Detailed information for compound 34594

Basic information

Technical information
  • TDR Targets ID: 34594
  • Name: prop-2-ynal
  • MW: 54.0474 | Formula: C3H2O
  • H donors: 0 H acceptors: 1 LogP: 0.2 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1


Substructure search Similarity search

Network

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Synonyms

  • 2-propynal
  • propiolaldehyde
  • 624-67-9
  • 2-Propyn-1-al
  • C05985
  • HC.equiv.CCHO
  • HC.$.CCHO
  • 4-01-00-03537 (Beilstein Handbook Reference)
  • BRN 1098318
  • EINECS 210-857-4
  • PROPYNAL
  • Propargylaldehyde
  • Propioaldehyde
  • Propiolaldehye
  • Propyn-3-al

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0008 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0014 0.0107 0.0243
Entamoeba histolytica protein kinase, putative 0.0016 0.0142 0.0801
Echinococcus multilocularis smad 0.0008 0.0026 0.0011
Brugia malayi neuropeptide F receptor 0.0067 0.089 0.3391
Schistosoma mansoni opsin-like receptor 0.0067 0.089 0.2076
Plasmodium falciparum cysteine repeat modular protein 3 0.0014 0.0107 0.1329
Brugia malayi Cyclin, N-terminal domain containing protein 0.0014 0.012 0.0446
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0196 0.0455
Trichomonas vaginalis cyclin D, putative 0.006 0.0785 0.4851
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0067 0.089 0.3391
Plasmodium vivax cyclin 4, putative 0.0014 0.012 0.0785
Schistosoma mansoni amine GPCR 0.0067 0.089 0.2076
Brugia malayi cyclin fold protein 1 variant b 0.0014 0.012 0.0446
Echinococcus granulosus dna polymerase eta 0.0021 0.0214 0.0201
Toxoplasma gondii GCC2 and GCC3 domain-containing protein 0.0014 0.0107 0.07
Echinococcus granulosus cyclin y 0.0014 0.012 0.0106
Loa Loa (eye worm) hypothetical protein 0.001 0.006 0.0133
Giardia lamblia Cyclin A 0.006 0.0785 0.4888
Trypanosoma cruzi cyclin, putative 0.0115 0.1603 1
Brugia malayi cytochrome P450 0.0008 0.0021 0.0066
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0196 0.0736
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0008 0.0024 0.0058
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0007 0.0015 0.0072
Entamoeba histolytica cell division protein kinase 2, putative 0.0049 0.0623 0.3831
Loa Loa (eye worm) hypothetical protein 0.0014 0.0107 0.0243
Plasmodium falciparum cysteine repeat modular protein 4 0.0014 0.0107 0.1329
Mycobacterium tuberculosis Conserved protein 0.0108 0.1488 0.1488
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Plasmodium vivax cysteine repeat modular protein 2, putative 0.0014 0.0107 0.07
Schistosoma mansoni hypothetical protein 0.0067 0.089 0.2076
Brugia malayi hypothetical protein 0.0067 0.089 0.3391
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0008 0.0021 0.0021
Echinococcus granulosus g protein coupled receptor 0.0067 0.089 0.0883
Echinococcus multilocularis G1:S specific cyclin D1 0.0014 0.012 0.0106
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0196 0.0736
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.006 0.0217
Onchocerca volvulus 0.0067 0.089 0.5351
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0008 0.0021 0.0021
Brugia malayi Pyruvate kinase, M2 isozyme 0.0036 0.0438 0.1661
Brugia malayi hypothetical protein 0.001 0.006 0.0217
Schistosoma mansoni cyclins 0.006 0.0785 0.1831
Echinococcus multilocularis rhodopsin orphan GPCR 0.0067 0.089 0.0883
Leishmania major cytochrome p450-like protein 0.0008 0.0021 0.0108
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0298 0.4285 1
Onchocerca volvulus 0.0026 0.0292 0.1693
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0318 0.1969
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0196 0.0455
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0196 0.0736
Echinococcus multilocularis netrin receptor unc 5 0.0016 0.0136 0.0123
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0008 0.0021 0.0116
Brugia malayi cell division control protein 2 homolog 0.0049 0.0623 0.2371
Mycobacterium ulcerans acyl-CoA synthetase 0.0007 0.0015 0.0077
Brugia malayi glutathione reductase 0.0047 0.0591 0.2248
Onchocerca volvulus Huntingtin homolog 0.0119 0.165 1
Echinococcus granulosus ephrin type A receptor 4 A 0.0071 0.0952 0.0945
Schistosoma mansoni neuropeptide receptor 0.0067 0.089 0.2076
Echinococcus granulosus cyclin B 0.0115 0.1603 0.1602
Entamoeba histolytica Ran family GTPase 0.0021 0.021 0.1229
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0008 0.0021 0.0116
Echinococcus granulosus hyperpolarization activated cyclic 0.0008 0.0024 0.0009
Trypanosoma brucei cyclin 9 0.0014 0.012 0.0729
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0008 0.0021 0.0108
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0067 0.089 0.2076
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0196 0.0736
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0008 0.0026 0.0011
Loa Loa (eye worm) hypothetical protein 0.0108 0.1488 0.3467
Toxoplasma gondii cyclin 4, putative 0.0014 0.012 0.0785
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0145 0.0885
Schistosoma mansoni hypothetical protein 0.0014 0.012 0.0279
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0214 0.132
Echinococcus multilocularis rhodopsin orphan GPCR 0.0067 0.089 0.0883
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0179 0.0179
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0067 0.089 0.2076
Loa Loa (eye worm) hypothetical protein 0.0007 0.0015 0.0027
Schistosoma mansoni cytochrome P450 0.0008 0.0021 0.0047
Loa Loa (eye worm) hypothetical protein 0.0009 0.0044 0.0095
Giardia lamblia Kinase, CMGC CDK 0.0049 0.0623 0.3875
Schistosoma mansoni biogenic amine receptor 0.0067 0.089 0.2076
Leishmania major hypothetical protein, conserved 0.0108 0.1488 0.9279
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0067 0.089 0.0883
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.021 0.1392
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0145 0.0131
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0067 0.089 0.0883
Loa Loa (eye worm) hypothetical protein 0.0108 0.1488 0.3467
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0214 0.0201
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0196 0.0182
Schistosoma mansoni lamin 0.0026 0.0292 0.068
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0623 0.1453
Trichomonas vaginalis STE family protein kinase 0.0037 0.0449 0.2731
Giardia lamblia Kinase, CMGC CDK 0.0049 0.0623 0.3875
Loa Loa (eye worm) hypothetical protein 0.0014 0.0107 0.0243
Entamoeba histolytica cysteine-rich surface protein, putative 0.0014 0.0107 0.0582
Loa Loa (eye worm) CYP4Cod1 0.0008 0.0021 0.004
Schistosoma mansoni ankyrin 23/unc44 0.0016 0.0136 0.0317
Loa Loa (eye worm) TK/EPH protein kinase 0.0073 0.0982 0.2285
Plasmodium falciparum pyruvate kinase 2 0.0019 0.018 0.2259
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0007 0.0015 0.0015
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0067 0.089 0.0883
Brugia malayi Cyclic-nucleotide gated cation channel 0.0008 0.0024 0.0079
Echinococcus multilocularis endonuclease reverse transcriptase 0.0014 0.0107 0.0093
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0067 0.089 0.2076
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0037 0.0449 0.0438
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0214 0.0499
Plasmodium vivax pyruvate kinase 2, putative 0.0019 0.018 0.119
Brugia malayi AKH receptor 0.0067 0.089 0.3391
Echinococcus granulosus cyclin A3 4 0.0014 0.012 0.0106
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0009 0.0044 0.0029
Brugia malayi nuclear receptor NHR-88 0.0009 0.0044 0.0155
Loa Loa (eye worm) hypothetical protein 0.0008 0.0024 0.0048
Loa Loa (eye worm) hypothetical protein 0.0115 0.1603 0.3736
Loa Loa (eye worm) hypothetical protein 0.0013 0.0093 0.021
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.001 0.006 0.0133
Mycobacterium ulcerans acyl-CoA synthetase 0.0007 0.0015 0.0077
Entamoeba histolytica pyruvate kinase, putative 0.0025 0.0277 0.1653
Loa Loa (eye worm) pyruvate kinase 0.0008 0.002 0.0038
Brugia malayi MH2 domain containing protein 0.0117 0.1632 0.6231
Trypanosoma cruzi cytochrome P450, putative 0.0008 0.0021 0.0108
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0093 0.0079
Mycobacterium ulcerans acyl-CoA synthetase 0.0007 0.0015 0.0077
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0049 0.0623 0.1448
Brugia malayi Melatonin receptor type 1A 0.0067 0.089 0.3391
Echinococcus multilocularis neuropeptide receptor 0.0067 0.089 0.0883
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Onchocerca volvulus 0.0067 0.089 0.5351
Brugia malayi nuclear hormone receptor family member nhr-6 0.0009 0.0044 0.0155
Leishmania major GTP-binding protein, putative 0.0021 0.021 0.1292
Echinococcus multilocularis pyruvate kinase 0.0019 0.018 0.0167
Echinococcus multilocularis Smad4 0.0008 0.0026 0.0011
Toxoplasma gondii pyruvate kinase PyKII 0.0019 0.018 0.119
Onchocerca volvulus 0.0067 0.089 0.5351
Schistosoma mansoni DNA polymerase eta 0.0021 0.0214 0.0499
Echinococcus granulosus snurportin 1 0.0298 0.4285 0.4308
Echinococcus multilocularis hyperpolarization activated cyclic 0.0008 0.0024 0.0009
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0008 0.0021 0.0021
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0196 0.1106
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0008 0.0021 0.0021
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0067 0.089 0.0883
Mycobacterium leprae Probable pyruvate kinase PykA 0.0036 0.0438 0.2602
Loa Loa (eye worm) MH1 domain-containing protein 0.0008 0.0026 0.0052
Loa Loa (eye worm) hypothetical protein 0.0009 0.0044 0.0095
Echinococcus granulosus 3'partial|serine:threonine protein kinase PAK 2 0.0015 0.013 0.0116
Echinococcus granulosus cyclins 0.006 0.0785 0.0777
Brugia malayi nuclear receptor RXR 0.0009 0.0044 0.0155
Brugia malayi Cyclin, N-terminal domain containing protein 0.0014 0.012 0.0446
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0214 0.132
Toxoplasma gondii cyclin domain protein, cyclin H family protein 0.0014 0.012 0.0785
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0008 0.0024 0.0009
Echinococcus granulosus dna polymerase kappa 0.0021 0.0214 0.0201
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0067 0.089 0.207
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0145 0.0885
Loa Loa (eye worm) hypothetical protein 0.001 0.006 0.0133
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0214 0.1423
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0547 0.1276
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.0145 0.0954
Loa Loa (eye worm) hypothetical protein 0.0028 0.0318 0.0736
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0015 0.0044
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0008 0.0021 0.0116
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0196 0.0455
Trichomonas vaginalis penicillin-binding protein, putative 0.0108 0.1488 0.9274
Entamoeba histolytica protein kinase, putative 0.0014 0.0119 0.0657
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0196 0.0736
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0014 0.012 0.0106
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0008 0.0021 0.0021
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0008 0.0021 0.0116
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0196 0.0182
Loa Loa (eye worm) cyclin domain-containing protein 0.0014 0.012 0.0272
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0318 0.2122
Giardia lamblia G2/mitotic-specific cyclin B 0.0115 0.1603 1
Echinococcus multilocularis nuclear receptor nhr 48 0.0009 0.0044 0.0029
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0049 0.0623 0.4176
Brugia malayi G-protein coupled receptor 0.0067 0.089 0.3391
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0271 0.1674
Trichomonas vaginalis penicillin-binding protein, putative 0.0108 0.1488 0.9274
Onchocerca volvulus 0.0067 0.089 0.5351
Echinococcus granulosus tm gpcr rhodopsin 0.0067 0.089 0.0883
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0569 0.0559
Brugia malayi beta-lactamase family protein 0.0108 0.1488 0.5678
Brugia malayi Cyclin, N-terminal domain containing protein 0.0014 0.012 0.0446
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0145 0.0954
Schistosoma mansoni pyruvate kinase 0.0036 0.0438 0.102
Mycobacterium tuberculosis Probable lipase LipE 0.0108 0.1488 0.1488
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0271 0.1578
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0196 0.0736
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0036 0.0438 0.0438
Brugia malayi Cyclin C 0.0014 0.012 0.0446
Schistosoma mansoni pyruvate kinase 0.0036 0.0438 0.102
Trichomonas vaginalis cyclin B, putative 0.0115 0.1603 1
Loa Loa (eye worm) hypothetical protein 0.001 0.006 0.0133
Echinococcus multilocularis nuclear factor of activated T cells 5 0.008 0.1077 0.1071
Brugia malayi Cytochrome P450 family protein 0.0008 0.0021 0.0066
Mycobacterium ulcerans hypothetical protein 0.0025 0.0271 0.1804
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0569 0.1326
Echinococcus granulosus voltage gated potassium channel 0.0012 0.0078 0.0064
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0015 0.0044
Trypanosoma brucei unspecified product 0.0014 0.0119 0.0726
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0067 0.089 0.2076
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0196 0.0455
Onchocerca volvulus 0.0067 0.089 0.5351
Schistosoma mansoni protein kinase 0.0016 0.0142 0.033
Plasmodium vivax cysteine repeat modular protein 3, putative 0.0014 0.0107 0.07
Echinococcus granulosus netrin receptor unc 5 0.0016 0.0136 0.0123
Brugia malayi MH1 domain containing protein 0.0008 0.0026 0.0086
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0591 0.3674
Brugia malayi Uncoordinated protein 44 0.0016 0.0136 0.0509
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0145 0.181
Schistosoma mansoni neuropeptide receptor 0.0067 0.089 0.2076
Echinococcus granulosus hyperpolarization activated cyclic 0.0008 0.0024 0.0009
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Loa Loa (eye worm) hypothetical protein 0.0012 0.0086 0.0194
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0271 0.0271
Schistosoma mansoni smad1 5 8 and 0.0008 0.0026 0.0059
Brugia malayi putative neuropeptide receptor 0.0067 0.089 0.3391
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0196 0.0182
Toxoplasma gondii propionate-CoA ligase 0.0007 0.0015 0.0077
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0569 0.0559
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0214 0.132
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0008 0.0021 0.0116
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0214 0.132
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0271 0.1804
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0008 0.0024 0.0009
Loa Loa (eye worm) MH2 domain-containing protein 0.0008 0.0026 0.0052
Toxoplasma gondii hypothetical protein 0.0014 0.0107 0.07
Entamoeba histolytica cyclin family protein 0.006 0.0785 0.4851
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0049 0.0623 0.0614
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0424 0.0989
Plasmodium falciparum importin beta, putative 0.0028 0.0318 0.4028
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0008 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0009 0.0044 0.0095
Schistosoma mansoni cyclin G 0.0014 0.012 0.0279
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0007 0.0015 0.0077
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0569 0.0559
Trypanosoma brucei cytochrome P450, putative 0.0008 0.0021 0.0108
Schistosoma mansoni neuropeptide receptor 0.0067 0.089 0.2076
Brugia malayi GnHR receptor homolog 0.0067 0.089 0.3391
Leishmania major cytochrome p450-like protein 0.0008 0.0021 0.0108
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.021 0.0197
Loa Loa (eye worm) hypothetical protein 0.0018 0.0179 0.0411
Schistosoma mansoni smad1 5 8 and 0.0008 0.0026 0.0059
Brugia malayi nuclear receptor RXR 0.001 0.006 0.0217
Echinococcus granulosus serotonin receptor 0.0067 0.089 0.0883
Echinococcus granulosus beta LACTamase domain containing family member 0.0108 0.1488 0.1486
Loa Loa (eye worm) hypothetical protein 0.0016 0.0138 0.0315
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0008 0.0021 0.0021
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0196 0.0182
Loa Loa (eye worm) P21-Rho-binding domain-containing protein 0.0015 0.013 0.0296
Loa Loa (eye worm) hypothetical protein 0.0009 0.0044 0.0095
Toxoplasma gondii thioredoxin reductase 0.0047 0.0591 0.3959
Schistosoma mansoni thyroid hormone receptor 0.002 0.0196 0.0455
Trichomonas vaginalis cyclin B, putative 0.006 0.0785 0.4851
Brugia malayi serine/threonine-protein kinase PAK 7 0.0016 0.0142 0.053
Trichomonas vaginalis cyclin B, putative 0.0115 0.1603 1
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0007 0.0015 0.0027
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0009 0.0044 0.0029
Echinococcus granulosus g protein coupled receptor 0.0067 0.089 0.0883
Schistosoma mansoni hypothetical protein 0.0167 0.2355 0.5495
Mycobacterium ulcerans lipase LipD 0.0108 0.1488 1
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0106 0.1466 0.1466
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0008 0.0021 0.0021
Plasmodium falciparum pyruvate kinase 0.0036 0.0438 0.5554
Loa Loa (eye worm) melatonin receptor type 1A 0.0067 0.089 0.207
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0623 0.3831
Brugia malayi P21-Rho-binding domain containing protein 0.0015 0.013 0.0485
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0145 0.0885
Chlamydia trachomatis pyruvate kinase 0.0036 0.0438 1
Brugia malayi hypothetical protein 0.0009 0.0044 0.0155
Loa Loa (eye worm) oxidoreductase 0.0007 0.0015 0.0027
Echinococcus granulosus cyclins 0.006 0.0785 0.0777
Brugia malayi hypothetical protein 0.0067 0.089 0.3391
Brugia malayi hypothetical protein 0.0119 0.165 0.63
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0179 0.2252
Plasmodium falciparum cyclin 1 0.0014 0.012 0.1491
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0008 0.0021 0.0021
Onchocerca volvulus 0.0108 0.1488 0.9007
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0424 0.0413
Onchocerca volvulus 0.0067 0.089 0.5351
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0067 0.089 0.0883
Loa Loa (eye worm) cyclin domain-containing protein 0.0185 0.2618 0.6106
Trypanosoma cruzi pyruvate kinase 2, putative 0.0036 0.0438 0.2714
Echinococcus granulosus neural Wiskott Aldrich syndrome protein 0.0015 0.013 0.0116
Schistosoma mansoni wiskott-aldrich syndrome protein 0.0015 0.013 0.0302
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0022 0.0227 0.1335
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0009 0.0044 0.0029
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0196 0.0182
Onchocerca volvulus Pyruvate kinase homolog 0.0036 0.0438 0.2585
Loa Loa (eye worm) hypothetical protein 0.002 0.0196 0.0449
Loa Loa (eye worm) hypothetical protein 0.0036 0.0438 0.1014
Brugia malayi hypothetical protein 0.0067 0.089 0.3391
Mycobacterium tuberculosis Conserved protein 0.0108 0.1488 0.1488
Mycobacterium tuberculosis Probable hydrolase 0.0108 0.1488 0.1488
Trichomonas vaginalis cyclins, putative 0.0014 0.012 0.0662
Echinococcus granulosus neuropeptide s receptor 0.0067 0.089 0.0883
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0214 0.0201
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0008 0.0021 0.0116
Plasmodium vivax hypothetical protein, conserved 0.0014 0.0107 0.07
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0569 0.1326
Brugia malayi Cytochrome P450 family protein 0.0008 0.0021 0.0066
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0271 0.1024
Echinococcus multilocularis neuropeptides capa receptor 0.0067 0.089 0.0883
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0108 0.1488 0.1488
Echinococcus granulosus tm gpcr rhodopsin 0.0067 0.089 0.0883
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0007 0.0015 0.0077
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0179 0.1186
Loa Loa (eye worm) hypothetical protein 0.0119 0.165 0.3846
Echinococcus granulosus cyclin 0.0014 0.012 0.0106
Brugia malayi neuropeptide F receptor 0.0067 0.089 0.3391
Loa Loa (eye worm) hypothetical protein 0.002 0.0196 0.0449
Brugia malayi Importin beta-1 subunit 0.0028 0.0318 0.1205
Mycobacterium ulcerans acyl-CoA synthetase 0.0007 0.0015 0.0077
Loa Loa (eye worm) hypothetical protein 0.002 0.0196 0.0449
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0108 0.1488 0.3471
Onchocerca volvulus 0.0014 0.012 0.0643
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0009 0.0044 0.0101
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0008 0.0024 0.0055
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0591 0.0581
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.021 0.1292
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0007 0.0015 0.0072
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0067 0.089 0.207
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0037 0.0449 0.0438
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0009 0.0044 0.0029
Echinococcus granulosus mothers against decapentaplegic 5 0.0008 0.0026 0.0011
Loa Loa (eye worm) hypothetical protein 0.0025 0.0271 0.0625
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0067 0.089 0.5351
Onchocerca volvulus 0.0025 0.0271 0.1567
Giardia lamblia Cyclin fold protein 1, putative 0.0014 0.012 0.0729
Echinococcus multilocularis cyclin b3 0.006 0.0785 0.0777
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0271 0.1614
Toxoplasma gondii cytochrome p450 superfamily protein 0.0008 0.0021 0.0116
Echinococcus multilocularis orexin receptor type 2 0.0067 0.089 0.0883
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Echinococcus granulosus g protein coupled receptor 0.0067 0.089 0.0883
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0145 0.0885
Loa Loa (eye worm) hypothetical protein 0.0007 0.0015 0.0027
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0271 0.1614
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Echinococcus multilocularis g protein coupled receptor 0.0067 0.089 0.0883
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0008 0.0024 0.0009
Brugia malayi nuclear hormone receptor family member odr-7 0.0009 0.0044 0.0155
Schistosoma mansoni thyroid hormone receptor 0.002 0.0196 0.0455
Echinococcus granulosus Nuclear hormone receptor HR96 0.0009 0.0044 0.0029
Brugia malayi intermediate filament protein 0.0026 0.0292 0.1103
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.001 0.006 0.0046
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0196 0.0182
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0196 0.0736
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0196 0.0736
Echinococcus multilocularis allatostatin A receptor 0.0067 0.089 0.0883
Trichomonas vaginalis ran, putative 0.0021 0.021 0.1229
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0008 0.0021 0.0116
Trypanosoma cruzi p21-activated kinase 3, putative 0.0022 0.0227 0.1398
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0008 0.0021 0.0021
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0067 0.089 0.2076
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0145 0.5
Leishmania major acetyl-CoA synthetase, putative 0.0007 0.0015 0.0072
Schistosoma mansoni acetyl-CoA synthetase 0.0007 0.0015 0.0033
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0008 0.0021 0.0116
Schistosoma mansoni neuropeptide F-like receptor 0.0067 0.089 0.2076
Giardia lamblia Hypothetical protein 0.0014 0.012 0.0729
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0049 0.0623 0.1448
Loa Loa (eye worm) hypothetical protein 0.0009 0.0044 0.0095
Loa Loa (eye worm) cyclin C 0.0014 0.012 0.0272
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0016 0.0138 0.0322
Entamoeba histolytica deoxycytidyl transferase, putative 0.0021 0.0214 0.1257
Brugia malayi hypothetical protein 0.0009 0.0044 0.0155
Loa Loa (eye worm) nuclear hormone receptor 0.0009 0.0044 0.0095
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0271 0.1674
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0008 0.0021 0.0021
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0008 0.0024 0.0055
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.1632 0.3804
Trichomonas vaginalis cyclin B, putative 0.0115 0.1603 1
Mycobacterium tuberculosis Probable lipase LipD 0.0108 0.1488 0.1488
Brugia malayi pyruvate kinase, muscle isozyme 0.0008 0.002 0.0063
Echinococcus multilocularis rhodopsin orphan GPCR 0.0067 0.089 0.0883
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.0145 0.0145
Schistosoma mansoni importin beta-1 0.0028 0.0318 0.0742
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0214 0.132
Loa Loa (eye worm) G-protein coupled receptor 0.0067 0.089 0.207
Leishmania major trypanothione reductase 0.0047 0.0591 0.3674
Brugia malayi hypothetical protein 0.0014 0.012 0.0446
Loa Loa (eye worm) TYRA-2 protein 0.0067 0.089 0.207
Loa Loa (eye worm) hypothetical protein 0.01 0.1375 0.3203
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0196 0.0455
Echinococcus multilocularis neuropeptide FF receptor 2 0.0067 0.089 0.0883
Echinococcus granulosus pyruvate kinase 0.0019 0.018 0.0167
Mycobacterium ulcerans acetyl-CoA synthetase 0.0007 0.0015 0.0077
Plasmodium vivax pyruvate kinase, putative 0.0036 0.0438 0.2925
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0007 0.0015 0.0015
Echinococcus multilocularis serotonin receptor 0.0067 0.089 0.0883
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0591 0.1373
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0067 0.089 0.0883
Schistosoma mansoni coup transcription factor 0.002 0.0196 0.0455
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0067 0.089 0.0883
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0008 0.0021 0.0021
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0008 0.0021 0.0108
Schistosoma mansoni alpha-1 adrenergic receptor 0.0067 0.089 0.2076
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0008 0.0021 0.0116
Brugia malayi GCC2 and GCC3 family protein 0.0014 0.0107 0.0398
Brugia malayi hypothetical protein 0.0035 0.0424 0.1611
Schistosoma mansoni neuropeptide receptor 0.0067 0.089 0.2076
Onchocerca volvulus 0.002 0.0196 0.1106
Entamoeba histolytica hypothetical protein 0.0035 0.0424 0.2579
Echinococcus granulosus cyclin b3 0.006 0.0785 0.0777
Brugia malayi larval opioid receptor 0.0067 0.089 0.3391
Entamoeba histolytica cyclin family protein 0.006 0.0785 0.4851
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0196 0.0449
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0108 0.1488 0.5678
Brugia malayi nuclear hormone receptor 0.002 0.0196 0.0736
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0271 0.1674
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.001 0.006 0.0046
Loa Loa (eye worm) hypothetical protein 0.0025 0.0277 0.064
Echinococcus multilocularis pyruvate kinase 0.0028 0.0326 0.0314
Onchocerca volvulus 0.0067 0.089 0.5351
Brugia malayi P21-Rho-binding domain containing protein 0.0015 0.013 0.0485
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0214 0.132
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0196 0.0449
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0008 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Plasmodium vivax hypothetical protein, conserved 0.0014 0.012 0.0785
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0185 0.2618 0.2626
Echinococcus granulosus neuropeptide receptor 0.0067 0.089 0.0883
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0007 0.0015 0.0015
Entamoeba histolytica cyclin, domain containing protein 0.0014 0.012 0.0662
Echinococcus multilocularis neuropeptide Y receptor 0.0067 0.089 0.0883
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0118 0.164 0.164
Echinococcus multilocularis sex peptide receptor 0.0067 0.089 0.0883
Brugia malayi Protein kinase domain containing protein 0.0049 0.0623 0.2371
Toxoplasma gondii kringle domain-containing protein 0.0014 0.0107 0.07
Echinococcus multilocularis lamin 0.0026 0.0292 0.0279
Echinococcus multilocularis serotonin receptor 0.0067 0.089 0.0883
Echinococcus multilocularis rhodopsin orphan GPCR 0.0067 0.089 0.0883
Echinococcus granulosus cyclin dependent kinase 5 0.0049 0.0623 0.0614
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0009 0.0044 0.0177
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0214 0.132
Onchocerca volvulus 0.0009 0.0044 0.0177
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0008 0.0024 0.0048
Trypanosoma cruzi cyclin 6, putative 0.0115 0.1603 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0145 0.0885
Mycobacterium ulcerans acyl-CoA synthetase 0.0007 0.0015 0.0077
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0214 0.132
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0271 0.1804
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0196 0.0449
Schistosoma mansoni nuclear hormone receptor 0.0009 0.0044 0.0101
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0196 0.1106
Brugia malayi Cytochrome P450 family protein 0.0008 0.0021 0.0066
Brugia malayi ecdysteroid receptor 0.002 0.0196 0.0736
Loa Loa (eye worm) hypothetical protein 0.0009 0.0044 0.0095
Echinococcus granulosus alpha 1A adrenergic receptor 0.0067 0.089 0.0883
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0145 0.0885
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0067 0.089 0.2076
Loa Loa (eye worm) hypothetical protein 0.002 0.0196 0.0449
Trypanosoma brucei cdc2-related kinase 3 0.0049 0.0623 0.3875
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0145 0.0885
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0292 0.0674
Schistosoma mansoni nuclear hormone receptor 0.0009 0.0044 0.0101
Plasmodium falciparum conserved protein, unknown function 0.0014 0.0107 0.1329
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.021 0.0791
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0196 0.0455
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0008 0.0024 0.0055
Onchocerca volvulus 0.01 0.1375 0.8315
Trichomonas vaginalis cyclin B, putative 0.0014 0.012 0.0662
Echinococcus granulosus potassium voltage gated channel subfamily H 0.004 0.0494 0.0483
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0012 0.0078 0.0285
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0165 0.0165
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Trichomonas vaginalis cyclins, putative 0.0115 0.1603 1
Echinococcus multilocularis cyclins 0.006 0.0785 0.0777
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Echinococcus multilocularis cyclin G2 0.0014 0.012 0.0106
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0214 0.132
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0196 0.0449
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0106 0.1466 0.1466
Brugia malayi Protein kinase domain containing protein 0.0016 0.0148 0.0555
Schistosoma mansoni amine GPCR 0.0067 0.089 0.2076
Entamoeba histolytica cyclin, putative 0.0115 0.1603 1
Giardia lamblia Pyruvate kinase 0.0036 0.0438 0.2714
Leishmania major acetyl-CoA synthetase, putative 0.0007 0.0015 0.0072
Brugia malayi nuclear hormone receptor 0.0009 0.0044 0.0155
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0119 0.0726
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0292 0.1103
Echinococcus granulosus rhodopsin orphan GPCR 0.0067 0.089 0.0883
Brugia malayi G-protein coupled receptor 0.0067 0.089 0.3391
Schistosoma mansoni netrin receptor unc5 0.0016 0.0136 0.0317
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.004 0.0494 0.1875
Schistosoma mansoni cyclin G2 0.0014 0.012 0.0279
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0241 0.1422
Echinococcus multilocularis cyclin dependent kinase 1 0.0049 0.0623 0.0614
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0009 0.0044 0.0029
Trichomonas vaginalis pyruvate kinase, putative 0.0036 0.0438 0.2662
Loa Loa (eye worm) hypothetical protein 0.0014 0.0107 0.0243
Echinococcus multilocularis cyclin y 0.0014 0.012 0.0106
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0214 0.0201
Onchocerca volvulus 0.0067 0.089 0.5351
Loa Loa (eye worm) hypothetical protein 0.0009 0.0044 0.0095
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0007 0.0015 0.0027
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0271 0.1024
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0007 0.0015 0.0015
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0214 0.0493
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0067 0.089 0.0883
Trypanosoma cruzi cytochrome P450, putative 0.0008 0.0021 0.0108
Schistosoma mansoni DNA polymerase IV / kappa 0.0006 0.0003 0.0006
Toxoplasma gondii cyclin, N-terminal domain-containing protein 0.0014 0.012 0.0785
Loa Loa (eye worm) nuclear receptor NHR-67 0.0009 0.0044 0.0095
Echinococcus multilocularis neural Wiskott Aldrich syndrome protein 0.0015 0.013 0.0116
Echinococcus multilocularis g protein coupled receptor 0.0067 0.089 0.0883
Brugia malayi Dopamine receptor protein 1 0.0067 0.089 0.3391
Brugia malayi MH2 domain containing protein 0.0008 0.0026 0.0086
Trypanosoma cruzi mitotic cyclin, putative 0.0014 0.012 0.0729
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0455 0.2772
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.021 0.1292
Schistosoma mansoni neuropeptide f receptor 76f 0.0067 0.089 0.2076
Echinococcus granulosus cyclin dependent kinase 1 0.0049 0.0623 0.0614
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0214 0.1423
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0007 0.0015 0.0072
Echinococcus granulosus neuropeptides capa receptor 0.0067 0.089 0.0883
Schistosoma mansoni intermediate filament proteins 0.0026 0.0292 0.068
Echinococcus multilocularis tumor protein p63 0.0683 0.9928 1
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0437 0.2656
Echinococcus multilocularis voltage gated potassium channel 0.0012 0.0078 0.0064
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0241 0.1422
Mycobacterium leprae putative cytochrome p450 0.0008 0.0021 0.0035
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0145 0.0131
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0067 0.089 0.0883
Loa Loa (eye worm) hypothetical protein 0.0009 0.0044 0.0095
Trichomonas vaginalis STE family protein kinase 0.0037 0.0449 0.2731
Echinococcus granulosus endonuclease reverse transcriptase 0.0014 0.0107 0.0093
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.0145 0.0954
Brugia malayi hypothetical protein 0.0067 0.089 0.3391
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0214 0.132
Treponema pallidum NADH oxidase 0.0016 0.0145 0.5
Loa Loa (eye worm) cyclin domain-containing protein 0.0014 0.012 0.0272
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0196 0.0736
Onchocerca volvulus Huntingtin homolog 0.0119 0.165 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0271 0.1614
Onchocerca volvulus Netrin receptor homolog 0.0016 0.0136 0.0743
Schistosoma mansoni cellular tumor antigen P53 0.01 0.1375 0.3207
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0008 0.0021 0.0108
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0014 0.012 0.0106
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0623 0.3831
Echinococcus granulosus 7tm_1 domain containing protein 0.0067 0.089 0.0883
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0024 0.0055
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0067 0.089 0.207
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0119 0.0726
Mycobacterium tuberculosis Probable dehydrogenase 0.0106 0.1466 0.1466
Loa Loa (eye worm) cytochrome P450 family protein 0.0008 0.0021 0.004
Echinococcus multilocularis pyruvate kinase 0.0019 0.018 0.0167
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0067 0.089 0.2076
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0014 0.012 0.0279
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Mycobacterium tuberculosis Probable oxidoreductase 0.0118 0.164 0.164
Echinococcus multilocularis PAK box P21 Rho binding 0.0016 0.0142 0.0128
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0009 0.0044 0.0029
Loa Loa (eye worm) hypothetical protein 0.0018 0.0179 0.0411
Loa Loa (eye worm) hypothetical protein 0.0009 0.0044 0.0095
Brugia malayi conserved hypotetical protein 0.0009 0.0044 0.0155
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0067 0.089 0.0883
Echinococcus granulosus cyclin G2 0.0014 0.012 0.0106
Onchocerca volvulus 0.0026 0.0292 0.1693
Echinococcus granulosus rhodopsin orphan GPCR 0.0067 0.089 0.0883
Echinococcus granulosus cytochrome P450 2K1 0.0008 0.0021 0.0006
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0196 0.0736
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0196 0.0455
Trichomonas vaginalis STE family protein kinase 0.0037 0.0449 0.2731
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0008 0.0021 0.0116
Echinococcus multilocularis rhodopsin orphan GPCR 0.0067 0.089 0.0883
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0008 0.0024 0.0048
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Schistosoma mansoni hypothetical protein 0.0014 0.012 0.0279
Loa Loa (eye worm) hypothetical protein 0.0035 0.0416 0.0964
Giardia lamblia Pyruvate kinase 0.0019 0.018 0.1104
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0014 0.0107 0.07
Loa Loa (eye worm) hypothetical protein 0.002 0.0196 0.0449
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0271 0.1804
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0067 0.089 0.2076
Schistosoma mansoni amine GPCR 0.0067 0.089 0.2076
Echinococcus multilocularis g protein coupled receptor 0.0067 0.089 0.0883
Schistosoma mansoni biogenic amine receptor 0.0067 0.089 0.2076
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0196 0.0182
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0008 0.0021 0.0116
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0214 0.132
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0008 0.0021 0.0116
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0015 0.0015
Brugia malayi Dopamine receptor protein 2 0.0067 0.089 0.3391
Trypanosoma cruzi hypothetical protein, conserved 0.0108 0.1488 0.9279
Echinococcus granulosus cyclins 0.006 0.0785 0.0777
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Plasmodium falciparum glutathione reductase 0.0016 0.0145 0.181
Echinococcus multilocularis ephrin type A receptor 4 A 0.0071 0.0952 0.0945
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0214 0.132
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0214 0.0214
Brugia malayi Cyclin, N-terminal domain containing protein 0.0185 0.2618 1
Echinococcus granulosus orexin receptor type 2 0.0067 0.089 0.0883
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0145 0.0542
Brugia malayi follicle stimulating hormone receptor 0.0067 0.089 0.3391
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0067 0.089 0.0883
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0196 0.0182
Brugia malayi G protein-coupled receptor 0.0067 0.089 0.3391
Giardia lamblia Hypothetical protein 0.006 0.0785 0.4888
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0214 0.0808
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.021 0.2644
Echinococcus multilocularis somatostatin receptor 0.0067 0.089 0.0883
Echinococcus multilocularis snurportin 1 0.0298 0.4285 0.4308
Echinococcus multilocularis cyclin t1 0.0014 0.012 0.0106
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0214 0.132
Schistosoma mansoni voltage-gated potassium channel 0.0012 0.0078 0.018
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0145 0.0954
Onchocerca volvulus 0.0067 0.089 0.5351
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Echinococcus granulosus rhodopsin orphan GPCR 0.0067 0.089 0.0883
Plasmodium vivax glutathione reductase, putative 0.0047 0.0591 0.3959
Plasmodium falciparum cyclin 0.006 0.0785 1
Loa Loa (eye worm) hypothetical protein 0.0115 0.1603 0.3736
Leishmania major mitotic cyclin, putative 0.0014 0.012 0.0729
Giardia lamblia CEGP1 protein 0.0014 0.0107 0.065
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0008 0.0021 0.0116
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0196 0.0736
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0196 0.0182
Echinococcus granulosus rhodopsin orphan GPCR 0.0067 0.089 0.0883
Echinococcus multilocularis cyclins 0.006 0.0785 0.0777
Loa Loa (eye worm) cyclin fold protein 1 variant b 0.0014 0.012 0.0272
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0067 0.089 0.2076
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0007 0.0015 0.0072
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0145 0.0819
Echinococcus granulosus cyclin y 0.0014 0.012 0.0106
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0016 0.0136 0.0123
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0145 0.0885
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0008 0.0026 0.0059
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.1632 0.3804
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0196 0.0182
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0569 0.0559
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0082 0.0301
Echinococcus granulosus neuropeptide FF receptor 2 0.0067 0.089 0.0883
Onchocerca volvulus 0.0014 0.0107 0.0565
Schistosoma mansoni ephrin receptor 0.0058 0.0753 0.1756
Toxoplasma gondii cyclin dependent kinase binding protein 0.0014 0.012 0.0785
Plasmodium falciparum cyclin dependent kinase binding protein, putative 0.0014 0.012 0.1491
Toxoplasma gondii ABC1 family protein 0.0108 0.1488 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0196 0.0449
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0145 0.0885
Trypanosoma cruzi cyclin, putative 0.0115 0.1603 1
Mycobacterium ulcerans esterase/lipase LipP 0.0108 0.1488 1
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0009 0.0044 0.0101
Brugia malayi Thioredoxin reductase 0.0047 0.0591 0.2248
Entamoeba histolytica protein kinase, putative 0.0016 0.0142 0.0801
Echinococcus multilocularis cyclins 0.006 0.0785 0.0777
Leishmania major DNA polymerase kappa, putative 0.0021 0.0214 0.132
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0145 0.0885
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0007 0.0015 0.0015
Echinococcus multilocularis cyclin B 0.0115 0.1603 0.1602
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0145 0.0819
Trypanosoma cruzi DNA polymerase eta, putative 0.0021 0.0214 0.132
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0022 0.0227 0.0522
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0196 0.0182
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0214 0.132
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0037 0.0449 0.0438
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0008 0.0024 0.0009
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0569 0.1326
Entamoeba histolytica hypothetical protein 0.0014 0.0107 0.0582
Echinococcus granulosus rhodopsin orphan GPCR 0.0067 0.089 0.0883
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0067 0.089 0.0883
Echinococcus multilocularis Ankyrin 0.0016 0.0138 0.0125
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Brugia malayi sulfakinin receptor protein 0.0067 0.089 0.3391
Echinococcus multilocularis cyclin y 0.0014 0.012 0.0106
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0015 0.0044
Echinococcus multilocularis fmrfamide receptor 0.0067 0.089 0.0883
Leishmania major cytochrome p450-like protein 0.0008 0.0021 0.0108
Brugia malayi Smad1 0.0008 0.0026 0.0086
Brugia malayi ORL1-like opioid receptor 0.0067 0.089 0.3391
Echinococcus granulosus 7TM GPCR rhodopsin 0.0067 0.089 0.0883
Echinococcus multilocularis geminin 0.0167 0.2355 0.2361
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0145 0.181
Plasmodium falciparum glutathione reductase 0.0047 0.0591 0.7517
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0118 0.164 0.164
Giardia lamblia Hypothetical protein 0.0014 0.0107 0.065
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0067 0.089 0.207
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0145 0.0885
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0049 0.0623 0.1448
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0547 0.1276
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Loa Loa (eye worm) hypothetical protein 0.0026 0.0285 0.0657
Schistosoma mansoni cyclin B 0.0115 0.1603 0.374
Schistosoma mansoni hypothetical protein 0.0035 0.0424 0.0989
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0067 0.089 0.2076
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0145 0.0885
Loa Loa (eye worm) glutathione reductase 0.0047 0.0591 0.1373
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0007 0.0015 0.0077
Leishmania major pyruvate kinase 0.0036 0.0438 0.2714
Schistosoma mansoni neuropeptide F-like receptor 0.0067 0.089 0.2076
Brugia malayi nuclear receptor NHR-67 0.0009 0.0044 0.0155
Schistosoma mansoni zinc finger protein 0.0009 0.0044 0.0101
Entamoeba histolytica cyclin, putative 0.006 0.0785 0.4851
Loa Loa (eye worm) CYL-1 protein 0.0014 0.012 0.0272
Echinococcus granulosus pyruvate kinase 0.0019 0.018 0.0167
Trichomonas vaginalis D-aminoacylase, putative 0.0108 0.1488 0.9274
Schistosoma mansoni hypothetical protein 0.0167 0.2355 0.5495
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0008 0.0021 0.0021
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0011 0.0068 0.0249
Mycobacterium ulcerans acyl-CoA synthetase 0.0007 0.0015 0.0077
Trichomonas vaginalis cyclins, putative 0.007 0.0938 0.5811
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0145 0.0885
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0196 0.1106
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0008 0.0024 0.0009
Onchocerca volvulus 0.0009 0.0044 0.0177
Trichomonas vaginalis cyclin B3, putative 0.0014 0.012 0.0662
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.012 0.0662
Echinococcus granulosus smad 0.0008 0.0026 0.0011
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0009 0.0044 0.0177
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0007 0.0015 0.0077
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0271 0.1804
Echinococcus granulosus cyclin B3 1 0.006 0.0785 0.0777
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0196 0.0182
Trypanosoma brucei unspecified product 0.0021 0.0214 0.132
Schistosoma mansoni cyclin k 0.0014 0.012 0.0279
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0145 0.0885
Plasmodium falciparum protein kinase 5 0.0049 0.0623 0.7929
Schistosoma mansoni hypothetical protein 0.0067 0.089 0.2076
Schistosoma mansoni g1/s-specific cyclin C 0.0014 0.012 0.0279
Loa Loa (eye worm) hypothetical protein 0.002 0.0196 0.0449
Brugia malayi ephrin receptor 1 precursor 0.0027 0.0311 0.1177
Schistosoma mansoni hypothetical protein 0.0015 0.013 0.0302
Loa Loa (eye worm) hypothetical protein 0.0108 0.1488 0.3467
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0196 0.0182
Echinococcus multilocularis cyclins 0.006 0.0785 0.0777
Onchocerca volvulus 0.0067 0.089 0.5351
Schistosoma mansoni hypothetical protein 0.0015 0.013 0.0302
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0214 0.0214
Loa Loa (eye worm) hypothetical protein 0.0009 0.0044 0.0095
Echinococcus multilocularis cyclin B3 1 0.006 0.0785 0.0777
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0785 0.4851
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Giardia lamblia Cyclin B-like protein 0.0014 0.012 0.0729
Echinococcus multilocularis neuropeptide s receptor 0.0067 0.089 0.0883
Mycobacterium ulcerans pyruvate kinase 0.0036 0.0438 0.2925
Onchocerca volvulus 0.0108 0.1488 0.9007
Echinococcus multilocularis cyclins 0.006 0.0785 0.0777
Echinococcus multilocularis pyruvate kinase 0.0036 0.0438 0.0426
Echinococcus granulosus G protein coupled receptor 139 0.0067 0.089 0.0883
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.012 0.0662
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0015 0.0044
Echinococcus granulosus cdk5 and abl1 enzyme substrate 1 0.0014 0.012 0.0106
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0067 0.089 0.2076
Onchocerca volvulus Pyruvate kinase homolog 0.0036 0.0438 0.2585
Loa Loa (eye worm) hypothetical protein 0.001 0.006 0.0133
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0093 0.0079
Brugia malayi Pyruvate kinase, muscle isozyme 0.0036 0.0438 0.1661
Trichomonas vaginalis STE family protein kinase 0.0016 0.0142 0.0801
Trichomonas vaginalis cyclin A, putative 0.0115 0.1603 1
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0067 0.089 0.3391
Echinococcus multilocularis neuropeptide receptor 0.0067 0.089 0.0883
Echinococcus granulosus cyclins 0.006 0.0785 0.0777
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0106 0.1466 0.893
Plasmodium vivax hypothetical protein, conserved 0.0108 0.1488 1
Trypanosoma cruzi cdc2-related kinase 1 0.0049 0.0623 0.3875
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0049 0.0623 0.3875
Schistosoma mansoni biogenic amine (5HT) receptor 0.0067 0.089 0.2076
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0067 0.089 0.2076
Plasmodium falciparum cysteine repeat modular protein 1 0.0014 0.0107 0.1329
Loa Loa (eye worm) hypothetical protein 0.002 0.0196 0.0449
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.006 0.0139
Echinococcus multilocularis cyclin A3 4 0.0014 0.012 0.0106
Brugia malayi Nuclear hormone receptor E75 0.0009 0.0044 0.0155
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0008 0.0021 0.0021
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0067 0.089 0.0883
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Loa Loa (eye worm) hypothetical protein 0.0014 0.012 0.0272
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0067 0.089 0.2076
Schistosoma mansoni nuclear receptor nhr-48 0.0009 0.0044 0.0101
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0108 0.1488 1
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0241 0.1484
Onchocerca volvulus 0.0115 0.1603 0.9712
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0015 0.0015
Echinococcus granulosus neuropeptide Y receptor 0.0067 0.089 0.0883
Echinococcus multilocularis cyclin G2 0.0014 0.012 0.0106
Brugia malayi orphan nuclear receptor NR2E1 0.0009 0.0044 0.0155
Onchocerca volvulus Pyruvate kinase homolog 0.0036 0.0438 0.2585
Entamoeba histolytica hypothetical protein 0.0014 0.0107 0.0582
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0214 0.1257
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.012 0.0662
Leishmania major cyclin 0.0115 0.1603 1
Plasmodium falciparum cysteine repeat modular protein 2 0.0014 0.0107 0.1329
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0067 0.089 0.2076
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Toxoplasma gondii hypothetical protein 0.0045 0.0574 0.3842
Onchocerca volvulus 0.0014 0.0107 0.0565
Schistosoma mansoni nuclear receptor 0.0009 0.0044 0.0101
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0119 0.0726
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0008 0.0021 0.0108
Onchocerca volvulus 0.0067 0.089 0.5351
Echinococcus granulosus rhodopsin orphan GPCR 0.0067 0.089 0.0883
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.0179 0.118
Entamoeba histolytica protein kinase, putative 0.0016 0.0142 0.0801
Echinococcus granulosus neuropeptide Y receptor 0.0067 0.089 0.0883
Onchocerca volvulus 0.0108 0.1488 0.9007
Plasmodium vivax cyclin homologue, putative 0.0014 0.012 0.0785
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0008 0.0024 0.0058
Loa Loa (eye worm) hypothetical protein 0.0012 0.0078 0.0174
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.001 0.006 0.0139
Giardia lamblia Hypothetical protein 0.0014 0.012 0.0729
Loa Loa (eye worm) neuropeptide F receptor 0.0067 0.089 0.207
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0067 0.089 0.2076
Loa Loa (eye worm) cytochrome P450 0.0008 0.0021 0.004
Loa Loa (eye worm) hypothetical protein 0.002 0.0196 0.0449
Brugia malayi MH1 domain containing protein 0.0008 0.0026 0.0086
Schistosoma mansoni adenoreceptor 0.0067 0.089 0.2076
Echinococcus multilocularis cyclins 0.006 0.0785 0.0777
Echinococcus granulosus TGF beta signal transducer SmadC 0.0008 0.0026 0.0011
Trichomonas vaginalis cyclin B, putative 0.0014 0.012 0.0662
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0008 0.0021 0.0108
Echinococcus multilocularis cdk5 and abl1 enzyme substrate 1 0.0014 0.012 0.0106
Echinococcus multilocularis G-protein coupled receptor, putative 0.0067 0.089 0.0883
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0455 0.2772
Toxoplasma gondii pyruvate kinase PyK1 0.0036 0.0438 0.2925
Mycobacterium ulcerans acyl-CoA synthetase 0.0007 0.0015 0.0077
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0009 0.0044 0.0155
Entamoeba histolytica p21-activated kinase 0.0037 0.0449 0.2731
Echinococcus granulosus cyclins 0.006 0.0785 0.0777
Loa Loa (eye worm) hypothetical protein 0.0009 0.0044 0.0095
Trypanosoma cruzi cdc2-related kinase 1 0.0049 0.0623 0.3875
Brugia malayi Dopamine receptor 0.0067 0.089 0.3391
Loa Loa (eye worm) hypothetical protein 0.0021 0.0214 0.0493
Brugia malayi ecdysone receptor 0.0009 0.0044 0.0155
Schistosoma mansoni hypothetical protein 0.0067 0.089 0.2076
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.0139 0.0324
Plasmodium falciparum thioredoxin reductase 0.0016 0.0145 0.181
Leishmania major mitotic cyclin, putative 0.0014 0.012 0.0729
Schistosoma mansoni protein kinase 0.0015 0.013 0.0302
Trichomonas vaginalis cyclin B3, putative 0.006 0.0785 0.4851
Entamoeba histolytica hypothetical protein 0.0015 0.013 0.0725
Loa Loa (eye worm) hypothetical protein 0.0108 0.1488 0.3467
Trichomonas vaginalis D-aminoacylase, putative 0.0108 0.1488 0.9274
Loa Loa (eye worm) hypothetical protein 0.0025 0.0271 0.0625
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0145 0.0954
Trypanosoma cruzi mitotic cyclin, putative 0.0014 0.012 0.0729
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0008 0.0024 0.0009
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0108 0.1488 0.1488
Loa Loa (eye worm) beta-lactamase 0.0108 0.1488 0.3467
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0008 0.0024 0.0055
Schistosoma mansoni histamine h1 receptor 0.0067 0.089 0.2076
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0067 0.089 0.0883
Trypanosoma cruzi cdc2-related kinase 3 0.0049 0.0623 0.3875
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0114 0.0422
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0227 0.0528
Loa Loa (eye worm) hypothetical protein 0.0012 0.0086 0.0194
Echinococcus granulosus cyclins 0.0014 0.012 0.0106
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0015 0.0044
Echinococcus granulosus neuropeptide receptor 0.0067 0.089 0.0883
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0007 0.0015 0.0044
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.021 0.1292
Echinococcus multilocularis dro:myosuppressin receptor 0.0067 0.089 0.0883
Mycobacterium leprae Probable lipase LipE 0.0108 0.1488 0.9066
Brugia malayi pyruvate kinase 0.0008 0.002 0.0063
Loa Loa (eye worm) Smad1 0.0008 0.0026 0.0052
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0008 0.0021 0.0116
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0022 0.0227 0.0522
Echinococcus granulosus pyruvate kinase 0.0019 0.018 0.0167
Brugia malayi G protein-coupled receptor F59B2.13 0.0067 0.089 0.3391
Echinococcus granulosus pyruvate kinase 0.0036 0.0438 0.0426
Brugia malayi nuclear receptor NHR-88 0.002 0.0196 0.0736
Plasmodium vivax acetyl-CoA synthetase, putative 0.0007 0.0015 0.0077
Schistosoma mansoni pyruvate kinase 0.0019 0.018 0.0419
Echinococcus multilocularis pyruvate kinase 0.0036 0.0438 0.0426
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0008 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0108 0.1488 0.3467
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.021 0.1392
Schistosoma mansoni nuclear receptor 0.0009 0.0044 0.0101
Loa Loa (eye worm) hypothetical protein 0.0056 0.0726 0.1688
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0185 0.2618 0.2626
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0008 0.0024 0.0009
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0623 0.3831
Loa Loa (eye worm) pyruvate kinase 0.0036 0.0438 0.1014
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Loa Loa (eye worm) cyclin domain-containing protein 0.0014 0.012 0.0272
Brugia malayi Cyclin, N-terminal domain containing protein 0.0115 0.1603 0.6119
Echinococcus granulosus g-protein coupled receptor 0.0067 0.089 0.0883
Echinococcus multilocularis beta LACTamase domain containing family member 0.0108 0.1488 0.1486
Trypanosoma brucei hypothetical protein, conserved 0.0108 0.1488 0.9279
Schistosoma mansoni hypothetical protein 0.0067 0.089 0.2076
Trichomonas vaginalis cyclins, putative 0.0115 0.1603 1
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0008 0.0021 0.0116
Loa Loa (eye worm) hypothetical protein 0.0108 0.1488 0.3467
Echinococcus granulosus nuclear receptor nhr 48 0.0009 0.0044 0.0029
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0007 0.0015 0.0072
Schistosoma mansoni amine GPCR 0.0067 0.089 0.2076
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0008 0.0021 0.0116
Schistosoma mansoni Cyclin fold protein 0.0014 0.012 0.0279
Trypanosoma brucei cyclin 3 0.0014 0.012 0.0729
Brugia malayi GCC2 and GCC3 family protein 0.0014 0.0107 0.0398
Echinococcus granulosus sex peptide receptor 0.0067 0.089 0.0883
Trypanosoma cruzi hypothetical protein, conserved 0.0108 0.1488 0.9279
Trichomonas vaginalis pyruvate kinase, putative 0.0036 0.0438 0.2662
Echinococcus granulosus Nuclear hormone receptor HR96 0.0009 0.0044 0.0029
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0007 0.0015 0.0147
Schistosoma mansoni voltage-gated potassium channel 0.0012 0.0078 0.018
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0067 0.089 0.3391
Loa Loa (eye worm) hypothetical protein 0.0029 0.0333 0.0771
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0108 0.1488 0.1488
Echinococcus granulosus intermediate filament protein 0.0026 0.0292 0.0279
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0118 0.164 1
Loa Loa (eye worm) pyruvate kinase 0.0036 0.0438 0.1014
Echinococcus granulosus neuropeptide receptor A26 0.0067 0.089 0.0883
Echinococcus granulosus biogenic amine 5HT receptor 0.0067 0.089 0.0883
Loa Loa (eye worm) hypothetical protein 0.0014 0.012 0.0272
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0241 0.1422
Loa Loa (eye worm) DR-78 0.0009 0.0044 0.0095
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0214 0.132
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0067 0.089 0.2076
Entamoeba histolytica cyclin C, putative 0.0014 0.012 0.0662
Loa Loa (eye worm) hypothetical protein 0.0018 0.0179 0.0411
Echinococcus multilocularis neuropeptides capa receptor 0.0067 0.089 0.0883
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0292 0.0674
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0271 0.0271
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0106 0.1466 0.1466
Onchocerca volvulus Cyclin L homolog 0.0014 0.012 0.0643
Plasmodium falciparum thioredoxin reductase 0.0047 0.0591 0.7517
Trypanosoma brucei trypanothione reductase 0.0047 0.0591 0.3674
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0012 0.0078 0.0064
Echinococcus granulosus cyclin k 0.0014 0.012 0.0106
Echinococcus multilocularis Cyclin L1 0.0014 0.012 0.0106
Schistosoma mansoni biogenic amine (5HT) receptor 0.0067 0.089 0.2076
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0623 0.1453
Entamoeba histolytica hypothetical protein, conserved 0.0014 0.0107 0.0582
Echinococcus granulosus neuropeptides capa receptor 0.0067 0.089 0.0883
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0008 0.0021 0.0116
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.021 0.0197
Echinococcus multilocularis cyclin 0.0014 0.012 0.0106
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0067 0.089 0.2076
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0214 0.0808
Echinococcus granulosus lamin dm0 0.0026 0.0292 0.0279
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0008 0.0021 0.0021
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0145 0.0885
Trichomonas vaginalis esterase, putative 0.0108 0.1488 0.9274
Mycobacterium tuberculosis Conserved protein 0.0108 0.1488 0.1488
Onchocerca volvulus 0.0067 0.089 0.5351
Echinococcus multilocularis lamin dm0 0.0026 0.0292 0.0279
Schistosoma mansoni smad1 5 8 and 0.0008 0.0026 0.0059
Echinococcus multilocularis pyruvate kinase 0.0019 0.018 0.0167
Echinococcus multilocularis g-protein coupled receptor 0.0067 0.089 0.0883
Loa Loa (eye worm) hypothetical protein 0.0048 0.0611 0.142
Loa Loa (eye worm) hypothetical protein 0.0018 0.0179 0.0411
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.004 0.0494 0.0483
Leishmania major cyclin 9, putative 0.0014 0.012 0.0729
Echinococcus granulosus cyclin dependent kinase 0.0049 0.0623 0.0614
Trypanosoma brucei cyclin dependent kinase-binding protein, putative 0.0014 0.012 0.0729
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0196 0.0736
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0037 0.0449 0.0438
Schistosoma mansoni protein kinase 0.0037 0.0449 0.1046
Echinococcus multilocularis fmrfamide receptor 0.0067 0.089 0.0883
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0271 0.1578
Echinococcus multilocularis rhodopsin orphan GPCR 0.0067 0.089 0.0883
Loa Loa (eye worm) pyruvate kinase-PB 0.0025 0.0277 0.064
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.004 0.0494 0.1145
Entamoeba histolytica hypothetical protein 0.0035 0.0424 0.2579
Echinococcus granulosus cyclin t1 0.0014 0.012 0.0106
Loa Loa (eye worm) hypothetical protein 0.0018 0.0179 0.0411
Trypanosoma cruzi cyclin 9, putative 0.0014 0.012 0.0729
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0196 0.0736
Echinococcus multilocularis neuropeptide Y receptor 0.0067 0.089 0.0883
Brugia malayi WH1 domain containing protein 0.0015 0.013 0.0485
Schistosoma mansoni myosin xvIII 0.0067 0.089 0.2076
Echinococcus granulosus dro:myosuppressin receptor 0.0067 0.089 0.0883
Loa Loa (eye worm) hypothetical protein 0.0119 0.165 0.3846
Echinococcus granulosus importin subunit beta 1 0.0028 0.0318 0.0306
Schistosoma mansoni opsin-like receptor 0.0067 0.089 0.2076
Loa Loa (eye worm) hypothetical protein 0.0025 0.0271 0.0625
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0214 0.132
Echinococcus multilocularis cyclin k 0.0014 0.012 0.0106
Leishmania major importin beta-1 subunit, putative 0.0023 0.0241 0.1484
Echinococcus granulosus lamin 0.0026 0.0292 0.0279
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0145 0.0954
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0165 0.0165
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0196 0.0449
Plasmodium vivax protein kinase Crk2 0.0049 0.0623 0.4176
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.0145 0.0954
Loa Loa (eye worm) hypothetical protein 0.0016 0.0136 0.0311
Schistosoma mansoni hypothetical protein 0.0298 0.4285 1
Giardia lamblia NADH oxidase lateral transfer candidate 0.0016 0.0145 0.0885
Schistosoma mansoni tyrosine kinase 0.0016 0.0139 0.0324
Onchocerca volvulus Cyclin L homolog 0.0014 0.012 0.0643
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0106 0.1466 0.1466
Trichomonas vaginalis cyclins, putative 0.006 0.0785 0.4851
Loa Loa (eye worm) G-protein coupled receptor 0.0067 0.089 0.207
Loa Loa (eye worm) cytochrome P450 family protein 0.0008 0.0021 0.004
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0008 0.0021 0.0116
Echinococcus multilocularis mothers against decapentaplegic 5 0.0008 0.0026 0.0011
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0012 0.0078 0.0064
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0214 0.132
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0082 0.0301
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0591 0.0591
Leishmania major DNA polymerase eta, putative 0.0021 0.0214 0.132
Brugia malayi hypothetical protein 0.0014 0.012 0.0446
Schistosoma mansoni hypothetical protein 0.0016 0.0136 0.0317
Brugia malayi hypothetical protein 0.0067 0.089 0.3391
Brugia malayi tailless protein 0.0009 0.0044 0.0155
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0067 0.089 0.2076
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0009 0.0044 0.0029
Echinococcus granulosus peptide allatostatin:somatostatin 0.0067 0.089 0.0883
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.021 0.1292
Leishmania major pyruvate kinase 0.0036 0.0438 0.2714
Echinococcus multilocularis dna polymerase eta 0.0021 0.0214 0.0201
Giardia lamblia Kinase, STE STE20 0.0037 0.0449 0.2784
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0067 0.089 0.2076
Loa Loa (eye worm) cyclin domain-containing protein 0.0014 0.012 0.0272
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0271 0.1804
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0271 0.1804
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0196 0.0449
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0037 0.0449 0.0438
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0165 0.0165
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0165 0.0165
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0067 0.089 0.2076
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0037 0.0449 0.0438
Entamoeba histolytica hypothetical protein 0.0035 0.0424 0.2579
Trichomonas vaginalis cyclin B, putative 0.0115 0.1603 1
Mycobacterium ulcerans beta-lactamase 0.0108 0.1488 1
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0067 0.089 0.0883
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0214 0.1257
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0067 0.089 0.3391
Brugia malayi Serotonin receptor 0.0067 0.089 0.3391
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0016 0.0142 0.0324
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0007 0.0015 0.0015
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0569 0.1321
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0008 0.0021 0.0116
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0196 0.0182
Brugia malayi RE15519p 0.0067 0.089 0.3391
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0569 0.2163
Echinococcus granulosus thyroid hormone receptor alpha 0.0009 0.0044 0.0029
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0196 0.0182
Brugia malayi hypothetical protein 0.0067 0.089 0.3391
Echinococcus multilocularis PAK box P21 Rho binding 0.0015 0.013 0.0116
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0424 0.0413
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0114 0.0258
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0067 0.089 0.2076
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0007 0.0015 0.0015
Brugia malayi hypothetical protein 0.0067 0.089 0.3391
Schistosoma mansoni amine GPCR 0.0067 0.089 0.2076
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Trichomonas vaginalis cyclin D, putative 0.0014 0.012 0.0662
Entamoeba histolytica cell division protein kinase 2, putative 0.0049 0.0623 0.3831
Trichomonas vaginalis STE family protein kinase 0.0037 0.0449 0.2731
Onchocerca volvulus 0.0057 0.0744 0.4456
Onchocerca volvulus 0.0067 0.089 0.5351
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0008 0.0021 0.0116
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0016 0.0136 0.0123
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0007 0.0015 0.0077
Onchocerca volvulus 0.0067 0.089 0.5351
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0067 0.089 0.0883
Entamoeba histolytica hypothetical protein 0.0015 0.013 0.0725
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0049 0.0623 0.3875
Entamoeba histolytica hypothetical protein 0.0014 0.012 0.0662
Echinococcus granulosus nuclear factor of activated T cells 5 0.008 0.1077 0.1071
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0271 0.1024
Trichomonas vaginalis cyclins, putative 0.0115 0.1603 1
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0067 0.089 0.0883
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0067 0.089 0.3391
Echinococcus multilocularis cyclin dependent kinase 1 0.0049 0.0623 0.0614
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0108 0.1488 0.3467
Schistosoma mansoni Smad4 0.0008 0.0026 0.0059
Echinococcus granulosus death domain containing protein 0.0016 0.0136 0.0123
Echinococcus multilocularis rhodopsin orphan GPCR 0.0067 0.089 0.0883
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0145 0.0885
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0022 0.0227 0.0855
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0015 0.0015
Entamoeba histolytica hypothetical protein 0.0035 0.0424 0.2579
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0007 0.0015 0.0077
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.012 0.0729
Brugia malayi Cyclin, N-terminal domain containing protein 0.0014 0.012 0.0446
Brugia malayi Death domain containing protein 0.0016 0.0136 0.0509
Brugia malayi Serotonin receptor 0.0067 0.089 0.3391
Schistosoma mansoni smad 0.0008 0.0026 0.0059
Echinococcus multilocularis cyclin dependent kinase 5 0.0049 0.0623 0.0614
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.006 0.0217
Trypanosoma brucei pyruvate kinase 1, putative 0.0036 0.0438 0.2714
Trypanosoma brucei pyruvate kinase 1 0.0036 0.0438 0.2714
Schistosoma mansoni cyclin d 0.0014 0.012 0.0279
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0196 0.0455
Loa Loa (eye worm) neuropeptide F receptor 0.0067 0.089 0.207
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Trypanosoma brucei unspecified product 0.0014 0.0119 0.0726
Loa Loa (eye worm) hypothetical protein 0.001 0.006 0.0133
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0591 0.3959
Onchocerca volvulus 0.0067 0.089 0.5351
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0008 0.0021 0.0021
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.021 0.0483
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0145 0.0885
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0196 0.0182
Echinococcus multilocularis hyperpolarization activated cyclic 0.0008 0.0024 0.0009
Brugia malayi Cyclin, N-terminal domain containing protein 0.0014 0.012 0.0446
Trichomonas vaginalis cyclin A, putative 0.0014 0.012 0.0662
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0014 0.012 0.1491
Echinococcus granulosus serine:threonine protein kinase PAK 1 0.0021 0.0215 0.0202
Echinococcus granulosus G1:S specific cyclin D1 0.0014 0.012 0.0106
Trichomonas vaginalis cyclins, putative 0.0115 0.1603 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0196 0.0736
Mycobacterium tuberculosis Probable esterase LipL 0.0108 0.1488 0.1488
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0108 0.1488 0.3471
Loa Loa (eye worm) hypothetical protein 0.0009 0.0044 0.0095
Brugia malayi beta-lactamase 0.0108 0.1488 0.5678
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0196 0.0455
Brugia malayi hypothetical protein 0.001 0.006 0.0217
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0007 0.0015 0.0077
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Echinococcus granulosus PAK box P21 Rho binding 0.0015 0.013 0.0116
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Mycobacterium leprae conserved hypothetical protein 0.0108 0.1488 0.9066
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0067 0.089 0.0883
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Trichomonas vaginalis cyclins, putative 0.0014 0.012 0.0662
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0179 0.1186
Echinococcus multilocularis neuropeptide receptor A26 0.0067 0.089 0.0883
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0318 0.1969
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Echinococcus multilocularis musashi 0.0026 0.0292 0.0279
Trichomonas vaginalis cyclin D, putative 0.006 0.0785 0.4851
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0145 0.5
Echinococcus multilocularis 0.0008 0.0021 0.0006
Plasmodium vivax cyclin dependent kinase binding protein, putative 0.0014 0.012 0.0785
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0016 0.0136 0.0311
Loa Loa (eye worm) cyclin domain-containing protein 0.0014 0.012 0.0272
Mycobacterium tuberculosis Probable reductase 0.0106 0.1466 0.1466
Echinococcus granulosus geminin 0.0167 0.2355 0.2361
Trypanosoma cruzi CYC2-like cyclin, putative 0.0115 0.1603 1
Schistosoma mansoni protein kinase 0.0037 0.0449 0.1046
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0196 0.0736
Brugia malayi hypothetical protein 0.0067 0.089 0.3391
Brugia malayi hypothetical protein 0.0067 0.089 0.3391
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0067 0.089 0.0883
Trypanosoma cruzi cdc2-related kinase 3 0.0049 0.0623 0.3875
Schistosoma mansoni nuclear hormone receptor 0.002 0.0196 0.0455
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Loa Loa (eye worm) cyclin domain-containing protein 0.0014 0.012 0.0272
Echinococcus granulosus tm gpcr rhodopsin 0.0067 0.089 0.0883
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.012 0.0662
Schistosoma mansoni growth hormone secretagogue receptor 0.0067 0.089 0.2076
Mycobacterium ulcerans hypothetical protein 0.0108 0.1488 1
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0067 0.089 0.207
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0196 0.0449
Brugia malayi hypothetical protein 0.0067 0.089 0.3391
Echinococcus granulosus hypothetical protein 0.0067 0.089 0.0883
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0007 0.0015 0.0077
Echinococcus multilocularis cyclins 0.006 0.0785 0.0777
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0196 0.0736
Trypanosoma brucei mitotic cyclin 0.0014 0.012 0.0729
Brugia malayi Cyclin, N-terminal domain containing protein 0.0014 0.012 0.0446
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0214 0.0499
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0067 0.089 0.0883
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0271 0.1804
Echinococcus granulosus tumor protein p63 0.0683 0.9928 1
Plasmodium vivax hypothetical protein, conserved 0.0014 0.0107 0.07
Echinococcus granulosus fmrfamide receptor 0.0067 0.089 0.0883
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0008 0.0024 0.0055
Toxoplasma gondii hypothetical protein 0.0014 0.012 0.0785
Echinococcus granulosus tachykinin peptides receptor 99D 0.0067 0.089 0.0883
Echinococcus granulosus Cyclin L1 0.0014 0.012 0.0106
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0136 0.0509
Echinococcus granulosus cyclin G2 0.0014 0.012 0.0106
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0015 0.0015
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0008 0.0021 0.0021
Trypanosoma brucei mitotic cyclin 6 0.0115 0.1603 1
Echinococcus granulosus pyruvate kinase 0.0036 0.0438 0.0426
Brugia malayi steroid hormone receptor 0.002 0.0196 0.0736
Entamoeba histolytica hypothetical protein 0.0023 0.0241 0.1422
Schistosoma mansoni ran 0.0021 0.021 0.0489
Echinococcus granulosus Smad4 0.0008 0.0026 0.0011
Brugia malayi Cytochrome P450 family protein 0.0008 0.0021 0.0066
Brugia malayi Tachykinin-like peptides receptor 99D 0.0067 0.089 0.3391
Schistosoma mansoni biogenic amine receptor 0.0067 0.089 0.2076
Onchocerca volvulus Neuropeptide F receptor homolog 0.0067 0.089 0.5351
Onchocerca volvulus Protein CNPPD1 homolog 0.0014 0.012 0.0643
Echinococcus granulosus biogenic amine 5HT receptor 0.0067 0.089 0.0883
Schistosoma mansoni hypothetical protein 0.0015 0.013 0.0302
Loa Loa (eye worm) hypothetical protein 0.0036 0.0437 0.1012
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Brugia malayi Nuclear hormone receptor E75 0.0009 0.0044 0.0155
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0007 0.0015 0.0077
Onchocerca volvulus 0.0067 0.089 0.5351
Brugia malayi GCC2 and GCC3 family protein 0.0014 0.0107 0.0398
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0591 0.0581
Plasmodium vivax importin-beta 2, putative 0.0028 0.0318 0.2122
Schistosoma mansoni cyclin l 0.0014 0.012 0.0279
Loa Loa (eye worm) hypothetical protein 0.0009 0.0044 0.0095
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0067 0.089 0.2076
Schistosoma mansoni hypothetical protein 0.0014 0.0107 0.0249
Loa Loa (eye worm) pyruvate kinase 0.0036 0.0438 0.1014
Brugia malayi Cyclin, N-terminal domain containing protein 0.0115 0.1603 0.6119
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0196 0.0182
Brugia malayi GCC2 and GCC3 family protein 0.0014 0.0107 0.0398
Brugia malayi Protein kinase domain 0.0037 0.0449 0.1703
Echinococcus granulosus Ankyrin 0.0016 0.0138 0.0125
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0007 0.0015 0.0072
Echinococcus granulosus allatostatin A receptor 0.0067 0.089 0.0883
Mycobacterium ulcerans acyl-CoA synthetase 0.0007 0.0015 0.0077
Brugia malayi MH2 domain containing protein 0.0008 0.0026 0.0086
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Brugia malayi RNA, U transporter 1 0.0079 0.1074 0.4096
Entamoeba histolytica protein kinase, putative 0.0037 0.0449 0.2731
Entamoeba histolytica cyclin, domain containing protein 0.0014 0.012 0.0662
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0007 0.0015 0.0072
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0318 0.0306
Brugia malayi putative neuropeptide receptor NPR1 0.0067 0.089 0.3391
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0008 0.0021 0.0116
Trichomonas vaginalis cyclin B3, putative 0.0014 0.012 0.0662
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0022 0.0227 0.1398
Schistosoma mansoni opsin-like receptor 0.0067 0.089 0.2076
Schistosoma mansoni cyclin B3 0.0185 0.2618 0.6108
Loa Loa (eye worm) hypothetical protein 0.0057 0.0744 0.1729
Schistosoma mansoni ran 0.0021 0.021 0.0489
Loa Loa (eye worm) cytochrome P450 family protein 0.0008 0.0021 0.004
Echinococcus granulosus rhodopsin orphan GPCR 0.0067 0.089 0.0883
Echinococcus granulosus somatostatin receptor 0.0067 0.089 0.0883
Echinococcus multilocularis rhodopsin orphan GPCR 0.0067 0.089 0.0883
Giardia lamblia DINP protein human, muc B family 0.0021 0.0214 0.132
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0145 0.0337
Echinococcus multilocularis G protein coupled receptor 139 0.0067 0.089 0.0883
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0007 0.0015 0.0077
Brugia malayi Cyclin, N-terminal domain containing protein 0.0014 0.012 0.0446
Loa Loa (eye worm) hypothetical protein 0.0026 0.0292 0.0674
Echinococcus multilocularis cyclin dependent kinase 0.0049 0.0623 0.0614
Trypanosoma brucei DNA polymerase eta, putative 0.0021 0.0214 0.132
Schistosoma mansoni lamin 0.0026 0.0292 0.068
Trypanosoma brucei cdc2-related kinase 1 0.0049 0.0623 0.3875
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0214 0.132
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0115 0.1603 1
Trichomonas vaginalis D-aminoacylase, putative 0.0108 0.1488 0.9274
Loa Loa (eye worm) hypothetical protein 0.0067 0.089 0.207
Onchocerca volvulus 0.0067 0.089 0.5351
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0227 0.0528
Brugia malayi beta-lactamase family protein 0.0108 0.1488 0.5678
Schistosoma mansoni hypothetical protein 0.0008 0.0021 0.0047
Trypanosoma cruzi pyruvate kinase 2, putative 0.0036 0.0438 0.2714
Echinococcus granulosus FTZ F1 alpha 0.002 0.0196 0.0182
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0009 0.0044 0.0095
Mycobacterium leprae Conserved hypothetical protein 0.0008 0.0021 0.0035

Activities

Activity type Activity value Assay description Source Reference
Activity (binding) = 3.9 % Evaluated in vitro for inhibition of mitochondrial aldehyde dehydrogenase (AIDH) activity in intact rat liver mitochondria (0.2 mM) ChEMBL. 6541256
Activity (binding) = 3.9 % Evaluated in vitro for inhibition of mitochondrial aldehyde dehydrogenase (AIDH) activity in intact rat liver mitochondria (0.2 mM) ChEMBL. 6541256

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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