein 0.0103 0.0052 0.0031
Echinococcus granulosus rhodopsin orphan GPCR 0.0329 0.0202 0.0385
Mycobacterium ulcerans aldehyde dehydrogenase 0.0049 0.0017 0.0014
Onchocerca volvulus 0.0038 0.0009 0.0027
Schistosoma mansoni amine GPCR 0.0329 0.0202 0.104
Echinococcus granulosus GPCR family 3 C terminal 0.0681 0.0435 0.0831
Leishmania major folylpolyglutamate synthetase 0.0153 0.0085 0.0477
Trypanosoma brucei Polypeptide deformylase 1 0.0077 0.0035 0.0192
Brugia malayi hypothetical protein 0.0031 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0383 0.0237 0.056
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0078 0.0035 0.0066
Echinococcus multilocularis purine nucleoside phosphorylase 0.0056 0.0021 0.0038
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0514 0.0324 0.0618
Trypanosoma brucei glutamine synthetase, putative 0.0519 0.0327 0.1834
Entamoeba histolytica aminopeptidase, putative 0.0514 0.0324 0.72
Trichomonas vaginalis hypoxanthine-guanine phosphoribosyltransferase, putative 0.0388 0.0241 0.1333
Brugia malayi Peptidase family M1 containing protein 0.0186 0.0107 0.0266
Schistosoma mansoni metabotropic glutamate receptor 0.1689 0.1103 0.5785
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0042 0.0011 0.002
Schistosoma mansoni glutamine synthetase bacteria 0.0732 0.0469 0.2444
Schistosoma mansoni adenoreceptor 0.0329 0.0202 0.104
Mycobacterium leprae PROBABLE HYDROLASE 0.2324 0.1523 0.1515
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.1289 0.0838 0.4388
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0074 0.0033 0.0165
Plasmodium vivax plasmepsin V, putative 0.0058 0.0022 0.0013
Trypanosoma brucei hypoxanthine-guanine phosphoribosyltransferase, putative 0.0388 0.0241 0.1348
Onchocerca volvulus 0.0329 0.0202 0.0611
Echinococcus granulosus 7TM GPCR rhodopsin 0.0329 0.0202 0.0385
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0009 0.0014
Schistosoma mansoni endonuclease related 0.0047 0.0015 0.0054
Echinococcus granulosus neuropeptide Y receptor 0.0329 0.0202 0.0385
Echinococcus granulosus purine nucleoside phosphorylase 0.0056 0.0021 0.0038
Plasmodium falciparum conserved protein, unknown function 0.0081 0.0038 0.0029
Trypanosoma cruzi polyprenyl synthase, putative 0.0732 0.0469 0.2614
Brugia malayi hypothetical protein 0.0095 0.0046 0.0111
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0047 0.0015 0.0064
Echinococcus multilocularis dna polymerase eta 0.0036 0.0008 0.0013
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0329 0.0202 0.104
Echinococcus multilocularis folylpolyglutamate synthase, mitochondrial 0.0153 0.0085 0.0162
Trichomonas vaginalis phosphofructokinase, putative 0.0064 0.0026 0.0128
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.026 0.0156 0.0313
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0191 0.011 0.0556
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.2719 0.1784 1
Loa Loa (eye worm) hypothetical protein 0.1933 0.1264 0.3018
Leishmania major endonuclease G, putative 0.0047 0.0015 0.0082
Onchocerca volvulus 0.0388 0.0241 0.0729
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0056 0.0021 0.0117
Leishmania major puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0186 0.0107 0.0597
Brugia malayi jmjC domain containing protein 0.0061 0.0024 0.0054
Brugia malayi hypothetical protein 0.0329 0.0202 0.051
Loa Loa (eye worm) hypothetical protein 0.0054 0.002 0.004
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0047 0.0015 0.0027
Mycobacterium ulcerans glutamine synthetase GlnA1 0.1006 0.065 0.0647
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0056 0.0021 0.0117
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0103 0.0052 0.0031
Echinococcus multilocularis farnesyl pyrophosphate synthase 0.2719 0.1784 0.3414
Echinococcus multilocularis neuropeptide Y receptor 0.0329 0.0202 0.0385
Schistosoma mansoni glutathione synthetase 0.0701 0.0448 0.2337
Loa Loa (eye worm) Gln-2 protein 0.0519 0.0327 0.0776
Echinococcus granulosus axis inhibition protein axin 0.0031 0.0005 0.0007
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0514 0.0324 0.18
Mycobacterium leprae GLUTAMINE SYNTHETASE GLNA1 (GLUTAMINE SYNTHASE) (Glutamate--ammonia ligase 1) (GS-I) 0.0487 0.0306 0.0298
Echinococcus granulosus tyrosine protein kinase Src64B 0.0042 0.0011 0.002
Trypanosoma cruzi polyprenyl synthase, putative 0.0732 0.0469 0.2614
Echinococcus granulosus fmrfamide receptor 0.0329 0.0202 0.0385
Brugia malayi SRC-1 0.0042 0.0011 0.0021
Echinococcus granulosus nmda type glutamate receptor 0.0471 0.0295 0.0564
Chlamydia trachomatis geranylgeranyl pyrophosphate synthase 0.0733 0.0469 0.0449
Loa Loa (eye worm) hypothetical protein 0.0186 0.0107 0.0248
Loa Loa (eye worm) glutamate receptor 0.237 0.1554 0.3712
Trypanosoma cruzi trypanothione reductase, putative 0.0056 0.0021 0.0101
Mycobacterium ulcerans imidazoleglycerol-phosphate dehydratase 0.7564 0.4994 0.4992
Onchocerca volvulus Putative neutral sphingomyelinase 0.0035 0.0007 0.0022
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0056 0.0021 0.0101
Brugia malayi Serotonin receptor 0.0329 0.0202 0.051
Trypanosoma cruzi aminopeptidase, putative 0.0186 0.0107 0.0582
Echinococcus multilocularis g protein coupled receptor 0.0329 0.0202 0.0385
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0045 0.0014 0.0027
Loa Loa (eye worm) hypothetical protein 0.0078 0.0035 0.0077
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0047 0.0015 0.0066
Mycobacterium ulcerans 6-phosphofructokinase 0.0064 0.0026 0.0024
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0072 0.0032 0.0059
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0329 0.0202 0.104
Echinococcus granulosus thioredoxin glutathione reductase 0.0163 0.0092 0.0174
Schistosoma mansoni opsin-like receptor 0.0329 0.0202 0.104
Brugia malayi hypothetical protein 0.0329 0.0202 0.051
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0329 0.0202 0.104
Mycobacterium tuberculosis Probable reductase 0.0371 0.023 0.046
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0069 0.0029 0.0088
Onchocerca volvulus Glutamine synthetase homolog 0.0519 0.0327 0.0991
Schistosoma mansoni c4b-binding protein beta chain 0.0383 0.0237 0.1226
Trypanosoma brucei hypoxanthine-guanine phosphoribosyltransferase 0.0388 0.0241 0.1348
Trypanosoma cruzi trypanothione reductase, putative 0.0163 0.0092 0.0497
Echinococcus multilocularis rhodopsin orphan GPCR 0.0329 0.0202 0.0385
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0329 0.0202 0.051
Giardia lamblia Adenine phosphoribosyltransferase 0.0091 0.0044 0.0245
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0329 0.0202 0.104
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0037 0.0008 0.0014
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0156 0.0087 0.0216
Schistosoma mansoni amine GPCR 0.0329 0.0202 0.104
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0047 0.0015 0.0064
Plasmodium falciparum glutathione reductase 0.0056 0.0021 0.0013
Toxoplasma gondii aspartyl protease 0.0058 0.0022 0.0014
Mycobacterium leprae PROBABLE 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE DXR (DXP REDUCTOISOMERASE) (1-DEOXYXYLULOSE-5-PHOSPHATE REDUCTOISOMERAS 1.5123 1 1
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.056 0.0355 0.0677
Leishmania major farnesyl pyrophosphate synthase 0.2719 0.1784 1
Loa Loa (eye worm) hypothetical protein 0.2555 0.1676 0.4004
Mycobacterium tuberculosis Probable dioxygenase 0.0078 0.0035 0.007
Leishmania major lanosterol synthase, putative 0.0027 0.0002 0.0008
Treponema pallidum folylpolyglutamate synthetase (folC) 0.0153 0.0085 0.0064
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0047 0.0015 0.0028
Brugia malayi Guanylyl cyclase protein 23 0.0425 0.0265 0.0673
Mycobacterium tuberculosis Probable geranylgeranyl pyrophosphate synthetase IdsA2 (ggppsase) (GGPP synthetase) (geranylgeranyl diphosphate synthase) 0.2719 0.1784 0.3573
Loa Loa (eye worm) hypothetical protein 0.0045 0.0014 0.0025
Trypanosoma cruzi Aminopeptidase M1, putative 0.0514 0.0324 0.1801
Onchocerca volvulus 0.0078 0.0035 0.0107
Loa Loa (eye worm) hypothetical protein 0.0424 0.0265 0.0626
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0061 0.0024 0.0016
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0044 0.0013 0.0072
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0156 0.0087 0.0472
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0424 0.0265 0.0505
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0329 0.0202 0.0385
Schistosoma mansoni metabotropic glutamate receptor 0.1498 0.0976 0.5118
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase 0.0218 0.0128 0.0716
Echinococcus multilocularis sex peptide receptor 0.0329 0.0202 0.0385
Echinococcus granulosus lysosomal alpha glucosidase 0.0094 0.0046 0.0087
Loa Loa (eye worm) thrombospondin type 1 domain-containing protein 0.0168 0.0095 0.022
Onchocerca volvulus 0.0383 0.0237 0.0718
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0066 0.0027 0.0051
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0045 0.0014 0.0027
Mycobacterium leprae probable zinc metalloprotease 0.2555 0.1676 0.1668
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0622 0.0396 0.2062
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0035 0.0007 0.0011
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0218 0.0128 0.0699
Echinococcus granulosus dna polymerase eta 0.0036 0.0008 0.0013
Entamoeba histolytica bifunctional short chain isoprenyl diphosphate synthase, putative 0.0701 0.0448 1
Mycobacterium ulcerans zinc metalloprotease 0.2555 0.1676 0.1674
Schistosoma mansoni folylpolyglutamate synthase 0.0153 0.0085 0.0426
Trichomonas vaginalis CMGC family protein kinase 0.0047 0.0015 0.0065
Echinococcus granulosus tachykinin peptides receptor 99D 0.0329 0.0202 0.0385
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Schistosoma mansoni alpha-glucosidase 0.0081 0.0038 0.0174
Schistosoma mansoni hypothetical protein 0.0068 0.0029 0.0128
Schistosoma mansoni DNA helicase recq1 0.0037 0.0008 0.0019
Trichomonas vaginalis chromobox protein, putative 0.0084 0.0039 0.0201
Mycobacterium ulcerans hypothetical protein 0.0091 0.0044 0.0041
Entamoeba histolytica phosphofructokinase, putative 0.0064 0.0026 0.049
Echinococcus multilocularis purine nucleoside phosphorylase 0.0056 0.0021 0.0038
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0058 0.0022 0.0093
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0156 0.0087 0.0201
Echinococcus granulosus dro:myosuppressin receptor 0.0329 0.0202 0.0385
Echinococcus multilocularis receptor type guanylyl cyclase 0.0425 0.0265 0.0506
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0047 0.0015 0.0064
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0015 0.0064
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0078 0.0035 0.0066
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0329 0.0202 0.0385
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0034 0.0006 0.0012
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0218 0.0128 0.2782
Trypanosoma cruzi phytoene synthase, putative 0.0082 0.0038 0.0198
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0036 0.0008 0.0013
Mycobacterium ulcerans 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1.5123 1 1
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0056 0.0021 0.0101
Trypanosoma cruzi hypoxanthine-guanine phosphoribosyltransferase, putative 0.0388 0.0241 0.1334
Loa Loa (eye worm) G-protein coupled receptor 0.0329 0.0202 0.0476
Brugia malayi hypothetical protein 0.0514 0.0324 0.0823
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.012 0.0063 0.0336
Loa Loa (eye worm) hypothetical protein 0.0164 0.0092 0.0213
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0034 0.0006 0.0008
Brugia malayi Low molecular weight phosphotyrosine protein phosphatase containing protein 0.0218 0.0128 0.032
Schistosoma mansoni neuropeptide receptor 0.0329 0.0202 0.104
Echinococcus granulosus ectonucleotide 0.0066 0.0027 0.0051
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0045 0.0014 0.0025
Loa Loa (eye worm) hypothetical protein 0.0038 0.0009 0.0014
Mycobacterium tuberculosis Probable purine nucleoside phosphorylase DeoD (inosine phosphorylase) (PNP) 0.0056 0.0021 0.0042
Loa Loa (eye worm) hypothetical protein 0.0186 0.0107 0.0248
Onchocerca volvulus 0.0168 0.0095 0.0288
Brugia malayi hypothetical protein 0.0186 0.0107 0.0266
Schistosoma mansoni nAChR subunit 0.0045 0.0014 0.0048
Onchocerca volvulus 0.0383 0.0237 0.0718
Giardia lamblia Prenyltransferase 0.0074 0.0033 0.0183
Onchocerca volvulus 0.0483 0.0304 0.0918
Echinococcus multilocularis metabotropic glutamate receptor 5 0.2764 0.1814 0.3471
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0045 0.0014 0.0027
Onchocerca volvulus 0.0383 0.0237 0.0718
Schistosoma mansoni trans-prenyltransferase 0.0701 0.0448 0.2337
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.056 0.0355 0.0677
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0015 0.0064
Trypanosoma cruzi endonuclease G, putative 0.0047 0.0015 0.0066
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0047 0.0015 0.0064
Trichomonas vaginalis glutathione reductase, putative 0.0056 0.0021 0.01
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0329 0.0202 0.104
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0058 0.0022 0.0014
Echinococcus granulosus axis inhibition protein axin 0.0031 0.0005 0.0007
Loa Loa (eye worm) FolC protein 0.0153 0.0085 0.0197
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0514 0.0324 0.1814
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0329 0.0202 0.0385
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0056 0.0021 0.0117
Loa Loa (eye worm) hypothetical protein 0.0045 0.0014 0.0025
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0051 0.0018 0.0053
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0156 0.0087 0.0472
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0032 0.0005 0.0004
Echinococcus granulosus hypoxanthine guanine phosphoribosyltransferase 0.0388 0.0241 0.0459
Brugia malayi Cytochrome P450 family protein 0.0061 0.0024 0.0053
Schistosoma mansoni nAChR subunit 0.0045 0.0014 0.0048
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0329 0.0202 0.0385
Plasmodium vivax aspartyl proteinase, putative 0.0219 0.0129 0.012
Echinococcus granulosus rhodopsin orphan GPCR 0.0329 0.0202 0.0385
Echinococcus granulosus orexin receptor type 2 0.0329 0.0202 0.0385
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Loa Loa (eye worm) hypothetical protein 0.0045 0.0013 0.0024
Schistosoma mansoni thyroid hormone receptor 0.0161 0.0091 0.0453
Toxoplasma gondii hypothetical protein 0.0201 0.0117 0.0109
Brugia malayi Pepsin A precursor 0.0058 0.0022 0.0049
Brugia malayi beta-lactamase 0.0038 0.0009 0.0015
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Leishmania major solanesyl-diphosphate synthase, putative 0.0701 0.0448 0.251
Echinococcus multilocularis neuropeptide Y receptor 0.0329 0.0202 0.0385
Onchocerca volvulus 0.0329 0.0202 0.0611
Echinococcus granulosus allatostatin A receptor 0.0329 0.0202 0.0385
Brugia malayi excitatory GABA receptor EXP-1A 0.0045 0.0014 0.0027
Echinococcus granulosus tyrosine kinase 0.0425 0.0265 0.0506
Onchocerca volvulus 0.0329 0.0202 0.0611
Schistosoma mansoni tyrosine kinase 0.0425 0.0265 0.1374
Giardia lamblia Purine nucleoside phosphorylase lateral transfer candidate 0.0056 0.0021 0.0116
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0029 0.0003 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0005 0.0006
Echinococcus multilocularis regulator of G protein signaling 3 0.0031 0.0005 0.0007
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0094 0.0046 0.0103
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0047 0.0015 0.0064
Echinococcus granulosus glutamate receptor NMDA 0.0046 0.0015 0.0026
Brugia malayi Hemopexin family protein 0.2898 0.1903 0.4875
Echinococcus multilocularis GPCR, family 3, C terminal 0.0681 0.0435 0.0831
Schistosoma mansoni hypothetical protein 0.0329 0.0202 0.104
Loa Loa (eye worm) hypothetical protein 0.1266 0.0822 0.196
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0011 0.0043
Trypanosoma cruzi extracellular receptor, putative 0.0424 0.0265 0.1468
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0072 0.0032 0.0059
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0371 0.023 0.046
Echinococcus granulosus tm gpcr rhodopsin 0.0329 0.0202 0.0385
Loa Loa (eye worm) hypothetical protein 0.0383 0.0237 0.056
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0009 0.0015
Echinococcus multilocularis allatostatin A receptor 0.0329 0.0202 0.0385
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0047 0.0015 0.0064
Echinococcus granulosus protein prenyltransferase alpha subunit 0.012 0.0063 0.0119
Echinococcus granulosus mitogen activated protein kinase 3 0.0047 0.0015 0.0027
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0058 0.0022 0.0093
Brugia malayi glutathione reductase 0.0163 0.0092 0.0227
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0056 0.0021 0.0117
Trichomonas vaginalis DNA helicase recq1, putative 0.0072 0.0032 0.0159
Brugia malayi hypothetical protein 0.0031 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0424 0.0265 0.0626
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0032 0.0005 0.0004
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0047 0.0015 0.0066
Onchocerca volvulus 0.0094 0.0046 0.014
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.0074 0.0033 0.0165
Echinococcus multilocularis neuropeptides capa receptor 0.0329 0.0202 0.0385
Echinococcus granulosus tyrosine protein kinase Src42A 0.0042 0.0011 0.002
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0078 0.0035 0.0066
Trypanosoma brucei Aminopeptidase M1, putative 0.0514 0.0324 0.1814
Echinococcus multilocularis glutamate receptor 2 0.0136 0.0074 0.014
Trichomonas vaginalis phosphofructokinase, putative 0.0064 0.0026 0.0128
Echinococcus multilocularis glycine receptor subunit beta 0.0045 0.0014 0.0025
Echinococcus granulosus sex peptide receptor 0.0329 0.0202 0.0385
Loa Loa (eye worm) hypothetical protein 0.0082 0.0038 0.0084
Mycobacterium tuberculosis Probable multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 (GGPP synthetase) (ggppsase) (geranylgeranyl diphosphate 0.0733 0.0469 0.0939
Toxoplasma gondii aspartyl protease ASP3 0.0058 0.0022 0.0014
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0058 0.0022 0.0093
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0058 0.0022 0.0046
Trypanosoma cruzi Protein of unknown function (DUF971), putative 0.0081 0.0038 0.0193
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0329 0.0202 0.104
Echinococcus multilocularis G-protein coupled receptor, putative 0.0329 0.0202 0.0385
Mycobacterium ulcerans aminopeptidase N PepN 0.0186 0.0107 0.0104
Echinococcus granulosus regulator of G protein signaling 3 0.0031 0.0005 0.0007
Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferase 0.0388 0.0241 0.1245
Schistosoma mansoni lamin 0.0101 0.0051 0.0243
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0045 0.0014 0.0025
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0329 0.0202 0.104
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.026 0.0156 0.0393
Plasmodium falciparum protein farnesyltransferase subunit beta 0.0074 0.0033 0.0025
Echinococcus granulosus protein farnesyltransferase subunit beta 0.0074 0.0033 0.0061
Schistosoma mansoni protein farnesyltransferase subunit beta 0.0074 0.0033 0.0149
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0015 0.0064
Loa Loa (eye worm) hypothetical protein 0.0045 0.0014 0.0025
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0045 0.0014 0.0027
Schistosoma mansoni biogenic amine receptor 0.0329 0.0202 0.104
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Loa Loa (eye worm) hypothetical protein 0.0383 0.0237 0.056
Loa Loa (eye worm) leukotriene A4 hydrolase 0.0253 0.0152 0.0355
Echinococcus granulosus dna polymerase kappa 0.0037 0.0009 0.0015
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Echinococcus multilocularis prenyl (decaprenyl) diphosphate synthase 0.0701 0.0448 0.0856
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0329 0.0202 0.0385
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0701 0.0448 0.044
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0082 0.0038 0.0178
Echinococcus granulosus hypothetical protein 0.0329 0.0202 0.0385
Plasmodium vivax 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative 1.5123 1 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0005 0.0003
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.006 0.0024 0.0116
Echinococcus granulosus voltage dependent calcium channel subunit 0.0104 0.0053 0.0099
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0483 0.0304 0.0579
Echinococcus granulosus alpha 1A adrenergic receptor 0.0329 0.0202 0.0385
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0329 0.0202 0.104
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0047 0.0015 0.0064
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0045 0.0014 0.0027
Onchocerca volvulus 0.0383 0.0237 0.0718
Schistosoma mansoni hypothetical protein 0.0329 0.0202 0.104
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0047 0.0015 0.0064
Echinococcus granulosus neuropeptide FF receptor 2 0.0329 0.0202 0.0385
Schistosoma mansoni geranylgeranyl pyrophosphate synthase 0.0732 0.0469 0.2445
Plasmodium falciparum plasmepsin I 0.0219 0.0129 0.0121
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0186 0.0107 0.0203
Echinococcus granulosus histone lysine methyltransferase setb 0.0061 0.0024 0.0044
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Leishmania major protein farnesyltransferase alpha subunit, putative 0.012 0.0063 0.0352
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0156 0.0087 0.0079
Toxoplasma gondii aldehyde dehydrogenase 0.0049 0.0017 0.0008
Chlamydia trachomatis peptide deformylase 0.0201 0.0117 0.0096
Loa Loa (eye worm) LGC-31 protein 0.0045 0.0014 0.0025
Echinococcus granulosus glycine receptor subunit alpha 1 0.0045 0.0014 0.0025
Loa Loa (eye worm) hypothetical protein 0.0099 0.0049 0.0111
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0078 0.0035 0.0163
Trichomonas vaginalis mercuric reductase, putative 0.0056 0.0021 0.01
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0514 0.0325 0.1686
Mycobacterium ulcerans taurine catabolism dioxygenase, TauD 0.0078 0.0035 0.0033
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0047 0.0015 0.0066
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0186 0.0107 0.0597
Schistosoma mansoni cathepsin D (A01 family) 0.0631 0.0402 0.2092
Echinococcus granulosus nuclear factor of activated T cells 5 0.0079 0.0036 0.0067
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.1946 0.1273 0.3259
Echinococcus granulosus mitogen activated protein kinase 0.0047 0.0015 0.0027
Schistosoma mansoni hypothetical protein 0.0681 0.0435 0.2267
Plasmodium vivax farnesyltransferase beta subunit, putative 0.0074 0.0033 0.0024
Mycobacterium tuberculosis Probable polypeptide deformylase Def (PDF) (formylmethionine deformylase) 0.0201 0.0117 0.0233
Onchocerca volvulus 0.0329 0.0202 0.0611
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0427 0.0267 0.0259
Schistosoma mansoni Nep2 peptidase (M13 family) 0.1289 0.0838 0.4388
Trypanosoma cruzi protein farnesyltransferase, putative 0.0074 0.0033 0.0167
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Echinococcus multilocularis axis inhibition protein axin 0.0031 0.0005 0.0007
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0219 0.0129 0.0656
Mycobacterium tuberculosis Possible oxidoreductase 0.0078 0.0035 0.007
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0329 0.0202 0.0611
Mycobacterium tuberculosis Probable oxidoreductase 0.0413 0.0257 0.0515
Toxoplasma gondii ABC1 family protein 0.0038 0.0009 0.0001
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0782 0.0501 0.2617
Leishmania major hypothetical protein, conserved 0.0082 0.0038 0.0213
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0103 0.0052 0.0031
Brugia malayi Matrixin family protein 0.2123 0.139 0.3558
Echinococcus granulosus purine nucleoside phosphorylase 0.0056 0.0021 0.0038
Echinococcus granulosus folylpolyglutamate synthase mitochondrial 0.0153 0.0085 0.0162
Brugia malayi Receptor family ligand binding region containing protein 0.3168 0.2082 0.5334
Brugia malayi ImpB/MucB/SamB family protein 0.0036 0.0008 0.0011
Echinococcus multilocularis expressed conserved protein 0.0033 0.0006 0.0009
Giardia lamblia Rab geranylgeranyltransferase 0.0427 0.0267 0.1492
Mycobacterium tuberculosis Probable lipoprotein aminopeptidase LpqL 0.0028 0.0003 0.0005
Brugia malayi pregnancy-associated plasma protein-A 0.0383 0.0237 0.0601
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0045 0.0014 0.0025
Toxoplasma gondii rhoptry neck protein RON1 0.0383 0.0237 0.0229
Echinococcus granulosus tyrosine kinase 0.0038 0.0009 0.0015
Brugia malayi Matrixin family protein 0.2123 0.139 0.3558
Onchocerca volvulus 0.0164 0.0092 0.0279
Mycobacterium ulcerans hypothetical protein 0.0487 0.0306 0.0304
Plasmodium falciparum orotate phosphoribosyltransferase 0.0091 0.0044 0.0036
Mycobacterium tuberculosis Probable glutamine synthetase GlnA2 (glutamine synthase) (GS-II) 0.1006 0.065 0.1301
Loa Loa (eye worm) hypothetical protein 0.0424 0.0265 0.0626
Mycobacterium ulcerans hypothetical protein 0.0245 0.0146 0.0143
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0329 0.0202 0.104
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0056 0.0021 0.0012
Brugia malayi aspartic protease BmAsp-1, identical 0.0058 0.0022 0.0049
Echinococcus multilocularis axis inhibition protein axin 0.0031 0.0005 0.0007
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0186 0.0107 0.0582
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0072 0.0032 0.0059
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0015 0.0064
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0009 0.0047
Loa Loa (eye worm) hypothetical protein 0.0045 0.0014 0.0025
Plasmodium falciparum plasmepsin VII 0.0058 0.0022 0.0014
Loa Loa (eye worm) hypothetical protein 0.0383 0.0237 0.056
Echinococcus multilocularis expressed protein 0.0609 0.0387 0.0739
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.012 0.0063 0.0336
Loa Loa (eye worm) hypothetical protein 0.0038 0.0009 0.0014
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0329 0.0202 0.0385
Loa Loa (eye worm) hypothetical protein 0.1888 0.1234 0.2947
Loa Loa (eye worm) hypothetical protein 0.1933 0.1264 0.3018
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.7914 0.5225 1
Trypanosoma brucei hypothetical protein, conserved 0.012 0.0063 0.0352
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0073 0.0032 0.0145
Leishmania major ATP-dependent phosphofructokinase 0.0064 0.0026 0.0146
Schistosoma mansoni neuropeptide receptor 0.0329 0.0202 0.104
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0069 0.0029 0.0067
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0044 0.0013 0.0072
Plasmodium vivax geranylgeranyl pyrophosphate synthase 0.2719 0.1784 0.1777
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.1289 0.0838 0.4388
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0371 0.023 0.046
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0056 0.0021 0.0101
Onchocerca volvulus 0.0425 0.0265 0.0803
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0514 0.0324 0.0618
Schistosoma mansoni thyroid hormone receptor 0.0161 0.0091 0.0453
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0072 0.0032 0.0059
Loa Loa (eye worm) RGC/RGC protein kinase 0.0425 0.0265 0.0628
Plasmodium vivax glutamine synthetase, putative 0.1006 0.065 0.0642
Echinococcus multilocularis nmda type glutamate receptor 0.0221 0.0131 0.0248
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0049 0.0017 0.0091
Echinococcus granulosus glycine receptor subunit beta 0.0045 0.0014 0.0025
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0015 0.0064
Echinococcus multilocularis purine nucleoside phosphorylase 0.0056 0.0021 0.0038
Leishmania major dihydrofolate reductase-thymidylate synthase 0.006 0.0024 0.0132
Schistosoma mansoni neprilysin 0.0667 0.0425 0.2217
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0056 0.0021 0.0046
Schistosoma mansoni neuropeptide receptor 0.0329 0.0202 0.104
Entamoeba histolytica geranylgeranyl pyrophosphate synthetase, putative 0.0701 0.0448 1
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0041 0.0011 0.0021
Trypanosoma cruzi DNA polymerase kappa, putative 0.0037 0.0009 0.0031
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0032 0.0005 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0009 0.0032
Echinococcus granulosus Squalene phytoene synthase 0.0082 0.0038 0.0072
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0219 0.0129 0.0121
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0009 0.0017
Echinococcus multilocularis Endonuclease G 0.0047 0.0015 0.0027
Trypanosoma cruzi solanesyl-diphosphate synthase 0.0701 0.0448 0.2498
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0009 0.0047
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0424 0.0265 0.0626
Loa Loa (eye worm) dihydrofolate reductase 0.0158 0.0088 0.0204
Plasmodium falciparum plasmepsin IX 0.0058 0.0022 0.0014
Echinococcus granulosus purine nucleoside phosphorylase 0.0056 0.0021 0.0038
Trypanosoma cruzi Adenine phosphoribosyltransferase, putative 0.0091 0.0044 0.0229
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0074 0.0033 0.0076
Plasmodium vivax peptide deformylase, putative 0.0201 0.0117 0.0108
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0015 0.0064
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0056 0.0021 0.0019
Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferase 0.0091 0.0044 0.0208
Schistosoma mansoni glutamine synthetase 1 2 (glutamate-amonia ligase) (gs) 0.0519 0.0327 0.1701
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0054 0.002 0.0036
Trypanosoma cruzi folylpolyglutamate synthetase 0.0153 0.0085 0.0462
Giardia lamblia Rab geranylgeranyltransferase 0.012 0.0063 0.0352
Schistosoma mansoni polycystin 1-related 0.0052 0.0018 0.0072
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0328 0.0201 0.1111
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0009 0.0006
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0413 0.0257 0.0515
Echinococcus granulosus neutral sphingomyelinase 0.0035 0.0007 0.0012
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0032 0.0005 0.0009
Treponema pallidum methyl-accepting chemotaxis protein (mcp2-1) 0.0211 0.0124 0.0103
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.7914 0.5225 1
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0078 0.0035 0.0066
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0156 0.0087 0.0487
Echinococcus multilocularis glutamine synthetase 0.0519 0.0327 0.0625
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Schistosoma mansoni blooms syndrome DNA helicase 0.0054 0.0019 0.0078
Loa Loa (eye worm) hypothetical protein 0.0094 0.0046 0.0103
Loa Loa (eye worm) hypothetical protein 0.0035 0.0007 0.001
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.2719 0.1784 0.1782
Schistosoma mansoni glutamate receptor kainate 0.0136 0.0074 0.0366
Onchocerca volvulus Purine nucleoside phosphorylase homolog 0.0056 0.0021 0.0064
Loa Loa (eye worm) hypothetical protein 0.2123 0.139 0.3319
Schistosoma mansoni nAChR subunit 0.0045 0.0014 0.0048
Echinococcus granulosus regulator of G protein signaling 7 0.0031 0.0005 0.0007
Schistosoma mansoni cathepsin D (A01 family) 0.0631 0.0402 0.2092
Trypanosoma cruzi Protein of unknown function (DUF971), putative 0.0081 0.0038 0.0193
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Brugia malayi dihydrofolate reductase family protein 0.0158 0.0088 0.0219
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0015 0.0064
Echinococcus multilocularis geranylgeranyl pyrophosphate synthase 0.0732 0.0469 0.0895
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0079 0.0036 0.0067
Wolbachia endosymbiont of Brugia malayi extracellular metallopeptidase 0.0373 0.0231 0.0217
Plasmodium falciparum M1-family alanyl aminopeptidase, putative 0.0186 0.0107 0.0099
Onchocerca volvulus 0.0383 0.0237 0.0718
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0047 0.0015 0.0082
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0009 0.0031
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.3168 0.2082 0.4976
Echinococcus multilocularis purine nucleoside phosphorylase 0.0056 0.0021 0.0038
Mycobacterium tuberculosis Conserved hypothetical protein 0.0487 0.0306 0.0613
Brugia malayi Receptor family ligand binding region containing protein 0.0425 0.0265 0.0673
Echinococcus granulosus dihydrofolate reductase 0.0158 0.0088 0.0167
Echinococcus granulosus chromobox protein 1 0.0084 0.0039 0.0073
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0103 0.0052 0.0049
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0023 0.0042
Echinococcus granulosus g protein coupled receptor 0.0329 0.0202 0.0385
Echinococcus granulosus glutamine synthetase 0.0519 0.0327 0.0625
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0009 0.0023
Echinococcus granulosus rhodopsin orphan GPCR 0.0329 0.0202 0.0385
Trypanosoma brucei farnesyl pyrophosphate synthase 0.2719 0.1784 1
Trichomonas vaginalis geranylgeranyl diphosphate synthase, putative 0.2719 0.1784 1
Toxoplasma gondii hypoxanthine-xanthine-guanine phosphoribosyl transferase HXGPRT 0.0388 0.0241 0.0233
Plasmodium vivax glutathione reductase, putative 0.0163 0.0092 0.0083
Echinococcus granulosus tyrosine protein kinase Blk 0.0038 0.0009 0.0015
Trypanosoma brucei unspecified product 0.0033 0.0006 0.0031
Onchocerca volvulus 0.1266 0.0822 0.2487
Trichomonas vaginalis DNA helicase recq, putative 0.0044 0.0013 0.0054
Schistosoma mansoni microtubule-associated protein tau 0.0931 0.0601 0.314
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.0074 0.0033 0.0638
Brugia malayi regulator of G-protein signaling egl-10 0.0031 0.0005 0.0004
Echinococcus granulosus purine nucleoside phosphorylase 0.0056 0.0021 0.0038
Loa Loa (eye worm) hypothetical protein 0.0045 0.0014 0.0025
Schistosoma mansoni dihydrofolate reductase 0.0158 0.0088 0.0442
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0156 0.0087 0.0078
Onchocerca volvulus 0.0094 0.0046 0.014
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0371 0.023 0.0221
Mycobacterium tuberculosis Probable orotate phosphoribosyltransferase PyrE (OPRT) (oprtase) 0.0091 0.0044 0.0088
Loa Loa (eye worm) hypothetical protein 0.0031 0.0005 0.0003
Onchocerca volvulus 0.0383 0.0237 0.0718
Loa Loa (eye worm) hypothetical protein 0.0058 0.0022 0.0046
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0219 0.0129 0.0245
Schistosoma mansoni Adenine phosphoribosyltransferase 0.0091 0.0044 0.0208
Echinococcus multilocularis fmrfamide receptor 0.0329 0.0202 0.0385
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.056 0.0355 0.0677
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0514 0.0324 0.1814
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0156 0.0087 0.0201
Echinococcus granulosus rhodopsin orphan GPCR 0.0329 0.0202 0.0385
Mycobacterium ulcerans lipase LipD 0.0038 0.0009 0.0006
Loa Loa (eye worm) hypothetical protein 0.026 0.0156 0.0367
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0103 0.0052 0.0103
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Echinococcus granulosus C type lectin domian containing protein 0.0383 0.0237 0.0452
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0038 0.0009 0.0015
Brugia malayi hypothetical protein 0.0383 0.0237 0.0601
Schistosoma mansoni tyrosine kinase 0.0425 0.0265 0.1374
Echinococcus granulosus geminin 0.0215 0.0126 0.024
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.006 0.0024 0.0016
Loa Loa (eye worm) intermediate filament protein 0.0101 0.0051 0.0114
Giardia lamblia Kinase, CMGC MAPK 0.0047 0.0015 0.0082
Onchocerca volvulus 0.0383 0.0237 0.0718
Schistosoma mansoni lamin 0.0101 0.0051 0.0243
Echinococcus multilocularis rhodopsin orphan GPCR 0.0329 0.0202 0.0385
Echinococcus granulosus transcription factor Dp 1 0.0031 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0045 0.0014 0.0025
Plasmodium falciparum dihydrofolate synthase/folylpolyglutamate synthase 0.0153 0.0085 0.0077
Mycobacterium tuberculosis Conserved hypothetical protein 0.0069 0.0029 0.0058
Brugia malayi Matrixin family protein 0.559 0.3686 0.9452
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0045 0.0014 0.0025
Plasmodium falciparum peptide deformylase 0.0201 0.0117 0.0109
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.2719 0.1784 0.1782
Leishmania major gamma-glutamylcysteine synthetase, putative 0.006 0.0023 0.013
Loa Loa (eye worm) matrixin family protein 0.4446 0.2929 0.7002
Schistosoma mansoni neprilysin-2 (M13 family) 0.1289 0.0838 0.4388
Loa Loa (eye worm) hypothetical protein 0.0031 0.0005 0.0003
Brugia malayi hypothetical protein 0.0427 0.0266 0.0675
Echinococcus multilocularis tyrosine kinase 0.0425 0.0265 0.0506
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0064 0.0026 0.0146
Brugia malayi hypothetical protein 0.0383 0.0237 0.0601
Loa Loa (eye worm) hypothetical protein 0.0383 0.0237 0.056
Loa Loa (eye worm) beta-lactamase 0.0038 0.0009 0.0014
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0064 0.0026 0.0005
Loa Loa (eye worm) hypothetical protein 0.1467 0.0956 0.228
Toxoplasma gondii hypothetical protein 0.0041 0.0011 0.0003
Schistosoma mansoni jumonji domain containing protein 0.0048 0.0016 0.0059
Brugia malayi Matrixin family protein 0.2123 0.139 0.3558
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0015 0.0064
Brugia malayi hypothetical protein 0.0329 0.0202 0.051
Echinococcus multilocularis C type lectin domian containing protein 0.0383 0.0237 0.0452
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.2693 0.1767 0.9286
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0056 0.0021 0.0013
Schistosoma mansoni purine nucleoside phosphorylase 0.0056 0.0021 0.0087
Loa Loa (eye worm) hypothetical protein 0.0427 0.0267 0.063
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0044 0.0013 0.0056
Loa Loa (eye worm) ACC-1 protein 0.0045 0.0014 0.0025
Brugia malayi hypothetical protein 0.0329 0.0202 0.051
Trichomonas vaginalis glutamine synthetase, putative 0.0245 0.0146 0.08
Brugia malayi Pre-SET motif family protein 0.0424 0.0265 0.0671
Trypanosoma brucei Aminopeptidase M1, putative 0.0514 0.0324 0.1814
Schistosoma mansoni hypothetical protein 0.0667 0.0425 0.2217
Echinococcus granulosus c4b binding protein beta chain 0.0383 0.0237 0.0452
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0047 0.0015 0.0064
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0045 0.0014 0.0025
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0156 0.0087 0.0471
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0009 0.0017
Loa Loa (eye worm) hypothetical protein 0.0045 0.0014 0.0025
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0032 0.0005 0.0004
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0015 0.0064
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.026 0.0156 0.0148
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.026 0.0156 0.0148
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0018 0.008
Trypanosoma cruzi hypothetical protein, conserved 0.012 0.0063 0.0336
Loa Loa (eye worm) hypothetical protein 0.0045 0.0014 0.0025
Echinococcus granulosus Endonuclease G 0.0047 0.0015 0.0027
Treponema pallidum phosphoribosylpyrophosphate synthetase 0.0091 0.0044 0.0023
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0701 0.0448 0.2498
Loa Loa (eye worm) hypothetical protein 0.0033 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0045 0.0014 0.0025
Brugia malayi PXA domain containing protein 0.0031 0.0005 0.0004
Mycobacterium ulcerans amidophosphoribosyltransferase 0.0091 0.0044 0.0041
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0015 0.0064
Loa Loa (eye worm) polyprenyl synthetase 0.2719 0.1784 0.4264
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0047 0.0015 0.0066
Schistosoma mansoni biogenic amine receptor 0.0329 0.0202 0.104
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0329 0.0202 0.0385
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0156 0.0087 0.0471
Plasmodium falciparum gamma-glutamylcysteine synthetase 0.006 0.0023 0.0015
Loa Loa (eye worm) hypothetical protein 0.0446 0.028 0.0662
Schistosoma mansoni orotidine 5'-phosphate decarboxylase 0.0091 0.0044 0.0208
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0218 0.0128 0.0699
Loa Loa (eye worm) hypothetical protein 0.0291 0.0176 0.0415
Trypanosoma cruzi glutamine synthetase, putative 0.0519 0.0327 0.1821
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0427 0.0267 0.0508
Trypanosoma cruzi DNA polymerase kappa, putative 0.0037 0.0009 0.0031
Trypanosoma brucei Peptide deformylase 2 0.0077 0.0035 0.0192
Trichomonas vaginalis CMGC family protein kinase 0.0047 0.0015 0.0065
Onchocerca volvulus 0.2123 0.139 0.4203
Loa Loa (eye worm) glutamate receptor 2 0.0136 0.0074 0.017
Onchocerca volvulus Neuropeptide F receptor homolog 0.0329 0.0202 0.0611
Loa Loa (eye worm) hypothetical protein 0.0078 0.0035 0.0077
Loa Loa (eye worm) hypothetical protein 0.0061 0.0024 0.005
Echinococcus multilocularis regulator of G protein signaling 0.0031 0.0005 0.0007
Echinococcus granulosus tyrosine protein kinase Fyn 0.0042 0.0011 0.002
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.012 0.0063 0.0352
Mycobacterium tuberculosis Adenine phosphoribosyltransferase Apt (APRT) (AMP diphosphorylase) (AMP pyrophosphorylase) (transphosphoribosidase) 0.0091 0.0044 0.0088
Loa Loa (eye worm) TATA binding protein associated factor 0.0186 0.0107 0.0248
Loa Loa (eye worm) hypothetical protein 0.0045 0.0014 0.0025
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0427 0.0267 0.1477
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0045 0.0014 0.0027
Echinococcus multilocularis glutamate receptor 2 0.056 0.0355 0.0677
Schistosoma mansoni lipoxygenase 0.0054 0.002 0.0079
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0329 0.0202 0.0385
Brugia malayi Glutamate receptor 2 precursor 0.0136 0.0074 0.0182
Onchocerca volvulus 0.0038 0.0009 0.0027
Brugia malayi hypothetical protein 0.0058 0.0022 0.0049
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0047 0.0015 0.0027
Schistosoma mansoni glutamate receptor kainate 0.0136 0.0074 0.0366
Echinococcus multilocularis rhodopsin orphan GPCR 0.0329 0.0202 0.0385
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.056 0.0355 0.0677
Trichomonas vaginalis Ribose-phosphate pyrophosphokinase, putative 0.0091 0.0044 0.0228
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.1289 0.0838 0.4388
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0042 0.0011 0.002
Onchocerca volvulus Matrix metalloproteinase homolog 0.4446 0.2929 0.8858
Schistosoma mansoni chromobox protein 0.0084 0.0039 0.0183
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0009 0.0047
Echinococcus multilocularis neuropeptides capa receptor 0.0329 0.0202 0.0385
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0024 0.0103
Echinococcus granulosus glutamate receptor 2 0.0488 0.0307 0.0586
Echinococcus multilocularis musashi 0.0101 0.0051 0.0095
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0024 0.0103
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0078 0.0035 0.0066
Loa Loa (eye worm) hypothetical protein 0.0424 0.0265 0.0626
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Echinococcus multilocularis serotonin receptor 0.0329 0.0202 0.0385
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0218 0.0128 0.0699
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0156 0.0087 0.0079
Schistosoma mansoni farnesyl pyrophosphate synthase 0.2719 0.1784 0.9376
Brugia malayi A-kinase anchor protein 10, precursor 0.0031 0.0005 0.0004
Brugia malayi Type I phosphodiesterase / nucleotide pyrophosphatase family protein 0.0078 0.0035 0.0083
Echinococcus multilocularis dihydrofolate reductase 0.0158 0.0088 0.0167
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0072 0.0032 0.0059
Onchocerca volvulus 0.0424 0.0265 0.0801
Brugia malayi GCC2 and GCC3 family protein 0.0383 0.0237 0.0601
Trichomonas vaginalis set domain proteins, putative 0.0483 0.0304 0.1685
Echinococcus granulosus g protein coupled receptor 0.0329 0.0202 0.0385
Schistosoma mansoni growth hormone secretagogue receptor 0.0329 0.0202 0.104
Loa Loa (eye worm) hypothetical protein 0.0058 0.0022 0.0046
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0045 0.0014 0.0025
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0045 0.0014 0.0027
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0073 0.0032 0.006
Loa Loa (eye worm) thioredoxin reductase 0.0163 0.0092 0.0212
Loa Loa (eye worm) hypothetical protein 0.0219 0.0129 0.0301
Entamoeba histolytica hypothetical protein 0.0424 0.0265 0.5863
Schistosoma mansoni amine GPCR 0.0329 0.0202 0.104
Echinococcus multilocularis hypoxanthine guanine phosphoribosyltransferase 0.0388 0.0241 0.0459
Mycobacterium tuberculosis Probable glutamine synthetase GlnA3 (glutamine synthase) (GS-I) 0.0732 0.0469 0.0938
Brugia malayi beta-lactamase family protein 0.0038 0.0009 0.0015
Schistosoma mansoni hypothetical protein 0.0215 0.0126 0.0641
Onchocerca volvulus 0.0078 0.0035 0.0107
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0329 0.0202 0.051
Leishmania major cytochrome p450-like protein 0.0029 0.0003 0.0016
Trypanosoma cruzi orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative 0.0091 0.0044 0.0229
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0009 0.0049
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0427 0.0267 0.0508
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0158 0.0088 0.0177
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0056 0.0021 0.0101
Treponema pallidum polypeptide deformylase (def) 0.0201 0.0117 0.0096
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0329 0.0202 0.104
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.012 0.0063 0.0119
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0056 0.0021 0.0117
Loa Loa (eye worm) aspartyl protease 6 0.0058 0.0022 0.0046
Mycobacterium tuberculosis Conserved protein 0.0038 0.0009 0.0017
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0009 0.0031
Loa Loa (eye worm) hypothetical protein 0.0045 0.0014 0.0025
Echinococcus multilocularis ectonucleotide 0.0066 0.0027 0.0051
Echinococcus multilocularis aminopeptidase N 0.1653 0.1079 0.2063
Leishmania major hypothetical protein, conserved 0.0038 0.0009 0.0049
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) 0.0218 0.0128 0.0256
Schistosoma mansoni neutral sphingomyelinase 0.0035 0.0007 0.0014
Onchocerca volvulus 0.0045 0.0014 0.0042
Onchocerca volvulus 0.0101 0.0051 0.0153
Loa Loa (eye worm) hypothetical protein 0.0333 0.0204 0.0481
Brugia malayi G-protein coupled receptor 0.0329 0.0202 0.051
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0058 0.0022 0.0093
Loa Loa (eye worm) hypothetical protein 0.0383 0.0237 0.056
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0329 0.0202 0.051
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0009 0.0017
Onchocerca volvulus 0.0329 0.0202 0.0611
Chlamydia trachomatis dihydrofolate reductase 0.0158 0.0088 0.0067
Plasmodium vivax plasmepsin IV, putative 0.0219 0.0129 0.012
Trypanosoma cruzi Adenine phosphoribosyltransferase, putative 0.0091 0.0044 0.0229
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0329 0.0202 0.0385
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0058 0.0022 0.0093
Schistosoma mansoni alpha-1 adrenergic receptor 0.0329 0.0202 0.104
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0701 0.0448 0.0434
Echinococcus granulosus microtubule associated protein 2 0.0931 0.0601 0.1148
Mycobacterium ulcerans hypoxanthine-guanine phosphoribosyltransferase Hpt 0.0388 0.0241 0.0238
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0186 0.0107 0.0582
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0037 0.0008 0.0013
Loa Loa (eye worm) hypothetical protein 0.0037 0.0008 0.0012
Echinococcus granulosus lamin dm0 0.0101 0.0051 0.0095
Trichomonas vaginalis DNA helicase recq, putative 0.0072 0.0032 0.0159
Schistosoma mansoni ATP-binding cassette transporter 0.0136 0.0074 0.0366
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0329 0.0202 0.0385
Echinococcus multilocularis hypoxanthine guanine phosphoribosyltransferase 0.0388 0.0241 0.0459
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0329 0.0202 0.0385
Brugia malayi G protein-coupled receptor F59B2.13 0.0329 0.0202 0.051
Plasmodium falciparum glutamine synthetase, putative 0.1006 0.065 0.0642
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0072 0.0032 0.0059
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0622 0.0396 0.2062
Brugia malayi Eukaryotic aspartyl protease family protein 0.0058 0.0022 0.0049
Schistosoma mansoni opsin-like receptor 0.0329 0.0202 0.104
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0054 0.002 0.0039
Toxoplasma gondii aminopeptidase N, putative 0.0186 0.0107 0.0099
Echinococcus granulosus prenyl decaprenyl diphosphate synthase 0.0701 0.0448 0.0856
Echinococcus granulosus tyrosine protein kinase Lyn 0.0042 0.0012 0.0021
Schistosoma mansoni NAALADASE L peptidase (M28 family) 0.0204 0.0119 0.0603
Entamoeba histolytica geranylgeranyl pyrophosphate synthase, putative 0.0701 0.0448 1
Mycobacterium ulcerans DNA polymerase IV 0.0037 0.0009 0.0006
Plasmodium falciparum geranylgeranyl pyrophosphate synthase, putative 0.2719 0.1784 0.1778
Loa Loa (eye worm) hypothetical protein 0.0095 0.0046 0.0104
Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferase 0.0091 0.0044 0.0208
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0045 0.0014 0.0025
Brugia malayi hypothetical protein 0.0068 0.0029 0.0065
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0031 0.0005 0.0007
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0037 0.0008 0.0014
Loa Loa (eye worm) hypothetical protein 0.0045 0.0014 0.0025
Echinococcus granulosus regulator of G protein signaling 3 0.0031 0.0005 0.0007
Brugia malayi Regulator of G protein signaling domain containing protein 0.0031 0.0005 0.0004
Mycobacterium ulcerans aminopeptidase N PepN 0.0514 0.0324 0.0321
Toxoplasma gondii orotate phosphoribosyltransferase 0.0091 0.0044 0.0036
Loa Loa (eye worm) hypothetical protein 0.0047 0.0015 0.0028
Schistosoma mansoni uracil phosphoribosyltransferase 0.0091 0.0044 0.0208
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.056 0.0355 0.0677
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0032 0.0005 0.0009
Brugia malayi 6-phosphofructokinase 0.0064 0.0026 0.0059
Brugia malayi hypothetical protein 0.0424 0.0265 0.0671
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0047 0.0015 0.0007
Echinococcus multilocularis NMDA receptor 0.0072 0.0032 0.0059
Loa Loa (eye worm) neuropeptide F receptor 0.0329 0.0202 0.0476
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0186 0.0107 0.0203
Echinococcus granulosus somatostatin receptor 0.0329 0.0202 0.0385
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0047 0.0015 0.0006
Trypanosoma brucei DNA polymerase IV, putative 0.0037 0.0009 0.0047
Schistosoma mansoni myosin xvIII 0.0329 0.0202 0.104
Brugia malayi hypothetical protein 0.0383 0.0237 0.0601
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0514 0.0324 0.0618
Brugia malayi neuropeptide F receptor 0.0329 0.0202 0.051
Echinococcus granulosus decaprenyl diphosphate synthase subunit 1 0.0701 0.0448 0.0856
Trypanosoma cruzi DNA polymerase eta, putative 0.0036 0.0008 0.0025
Schistosoma mansoni amine GPCR 0.0329 0.0202 0.104
Loa Loa (eye worm) hypothetical protein 0.0031 0.0005 0.0003
Trypanosoma cruzi Adenine phosphoribosyltransferase, putative 0.0091 0.0044 0.0229
Schistosoma mansoni endothelin-converting enzyme-related 0.0622 0.0396 0.2062
Mycobacterium ulcerans aldehyde dehydrogenase 0.0049 0.0017 0.0014
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0045 0.0014 0.0025
Brugia malayi G protein-coupled receptor 0.0329 0.0202 0.051
Loa Loa (eye worm) orotate phosphoribosyltransferase 0.0091 0.0044 0.0098
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0009 0.0031
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.2719 0.1784 0.1778
Echinococcus multilocularis microtubule associated protein 2 0.0931 0.0601 0.1148
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0427 0.0267 0.1477
Loa Loa (eye worm) hypothetical protein 0.0328 0.0201 0.0474
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0045 0.0014 0.0027
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0329 0.0202 0.051
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0009 0.0017
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.2555 0.1676 0.4293
Echinococcus multilocularis leukotriene A 4 hydrolase 0.0253 0.0152 0.0288
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0045 0.0014 0.0027
Echinococcus multilocularis purine nucleoside phosphorylase 0.0045 0.0013 0.0024
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0061 0.0024 0.0044
Onchocerca volvulus 0.0054 0.002 0.006
Plasmodium falciparum plasmepsin VI 0.0219 0.0129 0.0121
Mycobacterium leprae conserved hypothetical protein 0.0069 0.0029 0.002
Plasmodium vivax aspartyl protease, putative 0.0058 0.0022 0.0013
Brugia malayi Peptidase family M13 containing protein 0.2555 0.1676 0.4293
Trypanosoma cruzi DNA/RNA non-specific endonuclease protein-like, putative 0.0047 0.0015 0.0066
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.012 0.0063 0.132
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0056 0.0021 0.0019
Loa Loa (eye worm) TYRA-2 protein 0.0329 0.0202 0.0476
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.0074 0.0033 0.0165
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0018 0.008
Echinococcus granulosus g-protein coupled receptor 0.0329 0.0202 0.0385
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0424 0.0265 0.0626
Echinococcus granulosus tyrosine protein kinase Fyn 0.0042 0.0011 0.002
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0514 0.0324 0.0618
Echinococcus granulosus folylpolyglutamate synthase, mitochondrial 0.0153 0.0085 0.0162
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0425 0.0265 0.0803
Loa Loa (eye worm) phosphotyrosine protein phosphatase 0.0218 0.0128 0.0299
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0009 0.0017
Trichomonas vaginalis CMGC family protein kinase 0.0047 0.0015 0.0065
Brugia malayi putative neuropeptide receptor 0.0329 0.0202 0.051
Mycobacterium ulcerans epimerase 0.0069 0.0029 0.0027
Mycobacterium tuberculosis Hypoxanthine-guanine phosphoribosyltransferase Hpt (HGPRT) (HGPRTase) (hypoxanthine phosphoribosyltransferase) (imp pyrophosphor 0.0297 0.0181 0.0361
Loa Loa (eye worm) RecQ helicase 0.0072 0.0032 0.0069
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0005 0.0001
Echinococcus granulosus survival motor neuron protein 1 0.0333 0.0204 0.0389
Plasmodium falciparum plasmepsin II 0.0219 0.0129 0.0121
Brugia malayi regulator of G-protein signaling rgs-7 0.0031 0.0005 0.0004
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0163 0.0092 0.0183
Leishmania major squalene synthase, putative 0.0264 0.0159 0.0888
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0074 0.0033 0.0071
Brugia malayi hypothetical protein 0.0329 0.0202 0.051
Echinococcus multilocularis tyrosine protein kinase Blk 0.0038 0.0009 0.0015
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0038 0.0009 0.0015
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0045 0.0014 0.0025
Brugia malayi Angiotensin-converting enzyme family protein 0.4183 0.2754 0.706
Onchocerca volvulus 0.0383 0.0237 0.0718
Echinococcus multilocularis neuropeptide receptor 0.0329 0.0202 0.0385
Echinococcus granulosus chromobox protein 1 0.0084 0.0039 0.0073
Trypanosoma cruzi hypothetical protein, conserved 0.012 0.0063 0.0336
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0049 0.0017 0.003
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0045 0.0014 0.0025
Schistosoma mansoni hypothetical protein 0.0667 0.0425 0.2217
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0056 0.0021 0.0039
Brugia malayi peptidase family M13 containing protein 0.0622 0.0396 0.1008
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0015 0.0064
Brugia malayi hypothetical protein 0.0329 0.0202 0.051
Onchocerca volvulus 0.0186 0.0107 0.0323
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.012 0.0063 0.0335
Brugia malayi Glycosyl hydrolases family 31 protein 0.0094 0.0046 0.011
Echinococcus granulosus neuropeptides capa receptor 0.0329 0.0202 0.0385
Echinococcus granulosus rhodopsin orphan GPCR 0.0329 0.0202 0.0385
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0073 0.0032 0.0145
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0045 0.0014 0.0025
Brugia malayi orotate phosphoribosyltransferase family protein 0.0091 0.0044 0.0105
Echinococcus multilocularis nAChR subunit 0.0045 0.0014 0.0025
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.0074 0.0033 0.0061
Mycobacterium ulcerans peptide deformylase 0.0201 0.0117 0.0114
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0156 0.0087 0.0165
Echinococcus multilocularis purine nucleoside phosphorylase 0.0045 0.0013 0.0024
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0009 0.0047
Onchocerca volvulus 0.0033 0.0006 0.0017
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0047 0.0015 0.0064
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0009 0.0047
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.4183 0.2754 0.6585
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0329 0.0202 0.104
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0622 0.0396 0.2062
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0329 0.0202 0.0385
Schistosoma mansoni glutamate receptor NMDA 0.0234 0.0139 0.0706
Schistosoma mansoni 6-phosphofructokinase 0.0064 0.0026 0.0114
Echinococcus granulosus 6 phosphofructokinase 0.0064 0.0026 0.0048
Trypanosoma brucei endonuclease G, putative 0.0047 0.0015 0.0082
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0514 0.0324 0.0618
Echinococcus multilocularis thyroid hormone receptor alpha 0.0161 0.0091 0.0172
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0149 0.0083 0.0156
Schistosoma mansoni hypothetical protein 0.0072 0.0032 0.0143
Echinococcus multilocularis voltage dependent calcium channel subunit 0.0104 0.0053 0.0099
Onchocerca volvulus 0.012 0.0063 0.0191
Echinococcus granulosus receptor type guanylyl cyclase 0.0425 0.0265 0.0506
Onchocerca volvulus 0.0329 0.0202 0.0611
Echinococcus granulosus expressed protein 0.0609 0.0387 0.0739
Brugia malayi hypothetical protein 0.0383 0.0237 0.0601
Trypanosoma cruzi Peptide deformylase 2, putative 0.0077 0.0035 0.0176
Plasmodium vivax aspartyl proteinase, putative 0.0058 0.0022 0.0013
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0329 0.0202 0.0385
Echinococcus multilocularis glutamate cysteine ligase, catalytic subunit 0.006 0.0023 0.0043
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0045 0.0014 0.0025
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0329 0.0202 0.0385
Treponema pallidum adenine phosphoribosyltransferase 0.0091 0.0044 0.0023
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0078 0.0035 0.0066
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0005 0.0001
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0424 0.0265 0.0671
Loa Loa (eye worm) hypothetical protein 0.0066 0.0027 0.0058
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0427 0.0267 0.138
Trypanosoma brucei folylpolyglutamate synthase, putative 0.0153 0.0085 0.0477
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0045 0.0014 0.0025
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0307 0.0187 0.1032
Trypanosoma cruzi glutamine synthetase, putative 0.0519 0.0327 0.1821
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0329 0.0202 0.0385
Onchocerca volvulus 0.0329 0.0202 0.0611
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0103 0.0052 0.0031
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0045 0.0014 0.0027
Trypanosoma cruzi orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative 0.0091 0.0044 0.0229
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0733 0.0469 0.0456
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Brugia malayi hypothetical protein 0.0329 0.0202 0.051
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0622 0.0396 0.2062
Mycobacterium tuberculosis Conserved protein 0.0091 0.0044 0.0088
Loa Loa (eye worm) 6-phosphofructokinase 0.0064 0.0026 0.0055
Echinococcus multilocularis regulator of G protein signaling 7 0.0031 0.0005 0.0007
Trichomonas vaginalis purine nucleoside phosphorylase I, putative 0.0056 0.0021 0.0099
Echinococcus multilocularis rhodopsin orphan GPCR 0.0329 0.0202 0.0385
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0009 0.0031
Echinococcus granulosus glutamate receptor 2 0.056 0.0355 0.0677
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0009 0.0047
Echinococcus multilocularis geminin 0.0215 0.0126 0.024
Mycobacterium leprae Probable hypoxanthine-guanine phosphoribosyltransferase Hpt (HGPRT) (HGPRTase) (hypoxanthine phosphoribosyltransferase) (IMP pho 0.0297 0.0181 0.0172
Loa Loa (eye worm) peptidase family M1 containing protein 0.1325 0.0862 0.2055
Echinococcus granulosus tm gpcr rhodopsin 0.0329 0.0202 0.0385
Leishmania major polypeptide deformylase-like protein, putative 0.0077 0.0035 0.0192
Plasmodium falciparum plasmepsin X 0.0058 0.0022 0.0014
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0156 0.0087 0.0487
Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferase 0.0388 0.0241 0.1245
Echinococcus granulosus serotonin receptor 0.0329 0.0202 0.0385
Trypanosoma brucei solanesyl-diphosphate synthase, putative 0.0701 0.0448 0.251
Echinococcus granulosus neuropeptide receptor 0.0329 0.0202 0.0385
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0054 0.0019 0.0035
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0186 0.0107 0.0098
Echinococcus multilocularis bloom syndrome protein 0.0072 0.0032 0.0059
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0045 0.0014 0.0027
Brugia malayi cytoplasmic intermediate filament protein 0.0054 0.002 0.0042
Plasmodium falciparum plasmepsin VIII, putative 0.0058 0.0022 0.0014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0329 0.0202 0.104
Echinococcus granulosus hypoxanthine guanine phosphoribosyltransferase 0.0388 0.0241 0.0459
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0056 0.0021 0.0101
Brugia malayi Intermediate filament tail domain containing protein 0.0101 0.0051 0.0122
Echinococcus multilocularis metabotropic glutamate receptor 2 0.1689 0.1103 0.2109
Giardia lamblia Glutamate-cysteine ligase 0.006 0.0023 0.013
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.056 0.0355 0.0677
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0219 0.0129 0.0245
Schistosoma mansoni nAChR subunit 0.0045 0.0014 0.0048
Mycobacterium ulcerans phosphoribosylamine--glycine ligase 0.0046 0.0014 0.0012
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.012 0.0063 0.0119
Entamoeba histolytica recQ family helicase, putative 0.0044 0.0013 0.0192
Loa Loa (eye worm) hypothetical protein 0.1888 0.1234 0.2947
Echinococcus granulosus metabotropic glutamate receptor 2 0.1689 0.1103 0.2109
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0329 0.0202 0.104
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Echinococcus granulosus biogenic amine 5HT receptor 0.0329 0.0202 0.0385
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Toxoplasma gondii MRP family domain-containing protein 0.0081 0.0038 0.0029
Echinococcus multilocularis neuropeptide FF receptor 2 0.0329 0.0202 0.0385
Toxoplasma gondii aminopeptidase N protein 0.0186 0.0107 0.0099
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0427 0.0267 0.063
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0045 0.0014 0.0048
Onchocerca volvulus 0.0045 0.0014 0.0042
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0427 0.0267 0.5905
Brugia malayi Polyprenyl synthetase family protein 0.2719 0.1784 0.4571
Loa Loa (eye worm) adenine phosphoribosyltransferase 0.0091 0.0044 0.0098
Plasmodium falciparum thioredoxin reductase 0.0056 0.0021 0.0013
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0069 0.0029 0.0027
Toxoplasma gondii NADPH-glutathione reductase 0.0056 0.0021 0.0013
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.012 0.0063 0.0143
Onchocerca volvulus 0.0329 0.0202 0.0611
Wolbachia endosymbiont of Brugia malayi glutamine synthetase 0.0732 0.0469 0.0455
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0054 0.0019 0.0035
Mycobacterium ulcerans oxidoreductase 0.0078 0.0035 0.0033
Loa Loa (eye worm) hypothetical protein 0.0212 0.0124 0.0289
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0042 0.0011 0.002
Schistosoma mansoni serine-rich repeat protein 0.0054 0.0019 0.0078
Brugia malayi follicle stimulating hormone receptor 0.1073 0.0695 0.1775
Loa Loa (eye worm) hypothetical protein 0.0069 0.0029 0.0062
Echinococcus multilocularis voltage dependent calcium channel subunit 0.0228 0.0135 0.0257
Echinococcus granulosus endothelin converting enzyme 1 0.2555 0.1676 0.3206
Echinococcus granulosus voltage dependent calcium channel subunit 0.0228 0.0135 0.0257
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0234 0.0139 0.0264
Mycobacterium ulcerans polyprenyl synthetase IdsB 0.0733 0.0469 0.0467
Echinococcus multilocularis Squalene phytoene synthase 0.0082 0.0038 0.0072
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0219 0.0129 0.0301
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0056 0.0021 0.0019
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0329 0.0202 0.104
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0329 0.0202 0.0476
Brugia malayi protein-tyrosine kinase 0.0038 0.0009 0.0014
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0622 0.0396 0.2062
Echinococcus multilocularis neuropeptide receptor A26 0.0603 0.0383 0.0732
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0056 0.0021 0.0012
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0056 0.0021 0.0101
Echinococcus multilocularis orexin receptor type 2 0.0329 0.0202 0.0385
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0242 0.0144 0.0288
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0078 0.0035 0.0066
Toxoplasma gondii hypothetical protein 0.012 0.0063 0.0055
Plasmodium falciparum plasmepsin IV 0.0219 0.0129 0.0121
Trypanosoma cruzi protein farnesyltransferase, putative 0.0074 0.0033 0.0167
Loa Loa (eye worm) hypothetical protein 0.2324 0.1523 0.3637
Loa Loa (eye worm) hypothetical protein 0.0329 0.0202 0.0476
Loa Loa (eye worm) hypothetical protein 0.0681 0.0435 0.1033
Loa Loa (eye worm) RGC/RGC protein kinase 0.0425 0.0265 0.0628
Echinococcus multilocularis rhodopsin orphan GPCR 0.0329 0.0202 0.0385
Brugia malayi hypothetical protein 0.0383 0.0237 0.0601
Schistosoma mansoni nAChR subunit 0.0045 0.0014 0.0048
Entamoeba histolytica glutamine synthetase, putative 0.0245 0.0146 0.3188
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0045 0.0014 0.0025
Onchocerca volvulus Adenine phosphoribosyltransferase homolog 0.0091 0.0044 0.0133
Loa Loa (eye worm) peptidase family M13 containing protein 0.1888 0.1234 0.2947
Brugia malayi Tachykinin-like peptides receptor 99D 0.0329 0.0202 0.051
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0005 0.0006

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) = 3.4 uM Inhibition of collagen-induced platelet aggregation in human platelet-rich plasma. ChEMBL. 8289199
EC50 (functional) = 3.4 uM Inhibition of collagen-induced platelet aggregation in human platelet-rich plasma. ChEMBL. 8289199
IC50 (binding) = 0.005 uM Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets. ChEMBL. 8289199
IC50 (binding) = 0.005 uM Inhibition test of thromboxane A2 synthetase in human gel-filtered platelets. ChEMBL. 8289199
IC50 (binding) = 0.081 uM Displacement of the high affinity radiolabeled ligand [3H]- SQ-29,548 from the PGH-2/TXA-2 receptor in human gel-filtered platelets. ChEMBL. 8289199
IC50 (binding) = 0.081 uM Displacement of the high affinity radiolabeled ligand [3H]- SQ-29,548 from the PGH-2/TXA-2 receptor in human gel-filtered platelets. ChEMBL. 8289199

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 8289199

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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