Detailed information for compound 353968

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 381.347 | Formula: C20H29BrO2
  • H donors: 2 H acceptors: 2 LogP: 3.98 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: Br/C=C/[C@]12CC[C@@H](CC1=CCC1C2CC[C@]2(C1CC[C@@H]2O)C)O
  • InChi: 1S/C20H29BrO2/c1-19-8-7-17-15(16(19)4-5-18(19)23)3-2-13-12-14(22)6-9-20(13,17)10-11-21/h2,10-11,14-18,22-23H,3-9,12H2,1H3/b11-10+/t14-,15?,16?,17?,18-,19-,20+/m0/s1
  • InChiKey: REWRFXZVVOUSFK-ALBGZISYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens estrogen receptor 2 (ER beta) Starlite/ChEMBL References
Homo sapiens androgen receptor Starlite/ChEMBL References
Homo sapiens estrogen receptor 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) hypothetical protein estrogen receptor 2 (ER beta) 495 aa 418 aa 25.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0045 0.0202 0.0949
Echinococcus multilocularis expressed conserved protein 0.0099 0.0573 0.0573
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0154 0.0361
Echinococcus multilocularis protein dispatched 1 0.0051 0.0245 0.0245
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0047 0.0211 0.0929
Echinococcus granulosus FTZ F1 alpha 0.0047 0.0211 0.0211
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0022 0.004 0.004
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0016 0.0000020069 0.0000020069
Trypanosoma cruzi succinate dehydrogenase, putative 0.0033 0.0119 0.056
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0615 0.417 1
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0024 0.0055 0.0055
Echinococcus multilocularis nuclear receptor nhr 48 0.0022 0.004 0.004
Trichomonas vaginalis bromodomain-containing protein, putative 0.005 0.0234 0.0553
Brugia malayi steroid hormone receptor 0.0047 0.0211 0.0929
Trypanosoma brucei ISWI complex protein 0.0016 0 0.0001
Brugia malayi hypothetical protein 0.002 0.0029 0.0128
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0027 0.0078 0.0078
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0204 0.1311 0.1311
Echinococcus multilocularis phosphoserine phosphatase 0.0029 0.0088 0.0088
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0024 0.0055 0.0258
Schistosoma mansoni lipoxygenase 0.0057 0.0286 0.0286
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0155 0.0728
Onchocerca volvulus 0.006 0.0308 0.1692
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0024 0.0055 0.0615
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0037 0.0143 0.0335
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0053 0.0255 0.0255
Brugia malayi potential phospholipid-transporting ATPase IIB, putative 0.0046 0.0204 0.0898
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0022 0.004 0.0175
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0053 0.0255 0.1119
Schistosoma mansoni lipoxygenase 0.002 0.0029 0.0029
Echinococcus granulosus nervana 2 0.0217 0.1402 0.1402
Loa Loa (eye worm) hypothetical protein 0.0032 0.0111 0.0489
Giardia lamblia NADH oxidase lateral transfer candidate 0.0024 0.0055 0.0124
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0046 0.0204 0.0482
Plasmodium falciparum histone acetyltransferase GCN5 0.0042 0.0177 0.1979
Echinococcus multilocularis dna polymerase kappa 0.0043 0.0183 0.0183
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0047 0.0211 0.0929
Echinococcus multilocularis nervana 2 0.0217 0.1402 0.1402
Schistosoma mansoni cation-transporting atpase worm 0.0046 0.0204 0.0204
Schistosoma mansoni caspase-7 (C14 family) 0.0121 0.0732 0.0732
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0033 0.0118 0.0556
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0111 0.0523
Schistosoma mansoni hypothetical protein 0.0043 0.0189 0.0189
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0098 0.057 0.2507
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0029 0.0088 0.0981
Schistosoma mansoni cpg binding protein 0.0066 0.0346 0.0346
Echinococcus multilocularis caspase 8 0.0046 0.0206 0.0206
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0154 0.0154
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0183 0.0862
Brugia malayi Glycosyl hydrolases family 31 protein 0.0174 0.1097 0.482
Loa Loa (eye worm) hypothetical protein 0.0051 0.0244 0.1073
Schistosoma mansoni thyroid hormone receptor 0.0047 0.0211 0.0211
Echinococcus multilocularis bloom syndrome protein 0.0044 0.0192 0.0192
Mycobacterium tuberculosis Conserved hypothetical protein 0.0048 0.0218 0.021
Plasmodium vivax copper-transporting ATPase, putative 0.0046 0.0204 0.2288
Giardia lamblia DINP protein human, muc B family 0.0022 0.0039 0.0085
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0046 0.0204 0.0898
Wolbachia endosymbiont of Brugia malayi succinate dehydrogenase iron-sulfur subunit 0.0052 0.0249 1
Leishmania major calcium motive p-type ATPase, putative 0.0116 0.0692 0.3251
Brugia malayi Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0116 0.0692 0.3043
Plasmodium falciparum cation transporting ATPase, putative 0.0017 0.0003 0.0037
Trypanosoma brucei N-acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase 0.0048 0.0218 0.1026
Trypanosoma cruzi metacaspase, putative 0.0046 0.0206 0.0969
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0047 0.0211 0.0211
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0039 0.0183
Schistosoma mansoni hypothetical protein 0.0313 0.2068 0.2068
Mycobacterium ulcerans DNA polymerase IV 0.0043 0.0183 0.0168
Plasmodium vivax glutathione reductase, putative 0.0053 0.0254 0.2842
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0175
Leishmania major cation-transporting ATPase, putative 0.0017 0.0003 0.0016
Treponema pallidum NADH oxidase 0.0024 0.0055 0.0069
Brugia malayi Bromodomain containing protein 0.0089 0.0507 0.2228
Leishmania major hypothetical protein, conserved 0.0029 0.0087 0.0409
Echinococcus granulosus Niemann Pick C1 protein 0.0105 0.0618 0.0618
Mycobacterium tuberculosis Probable oxidoreductase 0.012 0.0721 0.0734
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0046 0.0206 0.0487
Mycobacterium tuberculosis Probable dehydrogenase 0.0109 0.0644 0.0654
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0155 0.0364
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0047 0.0211 0.0929
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0022 0.004 0.0203
Trypanosoma brucei metacaspase MCA2 0.0046 0.0206 0.0969
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0144 0.0893 0.4195
Leishmania major P-type ATPase, putative 0.0116 0.0692 0.3251
Schistosoma mansoni patched 1 0.0045 0.02 0.02
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0059 0.0301 0.1415
Toxoplasma gondii P-type ATPase PMA1 0.0092 0.0527 0.5902
Echinococcus multilocularis phosphoserine phosphatase 0.0029 0.0088 0.0088
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0031 0.0099 0.0099
Echinococcus multilocularis lysine specific demethylase 5A 0.0061 0.0312 0.0312
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0144 0.0893 1
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0144 0.0893 0.4195
Echinococcus multilocularis neutral alpha glucosidase AB 0.0039 0.0155 0.0155
Loa Loa (eye worm) hypothetical protein 0.0025 0.0058 0.0256
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0099 0.1111
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0029 0.0326
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.0144 0.0893 0.0883
Treponema pallidum hypothetical protein 0.0029 0.0088 0.0148
Echinococcus granulosus nervana 2 0.0217 0.1402 0.1402
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0024 0.0055 0.0904
Echinococcus multilocularis cation transporting atpase worm 0.0046 0.0204 0.0204
Schistosoma mansoni cation-transporting atpase 13a1 (G-box binding protein) 0.0046 0.0204 0.0204
Onchocerca volvulus 0.002 0.0029 0.0144
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0047 0.0211 0.0929
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0155 0.0364
Loa Loa (eye worm) RecQ helicase 0.0044 0.0192 0.0845
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0615 0.417 1
Entamoeba histolytica plasma membrane calcium-transporting ATPase 1, putative 0.0081 0.0454 0.1081
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0116 0.0692 0.3251
Echinococcus granulosus caspase 8 0.0046 0.0206 0.0206
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0013 0.0013
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0047 0.0211 0.1157
Trypanosoma brucei DNA polymerase IV, putative 0.0036 0.0136 0.0638
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0155 0.0364
Echinococcus granulosus fetal alzheimer antigen falz 0.0027 0.0078 0.0078
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0053 0.0255 0.1119
Schistosoma mansoni succinate dehydrogenase 0.0022 0.004 0.004
Echinococcus granulosus nuclear receptor nhr 48 0.0022 0.004 0.004
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.035 0.1538
Leishmania major DNA polymerase kappa, putative 0.0022 0.0039 0.0183
Mycobacterium ulcerans succinate dehydrogenase flavoprotein subunit 0.0022 0.004 0.0024
Loa Loa (eye worm) mbt repeat family protein 0.0051 0.0241 0.1059
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0175
Echinococcus granulosus histone acetyltransferase KAT2B 0.005 0.0234 0.0234
Echinococcus multilocularis CREB binding protein 0.0017 0.0007 0.0007
Schistosoma mansoni hypothetical protein 0.0043 0.0189 0.0189
Trypanosoma cruzi phospholipid-translocating ATPase, putative 0.0017 0.0003 0.0016
Mycobacterium tuberculosis Probable cation transporter P-type ATPase D CtpD 0.0046 0.0204 0.0196
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0037 0.0143 0.0335
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0077 0.0427 0.2003
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0029 0.0029
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0047 0.0211 0.0929
Brugia malayi Thioredoxin reductase 0.0053 0.0254 0.1116
Trypanosoma brucei cation-transporting ATPase, putative 0.0046 0.0204 0.096
Plasmodium falciparum cation transporting P-ATPase 0.0017 0.0003 0.0037
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0039 0.0155 0.0682
Onchocerca volvulus 0.0275 0.1801 1
Toxoplasma gondii hypothetical protein 0.0052 0.0248 0.2781
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0099 0.0436
Loa Loa (eye worm) calcium ATPase 0.0017 0.0003 0.0015
Brugia malayi Sodium/potassium-transporting ATPase alpha-3 chain, putative 0.0063 0.0326 0.1434
Echinococcus multilocularis protein quaking 0.0029 0.0089 0.0089
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0063 0.0326 0.1529
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0258 0.0612
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0034 0.0126 0.1413
Entamoeba histolytica cation-transporting P-typeATPase, putative 0.0046 0.0204 0.0482
Schistosoma mansoni calcium-transporting atpase 2 (atpase 2) 0.0116 0.0692 0.0692
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0206 0.0487
Loa Loa (eye worm) bromodomain containing protein 0.0024 0.0057 0.0251
Mycobacterium ulcerans cation-transporter p-type ATPase B CtpB 0.0046 0.0204 0.0189
Toxoplasma gondii aldehyde dehydrogenase 0.0063 0.0326 0.3644
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0053 0.0255 0.0255
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0047 0.0211 0.0211
Trypanosoma cruzi calcium-transporting ATPase, putative 0.0069 0.0369 0.1735
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0047 0.0211 0.0211
Schistosoma mansoni hypothetical protein 0.0043 0.0189 0.0189
Echinococcus granulosus mitogen activated protein kinase 3 0.0053 0.0258 0.0258
Onchocerca volvulus 0.002 0.0029 0.0144
Echinococcus granulosus RUN 0.002 0.0029 0.0029
Brugia malayi hypothetical protein 0.0025 0.0058 0.0256
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0126 0.0114
Echinococcus granulosus sterol regulatory element binding protein 0.0045 0.02 0.02
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0154 0.0721
Trypanosoma brucei protein kinase, putative 0.0053 0.0258 0.1213
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0047 0.0211 0.0211
Brugia malayi nuclear hormone receptor 0.0047 0.0211 0.0929
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0036 0.0136 0.1522
Plasmodium falciparum guanylyl cyclase 0.0017 0.0003 0.0037
Giardia lamblia Copper-transporting P-type ATPase 0.0046 0.0204 0.0482
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0109 0.0644 0.0654
Brugia malayi F/Y-rich N-terminus family protein 0.0022 0.0038 0.0168
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0175
Onchocerca volvulus 0.0036 0.0136 0.0738
Trypanosoma brucei DNA polymerase IV, putative 0.0043 0.0183 0.0862
Giardia lamblia Potassium-transporting ATPase alpha chain 1 0.0116 0.0692 0.1653
Trypanosoma brucei phospholipid-transporting ATPase 1-like protein, putative 0.0017 0.0003 0.0016
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0217 0.1402 0.1402
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0154 0.0721
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0058 0.029 0.029
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0047 0.0211 0.0211
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0036 0.0136 0.0136
Brugia malayi mbt repeat family protein 0.0051 0.0241 0.1059
Schistosoma mansoni ATPase 0.0144 0.0893 0.0893
Echinococcus granulosus sodium:potassium transporting ATPase subunit 0.0217 0.1402 0.1402
Echinococcus granulosus eukaryotic translation initiation factor 4E 0.0037 0.0143 0.0143
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0024 0.0055 0.1285
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0037 0.0143 0.0335
Leishmania major NADH dehydrogenase, putative 0.0034 0.0126 0.0593
Schistosoma mansoni hypothetical protein 0.0022 0.004 0.004
Trypanosoma brucei metacaspase 5, putative 0.0046 0.0206 0.0969
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0046 0.0204 0.2288
Schistosoma mansoni nuclear hormone receptor 0.0047 0.0211 0.0211
Brugia malayi nuclear hormone receptor family member odr-7 0.0022 0.004 0.0175
Onchocerca volvulus 0.0047 0.0211 0.1157
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0026 0.0294
Trypanosoma cruzi trypanothione reductase, putative 0.0024 0.0055 0.0258
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0047 0.0211 0.0211
Echinococcus multilocularis thioredoxin glutathione reductase 0.0053 0.0258 0.0258
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0144 0.0893 0.0883
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.03 0.1979 0.2046
Echinococcus granulosus caspase 3 0.0075 0.0412 0.0412
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0258 0.0258
Echinococcus multilocularis SAM and MBT domain containing protein 0.0051 0.0241 0.0241
Mycobacterium tuberculosis Probable metal cation transporter ATPase P-type CtpE 0.0046 0.0204 0.0196
Echinococcus granulosus apoptotic protease activating factor 1 0.0043 0.0184 0.0184
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0111 0.0663 0.0663
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.0183 0.0862
Echinococcus multilocularis succinate dehydrogenase (ubiquinone) iron sulfur 0.0033 0.0119 0.0119
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase CtpV 0.0046 0.0204 0.0196
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0154 0.0361
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0615 0.417 1
Brugia malayi nuclear receptor RXR 0.0022 0.004 0.0175
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0116 0.0692 0.0692
Loa Loa (eye worm) translation initiation factor 4E 0.0037 0.0143 0.0628
Brugia malayi Pre-SET motif family protein 0.0242 0.157 0.6902
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0116 0.0692 0.1653
Leishmania major mitochondrial DNA polymerase beta 0.0322 0.213 1
Leishmania major succinate dehydrogenase, putative 0.0033 0.0119 0.056
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0047 0.0211 0.0929
Schistosoma mansoni nuclear receptor 0.0022 0.004 0.004
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.0126 0.0086
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0615 0.417 1
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0059 0.0301 0.0301
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0053 0.0258 0.2891
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0024 0.0055 0.0258
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0024 0.0055 0.0258
Loa Loa (eye worm) DR-78 0.0022 0.004 0.0175
Plasmodium vivax thioredoxin reductase, putative 0.0053 0.0254 0.2842
Schistosoma mansoni phospholipid-transporting atpase 1 (aminophospholipid flippase 1) 0.0017 0.0003 0.0003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0047 0.0211 0.0929
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0144 0.0893 0.0893
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0217 0.1402 0.1402
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0155 0.0364
Echinococcus granulosus histone lysine methyltransferase setb 0.0054 0.0263 0.0263
Echinococcus multilocularis cation transporting ATPase 13A1 0.0046 0.0204 0.0204
Brugia malayi photoreceptor-specific nuclear receptor 0.0047 0.0211 0.0929
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0077 0.0427 0.2003
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0183 0.0862
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0053 0.0254 0.0247
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0144 0.0893 0.0893
Echinococcus multilocularis succinate dehydrogenase (ubiquinone) 0.0022 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0175
Loa Loa (eye worm) hypothetical protein 0.0046 0.0204 0.0898
Mycobacterium leprae Mycothiol conjugate amidase Mca (Mycothiol S-conjugate amidase) 0.1442 0.9941 1
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0121 0.0732 0.0732
Brugia malayi jmjC domain containing protein 0.0061 0.0312 0.137
Mycobacterium ulcerans cation transporter p-type ATPase D CtpD 0.0046 0.0204 0.0189
Brugia malayi Membrane calcium atpase protein 3 0.0116 0.0692 0.3043
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0116 0.0692 0.0692
Giardia lamblia Kinase, STE STE20 0.0077 0.0427 0.1016
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0006 0.003
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.004 0.004
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0047 0.0211 0.0211
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0047 0.0211 0.0211
Schistosoma mansoni ap endonuclease 0.002 0.0026 0.0026
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.013 0.0792 0.0809
Echinococcus multilocularis caspase 0.0121 0.0732 0.0732
Toxoplasma gondii P-type ATPase4, putative 0.0144 0.0893 1
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0051 0.0241 0.1321
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0615 0.417 1
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0144 0.0893 0.4195
Plasmodium falciparum calcium-transporting ATPase 0.0116 0.0692 0.775
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0154 0.0361
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0152 0.0948 0.4452
Schistosoma mansoni hypothetical protein 0.0029 0.0089 0.0089
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0018 0.0013 0.0013
Mycobacterium tuberculosis Cation transporter P-type ATPase a CtpA 0.0046 0.0204 0.0196
Chlamydia trachomatis succinate dehydrogenase iron sulfur subunit 0.0029 0.0087 0.2867
Brugia malayi Uncharacterized LmbE-like protein, COG2120 containing protein 0.0048 0.0218 0.096
Echinococcus multilocularis Ca2+ transporting ATPase plasma membrane 0.0116 0.0692 0.0692
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0045 0.02 0.0881
Echinococcus granulosus Nuclear hormone receptor HR96 0.0022 0.004 0.004
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.0183 0.0862
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0026 0.0026
Schistosoma mansoni DNA helicase recq5 0.0031 0.0099 0.0099
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0144 0.0893 1
Trypanosoma cruzi Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 0.0022 0.004 0.0188
Loa Loa (eye worm) calcium ATPase 0.0081 0.0454 0.1994
Echinococcus granulosus phospholipid transporting ATPase IA 0.0017 0.0003 0.0003
Echinococcus granulosus histone acetyltransferase KAT2B 0.015 0.0933 0.0933
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0046 0.0204 0.096
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0058 0.029 0.1274
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0175
Echinococcus multilocularis protein patched 0.0045 0.02 0.02
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0144 0.0893 0.2136
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0144 0.0893 0.2136
Brugia malayi Nuclear hormone receptor E75 0.0022 0.004 0.0175
Toxoplasma gondii N-acetylglucosaminylphosphatidylinositol deacetylase 0.0048 0.0218 0.2445
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0054 0.0263 0.0263
Trichomonas vaginalis glutathione reductase, putative 0.0024 0.0055 0.0124
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0121 0.0732 0.0732
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0029 0.0029
Toxoplasma gondii cation-transporting atpase family protein 0.0029 0.0088 0.0981
Echinococcus multilocularis cation transporting ATPase 13A3 0.0046 0.0204 0.0204
Trypanosoma cruzi ISWI complex protein 0.0016 0 0.0001
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0016 0.0000020069 0.0000020069
Loa Loa (eye worm) hypothetical protein 0.0144 0.0893 0.3927
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0144 0.0893 0.0893
Mycobacterium tuberculosis Probable succinate dehydrogenase (flavoprotein subunit) SdhA (succinic dehydrogenase) (fumarate reductase) (fumarate dehydrogena 0.0022 0.004 0.0024
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0144 0.0893 0.2136
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.004 0.004
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0024 0.0055 0.0242
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0024 0.0055 0.0615
Brugia malayi Nuclear hormone receptor-like 1 0.0025 0.0058 0.0256
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.0183 0.0862
Loa Loa (eye worm) hypothetical protein 0.0069 0.0369 0.1624
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0155 0.0364
Echinococcus granulosus cation transporting ATPase 13A1 0.0046 0.0204 0.0204
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0037 0.0143 0.0335
Plasmodium vivax Adenylate and Guanylate cyclase catalytic domain containing protein 0.0017 0.0003 0.0037
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0615 0.417 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0058 0.0256
Onchocerca volvulus Cell death protein 3 homolog 0.0089 0.0504 0.2786
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0045 0.0202 0.0949
Toxoplasma gondii heavy metal translocating P-type ATPase subfamily protein 0.0046 0.0204 0.2288
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0077 0.0427 0.1875
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0136 0.0136
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0024 0.0055 0.0039
Trypanosoma cruzi copper-transporting ATPase, putative 0.0029 0.0088 0.0412
Echinococcus multilocularis phospholipid transporting ATPase IA 0.0017 0.0003 0.0003
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.013 0.0792 0.076
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0053 0.0255 0.0255
Plasmodium vivax histone acetyltransferase GCN5, putative 0.005 0.0234 0.2615
Echinococcus granulosus mixed lineage leukemia protein mll 0.0016 0.0000020069 0.0000020069
Echinococcus multilocularis nervana 2 0.0217 0.1402 0.1402
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0326 0.0326
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0175
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.012 0.0721 0.0688
Brugia malayi hypothetical protein 0.0025 0.0058 0.0256
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0047 0.0211 0.0211
Echinococcus multilocularis phospholipid transporting atpase ih phospholipid transporting atpase if 0.0017 0.0003 0.0003
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0022 0.004 0.004
Schistosoma mansoni hypothetical protein 0.002 0.0029 0.0029
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0046 0.0204 0.0482
Plasmodium vivax iron-sulfur subunit of succinate dehydrogenase, putative 0.0052 0.0249 0.2791
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0029 0.0088 0.0412
Trypanosoma brucei trypanothione reductase 0.0053 0.0254 0.1192
Trypanosoma cruzi P-type H+-ATPase, putative 0.0063 0.0326 0.1532
Loa Loa (eye worm) hypothetical protein 0.0047 0.0211 0.0929
Schistosoma mansoni transmemberane protein 0.0217 0.1402 0.1402
Trichomonas vaginalis ATPase, class I, type 8B, putative 0.0046 0.0204 0.0482
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0144 0.0893 0.2136
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0116 0.0692 0.3251
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0183 0.0862
Echinococcus multilocularis neuropeptide receptor A26 0.0493 0.3321 0.3321
Echinococcus granulosus succinate dehydrogenase ubiquinone iron sulfur 0.0052 0.0249 0.0249
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0053 0.0255 0.0255
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0029 0.0029
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0047 0.0211 0.0211
Loa Loa (eye worm) hypothetical protein 0.0047 0.0211 0.0929
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0022 0.0039 0.0023
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0047 0.0211 0.0211
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.0183 0.0862
Schistosoma mansoni rab6-interacting 0.002 0.0029 0.0029
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0024 0.0055 0.0039
Leishmania major eukaryotic translation initiation factor-like 0.0037 0.0143 0.067
Schistosoma mansoni succinate dehydrogenase iron-sulfur protein 0.0052 0.0249 0.0249
Loa Loa (eye worm) hypothetical protein 0.0025 0.0058 0.0256
Echinococcus multilocularis apoptotic protease activating factor 1 0.0043 0.0184 0.0184
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0054 0.0263 0.0263
Trichomonas vaginalis cation-transporting ATPase, putative 0.0144 0.0893 0.2136
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0022 0.0039 0.0183
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0159 0.0993 0.0993
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0615 0.417 1
Schistosoma mansoni nuclear receptor 0.0022 0.004 0.004
Echinococcus multilocularis mitogen activated protein kinase 3 0.0053 0.0258 0.0258
Echinococcus multilocularis phosphoserine phosphatase 0.0029 0.0088 0.0088
Echinococcus granulosus succinate dehydrogenase ubiquinone 0.0022 0.004 0.004
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0026 0.0116
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0022 0.004 0.0175
Mycobacterium ulcerans metal cation transporter p-type ATPase, CtpV 0.0046 0.0204 0.0189
Trypanosoma brucei glucosidase, putative 0.0039 0.0155 0.0728
Trichomonas vaginalis DNA helicase recq, putative 0.0044 0.0192 0.0454
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0111 0.0523
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0159 0.0993 0.0993
Schistosoma mansoni retinoic acid receptor RXR 0.0047 0.0211 0.0211
Echinococcus granulosus neuropeptide receptor A26 0.0493 0.3321 0.3321
Echinococcus multilocularis zinc finger protein 0.003 0.0095 0.0095
Echinococcus multilocularis polycomb protein SCMH1 0.0051 0.0241 0.0241
Schistosoma mansoni bromodomain containing protein 0.0076 0.042 0.042
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0046 0.0206 0.0487
Schistosoma mansoni caspase-7 (C14 family) 0.0089 0.0504 0.0504
Loa Loa (eye worm) hypothetical protein 0.002 0.0029 0.0128
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0174 0.1097 0.482
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.005 0.0234 0.2615
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0063 0.0326 0.0326
Echinococcus multilocularis CREB binding protein 0.0017 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0018 0.0015 0.0065
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0022 0.004 0.004
Loa Loa (eye worm) thioredoxin reductase 0.0053 0.0254 0.1116
Loa Loa (eye worm) steroid hormone receptor 0.0047 0.0211 0.0929
Schistosoma mansoni protein kinase 0.0077 0.0427 0.0427
Giardia lamblia Glucosamine-6-phosphate isomerase, putative 0.0048 0.0218 0.0516
Toxoplasma gondii histone lysine methyltransferase SET1 0.0124 0.075 0.8392
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0175
Loa Loa (eye worm) hypothetical protein 0.0047 0.0211 0.0929
Leishmania major eukaryotic translation initiation factor-like protein 0.0037 0.0143 0.067
Toxoplasma gondii succinate dehydrogenase [ubiquinone] iron-sulfur protein 0.0052 0.0249 0.2791
Echinococcus multilocularis phosphoserine phosphatase 0.0029 0.0088 0.0088
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0129 0.0788 0.0788
Schistosoma mansoni alpha glucosidase 0.0039 0.0155 0.0155
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0024 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0055 0.0271 0.1191
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0047 0.0211 0.0929
Trypanosoma brucei P-type H+-ATPase, putative 0.0092 0.0527 0.2476
Brugia malayi E1-E2 ATPase family protein 0.0046 0.0204 0.0898
Schistosoma mansoni sex comb on midleg homolog 0.0051 0.0241 0.0241
Trypanosoma brucei unspecified product 0.0036 0.0136 0.0638
Leishmania major eukaryotic translation initiation factor eIF-4E, putative 0.0037 0.0143 0.067
Loa Loa (eye worm) hypothetical protein 0.0051 0.0241 0.1059
Brugia malayi Na,K-ATPase alpha subunit 0.0144 0.0893 0.3927
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0046 0.0206 0.0206
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0063 0.0326 0.1532
Schistosoma mansoni succinate dehydrogenase iron-sulfur protein 0.0029 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0063 0.0326 0.1434
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0326 0.0326
Loa Loa (eye worm) inositol-1 0.0038 0.0154 0.0675
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0046 0.0204 0.0482
Loa Loa (eye worm) hypothetical protein 0.0041 0.0172 0.0754
Echinococcus multilocularis ecdysone induced protein 78C 0.0047 0.0211 0.0211
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0055 0.0273 0.1202
Onchocerca volvulus Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial homolog 0.0022 0.004 0.0205
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0183 0.0862
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0615 0.417 1
Trypanosoma cruzi phospholipid-transporting ATPase 1-like protein, putative 0.0017 0.0003 0.0016
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0154 0.0721
Trichomonas vaginalis maltase-glucoamylase, putative 0.0039 0.0155 0.0364
Schistosoma mansoni phospholipid-transporting atpase 0.0017 0.0003 0.0003
Leishmania major N-acetyl-D-acetylglucosaminylphosphatidylinositol deacetylase 0.0048 0.0218 0.1026
Toxoplasma gondii cation-transporting ATPase, putative 0.0017 0.0003 0.0037
Plasmodium falciparum E1-E2 ATPase, putative 0.0017 0.0003 0.0037
Echinococcus granulosus mitogen activated protein kinase 0.0053 0.0258 0.0258
Brugia malayi succinate dehydrogenase [ubiquinone] iron-sulfur protein, mitochondrial 0.0052 0.0249 0.1096
Mycobacterium ulcerans cation transporter p-type ATPase a CtpA 0.0046 0.0204 0.0189
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0326 0.0311
Loa Loa (eye worm) tumor suppressor 0.0343 0.2275 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0022 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0075 0.0412 0.181
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0105 0.0618 0.1475
Schistosoma mansoni alpha-glucosidase 0.0149 0.0928 0.0928
Entamoeba histolytica glucosamine-6-phosphate isomerase, putative 0.0048 0.0218 0.0516
Loa Loa (eye worm) MBCTL1 0.0058 0.029 0.1274
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0046 0.0206 0.0487
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0046 0.0206 0.0487
Trichomonas vaginalis STE family protein kinase 0.0077 0.0427 0.1016
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0144 0.0893 0.3927
Brugia malayi Doublecortin family protein 0.002 0.0029 0.0128
Brugia malayi nuclear receptor NHR-67 0.0022 0.004 0.0175
Toxoplasma gondii P-type ATPase of unknown pump specificity (type V) protein 0.0017 0.0003 0.0037
Mycobacterium leprae Probable metal cation-transporting P-type ATPase C CtpC 0.0046 0.0204 0.0166
Entamoeba histolytica acetyltransferase, GNAT family 0.0042 0.0177 0.0416
Leishmania major trypanothione reductase 0.0053 0.0254 0.1192
Toxoplasma gondii exonuclease III APE 0.002 0.0026 0.0294
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0033 0.0118 0.0556
Brugia malayi Temporarily assigned gene name protein 44 0.0029 0.0089 0.039
Brugia malayi tailless protein 0.0022 0.004 0.0175
Schistosoma mansoni eukaryotic translation initiation factor 4e 0.0037 0.0143 0.0143
Schistosoma mansoni loxhd1 0.002 0.0029 0.0029
Brugia malayi succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 0.0022 0.004 0.0176
Brugia malayi hypothetical protein 0.0029 0.0088 0.0385
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0024 0.0055 0.0258
Schistosoma mansoni cation-transporting atpase fly 0.0017 0.0003 0.0003
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0144 0.0893 0.0893
Chlamydia trachomatis metal transport ATPase 0.0046 0.0204 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0006 0.003
Echinococcus multilocularis dnaJ subfamily B 0.086 0.5881 0.5881
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0024 0.0055 0.0258
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0024 0.0055 0.0615
Plasmodium vivax flavoprotein subunit of succinate dehydrogenase, putative 0.0022 0.004 0.0449
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0053 0.0255 0.0255
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0059 0.0301 0.0301
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0217 0.1402 0.1402
Echinococcus granulosus neutral alpha glucosidase AB 0.0039 0.0155 0.0155
Toxoplasma gondii E1-E2 ATPase subfamily protein 0.0063 0.0326 0.3652
Brugia malayi Steroid receptor seven-up type 2 0.0047 0.0211 0.0929
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0026 0.0123
Trypanosoma brucei NADH dehydrogenase 0.0034 0.0126 0.0593
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0155 0.0728
Echinococcus multilocularis cpg binding protein 0.0066 0.0346 0.0346
Trypanosoma brucei calcium motive p-type ATPase, putative 0.0116 0.0692 0.3251
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0175
Mycobacterium leprae N-Acetyl-1-D-myo-Inosityl-2-Amino-2-Deoxy-alpha-D-Glucopyranoside Deacetylase MshB (GlcNAc-Ins deacetylase) 0.0048 0.0218 0.018
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0057 0.0286 0.0286
Mycobacterium tuberculosis Probable fumarate reductase [flavoprotein subunit] FrdA (fumarate dehydrogenase) (fumaric hydrogenase) 0.0022 0.004 0.0024
Echinococcus multilocularis eukaryotic translation initiation factor 4E 0.0037 0.0143 0.0143
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0322 0.213 1
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.02 0.0473
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0099 0.0436
Leishmania major succinate dehydrogenase flavoprotein, putative 0.0022 0.004 0.0188
Trypanosoma brucei calcium-translocating P-type ATPase 0.0116 0.0692 0.3251
Brugia malayi Glycosyl hydrolases family 31 protein 0.0039 0.0155 0.0682
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0047 0.0211 0.0929
Trypanosoma cruzi ISWI complex protein 0.0016 0 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0206 0.0487
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0144 0.0893 0.4195
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0006 0.003
Toxoplasma gondii flavoprotein subunit of succinate dehydrogenase 0.0022 0.004 0.0449
Schistosoma mansoni sodium / potassium ATPase beta chain 0.0217 0.1402 0.1402
Echinococcus granulosus methyl CpG binding domain protein 2 0.0018 0.0013 0.0013
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0046 0.0204 0.0482
Schistosoma mansoni type V p-type atpase isoform 0.0046 0.0204 0.0204
Loa Loa (eye worm) hypothetical protein 0.0047 0.0211 0.0929
Onchocerca volvulus 0.0217 0.1402 0.7776
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0057 0.0286 0.0286
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0053 0.0258 0.1213
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0013 0.0013
Echinococcus granulosus lysosomal alpha glucosidase 0.0174 0.1097 0.1097
Plasmodium falciparum thioredoxin reductase 0.0024 0.0055 0.0615
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0024 0.0055 0.0039
Trypanosoma cruzi cation-transporting ATPase, putative 0.0046 0.0204 0.096
Plasmodium falciparum iron-sulfur subunit of succinate dehydrogenase 0.0052 0.0249 0.2791
Echinococcus granulosus CREB binding protein 0.0111 0.0663 0.0663
Brugia malayi acetyltransferase, GNAT family protein 0.0159 0.0993 0.4367
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0031 0.0099 0.1111
Trypanosoma brucei calcium-transporting ATPase, putative 0.0069 0.0369 0.1735
Plasmodium vivax P-type ATPase, putative 0.0017 0.0003 0.0037
Brugia malayi Nuclear hormone receptor-like 1 0.0025 0.0058 0.0256
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0053 0.0255 0.0255
Loa Loa (eye worm) calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0069 0.0369 0.1624
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0046 0.0206 0.231
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0026 0.0123
Trypanosoma cruzi proton motive ATPase 1, putative 0.0029 0.0088 0.0412
Brugia malayi polk-prov protein 0.0032 0.0111 0.0489
Loa Loa (eye worm) hypothetical protein 0.0031 0.0099 0.0436
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0046 0.0206 0.231
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0046 0.0206 0.0487
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0047 0.0211 0.0211
Trypanosoma brucei metacaspase 0.0046 0.0206 0.0969
Treponema pallidum cation-transporting ATPase, P-type 0.0046 0.0204 0.043
Trichomonas vaginalis sucrase-isomaltase, putative 0.0039 0.0155 0.0364
Loa Loa (eye worm) hypothetical protein 0.0049 0.0231 0.1014
Schistosoma mansoni caspase-3 (C14 family) 0.0121 0.0732 0.0732
Brugia malayi Probable calcium-transporting ATPase KIAA0703 0.0069 0.0369 0.1624
Schistosoma mansoni cation-transporting atpase worm 0.0046 0.0204 0.0204
Trypanosoma cruzi NADH dehydrogenase, putative 0.0034 0.0126 0.0593
Echinococcus granulosus dnaJ subfamily B 0.086 0.5881 0.5881
Schistosoma mansoni jumonji domain containing protein 0.0061 0.0312 0.0312
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.012 0.0721 0.0734
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0034 0.0126 0.011
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0024 0.0055 0.0258
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0144 0.0893 0.4195
Echinococcus granulosus copper transporting ATPase 1 0.0046 0.0204 0.0204
Schistosoma mansoni na+/k+ atpase alpha subunit 0.0116 0.0692 0.0692
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0326 0.0311
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0046 0.0206 0.0487
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0144 0.0893 0.2136
Schistosoma mansoni coup transcription factor 0.0047 0.0211 0.0211
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0063 0.0326 0.0775
Plasmodium vivax metacaspase 1, putative 0.0046 0.0206 0.231
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0053 0.0258 0.1135
Echinococcus granulosus protein quaking 0.0029 0.0089 0.0089
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0077 0.0427 0.2003
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0029 0.0326
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0055 0.0258
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0024 0.0055 0.0258
Echinococcus multilocularis nervana 2 0.0217 0.1402 0.1402
Brugia malayi hypothetical protein 0.0022 0.004 0.0175
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0025 0.0058 0.0058
Echinococcus granulosus Niemann Pick C1 protein 0.015 0.0932 0.0932
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0322 0.213 1
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0053 0.0258 0.1213
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.013 0.0792 0.0809
Schistosoma mansoni copper ABC transporter ATPase 0.0046 0.0204 0.0204
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.0144 0.0893 0.2136
Trichomonas vaginalis set domain proteins, putative 0.0275 0.1801 0.4316
Mycobacterium tuberculosis Conserved hypothetical protein 0.017 0.1068 0.1096
Trichomonas vaginalis STE family protein kinase 0.0077 0.0427 0.1016
Onchocerca volvulus 0.0217 0.1402 0.7776
Echinococcus multilocularis phosphoserine phosphatase 0.0029 0.0088 0.0088
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0047 0.0211 0.0929
Brugia malayi glutathione reductase 0.0053 0.0254 0.1116
Brugia malayi hypothetical protein 0.0043 0.0184 0.0811
Echinococcus multilocularis thyroid hormone receptor alpha 0.0047 0.0211 0.0211
Schistosoma mansoni steroid hormone receptor ad4bp 0.0047 0.0211 0.0211
Echinococcus multilocularis mitogen activated protein kinase 0.0053 0.0258 0.0258
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0077 0.0427 0.1875
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0016 0.0000020069 0.0000020069
Brugia malayi ecdysone receptor 0.0022 0.004 0.0175
Schistosoma mansoni rab6-interacting 0.002 0.0029 0.0029
Echinococcus granulosus succinate dehydrogenase (ubiquinone) iron sulfur 0.0052 0.0249 0.0249
Schistosoma mansoni polycystin 1-related 0.002 0.0029 0.0029
Plasmodium falciparum metacaspase 1 0.0046 0.0206 0.231
Loa Loa (eye worm) nuclear receptor NHR-67 0.0022 0.004 0.0175
Onchocerca volvulus Bile acid receptor homolog 0.0047 0.0211 0.1157
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0038 0.0153 0.0153
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0026 0.0055
Trypanosoma brucei succinate dehydrogenase iron-sulfur subunit 0.0029 0.0087 0.0409
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.005 0.0234 0.0553
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0026 0.0069 0.077
Trichomonas vaginalis DNA polymerase eta, putative 0.0043 0.0183 0.0432
Trypanosoma cruzi metacaspase 5, putative 0.0046 0.0206 0.0969
Loa Loa (eye worm) hypothetical protein 0.0045 0.02 0.0881
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0202 0.0949
Brugia malayi nuclear receptor RXR 0.0025 0.0058 0.0256
Plasmodium falciparum glutathione reductase 0.0024 0.0055 0.0615
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0206 0.0487
Brugia malayi Nuclear hormone receptor E75 0.0022 0.004 0.0175
Loa Loa (eye worm) hypothetical protein 0.0047 0.0211 0.0929
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0099 0.1111
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0154 0.172
Brugia malayi translation initiation factor 4E 0.0037 0.0143 0.0628
Loa Loa (eye worm) hypothetical protein 0.0047 0.0211 0.0929
Toxoplasma gondii proton ATPase, putative 0.0017 0.0003 0.0037
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0031 0.0099 0.0099
Brugia malayi phospholipid-translocating P-type ATPase, flippase family protein 0.0017 0.0003 0.0015
Schistosoma mansoni nuclear receptor nhr-48 0.0022 0.004 0.004
Schistosoma mansoni cellular tumor antigen P53 0.0051 0.0244 0.0244
Schistosoma mansoni phosphoserine phosphatase 0.0029 0.0088 0.0088
Trypanosoma brucei DNA polymerase IV, putative 0.0043 0.0183 0.0862
Leishmania major metacaspase, putative 0.0046 0.0206 0.0969
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0046 0.0206 0.231
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0037 0.0143 0.067
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0015
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0024 0.0055 0.004
Echinococcus multilocularis phospholipid transporting ATPase VA 0.0029 0.0088 0.0088
Leishmania major hypothetical protein, conserved 0.0016 0 0.0001
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.012 0.0721 0.0734
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0081 0.0454 0.1081
Onchocerca volvulus Protein ultraspiracle homolog 0.0047 0.0211 0.1157
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0047 0.0211 0.0929
Echinococcus granulosus nervana 2 0.0217 0.1402 0.1402
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.03 0.1979 0.1977
Echinococcus granulosus CREB binding protein 0.0071 0.0382 0.0382
Loa Loa (eye worm) histone methyltransferase 0.002 0.0026 0.0113
Brugia malayi hypothetical protein 0.002 0.0029 0.0128
Trichomonas vaginalis mercuric reductase, putative 0.0024 0.0055 0.0124
Toxoplasma gondii Copper-exporting ATPase 0.0017 0.0003 0.0037
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0026 0.0294
Mycobacterium tuberculosis Probable fumarate reductase [iron-sulfur subunit] FrdB (fumarate dehydrogenase) (fumaric hydrogenase) 0.0029 0.0087 0.0073
Plasmodium falciparum glutathione reductase 0.0053 0.0254 0.2842
Trypanosoma cruzi P-type H+-ATPase, putative 0.0092 0.0527 0.2476
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0026 0.0055
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0053 0.0258 0.1213
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0029 0.0088 0.0981
Loa Loa (eye worm) hypothetical protein 0.0029 0.0089 0.039
Schistosoma mansoni N-acetylglucosaminyl-phosphatidylinositol de-n-acetylase 0.0048 0.0218 0.0218
Trichomonas vaginalis cation-transporting ATPase, putative 0.0092 0.0527 0.1257
Brugia malayi Nuclear hormone receptor-like 1 0.0047 0.0211 0.0929
Echinococcus multilocularis calcium transporting atpase 0.0116 0.0692 0.0692
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0109 0.0644 0.0654
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0047 0.0211 0.0929
Mycobacterium ulcerans cation-transporter ATPase I CtpI 0.0098 0.057 0.0558
Echinococcus multilocularis lysosomal alpha glucosidase 0.0174 0.1097 0.1097
Brugia malayi nuclear hormone receptor family member nhr-6 0.0022 0.004 0.0175
Trypanosoma cruzi phospholipid-transporting ATPase 1-like protein, putative 0.0017 0.0003 0.0016
Echinococcus multilocularis Niemann Pick C1 protein 0.0105 0.0618 0.0618
Schistosoma mansoni inositol monophosphatase 0.0038 0.0154 0.0154
Giardia lamblia Phospholipid-transporting ATPase IA, putative 0.0046 0.0204 0.0482
Echinococcus multilocularis Na+:K+ ATPase alpha subunit 0.0116 0.0692 0.0692
Loa Loa (eye worm) hypothetical protein 0.0049 0.0228 0.1004
Loa Loa (eye worm) hypothetical protein 0.0025 0.0058 0.0256
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0047 0.0211 0.0929
Echinococcus multilocularis N acetylglucosaminyl phosphatidylinositol 0.0048 0.0218 0.0218
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.03 0.1979 0.1958
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0152 0.0948 0.4452
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0047 0.0211 0.0929
Mycobacterium ulcerans metal cation transporter ATPase p-type CtpE 0.0046 0.0204 0.0189
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0026 0.001
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0026 0.0123
Toxoplasma gondii thioredoxin reductase 0.0053 0.0254 0.2842
Echinococcus granulosus dna polymerase kappa 0.0043 0.0183 0.0183
Echinococcus granulosus caspase 0.0121 0.0732 0.0732
Echinococcus granulosus phospholipid transporting ATPase IF 0.0017 0.0003 0.0003
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0061 0.0312 0.0312
Onchocerca volvulus 0.0022 0.004 0.0203
Schistosoma mansoni type V p-type atpase isoform 0.0017 0.0003 0.0003
Trypanosoma brucei copper-transporting ATPase-like protein, putative 0.0046 0.0204 0.096
Schistosoma mansoni cpg binding protein 0.0066 0.0346 0.0346
Trypanosoma brucei phospholipid-translocating P-type ATPase (flippase), putative 0.0017 0.0003 0.0016
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0026 0.0065 0.0724
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0025 0.0058 0.0058
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0029 0.0088 0.0981
Echinococcus multilocularis phospholipid transporting ATPase IF 0.0017 0.0003 0.0003
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.035 0.035
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0063 0.0326 0.0326
Loa Loa (eye worm) hypothetical protein 0.0047 0.0211 0.0929
Echinococcus multilocularis copper transporting ATPase 1 0.0046 0.0204 0.0204
Onchocerca volvulus 0.0051 0.0241 0.1321
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0155 0.0364
Loa Loa (eye worm) CBP-B 0.0079 0.0439 0.1932
Leishmania major calcium-translocating P-type ATPase 0.0144 0.0893 0.4195
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0053 0.0253 0.1187
Echinococcus granulosus Ca2 transporting ATPase plasma membrane 0.0116 0.0692 0.0692
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0037 0.0143 0.0335
Trypanosoma cruzi phospholipid-transporting ATPase-like protein, putative 0.0029 0.0088 0.0412
Echinococcus multilocularis histone acetyltransferase MYST2 0.0058 0.029 0.029
Loa Loa (eye worm) PHD-finger family protein 0.0022 0.004 0.0175
Brugia malayi orphan nuclear receptor NR2E1 0.0022 0.004 0.0175
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0144 0.0893 1
Plasmodium falciparum metacaspase-like protein 0.0046 0.0206 0.231
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0116 0.0692 0.0692
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0175
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0022 0.0038 0.0038
Plasmodium falciparum copper-transporting ATPase 0.0046 0.0204 0.2288
Echinococcus multilocularis phospholipid transporting ATPase IIB 0.0046 0.0204 0.0204
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0155 0.0364
Brugia malayi hypothetical protein 0.0029 0.0089 0.039
Loa Loa (eye worm) hypothetical protein 0.0217 0.1402 0.6161
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0183 0.0862
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.0258 0.1213
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0116 0.0692 0.1653
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0039 0.0155 0.1737
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0046 0.0204 0.096
Leishmania major calcium-transporting ATPase, putative 0.0116 0.0692 0.3251
Brugia malayi calcium ATPase 0.0053 0.0253 0.1111
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0054 0.0263 0.0263
Loa Loa (eye worm) transbilayer Amphipath transporters family member 0.0017 0.0003 0.0015
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0047 0.0211 0.0929
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0031 0.0099 0.0436
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0024 0.0055 0.1285
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0034 0.0126 0.1413
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0047 0.0211 0.0211
Echinococcus granulosus plasma membrane calcium transporting ATPase 0.0116 0.0692 0.0692
Brugia malayi jmjC domain containing protein 0.0066 0.035 0.1538
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0046 0.0206 0.0907
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0206 0.0487
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0144 0.0893 0.2136
Echinococcus granulosus thioredoxin glutathione reductase 0.0053 0.0258 0.0258
Loa Loa (eye worm) hypothetical protein 0.0046 0.0204 0.0898
Trypanosoma cruzi succinate dehydrogenase iron-sulfur subunit 0.0033 0.0119 0.056
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0026 0.0055
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0242 0.157 0.6902
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0024 0.0055 0.0258
Loa Loa (eye worm) hypothetical protein 0.0029 0.0088 0.0387
Mycobacterium tuberculosis Probable reductase 0.0109 0.0644 0.0654
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0036 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0175
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0183 0.0862
Schistosoma mansoni microtubule-associated protein tau 0.1451 1 1
Schistosoma mansoni hypothetical protein 0.0029 0.0089 0.0089
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0615 0.417 1
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0144 0.0893 0.4195
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0041 0.0173 0.1937
Giardia lamblia Sgs1 DNA helicase, putative 0.0031 0.0099 0.023
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0154 0.0721
Trypanosoma cruzi metacaspase, putative 0.0046 0.0206 0.0969
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0024 0.0055 0.0615
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0217 0.1402 0.1402
Schistosoma mansoni cation-transporting ATPase 0.0046 0.0204 0.0204
Trypanosoma cruzi trypanothione reductase, putative 0.0053 0.0254 0.1192
Echinococcus granulosus calcium transporting atpase 0.0116 0.0692 0.0692
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0053 0.0258 0.1213
Trichomonas vaginalis cation-transporting ATPase, putative 0.0046 0.0204 0.0482
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0029 0.0029
Echinococcus multilocularis caspase 3 0.0075 0.0412 0.0412
Loa Loa (eye worm) hypothetical protein 0.0043 0.0184 0.0811
Brugia malayi TAZ zinc finger family protein 0.0111 0.0663 0.2916
Mycobacterium ulcerans hypothetical protein 0.017 0.1068 0.1059
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0024 0.0055 0.0258
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0034 0.0126 0.1413
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0116 0.0692 0.0692
Brugia malayi E1-E2 ATPase family protein 0.0092 0.0527 0.2317
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0047 0.0211 0.0211
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0053 0.0258 0.1213
Echinococcus multilocularis succinate dehydrogenase (ubiquinone) iron sulfur 0.0052 0.0249 0.0249
Schistosoma mansoni sex comb on midleg homolog 0.0051 0.0241 0.0241
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0144 0.0893 0.0893
Trichomonas vaginalis cation-transporting ATPase, putative 0.0144 0.0893 0.2136
Schistosoma mansoni CREB-binding protein 2 0.0111 0.0663 0.0663
Brugia malayi Bromodomain containing protein 0.0046 0.021 0.0924
Brugia malayi Pre-SET motif family protein 0.0036 0.0136 0.0598
Brugia malayi ecdysteroid receptor 0.0047 0.0211 0.0929
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0022 0.004 0.004
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0055 0.0258
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0059 0.0301 0.0287
Onchocerca volvulus 0.0043 0.0184 0.1007
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0063 0.0326 0.0322
Schistosoma mansoni nuclear hormone receptor 0.0022 0.004 0.004
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0051 0.0241 0.0241
Echinococcus multilocularis phosphoserine phosphatase 0.0029 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0105 0.0618 0.2716
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0025 0.0058 0.0058
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0144 0.0893 0.2136
Echinococcus granulosus phospholipid transporting atpase ih 0.0017 0.0003 0.0003
Schistosoma mansoni zinc finger protein 0.0022 0.004 0.004
Echinococcus multilocularis neuropeptide s receptor 0.0493 0.3321 0.3321
Schistosoma mansoni phospholipid-transporting atpase 0.0017 0.0003 0.0003
Echinococcus multilocularis nervana 2 0.0217 0.1402 0.1402
Leishmania major proton motive ATPase, putative 0.0046 0.0204 0.096
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.005 0.0234 0.2615
Schistosoma mansoni blooms syndrome DNA helicase 0.0028 0.0084 0.0084
Onchocerca volvulus 0.01 0.0586 0.3243
Mycobacterium leprae PROBABLE CATION-TRANSPORTER ATPASE I CTPI 0.0098 0.057 0.0536
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0031 0.0099 0.0099
Plasmodium vivax calcium-transporting ATPase, putative 0.0144 0.0893 1
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0029 0.0029
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0055 0.0258
Treponema pallidum fructose-bisphosphate aldolase 0.0615 0.417 1
Echinococcus multilocularis microtubule associated protein 2 0.1451 1 1
Brugia malayi nuclear receptor NHR-88 0.0022 0.004 0.0175
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0047 0.0211 0.0929
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0025 0.0058 0.0058
Onchocerca volvulus 0.0144 0.0893 0.4949
Mycobacterium ulcerans succinate dehydrogenase iron-sulfur subunit 0.0029 0.0087 0.0071
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0059 0.0301 0.0287
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0152 0.0948 0.4452
Trypanosoma brucei metacaspase MCA3 0.0046 0.0206 0.0969
Echinococcus granulosus expressed conserved protein 0.0099 0.0573 0.0573
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0038 0.0154 0.571
Schistosoma mansoni atpase class VI type 11c 0.0029 0.0088 0.0088
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0047 0.0211 0.0211
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0206 0.0487
Leishmania major P-type H -ATPase, putative 0.0092 0.0527 0.2476
Trypanosoma brucei succinate dehydrogenase iron-sulfur subunit, putative 0.0033 0.0119 0.056
Loa Loa (eye worm) acetyltransferase 0.0159 0.0993 0.4367
Echinococcus multilocularis caspase 2 0.0089 0.0504 0.0504
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0615 0.417 1
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0026 0.001
Onchocerca volvulus 0.0022 0.004 0.0203
Loa Loa (eye worm) nuclear hormone receptor 0.0022 0.004 0.0175
Echinococcus granulosus ecdysone induced protein 78C 0.0047 0.0211 0.0211
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0061 0.0312 0.0312
Schistosoma mansoni thyroid hormone receptor 0.0047 0.0211 0.0211
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0047 0.0211 0.0211
Schistosoma mansoni zinc finger protein 0.003 0.0095 0.0095
Loa Loa (eye worm) CXXC zinc finger family protein 0.006 0.0308 0.1352
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0073 0.0393 0.0393
Schistosoma mansoni inositol monophosphatase 0.0038 0.0154 0.0154
Wolbachia endosymbiont of Brugia malayi succinate dehydrogenase flavoprotein subunit 0.0022 0.004 0.062
Loa Loa (eye worm) hypothetical protein 0.0053 0.0253 0.1111
Echinococcus granulosus hypothetical protein 0.0029 0.0089 0.0089
Echinococcus multilocularis dual specificity mitogen activated protein 0.0077 0.0427 0.0427
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0183 0.0862
Echinococcus multilocularis CREB binding protein 0.0017 0.0007 0.0007
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0025 0.0058 0.0256
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0026 0.0123
Loa Loa (eye worm) hypothetical protein 0.0089 0.0504 0.2216
Trypanosoma brucei calcium-transporting ATPase, putative 0.0017 0.0003 0.0016
Trypanosoma cruzi metacaspase, putative 0.0046 0.0206 0.0969
Plasmodium vivax N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.0048 0.0218 0.2445
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0033 0.0118 0.0556
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0022 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0175
Echinococcus granulosus phospholipid transporting ATPase VA 0.0029 0.0088 0.0088
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0024 0.0055 0.0615
Echinococcus granulosus Protein patched homolog 1 0.0045 0.02 0.02
Loa Loa (eye worm) succinate-ubiquinone oxidoreductase 0.0022 0.004 0.0176
Loa Loa (eye worm) hypothetical protein 0.0025 0.0058 0.0256
Mycobacterium ulcerans succinate dehydrogenase flavoprotein subunit 0.0022 0.004 0.0024
Mycobacterium tuberculosis Probable succinate dehydrogenase [iron-sulfur subunit] (succinic dehydrogenase) 0.0022 0.004 0.0024
Entamoeba histolytica N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase, putative 0.0048 0.0218 0.0516
Mycobacterium tuberculosis Mycothiol conjugate amidase Mca (mycothiol S-conjugate amidase) 0.1395 0.9609 1
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0037 0.0143 0.0335
Schistosoma mansoni hypothetical protein 0.086 0.5881 0.5881
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0144 0.0893 0.4195
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0322 0.213 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0055 0.0258
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0047 0.0211 0.0929
Echinococcus granulosus tumor protein p63 0.035 0.2329 0.2329
Mycobacterium ulcerans N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB 0.0048 0.0218 0.0203
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0175
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0154 0.0154
Echinococcus granulosus phospholipid transporting ATPase IIB 0.0046 0.0204 0.0204
Brugia malayi MAP kinase sur-1 0.0053 0.0258 0.1135
Schistosoma mansoni alpha-glucosidase 0.0149 0.0928 0.0928
Schistosoma mansoni hypothetical protein 0.0043 0.0189 0.0189
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0047 0.0211 0.0211
Loa Loa (eye worm) hypothetical protein 0.0217 0.1402 0.6161
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0038 0.0153 0.0153
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0016 0.0000020069 0.0000020069
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0026 0.0055
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0022 0.0038 0.0038
Brugia malayi Cell death protein 3 precursor 0.0089 0.0504 0.2216
Echinococcus multilocularis plasma membrane calcium transporting ATPase 0.0116 0.0692 0.0692
Echinococcus granulosus caspase 2 0.0089 0.0504 0.0504
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0217 0.1402 0.1402
Echinococcus multilocularis sodium:potassium transporting ATPase subunit 0.0217 0.1402 0.1402
Loa Loa (eye worm) hypothetical protein 0.0046 0.0209 0.0921
Trichomonas vaginalis DNA helicase recq, putative 0.0033 0.0118 0.0276
Loa Loa (eye worm) hypothetical protein 0.0055 0.0267 0.1172
Echinococcus granulosus cation transporting atpase worm 0.0046 0.0204 0.0204
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0034 0.0126 0.1413
Plasmodium vivax hypothetical protein, conserved 0.0046 0.0206 0.231
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0217 0.1402 0.1402
Trypanosoma cruzi metacaspase 5, putative 0.0046 0.0206 0.0969
Echinococcus granulosus polycomb protein SCMH1 0.0051 0.0241 0.0241
Mycobacterium ulcerans mycothiol conjugate amidase Mca 0.1442 0.9941 1
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0058 0.029 0.029
Entamoeba histolytica recQ family helicase, putative 0.0033 0.0118 0.0276
Brugia malayi Inositol-1 0.0038 0.0154 0.0675
Echinococcus granulosus thyroid hormone receptor alpha 0.0022 0.004 0.004
Brugia malayi nuclear hormone receptor 0.0022 0.004 0.0175
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0144 0.0893 0.4195
Echinococcus multilocularis succinate dehydrogenase iron sulfur protein 0.0029 0.0087 0.0087
Echinococcus granulosus cpg binding protein 0.0066 0.0346 0.0346
Echinococcus granulosus lysine specific demethylase 5A 0.0066 0.035 0.035
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.0048 0.0218 0.1026
Schistosoma mansoni DNA helicase recq1 0.0031 0.0099 0.0099
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0033 0.0118 0.0118
Trichomonas vaginalis cation-transporting ATPase, putative 0.0144 0.0893 0.2136
Trypanosoma brucei Metacaspase-4 0.0046 0.0206 0.0969
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0047 0.0211 0.0929
Leishmania major aminophospholipid translocase, putative 0.0017 0.0003 0.0016
Echinococcus multilocularis tumor protein p63 0.035 0.2329 0.2329
Trypanosoma cruzi metacaspase, putative 0.0046 0.0206 0.0969
Loa Loa (eye worm) hypothetical protein 0.002 0.0029 0.0128
Schistosoma mansoni phospholipid-transporting atpase 0.0017 0.0003 0.0003
Brugia malayi CXXC zinc finger family protein 0.006 0.0308 0.1352
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0027 0.0078 0.0078
Plasmodium falciparum thioredoxin reductase 0.0053 0.0254 0.2842
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.035 0.035
Mycobacterium tuberculosis Possible metal cation transporting P-type ATPase CtpH 0.0098 0.057 0.0577
Loa Loa (eye worm) hypothetical protein 0.0047 0.0211 0.0929
Loa Loa (eye worm) phosphatidylinositol glycan anchor biosynthesis protein 0.0048 0.0218 0.096
Trypanosoma brucei Eukaryotic translation initiation factor 4E-1 0.0037 0.0143 0.067
Echinococcus granulosus histone acetyltransferase MYST2 0.0058 0.029 0.029
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0144 0.0893 0.2136
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.0048 0.0218 0.1026
Schistosoma mansoni ATPase 0.0144 0.0893 0.0893
Schistosoma mansoni cpg binding protein 0.006 0.0308 0.0308
Echinococcus multilocularis FTZ F1 alpha 0.0047 0.0211 0.0211
Loa Loa (eye worm) hypothetical protein 0.0046 0.0206 0.0907
Brugia malayi Bloom's syndrome protein homolog 0.0044 0.0192 0.0845
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0026 0.0026
Echinococcus multilocularis CREB binding protein 0.0078 0.0433 0.0433
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0037 0.0143 0.067
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0047 0.0211 0.0929
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0155 0.0364
Plasmodium falciparum flavoprotein subunit of succinate dehydrogenase 0.0022 0.004 0.0449
Brugia malayi CHE-14 protein 0.0045 0.02 0.0881
Echinococcus granulosus CREB binding protein 0.0017 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0046 0.0209 0.0921
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.0258 0.1213
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0098 0.057 0.2507
Brugia malayi hypothetical protein 0.0022 0.004 0.0175
Echinococcus granulosus SAM and MBT domain containing protein 0.0051 0.0241 0.0241
Schistosoma mansoni nuclear hormone receptor 0.0022 0.004 0.004
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0217 0.1402 0.1402
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0055 0.0271 0.1273
Echinococcus granulosus CREB binding protein 0.0017 0.0007 0.0007
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0055 0.0258
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0258 0.0612
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0047 0.0211 0.0929
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0046 0.0206 0.0487
Schistosoma mansoni cation-transporting atpase worm 0.0017 0.0003 0.0003
Schistosoma mansoni ap endonuclease 0.002 0.0026 0.0026
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0038 0.0154 0.0138
Echinococcus granulosus nervana 2 0.0217 0.1402 0.1402
Loa Loa (eye worm) glutathione reductase 0.0053 0.0254 0.1116
Loa Loa (eye worm) hypothetical protein 0.0054 0.0263 0.1154
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0031 0.0099 0.0099
Trypanosoma cruzi succinate dehydrogenase iron-sulfur subunit 0.0029 0.0087 0.0409
Loa Loa (eye worm) hypothetical protein 0.0058 0.029 0.1274
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0258 0.0612
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0059 0.0301 0.1324
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0144 0.0893 0.0893
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0081 0.0454 0.1994
Loa Loa (eye worm) succinate dehydrogenase iron-sulfur protein 0.0052 0.0249 0.1096
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0175
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0326 0.0311
Mycobacterium ulcerans DNA polymerase IV 0.0043 0.0183 0.0168
Loa Loa (eye worm) sodium potassium adenosine triphosphatase 0.0063 0.0326 0.1434
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0047 0.0211 0.0211
Echinococcus granulosus dual specificity mitogen activated protein 0.0077 0.0427 0.0427
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0144 0.0893 0.0893
Toxoplasma gondii plasma membrane-type Ca(2+)-ATPase A1 PMCAA1 0.0116 0.0692 0.775
Toxoplasma gondii eukaryotic initiation factor-4E, putative 0.0037 0.0143 0.1598
Trypanosoma cruzi plasma-membrane proton-efflux P-type ATPase, putative 0.0063 0.0326 0.1532
Echinococcus multilocularis lysosomal alpha glucosidase 0.0174 0.1097 0.1097
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0043 0.0183 0.0432
Trichomonas vaginalis DNA helicase recq1, putative 0.0044 0.0192 0.0454
Onchocerca volvulus Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial homolog 0.0022 0.004 0.0205
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0053 0.0255 0.0255
Loa Loa (eye worm) phospholipid-transporting ATPase ID 0.0017 0.0003 0.0015
Plasmodium vivax SET domain protein, putative 0.0036 0.0136 0.1522
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0217 0.1402 0.1402
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0026 0.0026
Leishmania major copper-transporting ATPase-like protein, putative 0.0046 0.0204 0.096
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0024 0.0055 0.0055
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0059 0.0301 0.0301
Brugia malayi Probable cation-transporting ATPase C10C6.6 in chromosome IV 0.0046 0.0204 0.0898
Echinococcus granulosus succinate dehydrogenase ubiquinone iron sulfur 0.0023 0.0049 0.0049
Mycobacterium ulcerans metal cation-transporting p-type ATPase CtpC 0.0046 0.0204 0.0189
Plasmodium falciparum phospholipid-transporting ATPase, putative 0.0017 0.0003 0.0037
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0022 0.004 0.0203
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0024 0.0055 0.0258
Trichomonas vaginalis STE family protein kinase 0.0077 0.0427 0.1016
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0029 0.0029
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0204 0.1311 0.1311
Echinococcus granulosus Nuclear hormone receptor HR96 0.0022 0.004 0.004
Plasmodium vivax P-type ATPase4, putative 0.0144 0.0893 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0046 0.0206 0.0487
Plasmodium falciparum cation-transporting ATPase 1 0.0017 0.0003 0.0037
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0046 0.0204 0.0482
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0217 0.1402 0.1402
Schistosoma mansoni RAR-like nuclear receptor 0.0047 0.0211 0.0211
Brugia malayi nuclear receptor NHR-88 0.0047 0.0211 0.0929
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0155 0.0364
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0047 0.0211 0.0211
Echinococcus granulosus neuropeptide s receptor 0.0493 0.3321 0.3321
Trypanosoma cruzi NADH dehydrogenase, putative 0.0034 0.0126 0.0593
Giardia lamblia Fructose-bisphosphate aldolase 0.0615 0.417 1
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0202 0.0949
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0046 0.0206 0.0487
Brugia malayi conserved hypotetical protein 0.0022 0.004 0.0175
Trypanosoma brucei phospholipid-transporting ATPase, putative 0.0017 0.0003 0.0016
Leishmania major P-type H -ATPase, putative 0.0092 0.0527 0.2476
Echinococcus multilocularis RUN 0.002 0.0029 0.0029
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0022 0.004 0.004
Plasmodium falciparum N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.0048 0.0218 0.2445
Echinococcus granulosus zinc finger protein 0.003 0.0095 0.0095
Loa Loa (eye worm) E1-E2 ATPase 0.0092 0.0527 0.2317
Loa Loa (eye worm) doublecortin family protein 0.002 0.0029 0.0128
Mycobacterium tuberculosis N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB (GlcNAc-Ins deacetylase) 0.0048 0.0218 0.021
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0183 0.0862
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0144 0.0893 0.2136
Leishmania major phospholipid-translocating P-type ATPase (flippase), putative 0.0017 0.0003 0.0016
Mycobacterium leprae PROBABLE CATION-TRANSPORTER P-TYPE ATPASE B CTPB 0.0046 0.0204 0.0166
Giardia lamblia Kinase, CMGC MAPK 0.0053 0.0258 0.0612
Giardia lamblia Histone acetyltransferase GCN5 0.0042 0.0177 0.0416
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0024 0.0055 0.0258
Brugia malayi mbt repeat family protein 0.0051 0.0241 0.1059
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0154 0.0361
Brugia malayi succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 0.0022 0.004 0.0176
Leishmania major alpha glucosidase II subunit, putative 0.0039 0.0155 0.0728
Trypanosoma brucei Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 0.0022 0.004 0.0188
Loa Loa (eye worm) hypothetical protein 0.0144 0.0893 0.3927
Onchocerca volvulus 0.0051 0.0244 0.1339
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0026 0.0116
Echinococcus granulosus N acetylglucosaminyl phosphatidylinositol 0.0048 0.0218 0.0218
Trypanosoma brucei phospholipid-translocating ATPase, putative 0.0017 0.0003 0.0016
Trypanosoma cruzi P-type H+-ATPase, putative 0.0092 0.0527 0.2476
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0107 0.0629 0.0629
Brugia malayi Niemann-Pick C1 protein precursor 0.0105 0.0618 0.2716
Plasmodium vivax cation transporting ATPase, putative 0.0046 0.0204 0.2288
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0073 0.0393 0.0393
Echinococcus granulosus Na:K ATPase alpha subunit 0.0116 0.0692 0.0692
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0048 0.0218 0.0516
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0059 0.0301 0.0297
Schistosoma mansoni myelin transcription factor 1 myt1 0.0058 0.029 0.029
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0258 0.0612
Echinococcus granulosus bloom syndrome protein 0.0044 0.0192 0.0192
Brugia malayi Potential phospholipid-transporting ATPase IA 0.0017 0.0003 0.0015
Trypanosoma brucei P-type H+-ATPase, putative 0.0092 0.0527 0.2476
Brugia malayi tumor suppressor. 0.0343 0.2275 1
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0206 0.0487
Brugia malayi PHD-finger family protein 0.0036 0.0135 0.0593
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0183 0.0862
Mycobacterium leprae Probable succinate dehydrogenase (iron-sulfur protein subunit) SdhB (SUCCINIC DEHYDROGENASE) (FUMARATE REDUCTASE) (FUMARATE DEHY 0.0029 0.0087 0.0048
Echinococcus multilocularis sterol regulatory element binding protein 0.0045 0.02 0.02
Echinococcus granulosus cation transporting ATPase 13A3 0.0046 0.0204 0.0204
Schistosoma mansoni hypothetical protein 0.0043 0.0184 0.0184
Toxoplasma gondii NADPH-glutathione reductase 0.0024 0.0055 0.0615
Brugia malayi calcium ATPase 0.0063 0.0326 0.1434
Mycobacterium tuberculosis Probable succinate dehydrogenase (iron-sulphur protein subunit) SdhB (succinic dehydrogenase) (fumarate reductase) (fumarate deh 0.0029 0.0087 0.0073
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0144 0.0893 0.2136
Plasmodium vivax phospholipid-transporting ATPase, putative 0.0017 0.0003 0.0037
Echinococcus multilocularis Niemann Pick C1 protein 0.015 0.0932 0.0932
Leishmania major phospholipid-transporting ATPase 1-like protein 0.0017 0.0003 0.0016

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) = 67 nM Effect on transactivation of ALP gene expression in HEK293 cells transfected with hERbeta ChEMBL. 16309907
EC50 (functional) = 67 nM Effect on transactivation of ALP gene expression in HEK293 cells transfected with hERbeta ChEMBL. 16309907
EC50 (functional) > 1000 nM Effect on transactivation of ALP gene expression in HEK293 cells transfected with hERalpha ChEMBL. 16309907
EC50 (functional) > 1000 nM Effect on transactivation of ALP gene expression in HEK293 cells transfected with hERalpha ChEMBL. 16309907
IC50 (binding) = 120 nM Inhibitory activity against AR ChEMBL. 16309907
IC50 (binding) = 120 nM Inhibitory activity against AR ChEMBL. 16309907
IC50 (binding) = 210 nM Binding affinity to human ERbeta ChEMBL. 16309907
IC50 (binding) = 210 nM Binding affinity to human ERbeta ChEMBL. 16309907
IC50 (binding) = 3984 nM Binding affinity to human ERalpha ChEMBL. 16309907
IC50 (binding) = 3984 nM Binding affinity to human ERalpha ChEMBL. 16309907
Ratio EC50 (functional) = 15 Selectivity for transactivation of ALP gene expression in HEK293 cells transfected with hERbeta over hERalpha ChEMBL. 16309907
Ratio EC50 (functional) = 15 Selectivity for transactivation of ALP gene expression in HEK293 cells transfected with hERbeta over hERalpha ChEMBL. 16309907
Ratio IC50 (binding) = 19 Selectivity for human ERbeta over ERalpha ChEMBL. 16309907
Ratio IC50 (binding) = 0.6 Selectivity for human ERbeta over AR ChEMBL. 16309907
Ratio IC50 (binding) = 19 Selectivity for human ERbeta over ERalpha ChEMBL. 16309907

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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