Detailed information for compound 309445

Basic information

Technical information
  • TDR Targets ID: 309445
  • Name: 2-[2-[2-(4-methyl-3-oxo-1,4-benzoxazin-2-yl)e thoxy]phenyl]acetic acid
  • MW: 341.358 | Formula: C19H19NO5
  • H donors: 1 H acceptors: 3 LogP: 2.58 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)Cc1ccccc1OCCC1Oc2ccccc2N(C1=O)C
  • InChi: 1S/C19H19NO5/c1-20-14-7-3-5-9-16(14)25-17(19(20)23)10-11-24-15-8-4-2-6-13(15)12-18(21)22/h2-9,17H,10-12H2,1H3,(H,21,22)
  • InChiKey: WQWSVUZCDSOQKC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-[2-[2-(4-methyl-3-oxo-1,4-benzoxazin-2-yl)ethoxy]phenyl]ethanoic acid
  • 2-[2-[2-(3-keto-4-methyl-1,4-benzoxazin-2-yl)ethoxy]phenyl]acetic acid

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens peroxisome proliferator-activated receptor gamma Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus granulosus ecdysone induced protein 78C peroxisome proliferator-activated receptor gamma 477 aa 447 aa 28.2 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus neuropeptide Y receptor 0.0102 0.1225 0.2999
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.001 0.0085 0.938
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Entamoeba histolytica hypothetical protein 0.0036 0.0411 0.5826
Mycobacterium tuberculosis Probable dehydrogenase 0.0022 0.0232 0.2833
Mycobacterium tuberculosis Probable alpha-glucosidase AglA (maltase) (glucoinvertase) (glucosidosucrase) (maltase-glucoamylase) (lysosomal alpha-glucosidas 0.0007 0.0046 0.0501
Echinococcus granulosus rhodopsin orphan GPCR 0.0102 0.1225 0.2999
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0011 0.0096 0.0151
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0102 0.1225 0.1225
Brugia malayi Tachykinin-like peptides receptor 99D 0.0102 0.1225 0.1919
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0005 0.0022 0.0034
Trypanosoma brucei DNA polymerase IV, putative 0.0004 0.002 0.007
Brugia malayi bZIP transcription factor family protein 0.0007 0.0057 0.0088
Entamoeba histolytica hypothetical protein 0.0036 0.0411 0.5826
Mycobacterium tuberculosis Trehalose synthase TreS 0.0007 0.0046 0.0501
Schistosoma mansoni netrin receptor unc5 0.0011 0.01 0.0279
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0008 0.0064 0.0156
Brugia malayi nuclear receptor NHR-88 0.0031 0.0347 0.0542
Loa Loa (eye worm) ACC-1 protein 0.0008 0.0064 0.01
Echinococcus granulosus raf serine:threonine protein kinase 0.0007 0.0049 0.0119
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0003 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0004 0.0011 0.0018
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0065 0.0773 0.1892
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0031 0.0347 0.0849
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0003 0.0008 0.0021
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.001 0.0085 0.0134
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0034 0.0392 0.0392
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0065 0.0773 0.0773
Trypanosoma brucei DNA polymerase kappa, putative 0.0004 0.002 0.007
Loa Loa (eye worm) hypothetical protein 0.0081 0.0966 0.1515
Mycobacterium ulcerans phytoene synthase, CrtB 0.0068 0.0803 1
Loa Loa (eye worm) hypothetical protein 0.0068 0.0803 0.1259
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0003 0.0002 0.0002
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0005 0.0022 0.0022
Schistosoma mansoni nAChR subunit 0.0008 0.0064 0.0179
Echinococcus multilocularis neuropeptides capa receptor 0.0102 0.1225 0.1225
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0022 0.0232 0.2833
Echinococcus granulosus glucan 14 alpha branching enzyme 1 0.0026 0.0292 0.0716
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0005 0.0022 0.0032
Echinococcus granulosus fibropellin Ia 0.0018 0.0185 0.0453
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0008 0.0064 0.0064
Loa Loa (eye worm) nuclear hormone receptor 0.0031 0.0347 0.0543
Brugia malayi GnHR receptor homolog 0.0102 0.1225 0.1919
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0003 0.0002 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0007 0.0051 0.0143
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0008 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0003 0.0002 0.0003
Echinococcus granulosus protein jagged 1 0.0018 0.0185 0.0453
Onchocerca volvulus 0.0005 0.0022 0.0055
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0003 0.0002 0.0001
Brugia malayi Animal haem peroxidase family protein 0.0069 0.0814 0.1274
Onchocerca volvulus 0.0018 0.0185 0.0693
Loa Loa (eye worm) hypothetical protein 0.0022 0.0238 0.0373
Echinococcus granulosus death domain containing protein 0.0011 0.01 0.0244
Trypanosoma brucei squalene monooxygenase, putative 0.0197 0.2405 0.9075
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0003 0.0006 0.0047
Brugia malayi Aldehyde dehydrogenase protein 4 0.0003 0.0008 0.001
Toxoplasma gondii HEAT repeat-containing protein 0.0007 0.0052 0.052
Echinococcus granulosus cyclic AMP responsive element binding protein 0.0007 0.0057 0.014
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0005 0.0022 0.0075
Schistosoma mansoni hypothetical protein 0.001 0.0092 0.0257
Echinococcus multilocularis rhodopsin orphan GPCR 0.0102 0.1225 0.1225
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0008 0.0064 0.0156
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Schistosoma mansoni ran 0.0005 0.0029 0.0082
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0012 0.012 0.0337
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0005 0.0022 0.0032
Loa Loa (eye worm) hypothetical protein 0.0061 0.0714 0.112
Schistosoma mansoni carbonic anhydrase-related 0.0081 0.0966 0.2708
Echinococcus multilocularis netrin receptor unc 5 0.0011 0.01 0.01
Schistosoma mansoni kinesin eg-5 0.001 0.0091 0.0255
Loa Loa (eye worm) hypothetical protein 0.0018 0.0185 0.029
Echinococcus multilocularis rhodopsin orphan GPCR 0.0102 0.1225 0.1225
Schistosoma mansoni nAChR subunit 0.0008 0.0064 0.0179
Loa Loa (eye worm) hypothetical protein 0.0005 0.0022 0.0034
Brugia malayi RhoGEF domain containing protein 0.0007 0.0049 0.0075
Echinococcus multilocularis g-protein coupled receptor 0.0102 0.1225 0.1225
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0005 0.0022 0.0022
Schistosoma mansoni neuropeptide F-like receptor 0.0102 0.1225 0.3432
Echinococcus granulosus neuropeptide FF receptor 2 0.0102 0.1225 0.2999
Echinococcus granulosus somatostatin receptor 0.0102 0.1225 0.2999
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0005 0.0029 0.0285
Schistosoma mansoni RAR-like nuclear receptor 0.0065 0.0773 0.2166
Echinococcus multilocularis Niemann Pick C1 protein 0.0035 0.04 0.04
Loa Loa (eye worm) hypothetical protein 0.0038 0.0432 0.0677
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0008 0.0064 0.0098
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0008 0.0064 0.0179
Toxoplasma gondii 1,4-alpha-glucan-branching enzyme 0.0026 0.0292 0.301
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0015 0.0157 0.0439
Echinococcus granulosus expressed conserved protein 0.0023 0.0251 0.0615
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0102 0.1225 0.1225
Echinococcus multilocularis inhibitor of apoptosis protein 0.0017 0.0176 0.0176
Schistosoma mansoni starch branching enzyme II 0.0026 0.0292 0.0819
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0024 0.0261 0.0639
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0004 0.0019 0.0028
Leishmania major aldehyde dehydrogenase, putative 0.0003 0.0008 0.0021
Brugia malayi hypothetical protein 0.0102 0.1225 0.1919
Loa Loa (eye worm) hypothetical protein 0.0008 0.0064 0.01
Trichomonas vaginalis alpha-amylase, putative 0.0059 0.07 1
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0011 0.01 0.0244
Onchocerca volvulus Bile acid receptor homolog 0.0065 0.0773 0.2985
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0065 0.0773 0.2166
Echinococcus multilocularis protein kinase c eta type 0.0007 0.0049 0.0049
Onchocerca volvulus 0.0008 0.0064 0.022
Echinococcus granulosus 7tm_1 domain containing protein 0.0102 0.1225 0.2999
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0005 0.0022 0.0061
Echinococcus multilocularis para nitrobenzyl esterase 0.0012 0.012 0.012
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0005 0.0022 0.0034
Loa Loa (eye worm) hypothetical protein 0.0012 0.012 0.0189
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0005 0.0022 0.0032
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0005 0.0029 0.0029
Echinococcus multilocularis thioredoxin glutathione reductase 0.001 0.0084 0.0084
Mycobacterium tuberculosis Probable methylmalonate-semialdehyde dehydrogenase MmsA (methylmalonic acid semialdehyde dehydrogenase) (MMSDH) 0.0003 0.0008 0.0014
Trichomonas vaginalis rap1 and, putative 0.0038 0.0439 0.6256
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0102 0.1225 0.3432
Loa Loa (eye worm) hypothetical protein 0.0004 0.0019 0.0029
Trichomonas vaginalis DNA polymerase eta, putative 0.0004 0.002 0.0265
Entamoeba histolytica hypothetical protein 0.0036 0.0411 0.5826
Brugia malayi nuclear hormone receptor family member odr-7 0.0031 0.0347 0.0542
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0003 0.0002 0.0005
Schistosoma mansoni fos transcription factor-related 0.0007 0.0057 0.016
Trypanosoma brucei importin beta-1 subunit, putative 0.0007 0.0052 0.0189
Brugia malayi ecdysone receptor 0.0031 0.0347 0.0542
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0005 0.0022 0.0061
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0003 0.0008 0.0021
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0008 0.0064 0.0156
Loa Loa (eye worm) hypothetical protein 0.0065 0.0773 0.1212
Echinococcus granulosus allatostatin A receptor 0.0102 0.1225 0.2999
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0003 0.0002 0.0005
Echinococcus granulosus Nuclear hormone receptor HR96 0.0031 0.0347 0.0849
Loa Loa (eye worm) hypothetical protein 0.0017 0.0176 0.0276
Schistosoma mansoni terminal deoxycytidyl transferase 0.0004 0.002 0.0057
Echinococcus granulosus neuropeptides capa receptor 0.0102 0.1225 0.2999
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0065 0.0773 0.1892
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, GabD1 0.0003 0.0008 0.0014
Trichomonas vaginalis alpha-amylase, putative 0.0007 0.0046 0.0636
Echinococcus granulosus trehalose 6 phosphate hydrolase 0.0007 0.0046 0.0114
Toxoplasma gondii exonuclease III APE 0.001 0.0085 0.0866
Brugia malayi Ras-related protein R-Ras2 0.0038 0.0439 0.0686
Schistosoma mansoni serine/threonine protein kinase 0.0007 0.0049 0.0136
Echinococcus multilocularis neurogenic locus protein delta 0.0018 0.0185 0.0185
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0024 0.0262 0.3206
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0102 0.1225 0.3432
Onchocerca volvulus 0.0005 0.0022 0.0055
Echinococcus multilocularis rhodopsin orphan GPCR 0.0102 0.1225 0.1225
Onchocerca volvulus Slit protein homolog 0.0018 0.0185 0.0693
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0046 0.0636
Echinococcus granulosus delta-like protein 1 0.0018 0.0185 0.0453
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0003 0.0006 0.051
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0022 0.0232 0.8832
Loa Loa (eye worm) hypothetical protein 0.0065 0.0773 0.1212
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0003 0.0008 0.0021
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.001 0.0085 0.0992
Echinococcus granulosus Diacylglycerol kinase theta 0.0007 0.0049 0.0119
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0347 0.0971
Schistosoma mansoni nAChR subunit 0.0008 0.0064 0.0179
Echinococcus granulosus tm gpcr rhodopsin 0.0102 0.1225 0.2999
Loa Loa (eye worm) hypothetical protein 0.0034 0.0392 0.0615
Schistosoma mansoni alpha-amylase 0.0007 0.0046 0.013
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0025 0.0274 0.0769
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0008 0.0064 0.0098
Trichomonas vaginalis amylase, putative 0.0059 0.07 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0065 0.0773 0.1212
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.001 0.0085 0.0209
Brugia malayi Animal haem peroxidase family protein 0.0069 0.0814 0.1274
Onchocerca volvulus 0.0026 0.0286 0.1086
Echinococcus multilocularis cAMP responsive element binding protein 3 0.0007 0.0057 0.0057
Echinococcus multilocularis trehalose 6 phosphate hydrolase 0.0007 0.0046 0.0046
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0102 0.1225 0.4748
Brugia malayi Cation transporter family protein 0.0008 0.0064 0.0098
Loa Loa (eye worm) hypothetical protein 0.0031 0.0347 0.0543
Loa Loa (eye worm) hypothetical protein 0.0069 0.0814 0.1276
Trichomonas vaginalis alpha-amylase, putative 0.0007 0.0046 0.0636
Echinococcus multilocularis neuropeptide receptor A26 0.0333 0.4083 0.4083
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0005 0.0022 0.0022
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0005 0.0022 0.0034
Schistosoma mansoni hypothetical protein 0.0011 0.01 0.0279
Brugia malayi Calcium binding EGF domain containing protein 0.0018 0.0185 0.0288
Onchocerca volvulus 0.0004 0.0011 0.0014
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0022 0.0232 0.2833
Mycobacterium ulcerans glycosidase 0.0007 0.0046 0.0501
Echinococcus granulosus inhibitor of apoptosis protein 0.0017 0.0176 0.0431
Loa Loa (eye worm) hypothetical protein 0.0005 0.0022 0.0034
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Schistosoma mansoni hypothetical protein 0.0018 0.0185 0.0519
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0102 0.1225 0.3432
Echinococcus granulosus kinesin family 1 0.0078 0.0928 0.2272
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0004 0.0015 0.0036
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0003 0.0002 0.0005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0003 0.0006 0.0017
Echinococcus multilocularis Smad4 0.0004 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0003 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0021 0.0225 0.0225
Mycobacterium ulcerans carboxylesterase, LipT 0.0012 0.012 0.1429
Mycobacterium ulcerans gamma-glutamyl phosphate reductase 0.0003 0.0008 0.0014
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0004 0.0019 0.0028
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Onchocerca volvulus Neurogenic locus notch homolog 0.0018 0.0186 0.0697
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0004 0.0019 0.0028
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0008 0.0064 0.0179
Onchocerca volvulus 0.0102 0.1225 0.4748
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0003 0.0008 0.0021
Echinococcus multilocularis glycine receptor subunit beta 0.0008 0.0064 0.0064
Echinococcus granulosus cpg binding protein 0.0008 0.0061 0.015
Brugia malayi hypothetical protein 0.0004 0.0011 0.0016
Schistosoma mansoni alpha-amylase 0.0007 0.0046 0.013
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0102 0.1225 0.1225
Brugia malayi bZIP transcription factor family protein 0.0007 0.0057 0.0088
Onchocerca volvulus 0.0007 0.0057 0.0193
Loa Loa (eye worm) hypothetical protein 0.0065 0.0773 0.1212
Onchocerca volvulus 0.0026 0.0286 0.1086
Echinococcus multilocularis unc 13 (munc13) 0.0007 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0004 0.0011 0.0018
Loa Loa (eye worm) hypothetical protein 0.0065 0.0773 0.1212
Loa Loa (eye worm) hypothetical protein 0.0069 0.0814 0.1276
Echinococcus granulosus protein jagged 2 0.0018 0.0185 0.0453
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.072 0.745
Echinococcus multilocularis nAChR subunit 0.0004 0.0019 0.0019
Onchocerca volvulus 0.0102 0.1225 0.4748
Mycobacterium ulcerans piperideine-6-carboxilic acid dehydrogenase Pcd 0.0003 0.0008 0.0014
Schistosoma mansoni protein tyrosine phosphatase 0.0005 0.0022 0.0061
Echinococcus granulosus nuclear factor of activated T cells 5 0.0055 0.065 0.1592
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0012 0.012 0.0294
Loa Loa (eye worm) hypothetical protein 0.0011 0.01 0.0156
Echinococcus granulosus para nitrobenzyl esterase 0.0012 0.012 0.0294
Echinococcus multilocularis neuropeptides capa receptor 0.0102 0.1225 0.1225
Loa Loa (eye worm) hypothetical protein 0.0069 0.0814 0.1276
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, PutA_2 0.0003 0.0008 0.0014
Brugia malayi Protein kinase c protein 2 0.0007 0.0051 0.0078
Brugia malayi hypothetical protein 0.0102 0.1225 0.1919
Echinococcus granulosus alpha 1A adrenergic receptor 0.0102 0.1225 0.2999
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0008 0.0064 0.0098
Echinococcus granulosus alpha glucosidase 0.0007 0.0046 0.0114
Loa Loa (eye worm) hypothetical protein 0.0004 0.0011 0.0018
Leishmania major protein-tyrosine phosphatase 1-like protein 0.0005 0.0022 0.0075
Brugia malayi Carboxylesterase family protein 0.0074 0.0879 0.1376
Loa Loa (eye worm) hypothetical protein 0.0008 0.0064 0.01
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Loa Loa (eye worm) hypothetical protein 0.0004 0.002 0.0032
Onchocerca volvulus 0.0005 0.0022 0.0055
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0005 0.0029 0.0104
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0005 0.0022 0.0022
Entamoeba histolytica hypothetical protein 0.0036 0.0411 0.5826
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0008 0.0064 0.0098
Leishmania major aldehyde dehydrogenase, putative 0.0003 0.0008 0.0021
Onchocerca volvulus 0.0102 0.1225 0.4748
Echinococcus multilocularis ecdysone induced protein 78C 0.0065 0.0773 0.0773
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0005 0.0029 0.3085
Echinococcus granulosus Ankyrin 0.0011 0.0101 0.0247
Onchocerca volvulus 0.0008 0.0064 0.022
Schistosoma mansoni hypothetical protein 0.0018 0.0185 0.0519
Onchocerca volvulus Putative cubilin 0.0018 0.0185 0.0693
Loa Loa (eye worm) hypothetical protein 0.0018 0.0185 0.029
Brugia malayi Nuclear hormone receptor E75 0.0031 0.0347 0.0542
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Brugia malayi G protein-coupled receptor F59B2.13 0.0102 0.1225 0.1919
Schistosoma mansoni alpha-amylase 0.0007 0.0046 0.013
Trypanosoma cruzi squalene monooxygenase, putative 0.0197 0.2405 0.9075
Loa Loa (eye worm) hypothetical protein 0.0011 0.0096 0.0151
Trichomonas vaginalis rheb, putative 0.0038 0.0439 0.6256
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0005 0.0022 0.0032
Brugia malayi ORL1-like opioid receptor 0.0102 0.1225 0.1919
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.072 0.8964
Loa Loa (eye worm) hypothetical protein 0.0018 0.0185 0.029
Loa Loa (eye worm) hypothetical protein 0.0004 0.0019 0.0029
Loa Loa (eye worm) G-protein coupled receptor 0.0102 0.1225 0.192
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.001 0.0085 0.0866
Echinococcus granulosus sex peptide receptor 0.0102 0.1225 0.2999
Loa Loa (eye worm) neuropeptide F receptor 0.0102 0.1225 0.192
Echinococcus multilocularis protein jagged 1 0.0018 0.0185 0.0185
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0004 0.002 0.0175
Trichomonas vaginalis alpha-amylase, putative 0.0007 0.0046 0.0636
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0004 0.0019 0.0053
Loa Loa (eye worm) MH2 domain-containing protein 0.0059 0.0691 0.1084
Brugia malayi Ras association domain family 1 isoform A 0.0007 0.0049 0.0075
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0102 0.1225 0.2999
Loa Loa (eye worm) hypothetical protein 0.0003 0.0008 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0065 0.0773 0.121
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0102 0.1225 0.3432
Schistosoma mansoni nAChR subunit 0.0004 0.0011 0.0031
Plasmodium falciparum kinesin-5 0.001 0.0091 0.0923
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0054 0.0634 0.0994
Echinococcus granulosus neurogenic locus notch protein 4 0.0018 0.0185 0.0453
Echinococcus granulosus carbonic anhydrase 0.0081 0.0966 0.2366
Loa Loa (eye worm) hypothetical protein 0.0069 0.0814 0.1276
Trichomonas vaginalis mercuric reductase, putative 0.0003 0.0006 0.0065
Loa Loa (eye worm) GABA receptor subunit 0.0004 0.0019 0.0029
Onchocerca volvulus 0.0004 0.0011 0.0014
Echinococcus multilocularis dnaJ subfamily B 0.0104 0.1247 0.1247
Trichomonas vaginalis amylase, putative 0.0059 0.07 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0065 0.0773 0.121
Loa Loa (eye worm) hypothetical protein 0.0008 0.0064 0.01
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0003 0.0008 0.0021
Brugia malayi Protein kinase domain containing protein 0.0007 0.0051 0.0078
Brugia malayi Calcium binding EGF domain containing protein 0.0018 0.0185 0.0288
Loa Loa (eye worm) hypothetical protein 0.0004 0.0011 0.0018
Echinococcus multilocularis slit 2 protein 0.0018 0.0185 0.0185
Loa Loa (eye worm) hypothetical protein 0.0031 0.0347 0.0543
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0024 0.0261 0.0731
Schistosoma mansoni hypothetical protein 0.0081 0.0966 0.2708
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0178 0.2164 0.3393
Mycobacterium tuberculosis Maltooligosyltrehalose synthase TreY 0.0007 0.0046 0.0501
Onchocerca volvulus 0.0012 0.012 0.044
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0004 0.0011 0.0027
Echinococcus multilocularis neuroligin 0.0012 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0012 0.012 0.0189
Echinococcus multilocularis thyroid hormone receptor alpha 0.0065 0.0773 0.0773
Echinococcus multilocularis G-protein coupled receptor, putative 0.0102 0.1225 0.1225
Trypanosoma brucei DNA polymerase kappa, putative 0.0003 0.0004 0.0006
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0102 0.1225 0.1919
Schistosoma mansoni retinoic acid receptor RXR 0.0065 0.0773 0.2166
Brugia malayi Uncoordinated protein 44 0.0011 0.01 0.0154
Loa Loa (eye worm) hypothetical protein 0.0007 0.0049 0.0076
Loa Loa (eye worm) hypothetical protein 0.0008 0.0064 0.01
Loa Loa (eye worm) transcription factor SMAD2 0.0059 0.0691 0.1084
Mycobacterium ulcerans glycogen branching protein 0.0026 0.0292 0.3588
Brugia malayi nuclear receptor RXR 0.0031 0.0347 0.0542
Loa Loa (eye worm) hypothetical protein 0.0031 0.0347 0.0543
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0005 0.0022 0.0032
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0022 0.0232 0.2833
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0102 0.1225 0.1919
Trichomonas vaginalis succinate semialdehyde dehydrogenase, putative 0.0003 0.0008 0.0081
Brugia malayi EGF-like domain containing protein 0.0018 0.0185 0.0288
Echinococcus multilocularis acetylcholinesterase 0.0074 0.0879 0.0879
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0005 0.0022 0.0053
Echinococcus multilocularis expressed conserved protein 0.0023 0.0251 0.0251
Toxoplasma gondii Alpha-amylase AMY3, putative 0.0007 0.0046 0.0461
Loa Loa (eye worm) Notch2 0.0018 0.0185 0.029
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0007 0.0049 0.0136
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0008 0.0064 0.0098
Brugia malayi nuclear hormone receptor 0.0065 0.0773 0.121
Loa Loa (eye worm) hypothetical protein 0.0018 0.0185 0.029
Entamoeba histolytica hypothetical protein 0.0007 0.0049 0.0593
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0005 0.0022 0.0061
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0005 0.0022 0.0075
Brugia malayi RhoGAP domain containing protein 0.0007 0.0049 0.0075
Loa Loa (eye worm) hypothetical protein 0.0004 0.0011 0.0018
Schistosoma mansoni hypothetical protein 0.001 0.0092 0.0257
Echinococcus multilocularis myotubularin protein 13 0.0008 0.0071 0.0071
Schistosoma mansoni protein-tyrosine phosphatase n9 0.0005 0.0022 0.0061
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0012 0.012 0.012
Echinococcus multilocularis somatostatin receptor 0.0102 0.1225 0.1225
Echinococcus multilocularis notch 0.0018 0.0185 0.0185
Brugia malayi latrophilin 2 splice variant baaae 0.0008 0.0068 0.0104
Trypanosoma brucei unspecified product 0.0004 0.002 0.007
Trypanosoma brucei delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0003 0.0008 0.0021
Schistosoma mansoni opsin-like receptor 0.0102 0.1225 0.3432
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 0.0003 0.0008 0.0014
Echinococcus granulosus expressed protein 0.0007 0.0057 0.014
Loa Loa (eye worm) RNA binding protein 0.0016 0.0161 0.0253
Plasmodium falciparum importin beta, putative 0.0007 0.0052 0.052
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0026 0.0286 0.0801
Schistosoma mansoni hypothetical protein 0.0004 0.0013 0.0037
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0102 0.1225 0.3432
Brugia malayi ImpB/MucB/SamB family protein 0.0004 0.002 0.003
Brugia malayi Death domain containing protein 0.0011 0.01 0.0154
Brugia malayi larval opioid receptor 0.0102 0.1225 0.1919
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0005 0.0022 0.0022
Schistosoma mansoni notch 0.0018 0.0185 0.0519
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0065 0.0773 0.121
Entamoeba histolytica Ras family GTPase 0.0038 0.0439 0.6225
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0005 0.0029 0.0046
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0003 0.0006 0.0017
Echinococcus multilocularis neuropeptide s receptor 0.0333 0.4083 0.4083
Brugia malayi nuclear receptor NHR-67 0.0031 0.0347 0.0542
Schistosoma mansoni hypothetical protein 0.0007 0.0049 0.0136
Echinococcus granulosus rhodopsin orphan GPCR 0.0102 0.1225 0.2999
Loa Loa (eye worm) glutathione reductase 0.0009 0.0083 0.013
Trypanosoma brucei DNA polymerase eta, putative 0.0004 0.002 0.007
Entamoeba histolytica alpha-amylase family protein 0.0059 0.07 1
Echinococcus multilocularis BC026374 protein (S09 family) 0.0012 0.012 0.012
Brugia malayi protein kinase C II. 0.0007 0.0051 0.0078
Echinococcus multilocularis isocitrate dehydrogenase 0.0004 0.0015 0.0015
Echinococcus multilocularis glucan (1,4 alpha), branching enzyme 1 0.0026 0.0292 0.0292
Trypanosoma brucei DNA polymerase kappa, putative 0.0004 0.002 0.007
Loa Loa (eye worm) hypothetical protein 0.0004 0.0011 0.0018
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0005 0.0022 0.0034
Schistosoma mansoni serine/threonine protein kinase 0.0007 0.0051 0.0143
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0081 0.0966 0.1513
Echinococcus granulosus peptide allatostatin:somatostatin 0.0102 0.1225 0.2999
Echinococcus multilocularis fmrfamide receptor 0.0102 0.1225 0.1225
Loa Loa (eye worm) hypothetical protein 0.0018 0.0185 0.029
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0011 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0005 0.0022 0.0034
Toxoplasma gondii aldehyde dehydrogenase (NAD) family protein 0.0003 0.0008 0.0058
Schistosoma mansoni hypothetical protein 0.0102 0.1225 0.3432
Loa Loa (eye worm) hypothetical protein 0.0005 0.0022 0.0034
Echinococcus multilocularis neurogenic locus notch protein 0.0018 0.0185 0.0185
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0005 0.0022 0.0075
Brugia malayi EGF-like domain containing protein 0.0018 0.0185 0.0288
Schistosoma mansoni neuropeptide f receptor 76f 0.0102 0.1225 0.3432
Echinococcus granulosus smad 0.0004 0.0015 0.0038
Echinococcus granulosus g-protein coupled receptor 0.0102 0.1225 0.2999
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.001 0.0085 1
Schistosoma mansoni camp-response element binding protein 0.0007 0.0057 0.016
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Schistosoma mansoni zinc finger protein 0.0031 0.0347 0.0971
Echinococcus multilocularis carbonic anhydrase II 0.0191 0.2321 0.2321
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0006 0.0036 0.0485
Echinococcus granulosus mothers against decapentaplegic 5 0.0004 0.0015 0.0038
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0005 0.0022 0.0034
Onchocerca volvulus 0.0005 0.0022 0.0055
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0004 0.0011 0.0016
Echinococcus multilocularis orexin receptor type 2 0.0102 0.1225 0.1225
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0003 0.0006 0.0017
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0102 0.1225 0.3432
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0102 0.1225 0.1225
Onchocerca volvulus Deterin homolog 0.0017 0.0176 0.0656
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0018 0.0185 0.0519
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0005 0.0022 0.0053
Schistosoma mansoni gliotactin 0.0012 0.012 0.0337
Trypanosoma cruzi DNA polymerase kappa, putative 0.0004 0.002 0.007
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0003 0.0006 0.0017
Echinococcus multilocularis sterol regulatory element binding protein 0.0011 0.0096 0.0096
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0008 0.0064 0.01
Brugia malayi Nuclear hormone receptor E75 0.0031 0.0347 0.0542
Echinococcus granulosus Protein kinase C brain isozyme 0.0007 0.0051 0.0125
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0003 0.0002 0.0001
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0005 0.0022 0.0053
Loa Loa (eye worm) hypothetical protein 0.0069 0.0814 0.1276
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0347 0.0347
Schistosoma mansoni receptor protein tyrosine phosphatase r (pcptp1) 0.0005 0.0022 0.0061
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0005 0.0022 0.0022
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0005 0.0022 0.0032
Loa Loa (eye worm) hypothetical protein 0.0004 0.0019 0.0029
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0191 0.2321 0.6504
Brugia malayi diacylglycerol kinase 0.0007 0.0049 0.0075
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0004 0.0015 0.1442
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0065 0.0773 0.1212
Brugia malayi EGF-like domain containing protein 0.0018 0.0185 0.0288
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0004 0.002 0.002
Echinococcus multilocularis Ankyrin 0.0011 0.0101 0.0101
Echinococcus granulosus jun protein 0.0268 0.3284 0.8041
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0003 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Loa Loa (eye worm) hypothetical protein 0.0005 0.0022 0.0034
Echinococcus multilocularis glycine receptor subunit beta 0.0008 0.0064 0.0064
Brugia malayi neuropeptide F receptor 0.0102 0.1225 0.1919
Echinococcus granulosus biogenic amine 5HT receptor 0.0102 0.1225 0.2999
Brugia malayi Protein-tyrosine phosphatase 1 0.0005 0.0022 0.0032
Brugia malayi hypothetical protein 0.0031 0.0347 0.0542
Schistosoma mansoni tar DNA-binding protein 0.0016 0.0161 0.0452
Echinococcus multilocularis 0.0005 0.0022 0.0022
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0191 0.2321 0.8756
Brugia malayi nuclear hormone receptor family member nhr-6 0.0031 0.0347 0.0542
Giardia lamblia High cysteine protein 0.0018 0.0185 0.6311
Schistosoma mansoni jun-related protein 0.0218 0.2662 0.7461
Brugia malayi EGF-like domain containing protein 0.0018 0.0185 0.0288
Schistosoma mansoni acetylcholine receptor subunit beta 0.0004 0.0011 0.0031
Brugia malayi Carboxylesterase family protein 0.0074 0.0879 0.1376
Brugia malayi hypothetical protein 0.0004 0.0011 0.0016
Loa Loa (eye worm) latrophilin receptor protein 2 0.0004 0.0013 0.0021
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0003 0.0008 0.0021
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0003 0.0008 0.0021
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0004 0.002 0.005
Trypanosoma brucei DNA polymerase kappa, putative 0.0004 0.002 0.007
Brugia malayi Muscle positioning protein 4 0.0018 0.0185 0.0288
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0005 0.0022 0.0022
Brugia malayi Variant SH3 domain containing protein 0.0007 0.0049 0.0075
Schistosoma mansoni hypothetical protein 0.0072 0.0854 0.2394
Loa Loa (eye worm) hypothetical protein 0.0034 0.0392 0.0615
Echinococcus multilocularis neuropeptide receptor 0.0102 0.1225 0.1225
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0102 0.1225 0.3432
Trichomonas vaginalis ras-dva small GTPase, putative 0.0038 0.0439 0.6256
Schistosoma mansoni opsin-like receptor 0.0102 0.1225 0.3432
Echinococcus multilocularis fibropellin Ia 0.0018 0.0185 0.0185
Schistosoma mansoni neuropeptide F-like receptor 0.0102 0.1225 0.3432
Schistosoma mansoni hypothetical protein 0.0102 0.1225 0.3432
Brugia malayi hypothetical protein 0.0005 0.0022 0.0032
Loa Loa (eye worm) notch protein 0.0018 0.0185 0.029
Brugia malayi TAR-binding protein 0.0016 0.0161 0.0251
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0025 0.027 0.3782
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0102 0.1225 0.3432
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0005 0.0029 0.0104
Echinococcus granulosus dnaJ subfamily B 0.0104 0.1247 0.3053
Loa Loa (eye worm) hypothetical protein 0.0003 0.0008 0.0012
Echinococcus granulosus carbonic anhydrase 0.0081 0.0966 0.2366
Entamoeba histolytica diacylglycerol kinase, putative 0.0007 0.0049 0.0593
Brugia malayi Carboxylesterase family protein 0.0012 0.012 0.0187
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Leishmania major aldehyde dehydrogenase, putative 0.0003 0.0008 0.0021
Echinococcus granulosus transient receptor potential cation channel 0.0003 0.0001 0.0003
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0005 0.0022 0.0034
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0005 0.0022 0.0053
Echinococcus multilocularis neuropeptide receptor 0.0102 0.1225 0.1225
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0003 0.0002 0.0005
Schistosoma mansoni thyroid hormone receptor 0.0065 0.0773 0.2166
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0005 0.0022 0.0034
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0003 0.0002 0.0002
Trypanosoma cruzi DNA polymerase kappa, putative 0.0004 0.002 0.007
Loa Loa (eye worm) CXXC zinc finger family protein 0.0007 0.0056 0.0088
Loa Loa (eye worm) hypothetical protein 0.0054 0.0631 0.099
Loa Loa (eye worm) hypothetical protein 0.0008 0.0064 0.01
Toxoplasma gondii NADPH-glutathione reductase 0.0003 0.0006 0.0047
Schistosoma mansoni alpha-1 adrenergic receptor 0.0102 0.1225 0.3432
Schistosoma mansoni serine/threonine protein kinase 0.0007 0.0051 0.0143
Loa Loa (eye worm) raf kinase 0.0007 0.0049 0.0076
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0005 0.0022 0.0022
Trypanosoma brucei DNA polymerase IV, putative 0.0004 0.002 0.007
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0005 0.0022 0.0034
Brugia malayi protein kinase C3,putative 0.0007 0.0051 0.0078
Loa Loa (eye worm) acetylcholinesterase 1 0.0074 0.0879 0.1378
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0004 0.0015 0.0043
Echinococcus multilocularis carbonic anhydrase 0.0081 0.0966 0.0966
Trypanosoma cruzi PAB1-binding protein , putative 0.0006 0.0044 0.0158
Trypanosoma brucei unspecified product 0.0003 0.0004 0.0006
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.072 0.2019
Brugia malayi Calcitonin receptor-like protein seb-1 0.0012 0.0115 0.0178
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0024 0.0261 0.0261
Mycobacterium ulcerans trehalose synthase TreS 0.0007 0.0046 0.0501
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0519 0.6378 1
Mycobacterium ulcerans DNA polymerase IV 0.0004 0.002 0.0175
Brugia malayi neuropeptide F receptor 0.0102 0.1225 0.1919
Schistosoma mansoni nAChR subunit 0.0008 0.0064 0.0179
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0102 0.1225 0.3432
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0065 0.0773 0.1212
Echinococcus multilocularis expressed protein 0.0007 0.0057 0.0057
Entamoeba histolytica Pten 3-phosphoinositide phosphatase, putative 0.0005 0.0022 0.0205
Loa Loa (eye worm) bZIP transcription factor family protein 0.0007 0.0057 0.0089
Schistosoma mansoni neurotransmitter gated ion channel 0.0004 0.0019 0.0053
Onchocerca volvulus 0.0102 0.1225 0.4748
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.072 0.8964
Schistosoma mansoni importin beta-1 0.0007 0.0052 0.0146
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0003 0.0006 0.0017
Schistosoma mansoni notch 0.0018 0.0185 0.0519
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0102 0.1225 0.192
Trypanosoma brucei PAB1-binding protein , putative 0.0006 0.0044 0.0158
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0004 0.002 0.0265
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0007 0.0051 0.008
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0004 0.0015 0.0041
Echinococcus multilocularis protein tyrosine phosphatase n9 0.0005 0.0022 0.0022
Trypanosoma brucei protein tyrosine phosphatase 1 0.0005 0.0022 0.0075
Loa Loa (eye worm) hypothetical protein 0.0005 0.0022 0.0034
Loa Loa (eye worm) hypothetical protein 0.0008 0.0064 0.01
Schistosoma mansoni thyroid hormone receptor 0.0065 0.0773 0.2166
Giardia lamblia Kinesin-5 0.001 0.0091 0.3068
Onchocerca volvulus 0.0005 0.0022 0.0055
Schistosoma mansoni peroxidasin 0.0069 0.0814 0.228
Schistosoma mansoni myosin xvIII 0.0102 0.1225 0.3432
Loa Loa (eye worm) hypothetical protein 0.0007 0.0049 0.0076
Loa Loa (eye worm) hypothetical protein 0.0005 0.0022 0.0034
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0102 0.1225 0.1225
Echinococcus granulosus g protein coupled receptor 0.0102 0.1225 0.2999
Onchocerca volvulus 0.0007 0.0049 0.016
Trypanosoma brucei carbonic anhydrase-like protein 0.0191 0.2321 0.8756
Entamoeba histolytica oligo-1,6-glucosidase, putative 0.0007 0.0046 0.056
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0003 0.0006 0.0016
Schistosoma mansoni amine GPCR 0.0102 0.1225 0.3432
Echinococcus granulosus protein jagged 2 0.0018 0.0185 0.0453
Echinococcus granulosus Rac GTPase activating protein 1 0.0007 0.0049 0.0119
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0065 0.0773 0.0773
Echinococcus granulosus glycine receptor subunit beta 0.0008 0.0064 0.0156
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0008 0.0064 0.0098
Brugia malayi Smad1 0.0004 0.0015 0.0022
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0191 0.2321 0.3639
Entamoeba histolytica diacylglycerol kinase, putative 0.0007 0.0049 0.0593
Onchocerca volvulus 0.0012 0.012 0.044
Brugia malayi Animal haem peroxidase family protein 0.0069 0.0814 0.1274
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0102 0.1225 0.2999
Onchocerca volvulus 0.0069 0.0814 0.3144
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0005 0.0022 0.0053
Echinococcus multilocularis rhodopsin orphan GPCR 0.0102 0.1225 0.1225
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0005 0.0029 0.0104
Loa Loa (eye worm) hypothetical protein 0.0069 0.0814 0.1276
Onchocerca volvulus 0.0031 0.0347 0.1322
Schistosoma mansoni laminin gamma-3 chain 0.0018 0.0185 0.0519
Brugia malayi RE15519p 0.0102 0.1225 0.1919
Brugia malayi orphan nuclear receptor NR2E1 0.0031 0.0347 0.0542
Echinococcus granulosus GPCR family 2 0.0004 0.0013 0.0032
Loa Loa (eye worm) hypothetical protein 0.0004 0.0011 0.0018
Loa Loa (eye worm) hypothetical protein 0.0008 0.0064 0.01
Onchocerca volvulus 0.0069 0.0814 0.3144
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0004 0.0011 0.0011
Entamoeba histolytica alpha-amylase, putative 0.0007 0.0046 0.056
Schistosoma mansoni neuropeptide receptor 0.0102 0.1225 0.3432
Echinococcus granulosus rhodopsin orphan GPCR 0.0102 0.1225 0.2999
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0005 0.0022 0.0032
Schistosoma mansoni pcd6 interacting protein-related 0.0005 0.0022 0.0061
Onchocerca volvulus 0.0102 0.1225 0.4748
Echinococcus granulosus carbonic anhydrase 0.0081 0.0966 0.2366
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.001 0.0085 0.0992
Trichomonas vaginalis ral, putative 0.0038 0.0439 0.6256
Mycobacterium tuberculosis Carboxylesterase LipT 0.0012 0.012 0.1429
Toxoplasma gondii hypothetical protein 0.0081 0.0966 1
Echinococcus multilocularis protein dispatched 1 0.0012 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0008 0.0064 0.01
Echinococcus multilocularis neurogenic locus notch protein 0.0018 0.0185 0.0185
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Loa Loa (eye worm) TYRA-2 protein 0.0102 0.1225 0.192
Mycobacterium tuberculosis 1,4-alpha-glucan branching enzyme GlgB (glycogen branching enzyme) 0.0026 0.0292 0.3588
Loa Loa (eye worm) hypothetical protein 0.0005 0.0022 0.0034
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.072 0.8964
Mycobacterium tuberculosis Probable reductase 0.0022 0.0232 0.2833
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0065 0.0773 0.1892
Loa Loa (eye worm) hypothetical protein 0.0049 0.0573 0.0898
Brugia malayi Protein kinase domain containing protein 0.0011 0.0102 0.0158
Echinococcus granulosus glycine receptor subunit alpha 1 0.0008 0.0064 0.0156
Brugia malayi G-protein coupled receptor 0.0102 0.1225 0.1919
Brugia malayi hypothetical protein 0.0102 0.1225 0.1919
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0008 0.0064 0.0179
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Schistosoma mansoni hypothetical protein 0.001 0.0092 0.0257
Loa Loa (eye worm) hypothetical protein 0.0031 0.0347 0.0543
Trichomonas vaginalis alpha-amylase, putative 0.0007 0.0046 0.0636
Leishmania major DNA polymerase eta, putative 0.0004 0.002 0.007
Loa Loa (eye worm) hypothetical protein 0.0026 0.0292 0.0458
Leishmania major squalene synthase, putative 0.0217 0.265 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0003 0.0006 0.0017
Onchocerca volvulus 0.0007 0.0056 0.0189
Loa Loa (eye worm) hypothetical protein 0.0005 0.0022 0.0034
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0004 0.0015 0.0048
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0008 0.0064 0.01
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0003 0.0002 0.0005
Echinococcus granulosus protein kinase c iota type 0.0007 0.0051 0.0125
Loa Loa (eye worm) hypothetical protein 0.0005 0.0022 0.0034
Schistosoma mansoni hypothetical protein 0.0068 0.0803 0.225
Trichomonas vaginalis ap endonuclease, putative 0.001 0.0085 0.1196
Brugia malayi Carboxylesterase family protein 0.0012 0.012 0.0187
Brugia malayi hypothetical protein 0.0036 0.0411 0.0643
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0004 0.0011 0.0018
Schistosoma mansoni hypothetical protein 0.0004 0.0013 0.0037
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0003 0.0002 0.0001
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0017 0.0176 0.0431
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0065 0.0773 0.2166
Loa Loa (eye worm) hypothetical protein 0.0008 0.0064 0.01
Echinococcus multilocularis nAChR subunit 0.0008 0.0064 0.0064
Echinococcus granulosus neuropeptide receptor 0.0102 0.1225 0.2999
Toxoplasma gondii isocitrate dehydrogenase 0.0004 0.0015 0.0133
Echinococcus granulosus neuropeptide receptor 0.0102 0.1225 0.2999
Loa Loa (eye worm) alpha amylase 0.0007 0.0046 0.0073
Entamoeba histolytica exodeoxyribonuclease III, putative 0.001 0.0085 0.1124
Echinococcus granulosus notch 0.0018 0.0185 0.0453
Plasmodium vivax ataxin-2 like protein, putative 0.0006 0.0044 0.4699
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0003 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0102 0.1225 0.3432
Schistosoma mansoni hypothetical protein 0.0007 0.0046 0.013
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0102 0.1225 0.192
Leishmania major squalene monooxygenase-like protein 0.0197 0.2405 0.9075
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0191 0.2321 0.3638
Onchocerca volvulus 0.0054 0.0631 0.2434
Loa Loa (eye worm) hypothetical protein 0.0018 0.0185 0.029
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0065 0.0773 0.121
Trichomonas vaginalis starch branching enzyme II, putative 0.0026 0.0292 0.4155
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.001 0.0085 0.0315
Loa Loa (eye worm) hypothetical protein 0.0007 0.0049 0.0076
Trichomonas vaginalis alpha-amylase, putative 0.0053 0.062 0.885
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Brugia malayi photoreceptor-specific nuclear receptor 0.0065 0.0773 0.121
Schistosoma mansoni cpg binding protein 0.0007 0.0056 0.0157
Brugia malayi Peroxidasin 0.0069 0.0814 0.1274
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0065 0.0773 0.2166
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0008 0.0064 0.0098
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0061 0.0717 0.1123
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0017 0.0176 0.0493
Schistosoma mansoni hypothetical protein 0.0003 0.0008 0.0021
Loa Loa (eye worm) carboxylesterase 0.0012 0.012 0.0189
Echinococcus granulosus tachykinin peptides receptor 99D 0.0102 0.1225 0.2999
Schistosoma mansoni biogenic amine (5HT) receptor 0.0102 0.1225 0.3432
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Loa Loa (eye worm) protein tyrosine phosphatase 0.0005 0.0022 0.0034
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0102 0.1225 0.1225
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0102 0.1225 0.1225
Echinococcus multilocularis N chimaerin 0.0007 0.0049 0.0049
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0102 0.1225 0.1225
Brugia malayi MH1 domain containing protein 0.0004 0.0015 0.0022
Schistosoma mansoni amine GPCR 0.0102 0.1225 0.3432
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0003 0.0002 0.0005
Echinococcus multilocularis aldehyde dehydrogenase family 3 member B1 0.0003 0.0008 0.0008
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0018 0.0185 0.0693
Onchocerca volvulus Neuropeptide F receptor homolog 0.0102 0.1225 0.4748
Trichomonas vaginalis alpha-amylase, putative 0.0007 0.0046 0.0636
Echinococcus multilocularis neuropeptide Y receptor 0.0102 0.1225 0.1225
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0041 0.0471 0.1153
Toxoplasma gondii LsmAD domain-containing protein 0.0006 0.0044 0.0434
Schistosoma mansoni neurotransmitter gated ion channel 0.0004 0.0011 0.0031
Schistosoma mansoni tar DNA-binding protein 0.0016 0.0161 0.0452
Plasmodium falciparum ataxin-2 like protein, putative 0.0006 0.0044 0.0434
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0034 0.0392 0.1099
Echinococcus granulosus nAChR subunit 0.0004 0.0019 0.0046
Schistosoma mansoni ap endonuclease 0.001 0.0085 0.0239
Schistosoma mansoni serine/threonine protein kinase 0.0007 0.0051 0.0143
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0008 0.0064 0.0098
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0024 0.0261 0.8917
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0004 0.0015 0.0048
Trypanosoma brucei DNA polymerase kappa, putative 0.0004 0.002 0.007
Loa Loa (eye worm) DR-78 0.0031 0.0347 0.0543
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0102 0.1225 0.1225
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0065 0.0773 0.2985
Loa Loa (eye worm) hypothetical protein 0.0004 0.0019 0.0029
Loa Loa (eye worm) bZIP transcription factor family protein 0.0007 0.0057 0.0089
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0004 0.0015 0.0015
Trichomonas vaginalis pten, drome, putative 0.0005 0.0022 0.0284
Onchocerca volvulus 0.0005 0.0022 0.0055
Schistosoma mansoni nuclear receptor 0.0031 0.0347 0.0971
Brugia malayi Niemann-Pick C1 protein precursor 0.0025 0.027 0.0421
Trypanosoma brucei DNA polymerase IV, putative 0.0004 0.002 0.007
Entamoeba histolytica alpha-amylase family protein 0.0007 0.0046 0.056
Plasmodium vivax kinesin-5 0.001 0.0091 1
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0102 0.1225 0.1919
Echinococcus multilocularis GPCR, family 2 0.0004 0.0013 0.0013
Onchocerca volvulus 0.0031 0.0347 0.1322
Mycobacterium tuberculosis Probable phytoene synthase PhyA 0.0068 0.0803 1
Echinococcus multilocularis protein jagged 2 0.0018 0.0185 0.0185
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0021 0.0225 0.0353
Schistosoma mansoni rac gtpase activating protein 0.0007 0.0049 0.0136
Loa Loa (eye worm) hypothetical protein 0.0005 0.0022 0.0034
Echinococcus multilocularis rhodopsin orphan GPCR 0.0102 0.1225 0.1225
Echinococcus granulosus TGF beta signal transducer SmadC 0.0004 0.0015 0.0038
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.001 0.0085 0.2878
Leishmania major hypothetical protein, conserved 0.0006 0.0044 0.0158
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0096 0.1351
Trypanosoma brucei DNA polymerase kappa, putative 0.0003 0.0004 0.0006
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0268 0.3284 0.3284
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0017 0.0176 0.0176
Loa Loa (eye worm) steroid hormone receptor 0.0065 0.0773 0.1212
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0005 0.0022 0.0053
Trypanosoma brucei unspecified product 0.0003 0.0004 0.0006
Schistosoma mansoni smad 0.0004 0.0015 0.0043
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0005 0.0022 0.0061
Brugia malayi ImpB/MucB/SamB family protein 0.0004 0.002 0.003
Echinococcus multilocularis cpg binding protein 0.0008 0.0061 0.0061
Echinococcus granulosus glycine receptor subunit alpha 1 0.0008 0.0064 0.0156
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0102 0.1225 0.3432
Leishmania major carbonic anhydrase-like protein 0.0191 0.2321 0.8756
Schistosoma mansoni camp-response element binding protein-related 0.0007 0.0057 0.016
Schistosoma mansoni hypothetical protein 0.0018 0.0185 0.0519
Onchocerca volvulus 0.0005 0.0022 0.0055
Echinococcus multilocularis carbonic anhydrase 0.0081 0.0966 0.0966
Onchocerca volvulus Protein ultraspiracle homolog 0.0065 0.0773 0.2985
Onchocerca volvulus Putative nachr subunit 0.0008 0.0064 0.022
Loa Loa (eye worm) hypothetical protein 0.0008 0.0064 0.01
Schistosoma mansoni biogenic amine (5HT) receptor 0.0102 0.1225 0.3432
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0003 0.0006 0.051
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0081 0.0966 0.1513
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0004 0.0015 0.0133
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0003 0.0002 0.0005
Schistosoma mansoni nuclear receptor 0.0031 0.0347 0.0971
Schistosoma mansoni tar DNA-binding protein 0.0016 0.0161 0.0452
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0005 0.0022 0.0032
Schistosoma mansoni carbonic anhydrase 0.0081 0.0966 0.2708
Echinococcus granulosus snurportin 1 0.0074 0.0885 0.2167
Brugia malayi Animal haem peroxidase family protein 0.0069 0.0814 0.1274
Schistosoma mansoni ap endonuclease 0.001 0.0085 0.0239
Brugia malayi RNA, U transporter 1 0.002 0.0211 0.0329
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0065 0.0773 0.121
Schistosoma mansoni amine GPCR 0.0102 0.1225 0.3432
Echinococcus granulosus ecdysone induced protein 78C 0.0065 0.0773 0.1892
Echinococcus granulosus cyclic AMP responsive element binding protein 0.0007 0.0057 0.014
Loa Loa (eye worm) hypothetical protein 0.0018 0.0185 0.029
Loa Loa (eye worm) hypothetical protein 0.0005 0.0022 0.0034
Echinococcus granulosus peroxidasin 0.0069 0.0814 0.1993
Loa Loa (eye worm) hypothetical protein 0.0005 0.0022 0.0034
Onchocerca volvulus Netrin receptor homolog 0.0011 0.01 0.0359
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0102 0.1225 0.3432
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0065 0.0773 0.0773
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0065 0.0773 0.0773
Onchocerca volvulus Peroxidasin homolog 0.0069 0.0814 0.3144
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0074 0.0885 0.1387
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0003 0.0006 0.0017
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0411 0.1152
Brugia malayi hypothetical protein 0.0102 0.1225 0.1919
Brugia malayi hypothetical protein 0.0005 0.0022 0.0032
Mycobacterium ulcerans gamma-aminobutyraldehyde dehydrogenase 0.0003 0.0008 0.0014
Loa Loa (eye worm) animal heme peroxidase 0.0069 0.0814 0.1276
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.001 0.0085 0.0315
Toxoplasma gondii alpha amylase, catalytic domain-containing protein 0.0026 0.0292 0.301
Loa Loa (eye worm) hypothetical protein 0.0018 0.0185 0.029
Brugia malayi hypothetical protein 0.0022 0.0238 0.0371
Loa Loa (eye worm) blistered cuticle protein 3 0.0069 0.0814 0.1276
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Onchocerca volvulus 0.0005 0.0022 0.0055
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0102 0.1225 0.1225
Loa Loa (eye worm) hypothetical protein 0.0026 0.0286 0.0448
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0005 0.0022 0.0032
Schistosoma mansoni DNA polymerase eta 0.0004 0.002 0.0057
Loa Loa (eye worm) hypothetical protein 0.0005 0.0022 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0065 0.0773 0.121
Echinococcus multilocularis carbonic anhydrase 0.0081 0.0966 0.0966
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0003 0.0008 0.0021
Wolbachia endosymbiont of Brugia malayi bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 0.0003 0.0008 0.0138
Onchocerca volvulus 0.0102 0.1225 0.4748
Loa Loa (eye worm) nuclear receptor NHR-67 0.0031 0.0347 0.0543
Loa Loa (eye worm) hypothetical protein 0.0005 0.0022 0.0034
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0074 0.0879 0.2462
Echinococcus granulosus neuroligin 0.0012 0.012 0.0294
Echinococcus granulosus acetylcholinesterase 0.0074 0.0879 0.2152
Brugia malayi bZIP transcription factor family protein 0.0007 0.0057 0.0088
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0012 0.0115 0.018
Schistosoma mansoni aldehyde dehydrogenase 0.0003 0.0008 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0065 0.0773 0.121
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0031 0.0347 0.1322
Onchocerca volvulus 0.0005 0.0022 0.0055
Loa Loa (eye worm) hypothetical protein 0.0008 0.0064 0.01
Echinococcus multilocularis X box binding protein 1 0.0072 0.0854 0.0854
Schistosoma mansoni histamine h1 receptor 0.0102 0.1225 0.3432
Echinococcus multilocularis rhodopsin orphan GPCR 0.0102 0.1225 0.1225
Loa Loa (eye worm) hypothetical protein 0.0065 0.0773 0.1212
Schistosoma mansoni aldehyde dehydrogenase 0.0003 0.0008 0.0021
Trypanosoma cruzi trypanothione reductase, putative 0.0009 0.0083 0.0305
Loa Loa (eye worm) hypothetical protein 0.0005 0.0022 0.0034
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0005 0.0022 0.0022
Onchocerca volvulus 0.0012 0.012 0.044
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0065 0.0773 0.121
Loa Loa (eye worm) hypothetical protein 0.0003 0.0002 0.0003
Echinococcus multilocularis fos transcription factor 0.0007 0.0057 0.0057
Mycobacterium tuberculosis Probable aldehyde dehydrogenase NAD dependent AldA (aldehyde dehydrogenase [NAD+]) 0.0003 0.0008 0.0014
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0005 0.0022 0.0032
Brugia malayi hypothetical protein 0.0007 0.0057 0.0088
Loa Loa (eye worm) hypothetical protein 0.0018 0.0185 0.029
Onchocerca volvulus 0.0102 0.1225 0.4748
Onchocerca volvulus 0.0102 0.1225 0.4748
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Echinococcus granulosus neural cadherin 0.0018 0.0185 0.0453
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0003 0.0008 0.0021
Echinococcus granulosus GTP binding nuclear protein Ran 0.0005 0.0029 0.0072
Chlamydia trachomatis 1,4-alpha-glucan branching enzyme 0.0026 0.0292 1
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0004 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0007 0.0049 0.0076
Loa Loa (eye worm) hypothetical protein 0.0004 0.0019 0.0029
Loa Loa (eye worm) hypothetical protein 0.0031 0.0347 0.0543
Echinococcus granulosus Smad4 0.0004 0.0015 0.0038
Loa Loa (eye worm) carboxylesterase 0.0074 0.0879 0.1378
Loa Loa (eye worm) hypothetical protein 0.0005 0.0022 0.0034
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0008 0.0064 0.0064
Echinococcus granulosus aldehyde dehydrogenase family 3 member B1 0.0003 0.0008 0.0019
Schistosoma mansoni hypothetical protein 0.0008 0.0068 0.019
Loa Loa (eye worm) hypothetical protein 0.0018 0.0185 0.029
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0102 0.1225 0.3432
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0005 0.0022 0.0032
Loa Loa (eye worm) hypothetical protein 0.0008 0.0064 0.01
Loa Loa (eye worm) protein-tyrosine-phosphatase 0.0005 0.0022 0.0034
Loa Loa (eye worm) hypothetical protein 0.0008 0.0064 0.01
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0017 0.0176 0.0274
Schistosoma mansoni diacylglycerol kinase theta 0.0007 0.0049 0.0136
Echinococcus multilocularis acetylcholinesterase 0.0074 0.0879 0.0879
Echinococcus granulosus glycine receptor subunit beta 0.0008 0.0064 0.0156
Loa Loa (eye worm) hypothetical protein 0.0007 0.0057 0.0089
Schistosoma mansoni transient receptor potential channel 0.0003 0.0001 0.0003
Trichomonas vaginalis alpha-amylase, putative 0.0059 0.07 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0004 0.0013 0.0019
Loa Loa (eye worm) hypothetical protein 0.0069 0.0814 0.1276
Brugia malayi Importin beta-1 subunit 0.0007 0.0052 0.008
Leishmania major importin beta-1 subunit, putative 0.0006 0.0036 0.0128
Echinococcus granulosus Squalene phytoene synthase 0.0068 0.0803 0.1966
Schistosoma mansoni acetylcholinesterase 0.0012 0.012 0.0337
Echinococcus multilocularis protein patched 0.0011 0.0096 0.0096
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0008 0.0064 0.0098
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0065 0.0773 0.121
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0004 0.0015 0.0104
Trichomonas vaginalis alpha-amylase, putative 0.0007 0.0046 0.0636
Entamoeba histolytica hypothetical protein 0.0007 0.0046 0.056
Trypanosoma brucei DNA polymerase kappa, putative 0.0004 0.002 0.007
Echinococcus multilocularis cyclic AMP dependent transcription factor ATF 6 0.0007 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Loa Loa (eye worm) hypothetical protein 0.0004 0.0011 0.0018
Schistosoma mansoni hypothetical protein 0.0074 0.0885 0.2479
Onchocerca volvulus 0.0005 0.0022 0.0055
Brugia malayi MH2 domain containing protein 0.0004 0.0015 0.0022
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0003 0.0002 0.0005
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0005 0.0022 0.0022
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0008 0.0064 0.0098
Loa Loa (eye worm) hypothetical protein 0.0008 0.0064 0.01
Schistosoma mansoni cpg binding protein 0.0008 0.0061 0.0171
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0007 0.0049 0.0076
Brugia malayi MH2 domain containing protein 0.0059 0.0691 0.1082
Brugia malayi isocitrate dehydrogenase 0.0004 0.0015 0.0021
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0005 0.0022 0.0032
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0102 0.1225 0.3432
Brugia malayi Blistered cuticle protein 3 0.0069 0.0814 0.1274
Echinococcus granulosus rhodopsin orphan GPCR 0.0102 0.1225 0.2999
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0178 0.2164 0.5299
Loa Loa (eye worm) kinesin-like protein KLP2 0.001 0.0091 0.0143
Trypanosoma cruzi trypanothione reductase, putative 0.0003 0.0006 0.0017
Echinococcus granulosus calcium activated potassium channel 0.0003 0.0003 0.0006
Schistosoma mansoni acetylcholine receptor-related 0.0004 0.0011 0.0031
Mycobacterium ulcerans DNA polymerase IV 0.0004 0.002 0.0175
Brugia malayi hypothetical protein 0.0012 0.012 0.0187
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0102 0.1225 0.1225
Loa Loa (eye worm) hypothetical protein 0.0005 0.0022 0.0034
Echinococcus multilocularis calcium activated potassium channel 0.0003 0.0003 0.0003
Echinococcus multilocularis transient receptor potential cation channel 0.0003 0.0001 0.0001
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0005 0.0022 0.0061
Echinococcus granulosus 7TM GPCR rhodopsin 0.0102 0.1225 0.2999
Echinococcus granulosus g protein coupled receptor 0.0102 0.1225 0.2999
Schistosoma mansoni smad1 5 8 and 0.0004 0.0015 0.0043
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0007 0.0049 0.0119
Schistosoma mansoni smad1 5 8 and 0.0004 0.0015 0.0043
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0102 0.1225 0.192
Loa Loa (eye worm) hypothetical protein 0.0024 0.0261 0.0409
Loa Loa (eye worm) hypothetical protein 0.0065 0.0773 0.1212
Loa Loa (eye worm) hypothetical protein 0.0005 0.0022 0.0034
Echinococcus multilocularis protein kinase c epsilon type 0.0007 0.0051 0.0051
Brugia malayi hypothetical protein 0.0006 0.0044 0.0067
Loa Loa (eye worm) hypothetical protein 0.0008 0.0064 0.01
Schistosoma mansoni BC026374 protein (S09 family) 0.0012 0.012 0.0337
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0005 0.0029 0.0285
Chlamydia trachomatis glycogen hydrolase 0.0007 0.0046 0.1397
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0031 0.0347 0.0543
Schistosoma mansoni protein kinase C 0.0007 0.0049 0.0136
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0003 0.0002 0.0002
Plasmodium falciparum carbonic anhydrase 0.0081 0.0966 1
Onchocerca volvulus 0.0102 0.1225 0.4748
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0004 0.0011 0.0018
Schistosoma mansoni vav2 0.0008 0.0071 0.0199
Brugia malayi CXXC zinc finger family protein 0.0007 0.0056 0.0086
Onchocerca volvulus Chorion peroxidase homolog 0.0069 0.0814 0.3144
Schistosoma mansoni coup transcription factor 0.0065 0.0773 0.2166
Echinococcus granulosus nAChR subunit 0.0008 0.0064 0.0156
Echinococcus granulosus sterol regulatory element binding protein 0.0011 0.0096 0.0236
Onchocerca volvulus 0.0017 0.0176 0.0656
Brugia malayi hypothetical protein 0.0005 0.0022 0.0032
Trichomonas vaginalis importin beta-1, putative 0.0006 0.0036 0.0485
Echinococcus granulosus dro:myosuppressin receptor 0.0102 0.1225 0.2999
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0031 0.0347 0.0347
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0004 0.002 0.0032
Loa Loa (eye worm) aldehyde dehydrogenase 0.0003 0.0008 0.0012
Echinococcus granulosus X box binding protein 1 0.0072 0.0854 0.2092
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.072 0.072
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0191 0.2321 0.6504
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0003 0.0006 0.0017
Schistosoma mansoni inhibitor of apoptosis protein 0.0017 0.0176 0.0493
Loa Loa (eye worm) carbonic anhydrase 3 0.0191 0.2321 0.3639
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0005 0.0022 0.0205
Trichomonas vaginalis ap endonuclease, putative 0.001 0.0085 0.1196
Trypanosoma cruzi DNA polymerase kappa, putative 0.0004 0.002 0.007
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0065 0.0773 0.1892
Brugia malayi G-protein coupled receptor 0.0102 0.1225 0.1919
Echinococcus granulosus hypothetical protein 0.0102 0.1225 0.2999
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0005 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Brugia malayi Cation transporter family protein 0.0008 0.0064 0.0098
Loa Loa (eye worm) hypothetical protein 0.0018 0.0185 0.029
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0003 0.0008 0.0014
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0065 0.0773 0.2166
Schistosoma mansoni nAChR subunit 0.0004 0.0011 0.0031
Schistosoma mansoni hypothetical protein 0.0291 0.3568 1
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0081 0.0966 0.1513
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Mycobacterium tuberculosis Probable oxidoreductase 0.0024 0.0262 0.3206
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0003 0.0008 0.0014
Brugia malayi Carboxylesterase family protein 0.0012 0.012 0.0187
Schistosoma mansoni eyes absent homolog 0.0022 0.0238 0.0666
Schistosoma mansoni adenoreceptor 0.0102 0.1225 0.3432
Brugia malayi Nuclear hormone receptor-like 1 0.0034 0.0392 0.0613
Loa Loa (eye worm) hypothetical protein 0.0038 0.0439 0.0688
Trichomonas vaginalis ran, putative 0.0005 0.0029 0.0393
Trypanosoma brucei DNA polymerase kappa, putative 0.0004 0.002 0.007
Echinococcus multilocularis rhodopsin orphan GPCR 0.0102 0.1225 0.1225
Brugia malayi nuclear receptor NHR-88 0.0065 0.0773 0.121
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0007 0.0049 0.0049
Brugia malayi RhoGAP domain containing protein 0.0007 0.0049 0.0075
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0003 0.0008 0.0021
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0005 0.0022 0.0053
Loa Loa (eye worm) LGC-31 protein 0.0008 0.0064 0.01
Loa Loa (eye worm) hypothetical protein 0.0031 0.0347 0.0543
Leishmania major pyrroline-5-carboxylate synthetase-like protein 0.0003 0.0008 0.0021
Brugia malayi Alpha amylase, catalytic domain containing protein 0.0007 0.0046 0.0071
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0178 0.2164 0.2164
Schistosoma mansoni protein tyrosine phosphatase 0.0005 0.0022 0.0061
Echinococcus granulosus thyroid hormone receptor alpha 0.0031 0.0347 0.0849
Onchocerca volvulus 0.0102 0.1225 0.4748
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0065 0.0773 0.121
Schistosoma mansoni nAChR subunit 0.0008 0.0064 0.0179
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0031 0.0347 0.0542
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0005 0.0022 0.0053
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0007 0.0051 0.0051
Echinococcus granulosus unc 13 munc13 0.0007 0.0049 0.0119
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0065 0.0773 0.0773
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0004 0.0019 0.0053
Echinococcus granulosus acetylcholinesterase 0.0074 0.0879 0.2152
Loa Loa (eye worm) hypothetical protein 0.0005 0.0022 0.0034
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0008 0.0064 0.0098
Echinococcus multilocularis hypothetical protein 0.0005 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Echinococcus multilocularis importin subunit beta 1 0.0007 0.0052 0.0052
Onchocerca volvulus 0.0102 0.1225 0.4748
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0191 0.2321 0.3638
Mycobacterium tuberculosis Maltooligosyltrehalose trehalohydrolase TreZ 0.0007 0.0046 0.0501
Loa Loa (eye worm) thioredoxin reductase 0.0009 0.0083 0.013
Trichomonas vaginalis alpha-amylase, putative 0.0007 0.0046 0.0636
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0012 0.012 0.1694
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0102 0.1225 0.2999
Schistosoma mansoni nAChR subunit 0.0008 0.0064 0.0179
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0102 0.1225 0.1919
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0347 0.0971
Plasmodium falciparum thioredoxin reductase 0.0009 0.0083 0.0837
Brugia malayi CHE-14 protein 0.0011 0.0096 0.0149
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0268 0.3284 0.8041
Schistosoma mansoni neuropeptide receptor 0.0102 0.1225 0.3432
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0411 0.0411
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0005 0.0022 0.0032
Brugia malayi hypothetical protein 0.0005 0.0022 0.0032
Echinococcus granulosus carbonic anhydrase II 0.0191 0.2321 0.5684
Mycobacterium tuberculosis Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialde 0.0003 0.0008 0.0014
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0008 0.0064 0.0179
Brugia malayi Delta serrate ligand family protein 0.0018 0.0185 0.0288
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0005 0.0022 0.0032
Loa Loa (eye worm) hypothetical protein 0.0018 0.0185 0.029
Schistosoma mansoni alpha-amylase 0.0007 0.0046 0.013
Loa Loa (eye worm) delta-1-pyrroline-5-carboxylate dehydrogenase 0.0003 0.0008 0.0012
Loa Loa (eye worm) hypothetical protein 0.0006 0.0044 0.0069
Schistosoma mansoni notch 0.0018 0.0185 0.0519
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0007 0.0051 0.008
Echinococcus multilocularis tar DNA binding protein 0.0016 0.0161 0.0161
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0003 0.0006 0.0008
Onchocerca volvulus 0.0005 0.0022 0.0055
Schistosoma mansoni unc-13 (munc13) 0.0007 0.0049 0.0136
Toxoplasma gondii thioredoxin reductase 0.0009 0.0083 0.0837
Loa Loa (eye worm) hypothetical protein 0.0018 0.0185 0.029
Echinococcus granulosus short transient receptor potential channel 6 0.0003 0.0001 0.0003
Echinococcus granulosus Fatty aldehyde dehydrogenase 0.0003 0.0008 0.0019
Brugia malayi Dopamine receptor protein 1 0.0102 0.1225 0.1919
Loa Loa (eye worm) hypothetical protein 0.0018 0.0185 0.029
Loa Loa (eye worm) PDE1B protein 0.0003 0.0002 0.0003
Brugia malayi excitatory GABA receptor EXP-1A 0.0008 0.0064 0.0098
Brugia malayi RNA recognition motif domain containing protein 0.0016 0.0161 0.0251
Echinococcus granulosus biogenic amine 5HT receptor 0.0102 0.1225 0.2999
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0004 0.0015 0.0048
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0065 0.0773 0.121
Loa Loa (eye worm) hypothetical protein 0.0007 0.0052 0.0082
Loa Loa (eye worm) hypothetical protein 0.0018 0.0185 0.029
Brugia malayi G protein-coupled receptor 0.0102 0.1225 0.1919
Entamoeba histolytica kinesin, putative 0.001 0.0091 0.1204
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0005 0.0022 0.0022
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0011 0.01 0.0156
Echinococcus granulosus neuropeptide Y receptor 0.0102 0.1225 0.2999
Brugia malayi exodeoxyribonuclease III family protein 0.001 0.0085 0.0132
Echinococcus granulosus rhodopsin orphan GPCR 0.0102 0.1225 0.2999
Onchocerca volvulus NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 homolog 0.0068 0.0803 0.3102
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0005 0.0022 0.0032
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0003 0.0006 0.0047
Plasmodium vivax importin-beta 2, putative 0.0007 0.0052 0.5636
Leishmania major tyrosine specific protein phosphatase, putative 0.0005 0.0022 0.0075
Schistosoma mansoni carbonic anhydrase-related 0.0081 0.0966 0.2708
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0005 0.0022 0.0022
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0008 0.0064 0.0064
Brugia malayi Immunoglobulin I-set domain containing protein 0.0011 0.01 0.0154
Echinococcus multilocularis neuropeptide Y receptor 0.0102 0.1225 0.1225
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0008 0.0064 0.0098
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0016 0.0161 0.0253
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0008 0.0064 0.0064
Echinococcus multilocularis neurogenic locus protein delta 0.0018 0.0185 0.0185
Onchocerca volvulus 0.0018 0.0185 0.0693
Brugia malayi small heat shock protein 0.0437 0.5368 0.8416
Loa Loa (eye worm) hypothetical protein 0.0008 0.0064 0.01
Brugia malayi EGF-like domain containing protein 0.0018 0.0185 0.0288
Treponema pallidum exodeoxyribonuclease (exoA) 0.001 0.0085 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0102 0.1225 0.2999
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0003 0.0006 0.0017
Schistosoma mansoni alpha-amylase 0.0007 0.0046 0.013
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0008 0.0064 0.0064
Trichomonas vaginalis GTP-binding protein rit, putative 0.0038 0.0439 0.6256
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.072 0.8964
Echinococcus multilocularis fmrfamide receptor 0.0102 0.1225 0.1225
Schistosoma mansoni nuclear hormone receptor 0.0065 0.0773 0.2166
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0065 0.0773 0.1892
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0005 0.0022 0.0053
Entamoeba histolytica 1,4-alpha-glucan branching enzyme, putative 0.0026 0.0292 0.4108
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0003 0.0006 0.0017
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0005 0.0022 0.0022
Onchocerca volvulus 0.0069 0.0814 0.3144
Echinococcus multilocularis peroxidasin 0.0069 0.0814 0.0814
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0005 0.0022 0.0032
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0024 0.0261 0.0261
Echinococcus multilocularis receptor type tyrosine protein phosphatase H 0.0005 0.0022 0.0022
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0031 0.0347 0.0347
Loa Loa (eye worm) hypothetical protein 0.0018 0.0185 0.029
Echinococcus granulosus cyclic AMP dependent transcription factor ATF 6 0.0007 0.0057 0.014
Schistosoma mansoni neuroligin 3 (S09 family) 0.0012 0.012 0.0337
Onchocerca volvulus 0.0061 0.0714 0.2756
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0003 0.0002 0.0001
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0004 0.0011 0.0016
Schistosoma mansoni unc-13 (munc13) 0.0007 0.0055 0.0153
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0008 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Loa Loa (eye worm) hypothetical protein 0.0018 0.0185 0.029
Loa Loa (eye worm) hypothetical protein 0.0013 0.0126 0.0197
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0102 0.1225 0.3432
Trypanosoma brucei DNA polymerase kappa, putative 0.0003 0.0004 0.0006
Schistosoma mansoni notch 0.0018 0.0185 0.0519
Echinococcus granulosus dna polymerase kappa 0.0004 0.002 0.005
Brugia malayi Steroid receptor seven-up type 2 0.0065 0.0773 0.121
Loa Loa (eye worm) hypothetical protein 0.0065 0.0773 0.1212
Echinococcus multilocularis neurogenic locus notch protein 4 0.0018 0.0185 0.0185
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0008 0.0064 0.0098
Echinococcus multilocularis protein kinase c iota type 0.0007 0.0051 0.0051
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0004 0.0015 0.0015
Schistosoma mansoni patched 1 0.0011 0.0096 0.027
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Onchocerca volvulus 0.0012 0.012 0.044
Echinococcus granulosus importin subunit beta 1 0.0007 0.0052 0.0128
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0102 0.1225 0.3432
Onchocerca volvulus 0.0065 0.0773 0.2985
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0009 0.0083 0.0957
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.001 0.0085 0.0315
Loa Loa (eye worm) hypothetical protein 0.0004 0.0019 0.0029
Loa Loa (eye worm) hypothetical protein 0.0005 0.0022 0.0034
Echinococcus multilocularis Diacylglycerol kinase theta 0.0007 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0007 0.0049 0.0076
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0031 0.0347 0.0347
Trypanosoma brucei trypanothione reductase 0.0009 0.0083 0.0305
Echinococcus granulosus neuropeptide s receptor 0.0333 0.4083 1
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0191 0.2321 0.8756
Echinococcus multilocularis rhodopsin orphan GPCR 0.0102 0.1225 0.1225
Toxoplasma gondii NADP-dependent succinate-semialdehyde dehydrogenase 0.0003 0.0008 0.0058
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0081 0.0966 0.1513
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0005 0.0029 0.0946
Treponema pallidum gamma-glutamyl phosphate reductase 0.0003 0.0008 0.0138
Onchocerca volvulus 0.0005 0.0022 0.0055
Leishmania major DNA polymerase kappa, putative 0.0004 0.002 0.007
Echinococcus multilocularis ras gtpase 0.0038 0.0439 0.0439
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0102 0.1225 0.3432
Loa Loa (eye worm) hypothetical protein 0.0069 0.0814 0.1276
Echinococcus granulosus protein jagged 1 0.0018 0.0185 0.0453
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0003 0.0002 0.0001
Loa Loa (eye worm) hypothetical protein 0.0022 0.0241 0.0378
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0003 0.0008 0.0021
Entamoeba histolytica hypothetical protein 0.0004 0.0019 0.0161
Echinococcus multilocularis smad 0.0004 0.0015 0.0015
Schistosoma mansoni neuropeptide receptor 0.0102 0.1225 0.3432
Echinococcus multilocularis serotonin receptor 0.0102 0.1225 0.1225
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0005 0.0022 0.0034
Schistosoma mansoni tar DNA-binding protein 0.0016 0.0161 0.0452
Brugia malayi hypothetical protein 0.0004 0.0011 0.0016
Leishmania major hypothetical protein, conserved 0.0068 0.0803 0.3024
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0021 0.0225 0.0351
Echinococcus multilocularis FTZ F1 alpha 0.0065 0.0773 0.0773
Schistosoma mansoni biogenic amine receptor 0.0102 0.1225 0.3432
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0012 0.012 0.0337
Echinococcus multilocularis jun protein 0.0268 0.3284 0.3284
Loa Loa (eye worm) hypothetical protein 0.0437 0.5368 0.8416
Loa Loa (eye worm) hypothetical protein 0.0018 0.0185 0.029
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0003 0.0002 0.0005
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0004 0.0015 0.0015
Onchocerca volvulus 0.0005 0.0022 0.0055
Loa Loa (eye worm) aldehyde dehydrogenase 4 0.0003 0.0008 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0065 0.0773 0.121
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Schistosoma mansoni aldehyde dehydrogenase 0.0003 0.0008 0.0021
Echinococcus granulosus Niemann Pick C1 protein 0.0025 0.027 0.066
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0018 0.0185 0.0288
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0004 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0069 0.0814 0.1276
Brugia malayi hypothetical protein 0.0102 0.1225 0.1919
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Loa Loa (eye worm) RasGEF domain-containing protein 0.0007 0.0049 0.0076
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0005 0.0022 0.0034
Brugia malayi Animal haem peroxidase family protein 0.0069 0.0814 0.1274
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0024 0.0262 0.3206
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0004 0.0013 0.0013
Brugia malayi nuclear hormone receptor 0.0031 0.0347 0.0542
Loa Loa (eye worm) hypothetical protein 0.0008 0.0064 0.01
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0003 0.0008 0.0014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0065 0.0773 0.1212
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0003 0.0002 0.0002
Brugia malayi diacylglycerol kinase 0.0007 0.0049 0.0075
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0003 0.0006 0.0018
Loa Loa (eye worm) MH1 domain-containing protein 0.0004 0.0015 0.0024
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.001 0.0085 0.0085
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0034 0.0392 0.0615
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0008 0.0064 0.0156
Schistosoma mansoni protein-tyrosine phosphatase non-receptor type nt5 0.0005 0.0022 0.0061
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0065 0.0773 0.121
Trypanosoma cruzi DNA polymerase eta, putative 0.0004 0.002 0.007
Entamoeba histolytica 1,4-alpha-glucan branching enzyme, putative 0.0026 0.0292 0.4108
Echinococcus granulosus neuropeptide receptor A26 0.0333 0.4083 1
Brugia malayi MH1 domain containing protein 0.0004 0.0015 0.0022
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0003 0.0002 0.0001
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0005 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0069 0.0814 0.1276
Onchocerca volvulus 0.0005 0.0022 0.0055
Echinococcus multilocularis nuclear receptor nhr 48 0.0031 0.0347 0.0347
Loa Loa (eye worm) neuropeptide F receptor 0.0102 0.1225 0.192
Echinococcus multilocularis cyclic AMP responsive element binding protein 0.0007 0.0057 0.0057
Mycobacterium leprae Putative uncharacterized protein ML2045 0.0007 0.0046 0.1527
Onchocerca volvulus 0.0005 0.0022 0.0055
Brugia malayi hypothetical protein 0.0102 0.1225 0.1919
Brugia malayi putative neuropeptide receptor NPR1 0.0102 0.1225 0.1919
Loa Loa (eye worm) hypothetical protein 0.0018 0.0185 0.029
Loa Loa (eye worm) melatonin receptor type 1A 0.0102 0.1225 0.192
Loa Loa (eye worm) isocitrate dehydrogenase 0.0004 0.0015 0.0023
Schistosoma mansoni ran 0.0005 0.0029 0.0082
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0102 0.1225 0.3432
Onchocerca volvulus 0.0102 0.1225 0.4748
Trichomonas vaginalis alpha-amylase, putative 0.0059 0.07 1
Brugia malayi Serotonin receptor 0.0102 0.1225 0.1919
Loa Loa (eye worm) hypothetical protein 0.0031 0.0347 0.0543
Schistosoma mansoni hypothetical protein 0.0003 0.0001 0.0003
Brugia malayi hypothetical protein 0.0102 0.1225 0.1919
Loa Loa (eye worm) hypothetical protein 0.0004 0.0011 0.0018
Echinococcus granulosus nuclear receptor nhr 48 0.0031 0.0347 0.0849
Loa Loa (eye worm) hypothetical protein 0.0074 0.0879 0.1378
Trypanosoma cruzi squalene synthase, putative 0.0217 0.265 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.027 0.0423
Onchocerca volvulus 4.1 G protein, putative homolog 0.0005 0.0022 0.0055
Loa Loa (eye worm) hypothetical protein 0.0004 0.0011 0.0018
Onchocerca volvulus 0.0026 0.0286 0.1086
Loa Loa (eye worm) animal heme peroxidase 0.0069 0.0814 0.1276
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0024 0.0261 0.0639
Echinococcus multilocularis neuropeptide FF receptor 2 0.0102 0.1225 0.1225
Loa Loa (eye worm) hypothetical protein 0.0018 0.0185 0.029
Toxoplasma gondii kinesin motor domain-containing protein 0.001 0.0091 0.0923
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0012 0.012 0.0337
Trypanosoma cruzi squalene synthase, putative 0.0217 0.265 1
Schistosoma mansoni nAChR subunit 0.0008 0.0064 0.0179
Loa Loa (eye worm) hypothetical protein 0.0007 0.0049 0.0076
Trypanosoma brucei DNA polymerase kappa, putative 0.0004 0.002 0.007
Brugia malayi Protein-tyrosine phosphatase 0.0005 0.0022 0.0032
Loa Loa (eye worm) hypothetical protein 0.0007 0.0049 0.0076
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0003 0.0008 0.0021
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0004 0.002 0.007
Schistosoma mansoni protein kinase C mu 0.0061 0.0717 0.2008
Brugia malayi hypothetical protein 0.0034 0.0392 0.0613
Brugia malayi Succinate semialdehyde dehydrogenase, mitochondrial precursor 0.0003 0.0008 0.001
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0008 0.0064 0.0064
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0007 0.0057 0.0057
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0007 0.0049 0.0049
Echinococcus multilocularis transient receptor potential cation channel 0.0003 0.0001 0.0001
Echinococcus granulosus dna polymerase eta 0.0004 0.002 0.005
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0102 0.1225 0.1225
Loa Loa (eye worm) hypothetical protein 0.0022 0.0238 0.0373
Schistosoma mansoni ankyrin 23/unc44 0.0011 0.01 0.0279
Schistosoma mansoni hypothetical protein 0.0291 0.3568 1
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0102 0.1225 0.2999
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0007 0.0049 0.0136
Schistosoma mansoni notch 0.0018 0.0185 0.0519
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0005 0.0022 0.0053
Echinococcus granulosus neuropeptides capa receptor 0.0102 0.1225 0.2999
Brugia malayi Cation transporter family protein 0.0026 0.0286 0.0447
Echinococcus multilocularis dro:myosuppressin receptor 0.0102 0.1225 0.1225
Toxoplasma gondii EGF family domain-containing protein 0.0018 0.0185 0.19
Loa Loa (eye worm) hypothetical protein 0.0081 0.0966 0.1515
Loa Loa (eye worm) hypothetical protein 0.0031 0.0347 0.0543
Mycobacterium tuberculosis Probable aldehyde dehydrogenase (NAD+) dependent 0.0003 0.0008 0.0014
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0034 0.0392 0.1099
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0005 0.0022 0.0022
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0055 0.065 0.065
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0005 0.0022 0.0053
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0005 0.0022 0.0022
Loa Loa (eye worm) Ras protein let-60 0.0038 0.0439 0.0688
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0024 0.0262 1
Brugia malayi hypothetical protein 0.0004 0.0011 0.0016
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0003 0.0002 0.0003
Loa Loa (eye worm) carboxylesterase 0.0012 0.012 0.0189
Echinococcus multilocularis dna polymerase kappa 0.0004 0.002 0.002
Onchocerca volvulus 0.0005 0.0022 0.0055
Mycobacterium tuberculosis Probable pyrroline-5-carboxylate dehydrogenase RocA 0.0003 0.0008 0.0014
Loa Loa (eye worm) hypothetical protein 0.0074 0.0879 0.1378
Plasmodium vivax glutathione reductase, putative 0.0009 0.0083 0.9069
Loa Loa (eye worm) hypothetical protein 0.0069 0.0814 0.1276
Toxoplasma gondii histone lysine methyltransferase SET1 0.0014 0.0136 0.1395
Mycobacterium ulcerans trehalose synthase TreS 0.0007 0.0046 0.0501
Loa Loa (eye worm) hypothetical protein 0.0007 0.0057 0.0089
Trichomonas vaginalis alpha-amylase, putative 0.0007 0.0046 0.0636
Entamoeba histolytica Ran family GTPase 0.0005 0.0029 0.0315
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0005 0.0022 0.0032
Echinococcus multilocularis sex peptide receptor 0.0102 0.1225 0.1225
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0102 0.1225 0.3432
Schistosoma mansoni atypical protein kinase C 0.0007 0.0051 0.0143
Plasmodium falciparum glutathione reductase 0.0003 0.0006 0.0047
Brugia malayi steroid hormone receptor 0.0065 0.0773 0.121
Loa Loa (eye worm) MH2 domain-containing protein 0.0004 0.0015 0.0024
Echinococcus multilocularis neural cadherin 0.0018 0.0185 0.0185
Loa Loa (eye worm) hypothetical protein 0.0054 0.0631 0.099
Echinococcus granulosus thioredoxin glutathione reductase 0.001 0.0084 0.0206
Loa Loa (eye worm) hypothetical protein 0.0007 0.0049 0.0076
Schistosoma mansoni hypothetical protein 0.0068 0.0803 0.2249
Giardia lamblia 1,4-alpha-glucan branching enzyme 0.0026 0.0292 1
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0008 0.0064 0.0156
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0065 0.0773 0.1892
Schistosoma mansoni biogenic amine receptor 0.0102 0.1225 0.3432
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0022 0.0232 0.2833
Echinococcus granulosus slit 2 protein 0.0018 0.0185 0.0453
Loa Loa (eye worm) hypothetical protein 0.0005 0.0022 0.0034
Trichomonas vaginalis dexras1, putative 0.0038 0.0439 0.6256
Schistosoma mansoni hypothetical protein 0.0004 0.0013 0.0037
Schistosoma mansoni hypothetical protein 0.0102 0.1225 0.3432
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0008 0.0064 0.01
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0011 0.0101 0.0282
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0005 0.0022 0.0061
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0008 0.0064 0.0156
Loa Loa (eye worm) hypothetical protein 0.0003 0.0001 0.0002
Brugia malayi Nuclear hormone receptor-like 1 0.0034 0.0392 0.0613
Entamoeba histolytica deoxycytidyl transferase, putative 0.0004 0.002 0.0186
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0042 0.0491 0.1202
Onchocerca volvulus Peroxidasin homolog 0.0069 0.0814 0.3144
Loa Loa (eye worm) hypothetical protein 0.0004 0.0019 0.0029
Loa Loa (eye worm) hypothetical protein 0.0012 0.012 0.0189
Echinococcus granulosus neurogenic locus notch protein 0.0018 0.0185 0.0453
Loa Loa (eye worm) hypothetical protein 0.0069 0.0814 0.1276
Leishmania major delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0003 0.0008 0.0021
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0005 0.0022 0.0061
Brugia malayi Calcium binding EGF domain containing protein 0.0018 0.0185 0.0288
Loa Loa (eye worm) hypothetical protein 0.0005 0.0022 0.0034
Echinococcus granulosus tar DNA binding protein 0.0016 0.0161 0.0395
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0178 0.2164 0.6065
Schistosoma mansoni nuclear receptor nhr-48 0.0031 0.0347 0.0971
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0008 0.0064 0.0098
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.072 0.2712
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0065 0.0773 0.1212
Loa Loa (eye worm) ACC-1 protein 0.0008 0.0064 0.01
Brugia malayi GCC2 and GCC3 family protein 0.0018 0.0185 0.0288
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0102 0.1225 0.3432
Loa Loa (eye worm) hypothetical protein 0.0004 0.0011 0.0018
Brugia malayi Isocitrate dehydrogenase 0.0004 0.0015 0.0021
Brugia malayi MH2 domain containing protein 0.0004 0.0015 0.0022
Brugia malayi hypothetical protein 0.0069 0.0814 0.1274
Loa Loa (eye worm) hypothetical protein 0.0034 0.0392 0.0615
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0003 0.0002 0.0005
Echinococcus multilocularis dna polymerase eta 0.0004 0.002 0.002
Giardia lamblia NADH oxidase lateral transfer candidate 0.0003 0.0006 0.0157
Echinococcus granulosus protein kinase c epsilon type 0.0007 0.0051 0.0125
Schistosoma mansoni biogenic amine receptor 0.0102 0.1225 0.3432
Onchocerca volvulus 0.0102 0.1225 0.4748
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0027 0.0295 0.3036
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Echinococcus granulosus fos transcription factor 0.0007 0.0057 0.014
Entamoeba histolytica ras-1, putative 0.0038 0.0439 0.6225
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0003 0.0008 0.0021
Brugia malayi follicle stimulating hormone receptor 0.0519 0.6378 1
Echinococcus granulosus BC026374 protein S09 family 0.0012 0.012 0.0294
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0003 0.0002 0.0005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0102 0.1225 0.3432
Echinococcus granulosus FTZ F1 alpha 0.0065 0.0773 0.1892
Loa Loa (eye worm) TAR-binding protein 0.0016 0.0161 0.0253
Brugia malayi hypothetical protein 0.0005 0.0022 0.0032
Echinococcus granulosus glycine receptor subunit alpha 1 0.0008 0.0064 0.0156
Onchocerca volvulus 0.0005 0.0022 0.0055
Onchocerca volvulus 0.0102 0.1225 0.4748
Entamoeba histolytica alpha-amylase family protein 0.0007 0.0046 0.056
Toxoplasma gondii methylmalonate-semialdehyde dehydrogenase [acylating], putative 0.0003 0.0008 0.0058
Giardia lamblia Protein tyrosine phosphatase 0.0005 0.0022 0.0684
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0065 0.0773 0.0773
Mycobacterium tuberculosis Conserved hypothetical protein 0.0004 0.002 0.0175
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0065 0.0773 0.1212
Brugia malayi Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor 0.0003 0.0008 0.001
Schistosoma mansoni notch 0.0018 0.0186 0.0522
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0061 0.0717 0.1122
Echinococcus multilocularis alpha glucosidase 0.0007 0.0046 0.0046
Trichomonas vaginalis alpha-amylase, putative 0.0007 0.0046 0.0636
Brugia malayi hypothetical protein 0.0102 0.1225 0.1919
Trypanosoma brucei importin beta-1 subunit, putative 0.0007 0.0052 0.0189
Brugia malayi Cadherin domain containing protein 0.0018 0.0185 0.0288
Giardia lamblia DINP protein human, muc B family 0.0004 0.002 0.0637
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0005 0.0022 0.0205
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0005 0.0022 0.0053
Onchocerca volvulus Peroxidase homolog 0.0069 0.0814 0.3144
Loa Loa (eye worm) hypothetical protein 0.0081 0.0966 0.1515
Echinococcus multilocularis sodium channel protein 0.0042 0.0491 0.0491
Trypanosoma brucei DNA polymerase kappa, putative 0.0004 0.002 0.007
Loa Loa (eye worm) hypothetical protein 0.0005 0.0022 0.0034
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Trypanosoma cruzi DNA polymerase kappa, putative 0.0004 0.002 0.007
Echinococcus granulosus ras gtpase 0.0038 0.0439 0.1075
Echinococcus granulosus geminin 0.0291 0.3568 0.8738
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0003 0.0008 0.0014
Echinococcus granulosus G protein coupled receptor 139 0.0102 0.1225 0.2999
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0005 0.0022 0.0034
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0411 0.1007
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0005 0.0022 0.0032
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0003 0.0002 0.0005
Trichomonas vaginalis spcc417.12 protein, putative 0.0012 0.012 0.1694
Brugia malayi hypothetical protein 0.0034 0.0392 0.0613
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0005 0.0022 0.0022
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0008 0.0064 0.01
Brugia malayi Cadherin domain containing protein 0.0018 0.0185 0.0288
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0034 0.0392 0.096
Schistosoma mansoni slit 0.0018 0.0185 0.0519
Plasmodium vivax thioredoxin reductase, putative 0.0009 0.0083 0.9069
Mycobacterium ulcerans maltooligosyltrehalose trehalohydrolase, TreZ 0.0007 0.0046 0.0501
Brugia malayi Protein-tyrosine phosphatase 0.0005 0.0022 0.0032
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0005 0.0022 0.0053
Trichomonas vaginalis glutathione reductase, putative 0.0003 0.0006 0.0065
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0008 0.0064 0.0098
Loa Loa (eye worm) hypothetical protein 0.0012 0.012 0.0189
Brugia malayi notch-like transmembrane receptor 0.0018 0.0185 0.0288
Onchocerca volvulus Dual oxidase homolog 0.0069 0.0814 0.3144
Brugia malayi tailless protein 0.0031 0.0347 0.0542
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0004 0.0011 0.0027
Echinococcus granulosus neurogenic locus notch protein 0.0018 0.0185 0.0453
Onchocerca volvulus 0.0102 0.1225 0.4748
Trichomonas vaginalis amylase, putative 0.0007 0.0046 0.0636
Mycobacterium tuberculosis Possible succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD2 0.0003 0.0008 0.0014
Schistosoma mansoni Smad4 0.0004 0.0015 0.0043
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0008 0.0064 0.0064
Schistosoma mansoni hypothetical protein 0.0007 0.0057 0.016
Echinococcus granulosus protein kinase c eta type 0.0007 0.0049 0.0119
Schistosoma mansoni steroid hormone receptor ad4bp 0.0065 0.0773 0.2166
Onchocerca volvulus 0.0005 0.0022 0.0055
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0102 0.1225 0.192
Loa Loa (eye worm) hypothetical protein 0.0031 0.0347 0.0543
Loa Loa (eye worm) G-protein coupled receptor 0.0102 0.1225 0.192
Brugia malayi bZIP transcription factor family protein 0.0007 0.0057 0.0088
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0003 0.0002 0.0005
Schistosoma mansoni septate junction protein 0.0018 0.0185 0.0519
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0003 0.0006 0.0017
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0005 0.0022 0.0034
Echinococcus multilocularis fat cadherin tumor suppressor 0.0018 0.0185 0.0185
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0007 0.0049 0.0076
Brugia malayi ecdysteroid receptor 0.0065 0.0773 0.121
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0005 0.0022 0.0032
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0004 0.0011 0.0016
Brugia malayi conserved hypotetical protein 0.0031 0.0347 0.0542
Trypanosoma cruzi PAB1-binding protein , putative 0.0006 0.0044 0.0158
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0005 0.0022 0.0032
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0102 0.1225 0.1225
Echinococcus granulosus Protein patched homolog 1 0.0011 0.0096 0.0236
Echinococcus granulosus tm gpcr rhodopsin 0.0102 0.1225 0.2999
Echinococcus granulosus cAMP responsive element binding protein 3 0.0007 0.0057 0.014
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0005 0.0022 0.0034
Loa Loa (eye worm) hypothetical protein 0.0012 0.012 0.0189
Loa Loa (eye worm) hypothetical protein 0.0017 0.0176 0.0276
Entamoeba histolytica alpha-amylase, putative 0.0007 0.0046 0.056
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0102 0.1225 0.3432
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0005 0.0022 0.0053
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0003 0.0006 0.0017
Schistosoma mansoni hypothetical protein 0.0018 0.0185 0.0519
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0007 0.0057 0.014
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0005 0.0022 0.0032
Onchocerca volvulus 0.0004 0.0019 0.0044
Onchocerca volvulus 0.0062 0.0736 0.2843
Brugia malayi EGF-like domain containing protein 0.0018 0.0185 0.0288
Schistosoma mansoni aldehyde dehydrogenase 0.0003 0.0008 0.0021
Onchocerca volvulus 0.0004 0.0019 0.0044
Leishmania major trypanothione reductase 0.0009 0.0083 0.0305
Plasmodium falciparum thioredoxin reductase 0.0003 0.0006 0.0047
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0178 0.2164 0.3392
Brugia malayi C1-like domain containing protein 0.0061 0.0717 0.1122
Loa Loa (eye worm) animal heme peroxidase 0.0069 0.0814 0.1276
Schistosoma mansoni amine GPCR 0.0102 0.1225 0.3432
Echinococcus multilocularis g protein coupled receptor 0.0102 0.1225 0.1225
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0102 0.1225 0.2999
Onchocerca volvulus 0.0005 0.0022 0.0055
Brugia malayi Alpha amylase, catalytic domain containing protein 0.0007 0.0046 0.0071
Mycobacterium tuberculosis Probable glucanase GlgE 0.0007 0.0046 0.0501
Brugia malayi hypothetical protein 0.0211 0.2571 0.403
Onchocerca volvulus 0.0005 0.0022 0.0055
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0003 0.0008 0.0021
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0003 0.0006 0.0006
Echinococcus multilocularis geminin 0.0291 0.3568 0.3568
Brugia malayi Kinesin motor domain containing protein 0.001 0.0091 0.0141
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0004 0.0015 0.0048
Echinococcus granulosus N chimaerin 0.0007 0.0049 0.0119
Schistosoma mansoni neurotransmitter gated ion channel 0.0004 0.0011 0.0031
Loa Loa (eye worm) hypothetical protein 0.0031 0.0347 0.0543
Onchocerca volvulus Peroxidase homolog 0.0069 0.0814 0.3144
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0005 0.0022 0.0022
Schistosoma mansoni diacylglycerol kinase theta 0.0007 0.0049 0.0136
Loa Loa (eye worm) animal heme peroxidase 0.0069 0.0814 0.1276
Schistosoma mansoni camp-response element binding protein-related 0.0007 0.0057 0.016
Brugia malayi EGF-like domain containing protein 0.0018 0.0185 0.0288
Mycobacterium ulcerans bifunctional acetaldehyde-CoA/alcohol dehydrogenase 0.0003 0.0008 0.0014
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0007 0.0051 0.0051
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0008 0.0064 0.01
Echinococcus multilocularis Fatty aldehyde dehydrogenase 0.0003 0.0008 0.0008
Echinococcus granulosus g protein coupled receptor 0.0102 0.1225 0.2999
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0008 0.0064 0.0098
Brugia malayi bZIP transcription factor family protein 0.0268 0.3284 0.5147
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0004 0.0011 0.0016
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0041 0.0471 0.0471
Echinococcus granulosus orexin receptor type 2 0.0102 0.1225 0.2999
Schistosoma mansoni hypothetical protein 0.001 0.0092 0.0257
Loa Loa (eye worm) hypothetical protein 0.0018 0.0185 0.029
Trypanosoma brucei DNA polymerase kappa, putative 0.0004 0.002 0.007
Echinococcus multilocularis Rac GTPase activating protein 1 0.0007 0.0049 0.0049
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0003 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0261 0.3193 0.5006
Brugia malayi RNA binding protein 0.0016 0.0161 0.0251
Echinococcus granulosus rhodopsin orphan GPCR 0.0102 0.1225 0.2999
Onchocerca volvulus 0.0004 0.0011 0.0014
Onchocerca volvulus 0.0005 0.0022 0.0055
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0005 0.0022 0.0053
Trypanosoma cruzi importin beta-1 subunit, putative 0.0006 0.0036 0.0128
Trypanosoma cruzi phytoene synthase, putative 0.0068 0.0803 0.3024
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0003 0.0006 0.0017
Brugia malayi AKH receptor 0.0102 0.1225 0.1919
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0102 0.1225 0.1919
Brugia malayi hypothetical protein 0.0004 0.0011 0.0016
Onchocerca volvulus 0.0012 0.012 0.044
Schistosoma mansoni non-receptor protein-tyrosine phosphatase 0.0005 0.0022 0.0061
Echinococcus multilocularis betaine aldehyde dehydrogenase 0.0003 0.0008 0.0008
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0004 0.0011 0.0016
Schistosoma mansoni hypothetical protein 0.0017 0.0176 0.0493
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0005 0.0022 0.0034
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0017 0.0176 0.0274
Schistosoma mansoni opsin-like receptor 0.0102 0.1225 0.3432
Echinococcus granulosus tm gpcr rhodopsin 0.0102 0.1225 0.2999
Brugia malayi nuclear receptor RXR 0.0034 0.0392 0.0613
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0005 0.0022 0.0061
Mycobacterium ulcerans aldehyde dehydrogenase 0.0003 0.0008 0.0014
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0008 0.0064 0.0156
Schistosoma mansoni rgs-gaip interacting protein gipc 0.0005 0.0022 0.0061
Brugia malayi Dual specificity protein phosphatase CDC14B 0.0005 0.0022 0.0032
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0007 0.0049 0.0119
Loa Loa (eye worm) hypothetical protein 0.0034 0.0392 0.0615
Onchocerca volvulus 0.0005 0.0022 0.0055
Schistosoma mansoni succinate semialdehyde dehydrogenase 0.0003 0.0008 0.0021
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0006 0.0036 0.0485
Brugia malayi hypothetical protein 0.0031 0.0347 0.0542
Schistosoma mansoni hypothetical protein 0.0004 0.0013 0.0037
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0003 0.0006 0.0017
Echinococcus multilocularis raf serine:threonine protein kinase 0.0007 0.0049 0.0049
Schistosoma mansoni hypothetical protein 0.0018 0.0185 0.0519
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0003 0.0008 0.0021
Entamoeba histolytica Ras family GTPase 0.0038 0.0439 0.6225
Echinococcus granulosus neurogenic locus protein delta 0.0018 0.0185 0.0453
Onchocerca volvulus 0.0008 0.0064 0.022
Loa Loa (eye worm) hypothetical protein 0.0031 0.0347 0.0543
Loa Loa (eye worm) hypothetical protein 0.0065 0.0773 0.1212
Loa Loa (eye worm) hypothetical protein 0.0008 0.0068 0.0106
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0006 0.0036 0.0352
Loa Loa (eye worm) Smad1 0.0004 0.0015 0.0024
Plasmodium falciparum glutathione reductase 0.0009 0.0083 0.0837
Echinococcus multilocularis Niemann Pick C1 protein 0.0025 0.027 0.027
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Loa Loa (eye worm) hypothetical protein 0.0062 0.0736 0.1155
Onchocerca volvulus 0.0018 0.0185 0.0693
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.001 0.0085 0.0315
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0031 0.0347 0.0971
Loa Loa (eye worm) hypothetical protein 0.0004 0.0019 0.0029
Schistosoma mansoni camp-response element binding protein-related 0.0007 0.0057 0.016
Brugia malayi Pleckstrin Homology Domain 0.0008 0.0071 0.011
Echinococcus granulosus fmrfamide receptor 0.0102 0.1225 0.2999
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0081 0.0966 0.1513
Schistosoma mansoni hypothetical protein 0.0218 0.2662 0.7461
Brugia malayi Serotonin receptor 0.0102 0.1225 0.1919
Onchocerca volvulus 0.0038 0.0432 0.1655
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0003 0.0008 0.0008
Mycobacterium ulcerans maltooligosyltrehalose synthase TreX 0.0007 0.0046 0.0501
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0031 0.0347 0.0347
Echinococcus multilocularis mothers against decapentaplegic 5 0.0004 0.0015 0.0015
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0042 0.0491 0.1845
Echinococcus multilocularis kinesin family 1 0.0078 0.0928 0.0928
Loa Loa (eye worm) hypothetical protein 0.0004 0.0013 0.0021
Echinococcus multilocularis G protein coupled receptor 139 0.0102 0.1225 0.1225
Mycobacterium tuberculosis Probable aldehyde dehydrogenase AldC 0.0003 0.0008 0.0014
Loa Loa (eye worm) hypothetical protein 0.0004 0.0011 0.0018
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0065 0.0773 0.2166
Brugia malayi hypothetical protein 0.0004 0.0016 0.0024
Loa Loa (eye worm) acetylcholine receptor protein 0.0004 0.0011 0.0018
Loa Loa (eye worm) hypothetical protein 0.0018 0.0185 0.029
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0005 0.0022 0.0061
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0004 0.0011 0.0011
Brugia malayi hypothetical protein 0.0038 0.0432 0.0676
Schistosoma mansoni protein tyrosine phosphatase 0.0005 0.0022 0.0061
Echinococcus multilocularis short transient receptor potential channel 6 0.0003 0.0001 0.0001
Brugia malayi sulfakinin receptor protein 0.0102 0.1225 0.1919
Schistosoma mansoni hypothetical protein 0.0104 0.1247 0.3494
Schistosoma mansoni smad1 5 8 and 0.0004 0.0015 0.0043
Trypanosoma brucei DNA polymerase kappa, putative 0.0004 0.002 0.007
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0081 0.0966 0.1515
Loa Loa (eye worm) hypothetical protein 0.0011 0.0101 0.0158
Onchocerca volvulus 0.0211 0.2571 1
Echinococcus granulosus myotubularin protein 13 0.0008 0.0071 0.0174
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0005 0.0029 0.0044
Echinococcus multilocularis g protein coupled receptor 0.0102 0.1225 0.1225
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0008 0.0064 0.0156
Brugia malayi hypothetical protein 0.0102 0.1225 0.1919
Mycobacterium ulcerans aldehyde dehydrogenase (NAD+) dependent 0.0003 0.0008 0.0014
Loa Loa (eye worm) hypothetical protein 0.0004 0.0011 0.0018
Echinococcus multilocularis snurportin 1 0.0074 0.0885 0.0885
Entamoeba histolytica hypothetical protein 0.0006 0.0036 0.0408
Echinococcus multilocularis Squalene phytoene synthase 0.0068 0.0803 0.0803
Loa Loa (eye worm) hypothetical protein 0.0004 0.0011 0.0018
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0005 0.0022 0.0034
Schistosoma mansoni hypothetical protein 0.0018 0.0185 0.0519
Loa Loa (eye worm) hypothetical protein 0.0026 0.0286 0.0448
Entamoeba histolytica alpha-amylase family protein 0.0059 0.07 1
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Onchocerca volvulus 0.0018 0.0185 0.0693
Echinococcus granulosus succinate semialdehyde dehydrogenase 0.0003 0.0008 0.0019
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0031 0.0347 0.1322
Giardia lamblia Alcohol dehydrogenase 0.0003 0.0008 0.0194
Loa Loa (eye worm) hypothetical protein 0.0005 0.0022 0.0034
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0004 0.0019 0.0028
Schistosoma mansoni carbonic anhydrase-related 0.0081 0.0966 0.2708
Schistosoma mansoni protein kinase C mu 0.0007 0.0049 0.0136
Loa Loa (eye worm) hypothetical protein 0.0031 0.0347 0.0543
Toxoplasma gondii diacylglycerol kinase, putative 0.0007 0.0049 0.0484
Echinococcus granulosus sodium channel protein 0.0042 0.0491 0.1202
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0065 0.0773 0.2166
Echinococcus granulosus Niemann Pick C1 protein 0.0035 0.04 0.0979
Brugia malayi Carboxylesterase family protein 0.0012 0.012 0.0187
Echinococcus granulosus Nuclear hormone receptor HR96 0.0031 0.0347 0.0849
Loa Loa (eye worm) hypothetical protein 0.0069 0.0814 0.1276
Echinococcus granulosus betaine aldehyde dehydrogenase 0.0003 0.0008 0.0019
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0347 0.0849
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0102 0.1225 0.2999
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0005 0.0022 0.0032
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0003 0.0008 0.0021
Brugia malayi Latrophilin receptor protein 2 0.0004 0.0013 0.0019
Brugia malayi Melatonin receptor type 1A 0.0102 0.1225 0.1919
Brugia malayi 1,4-alpha-glucan branching enzyme 0.0026 0.0292 0.0456
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0004 0.0015 0.0048
Trichomonas vaginalis amylase, putative 0.0026 0.0292 0.4155
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.072 0.2019
Loa Loa (eye worm) hypothetical protein 0.0012 0.012 0.0189
Echinococcus multilocularis allatostatin A receptor 0.0102 0.1225 0.1225
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0026 0.0286 0.0801
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0008 0.0064 0.0064
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0003 0.0001 0.0001
Toxoplasma gondii gamma-glutamyl phosphate reductase, putative 0.0003 0.0008 0.0058
Echinococcus multilocularis g protein coupled receptor 0.0102 0.1225 0.1225
Brugia malayi glutathione reductase 0.0009 0.0083 0.0128
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0065 0.0773 0.1212
Loa Loa (eye worm) hypothetical protein 0.0004 0.0011 0.0018
Loa Loa (eye worm) hypothetical protein 0.0005 0.0022 0.0034
Echinococcus granulosus serotonin receptor 0.0102 0.1225 0.2999
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0065 0.0773 0.1892
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0003 0.0006 0.0047
Loa Loa (eye worm) hypothetical protein 0.0008 0.0071 0.0111
Loa Loa (eye worm) hypothetical protein 0.0007 0.0049 0.0076
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0004 0.002 0.0057
Schistosoma mansoni cell polarity protein 0.0018 0.0185 0.0519
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0003 0.0006 0.0017
Echinococcus multilocularis carboxylesterase 5A 0.0074 0.0879 0.0879
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0005 0.0022 0.0034
Schistosoma mansoni hypothetical protein 0.0102 0.1225 0.3432
Loa Loa (eye worm) hypothetical protein 0.0031 0.0347 0.0543
Toxoplasma gondii glycosyltransferase 0.0026 0.0292 0.301
Trypanosoma brucei squalene synthase, putative 0.0217 0.265 1
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0007 0.0051 0.0125
Toxoplasma gondii isocitrate dehydrogenase 0.0004 0.0015 0.0133
Loa Loa (eye worm) hypothetical protein 0.0012 0.012 0.0189
Mycobacterium ulcerans methylmalonate semialdehyde dehydrogenase, MmsA 0.0003 0.0008 0.0014
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0012 0.012 0.1429
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0005 0.0022 0.0034
Brugia malayi hypothetical protein 0.0102 0.1225 0.1919
Entamoeba histolytica beta/alpha-amylase precursor, putative 0.0007 0.0046 0.056
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0007 0.0049 0.0076
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0004 0.0011 0.0016
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0004 0.0013 0.0032
Mycobacterium ulcerans maltooligosyltrehalose synthase TreY 0.0007 0.0046 0.0501
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0004 0.0015 0.0015
Schistosoma mansoni peroxidasin 0.0069 0.0814 0.228
Brugia malayi Nuclear hormone receptor-like 1 0.0065 0.0773 0.121
Schistosoma mansoni delta 1-pyrroline-5-carboxylate synthetase 0.0003 0.0008 0.0021
Trichomonas vaginalis alpha-amylase, putative 0.0059 0.07 1
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0005 0.0022 0.0053
Loa Loa (eye worm) hypothetical protein 0.0003 0.0002 0.0003
Brugia malayi Dopamine receptor 0.0102 0.1225 0.1919
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0102 0.1225 0.1225
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0021 0.0225 0.0551
Echinococcus granulosus netrin receptor unc 5 0.0011 0.01 0.0244
Echinococcus multilocularis serotonin receptor 0.0102 0.1225 0.1225
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0003 0.0002 0.0005
Schistosoma mansoni hypothetical protein 0.0018 0.0185 0.0519
Mycobacterium ulcerans pyrroline-5-carboxylate dehydrogenase, RocA 0.0003 0.0008 0.0014
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.072 0.1764
Brugia malayi aldehyde dehydrogenase 0.0003 0.0008 0.001
Loa Loa (eye worm) hypothetical protein 0.0034 0.0392 0.0615
Onchocerca volvulus 0.0102 0.1225 0.4748
Onchocerca volvulus 0.0102 0.1225 0.4748
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0003 0.0008 0.0014
Schistosoma mansoni serine/threonine protein kinase 0.0007 0.0051 0.0143
Echinococcus multilocularis protein jagged 1 0.0018 0.0185 0.0185
Brugia malayi putative neuropeptide receptor 0.0102 0.1225 0.1919
Schistosoma mansoni amine GPCR 0.0102 0.1225 0.3432
Trypanosoma cruzi squalene monooxygenase, putative 0.0197 0.2405 0.9075
Brugia malayi Ras protein let-60 0.0038 0.0439 0.0686
Schistosoma mansoni hypothetical protein 0.0036 0.0411 0.1152
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Loa Loa (eye worm) hypothetical protein 0.0102 0.1225 0.192
Brugia malayi Dopamine receptor protein 2 0.0102 0.1225 0.1919
Echinococcus granulosus carboxylesterase 5A 0.0074 0.0879 0.2152
Schistosoma mansoni neuropeptide receptor 0.0102 0.1225 0.3432
Leishmania major GTP-binding protein, putative 0.0005 0.0029 0.0104
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0003 0.0006 0.0017
Plasmodium falciparum ataxin-2 like protein, putative 0.0006 0.0044 0.0434
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0031 0.0347 0.0971
Loa Loa (eye worm) hypothetical protein 0.0069 0.0814 0.1276
Echinococcus granulosus protein tyrosine phosphatase n9 0.0005 0.0022 0.0053
Onchocerca volvulus 0.0005 0.0022 0.0055
Loa Loa (eye worm) alpha amylase 0.0007 0.0046 0.0073
Brugia malayi Thioredoxin reductase 0.0009 0.0083 0.0128
Onchocerca volvulus 0.0018 0.0185 0.0693
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0012 0.012 0.1429
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0005 0.0022 0.0053
Schistosoma mansoni tar DNA-binding protein 0.0016 0.0161 0.0452
Schistosoma mansoni aldehyde dehydrogenase 0.0003 0.0008 0.0021
Schistosoma mansoni growth hormone secretagogue receptor 0.0102 0.1225 0.3432
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0005 0.0022 0.0032
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0008 0.0064 0.01
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0573 0.0896
Loa Loa (eye worm) bZIP transcription factor family protein 0.0007 0.0057 0.0089
Schistosoma mansoni cpg binding protein 0.0008 0.0061 0.0171

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) > 5000 nM Agonistic activity against PPAR (peroxisome proliferator activated receptor gamma) in Suarus chinesis ChEMBL. 14695833
EC50 (functional) > 5000 nM Agonistic activity against PPAR (peroxisome proliferator activated receptor gamma) in Suarus chinesis ChEMBL. 14695833

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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