Detailed information for compound 315218

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 371.475 | Formula: C24H25N3O
  • H donors: 2 H acceptors: 1 LogP: 4.27 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CNC1CCN(C1)c1ccc(cc1)NC(=O)c1ccc(cc1)c1ccccc1
  • InChi: 1S/C24H25N3O/c1-25-22-15-16-27(17-22)23-13-11-21(12-14-23)26-24(28)20-9-7-19(8-10-20)18-5-3-2-4-6-18/h2-14,22,25H,15-17H2,1H3,(H,26,28)
  • InChiKey: LBHJZTQANJXNGX-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens melanin-concentrating hormone receptor 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0035 0.0012 0.0012
Entamoeba histolytica calpain family cysteine protease, putative 0.0373 0.0794 0.2566
Loa Loa (eye worm) hypothetical protein 0.004 0.0025 0.0025
Schistosoma mansoni centrin 0.0204 0.0404 0.0404
Schistosoma mansoni rab 0.0204 0.0404 0.0404
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial precursor, putative 0.0153 0.0285 0.088
Onchocerca volvulus 0.0052 0.0053 0.011
Brugia malayi proteasome subunit beta type 1 0.0067 0.0088 0.0088
Echinococcus multilocularis transfer RNA-Ile 0.0323 0.0679 0.0679
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4357 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0351 0.0743 0.206
Toxoplasma gondii prolyl endopeptidase 0.165 0.3745 1
Leishmania major i/6 autoantigen-like protein 0.0204 0.0404 0.1058
Trypanosoma brucei metacaspase MCA3 0.0722 0.1601 0.4262
Echinococcus multilocularis calpain 5 0.126 0.2844 0.2844
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1343 0.3036 0.842
Loa Loa (eye worm) calpain family protein 1 0.3356 0.7685 0.7685
Brugia malayi Papain family cysteine protease containing protein 0.0351 0.0743 0.0743
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0117 0.0202 0.0202
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0067 0.0088 0.0088
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0056 0.0061 0.0141
Loa Loa (eye worm) hypothetical protein 0.0032 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0051 0.005 0.005
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0042 0.0029 0.0079
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0937 0.2097 0.5814
Brugia malayi EF hand family protein 0.0204 0.0404 0.0404
Schistosoma mansoni aldo-keto reductase 0.0092 0.0145 0.0145
Giardia lamblia Hypothetical protein 0.0208 0.0413 0.1073
Trypanosoma cruzi Aph-1 protein, putative 0.0096 0.0154 0.0145
Trypanosoma cruzi cysteine peptidase, putative 0.1343 0.3036 0.303
Brugia malayi Blistered cuticle protein 3 0.0168 0.032 0.032
Entamoeba histolytica hypothetical protein 0.004 0.0025 0.0017
Entamoeba histolytica hypothetical protein 0.0072 0.0099 0.0264
Echinococcus multilocularis Protein lozenge 0.0059 0.0067 0.0067
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0373 0.0794 0.2102
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.126 0.2844 0.2838
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0673 0.1486 0.3955
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0198 0.0388 0.0388
Echinococcus multilocularis hypothetical protein 0.126 0.2844 0.2844
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1442 0.3264 0.8713
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0204 0.0404 0.0396
Brugia malayi Cathepsin L-like precursor 0.1343 0.3036 0.3036
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0673 0.1486 0.4499
Trichomonas vaginalis deoxyuridine 5'-triphosphate nucleotidohydrolase, putative 0.0153 0.0285 0.079
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0032 0.0006 0.0006
Trypanosoma cruzi oligopeptidase b 0.0673 0.1486 0.1479
Trypanosoma brucei centrin, putative 0.0204 0.0404 0.106
Schistosoma mansoni cathepsin F (C01 family) 0.0937 0.2097 0.2097
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0117 0.0202 0.0202
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0042 0.0029 0.0029
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1343 0.3036 0.842
Onchocerca volvulus Peroxidase homolog 0.0168 0.032 0.067
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0089 0.0137 0.0137
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0067 0.0088 0.0289
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0373 0.0794 0.0786
Schistosoma mansoni neuronal calcium sensor 0.0204 0.0404 0.0404
Entamoeba histolytica glycogen phosphorylase, putative 0.0106 0.0177 0.0523
Echinococcus granulosus cathepsin l1 0.0937 0.2097 0.2097
Leishmania major prostaglandin f synthase, putative 0.0092 0.0145 0.0364
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1343 0.3036 0.842
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.1833 0.4167 0.4167
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0077 0.0111 0.0111
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0373 0.0794 0.2101
Entamoeba histolytica aldose reductase, putative 0.0092 0.0145 0.0415
Schistosoma mansoni glycogen phosphorylase 0.0106 0.0177 0.0177
Loa Loa (eye worm) hypothetical protein 0.0105 0.0174 0.0174
Leishmania major calcineurin B subunit, putative 0.0204 0.0404 0.1058
Brugia malayi hypothetical protein 0.0089 0.0137 0.0137
Trichomonas vaginalis calpain, putative 0.0373 0.0794 0.2201
Schistosoma mansoni ap endonuclease 0.0056 0.0061 0.0061
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0025 0.0025
Schistosoma mansoni mitochondrial solute carrier 0.0204 0.0404 0.0404
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0065 0.0082 0.0196
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.002 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0722 0.1601 0.4439
Trypanosoma brucei aldo-keto reductase, putative 0.0092 0.0145 0.0366
Toxoplasma gondii melibiase subfamily protein 0.0117 0.0202 0.054
Echinococcus granulosus microtubule associated protein 2 0.1446 0.3272 0.3272
Schistosoma mansoni calmodulin 0.0204 0.0404 0.0404
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0087 0.0133 0.0333
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1343 0.3036 0.842
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.007 0.0093 0.0243
Schistosoma mansoni hypothetical protein 0.0818 0.1822 0.1822
Mycobacterium ulcerans beta-lactamase 0.0035 0.0012 0.0025
Echinococcus multilocularis caspase 2 0.1143 0.2574 0.2574
Leishmania major calpain protease-like protein 0.0373 0.0794 0.2101
Trypanosoma cruzi cruzipain precursor, putative 0.0407 0.0872 0.0864
Entamoeba histolytica cysteine protease, putative 0.0351 0.0743 0.2397
Brugia malayi Trypsin family protein 0.0077 0.0111 0.0111
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0042 0.0029 0.0079
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0373 0.0794 0.2102
Brugia malayi Trypsin-like protease protein 5 0.0077 0.0111 0.0111
Trypanosoma brucei Component of motile flagella 41 0.0204 0.0404 0.106
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.4357 1 1
Echinococcus multilocularis neuronal calcium sensor 0.0204 0.0404 0.0404
Plasmodium falciparum calpain 0.0373 0.0794 0.2614
Brugia malayi proteasome subunit beta type 2 0.0042 0.0029 0.0029
Brugia malayi prolyl oligopeptidase family protein 0.0198 0.0388 0.0388
Schistosoma mansoni cercarial elastase (S01 family) 0.0077 0.0111 0.0111
Loa Loa (eye worm) programmed cell death protein 6 0.0208 0.0413 0.0413
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0042 0.0029 0.0029
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0006 0.0006
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0042 0.0029 0.002
Giardia lamblia Cathepsin L-like protease 0.0351 0.0743 0.1997
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0673 0.1486 1
Brugia malayi PXA domain containing protein 0.004 0.0025 0.0025
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0204 0.0404 0.0404
Schistosoma mansoni NADH-ubiquinone oxidoreductase 0.0072 0.0099 0.0099
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0012 0.0012
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0373 0.0794 0.2101
Schistosoma mansoni cathepsin D (A01 family) 0.0123 0.0215 0.0215
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0056 0.0061 0.0136
Trypanosoma brucei Aph-1 protein, putative 0.0096 0.0154 0.039
Entamoeba histolytica hypothetical protein, conserved 0.0208 0.0413 0.1302
Schistosoma mansoni hypothetical protein 0.0077 0.0111 0.0111
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0012 0.0034
Echinococcus multilocularis Glycosyl transferase, family 35 0.0106 0.0177 0.0177
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0042 0.0029 0.0029
Schistosoma mansoni coup transcription factor 0.0032 0.0006 0.0006
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0204 0.0404 0.0396
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0722 0.1601 0.4439
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0077 0.0111 0.0111
Schistosoma mansoni peroxidasin 0.0168 0.032 0.032
Leishmania major phospholipase c-like protein 0.0204 0.0404 0.1058
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial precursor, putative 0.0153 0.0285 0.088
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0722 0.1601 0.4439
Loa Loa (eye worm) hypothetical protein 0.0351 0.0743 0.0743
Trypanosoma cruzi metacaspase, putative 0.0722 0.1601 0.1593
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0351 0.0743 0.2446
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0373 0.0794 0.2201
Trypanosoma brucei calpain, putative 0.0373 0.0794 0.2102
Toxoplasma gondii preprocathepsin c precursor, putative 0.0351 0.0743 0.1984
Loa Loa (eye worm) hypothetical protein 0.0351 0.0743 0.0743
Echinococcus multilocularis neurocalcin 0.0204 0.0404 0.0404
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0407 0.0872 0.0872
Brugia malayi regulator of G-protein signaling egl-10 0.004 0.0025 0.0025
Onchocerca volvulus Dual oxidase homolog 0.0168 0.032 0.067
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0204 0.0404 0.0404
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1343 0.3036 0.842
Mycobacterium leprae PROBABLE DEOXYCYTIDINE TRIPHOSPHATE DEAMINASE DCD (DCTP DEAMINASE) 0.0053 0.0055 0.0286
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0092 0.0145 0.0145
Trichomonas vaginalis aldo-keto reductase, putative 0.0092 0.0145 0.0401
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0087 0.0133 0.0124
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0722 0.1601 0.4275
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0065 0.0082 0.0496
Onchocerca volvulus 0.0204 0.0404 0.0846
Trypanosoma brucei centrin, putative 0.0204 0.0404 0.106
Trypanosoma brucei calpain-like protein, putative 0.126 0.2844 0.759
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0351 0.0743 0.0743
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0077 0.0111 0.0111
Giardia lamblia Deoxyguanosine kinase/deoxyadenosine kinase subunit, putative 0.0072 0.0099 0.0197
Echinococcus granulosus aldo keto reductase 0.0092 0.0145 0.0145
Onchocerca volvulus Cathepsin F homolog 0.1343 0.3036 0.6361
Loa Loa (eye worm) cytochrome P450 family protein 0.0055 0.0059 0.0059
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0012 0.0012
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0087 0.0133 0.0291
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.0061 0.0169
Echinococcus multilocularis calpain family protein 1, d 0.2468 0.5635 0.5635
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0067 0.0088 0.0244
Schistosoma mansoni cercarial elastase (S01 family) 0.0077 0.0111 0.0111
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0087 0.0133 0.0368
Loa Loa (eye worm) PXA domain-containing protein 0.004 0.0025 0.0025
Leishmania major thymidine kinase, putative 0.0257 0.0526 0.1384
Giardia lamblia Cathepsin B precursor 0.159 0.3606 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0373 0.0794 0.2102
Onchocerca volvulus 0.1343 0.3036 0.6361
Loa Loa (eye worm) hypothetical protein 0.0407 0.0872 0.0872
Entamoeba histolytica cysteine protease, putative 0.0758 0.1682 0.5512
Loa Loa (eye worm) hypothetical protein 0.004 0.0025 0.0025
Schistosoma mansoni alzheimer's disease beta-amyloid related 0.0353 0.0748 0.0748
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0032 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0168 0.032 0.032
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0065 0.0082 0.0082
Onchocerca volvulus 0.0168 0.032 0.067
Trypanosoma cruzi major cysteine proteinase, putative 0.0351 0.0743 0.0735
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0092 0.0145 0.0364
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0079 0.0079
Loa Loa (eye worm) EF hand family protein 0.0204 0.0404 0.0404
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1343 0.3036 0.3036
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0722 0.1601 0.4275
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0078 0.0112 0.0311
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0286 0.0593 0.1565
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0056 0.0061 0.014
Trypanosoma cruzi metacaspase 5, putative 0.0722 0.1601 0.1593
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.002 0.002
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0198 0.0388 0.1077
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.126 0.2844 0.2838
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0351 0.0743 0.2446
Echinococcus granulosus regulator of G protein signaling 7 0.004 0.0025 0.0025
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0056 0.0062 0.0062
Brugia malayi gamma-secretase subunit aph-1 0.0246 0.0502 0.0502
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0056 0.0061 0.0052
Trichomonas vaginalis calmodulin, putative 0.0208 0.0413 0.1144
Schistosoma mansoni reticulocalbin 0.0208 0.0413 0.0413
Mycobacterium ulcerans deoxyuridine 5'-triphosphate nucleotidohydrolase 0.0053 0.0055 0.0311
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.007 0.0093 0.0093
Trichomonas vaginalis calpain, putative 0.0373 0.0794 0.2201
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0351 0.0743 0.206
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0351 0.0743 0.206
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0373 0.0794 0.2101
Loa Loa (eye worm) DEAH box polypeptide 35 0.0105 0.0174 0.0174
Schistosoma mansoni pol-related 0.0092 0.0145 0.0145
Mycobacterium ulcerans hypothetical protein 0.0035 0.0012 0.0025
Entamoeba histolytica hypothetical protein 0.0072 0.0099 0.0264
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0032 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.004 0.0025 0.0025
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0351 0.0743 0.2446
Onchocerca volvulus Cathepsin L homolog 0.1343 0.3036 0.6361
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0067 0.0088 0.0235
Onchocerca volvulus Cell death protein 3 homolog 0.1143 0.2574 0.5393
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0067 0.0088 0.0079
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.004 0.0025 0.0025
Trypanosoma cruzi cruzipain precursor, putative 0.1442 0.3264 0.3258
Onchocerca volvulus 0.0035 0.0012 0.0026
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0137 0.0137
Toxoplasma gondii centrin, putative 0.0204 0.0404 0.1079
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0092 0.0145 0.0401
Schistosoma mansoni regulator of G protein signaling 0.004 0.0025 0.0025
Mycobacterium tuberculosis Probable deoxycytidine triphosphate deaminase Dcd (dCTP deaminase) 0.0053 0.0055 0.0129
Schistosoma mansoni neuronal calcium sensor 0.0204 0.0404 0.0404
Onchocerca volvulus 0.0092 0.0145 0.0303
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.165 0.3745 0.3745
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0351 0.0743 0.206
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0042 0.0029 0.0055
Echinococcus multilocularis EF hand domain containing family member A2 0.0204 0.0404 0.0404
Onchocerca volvulus Protein ultraspiracle homolog 0.0032 0.0006 0.0012
Giardia lamblia Hypothetical protein 0.0072 0.0099 0.0197
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0407 0.0872 0.0872
Echinococcus granulosus cathepsin L 0.0758 0.1682 0.1682
Loa Loa (eye worm) hypothetical protein 0.0035 0.0012 0.0012
Plasmodium falciparum cysteine proteinase falcipain 3 0.1343 0.3036 1
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0373 0.0794 0.2201
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1343 0.3036 0.842
Trichomonas vaginalis conserved hypothetical protein 0.0722 0.1601 0.4439
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0286 0.0593 0.0585
Giardia lamblia Cysteine protease 0.0351 0.0743 0.1997
Loa Loa (eye worm) cathepsin B 0.159 0.3606 0.3606
Plasmodium vivax centrin-1, putative 0.0204 0.0404 0.1331
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0286 0.0593 0.0593
Loa Loa (eye worm) glycogen phosphorylase 0.0106 0.0177 0.0177
Loa Loa (eye worm) animal heme peroxidase 0.0168 0.032 0.032
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0351 0.0743 0.2446
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1442 0.3264 0.8713
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0065 0.0082 0.0496
Schistosoma mansoni cercarial elastase (S01 family) 0.0077 0.0111 0.0111
Echinococcus granulosus prolyl endopeptidase 0.165 0.3745 0.3745
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1343 0.3036 0.842
Giardia lamblia Cathepsin L precursor 0.0351 0.0743 0.1997
Giardia lamblia Glycogen phosphorylase 0.0106 0.0177 0.0416
Giardia lamblia Cathepsin L precursor 0.0351 0.0743 0.1997
Schistosoma mansoni regulator of G protein signaling 0.004 0.0025 0.0025
Toxoplasma gondii cathepsin CPC2 0.0351 0.0743 0.1984
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0078 0.0112 0.0112
Schistosoma mansoni gamma-secretase subunit aph-1 0.0246 0.0502 0.0502
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0378 0.0806 0.0806
Loa Loa (eye worm) hypothetical protein 0.0168 0.032 0.032
Plasmodium vivax importin-beta 2, putative 0.0033 0.0008 0.0027
Echinococcus multilocularis regulator of G protein signaling 3 0.004 0.0025 0.0025
Trypanosoma cruzi calpain cysteine peptidase, putative 0.126 0.2844 0.2838
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0092 0.0145 0.0145
Echinococcus granulosus calmodulin 0.0204 0.0404 0.0404
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.0006 0.0006
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0673 0.1486 0.3956
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0012 0.0012
Echinococcus granulosus cathepsin l1 0.1343 0.3036 0.3036
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.007 0.0093 0.0093
Loa Loa (eye worm) transcription factor SMAD2 0.0118 0.0204 0.0204
Mycobacterium ulcerans aldehyde dehydrogenase 0.0128 0.0227 0.148
Schistosoma mansoni cathepsin D (A01 family) 0.0123 0.0215 0.0215
Echinococcus multilocularis cathepsin b 0.4357 1 1
Entamoeba histolytica cysteine protease, putative 0.0351 0.0743 0.2397
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0351 0.0743 0.206
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0373 0.0794 0.2101
Echinococcus granulosus cathepsin L cysteine protease 0.0758 0.1682 0.1682
Trichomonas vaginalis conserved hypothetical protein 0.0204 0.0404 0.112
Trypanosoma cruzi centrin-3 0.0208 0.0413 0.0404
Giardia lamblia Hypothetical protein 0.0072 0.0099 0.0197
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1442 0.3264 0.8713
Schistosoma mansoni importin beta-1 0.0033 0.0008 0.0008
Onchocerca volvulus 0.1343 0.3036 0.6361
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0006 0.0006
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0351 0.0743 0.1997
Trichomonas vaginalis calcium binding protein, putative 0.0204 0.0404 0.112
Giardia lamblia Cathepsin L-like protease 0.0351 0.0743 0.1997
Leishmania major calmodulin, putative 0.0204 0.0404 0.1058
Trypanosoma cruzi kinesin, putative 0.0888 0.1983 0.1976
Loa Loa (eye worm) oxidoreductase 0.0092 0.0145 0.0145
Plasmodium vivax vivapain-2 0.1343 0.3036 1
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0286 0.0593 0.0593
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0515 0.1122 0.2351
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.1453 0.3288 1
Brugia malayi Pre-SET motif family protein 0.0063 0.0079 0.0079
Trypanosoma cruzi aldo/keto reductase, putative 0.0092 0.0145 0.0136
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0351 0.0743 0.2446
Entamoeba histolytica deoxycytidine triphosphate deaminase, putative 0.0053 0.0055 0.0116
Echinococcus multilocularis cathepsin L cysteine protease 0.1343 0.3036 0.3036
Trichomonas vaginalis calmodulin, putative 0.0204 0.0404 0.112
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0032 0.0006 0.0006
Giardia lamblia Aldose reductase 0.0092 0.0145 0.0325
Brugia malayi calpain family protein 1 0.3356 0.7685 0.7685
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0758 0.1682 0.1675
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0025 0.0069
Entamoeba histolytica prolyl oligopeptidase family protein 0.0198 0.0388 0.1222
Trypanosoma cruzi cysteine peptidase, putative 0.1442 0.3264 0.3258
Trichomonas vaginalis centrin, putative 0.0204 0.0404 0.112
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.004 0.0025 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0351 0.0743 0.206
Schistosoma mansoni cercarial elastase (S01 family) 0.0077 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0763 0.1696 0.1696
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0078 0.0078
Entamoeba histolytica hypothetical protein, conserved 0.0198 0.0388 0.1222
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0204 0.0404 0.0396
Schistosoma mansoni hypothetical protein 0.0204 0.0404 0.0404
Brugia malayi cathepsin F-like cysteine proteinase 0.0351 0.0743 0.0743
Echinococcus multilocularis glycoprotein Antigen 5 0.0077 0.0111 0.0111
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0373 0.0794 0.2101
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0204 0.0404 0.1274
Loa Loa (eye worm) hypothetical protein 0.0121 0.0211 0.0211
Trypanosoma cruzi cysteine peptidase, putative 0.1442 0.3264 0.3258
Loa Loa (eye worm) proteasome subunit beta type 2 0.0042 0.0029 0.0029
Echinococcus granulosus dUTP pyrophosphatase 0.0153 0.0285 0.0285
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0099 0.0275
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.159 0.3606 0.3606
Entamoeba histolytica hypothetical protein 0.004 0.0025 0.0017
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0012 0.0034
Loa Loa (eye worm) hypothetical protein 0.0168 0.032 0.032
Echinococcus multilocularis calpain A 0.3564 0.8166 0.8166
Brugia malayi Cathepsin L-like precursor 0.1343 0.3036 0.3036
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.0006 0.0006
Leishmania major kinesin, putative 0.0888 0.1983 0.5284
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0758 0.1682 0.4666
Loa Loa (eye worm) hypothetical protein 0.0373 0.0794 0.0794
Entamoeba histolytica cysteine protease, putative 0.0351 0.0743 0.2397
Entamoeba histolytica cysteine protease, putative 0.1343 0.3036 1
Trypanosoma brucei proteasome beta 6 subunit 0.0067 0.0088 0.0214
Echinococcus granulosus enteropeptidase 0.0077 0.0111 0.0111
Giardia lamblia Cathepsin L precursor 0.0351 0.0743 0.1997
Entamoeba histolytica hypothetical protein 0.0172 0.033 0.1028
Toxoplasma gondii aldehyde dehydrogenase 0.0128 0.0227 0.0607
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.356 0.8157 0.8157
Plasmodium vivax hypothetical protein, conserved 0.0198 0.0388 0.1279
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0012 0.0025
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0373 0.0794 0.2101
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1343 0.3036 0.842
Entamoeba histolytica hypothetical protein 0.004 0.0025 0.0017
Onchocerca volvulus 0.0077 0.0111 0.0233
Echinococcus multilocularis tumor protein p63 0.0356 0.0756 0.0756
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0032 0.0006 0.0006
Onchocerca volvulus 0.0063 0.0079 0.0165
Loa Loa (eye worm) hypothetical protein 0.2095 0.4773 0.4773
Trypanosoma brucei cysteine peptidase C (CPC) 0.159 0.3606 0.9629
Plasmodium vivax vivapain-2 0.1343 0.3036 1
Brugia malayi Deoxynucleoside kinase family protein 0.0072 0.0099 0.0099
Brugia malayi prolyl oligopeptidase family protein 0.0286 0.0593 0.0593
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0067 0.0088 0.0212
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0077 0.0111 0.0111
Onchocerca volvulus 0.0092 0.0145 0.0303
Loa Loa (eye worm) hypothetical protein 0.0168 0.032 0.032
Leishmania major programmed cell death 6 protein-like protein 0.0204 0.0404 0.1058
Plasmodium vivax unspecified product 0.0407 0.0872 0.2871
Loa Loa (eye worm) hypothetical protein 0.0198 0.0388 0.0388
Mycobacterium leprae Conserved hypothetical protein 0.0065 0.0083 0.048
Trypanosoma cruzi metacaspase 5, putative 0.0722 0.1601 0.1593
Loa Loa (eye worm) hypothetical protein 0.0033 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0032 0.0006 0.0006
Echinococcus granulosus calumenin 0.0208 0.0413 0.0413
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0351 0.0743 0.206
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.0006 0.0006
Schistosoma mansoni neuronal calcium sensor 0.0204 0.0404 0.0404
Echinococcus multilocularis Regulator of G protein signaling 20 0.004 0.0025 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1343 0.3036 0.842
Trichomonas vaginalis conserved hypothetical protein 0.0722 0.1601 0.4439
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0351 0.0743 0.2446
Brugia malayi Probable ATP-dependent helicase DHX35 0.0105 0.0174 0.0174
Trypanosoma cruzi hypothetical protein, conserved 0.0198 0.0388 0.038
Loa Loa (eye worm) hypothetical protein 0.0407 0.0872 0.0872
Trypanosoma brucei metacaspase MCA2 0.0722 0.1601 0.4262
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0032 0.0006 0.0006
Giardia lamblia Hypothetical protein 0.0351 0.0743 0.1997
Loa Loa (eye worm) hypothetical protein 0.004 0.0025 0.0025
Schistosoma mansoni regulator of G protein signaling 0.004 0.0025 0.0025
Echinococcus multilocularis calcium uptake protein 1 0.0208 0.0413 0.0413
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0063 0.0079 0.0079
Brugia malayi cathepsin L-like cysteine proteinase 0.0351 0.0743 0.0743
Loa Loa (eye worm) hypothetical protein 0.0077 0.0111 0.0111
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.0006 0.0006
Brugia malayi Proteasome A-type and B-type family protein 0.0087 0.0133 0.0133
Entamoeba histolytica cysteine protease, putative 0.0351 0.0743 0.2397
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0032 0.0006 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0099 0.0275
Mycobacterium tuberculosis Probable peptidase 0.0673 0.1486 0.4499
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0025 0.0025
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0373 0.0794 0.2102
Giardia lamblia Thymidine kinase 0.0257 0.0526 0.1389
Schistosoma mansoni RAR-like nuclear receptor 0.0032 0.0006 0.0006
Echinococcus multilocularis gamma secretase subunit aph 1 0.0246 0.0502 0.0502
Toxoplasma gondii exonuclease III APE 0.0056 0.0061 0.0162
Loa Loa (eye worm) hypothetical protein 0.0198 0.0388 0.0388
Echinococcus granulosus axis inhibition protein axin 0.004 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0035 0.0012 0.0012
Entamoeba histolytica cysteine protease, putative 0.0758 0.1682 0.5512
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0063 0.0079 0.0079
Brugia malayi cathepsin F-like cysteine proteinase 0.0407 0.0872 0.0872
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0722 0.1601 0.4275
Trichomonas vaginalis aldo/keto reductase, putative 0.0092 0.0145 0.0401
Trypanosoma cruzi thymidine kinase, putative 0.0257 0.0526 0.0517
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0373 0.0794 0.0786
Loa Loa (eye worm) beta-lactamase 0.0035 0.0012 0.0012
Onchocerca volvulus 0.05 0.1086 0.2276
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0758 0.1682 0.4666
Trypanosoma cruzi thymidine kinase, putative 0.0257 0.0526 0.0517
Schistosoma mansoni reticulocalbin 0.0204 0.0404 0.0404
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0077 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0204 0.0404 0.0404
Schistosoma mansoni neuronal calcium sensor 0.0204 0.0404 0.0404
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0077 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0351 0.0743 0.0743
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0032 0.0006 0.0006
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.0061 0.02
Echinococcus granulosus centrin 2 0.0204 0.0404 0.0404
Schistosoma mansoni cercarial elastase (S01 family) 0.0077 0.0111 0.0111
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.007 0.0093 0.0093
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase, putative 0.0053 0.0055 0.0116
Trypanosoma brucei centrin-3 0.0208 0.0413 0.1083
Leishmania major centrin, putative 0.0204 0.0404 0.1058
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0673 0.1486 0.1479
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.126 0.2844 0.2838
Trichomonas vaginalis aldo-keto reductase, putative 0.0092 0.0145 0.0401
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0032 0.0006 0.0006
Echinococcus granulosus regulator of G protein signaling 3 0.004 0.0025 0.0025
Leishmania major proteasome beta 2 subunit, putative 0.0042 0.0029 0.0053
Echinococcus granulosus caspase 2 0.1143 0.2574 0.2574
Schistosoma mansoni regulator of G protein signaling 0.004 0.0025 0.0025
Loa Loa (eye worm) animal heme peroxidase 0.0168 0.032 0.032
Brugia malayi RNA, U transporter 1 0.0094 0.0148 0.0148
Trypanosoma cruzi cysteine peptidase, putative 0.0407 0.0872 0.0864
Trichomonas vaginalis calpain, putative 0.0373 0.0794 0.2201
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0373 0.0794 0.2201
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0099 0.0275
Loa Loa (eye worm) deoxynucleoside kinase 0.0072 0.0099 0.0099
Echinococcus multilocularis calbindin 32 0.0208 0.0413 0.0413
Onchocerca volvulus 0.0467 0.1012 0.212
Echinococcus multilocularis apoptotic protease activating factor 1 0.0421 0.0905 0.0905
Echinococcus granulosus thymidine kinase 0.0323 0.0679 0.0679
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0246 0.0502 0.0502
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.004 0.0025 0.0025
Echinococcus granulosus calbindin 32 0.0208 0.0413 0.0413
Trypanosoma brucei prolyl endopeptidase 0.165 0.3745 1
Brugia malayi Cytochrome P450 family protein 0.0055 0.0059 0.0059
Brugia malayi Animal haem peroxidase family protein 0.0168 0.032 0.032
Onchocerca volvulus 0.0032 0.0006 0.0012
Trichomonas vaginalis calmodulin, putative 0.0204 0.0404 0.112
Loa Loa (eye worm) hypothetical protein 0.0077 0.0111 0.0111
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.0006 0.0006
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0204 0.0404 0.106
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0067 0.0088 0.0088
Echinococcus multilocularis calmodulin 0.0204 0.0404 0.0404
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0012 0.0004
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0373 0.0794 0.0786
Brugia malayi hypothetical protein 0.0168 0.032 0.032
Brugia malayi Cathepsin L-like precursor 0.0937 0.2097 0.2097
Trichomonas vaginalis calmodulin, putative 0.0204 0.0404 0.112
Entamoeba histolytica cysteine protease, putative 0.0758 0.1682 0.5512
Entamoeba histolytica hypothetical protein 0.0072 0.0099 0.0264
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1343 0.3036 0.842
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0079 0.0079
Loa Loa (eye worm) oxidoreductase 0.0092 0.0145 0.0145
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0117 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.0205 0.0405 0.0405
Schistosoma mansoni ef hand domain family member A2 0.0204 0.0404 0.0404
Onchocerca volvulus Cathepsin L homolog 0.0351 0.0743 0.1556
Loa Loa (eye worm) hypothetical protein 0.0077 0.0111 0.0111
Echinococcus granulosus peroxidasin 0.0168 0.032 0.032
Entamoeba histolytica cysteine protease, putative 0.0758 0.1682 0.5512
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0087 0.0133 0.0816
Trypanosoma cruzi metacaspase, putative 0.0722 0.1601 0.1593
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0198 0.0388 0.1077
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.159 0.3606 0.36
Trichomonas vaginalis conserved hypothetical protein 0.0722 0.1601 0.4439
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0373 0.0794 0.0786
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0089 0.0137 0.0137
Plasmodium vivax serine-repeat antigen (SERA) 0.0351 0.0743 0.2446
Echinococcus multilocularis thyroid hormone receptor alpha 0.0032 0.0006 0.0006
Brugia malayi cathepsin L precursor 0.0351 0.0743 0.0743
Trypanosoma cruzi oligopeptidase b 0.0673 0.1486 0.1479
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0032 0.0006 0.0012
Echinococcus granulosus EF hand domain containing family member A2 0.0204 0.0404 0.0404
Echinococcus multilocularis ecdysone induced protein 78C 0.0032 0.0006 0.0006
Trypanosoma cruzi cysteine proteinase, putative 0.0758 0.1682 0.1675
Loa Loa (eye worm) proteasome subunit beta type 1 0.0067 0.0088 0.0088
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.007 0.0093 0.0093
Schistosoma mansoni Mername-AA248 (C02 family) 0.126 0.2844 0.2844
Brugia malayi prolyl oligopeptidase family protein 0.0515 0.1122 0.1122
Echinococcus multilocularis centrin 2 0.0204 0.0404 0.0404
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0351 0.0743 0.206
Echinococcus granulosus glycogen phosphorylase 0.0106 0.0177 0.0177
Loa Loa (eye worm) calpain 0.126 0.2844 0.2844
Entamoeba histolytica glycogen phosphorylase, putative 0.0046 0.0038 0.0061
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0373 0.0794 0.2101
Trichomonas vaginalis calmodulin, putative 0.0204 0.0404 0.112
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1343 0.3036 0.3036
Schistosoma mansoni thyroid hormone receptor 0.0032 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0351 0.0743 0.206
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0373 0.0794 0.2101
Entamoeba histolytica thymidine kinase, putative 0.0257 0.0526 0.1677
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0378 0.0806 0.0806
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0351 0.0743 0.0743
Schistosoma mansoni cercarial elastase (S01 family) 0.0077 0.0111 0.0111
Toxoplasma gondii troponin c, isotype gamma, putative 0.0204 0.0404 0.1079
Brugia malayi beta-lactamase family protein 0.0035 0.0012 0.0012
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0286 0.0593 0.0585
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1442 0.3264 0.8713
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0092 0.0145 0.0145
Echinococcus granulosus calpain A 0.3564 0.8166 0.8166
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.007 0.0093 0.0225
Trypanosoma brucei Metacaspase-4 0.0722 0.1601 0.4262
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0128 0.0227 0.0586
Echinococcus granulosus programmed cell death protein 0.0208 0.0413 0.0413
Trichomonas vaginalis calcineurin B subunit, putative 0.0204 0.0404 0.112
Trichomonas vaginalis aldo-keto reductase, putative 0.0092 0.0145 0.0401
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0515 0.1122 0.1122
Loa Loa (eye worm) calpain family protein 1 0.2468 0.5635 0.5635
Brugia malayi Regulator of G protein signaling domain containing protein 0.004 0.0025 0.0025
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0032 0.0006 0.0006
Brugia malayi calpain 5 0.0888 0.1983 0.1983
Echinococcus granulosus apoptotic protease activating factor 1 0.0421 0.0905 0.0905
Onchocerca volvulus Huntingtin homolog 0.0121 0.0211 0.0442
Onchocerca volvulus 0.0077 0.0111 0.0233
Echinococcus granulosus ecdysone induced protein 78C 0.0032 0.0006 0.0006
Leishmania major protein kinase, putative 0.0204 0.0404 0.1058
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0351 0.0743 0.0743
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0065 0.0082 0.0082
Schistosoma mansoni glycogen phosphorylase 0.0106 0.0177 0.0177
Onchocerca volvulus 0.1343 0.3036 0.6361
Echinococcus granulosus cysteine protease 0.0758 0.1682 0.1682
Loa Loa (eye worm) hypothetical protein 0.0351 0.0743 0.0743
Schistosoma mansoni calpain-7 (C02 family) 0.126 0.2844 0.2844
Trypanosoma cruzi I/6 autoantigen, putative 0.0204 0.0404 0.0396
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.004 0.0025 0.0025
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0373 0.0794 0.2201
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0077 0.0111 0.0111
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0222 0.0445 0.1322
Giardia lamblia Cathepsin B precursor 0.0351 0.0743 0.1997
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4357 1 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0722 0.1601 0.4439
Onchocerca volvulus 0.0168 0.032 0.067
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0063 0.0079 0.021
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.0006 0.0006
Echinococcus granulosus aldo keto reductase 0.0092 0.0145 0.0145
Entamoeba histolytica hypothetical protein 0.0153 0.0285 0.088
Onchocerca volvulus 0.0077 0.0111 0.0233
Schistosoma mansoni cathepsin B (C01 family) 0.0351 0.0743 0.0743
Loa Loa (eye worm) hypothetical protein 0.0421 0.0905 0.0905
Loa Loa (eye worm) steroid hormone receptor 0.0032 0.0006 0.0006
Onchocerca volvulus 0.0092 0.0145 0.0303
Onchocerca volvulus 0.0168 0.032 0.067
Leishmania major centrin, putative 0.0204 0.0404 0.1058
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0032 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1343 0.3036 0.842
Trypanosoma brucei thymidine kinase 0.0257 0.0526 0.1385
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.3356 0.7685 0.7685
Brugia malayi programmed cell death protein 6 0.0204 0.0404 0.0404
Entamoeba histolytica cysteine proteinase, putative 0.1343 0.3036 1
Trichomonas vaginalis calcium binding protein, putative 0.0204 0.0404 0.112
Entamoeba histolytica grainin, putative 0.0208 0.0413 0.1302
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.165 0.3745 0.3745
Schistosoma mansoni caspase-7 (C14 family) 0.1143 0.2574 0.2574
Brugia malayi ecdysteroid receptor 0.0032 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0168 0.032 0.032
Loa Loa (eye worm) hypothetical protein 0.0351 0.0743 0.0743
Entamoeba histolytica protein kinase, putative 0.0888 0.1983 0.6507
Echinococcus multilocularis aldo keto reductase 0.0092 0.0145 0.0145
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0077 0.0111 0.0111
Giardia lamblia Cathepsin L precursor 0.0351 0.0743 0.1997
Schistosoma mansoni axis inhibition protein axin 0.004 0.0025 0.0025
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0351 0.0743 0.2446
Echinococcus multilocularis peroxidasin 0.0168 0.032 0.032
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1343 0.3036 0.842
Echinococcus multilocularis Mastin 0.0077 0.0111 0.0111
Plasmodium falciparum serine repeat antigen 6 0.0351 0.0743 0.2446
Giardia lamblia Cathepsin B precursor 0.0351 0.0743 0.1997
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0092 0.0145 0.0145
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.0225 0.0452 0.1434
Onchocerca volvulus 0.0077 0.0111 0.0233
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0373 0.0794 0.2102
Trypanosoma cruzi calmodulin, putative 0.0204 0.0404 0.0396
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0087 0.0133 0.0124
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0137 0.0137
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0204 0.0404 0.0396
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0793 0.1764 0.1764
Loa Loa (eye worm) hypothetical protein 0.0032 0.0006 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0025 0.0069
Plasmodium falciparum metacaspase-like protein 0.0722 0.1601 0.5272
Onchocerca volvulus 0.0035 0.0012 0.0026
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0286 0.0593 0.1584
Echinococcus multilocularis regulator of G protein signaling 3 0.004 0.0025 0.0025
Echinococcus multilocularis regulator of G protein signaling 7 0.004 0.0025 0.0025
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0092 0.0145 0.0364
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0067 0.0088 0.0226
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0204 0.0404 0.112
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0092 0.0145 0.0145
Brugia malayi hypothetical protein 0.025 0.051 0.051
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0351 0.0743 0.206
Trypanosoma cruzi hypothetical protein, conserved 0.0198 0.0388 0.038
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0092 0.0145 0.0898
Loa Loa (eye worm) hypothetical protein 0.0722 0.1601 0.1601
Entamoeba histolytica hypothetical protein 0.0053 0.0055 0.0116
Loa Loa (eye worm) hypothetical protein 0.0467 0.1012 0.1012
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0208 0.0413 0.0413
Schistosoma mansoni survival motor neuron protein 0.0051 0.005 0.005
Echinococcus granulosus calpain 7 C02 family 0.126 0.2844 0.2844
Entamoeba histolytica calcium binding family protein 0.0204 0.0404 0.1274
Brugia malayi calpain 7 0.126 0.2844 0.2844
Loa Loa (eye worm) hypothetical protein 0.0467 0.1012 0.1012
Brugia malayi Cell death protein 3 precursor 0.1143 0.2574 0.2574
Toxoplasma gondii calmodulin CAM1 0.0208 0.0413 0.1102
Onchocerca volvulus 0.0158 0.0298 0.0624
Trichomonas vaginalis conserved hypothetical protein 0.0722 0.1601 0.4439
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1343 0.3036 0.842
Onchocerca volvulus 0.0208 0.0413 0.0864
Onchocerca volvulus 0.1343 0.3036 0.6361
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0373 0.0794 0.2101
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1442 0.3264 0.8713
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0042 0.0029 0.0094
Brugia malayi regulator of G-protein signaling rgs-7 0.004 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.1343 0.3036 0.3036
Loa Loa (eye worm) hypothetical protein 0.0168 0.032 0.032
Trypanosoma cruzi cysteine peptidase, putative 0.0758 0.1682 0.1675
Echinococcus granulosus cathepsin b 0.4357 1 1
Onchocerca volvulus Cathepsin L homolog 0.1343 0.3036 0.6361
Loa Loa (eye worm) hypothetical protein 0.0204 0.0404 0.0404
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0012 0.0034
Brugia malayi hypothetical protein 0.0467 0.1012 0.1012
Echinococcus granulosus cathepsin b 0.4357 1 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0373 0.0794 0.2101
Toxoplasma gondii calcium-dependent protein kinase 0.0208 0.0413 0.1102
Plasmodium falciparum centrin-1 0.0204 0.0404 0.1331
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0515 0.1122 0.1122
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0758 0.1682 0.1682
Entamoeba histolytica cysteine protease, putative 0.0758 0.1682 0.5512
Trypanosoma brucei cysteine peptidase, putative 0.0373 0.0794 0.2102
Loa Loa (eye worm) hypothetical protein 0.0168 0.032 0.032
Loa Loa (eye worm) hypothetical protein 0.0032 0.0006 0.0006
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0089 0.0137 0.0137
Plasmodium vivax hypothetical protein, conserved 0.0208 0.0413 0.1359
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0087 0.0133 0.0367
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0373 0.0794 0.0786
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0204 0.0404 0.0404
Entamoeba histolytica cysteine protease, putative 0.0758 0.1682 0.5512
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0046 0.0038 0.0199
Trichomonas vaginalis aldo/keto reductase, putative 0.0092 0.0145 0.0401
Plasmodium falciparum plasmepsin X 0.0109 0.0185 0.0608
Schistosoma mansoni calmodulin 0.0204 0.0404 0.0404
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0373 0.0794 0.2101
Brugia malayi Papain family cysteine protease containing protein 0.0351 0.0743 0.0743
Giardia lamblia Cathepsin B precursor 0.159 0.3606 1
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0067 0.0088 0.0079
Trichomonas vaginalis aldo-keto reductase, putative 0.0092 0.0145 0.0401
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1343 0.3036 0.842
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0128 0.0227 0.0656
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1343 0.3036 0.842
Trypanosoma cruzi metacaspase, putative 0.0722 0.1601 0.1593
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0092 0.0145 0.0145
Loa Loa (eye worm) hypothetical protein 0.0063 0.0079 0.0079
Trypanosoma brucei calpain, putative 0.0373 0.0794 0.2102
Trypanosoma brucei kinesin, putative 0.0888 0.1983 0.5284
Echinococcus granulosus calpain A 0.126 0.2844 0.2844
Brugia malayi prolyl oligopeptidase family protein 0.0198 0.0388 0.0388
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0056 0.0061 0.0353
Chlamydia trachomatis deoxyuridine 5'-triphosphate nucleotidohydrolase 0.0153 0.0285 1
Loa Loa (eye worm) hypothetical protein 0.3356 0.7685 0.7685
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0092 0.0145 0.0145
Plasmodium vivax metacaspase 1, putative 0.0722 0.1601 0.5272
Giardia lamblia Deoxynucleoside kinase 0.0072 0.0099 0.0197
Trypanosoma brucei metacaspase 0.0722 0.1601 0.4262
Schistosoma mansoni hypothetical protein 0.0409 0.0877 0.0877
Giardia lamblia Aldose reductase 0.0092 0.0145 0.0325
Echinococcus multilocularis thymidine kinase 0.0323 0.0679 0.0679
Onchocerca volvulus 0.0077 0.0111 0.0233
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0077 0.0111 0.0111
Echinococcus granulosus acylamino acid releasing enzyme 0.0198 0.0388 0.0388
Schistosoma mansoni calmodulin related calcium binding protein 0.0204 0.0404 0.0404
Toxoplasma gondii EF hand domain-containing protein 0.0204 0.0404 0.1079
Echinococcus granulosus cpg binding protein 0.003 0.0002 0.0002
Schistosoma mansoni ap endonuclease 0.0056 0.0061 0.0061
Entamoeba histolytica cysteine protease, putative 0.0758 0.1682 0.5512
Echinococcus granulosus snurportin 1 0.0351 0.0744 0.0744
Mycobacterium ulcerans deoxycytidine triphosphate deaminase 0.0053 0.0055 0.0311
Echinococcus granulosus regulator of G protein signaling 7 0.004 0.0025 0.0025
Leishmania major proteasome beta 5 subunit, putative 0.0087 0.0133 0.0332
Echinococcus multilocularis cathepsin L cysteine protease 0.1343 0.3036 0.3036
Entamoeba histolytica cysteine proteinase, putative 0.0758 0.1682 0.5512
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0673 0.1486 0.1479
Loa Loa (eye worm) dUTP diphosphatase 0.0153 0.0285 0.0285
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0065 0.0082 0.0213
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0032 0.0006 0.0006
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0067 0.0088 0.0088
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0673 0.1486 1
Trichomonas vaginalis conserved hypothetical protein 0.0198 0.0388 0.1077
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.356 0.8157 0.8157
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1343 0.3036 0.842
Trypanosoma cruzi kinesin, putative 0.0888 0.1983 0.1976
Trichomonas vaginalis aldo-keto reductase, putative 0.0092 0.0145 0.0401
Schistosoma mansoni hypothetical protein 0.0038 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.2468 0.5635 0.5635
Plasmodium falciparum serine repeat antigen 3 0.0351 0.0743 0.2446
Echinococcus granulosus tumor protein p63 0.0356 0.0756 0.0756
Echinococcus multilocularis acylamino acid releasing enzyme 0.0198 0.0388 0.0388
Entamoeba histolytica cysteine protease, putative 0.0758 0.1682 0.5512
Brugia malayi Animal haem peroxidase family protein 0.0168 0.032 0.032
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.126 0.2844 0.759
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0351 0.0743 0.206
Echinococcus granulosus FTZ F1 alpha 0.0032 0.0006 0.0006
Trypanosoma brucei metacaspase 5, putative 0.0722 0.1601 0.4262
Brugia malayi prolyl oligopeptidase family protein 0.165 0.3745 0.3745
Onchocerca volvulus 0.0351 0.0743 0.1556
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0351 0.0743 0.2446
Brugia malayi Cytochrome P450 family protein 0.0033 0.0009 0.0009
Brugia malayi beta-lactamase 0.0035 0.0012 0.0012
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.004 0.0025 0.0025
Brugia malayi cathepsin Z-like cysteine proteinase 0.0351 0.0743 0.0743
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0351 0.0743 0.2397
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0063 0.0168
Echinococcus multilocularis dUTP pyrophosphatase 0.0153 0.0285 0.0285
Entamoeba histolytica hypothetical protein 0.0172 0.033 0.1028
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.126 0.2844 0.759
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.004 0.0025 0.0025
Wolbachia endosymbiont of Brugia malayi dUTPase 0.0153 0.0285 1
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0092 0.0145 0.0145
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0092 0.0145 0.0145
Loa Loa (eye worm) hypothetical protein 0.0032 0.0006 0.0006
Mycobacterium ulcerans proteasome PrcB 0.0087 0.0133 0.0839
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0351 0.0743 0.2446
Echinococcus granulosus neuronal calcium sensor 0.0204 0.0404 0.0404
Onchocerca volvulus 0.2095 0.4773 1
Trypanosoma brucei prostaglandin f synthase 0.0092 0.0145 0.0366
Schistosoma mansoni cpg binding protein 0.003 0.0002 0.0002
Echinococcus granulosus proteasome prosome macropain 0.0087 0.0133 0.0133
Brugia malayi beta-lactamase family protein 0.0035 0.0012 0.0012
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0373 0.0794 0.0786
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0758 0.1682 0.1682
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0032 0.0006 0.0006
Loa Loa (eye worm) trypsin family protein 0.0077 0.0111 0.0111
Brugia malayi Cathepsin L-like precursor 0.1343 0.3036 0.3036
Echinococcus granulosus caspase 0.1833 0.4167 0.4167
Loa Loa (eye worm) hypothetical protein 0.0168 0.032 0.032
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0117 0.0202 0.0202
Leishmania major cathepsin L-like protease 0.1442 0.3264 0.8713
Trichomonas vaginalis calcium binding protein, putative 0.0204 0.0404 0.112
Brugia malayi photoreceptor-specific nuclear receptor 0.0032 0.0006 0.0006
Brugia malayi Animal haem peroxidase family protein 0.0168 0.032 0.032
Schistosoma mansoni regulator of G protein signaling 0.004 0.0025 0.0025
Brugia malayi fibroinase precursor 0.0351 0.0743 0.0743
Brugia malayi hypothetical protein 0.0158 0.0298 0.0298
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0373 0.0794 0.0786
Trichomonas vaginalis calcineurin B subunit, putative 0.0208 0.0413 0.1144
Echinococcus multilocularis cpg binding protein 0.003 0.0002 0.0002
Brugia malayi EF hand family protein 0.0208 0.0413 0.0413
Trichomonas vaginalis myosin light chain 1, putative 0.0204 0.0404 0.112
Onchocerca volvulus Bile acid receptor homolog 0.0032 0.0006 0.0012
Brugia malayi dUTP diphosphatase 0.0153 0.0285 0.0285
Echinococcus multilocularis calumenin 0.0208 0.0413 0.0413
Loa Loa (eye worm) hypothetical protein 0.0032 0.0006 0.0006
Giardia lamblia Cathepsin B precursor 0.159 0.3606 1
Entamoeba histolytica cysteine proteinase, putative 0.0758 0.1682 0.5512
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0009 0.0009
Echinococcus granulosus calcium uptake protein 1 0.0208 0.0413 0.0413
Schistosoma mansoni hypothetical protein 0.0351 0.0744 0.0744
Brugia malayi exodeoxyribonuclease III family protein 0.0056 0.0061 0.0061
Trichomonas vaginalis aldo-keto reductase, putative 0.0092 0.0145 0.0401
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0351 0.0743 0.2446
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0351 0.0743 0.1997
Brugia malayi Pre-SET motif family protein 0.0439 0.0946 0.0946
Trichomonas vaginalis aldo-keto reductase, putative 0.0092 0.0145 0.0401
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0373 0.0794 0.0786
Echinococcus granulosus cathepsin L cysteine proteinase 0.1343 0.3036 0.3036
Entamoeba histolytica cysteine protease, putative 0.0758 0.1682 0.5512
Giardia lamblia Cysteine protease 0.0351 0.0743 0.1997
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0092 0.0145 0.0145
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0351 0.0743 0.2446
Brugia malayi Steroid receptor seven-up type 2 0.0032 0.0006 0.0006
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0077 0.0111 0.0111
Echinococcus multilocularis caspase 3 0.1111 0.2498 0.2498
Echinococcus granulosus Regulator of G protein signaling 20 0.004 0.0025 0.0025
Echinococcus granulosus aldo keto reductase 0.0092 0.0145 0.0145
Entamoeba histolytica cysteine protease, putative 0.0351 0.0743 0.2397
Toxoplasma gondii deoxyuridine 5'-triphosphate nucleotidohydrolase, putative 0.0153 0.0285 0.0761
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0087 0.0133 0.0133
Brugia malayi calpain 5 0.0373 0.0794 0.0794
Leishmania major cathepsin L-like protease 0.1442 0.3264 0.8713
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0373 0.0794 0.2119
Brugia malayi Cathepsin L-like precursor 0.0937 0.2097 0.2097
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0373 0.0794 0.2101
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1343 0.3036 0.842
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0515 0.1122 0.1122
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1343 0.3036 0.3036
Echinococcus multilocularis prolyl endopeptidase 0.165 0.3745 0.3745
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0032 0.0006 0.0006
Brugia malayi Amyloid A4 extracellular domain containing protein 0.0969 0.217 0.217
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0092 0.0145 0.0145
Leishmania major hypothetical protein, unknown function 0.0373 0.0794 0.2101
Loa Loa (eye worm) hypothetical protein 0.0077 0.0111 0.0111
Echinococcus granulosus calpain 0.126 0.2844 0.2844
Schistosoma mansoni cercarial elastase (S01 family) 0.0077 0.0111 0.0111
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0032 0.0006 0.0006
Onchocerca volvulus 0.0035 0.0012 0.0026
Echinococcus multilocularis NADH ubiquinone oxidoreductase 42 kDa subunit 0.0072 0.0099 0.0099
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.356 0.8157 0.8157
Plasmodium falciparum peptidase, putative 0.0198 0.0388 0.1279
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1343 0.3036 1
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0042 0.0029 0.0076
Echinococcus multilocularis calmodulin 0.0204 0.0404 0.0404
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1343 0.3036 0.842
Brugia malayi Animal haem peroxidase family protein 0.0168 0.032 0.032
Brugia malayi Trypsin family protein 0.0077 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.004 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0092 0.0145 0.0145
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0032 0.0006 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0099 0.0275
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0092 0.0145 0.0145
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0092 0.0145 0.0145
Schistosoma mansoni peroxidasin 0.0168 0.032 0.032
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0032 0.0006 0.0006
Echinococcus multilocularis survival motor neuron protein 1 0.025 0.051 0.051
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0373 0.0794 0.2101
Trichomonas vaginalis calcium binding proteins, putative 0.0204 0.0404 0.112
Trypanosoma cruzi I/6 autoantigen, putative 0.0204 0.0404 0.0396
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.0061 0.02
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0099 0.0275
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.004 0.0025 0.0025
Leishmania major cathepsin L-like protease 0.1343 0.3036 0.8104
Mycobacterium ulcerans aldehyde dehydrogenase 0.0128 0.0227 0.148
Plasmodium falciparum importin beta, putative 0.0033 0.0008 0.0027
Trichomonas vaginalis calmodulin, putative 0.0204 0.0404 0.112
Loa Loa (eye worm) hypothetical protein 0.0351 0.0743 0.0743
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0373 0.0794 0.0786
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0937 0.2097 0.5814
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0092 0.0145 0.0145
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0373 0.0794 0.0786
Trypanosoma brucei Calpain-like protein CALP1.3 0.0373 0.0794 0.2102
Entamoeba histolytica calmodulin, putative 0.0204 0.0404 0.1274
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0373 0.0794 0.0786
Trypanosoma cruzi conserved protein 0.0373 0.0794 0.0786
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0722 0.1601 0.4439
Trypanosoma cruzi caltractin, putative 0.0204 0.0404 0.0396
Echinococcus multilocularis FTZ F1 alpha 0.0032 0.0006 0.0006
Entamoeba histolytica hypothetical protein 0.0072 0.0099 0.0264
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0128 0.0227 0.0227
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0077 0.0111 0.0111
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0351 0.0743 0.1997
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.004 0.0025 0.0025
Onchocerca volvulus 0.1343 0.3036 0.6361
Loa Loa (eye worm) CYP4Cod1 0.0033 0.0009 0.0009
Toxoplasma gondii hypothetical protein 0.0373 0.0794 0.2119
Leishmania major hypothetical protein, conserved 0.0035 0.0012 0.001
Onchocerca volvulus 0.0077 0.0111 0.0233
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0351 0.0743 0.0743
Leishmania major calpain family cysteine protease-like protein 0.0373 0.0794 0.2101
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0032 0.0006 0.0006
Schistosoma mansoni aldehyde dehydrogenase 0.0128 0.0227 0.0227
Plasmodium falciparum deoxyuridine 5'-triphosphate nucleotidohydrolase 0.0153 0.0285 0.0939
Loa Loa (eye worm) hypothetical protein 0.0168 0.032 0.032
Toxoplasma gondii aspartyl protease ASP3 0.0109 0.0185 0.0493
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0204 0.0404 0.0396
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0032 0.0006 0.0006
Schistosoma mansoni retinoic acid receptor RXR 0.0032 0.0006 0.0006
Echinococcus granulosus calpain 5 0.126 0.2844 0.2844
Schistosoma mansoni cercarial elastase (S01 family) 0.0077 0.0111 0.0111
Loa Loa (eye worm) animal heme peroxidase 0.0168 0.032 0.032
Plasmodium vivax aspartyl protease, putative 0.0109 0.0185 0.0608
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0056 0.0061 0.0148
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0012 0.0012
Leishmania major cathepsin L-like protease 0.1343 0.3036 0.8104
Trypanosoma cruzi cysteine peptidase, putative 0.1442 0.3264 0.3258
Trichomonas vaginalis thymidine kinase, putative 0.0257 0.0526 0.1458
Loa Loa (eye worm) hypothetical protein 0.0121 0.0211 0.0211
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0032 0.0006 0.0006
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0373 0.0794 0.2101
Leishmania major cathepsin L-like protease 0.1343 0.3036 0.8104
Schistosoma mansoni microtubule-associated protein tau 0.1446 0.3272 0.3272
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0012 0.0034
Leishmania major oligopeptidase b 0.0673 0.1486 0.3955
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0012 0.0012
Entamoeba histolytica cysteine proteinase, putative 0.0937 0.2097 0.6885
Loa Loa (eye worm) runx1 0.0059 0.0067 0.0067
Schistosoma mansoni calpain-2 (C02 family) 0.0373 0.0794 0.0794
Onchocerca volvulus Glycogen phosphorylase homolog 0.0106 0.0177 0.0372
Echinococcus granulosus regulator of G protein signaling 3 0.004 0.0025 0.0025
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0092 0.0145 0.0145
Brugia malayi Trypsin family protein 0.0077 0.0111 0.0111
Trypanosoma cruzi centrin, putative 0.0208 0.0413 0.0404
Loa Loa (eye worm) hypothetical protein 0.0937 0.2097 0.2097
Trypanosoma cruzi metacaspase, putative 0.0722 0.1601 0.1593
Echinococcus granulosus transmembrane protease serine 3 0.0077 0.0111 0.0111
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0093 0.0084
Schistosoma mansoni cercarial elastase (S01 family) 0.0077 0.0111 0.0111
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0089 0.0137 0.0137
Trichomonas vaginalis calmodulin-2, putative 0.0204 0.0404 0.112
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0092 0.0145 0.0401
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0032 0.0006 0.0006
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.0225 0.0452 0.1434
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.159 0.3606 1
Loa Loa (eye worm) hypothetical protein 0.0077 0.0111 0.0111
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0092 0.0145 0.0145
Brugia malayi Cathepsin L-like cysteine proteinase 0.0937 0.2097 0.2097
Brugia malayi Cathepsin L-like precursor 0.1343 0.3036 0.3036
Toxoplasma gondii cathepsin CPC1 0.0351 0.0743 0.1984
Toxoplasma gondii proteasome subunit beta type, putative 0.0087 0.0133 0.0354
Loa Loa (eye worm) hypothetical protein 0.0077 0.0111 0.0111
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.1833 0.4167 0.4167
Brugia malayi MH2 domain containing protein 0.0118 0.0204 0.0204
Trypanosoma brucei calpain-like protein, putative 0.126 0.2844 0.759
Loa Loa (eye worm) oxidoreductase 0.0092 0.0145 0.0145
Echinococcus multilocularis caspase 8 0.0722 0.1601 0.1601
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0092 0.0145 0.0401
Plasmodium falciparum proteasome subunit beta type-5 0.0087 0.0133 0.0437
Plasmodium falciparum serine repeat antigen 8 0.0351 0.0743 0.2446
Echinococcus granulosus Mastin 0.0077 0.0111 0.0111
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0032 0.0006 0.0006
Leishmania major calmodulin-like protein 0.0204 0.0404 0.1058
Brugia malayi Regulator of G protein signaling domain containing protein 0.004 0.0025 0.0025
Entamoeba histolytica cysteine protease, putative 0.0758 0.1682 0.5512
Echinococcus granulosus cathepsin l cysteine peptidase 0.1343 0.3036 0.3036
Brugia malayi Papain family cysteine protease containing protein 0.0758 0.1682 0.1682
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0012 0.0012
Onchocerca volvulus Peroxidasin homolog 0.0168 0.032 0.067
Echinococcus multilocularis aldo keto reductase 0.0092 0.0145 0.0145
Plasmodium vivax proteasome subunit beta type-1, putative 0.0067 0.0088 0.0289
Loa Loa (eye worm) calpain 5 0.0888 0.1983 0.1983
Toxoplasma gondii hypothetical protein 0.0198 0.0388 0.1037
Trypanosoma brucei hypothetical protein 0.0373 0.0794 0.2102
Loa Loa (eye worm) hypothetical protein 0.0078 0.0112 0.0112
Trichomonas vaginalis aldo-keto reductase, putative 0.0092 0.0145 0.0401
Schistosoma mansoni cercarial elastase (S01 family) 0.0077 0.0111 0.0111
Leishmania major aldo-keto reductase-like protein 0.0092 0.0145 0.0364
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0056 0.0061 0.0061
Brugia malayi cathepsin L-like precursor 0.0937 0.2097 0.2097
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0373 0.0794 0.0786
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0056 0.0061 0.009
Echinococcus multilocularis aldehyde reductase 0.0065 0.0083 0.0083
Trichomonas vaginalis calmodulin, putative 0.0204 0.0404 0.112
Trypanosoma brucei antigen, putative 0.126 0.2844 0.759
Plasmodium vivax hypothetical protein, conserved 0.0722 0.1601 0.5272
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0032 0.0006 0.0006
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0056 0.0061 0.0052
Echinococcus multilocularis axis inhibition protein axin 0.004 0.0025 0.0025
Brugia malayi hypothetical protein 0.0421 0.0905 0.0905
Loa Loa (eye worm) hypothetical protein 0.0089 0.0137 0.0137
Plasmodium vivax unspecified product 0.0351 0.0743 0.2446
Trichomonas vaginalis aldo-keto reductase, putative 0.0092 0.0145 0.0401
Giardia lamblia Proteasome subunit beta type 1 0.0067 0.0088 0.0166
Loa Loa (eye worm) ctsf protein 0.1343 0.3036 0.3036
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0722 0.1601 0.1601
Brugia malayi hypothetical protein 0.004 0.0025 0.0025
Brugia malayi Melibiase family protein 0.0078 0.0112 0.0112
Mycobacterium ulcerans hypothetical protein 0.0077 0.0111 0.0693
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.0006 0.0006
Echinococcus multilocularis snurportin 1 0.0351 0.0744 0.0744
Echinococcus multilocularis microtubule associated protein 2 0.1446 0.3272 0.3272
Echinococcus multilocularis beta adrenergic receptor kinase 0.004 0.0025 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0351 0.0743 0.206
Trypanosoma cruzi cysteine protease, putative 0.0758 0.1682 0.1675
Entamoeba histolytica cysteine proteinase, putative 0.0758 0.1682 0.5512
Loa Loa (eye worm) hypothetical protein 0.0035 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.2983 0.6824 0.6824
Giardia lamblia Cathepsin B precursor 0.0351 0.0743 0.1997
Trichomonas vaginalis aldo-keto reductase, putative 0.0092 0.0145 0.0401
Entamoeba histolytica prolyl oligopeptidase family protein 0.0198 0.0388 0.1222
Trichomonas vaginalis calcium binding protein, putative 0.0208 0.0413 0.1144
Schistosoma mansoni calpain-7 (C02 family) 0.126 0.2844 0.2844
Trypanosoma brucei calmodulin, putative 0.0208 0.0413 0.1083
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0092 0.0145 0.0145
Entamoeba histolytica hypothetical protein 0.0072 0.0099 0.0264
Schistosoma mansoni thymidine kinase 0.0323 0.0679 0.0679
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0286 0.0593 0.1566
Loa Loa (eye worm) hypothetical protein 0.041 0.088 0.088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0137 0.0137
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0092 0.0145 0.0145
Plasmodium vivax proteasome subunit beta type-5, putative 0.0087 0.0133 0.0437
Entamoeba histolytica cysteine proteinase, putative 0.1343 0.3036 1
Brugia malayi Trypsin family protein 0.0077 0.0111 0.0111
Plasmodium falciparum serine repeat antigen 9 0.0351 0.0743 0.2446
Plasmodium falciparum serine repeat antigen 2 0.0351 0.0743 0.2446
Leishmania major centrin, putative,caltractin, putative 0.0204 0.0404 0.1058
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0722 0.1601 0.4439
Entamoeba histolytica glycogenphosphorylase, putative 0.0046 0.0038 0.0061
Brugia malayi nuclear receptor NHR-88 0.0032 0.0006 0.0006
Trichomonas vaginalis aldo/keto reductase, putative 0.0092 0.0145 0.0401
Loa Loa (eye worm) hypothetical protein 0.0937 0.2097 0.2097
Echinococcus multilocularis calpain 7 (C02 family) 0.126 0.2844 0.2844
Trichomonas vaginalis hypothetical protein 0.0373 0.0794 0.2201
Leishmania major cathepsin L-like protease 0.1343 0.3036 0.8104
Brugia malayi A-kinase anchor protein 10, precursor 0.004 0.0025 0.0025
Loa Loa (eye worm) prolyl oligopeptidase 0.0198 0.0388 0.0388
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.126 0.2844 0.2838
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0089 0.0137 0.0137
Brugia malayi nuclear hormone receptor 0.0032 0.0006 0.0006
Trypanosoma brucei I/6 autoantigen 0.0204 0.0404 0.106
Echinococcus multilocularis cathepsin L 0.0351 0.0743 0.0743
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1442 0.3264 0.8713
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0065 0.0082 0.0082
Loa Loa (eye worm) prolyl oligopeptidase 0.0515 0.1122 0.1122
Echinococcus multilocularis programmed cell death protein 0.0208 0.0413 0.0413
Echinococcus granulosus axis inhibition protein axin 0.004 0.0025 0.0025
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0722 0.1601 0.4439
Plasmodium vivax unspecified product 0.0758 0.1682 0.5541
Toxoplasma gondii EFHC1, putative 0.0204 0.0404 0.1079
Loa Loa (eye worm) fibroinase 0.1343 0.3036 0.3036
Brugia malayi steroid hormone receptor 0.0032 0.0006 0.0006
Giardia lamblia Cathepsin L precursor 0.0351 0.0743 0.1997
Trypanosoma cruzi centrin, putative 0.0208 0.0413 0.0404
Loa Loa (eye worm) hypothetical protein 0.0052 0.0053 0.0053
Schistosoma mansoni nuclear hormone receptor 0.0032 0.0006 0.0006
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0198 0.0388 0.1018
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0056 0.0061 0.0061
Giardia lamblia Encystation-specific protease 0.0351 0.0743 0.1997
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0093 0.0227
Onchocerca volvulus 0.0204 0.0404 0.0846
Echinococcus granulosus beta-adrenergic receptor kinase 0.004 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0077 0.0111 0.0111
Trypanosoma brucei calmodulin, putative 0.0204 0.0404 0.106
Leishmania major cysteine peptidase A (CPA) 0.1343 0.3036 0.8104
Trypanosoma brucei cytochrome P450, putative 0.0033 0.0009 0.0002
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.165 0.3745 1
Mycobacterium tuberculosis Probable oxidoreductase 0.0092 0.0145 0.0404
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0722 0.1601 0.1601
Loa Loa (eye worm) calpain D 0.0373 0.0794 0.0794
Echinococcus multilocularis cathepsin b 0.4357 1 1
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0042 0.0029 0.003
Giardia lamblia Cathepsin L precursor 0.0351 0.0743 0.1997
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0373 0.0794 0.0786
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0006 0.0006
Echinococcus multilocularis transmembrane protease serine 3 0.0077 0.0111 0.0111
Leishmania major cathepsin L-like protease 0.1343 0.3036 0.8104
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0012 0.0041
Toxoplasma gondii cathepsin CPL 0.1343 0.3036 0.8108
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1442 0.3264 0.8713
Plasmodium vivax calpain, putative 0.126 0.2844 0.9368
Toxoplasma gondii cathepsin B 0.159 0.3606 0.9629
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0937 0.2097 0.2097
Toxoplasma gondii aldose reductase, putative 0.0092 0.0145 0.0387
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0117 0.0202 0.0202
Schistosoma mansoni glycogen phosphorylase 0.0046 0.0038 0.0038
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.004 0.0025 0.0025
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.126 0.2844 0.759
Giardia lamblia Cathepsin B precursor 0.0351 0.0743 0.1997
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1442 0.3264 0.8713
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0012 0.0012
Echinococcus multilocularis glycogen phosphorylase 0.0106 0.0177 0.0177
Brugia malayi Importin beta-1 subunit 0.0033 0.0008 0.0008
Onchocerca volvulus 0.0937 0.2097 0.4393
Echinococcus multilocularis regulator of G protein signaling 7 0.004 0.0025 0.0025
Mycobacterium ulcerans lipase LipD 0.0035 0.0012 0.0025
Loa Loa (eye worm) hypothetical protein 0.0158 0.0298 0.0298
Treponema pallidum deoxyuridine 5'-triphosphate nucleotidohydrolase (dut) 0.0153 0.0285 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4357 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0373 0.0794 0.2201
Trichomonas vaginalis conserved hypothetical protein 0.0204 0.0404 0.112
Entamoeba histolytica hypothetical protein 0.0153 0.0285 0.088
Loa Loa (eye worm) hypothetical protein 0.0168 0.032 0.032
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0198 0.0388 0.1222
Schistosoma mansoni cellular tumor antigen P53 0.0052 0.0053 0.0053
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0042 0.0029 0.0029
Schistosoma mansoni thyroid hormone receptor 0.0032 0.0006 0.0006
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0078 0.0112 0.0112
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0722 0.1601 0.4439
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0056 0.0061 0.0061
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0373 0.0794 0.2101
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1343 0.3036 0.842
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0087 0.0133 0.0374
Loa Loa (eye worm) hypothetical protein 0.0168 0.032 0.032
Loa Loa (eye worm) hypothetical protein 0.0168 0.032 0.032
Entamoeba histolytica glycogen phosphorylase, putative 0.0106 0.0177 0.0523
Trichomonas vaginalis calmodulin, putative 0.0208 0.0413 0.1144
Echinococcus multilocularis proteasome (prosome, macropain) 0.0087 0.0133 0.0133
Plasmodium falciparum serine repeat antigen 1 0.0351 0.0743 0.2446
Leishmania major calmodulin-like protein 0.0204 0.0404 0.1058
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0077 0.0111 0.0111
Echinococcus granulosus EF hand domain containing family member A2 0.0208 0.0413 0.0413
Trypanosoma cruzi cysteine proteinase, putative 0.0758 0.1682 0.1675
Echinococcus granulosus glycoprotein Antigen 5 0.0077 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.1143 0.2574 0.2574
Onchocerca volvulus 0.1343 0.3036 0.6361
Schistosoma mansoni cathepsin S (C01 family) 0.0351 0.0743 0.0743
Trypanosoma cruzi calmodulin, putative 0.0204 0.0404 0.0396
Loa Loa (eye worm) hypothetical protein 0.0035 0.0012 0.0012
Entamoeba histolytica hypothetical protein 0.0351 0.0743 0.2397
Echinococcus granulosus gamma secretase subunit aph 1 0.0246 0.0502 0.0502
Trichomonas vaginalis centrin, putative 0.0204 0.0404 0.112
Echinococcus granulosus survival motor neuron protein 1 0.025 0.051 0.051
Onchocerca volvulus 0.0092 0.0145 0.0303
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.126 0.2844 0.2838
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0032 0.0006 0.0006
Brugia malayi Papain family cysteine protease containing protein 0.1343 0.3036 0.3036
Trichomonas vaginalis set domain proteins, putative 0.0499 0.1086 0.3011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0351 0.0743 0.206
Echinococcus granulosus cathepsin L 0.0351 0.0743 0.0743
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.159 0.3606 0.9628
Echinococcus multilocularis calpain 0.126 0.2844 0.2844
Giardia lamblia Alanyl dipeptidyl peptidase 0.0198 0.0388 0.1006
Schistosoma mansoni cathepsin C 0.0351 0.0743 0.0743
Giardia lamblia Alanyl dipeptidyl peptidase 0.0198 0.0388 0.1006
Trypanosoma brucei calpain-like protein, putative 0.126 0.2844 0.759
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1343 0.3036 0.842
Leishmania major hypothetical protein, conserved 0.0204 0.0404 0.1058
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0198 0.0388 0.1037
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0063 0.0079 0.0079
Echinococcus granulosus Thymidine kinase 2 mitochondrial 0.0323 0.0679 0.0679
Schistosoma mansoni cathepsin F (C01 family) 0.1343 0.3036 0.3036
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0373 0.0794 0.2102
Entamoeba histolytica prolyl oligopeptidase family protein 0.0198 0.0388 0.1222
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0032 0.0006 0.0006
Plasmodium falciparum plasmepsin IX 0.0109 0.0185 0.0608
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0351 0.0743 0.0743
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0373 0.0794 0.2201
Plasmodium falciparum serine repeat antigen 4 0.0351 0.0743 0.2446
Echinococcus granulosus dnaJ subfamily B 0.0409 0.0877 0.0877
Trypanosoma brucei oligopeptidase b 0.0673 0.1486 0.3956
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0351 0.0743 0.2397
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0351 0.0743 0.0743
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0117 0.0202 0.0202
Toxoplasma gondii centrin 0.0204 0.0404 0.1079
Trypanosoma cruzi major cysteine proteinase, putative 0.0449 0.0971 0.0963
Trichomonas vaginalis thymidine kinase, putative 0.0257 0.0526 0.1458
Echinococcus granulosus Dipeptidyl peptidase 9 0.0286 0.0593 0.0593
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0198 0.0388 0.1222
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0009 0.0009
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0092 0.0145 0.0145
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0351 0.0743 0.206
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0351 0.0743 0.2446
Schistosoma mansoni calpain (C02 family) 0.126 0.2844 0.2844
Brugia malayi Papain family cysteine protease containing protein 0.0758 0.1682 0.1682
Schistosoma mansoni aldehyde dehydrogenase 0.0128 0.0227 0.0227
Schistosoma mansoni cathepsin s 0.0407 0.0872 0.0872
Brugia malayi carbohydrate phosphorylase 0.0106 0.0177 0.0177
Brugia malayi calcium-binding protein 0.0204 0.0404 0.0404
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.004 0.0025 0.0025
Brugia malayi calpain family protein 1 0.3356 0.7685 0.7685
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0351 0.0743 0.206
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0032 0.0006 0.0006
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0351 0.0743 0.0743
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.0225 0.0452 0.1434
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0089 0.0137 0.0137
Brugia malayi Cytochrome P450 family protein 0.0033 0.0009 0.0009
Trichomonas vaginalis thymidine kinase, putative 0.0257 0.0526 0.1458
Echinococcus multilocularis programmed cell death protein 0.0208 0.0413 0.0413
Echinococcus granulosus caspase 3 0.1111 0.2498 0.2498
Trichomonas vaginalis conserved hypothetical protein 0.0351 0.0743 0.206
Leishmania major hypothetical protein, conserved 0.0208 0.0413 0.1081
Brugia malayi hypothetical protein 0.004 0.0025 0.0025
Echinococcus multilocularis glycogen phosphorylase 0.0106 0.0177 0.0177
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.126 0.2844 0.759
Loa Loa (eye worm) hypothetical protein 0.0168 0.032 0.032
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0061 0.0072 0.0072
Plasmodium vivax aspartyl protease, putative 0.0109 0.0185 0.0608
Loa Loa (eye worm) RGS-3 protein 0.004 0.0025 0.0025
Schistosoma mansoni cpg binding protein 0.003 0.0002 0.0002
Giardia lamblia Cathepsin B precursor 0.0351 0.0743 0.1997
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0351 0.0743 0.1997
Plasmodium falciparum serine repeat antigen 7 0.0351 0.0743 0.2446
Schistosoma mansoni hypothetical protein 0.0077 0.0111 0.0111
Echinococcus granulosus EF HAND 1 calcium binding site 0.0204 0.0404 0.0404
Schistosoma mansoni aldo-keto reductase 0.0092 0.0145 0.0145
Trichomonas vaginalis esterase, putative 0.0035 0.0012 0.0034
Entamoeba histolytica cysteine protease, putative 0.0758 0.1682 0.5512
Echinococcus multilocularis cathepsin L 0.0758 0.1682 0.1682
Trypanosoma brucei prolyl oligopeptidase, putative 0.0673 0.1486 0.3956
Trypanosoma cruzi calmodulin, putative 0.0204 0.0404 0.0396
Trypanosoma brucei Calpain-like protein 1.2 0.0373 0.0794 0.2102
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0351 0.0743 0.0743
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0093 0.0084
Schistosoma mansoni cercarial elastase (S01 family) 0.0077 0.0111 0.0111
Echinococcus multilocularis aldo keto reductase 0.0092 0.0145 0.0145
Echinococcus granulosus importin subunit beta 1 0.0033 0.0008 0.0008
Loa Loa (eye worm) MH2 domain-containing protein 0.0118 0.0204 0.0204
Echinococcus granulosus glycogen phosphorylase 0.0106 0.0177 0.0177
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0092 0.0145 0.0145
Brugia malayi Animal haem peroxidase family protein 0.0168 0.032 0.032
Entamoeba histolytica calmodulin, putative 0.0204 0.0404 0.1274
Plasmodium vivax proteasome subunit beta type-2, putative 0.0042 0.0029 0.0094
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0092 0.0145 0.0145
Trypanosoma brucei mitochondrial calcium uptake 1 0.0204 0.0404 0.106
Entamoeba histolytica calcium-binding protein, putative 0.0204 0.0404 0.1274
Echinococcus multilocularis transcription factor Dp 1 0.004 0.0025 0.0025
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0046 0.0038 0.0078
Schistosoma mansoni axis inhibition protein axin 0.004 0.0025 0.0025
Schistosoma mansoni deoxyuridine 5'-triphosphate nucleotidohydrolase 0.0153 0.0285 0.0285
Plasmodium vivax serine-repeat antigen (SERA) 0.0351 0.0743 0.2446
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0032 0.0006 0.0006
Trichomonas vaginalis calmodulin, putative 0.0204 0.0404 0.112
Echinococcus multilocularis enteropeptidase 0.0077 0.0111 0.0111
Toxoplasma gondii HEAT repeat-containing protein 0.0033 0.0008 0.0022
Echinococcus multilocularis cysteine protease 0.1343 0.3036 0.3036
Loa Loa (eye worm) cysteine protease 0.1343 0.3036 0.3036
Brugia malayi cathepsin Z-like cysteine proteinase 0.0351 0.0743 0.0743
Trypanosoma brucei calpain-like protein, putative 0.126 0.2844 0.759
Echinococcus multilocularis axis inhibition protein axin 0.004 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0032 0.0006 0.0006
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.126 0.2844 0.2838
Onchocerca volvulus Huntingtin homolog 0.0121 0.0211 0.0442
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0351 0.0743 0.206
Onchocerca volvulus 0.0092 0.0145 0.0303
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0351 0.0743 0.0743
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0373 0.0794 0.0786
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0373 0.0794 0.2101
Loa Loa (eye worm) oxidoreductase 0.0092 0.0145 0.0145
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0373 0.0794 0.2201
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.1035 0.2324 0.2318
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0758 0.1682 0.4481
Entamoeba histolytica glycogen phosphorylase, putative 0.0046 0.0038 0.0061
Toxoplasma gondii ABC1 family protein 0.0035 0.0012 0.0033
Brugia malayi calpain D 0.0373 0.0794 0.0794
Trichomonas vaginalis aldo-keto reductase, putative 0.0092 0.0145 0.0401
Schistosoma mansoni hypothetical protein 0.0421 0.0905 0.0905
Trypanosoma brucei Calpain-like protein 1.1 0.0373 0.0794 0.2102
Brugia malayi hypothetical protein 0.0038 0.002 0.002
Brugia malayi hypothetical protein 0.0121 0.0211 0.0211
Onchocerca volvulus Chorion peroxidase homolog 0.0168 0.032 0.067
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0025 0.0069
Plasmodium falciparum serine repeat antigen 5 0.0351 0.0743 0.2446
Brugia malayi Cathepsin L-like precursor 0.1343 0.3036 0.3036
Entamoeba histolytica cysteine protease, putative 0.0758 0.1682 0.5512
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1343 0.3036 0.842
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0286 0.0593 0.1566
Loa Loa (eye worm) hypothetical protein 0.165 0.3745 0.3745
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1343 0.3036 0.842
Brugia malayi Peroxidasin 0.0168 0.032 0.032
Onchocerca volvulus Peroxidase homolog 0.0168 0.032 0.067
Echinococcus multilocularis dnaJ subfamily B 0.0409 0.0877 0.0877
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0079 0.0079
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.002 0.002
Echinococcus multilocularis cysteine protease 0.1343 0.3036 0.3036
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0204 0.0404 0.112
Entamoeba histolytica cysteine protease, putative 0.0758 0.1682 0.5512
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0373 0.0794 0.0786
Entamoeba histolytica cysteine proteinase 2 0.0758 0.1682 0.5512
Loa Loa (eye worm) hypothetical protein 0.004 0.0025 0.0025
Trypanosoma brucei protein I/6 0.0204 0.0404 0.106
Echinococcus multilocularis regulator of G protein signaling 0.004 0.0025 0.0025
Chlamydia trachomatis glycogen phosphorylase 0.0106 0.0177 0.5327
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0204 0.0404 0.1331
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0117 0.0202 0.0202
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0006 0.0006
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0092 0.0145 0.0145
Trypanosoma cruzi Aph-1 protein, putative 0.0096 0.0154 0.0145
Echinococcus granulosus histone lysine methyltransferase setb 0.0063 0.0079 0.0079
Trypanosoma brucei RNA helicase, putative 0.0818 0.1822 0.4854
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.4357 1 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0439 0.0946 0.0946
Loa Loa (eye worm) hypothetical protein 0.025 0.051 0.051
Loa Loa (eye worm) blistered cuticle protein 3 0.0168 0.032 0.032
Entamoeba histolytica aldose reductase, putative 0.0092 0.0145 0.0415
Entamoeba histolytica aldose reductase, putative 0.0092 0.0145 0.0415
Echinococcus granulosus expressed protein 0.0782 0.1739 0.1739
Schistosoma mansoni caspase-7 (C14 family) 0.1833 0.4167 0.4167
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.007 0.0093 0.0093
Schistosoma mansoni steroid hormone receptor ad4bp 0.0032 0.0006 0.0006
Brugia malayi PXA domain containing protein 0.004 0.0025 0.0025
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.0225 0.0452 0.1434
Schistosoma mansoni centrin-related 0.0204 0.0404 0.0404
Giardia lamblia Hypothetical protein 0.0351 0.0743 0.1997
Onchocerca volvulus 0.1343 0.3036 0.6361
Echinococcus granulosus aldehyde reductase 0.0065 0.0083 0.0083
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0012 0.0025
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0056 0.0061 0.027
Trypanosoma brucei hypothetical protein, conserved 0.0204 0.0404 0.106
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1442 0.3264 0.8713
Echinococcus granulosus NADH ubiquinone oxidoreductase 42 kDa subunit 0.0072 0.0099 0.0099
Leishmania major cathepsin L-like protease 0.1442 0.3264 0.8713
Brugia malayi Calmodulin-like protein 0.0204 0.0404 0.0404
Schistosoma mansoni cathepsin F (C01 family) 0.1343 0.3036 0.3036
Onchocerca volvulus Prolyl endopeptidase homolog 0.165 0.3745 0.7846
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0128 0.0227 0.0227
Entamoeba histolytica cysteine proteinase, putative 0.0758 0.1682 0.5512
Echinococcus granulosus neurocalcin 0.0204 0.0404 0.0404
Brugia malayi hypothetical protein 0.0077 0.0111 0.0111
Echinococcus granulosus transcription factor Dp 1 0.004 0.0025 0.0025
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0198 0.0388 0.0388
Plasmodium falciparum metacaspase 1 0.0722 0.1601 0.5272
Loa Loa (eye worm) hypothetical protein 0.0407 0.0872 0.0872
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0351 0.0743 0.206
Loa Loa (eye worm) oxidoreductase 0.0092 0.0145 0.0145
Leishmania major metacaspase, putative 0.0722 0.1601 0.4261
Brugia malayi Cathepsin L-like precursor 0.0407 0.0872 0.0872
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0012 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0722 0.1601 0.4439
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1442 0.3264 0.8713
Trypanosoma cruzi aldo-keto reductase 0.0092 0.0145 0.0136
Trypanosoma cruzi 20S proteasome subunit 0.0042 0.0029 0.002
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0373 0.0794 0.0786
Loa Loa (eye worm) animal heme peroxidase 0.0168 0.032 0.032
Echinococcus multilocularis thymidine kinase 0.0323 0.0679 0.0679
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0351 0.0743 0.0743
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.356 0.8157 0.8157
Echinococcus multilocularis caspase 0.1833 0.4167 0.4167
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1343 0.3036 0.842
Plasmodium vivax deoxyuridine 5'-triphosphate nucleotidohydrolase, putative 0.0153 0.0285 0.0939
Onchocerca volvulus 0.0092 0.0145 0.0303
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0092 0.0145 0.0145
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0758 0.1682 0.4481
Schistosoma mansoni hypothetical protein 0.0204 0.0404 0.0404
Entamoeba histolytica calpain large subunit domain III containing protein 0.0888 0.1983 0.6507
Schistosoma mansoni hypothetical protein 0.0373 0.0794 0.0794
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0204 0.0404 0.0404
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1343 0.3036 0.842
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1343 0.3036 0.3036
Loa Loa (eye worm) hypothetical protein 0.0032 0.0006 0.0006
Mycobacterium ulcerans oxidoreductase 0.0092 0.0145 0.0921
Echinococcus multilocularis expressed protein 0.0782 0.1739 0.1739
Brugia malayi Cathepsin L-like precursor 0.1343 0.3036 0.3036
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.126 0.2844 0.2838
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0204 0.0404 0.106
Loa Loa (eye worm) hypothetical protein 0.4357 1 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0373 0.0794 0.0786
Trypanosoma brucei caltractin, putative 0.0208 0.0413 0.1083
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.126 0.2844 0.2838
Echinococcus multilocularis aldo keto reductase 0.0092 0.0145 0.0145
Onchocerca volvulus 0.0421 0.0905 0.1896
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0758 0.1682 0.1682
Plasmodium falciparum cysteine proteinase falcipain 1 0.0758 0.1682 0.5541
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.0061 0.0169
Echinococcus granulosus Glycosyl transferase family 35 0.0106 0.0177 0.0177
Schistosoma mansoni memapsin-2 (A01 family) 0.0462 0.1 0.1
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0025 0.0069
Leishmania major calmodulin, putative 0.0204 0.0404 0.1058
Loa Loa (eye worm) hypothetical protein 0.0168 0.032 0.032
Echinococcus multilocularis EF hand domain containing family member A2 0.0208 0.0413 0.0413
Schistosoma mansoni caspase-3 (C14 family) 0.1833 0.4167 0.4167
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0351 0.0744 0.0744
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0373 0.0794 0.0786
Entamoeba histolytica grainin 2 0.0208 0.0413 0.1303
Echinococcus granulosus thymidine kinase 0.0323 0.0679 0.0679
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0351 0.0743 0.2446
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0208 0.0413 0.0404
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0722 0.1601 0.4439
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0378 0.0806 0.0806
Echinococcus multilocularis importin subunit beta 1 0.0033 0.0008 0.0008
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1343 0.3036 1
Entamoeba histolytica cysteine protease, putative 0.0351 0.0743 0.2397
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1442 0.3264 0.8713
Schistosoma mansoni lozenge 0.0059 0.0067 0.0067
Plasmodium vivax SET domain protein, putative 0.0063 0.0079 0.0259
Entamoeba histolytica hypothetical protein 0.0072 0.0099 0.0264
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0204 0.0404 0.1274
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0087 0.0133 0.0133
Mycobacterium ulcerans aldehyde dehydrogenase 0.0128 0.0227 0.148
Plasmodium vivax vivapain-1 0.0758 0.1682 0.5541
Schistosoma mansoni calpain C (C02 family) 0.126 0.2844 0.2844
Leishmania major hypothetical protein, conserved 0.0373 0.0794 0.2101
Trichomonas vaginalis glycogen phosphorylase, putative 0.0106 0.0177 0.0492
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0077 0.0111 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0025 0.0069
Trypanosoma brucei Calpain-like protein 2 0.0373 0.0794 0.2102
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0722 0.1601 0.4439
Giardia lamblia Cysteine protease 0.0351 0.0743 0.1997
Entamoeba histolytica cysteine proteinase 1, putative 0.0758 0.1682 0.5512
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.126 0.2844 0.2838
Echinococcus granulosus hypothetical protein 0.0092 0.0145 0.0145
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0032 0.0006 0.0006
Entamoeba histolytica hypothetical protein 0.0072 0.0099 0.0264
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0351 0.0743 0.206
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0092 0.0145 0.0145
Brugia malayi Papain family cysteine protease containing protein 0.0351 0.0743 0.0743
Trypanosoma cruzi prolyl endopeptidase 0.165 0.3745 0.3739
Loa Loa (eye worm) calmodulin-like protein 0.0204 0.0404 0.0404
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0012 0.0034
Giardia lamblia Cysteine protease 0.0351 0.0743 0.1997
Plasmodium vivax vivapain-3 0.0758 0.1682 0.5541
Onchocerca volvulus Peroxidasin homolog 0.0168 0.032 0.067
Schistosoma mansoni serine/threonine protein kinase 0.004 0.0025 0.0025
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0351 0.0743 0.0743
Trichomonas vaginalis glycogen phosphorylase, putative 0.0106 0.0177 0.0492
Trichomonas vaginalis aldo-keto reductase, putative 0.0092 0.0145 0.0401
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0351 0.0743 0.0743
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1343 0.3036 0.842
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0032 0.0006 0.0006
Echinococcus granulosus caspase 8 0.0722 0.1601 0.1601
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0025 0.0069
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0065 0.0082 0.0082
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0351 0.0743 0.0743
Onchocerca volvulus 0.0051 0.005 0.0105
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.126 0.2844 0.759
Schistosoma mansoni z-protein (S1r protein) 0.004 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0035 0.0012 0.0012

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 166 nM Inhibitory concentration against human MCH-R1-stimulated [Ca2+] influx ChEMBL. 16005225
IC50 (binding) = 166 nM Inhibitory concentration against human MCH-R1-stimulated [Ca2+] influx ChEMBL. 16005225
Ki (binding) = 3.1 nM Binding affinity towards human MCH-R1 evaluated by its ability to displace radioligand [125I]-Tyr13]-MCH ChEMBL. 16005225
Ki (binding) = 3.1 nM Binding affinity towards human MCH-R1 evaluated by its ability to displace radioligand [125I]-Tyr13]-MCH ChEMBL. 16005225

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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