Detailed information for compound 37671

Basic information

Technical information
  • TDR Targets ID: 37671
  • Name: 5-amino-2-(2,6-dimethylphenyl)isoindole-1,3-d ione
  • MW: 266.295 | Formula: C16H14N2O2
  • H donors: 1 H acceptors: 2 LogP: 2.51 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: Nc1ccc2c(c1)C(=O)N(C2=O)c1c(C)cccc1C
  • InChi: 1S/C16H14N2O2/c1-9-4-3-5-10(2)14(9)18-15(19)12-7-6-11(17)8-13(12)16(18)20/h3-8H,17H2,1-2H3
  • InChiKey: URALYBWTMWGVCV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 5-amino-2-(2,6-dimethylphenyl)isoindoline-1,3-dione
  • 5-azanyl-2-(2,6-dimethylphenyl)isoindole-1,3-dione
  • 5-amino-2-(2,6-dimethylphenyl)isoindoline-1,3-quinone
  • 4-amino-N-(2,6-dimethylphenyl)phthalimide
  • 158276-70-1
  • AIDS-089078
  • AIDS089078
  • 1H-Isoindole-1,3(2H)-dione, 5-amino-2-(2,6-dimethylphenyl)-
  • 5-Amino-2-(2,6-dimethylphenyl)-1H-isoindole-1,3(2H)-dione
  • Add 213063
  • Add-213063

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis mercuric reductase, putative 0.0099 0.0877 0.1251
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0011 0.003 0.0087
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0012 0.0038 0.0038
Echinococcus granulosus serotonin transporter 0.0617 0.585 0.585
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0093 0.0818 0.3048
Echinococcus granulosus aldehyde dehydrogenase family 3 member B1 0.0011 0.003 0.003
Brugia malayi MH2 domain containing protein 0.0017 0.0092 0.0151
Schistosoma mansoni kinase 0.0097 0.0858 0.0858
Schistosoma mansoni acetylcholine receptor-related 0.0087 0.0765 0.0765
Schistosoma mansoni hypothetical protein 0.0009 0.0014 0.0014
Mycobacterium ulcerans pyrroline-5-carboxylate dehydrogenase, RocA 0.0011 0.003 0.0128
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0089 0.0779 0.0779
Entamoeba histolytica hypothetical protein 0.0011 0.0035 0.0164
Onchocerca volvulus 0.0734 0.6965 1
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0099 0.0877 0.0877
Brugia malayi G-protein coupled receptor 0.0009 0.0014 0.0023
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0099 0.0877 0.3267
Brugia malayi G protein-coupled receptor 0.0009 0.0014 0.0023
Giardia lamblia Sgs1 DNA helicase, putative 0.001 0.0018 0.0066
Brugia malayi glutathione reductase 0.0286 0.267 0.4369
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0026 0.0178 0.0644
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.0508 0.1884
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0169 0.1549 0.1549
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.009 0.0789 0.0789
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.015 0.0244
Echinococcus granulosus neuropeptide receptor 0.0009 0.0014 0.0014
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.011 0.0983 0.142
Toxoplasma gondii NADPH-glutathione reductase 0.0099 0.0877 0.3267
Schistosoma mansoni hypothetical protein 0.0011 0.003 0.003
Schistosoma mansoni nAChR subunit 0.0169 0.1549 0.1549
Loa Loa (eye worm) hypothetical protein 0.0012 0.0038 0.0062
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0617 0.585 0.9575
Echinococcus granulosus Ankyrin 0.0015 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Brugia malayi Serotonin receptor 0.0009 0.0014 0.0023
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.0257 0.036
Toxoplasma gondii aldehyde dehydrogenase 0.0197 0.1814 0.6787
Schistosoma mansoni netrin receptor unc5 0.0015 0.0066 0.0066
Echinococcus multilocularis 6 phosphofructokinase 0.011 0.0983 0.0983
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0035 0.0041
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Echinococcus multilocularis ETS transcription factor Elf 5 0.001 0.0025 0.0025
Brugia malayi glutamate synthase 0.0026 0.0178 0.0291
Trichomonas vaginalis CAMK family protein kinase 0.0191 0.1761 0.2521
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.0352 0.0576
Loa Loa (eye worm) hypothetical protein 0.0087 0.0765 0.1252
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0035 0.0041
Brugia malayi aldehyde dehydrogenase 0.0011 0.003 0.0048
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0099 0.0877 0.1265
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0105 0.0932 0.1524
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0211 0.0729
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0012 0.0038 0.0062
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0026 0.0178 0.0291
Echinococcus multilocularis serotonin receptor 0.0009 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0087 0.0765 0.1252
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0038 0.0038
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0105 0.0932 0.0931
Loa Loa (eye worm) G-protein coupled receptor 0.0009 0.0014 0.0023
Trichomonas vaginalis Phosphoglycerol transferase I, putative 0.0009 0.0009 0.0004
Giardia lamblia Hypothetical protein 0.0009 0.0009 0.0016
Echinococcus granulosus chromobox protein 1 0.0011 0.0035 0.0035
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0009 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0169 0.1549 0.2535
Loa Loa (eye worm) CHromoDomain protein family member 0.0013 0.0052 0.0085
Echinococcus granulosus 6 phosphofructokinase 0.011 0.0983 0.0983
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0011 0.0035 0.0108
Schistosoma mansoni nAChR subunit 0.0087 0.0765 0.0765
Onchocerca volvulus Protein ultraspiracle homolog 0.0012 0.0038 0.0055
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Loa Loa (eye worm) hypothetical protein 0.0082 0.071 0.1161
Loa Loa (eye worm) programmed cell death 8 0.0026 0.0178 0.0291
Echinococcus multilocularis sodium and chloride dependent glycine 0.0105 0.0932 0.0931
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Loa Loa (eye worm) hypothetical protein 0.0087 0.0765 0.1252
Echinococcus granulosus ewsr:fli fusion protein type 0.001 0.0025 0.0025
Schistosoma mansoni hypothetical protein 0.0026 0.0178 0.0178
Schistosoma mansoni chromobox protein 0.0011 0.0035 0.0035
Entamoeba histolytica aldehyde dehydrogenase 1, putative 0.0011 0.003 0.0132
Loa Loa (eye worm) hypothetical protein 0.002 0.0119 0.0195
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0099 0.0877 0.3267
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0197 0.1814 0.2628
Entamoeba histolytica hypothetical protein 0.0011 0.0035 0.0164
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0099 0.0877 0.3267
Loa Loa (eye worm) hypothetical protein 0.0105 0.0932 0.1524
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0004
Echinococcus multilocularis neuropeptide Y receptor 0.0009 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Onchocerca volvulus 0.0009 0.0014 0.002
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0072 0.0616 0.0886
Loa Loa (eye worm) hypothetical protein 0.0082 0.071 0.1161
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0105 0.0932 0.3473
Loa Loa (eye worm) hypothetical protein 0.0169 0.1549 0.2535
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0026 0.0178 0.095
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0035 0.0041
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0035 0.0041
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0012 0.0038 0.0062
Mycobacterium tuberculosis Probable sulfatase 0.0009 0.0009 0.0004
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Mycobacterium tuberculosis Possible arylsulfatase AtsA (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0009 0.0009 0.0004
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0115 0.0303
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0178 0.0644
Echinococcus multilocularis Chromo domain 0.0011 0.0035 0.0035
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0067 0.0067
Schistosoma mansoni opsin-like receptor 0.0009 0.0014 0.0014
Schistosoma mansoni serine/threonine protein kinase 0.0191 0.1761 0.1761
Echinococcus granulosus RUN 0.002 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0009 0.0009 0.0015
Loa Loa (eye worm) ets-domain-containing protein 0.001 0.0025 0.0041
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0011 0.0028 0.0028
Onchocerca volvulus 0.0105 0.0932 0.1337
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0092 0.0092
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0241 0.2237 0.2237
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0077 0.0662 0.0954
Loa Loa (eye worm) serotonin transporter b 0.0617 0.585 0.9575
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0073 0.0624 0.1021
Loa Loa (eye worm) hypothetical protein 0.0117 0.1052 0.1722
Loa Loa (eye worm) ACC-1 protein 0.0169 0.1549 0.2535
Mycobacterium tuberculosis Possible hydrolase 0.0009 0.0009 0.0004
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0169 0.1549 0.1549
Echinococcus multilocularis neuropeptide receptor 0.0009 0.0014 0.0014
Trypanosoma brucei DNA polymerase eta, putative 0.0043 0.0343 0.1264
Loa Loa (eye worm) hypothetical protein 0.0087 0.0765 0.1252
Brugia malayi Fli-1 protein 0.0216 0.2002 0.3276
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0106 0.0372
Onchocerca volvulus 0.0105 0.0932 0.1337
Mycobacterium tuberculosis Possible arylsulfatase AtsD (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0009 0.0009 0.0004
Echinococcus multilocularis g protein coupled receptor 0.0009 0.0014 0.0014
Trypanosoma cruzi DNA polymerase eta, putative 0.0043 0.0343 0.1264
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0009 0.0014 0.0014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0009 0.0014 0.0014
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0035 0.0164
Echinococcus granulosus 7tm_1 domain containing protein 0.0009 0.0014 0.0014
Schistosoma mansoni rab6-interacting 0.002 0.0115 0.0115
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0038 0.0038
Onchocerca volvulus 0.0009 0.0014 0.002
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0018 0.0029
Schistosoma mansoni biogenic amine receptor 0.0009 0.0014 0.0014
Brugia malayi hypothetical protein 0.0009 0.0014 0.0023
Echinococcus multilocularis dro:myosuppressin receptor 0.0009 0.0014 0.0014
Echinococcus multilocularis glycine receptor subunit beta 0.0169 0.1549 0.1549
Echinococcus multilocularis geminin 0.105 1 1
Echinococcus granulosus Chromo domain 0.0011 0.0035 0.0035
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0066 0.0107
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0009 0.0014 0.0014
Echinococcus granulosus cpg binding protein 0.0032 0.0233 0.0232
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0011 0.003 0.0087
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0009 0.0014 0.0014
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.011 0.0983 0.3667
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0004
Entamoeba histolytica phosphofructokinase, putative 0.011 0.0983 0.5567
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0106 0.0372
Echinococcus multilocularis allatostatin A receptor 0.0009 0.0014 0.0014
Schistosoma mansoni hypothetical protein 0.0011 0.0035 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0004
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0068 0.0574 0.0574
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0037 0.028 0.0458
Schistosoma mansoni biogenic amine (5HT) receptor 0.0009 0.0014 0.0014
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0012 0.0038 0.0038
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.011 0.0983 0.1638
Loa Loa (eye worm) MH2 domain-containing protein 0.0255 0.2368 0.3875
Trichomonas vaginalis mucin-desulfating sulfatase, putative 0.0009 0.0009 0.0004
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0009 0.0014 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0004
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0101 0.0136
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0026 0.0178 0.0291
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0009 0.0014 0.0023
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0105 0.0932 0.0931
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Echinococcus multilocularis thioredoxin glutathione reductase 0.0286 0.2675 0.2675
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0026 0.0178 0.0178
Loa Loa (eye worm) nuclear factor I 0.001 0.0018 0.0029
Schistosoma mansoni biogenic amine receptor 0.0009 0.0014 0.0014
Brugia malayi Tachykinin-like peptides receptor 99D 0.0009 0.0014 0.0023
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0009 0.0014 0.0014
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0013 0.0052 0.0052
Loa Loa (eye worm) norepinephrine transporter 0.0617 0.585 0.9575
Echinococcus multilocularis neuropeptide Y receptor 0.0009 0.0014 0.0014
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0106 0.0372
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0106 0.0142
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0834 0.119
Schistosoma mansoni gabp alpha 0.0071 0.061 0.061
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0178 0.0644
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0011 0.0035 0.0035
Echinococcus multilocularis chromobox protein 2 0.0011 0.0035 0.0035
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0241 0.2237 0.3662
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0026 0.0178 0.0644
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0026 0.0178 0.0644
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0004
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0038 0.0062
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0197 0.1814 0.1814
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0035 0.0041
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0026 0.0178 0.025
Echinococcus granulosus rhodopsin orphan GPCR 0.0009 0.0014 0.0014
Echinococcus granulosus sodium and chloride dependent glycine 0.0105 0.0932 0.0931
Mycobacterium ulcerans aldehyde dehydrogenase (NAD+) dependent 0.0011 0.003 0.0128
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0026 0.0178 0.0978
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0009 0.0014 0.0023
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0026 0.0178 0.025
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0004
Schistosoma mansoni polycystin 1-related 0.002 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0013 0.0052 0.0052
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0012 0.0038 0.0038
Brugia malayi hypothetical protein 0.0009 0.0014 0.0023
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0013 0.0052 0.0052
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.008 0.0696 0.259
Brugia malayi steroid hormone receptor 0.0012 0.0038 0.0062
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0101 0.0136
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0026 0.0178 0.1753
Schistosoma mansoni hypothetical protein 0.001 0.0025 0.0025
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0011 0.0035 0.0051
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0352 0.0352
Schistosoma mansoni nAChR subunit 0.0169 0.1549 0.1549
Loa Loa (eye worm) hypothetical protein 0.0169 0.1549 0.2535
Echinococcus multilocularis rhodopsin orphan GPCR 0.0009 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0322 0.3012 0.4929
Treponema pallidum NADH oxidase 0.0099 0.0877 0.1455
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0352 0.0352
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0009 0.0014 0.0014
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0169 0.1549 0.2535
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0038 0.0062
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0105 0.0932 1
Brugia malayi ORL1-like opioid receptor 0.0009 0.0014 0.0023
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0035 0.0164
Trypanosoma brucei trypanothione reductase 0.0286 0.267 1
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0082 0.071 0.071
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0026 0.0178 0.0178
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0106 0.0106
Schistosoma mansoni nAChR subunit 0.0169 0.1549 0.1549
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0009 0.0014 0.0014
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0011 0.003 0.0087
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0035 0.0041
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0009 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0043 0.0343 0.0561
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0009 0.0014 0.0014
Schistosoma mansoni ets 0.001 0.0025 0.0025
Echinococcus granulosus neuropeptide receptor 0.0009 0.0014 0.0014
Brugia malayi Dopamine receptor 0.0009 0.0014 0.0023
Schistosoma mansoni biogenic amine receptor 0.0009 0.0014 0.0014
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0026 0.0178 0.0644
Schistosoma mansoni neuropeptide F-like receptor 0.0009 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.002 0.0115 0.0188
Echinococcus multilocularis GA binding protein alpha chain 0.0071 0.061 0.0609
Echinococcus granulosus lamin dm0 0.0086 0.0754 0.0754
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0009 0.0014 0.0014
Trichomonas vaginalis DNA helicase recq1, putative 0.0023 0.015 0.0206
Loa Loa (eye worm) hypothetical protein 0.0169 0.1549 0.2535
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0009 0.0014 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0004
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0093 0.0818 0.0818
Giardia lamblia DINP protein human, muc B family 0.0019 0.0106 0.0565
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0099 0.0877 0.3267
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0087 0.0765 0.0765
Echinococcus granulosus glycine receptor subunit alpha 1 0.0169 0.1549 0.1549
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0191 0.1761 0.1761
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0026 0.0178 0.0291
Loa Loa (eye worm) acetylcholine receptor protein 0.0087 0.0765 0.1252
Onchocerca volvulus 0.0009 0.0014 0.002
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0026 0.0178 0.0542
Loa Loa (eye worm) hypothetical protein 0.001 0.0025 0.0041
Loa Loa (eye worm) hypothetical protein 0.0011 0.0035 0.0058
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0101 0.0136
Plasmodium vivax glutathione reductase, putative 0.0286 0.267 1
Plasmodium falciparum thioredoxin reductase 0.0099 0.0877 0.3238
Schistosoma mansoni aldehyde dehydrogenase 0.0197 0.1814 0.1814
Schistosoma mansoni sodium/chloride dependent transporter 0.0105 0.0932 0.0932
Leishmania major aldehyde dehydrogenase, putative 0.0011 0.003 0.0087
Onchocerca volvulus 0.0009 0.0014 0.002
Loa Loa (eye worm) hypothetical protein 0.0105 0.0932 0.1524
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0004
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0115 0.0115
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0105 0.0932 0.1524
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0071 0.0092
Mycobacterium tuberculosis Probable reductase 0.0652 0.6185 0.8984
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0115 0.0115
Echinococcus multilocularis nAChR subunit 0.0082 0.071 0.071
Loa Loa (eye worm) TYRA-2 protein 0.0009 0.0014 0.0023
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0035 0.0041
Brugia malayi excitatory GABA receptor EXP-1A 0.0169 0.1549 0.2535
Brugia malayi hypothetical protein 0.0087 0.0765 0.1252
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0026 0.0178 0.0247
Schistosoma mansoni lipoxygenase 0.0083 0.0718 0.0718
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0652 0.6185 0.8984
Echinococcus granulosus ATP dependent DNA helicase Q1 0.001 0.0018 0.0018
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0009 0.0014 0.0023
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0169 0.1549 0.1549
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0011 0.003 0.003
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0026 0.0178 0.025
Schistosoma mansoni hypothetical protein 0.0072 0.062 0.062
Schistosoma mansoni adenoreceptor 0.0009 0.0014 0.0014
Loa Loa (eye worm) doublecortin family protein 0.002 0.0115 0.0188
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0106 0.0548
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0169 0.1549 0.1549
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0211 0.0295
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0026 0.0178 0.0178
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0009 0.0014 0.0014
Echinococcus granulosus dna polymerase kappa 0.0019 0.0106 0.0106
Mycobacterium ulcerans glutamate synthase subunit beta 0.0026 0.0178 0.095
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0011 0.0035 0.0035
Echinococcus multilocularis neuropeptides capa receptor 0.0009 0.0014 0.0014
Giardia lamblia Kinase, PLK 0.0191 0.1761 1
Mycobacterium ulcerans arylsulfatase AtsD 0.0009 0.0009 0.0015
Loa Loa (eye worm) hypothetical protein 0.0082 0.071 0.1161
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Loa Loa (eye worm) hypothetical protein 0.0077 0.0662 0.1084
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0026 0.0178 0.0644
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0004
Trypanosoma brucei unspecified product 0.0019 0.0106 0.0372
Brugia malayi hypothetical protein 0.0009 0.0014 0.0023
Brugia malayi Associated with TFs and helicases family protein 0.0011 0.0035 0.0058
Plasmodium falciparum glutathione reductase 0.0286 0.267 1
Loa Loa (eye worm) hypothetical protein 0.0169 0.1549 0.2535
Toxoplasma gondii methylmalonate-semialdehyde dehydrogenase [acylating], putative 0.0011 0.003 0.0087
Loa Loa (eye worm) hypothetical protein 0.0105 0.0932 0.1524
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0191 0.1761 0.6587
Echinococcus multilocularis lamin dm0 0.0086 0.0754 0.0754
Echinococcus granulosus chromobox protein 2 0.0011 0.0035 0.0035
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0011 0.0035 0.0035
Onchocerca volvulus 0.06 0.568 0.8155
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0169 0.1549 0.2535
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0099 0.0877 0.4814
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0241 0.2237 0.2237
Onchocerca volvulus 0.0009 0.0014 0.002
Mycobacterium ulcerans hydrolase 0.0009 0.0009 0.0015
Echinococcus multilocularis g-protein coupled receptor 0.0009 0.0014 0.0014
Schistosoma mansoni cpg binding protein 0.0032 0.0233 0.0233
Echinococcus granulosus rhodopsin orphan GPCR 0.0009 0.0014 0.0014
Schistosoma mansoni aldehyde dehydrogenase 0.0011 0.003 0.003
Giardia lamblia NADH oxidase lateral transfer candidate 0.0099 0.0877 0.496
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0082 0.071 0.1161
Loa Loa (eye worm) intermediate filament protein 0.0086 0.0754 0.1234
Echinococcus granulosus g protein coupled receptor 0.0009 0.0014 0.0014
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0012 0.0038 0.0055
Mycobacterium ulcerans endonuclease IV 0.0077 0.0662 0.3628
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0035 0.0041
Loa Loa (eye worm) hypothetical protein 0.0512 0.4841 0.7922
Trichomonas vaginalis DNA helicase recq, putative 0.0012 0.0045 0.0056
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0099 0.0877 0.3193
Brugia malayi Doublecortin family protein 0.002 0.0115 0.0188
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0169 0.1549 0.2535
Onchocerca volvulus 0.0009 0.0014 0.002
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0013 0.0048 0.0048
Echinococcus granulosus 7TM GPCR rhodopsin 0.0009 0.0014 0.0014
Brugia malayi G-protein coupled receptor 0.0009 0.0014 0.0023
Loa Loa (eye worm) hypothetical protein 0.004 0.031 0.0508
Brugia malayi Heterochromatin protein 1 0.0011 0.0035 0.0058
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0211 0.0295
Giardia lamblia Thioredoxin reductase 0.0026 0.0178 0.0978
Echinococcus granulosus ATP dependent DNA helicase Q5 0.001 0.0018 0.0018
Schistosoma mansoni neuropeptide receptor 0.0009 0.0014 0.0014
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.0983 0.1404
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0082 0.071 0.1161
Echinococcus granulosus glycine receptor subunit beta 0.0169 0.1549 0.1549
Schistosoma mansoni ets-related 0.001 0.0025 0.0025
Brugia malayi MH1 domain containing protein 0.0017 0.0092 0.0151
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0009 0.0014 0.0014
Plasmodium falciparum thioredoxin reductase 0.0286 0.267 1
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0011 0.0035 0.0108
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.009 0.0789 0.0789
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0004
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0087 0.0765 0.1252
Schistosoma mansoni voltage-gated potassium channel 0.004 0.0313 0.0313
Schistosoma mansoni inositol monophosphatase 0.008 0.0696 0.0696
Toxoplasma gondii endonuclease IV APN 0.0077 0.0662 0.2462
Loa Loa (eye worm) hypothetical protein 0.0085 0.0739 0.1209
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0004
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0009 0.0014 0.0014
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0106 0.0372
Echinococcus granulosus alpha 1A adrenergic receptor 0.0009 0.0014 0.0014
Echinococcus granulosus glycine receptor subunit alpha 1 0.0169 0.1549 0.1549
Echinococcus multilocularis cpg binding protein 0.0032 0.0233 0.0232
Echinococcus granulosus glutamate synthase 0.0026 0.0178 0.0178
Loa Loa (eye worm) hypothetical protein 0.0011 0.003 0.0048
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Trypanosoma cruzi trypanothione reductase, putative 0.0099 0.0877 0.3267
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0035 0.0041
Schistosoma mansoni cpg binding protein 0.0032 0.0233 0.0233
Schistosoma mansoni neurotransmitter gated ion channel 0.0087 0.0765 0.0765
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0026 0.0178 0.095
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0092 0.0092
Echinococcus multilocularis rhodopsin orphan GPCR 0.0009 0.0014 0.0014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0012 0.0038 0.0062
Leishmania major NADH dehydrogenase, putative 0.0026 0.0178 0.0644
Schistosoma mansoni hypothetical protein 0.002 0.0115 0.0115
Schistosoma mansoni retinoic acid receptor RXR 0.0012 0.0038 0.0038
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0066 0.0065
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Entamoeba histolytica myo-inositol monophosphatase, putative 0.008 0.0696 0.3933
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0013 0.0048 0.0048
Mycobacterium ulcerans sulfatase 0.0009 0.0009 0.0015
Echinococcus multilocularis glycine receptor subunit beta 0.0169 0.1549 0.1549
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0352 0.0352
Schistosoma mansoni neurotransmitter gated ion channel 0.0082 0.071 0.071
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0105 0.0932 0.1524
Trichomonas vaginalis CAMK family protein kinase 0.0191 0.1761 0.2521
Echinococcus multilocularis fmrfamide receptor 0.0009 0.0014 0.0014
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0026 0.0178 0.025
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0087 0.0765 0.0765
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0211 0.0729
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0004
Trichomonas vaginalis CAMK family protein kinase 0.0191 0.1761 0.2521
Mycobacterium tuberculosis Probable oxidoreductase 0.0725 0.6883 1
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0211 0.0295
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.06 0.568 0.568
Mycobacterium ulcerans piperideine-6-carboxilic acid dehydrogenase Pcd 0.0011 0.003 0.0128
Schistosoma mansoni glutamate synthase 0.0026 0.0178 0.0178
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0106 0.0106
Onchocerca volvulus 0.0087 0.0765 0.1098
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0106 0.0548
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.008 0.0696 0.259
Brugia malayi hypothetical protein 0.002 0.0115 0.0188
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0004
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0169 0.1549 0.2535
Trypanosoma brucei unspecified product 0.0013 0.005 0.0163
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0115 0.0115
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0092 0.0092
Onchocerca volvulus Serine\/threonine kinase homolog 0.0191 0.1761 0.2528
Plasmodium falciparum glutathione reductase 0.0099 0.0877 0.3238
Echinococcus multilocularis Smad4 0.0017 0.0092 0.0092
Loa Loa (eye worm) G-protein coupled receptor 0.0009 0.0014 0.0023
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0652 0.6185 0.8984
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0026 0.0178 0.0644
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0011 0.003 0.0087
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0012 0.0038 0.0062
Mycobacterium tuberculosis Probable pyrroline-5-carboxylate dehydrogenase RocA 0.0011 0.003 0.0034
Brugia malayi Thioredoxin reductase 0.0286 0.267 0.4369
Entamoeba histolytica hypothetical protein 0.0072 0.062 0.3496
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0038 0.0062
Loa Loa (eye worm) hypothetical protein 0.0169 0.1549 0.2535
Echinococcus granulosus g-protein coupled receptor 0.0009 0.0014 0.0014
Echinococcus granulosus tm gpcr rhodopsin 0.0009 0.0014 0.0014
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0087 0.0765 0.0765
Leishmania major hypothetical protein, conserved 0.0026 0.0178 0.0644
Echinococcus granulosus inositol monophosphatase 1 0.008 0.0696 0.0696
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0045 0.0146
Loa Loa (eye worm) thioredoxin reductase 0.0286 0.267 0.4369
Echinococcus granulosus sodium and chloride dependent glycine 0.0105 0.0932 0.0931
Loa Loa (eye worm) hypothetical protein 0.0011 0.0035 0.0058
Onchocerca volvulus 0.0009 0.0014 0.002
Schistosoma mansoni transcription factor LCR-F1 0.0072 0.062 0.062
Schistosoma mansoni hypothetical protein 0.0008 0.0007 0.0007
Entamoeba histolytica recQ family helicase, putative 0.0012 0.0045 0.0221
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0009 0.0014 0.0014
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0026 0.0178 0.0644
Schistosoma mansoni sodium/chloride dependent transporter 0.0105 0.0937 0.0937
Schistosoma mansoni biogenic amine (5HT) receptor 0.0009 0.0014 0.0014
Brugia malayi Steroid receptor seven-up type 2 0.0012 0.0038 0.0062
Brugia malayi SET domain containing protein 0.0015 0.0074 0.0121
Loa Loa (eye worm) transcription factor SMAD2 0.0255 0.2368 0.3875
Loa Loa (eye worm) aldehyde dehydrogenase 0.0011 0.003 0.0048
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0352 0.0352
Schistosoma mansoni amine GPCR 0.0009 0.0014 0.0014
Brugia malayi Protein kinase domain containing protein 0.0015 0.0072 0.0117
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0037 0.028 0.028
Echinococcus multilocularis rhodopsin orphan GPCR 0.0009 0.0014 0.0014
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0011 0.003 0.0087
Echinococcus multilocularis g protein coupled receptor 0.0009 0.0014 0.0014
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0087 0.0765 0.0765
Echinococcus granulosus chromobox protein 1 0.0011 0.0035 0.0035
Loa Loa (eye worm) histone methyltransferase 0.0013 0.0048 0.0079
Schistosoma mansoni chromobox protein 0.0011 0.0035 0.0035
Schistosoma mansoni DNA helicase recq1 0.001 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Chlamydia trachomatis endonuclease IV 0.0077 0.0662 0.7089
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0118 0.1059 0.1059
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0035 0.0041
Loa Loa (eye worm) hypothetical protein 0.001 0.0025 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0035 0.0041
Brugia malayi Dopamine receptor protein 1 0.0009 0.0014 0.0023
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0073 0.0624 0.1021
Onchocerca volvulus 0.0009 0.0014 0.002
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0009 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0032 0.0233 0.0382
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0012 0.0038 0.0038
Echinococcus granulosus serotonin receptor 0.0009 0.0014 0.0014
Echinococcus granulosus rhodopsin orphan GPCR 0.0009 0.0014 0.0014
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0216 0.0353
Brugia malayi cytoplasmic intermediate filament protein 0.0046 0.037 0.0605
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0105 0.0932 0.0932
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0026 0.0178 0.025
Echinococcus multilocularis G-protein coupled receptor, putative 0.0009 0.0014 0.0014
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0211 0.0769
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0018 0.0044
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0099 0.0877 0.3267
Trichomonas vaginalis inositol monophosphatase, putative 0.008 0.0696 0.0992
Echinococcus multilocularis voltage gated potassium channel 0.0011 0.0028 0.0028
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0352 0.0352
Mycobacterium ulcerans monoxygenase 0.0026 0.0178 0.095
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0099 0.0877 0.3193
Echinococcus granulosus synaptic vesicular amine transporter 0.0382 0.3591 0.3591
Loa Loa (eye worm) phosphofructokinase 0.011 0.0983 0.1609
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0026 0.0178 0.0644
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0009 0.0014 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0004
Brugia malayi neuropeptide F receptor 0.0009 0.0014 0.0023
Onchocerca volvulus 0.002 0.0115 0.0165
Brugia malayi hypothetical protein 0.002 0.0115 0.0188
Treponema pallidum thioredoxin reductase (trxB) 0.0026 0.0178 0.0255
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0037 0.028 0.028
Echinococcus granulosus intermediate filament protein 0.0086 0.0754 0.0754
Echinococcus granulosus g protein coupled receptor 0.0009 0.0014 0.0014
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0011 0.0035 0.0035
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0099 0.0877 0.0876
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0352 0.0352
Echinococcus granulosus ETS transcription factor Elf 2 0.001 0.0025 0.0025
Schistosoma mansoni nAChR subunit 0.0169 0.1549 0.1549
Onchocerca volvulus 0.003 0.0216 0.031
Echinococcus multilocularis nAChR subunit 0.0169 0.1549 0.1549
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0026 0.0178 0.0247
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0211 0.0668
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0011 0.003 0.003
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0026 0.0178 0.0978
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0106 0.0144
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.005 0.0163
Brugia malayi putative neuropeptide receptor 0.0009 0.0014 0.0023
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0011 0.003 0.0087
Mycobacterium ulcerans hypothetical protein 0.0026 0.0178 0.095
Echinococcus multilocularis synaptic vesicular amine transporter 0.0382 0.3591 0.3591
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0169 0.1549 0.2535
Loa Loa (eye worm) hypothetical protein 0.0087 0.0765 0.1252
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0009 0.0014 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0004
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0009 0.0014 0.0014
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0009 0.0014 0.0014
Mycobacterium ulcerans aldehyde dehydrogenase 0.0197 0.1814 1
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0169 0.1549 0.2535
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.008 0.0696 0.7872
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0211 0.2215
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0011 0.0035 0.0051
Brugia malayi MH2 domain containing protein 0.0017 0.0092 0.0151
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0241 0.2237 0.2237
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0169 0.1549 0.2535
Schistosoma mansoni nAChR subunit 0.0169 0.1549 0.1549
Toxoplasma gondii aldehyde dehydrogenase (NAD) family protein 0.0011 0.003 0.0087
Schistosoma mansoni aldehyde dehydrogenase 0.0197 0.1814 0.1814
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0026 0.0178 0.0644
Leishmania major aldehyde dehydrogenase, putative 0.0011 0.003 0.0087
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0026 0.0178 0.0542
Echinococcus granulosus orexin receptor type 2 0.0009 0.0014 0.0014
Brugia malayi M-phase phosphoprotein, mpp8 0.0101 0.0899 0.1471
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0012 0.0038 0.0062
Mycobacterium tuberculosis Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialde 0.0011 0.003 0.0034
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0009 0.0014 0.0023
Toxoplasma gondii selenide, water dikinase 0.0026 0.0178 0.0644
Loa Loa (eye worm) 6-phosphofructokinase 0.011 0.0983 0.1609
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0004
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0169 0.1549 0.1549
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0169 0.1549 0.1549
Brugia malayi Protein cec-1. 0.0011 0.0035 0.0058
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0211 0.0295
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0038 0.0038
Trypanosoma brucei polo-like protein kinase 0.0191 0.1761 0.6587
Trichomonas vaginalis CAMK family protein kinase 0.0191 0.1761 0.2521
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0197 0.1814 0.6787
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0072 0.0616 0.0886
Schistosoma mansoni lamin 0.0086 0.0754 0.0754
Loa Loa (eye worm) neuropeptide F receptor 0.0009 0.0014 0.0023
Schistosoma mansoni nuclear hormone receptor 0.0012 0.0038 0.0038
Schistosoma mansoni smad1 5 8 and 0.0017 0.0092 0.0092
Brugia malayi CXXC zinc finger family protein 0.003 0.0216 0.0353
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0026 0.0178 0.025
Echinococcus multilocularis ETS domain containing protein Elk 1 0.001 0.0025 0.0025
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0072 0.062 0.062
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0115 0.0115
Brugia malayi AKH receptor 0.0009 0.0014 0.0023
Echinococcus granulosus neuropeptide Y receptor 0.0009 0.0014 0.0014
Echinococcus granulosus rhodopsin orphan GPCR 0.0009 0.0014 0.0014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0009 0.0014 0.0014
Echinococcus granulosus succinate semialdehyde dehydrogenase 0.0011 0.003 0.003
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.06 0.568 0.568
Schistosoma mansoni hypothetical protein 0.001 0.0025 0.0025
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0009 0.0014 0.0014
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0011 0.003 0.0128
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.0009 0.0009 0.0013
Plasmodium falciparum amino acid transporter, putative 0.0105 0.0932 0.3445
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0169 0.1549 0.1549
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0011 0.003 0.0132
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0011 0.0035 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0004
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0026 0.0178 0.0178
Brugia malayi nuclear receptor NHR-88 0.0012 0.0038 0.0062
Brugia malayi hypothetical protein 0.0009 0.0014 0.0023
Brugia malayi intermediate filament protein 0.0086 0.0754 0.1234
Brugia malayi Succinate semialdehyde dehydrogenase, mitochondrial precursor 0.0011 0.003 0.0048
Brugia malayi hypothetical protein 0.0105 0.0932 0.1524
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0026 0.0178 0.0644
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0119 0.0164
Schistosoma mansoni vesicular amine transporter 0.0382 0.3591 0.3591
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0035 0.0041
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0106 0.0372
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0011 0.003 0.0087
Mycobacterium leprae PROBABLE GAMMA-GLUTAMYL PHOSPHATE REDUCTASE PROTEIN PROA (GPR) (GLUTAMATE-5-SEMIALDEHYDE DEHYDROGENASE) (GLUTAMYL-GAMMA-SEMIALDE 0.0011 0.003 0.0034
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0026 0.0178 0.095
Trichomonas vaginalis myo inositol monophosphatase, putative 0.008 0.0696 0.0992
Brugia malayi Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor 0.0011 0.003 0.0048
Loa Loa (eye worm) hypothetical protein 0.0012 0.0038 0.0062
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0009 0.0014 0.0023
Echinococcus multilocularis fmrfamide receptor 0.0009 0.0014 0.0014
Toxoplasma gondii hypothetical protein 0.0105 0.0932 0.3473
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0105 0.0932 0.3473
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0009 0.0014 0.0014
Schistosoma mansoni chromobox protein 0.0011 0.0035 0.0035
Brugia malayi hypothetical protein 0.0102 0.09 0.1473
Brugia malayi MH2 domain containing protein 0.0255 0.2368 0.3875
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0105 0.0932 0.0931
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0169 0.1549 0.2535
Loa Loa (eye worm) hypothetical protein 0.0082 0.071 0.1161
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0012 0.0038 0.0062
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0093 0.0818 0.0818
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0038 0.0038
Schistosoma mansoni disulfide oxidoreductase 0.0026 0.0178 0.0178
Leishmania major DNA polymerase eta, putative 0.0043 0.0343 0.1264
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0066 0.0085
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.0983 0.1404
Mycobacterium tuberculosis Possible succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD2 0.0011 0.003 0.0034
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0092 0.0151
Echinococcus multilocularis neuropeptide receptor A26 0.0009 0.0014 0.0014
Echinococcus multilocularis Fatty aldehyde dehydrogenase 0.0011 0.003 0.003
Onchocerca volvulus 0.06 0.568 0.8155
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0012 0.0038 0.0038
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0211 0.1168
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0045 0.0146
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0011 0.0028 0.0046
Schistosoma mansoni aldehyde dehydrogenase 0.0011 0.003 0.003
Loa Loa (eye worm) abnormal catecholamine distribution protein 1 0.0382 0.3591 0.5877
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0011 0.0035 0.0058
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0105 0.0932 0.0932
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0115 0.0115
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0026 0.0178 0.0978
Loa Loa (eye worm) helicase 0.0011 0.0035 0.0058
Schistosoma mansoni smad1 5 8 and 0.0017 0.0092 0.0092
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0009 0.0014 0.0023
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0115 0.0115
Loa Loa (eye worm) D-ets-2 protein 0.001 0.0025 0.0041
Onchocerca volvulus 0.0009 0.0014 0.002
Echinococcus multilocularis ETS transcription factor Elf 1 0.001 0.0025 0.0025
Echinococcus multilocularis inositol monophosphatase 0.0008 0.0007 0.0006
Brugia malayi G protein-coupled receptor F59B2.13 0.0009 0.0014 0.0023
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0011 0.003 0.0087
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0169 0.1549 0.1549
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0093 0.0818 0.0818
Echinococcus multilocularis ewsr:fli fusion protein type 0.001 0.0025 0.0025
Mycobacterium ulcerans aldehyde dehydrogenase 0.0197 0.1814 1
Schistosoma mansoni nAChR subunit 0.0087 0.0765 0.0765
Loa Loa (eye worm) LGC-31 protein 0.0169 0.1549 0.2535
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Brugia malayi ImpB/MucB/SamB family protein 0.0043 0.0343 0.0561
Brugia malayi hypothetical protein 0.0072 0.062 0.1014
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.011 0.0983 0.3667
Echinococcus multilocularis rhodopsin orphan GPCR 0.0009 0.0014 0.0014
Schistosoma mansoni smad 0.0017 0.0092 0.0092
Loa Loa (eye worm) hypothetical protein 0.0087 0.0765 0.1252
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0011 0.003 0.0128
Loa Loa (eye worm) hypothetical protein 0.0011 0.003 0.0048
Echinococcus multilocularis bloom syndrome protein 0.0023 0.015 0.0149
Brugia malayi Cation transporter family protein 0.0169 0.1549 0.2535
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0026 0.0178 0.0178
Loa Loa (eye worm) hypothetical protein 0.0241 0.2237 0.3662
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0072 0.062 0.062
Plasmodium falciparum transporter, putative 0.0105 0.0932 0.3445
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0106 0.0372
Loa Loa (eye worm) hypothetical protein 0.0093 0.0818 0.1339
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0026 0.0178 0.095
Onchocerca volvulus 0.0009 0.0014 0.002
Brugia malayi Inositol-1 0.008 0.0696 0.1139
Schistosoma mansoni DNA polymerase eta 0.0043 0.0343 0.0343
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0211 0.0295
Loa Loa (eye worm) hypothetical protein 0.0101 0.0899 0.1471
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0115 0.0366
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0092 0.0151
Echinococcus granulosus neuropeptide FF receptor 2 0.0009 0.0014 0.0014
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0105 0.0932 0.1524
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0011 0.0035 0.0065
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0099 0.0877 0.3267
Loa Loa (eye worm) hypothetical protein 0.0042 0.0326 0.0533
Echinococcus granulosus rhodopsin orphan GPCR 0.0009 0.0014 0.0014
Trypanosoma cruzi NADH dehydrogenase, putative 0.0026 0.0178 0.0644
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0026 0.0178 0.0178
Echinococcus multilocularis musashi 0.0086 0.0754 0.0754
Echinococcus granulosus Fatty aldehyde dehydrogenase 0.0011 0.003 0.003
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0026 0.0178 0.0644
Trichomonas vaginalis apoptosis inducing factor, putative 0.0026 0.0178 0.0247
Onchocerca volvulus 0.0169 0.1549 0.2224
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0026 0.0178 0.095
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0042 0.0326 0.0325
Loa Loa (eye worm) hypothetical protein 0.0169 0.1549 0.2535
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0026 0.0178 0.0978
Echinococcus granulosus neuropeptide s receptor 0.0009 0.0014 0.0014
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0086 0.0754 0.1234
Onchocerca volvulus 0.0104 0.0928 0.1332
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0169 0.1549 0.2535
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0077 0.0662 0.0954
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0106 0.0173
Schistosoma mansoni intermediate filament proteins 0.0086 0.0754 0.0754
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0026 0.0178 0.0247
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0169 0.1549 0.1549
Echinococcus granulosus nAChR subunit 0.0169 0.1549 0.1549
Schistosoma mansoni amine GPCR 0.0009 0.0014 0.0014
Onchocerca volvulus 0.0086 0.0754 0.1083
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0009 0.0014 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0035 0.0041
Loa Loa (eye worm) hypothetical protein 0.0009 0.0009 0.0015
Trypanosoma brucei unspecified product 0.0013 0.005 0.0163
Echinococcus granulosus protein C ets 2 0.001 0.0025 0.0025
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0026 0.0178 0.0178
Mycobacterium tuberculosis Probable dehydrogenase 0.0652 0.6185 0.8984
Schistosoma mansoni neuropeptide F-like receptor 0.0009 0.0014 0.0014
Loa Loa (eye worm) ACC-1 protein 0.0169 0.1549 0.2535
Schistosoma mansoni sodium-dependent amino acid transporter 0.0105 0.0932 0.0932
Echinococcus granulosus GA binding protein alpha chain 0.0071 0.061 0.0609
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0011 0.003 0.0132
Brugia malayi 6-phosphofructokinase 0.011 0.0983 0.1609
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0169 0.1549 0.2535
Brugia malayi hypothetical protein 0.0009 0.0014 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0004
Trichomonas vaginalis glutathione reductase, putative 0.0099 0.0877 0.1251
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0105 0.0932 0.0932
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.06 0.568 0.9296
Echinococcus granulosus FTZ F1 alpha 0.0012 0.0038 0.0038
Entamoeba histolytica hypothetical protein 0.0072 0.062 0.3496
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0645 0.611 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0099 0.0877 0.3267
Echinococcus granulosus g protein coupled receptor 0.0009 0.0014 0.0014
Echinococcus multilocularis rhodopsin orphan GPCR 0.0009 0.0014 0.0014
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0211 0.2215
Leishmania major delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0011 0.003 0.0087
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0026 0.0178 0.0178
Echinococcus granulosus rhodopsin orphan GPCR 0.0009 0.0014 0.0014
Leishmania major pyrroline-5-carboxylate synthetase-like protein 0.0011 0.003 0.0087
Echinococcus granulosus Smad4 0.0017 0.0092 0.0092
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0087 0.0765 0.1252
Trichomonas vaginalis CAMK family protein kinase 0.0191 0.1761 0.2521
Schistosoma mansoni pap-inositol-14-phosphatase 0.0008 0.0007 0.0007
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.0983 0.1404
Onchocerca volvulus 0.06 0.568 0.8155
Echinococcus multilocularis RUN 0.002 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0011 0.0035 0.0058
Loa Loa (eye worm) hypothetical protein 0.0011 0.0028 0.0046
Loa Loa (eye worm) hypothetical protein 0.0169 0.1549 0.2535
Onchocerca volvulus 0.0169 0.1549 0.2224
Entamoeba histolytica phosphofructokinase, putative 0.011 0.0983 0.5567
Schistosoma mansoni neuropeptide receptor 0.0009 0.0014 0.0014
Brugia malayi hypothetical protein 0.0009 0.0014 0.0023
Schistosoma mansoni loxhd1 0.002 0.0115 0.0115
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0026 0.0178 0.0644
Loa Loa (eye worm) hypothetical protein 0.0105 0.0932 0.1524
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0834 0.119
Brugia malayi Uncoordinated protein 44 0.0015 0.0066 0.0107
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0122 0.0393
Brugia malayi hypothetical protein 0.0009 0.0014 0.0023
Echinococcus granulosus thioredoxin glutathione reductase 0.0286 0.2675 0.2675
Mycobacterium ulcerans arylsulfatase AtsB 0.0009 0.0009 0.0015
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0211 0.0295
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0092 0.0092
Loa Loa (eye worm) ATP-dependent DNA helicase 0.001 0.0018 0.0029
Schistosoma mansoni amine GPCR 0.0009 0.0014 0.0014
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0026 0.0178 0.0247
Echinococcus granulosus fmrfamide receptor 0.0009 0.0014 0.0014
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0026 0.0178 0.0978
Mycobacterium ulcerans dehydrogenase 0.0026 0.0178 0.095
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0099 0.0877 0.1434
Loa Loa (eye worm) hypothetical protein 0.0087 0.0765 0.1252
Brugia malayi nuclear hormone receptor 0.0012 0.0038 0.0062
Loa Loa (eye worm) hypothetical protein 0.0082 0.071 0.1161
Loa Loa (eye worm) hypothetical protein 0.0061 0.051 0.0835
Loa Loa (eye worm) hypothetical protein 0.0169 0.1549 0.2535
Plasmodium vivax amine transporter, putative 0.0105 0.0932 0.3402
Mycobacterium ulcerans methylmalonate semialdehyde dehydrogenase, MmsA 0.0011 0.003 0.0128
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0169 0.1549 0.2535
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0169 0.1549 0.2535
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0026 0.0178 0.0178
Brugia malayi MH1 domain containing protein 0.001 0.0018 0.0029
Schistosoma mansoni elf1 0.001 0.0025 0.0025
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0026 0.0178 0.0178
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0009 0.0014 0.0014
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0026 0.0178 0.0604
Loa Loa (eye worm) hypothetical protein 0.0008 0.0007 0.001
Echinococcus multilocularis dna polymerase eta 0.0043 0.0343 0.0343
Brugia malayi Ets-domain containing protein 0.0071 0.061 0.0997
Loa Loa (eye worm) GABA receptor subunit 0.0082 0.071 0.1161
Loa Loa (eye worm) melatonin receptor type 1A 0.0009 0.0014 0.0023
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.001 0.0025 0.0041
Echinococcus multilocularis G protein coupled receptor 139 0.0009 0.0014 0.0014
Onchocerca volvulus 0.0105 0.0932 0.1337
Echinococcus granulosus biogenic amine 5HT receptor 0.0009 0.0014 0.0014
Echinococcus granulosus sex peptide receptor 0.0009 0.0014 0.0014
Echinococcus granulosus neuropeptide receptor A26 0.0009 0.0014 0.0014
Schistosoma mansoni amine GPCR 0.0009 0.0014 0.0014
Echinococcus granulosus mixed lineage leukemia protein mll 0.0011 0.003 0.003
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0012 0.0038 0.0062
Schistosoma mansoni neuropeptide f receptor 76f 0.0009 0.0014 0.0014
Onchocerca volvulus Bile acid receptor homolog 0.0012 0.0038 0.0055
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0106 0.0372
Mycobacterium ulcerans arylsulfatase, AslA 0.0009 0.0009 0.0015
Echinococcus multilocularis g protein coupled receptor 0.0009 0.0014 0.0014
Trichomonas vaginalis myo inositol monophosphatase, putative 0.008 0.0696 0.0992
Loa Loa (eye worm) hypothetical protein 0.0169 0.1549 0.2535
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0012 0.0038 0.0062
Echinococcus granulosus glycine receptor subunit alpha 1 0.0169 0.1549 0.1549
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0012 0.0038 0.0062
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Onchocerca volvulus 0.0026 0.0178 0.0256
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0106 0.0372
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0211 0.0769
Toxoplasma gondii thioredoxin reductase 0.0286 0.267 1
Echinococcus multilocularis neuropeptides capa receptor 0.0009 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0087 0.0765 0.1252
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0211 0.0668
Mycobacterium ulcerans aldehyde dehydrogenase 0.0011 0.003 0.0128
Echinococcus granulosus neuropeptides capa receptor 0.0009 0.0014 0.0014
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0241 0.2237 0.2237
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0045 0.0146
Loa Loa (eye worm) hypothetical protein 0.0169 0.1549 0.2535
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.005 0.0163
Schistosoma mansoni 6-phosphofructokinase 0.011 0.0983 0.0983
Brugia malayi hypothetical protein 0.0123 0.111 0.1816
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0652 0.6185 0.8984
Brugia malayi Cation transporter family protein 0.06 0.568 0.9296
Brugia malayi Abnormal catecholamine distribution protein 1 0.0382 0.3591 0.5877
Brugia malayi Pre-SET motif family protein 0.0645 0.611 1
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0026 0.0178 0.1753
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0118 0.1059 0.1059
Schistosoma mansoni hypothetical protein 0.0009 0.0014 0.0014
Entamoeba histolytica disulphide oxidoreductase, putative 0.0026 0.0178 0.0978
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0105 0.0932 0.0932
Mycobacterium tuberculosis Probable aldehyde dehydrogenase (NAD+) dependent 0.0011 0.003 0.0034
Mycobacterium leprae PROBABLE ALDEHYDE DEHYDROGENASE (NAD+) DEPENDENT 0.0011 0.003 0.0034
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0169 0.1549 0.1549
Brugia malayi MH1 domain containing protein 0.001 0.0018 0.0029
Mycobacterium leprae PROBABLE SUCCINATE-SEMIALDEHYDE DEHYDROGENASE [NADP+] DEPENDENT (SSDH) GABD 0.0011 0.003 0.0034
Loa Loa (eye worm) hypothetical protein 0.001 0.0018 0.0029
Mycobacterium tuberculosis Probable methylmalonate-semialdehyde dehydrogenase MmsA (methylmalonic acid semialdehyde dehydrogenase) (MMSDH) 0.0011 0.003 0.0034
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0106 0.0142
Mycobacterium tuberculosis Probable aldehyde dehydrogenase NAD dependent AldA (aldehyde dehydrogenase [NAD+]) 0.0011 0.003 0.0034
Treponema pallidum oxidoreductase 0.0026 0.0178 0.0255
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0012 0.0038 0.0062
Echinococcus multilocularis glutamate synthase 0.0026 0.0178 0.0178
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0106 0.0372
Echinococcus granulosus voltage gated potassium channel 0.0011 0.0028 0.0028
Schistosoma mansoni hypothetical protein 0.0015 0.0066 0.0066
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0011 0.003 0.0087
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.003 0.003
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0012 0.0038 0.0038
Onchocerca volvulus 0.0101 0.0899 0.129
Trichomonas vaginalis glutamate synthase, putative 0.0026 0.0178 0.0247
Loa Loa (eye worm) steroid hormone receptor 0.0012 0.0038 0.0062
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0099 0.0877 0.4814
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0101 0.0136
Schistosoma mansoni steroid hormone receptor ad4bp 0.0012 0.0038 0.0038
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0087 0.0765 0.1252
Brugia malayi putative neuropeptide receptor NPR1 0.0009 0.0014 0.0023
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0011 0.003 0.0087
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0012 0.0038 0.0038
Echinococcus multilocularis rhodopsin orphan GPCR 0.0009 0.0014 0.0014
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0031 0.0219 0.0798
Loa Loa (eye worm) hypothetical protein 0.0012 0.0038 0.0062
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0099 0.0877 0.3267
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0099 0.0877 0.3267
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.005 0.0163
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0026 0.0178 0.025
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0046 0.037 0.0605
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, GabD1 0.0011 0.003 0.0128
Brugia malayi CHD4 protein 0.0013 0.0052 0.0085
Schistosoma mansoni sodium/chloride dependent transporter 0.0617 0.585 0.585
Loa Loa (eye worm) fli-1 protein 0.0216 0.2002 0.3276
Brugia malayi larval opioid receptor 0.0009 0.0014 0.0023
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0105 0.0932 0.0932
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0026 0.0178 0.0644
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0105 0.0932 0.0931
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.015 0.0206
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0099 0.0877 0.3267
Plasmodium vivax hypothetical protein, conserved 0.0011 0.0035 0.00000000014457
Brugia malayi MH1 domain containing protein 0.0017 0.0092 0.0151
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Brugia malayi Ets-domain containing protein 0.001 0.0025 0.0041
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Schistosoma mansoni glutamate synthase 0.0026 0.0178 0.0178
Mycobacterium tuberculosis Probable aldehyde dehydrogenase AldC 0.0011 0.003 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0004
Trichomonas vaginalis hypothetical protein 0.0011 0.0035 0.0041
Echinococcus granulosus 3'2'5' bisphosphate nucleotidase 1 0.0008 0.0007 0.0006
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0106 0.0106
Schistosoma mansoni myo inositol monophosphatase 0.0008 0.0007 0.0007
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0106 0.0372
Schistosoma mansoni voltage-gated potassium channel 0.004 0.0313 0.0313
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0099 0.0877 0.0876
Loa Loa (eye worm) glutathione reductase 0.0286 0.267 0.4369
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0725 0.6883 1
Schistosoma mansoni hypothetical protein 0.0009 0.0014 0.0014
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0106 0.0372
Schistosoma mansoni blooms syndrome DNA helicase 0.0018 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0617 0.585 0.9575
Mycobacterium ulcerans gamma-aminobutyraldehyde dehydrogenase 0.0011 0.003 0.0128
Trypanosoma cruzi DNA polymerase eta, putative 0.0031 0.0219 0.0798
Echinococcus granulosus nAChR subunit 0.0082 0.071 0.071
Brugia malayi Serotonin receptor 0.0009 0.0014 0.0023
Echinococcus granulosus ecdysone induced protein 78C 0.0012 0.0038 0.0038
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0066 0.0107
Giardia lamblia Glutamate synthase 0.0026 0.0178 0.0978
Schistosoma mansoni nAChR subunit 0.0169 0.1549 0.1549
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0009 0.0014 0.002
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0028 0.0028
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0106 0.0144
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0011 0.003 0.003
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0018 0.0029
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0092 0.0092
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0004
Schistosoma mansoni sulfide quinone reductase 0.0026 0.0178 0.0178
Echinococcus multilocularis neuropeptide FF receptor 2 0.0009 0.0014 0.0014
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0026 0.0178 0.025
Onchocerca volvulus 0.0009 0.0014 0.002
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0026 0.0178 0.0247
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0026 0.0178 0.095
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0011 0.003 0.0087
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0617 0.585 0.585
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0026 0.0178 0.1753
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0105 0.0932 0.0932
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0169 0.1549 0.2535
Mycobacterium leprae conserved hypothetical protein 0.002 0.0119 0.0164
Schistosoma mansoni aldehyde dehydrogenase 0.0011 0.003 0.003
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0105 0.0932 0.3473
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0191 0.1761 0.1761
Trichomonas vaginalis glutamate synthase, putative 0.0026 0.0178 0.0247
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0011 0.003 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0035 0.0041
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0026 0.0178 0.0247
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0075 0.0642 0.0642
Brugia malayi neuropeptide F receptor 0.0009 0.0014 0.0023
Loa Loa (eye worm) hypothetical protein 0.004 0.031 0.0508
Echinococcus granulosus tachykinin peptides receptor 99D 0.0009 0.0014 0.0014
Schistosoma mansoni neurotransmitter gated ion channel 0.0087 0.0765 0.0765
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0087 0.0765 0.1252
Echinococcus multilocularis sex peptide receptor 0.0009 0.0014 0.0014
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, PutA_2 0.0011 0.003 0.0128
Trichomonas vaginalis CAMK family protein kinase 0.0191 0.1761 0.2521
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0009 0.0014 0.0014
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0066 0.0094
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0066 0.0065
Echinococcus multilocularis chromobox protein 1 0.0011 0.0035 0.0035
Mycobacterium ulcerans gamma-glutamyl phosphate reductase 0.0011 0.003 0.0128
Onchocerca volvulus 0.0012 0.0038 0.0055
Brugia malayi Smad1 0.0017 0.0092 0.0151
Echinococcus multilocularis ets variant gene 4 0.001 0.0025 0.0025
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.003 0.003
Plasmodium falciparum ferrodoxin reductase-like protein 0.0026 0.0178 0.0604
Entamoeba histolytica phosphofructokinase, putative 0.011 0.0983 0.5567
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0104 0.0928 0.0928
Loa Loa (eye worm) hypothetical protein 0.001 0.0018 0.0029
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0009 0.0014 0.0014
Entamoeba histolytica thioredoxin reductase, putative 0.0026 0.0178 0.0978
Loa Loa (eye worm) hypothetical protein 0.0082 0.071 0.1161
Loa Loa (eye worm) hypothetical protein 0.0105 0.0932 0.1524
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0106 0.0372
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.008 0.0696 0.259
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0009 0.0014 0.0014
Schistosoma mansoni hypothetical protein 0.105 1 1
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.011 0.0983 0.142
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0026 0.0178 0.0247
Echinococcus multilocularis aldehyde dehydrogenase family 3 member B1 0.0011 0.003 0.003
Schistosoma mansoni neuropeptide receptor 0.0009 0.0014 0.0014
Brugia malayi hypothetical protein 0.0009 0.0014 0.0023
Schistosoma mansoni lamin 0.0086 0.0754 0.0754
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0018 0.0044
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0009 0.0014 0.0014
Echinococcus granulosus ETS transcription factor Elf 2 0.001 0.0025 0.0025
Echinococcus granulosus neuropeptides capa receptor 0.0009 0.0014 0.0014
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0011 0.003 0.0087
Onchocerca volvulus Neuropeptide F receptor homolog 0.0009 0.0014 0.002
Schistosoma mansoni nAChR subunit 0.0169 0.1549 0.1549
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0169 0.1549 0.2535
Trypanosoma brucei NADH dehydrogenase 0.0026 0.0178 0.0644
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0026 0.0178 0.0644
Echinococcus multilocularis ETS transcription factor Elf 2 0.001 0.0025 0.0025
Brugia malayi DNA-binding protein D-ETS-3 0.001 0.0025 0.0041
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0012 0.0038 0.0038
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0011 0.0028 0.0028
Plasmodium vivax thioredoxin reductase, putative 0.0286 0.267 1
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 0.0011 0.003 0.0034
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0099 0.0877 0.4814
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0011 0.003 0.0034
Brugia malayi F/Y-rich N-terminus family protein 0.0013 0.0047 0.0077
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0042 0.0326 0.0325
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0012 0.0038 0.0038
Brugia malayi Pre-SET motif family protein 0.0093 0.0818 0.1339
Schistosoma mansoni DNA helicase recq5 0.001 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0011 0.003 0.0087
Echinococcus multilocularis Chromobox protein 3 0.0011 0.0035 0.0035
Loa Loa (eye worm) RecQ helicase 0.0023 0.015 0.0244
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0004
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0038 0.0062
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0101 0.0136
Trypanosoma cruzi polo-like protein kinase, putative 0.0191 0.1761 0.6587
Echinococcus granulosus dna polymerase eta 0.0043 0.0343 0.0343
Schistosoma mansoni amine GPCR 0.0009 0.0014 0.0014
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0077 0.0662 0.238
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0105 0.0932 0.0932
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0038 0.0062
Leishmania major trypanothione reductase 0.0286 0.267 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0099 0.0877 0.3267
Loa Loa (eye worm) hypothetical protein 0.0015 0.0066 0.0107
Echinococcus multilocularis inositol monophosphatase 1 0.008 0.0696 0.0696
Echinococcus multilocularis betaine aldehyde dehydrogenase 0.0011 0.003 0.003
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0169 0.1549 0.1549
Loa Loa (eye worm) hypothetical protein 0.0087 0.0765 0.1252
Loa Loa (eye worm) hypothetical protein 0.0015 0.0067 0.0109
Echinococcus granulosus biogenic amine 5HT receptor 0.0009 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0082 0.071 0.1161
Echinococcus multilocularis smad 0.0017 0.0092 0.0092
Echinococcus multilocularis sodium and chloride dependent glycine 0.0105 0.0932 0.0931
Loa Loa (eye worm) hypothetical protein 0.0617 0.585 0.9575
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0099 0.0877 0.3267
Brugia malayi 6-phosphofructokinase 0.011 0.0983 0.1609
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0004
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0012 0.0038 0.0038
Onchocerca volvulus 0.0617 0.585 0.84
Brugia malayi transcription factor E74 isoform 0.001 0.0025 0.0041
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0066 0.0065
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0082 0.071 0.071
Echinococcus granulosus Chromobox protein 3 0.0011 0.0035 0.0035
Schistosoma mansoni histamine h1 receptor 0.0009 0.0014 0.0014
Schistosoma mansoni acetylcholine receptor subunit beta 0.0087 0.0765 0.0765
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0169 0.1549 0.2535
Trichomonas vaginalis set domain proteins, putative 0.0733 0.6964 1
Onchocerca volvulus Putative nachr subunit 0.0241 0.2237 0.3212
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0106 0.0173
Echinococcus multilocularis microtubule associated protein 2 0.0801 0.761 0.761
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.002 0.0119 0.0625
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0011 0.003 0.0128
Loa Loa (eye worm) hypothetical protein 0.0012 0.0038 0.0062
Entamoeba histolytica hypothetical protein 0.0082 0.071 0.4009
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0099 0.0877 0.3267
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.008 0.0696 0.259
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0009 0.0014 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0035 0.0041
Loa Loa (eye worm) hypothetical protein 0.002 0.0115 0.0188
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.001 0.0025 0.0041
Echinococcus granulosus microtubule associated protein 2 0.0801 0.761 0.761
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0038 0.0062
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0012 0.0038 0.0062
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0169 0.1549 0.1549
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0066 0.0065
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0241 0.2237 0.2237
Schistosoma mansoni opsin-like receptor 0.0009 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0169 0.1549 0.2535
Schistosoma mansoni hypothetical protein 0.105 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0035 0.0041
Schistosoma mansoni hypothetical protein 0.0008 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0075 0.0258
Mycobacterium ulcerans aldehyde dehydrogenase 0.0197 0.1814 1
Schistosoma mansoni aldehyde dehydrogenase 0.0011 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0011 0.0035 0.0058
Echinococcus granulosus tm gpcr rhodopsin 0.0009 0.0014 0.0014
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0066 0.0066
Echinococcus granulosus hypothetical protein 0.0009 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0087 0.0765 0.1252
Toxoplasma gondii gamma-glutamyl phosphate reductase, putative 0.0011 0.003 0.0087
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0026 0.0178 0.095
Echinococcus granulosus inositol monophosphatase 0.0008 0.0007 0.0006
Brugia malayi hypothetical protein 0.0087 0.0765 0.1252
Brugia malayi hypothetical protein 0.0087 0.0765 0.1252
Schistosoma mansoni hypothetical protein 0.0009 0.0014 0.0014
Echinococcus multilocularis ETS transcription factor Elf 2 0.001 0.0025 0.0025
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0008 0.0007 0.001
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0725 0.6883 1
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0011 0.0035 0.0035
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0169 0.1549 0.2535
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Echinococcus granulosus G protein coupled receptor 139 0.0009 0.0014 0.0014
Plasmodium vivax SET domain protein, putative 0.0093 0.0818 0.2972
Loa Loa (eye worm) hypothetical protein 0.0011 0.0035 0.0058
Trichomonas vaginalis CAMK family protein kinase 0.0191 0.1761 0.2521
Brugia malayi Valyl-tRNA synthetase 0.0011 0.0035 0.0058
Echinococcus multilocularis 3'(2'),5' bisphosphate nucleotidase 1 0.0008 0.0007 0.0006
Loa Loa (eye worm) 6-phosphofructokinase 0.011 0.0983 0.1609
Brugia malayi hypothetical protein 0.0009 0.0014 0.0023
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0099 0.0877 0.3267
Schistosoma mansoni chromobox protein 0.0011 0.0035 0.0035
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0093 0.0818 0.0818
Onchocerca volvulus Inositol monophosphatase 3 homolog 0.0008 0.0007 0.0009
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0012 0.0038 0.0038
Echinococcus granulosus peptide allatostatin:somatostatin 0.0009 0.0014 0.0014
Brugia malayi Intermediate filament tail domain containing protein 0.0086 0.0754 0.1234
Brugia malayi hypothetical protein 0.0009 0.0014 0.0023
Loa Loa (eye worm) solute carrier family 6 member 4 0.0617 0.585 0.9575
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0026 0.0178 0.0247
Brugia malayi Dopamine receptor protein 2 0.0009 0.0014 0.0023
Onchocerca volvulus 0.0082 0.071 0.1019
Schistosoma mansoni neuropeptide receptor 0.0009 0.0014 0.0014
Leishmania major ATP-dependent phosphofructokinase 0.011 0.0983 0.3667
Schistosoma mansoni aldehyde dehydrogenase 0.0011 0.003 0.003
Brugia malayi hypothetical protein 0.0087 0.0765 0.1252
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0099 0.0877 0.3238
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0012 0.0038 0.0038
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0099 0.0877 0.3267
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0009 0.0014 0.0014
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0106 0.0372
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0105 0.0932 0.1524
Brugia malayi Inositol monophosphatase family protein 0.0008 0.0007 0.001
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0169 0.1549 0.2535
Trypanosoma cruzi NADH dehydrogenase, putative 0.0026 0.0178 0.0644
Loa Loa (eye worm) neuropeptide F receptor 0.0009 0.0014 0.0023
Loa Loa (eye worm) hypothetical protein 0.0169 0.1549 0.2535
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0026 0.0178 0.0178
Brugia malayi Cation transporter family protein 0.0169 0.1549 0.2535
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0211 0.0769
Entamoeba histolytica hypothetical protein 0.0011 0.0035 0.0164
Loa Loa (eye worm) hypothetical protein 0.0011 0.0035 0.0058
Echinococcus granulosus lamin 0.0086 0.0754 0.0754
Trypanosoma brucei delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0011 0.003 0.0087
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0009 0.0014 0.0014
Schistosoma mansoni growth hormone secretagogue receptor 0.0009 0.0014 0.0014
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0077 0.0662 0.1084
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0035 0.0164
Echinococcus granulosus allatostatin A receptor 0.0009 0.0014 0.0014
Brugia malayi GnHR receptor homolog 0.0009 0.0014 0.0023
Onchocerca volvulus 0.002 0.0115 0.0165
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0071 0.0092
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0012 0.0038 0.0062
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0011 0.003 0.0128
Brugia malayi RE15519p 0.0009 0.0014 0.0023
Onchocerca volvulus 0.0009 0.0014 0.002
Loa Loa (eye worm) hypothetical protein 0.0026 0.0178 0.0291
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0211 0.0312
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0026 0.0178 0.0291
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0071 0.061 0.0997
Brugia malayi ecdysteroid receptor 0.0012 0.0038 0.0062
Mycobacterium ulcerans bifunctional acetaldehyde-CoA/alcohol dehydrogenase 0.0011 0.003 0.0128
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0077 0.0662 0.2429
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0009 0.0014 0.0023
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0035 0.0041
Echinococcus granulosus tm gpcr rhodopsin 0.0009 0.0014 0.0014
Echinococcus multilocularis chromobox protein 1 0.0011 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0099 0.0877 0.3267
Schistosoma mansoni RAR-like nuclear receptor 0.0012 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.06 0.568 0.9296
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0026 0.0178 0.0178
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0038 0.0038
Onchocerca volvulus 0.0009 0.0014 0.002
Echinococcus multilocularis orexin receptor type 2 0.0009 0.0014 0.0014
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0105 0.0932 0.0932
Echinococcus multilocularis serotonin receptor 0.0009 0.0014 0.0014
Echinococcus multilocularis protein C ets 2 0.001 0.0025 0.0025
Brugia malayi Inositol monophosphatase family protein 0.0008 0.0007 0.001
Schistosoma mansoni glutamate synthase 0.0026 0.0178 0.0178
Loa Loa (eye worm) hypothetical protein 0.0105 0.0932 0.1524
Loa Loa (eye worm) hypothetical protein 0.0087 0.0765 0.1252
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0035 0.0041
Echinococcus granulosus nuclear factor of activated T cells 5 0.0075 0.0642 0.0642
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.001 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0169 0.1549 0.2535
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0012 0.0038 0.0038
Echinococcus granulosus bloom syndrome protein 0.0023 0.015 0.0149
Leishmania major DNA polymerase eta, putative 0.0031 0.0219 0.0798
Loa Loa (eye worm) aldehyde dehydrogenase 4 0.0011 0.003 0.0048
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0009 0.0014 0.0014
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.008 0.0696 0.3817
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0099 0.0877 0.3238
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0197 0.1814 0.1814
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0106 0.0565
Onchocerca volvulus 0.0086 0.0754 0.1083
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.002 0.0119 0.0195
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0016 0.0077 0.0158
Loa Loa (eye worm) heterochromatin protein 1 0.0011 0.0035 0.0058
Schistosoma mansoni alpha-1 adrenergic receptor 0.0009 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0012 0.0038 0.0062
Schistosoma mansoni coup transcription factor 0.0012 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0087 0.0765 0.1252
Brugia malayi Sulfatase family protein 0.0009 0.0009 0.0015
Plasmodium vivax ferrodoxin reductase, putative 0.0026 0.0178 0.0542
Echinococcus multilocularis rhodopsin orphan GPCR 0.0009 0.0014 0.0014
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0169 0.1549 0.1549
Brugia malayi Aldehyde dehydrogenase protein 4 0.0011 0.003 0.0048
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0009 0.0014 0.0014
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0211 0.0295
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0009 0.0014 0.0014
Onchocerca volvulus 0.0009 0.0014 0.002
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0009 0.0014 0.0023
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0169 0.1549 0.2535
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0087 0.0765 0.1252
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0087 0.0765 0.1252
Echinococcus multilocularis neuropeptide s receptor 0.0009 0.0014 0.0014
Onchocerca volvulus 0.0087 0.0765 0.1098
Echinococcus granulosus somatostatin receptor 0.0009 0.0014 0.0014
Trichomonas vaginalis succinate semialdehyde dehydrogenase, putative 0.0011 0.003 0.0033
Entamoeba histolytica serine/threonine protein kinase, putative 0.0191 0.1761 1
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0082 0.071 0.1161
Loa Loa (eye worm) hypothetical protein 0.0086 0.0754 0.1234
Echinococcus granulosus ETS domain containing protein Elk 1 0.001 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Echinococcus multilocularis lamin 0.0086 0.0754 0.0754
Onchocerca volvulus 0.0082 0.071 0.1019
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0009 0.0014 0.0014
Echinococcus multilocularis neuropeptide receptor 0.0009 0.0014 0.0014
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.001 0.0018 0.0018
Schistosoma mansoni Smad4 0.0017 0.0092 0.0092
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0105 0.0932 0.1524
Loa Loa (eye worm) hypothetical protein 0.0087 0.0765 0.1252
Brugia malayi hypothetical protein 0.0009 0.0009 0.0015
Echinococcus granulosus neuropeptide Y receptor 0.0009 0.0014 0.0014
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0099 0.0877 1
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0099 0.0877 1
Brugia malayi Ets-domain containing protein 0.0071 0.061 0.0997
Loa Loa (eye worm) delta-1-pyrroline-5-carboxylate dehydrogenase 0.0011 0.003 0.0048
Loa Loa (eye worm) hypothetical protein 0.0105 0.0932 0.1524
Loa Loa (eye worm) hypothetical protein 0.0012 0.0038 0.0062
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0101 0.0136
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0026 0.0178 0.025
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0241 0.2237 0.2237
Echinococcus granulosus Ankyrin repeat domain containing protein 0.009 0.0789 0.0789
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0026 0.0178 0.025
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0087 0.0765 0.0765
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0009 0.0014 0.0014
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0169 0.1549 0.2535
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0169 0.1549 0.1549
Schistosoma mansoni inositol monophosphatase 0.008 0.0696 0.0696
Brugia malayi follicle stimulating hormone receptor 0.0242 0.2252 0.3685
Leishmania major hypothetical protein, conserved 0.0026 0.0178 0.0644
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0105 0.0932 0.0931
Mycobacterium ulcerans epimerase 0.002 0.0119 0.0625
Giardia lamblia Hypothetical protein 0.0009 0.0009 0.0016
Brugia malayi photoreceptor-specific nuclear receptor 0.0012 0.0038 0.0062
Onchocerca volvulus 0.0009 0.0014 0.002
Echinococcus granulosus histone lysine methyltransferase setb 0.0093 0.0818 0.0818
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0101 0.0136
Onchocerca volvulus 0.0009 0.0014 0.002
Loa Loa (eye worm) inositol-1 0.008 0.0696 0.1139
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0106 0.0372
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0241 0.2237 0.3662
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0106 0.0372
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0652 0.6185 0.8984
Schistosoma mansoni delta 1-pyrroline-5-carboxylate synthetase 0.0011 0.003 0.003
Schistosoma mansoni rab6-interacting 0.002 0.0115 0.0115
Leishmania major DNA polymerase kappa, putative 0.0019 0.0106 0.0372
Brugia malayi Death domain containing protein 0.0015 0.0066 0.0107
Leishmania major aldehyde dehydrogenase, putative 0.0011 0.003 0.0087
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0169 0.1549 0.1549
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0169 0.1549 0.2535
Loa Loa (eye worm) hypothetical protein 0.0169 0.1549 0.2535
Leishmania major hypothetical protein, conserved 0.0026 0.0178 0.0644
Loa Loa (eye worm) hypothetical protein 0.0087 0.0765 0.1252
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0242 0.2252 0.3685
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.0352 0.0576
Echinococcus granulosus glycine receptor subunit beta 0.0169 0.1549 0.1549
Trypanosoma brucei hypothetical protein, conserved 0.0026 0.0178 0.0644
Loa Loa (eye worm) hypothetical protein 0.0087 0.0765 0.1252
Echinococcus multilocularis Ankyrin 0.0015 0.0067 0.0067
Schistosoma mansoni succinate semialdehyde dehydrogenase 0.0011 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0037 0.028 0.0458
Onchocerca volvulus 0.0009 0.0014 0.002
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.009 0.0789 0.0789
Treponema pallidum sodium- and chloride- dependent transporter 0.0617 0.585 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0009 0.0014 0.0014
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0012 0.0038 0.0062
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0082 0.071 0.1161
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0105 0.0932 0.0931
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0352 0.0352
Brugia malayi Melatonin receptor type 1A 0.0009 0.0014 0.0023
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0026 0.0178 0.0644
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0099 0.0877 0.3267
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0009 0.0014 0.0014
Onchocerca volvulus 0.0169 0.1549 0.2224
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.001 0.0025 0.0025
Mycobacterium ulcerans arylsulfatase AtsD 0.0009 0.0009 0.0015
Plasmodium falciparum heterochromatin protein 1 0.0011 0.0035 0.0065
Schistosoma mansoni 6-phosphofructokinase 0.011 0.0983 0.0983
Plasmodium vivax hypothetical protein, conserved 0.0105 0.0932 0.3402
Echinococcus granulosus ETS transcription factor Elf 5 0.001 0.0025 0.0025
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0211 0.1168
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0011 0.0035 0.0108
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0652 0.6185 0.8984
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0026 0.0178 0.0604
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0026 0.0178 0.0978
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0087 0.0765 0.1252
Mycobacterium ulcerans hypothetical protein 0.002 0.0119 0.0625
Echinococcus multilocularis FTZ F1 alpha 0.0012 0.0038 0.0038
Echinococcus multilocularis thyroid hormone receptor alpha 0.0012 0.0038 0.0038
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.0983 0.1404
Mycobacterium ulcerans 6-phosphofructokinase 0.011 0.0983 0.5403
Loa Loa (eye worm) hypothetical protein 0.0082 0.071 0.1161
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0099 0.0877 0.9407
Loa Loa (eye worm) Smad1 0.0017 0.0092 0.0151
Echinococcus granulosus death domain containing protein 0.0015 0.0066 0.0065
Mycobacterium ulcerans ferredoxin reductase 0.0026 0.0178 0.095
Entamoeba histolytica hypothetical protein 0.0072 0.062 0.3496
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Trichomonas vaginalis Heterochromatin protein, putative 0.0011 0.0035 0.0041
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0191 0.1761 0.2881
Echinococcus granulosus rhodopsin orphan GPCR 0.0009 0.0014 0.0014
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0035 0.0041
Echinococcus multilocularis ecdysone induced protein 78C 0.0012 0.0038 0.0038
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0038 0.0062
Echinococcus granulosus ETS transcription factor Elf 1 0.001 0.0025 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0035 0.0041
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0026 0.0178 0.0247
Entamoeba histolytica aldehyde-alcohol dehydrogenase 2, putative 0.0011 0.003 0.0132
Trypanosoma cruzi polo-like protein kinase, putative 0.0191 0.1761 0.6587
Loa Loa (eye worm) hypothetical protein 0.0012 0.0038 0.0062
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0087 0.0765 0.1252
Trypanosoma cruzi trypanothione reductase, putative 0.0286 0.267 1
Schistosoma mansoni cpg binding protein 0.003 0.0216 0.0216
Echinococcus multilocularis somatostatin receptor 0.0009 0.0014 0.0014
Schistosoma mansoni sulfide quinone reductase 0.0026 0.0178 0.0178
Echinococcus granulosus smad 0.0017 0.0092 0.0092
Onchocerca volvulus 0.0101 0.0899 0.129
Schistosoma mansoni myosin xvIII 0.0009 0.0014 0.0014
Toxoplasma gondii NADP-dependent succinate-semialdehyde dehydrogenase 0.0011 0.003 0.0087
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0093 0.0818 0.0818
Schistosoma mansoni smad1 5 8 and 0.0017 0.0092 0.0092
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0105 0.0932 0.0931
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0286 0.267 0.3873
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0106 0.0372
Toxoplasma gondii hypothetical protein 0.0105 0.0932 0.3473
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.0257 0.036
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0012 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0169 0.1549 0.2535
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0026 0.0178 0.0644
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0009 0.0014 0.0014
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0026 0.0178 0.0247
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0169 0.1549 0.1549
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0101 0.0136
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0106 0.0372
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0011 0.003 0.0087
Brugia malayi phosphofructokinase 0.011 0.0983 0.1609
Brugia malayi serine/threonine-protein kinase plk-2 0.0191 0.1761 0.2881
Echinococcus multilocularis serotonin transporter 0.0617 0.585 0.585
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0106 0.0372
Echinococcus granulosus betaine aldehyde dehydrogenase 0.0011 0.003 0.003
Schistosoma mansoni ets-related 0.0216 0.2002 0.2002
Brugia malayi chromobox protein homolog 3 0.0011 0.0035 0.0058
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0009 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0617 0.585 0.9575
Loa Loa (eye worm) hypothetical protein 0.0009 0.0014 0.0023
Onchocerca volvulus Aldehyde dehydrogenase homolog 0.0011 0.003 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0004
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0011 0.003 0.0087
Mycobacterium ulcerans NADH dehydrogenase 0.0026 0.0178 0.095
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0011 0.003 0.0087
Onchocerca volvulus 0.0087 0.0765 0.1098
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0009 0.0014 0.0014
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0725 0.6883 1
Giardia lamblia Alcohol dehydrogenase 0.0011 0.003 0.0132
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0009 0.0004
Brugia malayi hypothetical protein 0.0087 0.0765 0.1252
Schistosoma mansoni opsin-like receptor 0.0009 0.0014 0.0014
Echinococcus granulosus dro:myosuppressin receptor 0.0009 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0012 0.0038 0.0062
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0012 0.0038 0.0062
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.002 0.0119 0.0171
Entamoeba histolytica hypothetical protein 0.0072 0.062 0.3496
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.008 0.0696 0.259
Schistosoma mansoni microtubule-associated protein tau 0.0801 0.761 0.761
Brugia malayi sulfakinin receptor protein 0.0009 0.0014 0.0023
Schistosoma mansoni lipoxygenase 0.0118 0.1059 0.1059
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0038 0.0038
Chlamydia trachomatis thioredoxin reductase 0.0026 0.0178 0.1856
Loa Loa (eye worm) hypothetical protein 0.0102 0.09 0.1473

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) Anticonvulsant activity determined at 4 hours after the administration of compound using sc Ptz test. (- denotes activity at 300 mg/kg) ChEMBL. 9719582
Activity (functional) Anticonvulsant activity determined at 30 minutes after the administration of compound using sc Ptz test. (+++ = activity at 30 mg/kg) ChEMBL. 9719582
Activity (functional) Anticonvulsant activity determined at 4 hours after the administration of compound using MES test.(++= signify activity at 100 mg/kg) ChEMBL. 9719582
Activity (functional) Anticonvulsant activity determined at 30 minutes after the administration of compound using MES test. (+++ = activity at 30 mg/kg) ChEMBL. 9719582
Activity (functional) 0 Anticonvulsant activity determined at 30 minutes after the administration of compound using MES test. (+++ = activity at 30 mg/kg) ChEMBL. 9719582
Activity (functional) 0 Anticonvulsant activity determined at 4 hours after the administration of compound using MES test.(++= signify activity at 100 mg/kg) ChEMBL. 9719582
Activity (functional) 0 Anticonvulsant activity determined at 30 minutes after the administration of compound using sc Ptz test. (+++ = activity at 30 mg/kg) ChEMBL. 9719582
Activity (functional) 0 Anticonvulsant activity determined at 4 hours after the administration of compound using sc Ptz test. (- denotes activity at 300 mg/kg) ChEMBL. 9719582
Activity (ADMET) 0 Neurotoxicity determined at 30 minutes after the administration of compound by rotorod test.(++= signify activity at 100 mg/kg) ChEMBL. 9719582
Activity (ADMET) 0 Neurotoxicity determined at 4 hours after the administration of compound by rotorod test (++= signify activity at 100 mg/kg) ChEMBL. 9719582
Activity (functional) 0 Anticonvulsant activity was determined in rats at a dose of 30 mg/kg after 15 minutes by MES test. (++++ denotes activity in 75-100% of administered animals) ChEMBL. 9719582
Activity (functional) 0 Anticonvulsant activity was determined in rats at a dose of 30 mg/kg after 30 minutes by MES test. (++++ denotes activity in 75-100% of administered animals) ChEMBL. 9719582
Activity (functional) 0 Anticonvulsant activity was determined in rats at a dose of 30 mg/kg after 1 hour by MES test. (++++ denotes activity in 75-100% of administered animals) ChEMBL. 9719582
Activity (functional) 0 Anticonvulsant activity was determined in rats at a dose of 30 mg/kg after 2 hour by MES test. (++++ denotes activity in 75-100% of administered animals) ChEMBL. 9719582
Activity (functional) 0 Anticonvulsant activity was determined in rats at a dose of 30 mg/kg after 4 hour by MES test. (++ denotes activity in 25-50% of administered animals). ChEMBL. 9719582
Activity (functional) 0 Toxicity was determined in rats at a dose of 30 mg/kg after 4 hour .(- denotes no activity in administered animals). ChEMBL. 9719582
ED50 (functional) = 6.7 uM Effective dose administered intraperitoneally in the MES model ChEMBL. 11170622
ED50 (functional) = 25.3 uM kg-1 Anticonvulsant ED50 activity by MES test in rats dosed orally ChEMBL. 9719582
IC50 (binding) = 15 ug ml-1 Inhibitory activity against aminopeptidase N (APN) in human acute lymphoblastic leukemia MOLT-4 cell line ChEMBL. 10098663
IC50 (binding) = 15 ug ml-1 Inhibitory activity of the compound against aminopeptidase N assayed by the L-Ala-MCA method. ChEMBL. 9464355
IC50 (binding) = 15 ug ml-1 Inhibitory activity against aminopeptidase N (APN) in human acute lymphoblastic leukemia MOLT-4 cell line ChEMBL. 10098663
IC50 (binding) = 15 ug ml-1 Inhibitory activity of the compound against aminopeptidase N assayed by the L-Ala-MCA method. ChEMBL. 9464355
IC50 (binding) = 23.4 ug ml-1 Inhibitory activity against Dipeptidyl-peptidase IV (DPP IV) in human acute lymphoblastic leukemia MOLT-4 cell line ChEMBL. 10098663
IC50 (binding) = 23.4 ug ml-1 Inhibitory activity of the compound against dipeptidyl peptidase IV (DPP- IV) ChEMBL. 9464355
IC50 (binding) = 23.4 ug ml-1 Inhibitory activity against Dipeptidyl-peptidase IV (DPP IV) in human acute lymphoblastic leukemia MOLT-4 cell line ChEMBL. 10098663
IC50 (binding) = 23.4 ug ml-1 Inhibitory activity of the compound against dipeptidyl peptidase IV (DPP- IV) ChEMBL. 9464355
IC50 (functional) > 100 ug ml-1 Cytotoxicity in human embryonic lung flbroblast Wl-38 cells using WST-1 viability assay ChEMBL. 10098663
IC50 (binding) = 0.11 uM Apparent IC50 value by [3H]-batrachotoxinin-A-20-alpha-benzoate-binding test performed in rat brain synaptosomes ChEMBL. 9719582
IC50 (binding) = 0.11 uM Inhibition of [3H]-BTX binding to cardiac voltage-gated sodium channel ChEMBL. 11170622
IC50 (binding) = 56.3 uM Inhibitory activity against aminopeptidase N (APN) in human acute lymphoblastic leukemia MOLT-4 cell line ChEMBL. 10098663
IC50 (binding) = 56.3 uM Inhibitory activity against aminopeptidase N (APN) in human acute lymphoblastic leukemia MOLT-4 cell line ChEMBL. 10098663
IC50 (binding) = 87.9 uM Inhibitory activity against Dipeptidyl-peptidase IV (DPP IV) in human acute lymphoblastic leukemia MOLT-4 cell line ChEMBL. 10098663
IC50 (binding) = 87.9 uM Inhibitory activity against Dipeptidyl-peptidase IV (DPP IV) in human acute lymphoblastic leukemia MOLT-4 cell line ChEMBL. 10098663
IC50 (functional) > 375.5 uM Cytotoxicity in human embryonic lung flbroblast Wl-38 cells using WST-1 viability assay ChEMBL. 10098663

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

4 literature references were collected for this gene.

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