Detailed information for compound 410043

Basic information

Technical information
  • TDR Targets ID: 410043
  • Name: 3-fluoro-N-(4-hydroxybutyl)-4-[4-(trifluorome thyl)phenyl]benzenesulfonamide
  • MW: 391.38 | Formula: C17H17F4NO3S
  • H donors: 2 H acceptors: 3 LogP: 3.53 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCCCCNS(=O)(=O)c1ccc(c(c1)F)c1ccc(cc1)C(F)(F)F
  • InChi: 1S/C17H17F4NO3S/c18-16-11-14(26(24,25)22-9-1-2-10-23)7-8-15(16)12-3-5-13(6-4-12)17(19,20)21/h3-8,11,22-23H,1-2,9-10H2
  • InChiKey: BVDPNJVNZDGPIG-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica protein kinase domain containing protein 0.0144 0.1108 0.2876
Onchocerca volvulus 0.005 0.012 0.0304
Onchocerca volvulus Netrin receptor homolog 0.0042 0.0039 0.0097
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.037 0.3473 0.8916
Loa Loa (eye worm) hypothetical protein 0.0411 0.3895 0.3894
Trichomonas vaginalis CAMK family protein kinase 0.0283 0.2562 0.7411
Entamoeba histolytica protein kinase, putative 0.0049 0.0109 0.0242
Schistosoma mansoni hypothetical protein 0.0118 0.0837 0.1726
Echinococcus granulosus protein kinase c eta type 0.0044 0.0063 0.0108
Trichomonas vaginalis STE family protein kinase 0.0051 0.013 0.0244
Loa Loa (eye worm) hypothetical protein 0.0062 0.0253 0.0252
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0087 0.0506 0.1824
Echinococcus multilocularis casein kinase I alpha 0.0112 0.0772 0.1517
Schistosoma mansoni tyrosine kinase 0.0164 0.1319 0.272
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0559 0.1507
Entamoeba histolytica hypothetical protein 0.0043 0.0047 0.0079
Loa Loa (eye worm) hypothetical protein 0.0177 0.145 0.1449
Entamoeba histolytica cell division protein kinase 2, putative 0.0123 0.0884 0.2287
Trypanosoma brucei casein kinase I, isoform 2 0.0112 0.0772 0.2136
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0103 0.0677 0.3687
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0271 0.2435 0.4821
Loa Loa (eye worm) hypothetical protein 0.0177 0.145 0.1449
Loa Loa (eye worm) hypothetical protein 0.0082 0.0453 0.0452
Echinococcus multilocularis dual specificity 0.0144 0.1108 0.2184
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0164 0.1319 0.2604
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0092 0.0559 0.2033
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0177 0.145 0.2863
Entamoeba histolytica PH domain containing protein kinase, putative 0.0128 0.0934 0.2418
Echinococcus granulosus casein kinase I alpha 0.0112 0.0772 0.1517
Echinococcus multilocularis Immunoglobulin 0.0051 0.0135 0.0252
Giardia lamblia Kinase, NEK 0.0141 0.1076 0.3891
Echinococcus multilocularis RNA directed DNA polymerase 0.0042 0.0039 0.0061
Schistosoma mansoni serine/threonine protein kinase 0.0055 0.0174 0.0358
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0133 0.0994 0.0993
Loa Loa (eye worm) CAMK protein kinase 0.0046 0.0079 0.0078
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0177 0.145 0.2863
Echinococcus multilocularis serine:threonine protein kinase 0.0118 0.0832 0.1637
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.016 0.127 0.4863
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0117 0.082 0.3074
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0559 0.1507
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0177 0.145 0.1449
Echinococcus multilocularis twitchin 0.0043 0.0053 0.0089
Brugia malayi protein kinase C3,putative 0.0164 0.1315 0.1314
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0177 0.145 0.1449
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0072 0.0357 0.0692
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0151 0.118 0.3066
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0118 0.0832 0.0831
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0174 0.1422 0.2807
Schistosoma mansoni nAChR subunit 0.0177 0.145 0.2988
Loa Loa (eye worm) hypothetical protein 0.0118 0.0837 0.0836
Trypanosoma brucei Casein kinase II 0.0103 0.0677 0.1857
Toxoplasma gondii NEK kinase 0.0051 0.013 0.0253
Trypanosoma cruzi casein kinase II, putative 0.0103 0.0677 0.2505
Loa Loa (eye worm) hypothetical protein 0.0095 0.0596 0.0595
Brugia malayi ephrin receptor 1 precursor 0.005 0.0119 0.0118
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0123 0.0884 0.0883
Echinococcus granulosus c src tyrosine kinase 0.0041 0.0032 0.0048
Plasmodium vivax serine/threonine-protein kinase NEK4, putative 0.0051 0.013 0.0485
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0677 0.1857
Brugia malayi diacylglycerol kinase 0.0044 0.0063 0.0062
Mycobacterium ulcerans hypothetical protein 0.0108 0.0725 0.5
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0117 0.082 0.4524
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0177 0.145 0.2863
Entamoeba histolytica PH domain containing protein kinase, putative 0.0217 0.187 0.4885
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0072 0.0357 0.0692
Entamoeba histolytica protein kinase 2, putative 0.0206 0.1756 0.4585
Schistosoma mansoni protein kinase 0.0088 0.0521 0.1074
Loa Loa (eye worm) hypothetical protein 0.0082 0.0453 0.0452
Echinococcus multilocularis mitogen activated protein kinase 14 0.0165 0.1331 0.2627
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.015 0.1172 0.2312
Onchocerca volvulus 0.0147 0.1136 0.2916
Loa Loa (eye worm) hypothetical protein 0.0046 0.0077 0.0076
Echinococcus multilocularis unc 13 (munc13) 0.0046 0.0077 0.0136
Schistosoma mansoni protein kinase 0.0112 0.0772 0.1591
Brugia malayi Protein kinase domain containing protein 0.0171 0.1386 0.1385
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0165 0.1331 0.5104
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0118 0.0837 0.314
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0117 0.082 0.3074
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0117 0.082 0.1613
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0385 0.363 0.7193
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0559 0.1507
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0095 0.0596 0.0595
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.013 0.0244
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0104 0.0685 0.3734
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0044 0.0063 0.0062
Onchocerca volvulus 0.0095 0.0596 0.1528
Loa Loa (eye worm) AUR protein kinase 0.0151 0.118 0.1179
Loa Loa (eye worm) hypothetical protein 0.0195 0.1644 0.1644
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0559 0.1507
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0611 0.166
Brugia malayi Immunoglobulin I-set domain containing protein 0.0046 0.0079 0.0078
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0177 0.145 0.1449
Schistosoma mansoni netrin receptor unc5 0.0042 0.0038 0.0078
Schistosoma mansoni serine/threonine protein kinase 0.027 0.242 0.4989
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0072 0.0357 0.0692
Echinococcus granulosus casein kinase I delta 0.0112 0.0772 0.1517
Schistosoma mansoni serine/threonine protein kinase 0.0083 0.0471 0.0971
Schistosoma mansoni protein kinase 0.0103 0.0677 0.1396
Giardia lamblia Kinase, AGC AKT 0.0121 0.0865 0.3022
Echinococcus multilocularis Immunoglobulin 0.0051 0.0135 0.0252
Loa Loa (eye worm) hypothetical protein 0.0091 0.055 0.0549
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0177 0.145 0.1449
Brugia malayi Protein kinase domain containing protein 0.0367 0.344 0.3439
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0559 0.1507
Loa Loa (eye worm) hypothetical protein 0.0054 0.0162 0.0161
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0177 0.145 0.2863
Plasmodium falciparum serine/threonine protein kinase, putative 0.0151 0.118 0.6629
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0057 0.0198 0.0197
Loa Loa (eye worm) hypothetical protein 0.0177 0.145 0.1449
Echinococcus multilocularis serine:threonine protein kinase N2 0.0137 0.1035 0.204
Trichomonas vaginalis STE family protein kinase 0.0141 0.1076 0.3033
Echinococcus multilocularis nAChR subunit 0.0177 0.145 0.2863
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0677 0.1857
Entamoeba histolytica protein kinase, putative 0.0182 0.1504 0.3921
Loa Loa (eye worm) hypothetical protein 0.0044 0.0063 0.0062
Brugia malayi RhoGAP domain containing protein 0.0044 0.0063 0.0062
Entamoeba histolytica protein kinase domain containing protein 0.0212 0.1813 0.4735
Onchocerca volvulus 0.0177 0.145 0.372
Echinococcus multilocularis nAChR subunit 0.0095 0.0596 0.1168
Trypanosoma cruzi cdc2-related kinase 3 0.0123 0.0884 0.3328
Brugia malayi hypothetical protein 0.0082 0.0453 0.0452
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0206 0.1756 0.6794
Brugia malayi serine/threonine kinase 12 0.0151 0.118 0.1179
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0611 0.1259
Schistosoma mansoni serine/threonine protein kinase 0.0228 0.1981 0.4084
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0159 0.1265 0.1264
Plasmodium vivax protein kinase Crk2 0.0123 0.0884 0.4899
Leishmania major protein kinase, putative 0.016 0.127 0.4863
Loa Loa (eye worm) hypothetical protein 0.0118 0.0837 0.0836
Trichomonas vaginalis CMGC family protein kinase 0.0123 0.0884 0.2467
Leishmania major protein kinase, putative,serine/threonine-protein kinase Nek1, putative 0.0051 0.013 0.0329
Entamoeba histolytica protein kinase, putative 0.0104 0.0685 0.1762
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0118 0.0837 0.1726
Echinococcus granulosus rho-associated protein kinase 1 0.0341 0.3169 0.6278
Loa Loa (eye worm) hypothetical protein 0.0082 0.0453 0.0452
Schistosoma mansoni protein kinase 0.0456 0.4374 0.9017
Onchocerca volvulus 0.0046 0.0079 0.0201
Echinococcus granulosus glycine receptor subunit alpha 1 0.0177 0.145 0.2863
Echinococcus granulosus nAChR subunit 0.0095 0.0596 0.1168
Leishmania major casein kinase, putative 0.0112 0.0772 0.2881
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0085 0.0489 0.1756
Entamoeba histolytica protein kinase, putative 0.0072 0.0353 0.0886
Onchocerca volvulus 0.0177 0.145 0.372
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0411 0.3895 0.7719
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0183 0.1515 0.1515
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0165 0.1331 0.3783
Echinococcus multilocularis ephrin type A receptor 4 A 0.0085 0.0494 0.0964
Echinococcus granulosus activin receptor type 0.005 0.0119 0.022
Onchocerca volvulus 0.0112 0.0772 0.198
Entamoeba histolytica protein kinase domain containing protein 0.0133 0.0994 0.2575
Echinococcus multilocularis Rac GTPase activating protein 1 0.0044 0.0063 0.0108
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0082 0.0453 0.0452
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0227 0.1979 0.1978
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0177 0.145 0.1449
Echinococcus multilocularis cyclin dependent kinase 0.0123 0.0884 0.174
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0212 0.1813 0.1812
Loa Loa (eye worm) hypothetical protein 0.0147 0.1136 0.1136
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0104 0.0685 0.0684
Toxoplasma gondii AGC kinase 0.0117 0.082 0.2357
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0052 0.0147 0.0146
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0126 0.0922 0.348
Echinococcus granulosus STE20 serine:threonine protein kinase 0.052 0.5043 1
Loa Loa (eye worm) ACC-1 protein 0.0177 0.145 0.1449
Trypanosoma brucei protein kinase, putative 0.0086 0.0496 0.1322
Entamoeba histolytica protein kinase, putative 0.0043 0.0047 0.0079
Schistosoma mansoni tyrosine kinase 0.0072 0.0357 0.0735
Trichomonas vaginalis CMGC family protein kinase 0.0086 0.0496 0.1322
Schistosoma mansoni protein kinase 0.005 0.0119 0.0245
Echinococcus granulosus protein kinase shaggy 0.0133 0.0994 0.1957
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0165 0.1331 0.5104
Loa Loa (eye worm) hypothetical protein 0.006 0.0225 0.0224
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0086 0.0496 0.1784
Plasmodium falciparum calcium-dependent protein kinase 1 0.0104 0.0685 0.3734
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0243 0.2139 0.2138
Loa Loa (eye worm) hypothetical protein 0.0118 0.0832 0.0831
Brugia malayi Immunoglobulin I-set domain containing protein 0.0411 0.3896 0.3896
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0104 0.0685 0.1345
Schistosoma mansoni serine/threonine protein kinase 0.0277 0.2495 0.5144
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0095 0.0596 0.0595
Trypanosoma cruzi casein kinase, putative 0.0112 0.0772 0.2881
Schistosoma mansoni serine/threonine protein kinase 0.037 0.3473 0.716
Echinococcus granulosus serine threonine protein kinase nrc 0.0206 0.1756 0.3471
Giardia lamblia Kinase, STE STE20 0.0088 0.0521 0.1608
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0123 0.0884 0.0883
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0183 0.1509 0.2982
Loa Loa (eye worm) hypothetical protein 0.0065 0.0277 0.0276
Echinococcus granulosus defective proboscis extension response 0.0051 0.0135 0.0252
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0126 0.0922 0.348
Echinococcus granulosus serine:threonine protein kinase N2 0.0137 0.1035 0.204
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0246 0.2171 0.4296
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0087 0.0506 0.1289
Trichomonas vaginalis CMGC family protein kinase 0.0144 0.1108 0.3125
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.005 0.0119 0.0284
Schistosoma mansoni serine/threonine protein kinase 0.0126 0.0922 0.1901
Loa Loa (eye worm) hypothetical protein 0.0082 0.0453 0.0452
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0117 0.082 0.2357
Entamoeba histolytica protein kinase domain containing protein 0.005 0.0119 0.0267
Schistosoma mansoni serine/threonine protein kinase 0.016 0.127 0.2618
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0104 0.0685 0.1946
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0055 0.0174 0.0173
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0057 0.0193 0.0368
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0104 0.0685 0.188
Schistosoma mansoni serine/threonine kinase 0.0182 0.1504 0.3101
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0177 0.145 0.2988
Echinococcus granulosus serine:threonine protein kinase 0.0118 0.0832 0.1637
Loa Loa (eye worm) hypothetical protein 0.0082 0.0453 0.0452
Loa Loa (eye worm) hypothetical protein 0.0044 0.0063 0.0062
Entamoeba histolytica hypothetical protein 0.0095 0.0596 0.1526
Loa Loa (eye worm) hypothetical protein 0.0082 0.0453 0.0452
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0117 0.082 0.4524
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0092 0.0559 0.2033
Schistosoma mansoni serine/threonine protein kinase 0.0123 0.0884 0.1823
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0082 0.0453 0.0883
Loa Loa (eye worm) hypothetical protein 0.0177 0.145 0.1449
Echinococcus multilocularis nervana 2 0.0174 0.1422 0.2807
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0117 0.082 0.1613
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0209 0.1791 0.3542
Entamoeba histolytica p21-activated kinase 0.0099 0.0635 0.1629
Echinococcus multilocularis nervana 2 0.0174 0.1422 0.2807
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0206 0.1756 0.3471
Schistosoma mansoni serine/threonine protein kinase 0.0212 0.1813 0.3737
Loa Loa (eye worm) AGC/PKA protein kinase 0.0117 0.082 0.0819
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0269 0.2413 0.2412
Loa Loa (eye worm) hypothetical protein 0.0177 0.145 0.1449
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0086 0.0496 0.1784
Echinococcus granulosus casein kinase i 0.0112 0.0772 0.1517
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0228 0.1981 0.198
Brugia malayi Doublecortin family protein 0.0157 0.1239 0.1238
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0353 0.3288 0.3287
Brugia malayi hypothetical protein 0.0232 0.2029 0.2029
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0088 0.0521 0.1019
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0472 0.4536 0.4535
Trichomonas vaginalis AGC family protein kinase 0.0182 0.1504 0.4293
Echinococcus granulosus protein kinase C gamma type 0.0225 0.1957 0.3871
Loa Loa (eye worm) hypothetical protein 0.0095 0.0596 0.0595
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0174 0.1422 0.2807
Brugia malayi Protein kinase domain containing protein 0.0472 0.4536 0.4535
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0151 0.118 0.6629
Onchocerca volvulus 0.0177 0.145 0.372
Trichomonas vaginalis AGC family protein kinase 0.0117 0.082 0.2278
Echinococcus granulosus casein kinase I alpha 0.0112 0.0772 0.1517
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0177 0.145 0.2988
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0182 0.1504 0.2971
Schistosoma mansoni serine/threonine protein kinase 0.016 0.127 0.2618
Trichomonas vaginalis STE family protein kinase 0.0088 0.0521 0.1396
Loa Loa (eye worm) hypothetical protein 0.0117 0.082 0.0819
Loa Loa (eye worm) TK protein kinase 0.0057 0.0193 0.0192
Loa Loa (eye worm) hypothetical protein 0.0054 0.0162 0.0161
Entamoeba histolytica protein kinase, putative 0.0151 0.118 0.3066
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0677 0.1857
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0177 0.145 0.1449
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0083 0.0471 0.047
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0072 0.0357 0.0692
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0104 0.0685 0.1345
Schistosoma mansoni protein kinase 0.0159 0.1265 0.2607
Giardia lamblia Kinase, NEK 0.0141 0.1076 0.3891
Trichomonas vaginalis AGC family protein kinase 0.0367 0.344 1
Echinococcus granulosus Rac GTPase activating protein 1 0.0044 0.0063 0.0108
Echinococcus granulosus tyrosine protein kinase Src64B 0.0072 0.0357 0.0692
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0271 0.2435 0.2435
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0085 0.0489 0.1756
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0271 0.2435 0.4821
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0177 0.145 0.2863
Schistosoma mansoni protein kinase 0.0065 0.0281 0.0579
Echinococcus multilocularis netrin receptor unc 5 0.0042 0.0038 0.0059
Schistosoma mansoni serine/threonine protein kinase 0.0183 0.1509 0.3112
Echinococcus granulosus dual specificity 0.0144 0.1108 0.2184
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.021 0.1792 0.1791
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0092 0.0559 0.2033
Echinococcus multilocularis mitogen activated protein kinase 0.0086 0.0496 0.0969
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0411 0.3895 0.7719
Trypanosoma cruzi casein kinase, delta isoform, putative 0.008 0.0438 0.1553
Loa Loa (eye worm) hypothetical protein 0.0177 0.145 0.1449
Echinococcus granulosus titin 0.0046 0.0079 0.0142
Echinococcus granulosus glycine receptor subunit alpha 1 0.0177 0.145 0.2863
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0072 0.0357 0.0692
Echinococcus granulosus mitogen activated protein kinase 14 0.0165 0.1331 0.2627
Brugia malayi Protein kinase domain containing protein 0.0118 0.0832 0.0831
Echinococcus multilocularis activin receptor type 0.005 0.0119 0.022
Schistosoma mansoni vesicular amine transporter 0.0051 0.0135 0.0278
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.0559 0.1152
Echinococcus granulosus casein kinase ii subunit alpha 0.0103 0.0677 0.1329
Echinococcus granulosus tyrosine protein kinase Lyn 0.0104 0.0691 0.1356
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0177 0.145 0.1449
Giardia lamblia Kinase, CMGC GSK 0.0133 0.0994 0.355
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.015 0.1171 0.231
Entamoeba histolytica protein kinase domain containing protein 0.0103 0.0677 0.1741
Loa Loa (eye worm) TK/EPH protein kinase 0.0104 0.0688 0.0687
Loa Loa (eye worm) hypothetical protein 0.0086 0.0502 0.0501
Entamoeba histolytica diacylglycerol kinase, putative 0.0044 0.0063 0.0119
Loa Loa (eye worm) hypothetical protein 0.0488 0.4709 0.4709
Brugia malayi hypothetical protein 0.0118 0.0837 0.0836
Echinococcus granulosus cyclin dependent kinase 5 0.0123 0.0884 0.174
Echinococcus multilocularis casein kinase I delta 0.0112 0.0772 0.1517
Brugia malayi Serine/threonine-protein kinase Pim-3 0.037 0.3473 0.3472
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0177 0.145 0.2863
Echinococcus granulosus serine:threonine protein kinase 3 0.0269 0.2413 0.4776
Brugia malayi Protein kinase domain containing protein 0.0206 0.1753 0.1752
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0411 0.3895 0.3894
Plasmodium falciparum NIMA related kinase 1 0.0141 0.1076 0.6023
Trichomonas vaginalis AGC family protein kinase 0.0083 0.0471 0.1248
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0044 0.0063 0.0062
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0041 0.0032 0.0048
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0194 0.1626 0.1625
Schistosoma mansoni serine/threonine protein kinase 0.0104 0.0685 0.1413
Onchocerca volvulus 0.0082 0.0453 0.116
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0112 0.0772 0.2881
Schistosoma mansoni serine/threonine protein kinase 0.0283 0.2562 0.5281
Loa Loa (eye worm) hypothetical protein 0.0082 0.0453 0.0452
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0559 0.1507
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0144 0.1108 0.3234
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0041 0.0032 0.0066
Schistosoma mansoni unc-13 (munc13) 0.0046 0.0077 0.0158
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0214 0.1841 0.3639
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0177 0.145 0.2863
Toxoplasma gondii histone kinase SNF1, putative 0.0092 0.0559 0.1559
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0206 0.1756 1
Entamoeba histolytica protein kinase, putative 0.0356 0.3326 0.8727
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0283 0.2562 0.5071
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0104 0.0685 0.1946
Onchocerca volvulus 0.0177 0.145 0.372
Echinococcus multilocularis mitogen activated protein kinase 3 0.0086 0.0496 0.0969
Entamoeba histolytica casein kinase, putative 0.0112 0.0772 0.199
Echinococcus multilocularis glycine receptor subunit beta 0.0177 0.145 0.2863
Onchocerca volvulus 0.0195 0.1644 0.422
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0083 0.0471 0.0919
Schistosoma mansoni tyrosine kinase 0.0238 0.2088 0.4304
Brugia malayi protein-tyrosine kinase 0.0057 0.0193 0.0192
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0086 0.0496 0.1784
Schistosoma mansoni diacylglycerol kinase theta 0.0044 0.0063 0.0129
Entamoeba histolytica protein kinase , putative 0.0151 0.118 0.3066
Brugia malayi hypothetical protein 0.0082 0.0453 0.0452
Plasmodium vivax unspecified product 0.0103 0.0677 0.3687
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0194 0.1626 0.1625
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0082 0.0453 0.0452
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0245 0.2168 0.429
Brugia malayi Protein kinase domain containing protein 0.0385 0.363 0.363
Trypanosoma cruzi NIMA-related kinase, putative 0.0051 0.013 0.0329
Toxoplasma gondii aurora kinase 0.0151 0.118 0.3454
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0072 0.0353 0.0685
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0082 0.0453 0.0452
Echinococcus multilocularis casein kinase I alpha 0.0112 0.0772 0.1517
Loa Loa (eye worm) hypothetical protein 0.0082 0.0453 0.0452
Loa Loa (eye worm) hypothetical protein 0.006 0.0225 0.0224
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0144 0.1108 0.4217
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0104 0.0685 0.1345
Loa Loa (eye worm) hypothetical protein 0.0044 0.0063 0.0062
Loa Loa (eye worm) hypothetical protein 0.0177 0.145 0.1449
Loa Loa (eye worm) hypothetical protein 0.0082 0.0453 0.0452
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0083 0.0466 0.1276
Loa Loa (eye worm) AGC/AKT protein kinase 0.0367 0.344 0.3439
Plasmodium falciparum casein kinase 2, alpha subunit 0.0103 0.0677 0.3687
Trypanosoma cruzi p21-activated kinase 3, putative 0.0055 0.0174 0.0502
Brugia malayi Protein kinase domain containing protein 0.0182 0.1504 0.1503
Schistosoma mansoni hypothetical protein 0.0044 0.0063 0.0129
Schistosoma mansoni serine/threonine protein kinase 0.0267 0.2393 0.4933
Loa Loa (eye worm) TK/INSR protein kinase 0.0206 0.1753 0.1752
Echinococcus granulosus protein kinase 0.0159 0.1265 0.2495
Echinococcus multilocularis mitogen activated protein kinase 14 0.0165 0.1331 0.2627
Trichomonas vaginalis CAMK family protein kinase 0.0131 0.0968 0.2714
Echinococcus multilocularis N chimaerin 0.0052 0.0147 0.0275
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.016 0.127 0.3729
Plasmodium falciparum NIMA related kinase 4 0.0051 0.013 0.0485
Trichomonas vaginalis CK1 family protein kinase 0.0112 0.0772 0.2136
Schistosoma mansoni serine/threonine protein kinase 0.0502 0.4851 1
Loa Loa (eye worm) hypothetical protein 0.0094 0.0588 0.0587
Leishmania major protein kinase, putative 0.016 0.127 0.4863
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0092 0.0559 0.2033
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0051 0.0135 0.0278
Toxoplasma gondii casein kinase I 0.0112 0.0772 0.221
Onchocerca volvulus 0.0177 0.145 0.372
Trypanosoma brucei cdc2-related kinase 1 0.0123 0.0884 0.2467
Onchocerca volvulus 0.0095 0.0596 0.1528
Loa Loa (eye worm) TK protein kinase 0.0049 0.0109 0.0108
Leishmania major protein kinase, putative 0.0151 0.118 0.4504
Entamoeba histolytica protein kinase, putative 0.0085 0.0489 0.1244
Loa Loa (eye worm) acetylcholine receptor protein 0.0082 0.0453 0.0452
Trypanosoma cruzi casein kinase, putative 0.0112 0.0772 0.2881
Schistosoma mansoni tyrosine kinase 0.0051 0.0132 0.0272
Schistosoma mansoni acetylcholine receptor-related 0.0082 0.0453 0.0934
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0104 0.0685 0.1946
Loa Loa (eye worm) hypothetical protein 0.0177 0.145 0.1449
Leishmania major protein kinase, putative 0.0051 0.013 0.0329
Loa Loa (eye worm) thyroid receptor interactor 0.0092 0.0558 0.0557
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0112 0.0772 0.0771
Loa Loa (eye worm) hypothetical protein 0.0177 0.145 0.1449
Trichomonas vaginalis CMGC family protein kinase 0.0086 0.0496 0.1322
Trichomonas vaginalis CMGC family protein kinase 0.0123 0.0884 0.2467
Echinococcus granulosus glycine receptor subunit beta 0.0177 0.145 0.2863
Echinococcus multilocularis cGMP dependent protein kinase 1 0.014 0.1059 0.2087
Loa Loa (eye worm) hypothetical protein 0.0147 0.1136 0.1136
Giardia lamblia Kinase, CMGC GSK 0.0133 0.0994 0.355
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0144 0.1108 0.1107
Echinococcus multilocularis cyclin dependent kinase 5 0.0123 0.0884 0.174
Loa Loa (eye worm) hypothetical protein 0.0095 0.0596 0.0595
Echinococcus multilocularis mitogen activated protein kinase 11 0.0165 0.1331 0.2627
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0087 0.0506 0.1289
Brugia malayi STE20-like kinase MST 0.0269 0.2413 0.2412
Echinococcus granulosus twitchin 0.0094 0.0588 0.1152
Schistosoma mansoni vav2 0.0063 0.026 0.0537
Entamoeba histolytica protein kinase, putative 0.0072 0.0353 0.0886
Loa Loa (eye worm) ACC-1 protein 0.0177 0.145 0.1449
Brugia malayi Pleckstrin Homology Domain 0.0055 0.0177 0.0176
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0053 0.0109
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0112 0.0772 0.0771
Loa Loa (eye worm) hypothetical protein 0.0094 0.0588 0.0587
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0133 0.0994 0.2886
Echinococcus granulosus insulin receptor 0.0206 0.1753 0.3464
Plasmodium vivax serine/threonine-protein kinase Nek1, putative 0.0051 0.013 0.0485
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0046 0.0077 0.0136
Brugia malayi SRC-1 0.0072 0.0357 0.0356
Brugia malayi Protein kinase domain containing protein 0.0223 0.193 0.1929
Loa Loa (eye worm) hypothetical protein 0.0055 0.0177 0.0176
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0411 0.3895 0.3894
Loa Loa (eye worm) hypothetical protein 0.0044 0.0063 0.0062
Echinococcus multilocularis myotubularin protein 13 0.0055 0.0177 0.0335
Trypanosoma cruzi Serine/threonine-protein kinase NEK16, putative 0.0051 0.013 0.0329
Loa Loa (eye worm) hypothetical protein 0.0118 0.0837 0.0836
Trichomonas vaginalis AGC family protein kinase 0.0367 0.344 1
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.016 0.127 0.4863
Schistosoma mansoni serine/threonine protein kinase 0.0223 0.193 0.3979
Echinococcus multilocularis epidermal growth factor receptor 0.0164 0.1319 0.2604
Schistosoma mansoni nAChR subunit 0.0177 0.145 0.2988
Entamoeba histolytica protein kinase, putative 0.0144 0.1108 0.2876
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0088 0.0521 0.1019
Echinococcus multilocularis protein kinase c eta type 0.0044 0.0063 0.0108
Giardia lamblia Kinase, STE STE20 0.0087 0.0506 0.1546
Echinococcus multilocularis dual specificity 0.0144 0.1108 0.2184
Loa Loa (eye worm) hypothetical protein 0.0082 0.0453 0.0452
Echinococcus granulosus netrin receptor unc 5 0.0042 0.0038 0.0059
Echinococcus granulosus epidermal growth factor receptor 0.0238 0.2088 0.413
Loa Loa (eye worm) hypothetical protein 0.0095 0.0596 0.0595
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0052 0.0147 0.0302
Loa Loa (eye worm) hypothetical protein 0.0177 0.145 0.1449
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0118 0.0837 0.1726
Echinococcus multilocularis tyrosine protein kinase Abl 0.0041 0.0032 0.0048
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0177 0.145 0.2863
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0559 0.1507
Schistosoma mansoni protein kinase 0.0214 0.1841 0.3795
Echinococcus multilocularis expressed conserved protein 0.014 0.1059 0.2087
Leishmania major protein kinase A catalytic subunit isoform 1 0.0117 0.082 0.3074
Schistosoma mansoni tyrosine kinase 0.004 0.0022 0.0045
Trypanosoma cruzi casein kinase, putative 0.0112 0.0772 0.2881
Loa Loa (eye worm) AGC/PKA protein kinase 0.0117 0.082 0.0819
Toxoplasma gondii diacylglycerol kinase, putative 0.0044 0.0063 0.0046
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0144 0.1108 0.3125
Echinococcus granulosus cyclin dependent kinase 0.0123 0.0884 0.174
Trypanosoma cruzi cdc2-related kinase 1 0.0123 0.0884 0.3328
Brugia malayi serine/threonine-protein kinase 6 0.0151 0.118 0.1179
Loa Loa (eye worm) hypothetical protein 0.0082 0.0453 0.0452
Onchocerca volvulus 0.0082 0.0453 0.116
Brugia malayi protein unc-22 0.0046 0.0079 0.0078
Echinococcus multilocularis cGMP dependent protein kinase 1 0.014 0.1059 0.2087
Schistosoma mansoni protein kinase C mu 0.0227 0.1979 0.4079
Entamoeba histolytica hypothetical protein 0.0044 0.0063 0.0119
Loa Loa (eye worm) hypothetical protein 0.0206 0.1758 0.1757
Echinococcus granulosus Diacylglycerol kinase theta 0.0044 0.0063 0.0108
Loa Loa (eye worm) AGC/PKN protein kinase 0.0319 0.294 0.2939
Echinococcus granulosus calcium dependent protein kinase 0.0072 0.0351 0.0682
Echinococcus granulosus tyrosine protein kinase Blk 0.0057 0.0193 0.0368
Loa Loa (eye worm) hypothetical protein 0.0104 0.0685 0.0684
Toxoplasma gondii CMGC kinase, CK2 family 0.0103 0.0677 0.1921
Echinococcus multilocularis raf serine:threonine protein kinase 0.0062 0.0248 0.0476
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.037 0.3473 0.6881
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0123 0.0882 0.1737
Loa Loa (eye worm) hypothetical protein 0.0095 0.0596 0.0595
Echinococcus granulosus unc 13 munc13 0.0046 0.0077 0.0136
Plasmodium falciparum protein serine/threonine kinase-1 0.016 0.127 0.7157
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0177 0.145 0.1449
Echinococcus multilocularis protein kinase c iota type 0.0314 0.2885 0.5714
Schistosoma mansoni tyrosine kinase 0.0147 0.1134 0.2338
Loa Loa (eye worm) hypothetical protein 0.0177 0.145 0.1449
Schistosoma mansoni serine/threonine protein kinase 0.0246 0.2171 0.4476
Schistosoma mansoni vam6/vps39 related 0.0118 0.0837 0.1726
Loa Loa (eye worm) hypothetical protein 0.0128 0.0936 0.0935
Trichomonas vaginalis AGC family protein kinase 0.0367 0.344 1
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0104 0.0685 0.0684
Trichomonas vaginalis CAMK family protein kinase 0.0118 0.0832 0.2314
Schistosoma mansoni nAChR subunit 0.0082 0.0453 0.0934
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0088 0.0521 0.1019
Echinococcus multilocularis rho associated protein kinase 0.0341 0.3169 0.6278
Echinococcus granulosus cGMP dependent protein kinase 1 0.014 0.1059 0.2087
Entamoeba histolytica protein kinase, putative 0.0043 0.0047 0.0079
Loa Loa (eye worm) CAMK/PIM protein kinase 0.037 0.3473 0.3472
Toxoplasma gondii NEK kinase 0.0051 0.013 0.0253
Echinococcus granulosus Protein kinase C brain isozyme 0.027 0.242 0.479
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0082 0.0453 0.0452
Entamoeba histolytica PH domain containing protein kinase, putative 0.0128 0.0934 0.2418
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0123 0.0884 0.3328
Schistosoma mansoni serine/threonine protein kinase 0.014 0.1059 0.2184
Brugia malayi Variant SH3 domain containing protein 0.0052 0.0147 0.0146
Leishmania major protein kinase A catalytic subunit isoform 2 0.0117 0.082 0.3074
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.016 0.127 0.3604
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0088 0.0521 0.1019
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0212 0.1813 0.1812
Schistosoma mansoni hypothetical protein 0.0065 0.0277 0.057
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0677 0.1857
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0177 0.145 0.2863
Schistosoma mansoni diacylglycerol kinase theta 0.0044 0.0063 0.0129
Onchocerca volvulus Serine\/threonine kinase homolog 0.0283 0.2562 0.6576
Brugia malayi Protein kinase domain containing protein 0.0083 0.0471 0.047
Echinococcus granulosus expressed protein 0.0085 0.0489 0.0955
Entamoeba histolytica protein kinase, putative 0.0085 0.0489 0.1244
Schistosoma mansoni protein kinase 0.0456 0.4374 0.9017
Onchocerca volvulus 0.0133 0.0994 0.2549
Brugia malayi Protein kinase domain containing protein 0.0123 0.0884 0.0883
Trichomonas vaginalis CMGC family protein kinase 0.016 0.127 0.3604
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0177 0.145 0.1449
Loa Loa (eye worm) GABA receptor subunit 0.0095 0.0596 0.0595
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0117 0.082 0.1613
Echinococcus granulosus titin 0.0046 0.0079 0.0142
Brugia malayi p70 ribosomal S6 kinase beta 0.0356 0.3326 0.3325
Echinococcus multilocularis serine threonine protein kinase 0.0225 0.1957 0.3871
Entamoeba histolytica hypothetical protein 0.0126 0.0922 0.2387
Loa Loa (eye worm) hypothetical protein 0.0095 0.0596 0.0595
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0123 0.0884 0.3328
Echinococcus multilocularis casein kinase I delta 0.0112 0.0772 0.1517
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0183 0.1509 0.2982
Trichomonas vaginalis CAMK family protein kinase 0.0283 0.2562 0.7411
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0072 0.0357 0.0692
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0118 0.0837 0.1646
Echinococcus granulosus nervana 2 0.0174 0.1422 0.2807
Trichomonas vaginalis AGC family protein kinase 0.0367 0.344 1
Entamoeba histolytica hypothetical protein 0.0043 0.0047 0.0079
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0082 0.0453 0.0452
Echinococcus granulosus cGMP dependent protein kinase 1 0.014 0.1059 0.2087
Echinococcus granulosus protein kinase c epsilon type 0.0228 0.1981 0.3918
Schistosoma mansoni neurotransmitter gated ion channel 0.0095 0.0596 0.1229
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0414 0.3934 0.3933
Echinococcus granulosus tyrosine protein kinase Src42A 0.0072 0.0357 0.0692
Trichomonas vaginalis AGC family protein kinase 0.0182 0.1504 0.4293
Giardia lamblia Kinase, CAMK CAMKL 0.0092 0.0559 0.1762
Schistosoma mansoni serine/threonine protein kinase 0.0319 0.294 0.6061
Echinococcus multilocularis calcium activated potassium channel 0.0097 0.0611 0.1197
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0123 0.0884 0.174
Trypanosoma brucei Serine/threonine-protein kinase NEK11, putative 0.0051 0.013 0.0244
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0182 0.1504 0.2971
Echinococcus granulosus RNA directed DNA polymerase 0.0042 0.0039 0.0061
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.0559 0.1152
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0104 0.0685 0.3734
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0141 0.1076 0.6023
Entamoeba histolytica casein kinase, putative 0.0103 0.0677 0.1741
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.005 0.0119 0.0218
Echinococcus granulosus aurora kinase A 0.0151 0.118 0.2327
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0611 0.1259
Echinococcus multilocularis expressed protein 0.0085 0.0489 0.0955
Echinococcus granulosus serine:threonine protein kinase N2 0.0319 0.294 0.5822
Trichomonas vaginalis CMGC family protein kinase 0.0086 0.0496 0.1322
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0046 0.0079 0.0078
Entamoeba histolytica protein kinase, putative 0.0367 0.344 0.9028
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0088 0.0521 0.1019
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0456 0.4374 0.867
Trichomonas vaginalis CAMK family protein kinase 0.0283 0.2562 0.7411
Schistosoma mansoni serine/threonine protein kinase 0.0183 0.1509 0.3112
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0177 0.145 0.2988
Schistosoma mansoni serine/threonine protein kinase 0.0144 0.1108 0.2284
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0133 0.0994 0.0993
Schistosoma mansoni protein kinase 0.0277 0.2502 0.5158
Schistosoma mansoni rac gtpase activating protein 0.0044 0.0063 0.0129
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.013 0.0244
Entamoeba histolytica protein kinase, putative 0.0126 0.0922 0.2387
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0559 0.1507
Brugia malayi Protein kinase domain containing protein 0.0085 0.0489 0.0488
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0414 0.3934 0.7797
Brugia malayi putative serine/threonine kinase SADA gamma 0.0092 0.0559 0.0558
Echinococcus multilocularis 0.0159 0.1265 0.2495
Brugia malayi Furin-like cysteine rich region family protein 0.0238 0.2088 0.2087
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0086 0.0496 0.1784
Trichomonas vaginalis CMGC family protein kinase 0.0086 0.0496 0.1322
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.052 0.5043 1
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0095 0.0596 0.1229
Schistosoma mansoni tyrosine kinase 0.0147 0.1134 0.2338
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0086 0.0496 0.0495
Trichomonas vaginalis STE family protein kinase 0.0088 0.0521 0.1396
Giardia lamblia Kinase, CAMK CAMKL 0.0092 0.0559 0.1762
Brugia malayi RhoGAP domain containing protein 0.0052 0.0147 0.0146
Loa Loa (eye worm) hypothetical protein 0.0177 0.145 0.1449
Schistosoma mansoni serine/threonine protein kinase 0.0151 0.118 0.2432
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0277 0.2495 0.2494
Leishmania major protein kinase, putative 0.0087 0.0506 0.1824
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0055 0.0174 0.0173
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0087 0.0506 0.1352
Brugia malayi hypothetical protein 0.0082 0.0453 0.0452
Brugia malayi casein kinase 1, delta 0.0112 0.0772 0.0771
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0144 0.1108 0.1107
Brugia malayi Fibronectin type III domain containing protein 0.0054 0.0162 0.0161
Plasmodium falciparum calcium-dependent protein kinase 5 0.0104 0.0685 0.3734
Leishmania major protein kinase, putative 0.005 0.0119 0.0284
Trichomonas vaginalis AGC family protein kinase 0.0182 0.1504 0.4293
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0117 0.082 0.1613
Echinococcus multilocularis protein kinase c epsilon type 0.0228 0.1981 0.3918
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.013 0.0244
Giardia lamblia Kinase, AGC PKA 0.0206 0.1756 0.6685
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0133 0.0994 0.1957
Plasmodium vivax calcium-dependent protein kinase, putative 0.0104 0.0685 0.3734
Echinococcus multilocularis protein kinase shaggy 0.0133 0.0994 0.1957
Leishmania major protein kinase A catalytic subunit 0.0117 0.082 0.3074
Echinococcus granulosus calcium activated potassium channel 0.0097 0.0611 0.1197
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0117 0.082 0.2278
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0062 0.0253 0.0487
Schistosoma mansoni protein kinase 0.0214 0.1841 0.3795
Trichomonas vaginalis CAMK family protein kinase 0.0283 0.2562 0.7411
Echinococcus multilocularis Glutaredoxin protein 5 0.0174 0.1422 0.2807
Trichomonas vaginalis CMGC family protein kinase 0.0133 0.0994 0.2789
Schistosoma mansoni tyrosine kinase 0.0123 0.0882 0.1819
Trypanosoma brucei rac serine-threonine kinase, putative 0.0367 0.344 1
Schistosoma mansoni tyrosine kinase 0.0206 0.1753 0.3613
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0559 0.1507
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0133 0.0994 0.3763
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0559 0.1507
Echinococcus multilocularis casein kinase I gamma 0.0223 0.193 0.3817
Schistosoma mansoni serine/threonine protein kinase 0.0246 0.2171 0.4476
Entamoeba histolytica protein kinase, putative 0.0105 0.0699 0.1799
Brugia malayi Fes/CIP4 homology domain containing protein 0.0092 0.0558 0.0557
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0042 0.0039 0.0061
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0118 0.0837 0.314
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0283 0.2562 0.2561
Brugia malayi Protein kinase domain containing protein 0.016 0.127 0.1269
Entamoeba histolytica serine/threonine protein kinase, putative 0.0092 0.0559 0.1428
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0083 0.0471 0.047
Loa Loa (eye worm) hypothetical protein 0.0147 0.1136 0.1136
Loa Loa (eye worm) TK protein kinase 0.0134 0.1002 0.1001
Trichomonas vaginalis CMGC family protein kinase 0.0144 0.1108 0.3125
Echinococcus granulosus mitogen activated protein kinase 11 0.0165 0.1331 0.2627
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0177 0.145 0.2863
Trichomonas vaginalis CMGC family protein kinase 0.0133 0.0994 0.2789
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0133 0.0994 0.3763
Trichomonas vaginalis AGC family protein kinase 0.0083 0.0471 0.1248
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.0685 0.188
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0171 0.1386 0.2736
Echinococcus multilocularis serine:threonine protein kinase 0.0118 0.0832 0.1637
Echinococcus granulosus serine:threonine protein kinase 0.0118 0.0832 0.1637
Echinococcus granulosus serine:threonine kinase SAD 1 0.0092 0.0559 0.1094
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0075 0.0387 0.0386
Schistosoma mansoni serine/threonine protein kinase 0.0123 0.0884 0.1823
Brugia malayi Immunoglobulin I-set domain containing protein 0.0134 0.1002 0.1001
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0212 0.1813 0.3584
Loa Loa (eye worm) AGC/NDR protein kinase 0.0182 0.1504 0.1503
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0085 0.0489 0.1347
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0082 0.0453 0.0452
Schistosoma mansoni tyrosine kinase 0.0164 0.1319 0.272
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0104 0.0685 0.1345
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0414 0.3934 0.7797
Giardia lamblia Kinase, CMGC CDK 0.0123 0.0884 0.3101
Echinococcus multilocularis cyclin dependent kinase 1 0.0123 0.0884 0.174
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0117 0.082 0.3074
Echinococcus multilocularis tyrosine protein kinase Blk 0.0057 0.0193 0.0368
Onchocerca volvulus 0.0118 0.0837 0.2147
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0206 0.1756 0.3471
Echinococcus granulosus casein kinase I alpha 0.0112 0.0772 0.1517
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0123 0.0884 0.2552
Schistosoma mansoni serine/threonine protein kinase 0.0117 0.082 0.1691
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0082 0.0453 0.0883
Brugia malayi Tyrosine-protein kinase abl-1 0.0041 0.0032 0.0031
Entamoeba histolytica protein kinase, putative 0.0088 0.0521 0.1329
Trypanosoma cruzi Protein kinase B 0.0217 0.187 0.7247
Brugia malayi hypothetical protein 0.0082 0.0453 0.0452
Echinococcus multilocularis 0.0128 0.0936 0.1843
Echinococcus granulosus dual specificity 0.0126 0.0922 0.1816
Trichomonas vaginalis CMGC family protein kinase 0.0144 0.1108 0.3125
Trypanosoma brucei NIMA-related protein kinase 0.0051 0.013 0.0244
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0677 0.1857
Onchocerca volvulus 0.0082 0.0453 0.116
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0177 0.145 0.2988
Schistosoma mansoni nAChR subunit 0.0177 0.145 0.2988
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0177 0.145 0.2863
Leishmania major protein kinase, putative 0.0104 0.0685 0.2537
Giardia lamblia Kinase, NEK 0.0141 0.1076 0.3891
Plasmodium vivax serine/threonine kinase-1, putative 0.016 0.127 0.7157
Brugia malayi RhoGEF domain containing protein 0.0044 0.0063 0.0062
Trichomonas vaginalis STE family protein kinase 0.0065 0.0281 0.0688
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0051 0.013 0.0329
Brugia malayi phosphoinositide-dependent protein kinase I 0.0083 0.0471 0.047
Brugia malayi hypothetical protein 0.0082 0.0453 0.0452
Schistosoma mansoni cell adhesion molecule 0.0065 0.028 0.0577
Loa Loa (eye worm) hypothetical protein 0.0092 0.0559 0.0558
Brugia malayi Protein kinase domain containing protein 0.0097 0.0611 0.061
Loa Loa (eye worm) hypothetical protein 0.0074 0.0372 0.0371
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0112 0.0772 0.0771
Echinococcus multilocularis casein kinase ii subunit alpha 0.0103 0.0677 0.1329
Loa Loa (eye worm) AGC/PKG protein kinase 0.014 0.1059 0.1058
Giardia lamblia Kinase, CMGC MAPK 0.0086 0.0496 0.1504
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.005 0.0119 0.0284
Loa Loa (eye worm) hypothetical protein 0.0095 0.0596 0.0595
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0232 0.2029 0.4014
Loa Loa (eye worm) TK/EGFR protein kinase 0.0238 0.2088 0.2087
Brugia malayi Egg laying defective protein 4 0.014 0.1059 0.1058
Echinococcus granulosus casein kinase I gamma 0.0223 0.193 0.3817
Echinococcus multilocularis rac serine:threonine kinase 0.0217 0.187 0.3697
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0085 0.0486 0.095
Echinococcus granulosus raf serine:threonine protein kinase 0.0062 0.0248 0.0476
Echinococcus granulosus cyclin dependent kinase 1 0.0123 0.0884 0.174
Entamoeba histolytica protein kinase domain containing protein 0.0133 0.0994 0.2575
Loa Loa (eye worm) hypothetical protein 0.0151 0.1181 0.118
Loa Loa (eye worm) CMGC/CLK protein kinase 0.016 0.127 0.1269
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0072 0.0357 0.0692
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0144 0.1108 0.4217
Onchocerca volvulus 0.0206 0.1758 0.4513
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0177 0.145 0.2988
Echinococcus granulosus tyrosine protein kinase Fyn 0.0072 0.0357 0.0692
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0151 0.118 0.2327
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.016 0.127 0.4863
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.017 0.1382 0.1381
Giardia lamblia Kinase, CMGC SRPK 0.0085 0.0489 0.1475
Trichomonas vaginalis STE family protein kinase 0.0087 0.0506 0.1352
Trichomonas vaginalis CMGC family protein kinase 0.0144 0.1108 0.3125
Entamoeba histolytica serine/threonine protein kinase, putative 0.0283 0.2562 0.6711
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0177 0.145 0.1449
Brugia malayi serine/threonine-protein kinase PAK 7 0.0243 0.2139 0.2138
Echinococcus granulosus Vam6:Vps39 protein 0.0118 0.0837 0.1646
Loa Loa (eye worm) CAMK/PIM protein kinase 0.037 0.3473 0.3472
Schistosoma mansoni serine/threonine protein kinase 0.027 0.242 0.4989
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0092 0.0559 0.0558
Echinococcus multilocularis myosin iiia 0.0087 0.0506 0.0989
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0165 0.1331 0.133
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0038 0.0037
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0095 0.0596 0.0595
Brugia malayi protein kinase C II. 0.0228 0.1981 0.198
Schistosoma mansoni nAChR subunit 0.0177 0.145 0.2988
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0151 0.118 0.3066
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0177 0.145 0.1449
Giardia lamblia Kinase, CK1 Casein kinase 0.0112 0.0772 0.2639
Schistosoma mansoni nAChR subunit 0.0082 0.0453 0.0934
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0104 0.0685 0.0684
Trichomonas vaginalis AGC family protein kinase 0.0083 0.0471 0.1248
Entamoeba histolytica protein kinase, putative 0.0076 0.0395 0.0995
Schistosoma mansoni serine/threonine protein kinase 0.0182 0.1504 0.3101
Loa Loa (eye worm) hypothetical protein 0.0082 0.0453 0.0452
Loa Loa (eye worm) hypothetical protein 0.0042 0.0039 0.0038
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0994 1 1
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0171 0.1386 0.2736
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0117 0.082 0.2278
Trichomonas vaginalis STE family protein kinase 0.0088 0.0521 0.1396
Echinococcus granulosus tyrosine protein kinase Fyn 0.0072 0.0357 0.0692
Schistosoma mansoni serine/threonine protein kinase 0.0072 0.0353 0.0728
Schistosoma mansoni serine/threonine protein kinase 0.0182 0.1504 0.3101
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0411 0.3895 0.7719
Schistosoma mansoni protein kinase C mu 0.0044 0.0063 0.0129
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0117 0.082 0.0819
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0104 0.0685 0.1345
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0126 0.0922 0.2579
Brugia malayi C1-like domain containing protein 0.0227 0.1979 0.1978
Echinococcus multilocularis Diacylglycerol kinase theta 0.0044 0.0063 0.0108
Trichomonas vaginalis CK1 family protein kinase 0.0112 0.0772 0.2136
Echinococcus multilocularis tyrosine protein kinase HCK 0.0049 0.0109 0.0201
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0353 0.3288 0.3287
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.037 0.3473 0.6881
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0283 0.2562 0.5071
Brugia malayi Hr1 repeat family protein 0.0319 0.294 0.2939
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0104 0.0685 0.1345
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0085 0.0486 0.095
Schistosoma mansoni nAChR subunit 0.0177 0.145 0.2988
Giardia lamblia Kinase, CMGC CK2 0.0103 0.0677 0.225
Plasmodium falciparum NIMA related kinase 2 0.0051 0.013 0.0485
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0092 0.0559 0.2993
Echinococcus granulosus epidermal growth factor receptor 0.0164 0.1319 0.2604
Giardia lamblia Kinase, CMGC CDK 0.0123 0.0884 0.3101
Schistosoma mansoni nAChR subunit 0.0177 0.145 0.2988
Schistosoma mansoni serine/threonine protein kinase 0.0067 0.0296 0.0609
Echinococcus granulosus nAChR subunit 0.0177 0.145 0.2863
Echinococcus multilocularis mitogen activated protein kinase 11 0.0165 0.1331 0.2627
Loa Loa (eye worm) hypothetical protein 0.0177 0.145 0.1449
Onchocerca volvulus 0.0341 0.3169 0.8136
Loa Loa (eye worm) hypothetical protein 0.0082 0.0453 0.0452
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0151 0.118 0.3066
Schistosoma mansoni protein kinase 0.0088 0.0521 0.1074
Brugia malayi Temporarily assigned gene name protein 59 0.0118 0.0837 0.0836
Trypanosoma brucei protein kinase, putative 0.0133 0.0994 0.2789
Brugia malayi map kinase activated protein kinase protein 2 0.0414 0.3934 0.3933
Schistosoma mansoni protein kinase 0.0385 0.363 0.7484
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0277 0.2495 0.4939
Brugia malayi hypothetical protein 0.006 0.0225 0.0224
Echinococcus granulosus mitogen activated protein kinase 3 0.0086 0.0496 0.0969
Brugia malayi Protein kinase domain containing protein 0.0063 0.0254 0.0253
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0177 0.145 0.2988
Brugia malayi Casein kinase II, alpha chain 0.0103 0.0677 0.0676
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.015 0.1171 0.231
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0183 0.1509 0.2982
Echinococcus multilocularis epidermal growth factor receptor 0.0238 0.2088 0.413
Loa Loa (eye worm) hypothetical protein 0.0245 0.2168 0.2167
Leishmania major casein kinase II, putative 0.0103 0.0677 0.2505
Echinococcus multilocularis 0.0067 0.0304 0.0588
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0182 0.1504 0.2971
Trichomonas vaginalis CAMK family protein kinase 0.0283 0.2562 0.7411
Entamoeba histolytica PH domain containing protein kinase, putative 0.0217 0.187 0.4885
Trichomonas vaginalis CK1 family protein kinase 0.0112 0.0772 0.2136
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0458 0.4395 0.8713
Trichomonas vaginalis AGC family protein kinase 0.0151 0.118 0.3338
Schistosoma mansoni serine/threonine protein kinase 0.0117 0.082 0.1691
Echinococcus granulosus serine/threonine protein kinase 0.0217 0.187 0.3697
Brugia malayi Kinase associated domain 1 family protein 0.0065 0.0277 0.0276
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0165 0.1331 0.5104
Brugia malayi excitatory GABA receptor EXP-1A 0.0177 0.145 0.1449
Echinococcus granulosus NDR protein kinase 0.0182 0.1504 0.2971
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0082 0.0453 0.0452
Schistosoma mansoni serine/threonine protein kinase 0.0171 0.1386 0.2857
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0087 0.0506 0.1824
Echinococcus multilocularis casein kinase i 0.0112 0.0772 0.1517
Schistosoma mansoni serine/threonine protein kinase 0.0112 0.0772 0.1591
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0411 0.3895 0.7719
Loa Loa (eye worm) AUR protein kinase 0.0151 0.118 0.1179
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0123 0.0882 0.1737
Trypanosoma cruzi casein kinase, putative 0.0112 0.0772 0.2881
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0118 0.0837 0.2327
Giardia lamblia Kinase, CMGC DYRK 0.0144 0.1108 0.402
Schistosoma mansoni serine/threonine protein kinase 0.0117 0.082 0.1691
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0177 0.145 0.1449
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.016 0.127 0.3604
Echinococcus granulosus protein kinase c iota type 0.0314 0.2885 0.5714
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0132 0.0979 0.3705
Schistosoma mansoni tyrosine kinase 0.0041 0.0032 0.0066
Schistosoma mansoni serine/threonine protein kinase 0.0341 0.3169 0.6533
Entamoeba histolytica PH domain containing protein kinase, putative 0.0043 0.0047 0.0079
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0079 0.0164
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0103 0.0677 0.0676
Schistosoma mansoni ephrin receptor 0.0085 0.0494 0.1018
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0055 0.0174 0.0372
Echinococcus multilocularis serine:threonine protein kinase N2 0.0182 0.1504 0.2971
Schistosoma mansoni serine/threonine protein kinase 0.021 0.1792 0.3694
Echinococcus multilocularis dual specificity protein kinase clk2 0.016 0.127 0.2506
Schistosoma mansoni acetylcholine receptor subunit beta 0.0082 0.0453 0.0934
Toxoplasma gondii NEK kinase 0.0051 0.013 0.0253
Echinococcus granulosus dual specificity protein kinase clk2 0.016 0.127 0.2506
Loa Loa (eye worm) hypothetical protein 0.0177 0.145 0.1449
Entamoeba histolytica protein kinase domain containing protein 0.0126 0.0922 0.2387
Schistosoma mansoni nAChR subunit 0.0177 0.145 0.2988
Onchocerca volvulus 0.008 0.0438 0.1122
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0214 0.1841 0.3639
Schistosoma mansoni titin 0.0046 0.0079 0.0164
Entamoeba histolytica cell division protein kinase 2, putative 0.0123 0.0884 0.2287
Echinococcus granulosus roundabout 2 0.0076 0.0399 0.0776
Plasmodium falciparum cGMP-dependent protein kinase 0.014 0.1059 0.5923
Loa Loa (eye worm) hypothetical protein 0.0095 0.0596 0.0595
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0385 0.363 0.7193
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0126 0.0922 0.0921
Echinococcus multilocularis serine:threonine protein kinase 38 0.0182 0.1504 0.2971
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0086 0.0496 0.1322
Schistosoma mansoni neurotransmitter gated ion channel 0.0082 0.0453 0.0934
Plasmodium falciparum glycogen synthase kinase 3 0.0133 0.0994 0.5539
Loa Loa (eye worm) SRC-1 0.0072 0.0357 0.0356
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0133 0.0994 0.2048
Echinococcus multilocularis Protein kinase C, brain isozyme 0.027 0.242 0.479
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0177 0.145 0.1449
Entamoeba histolytica protein kinase, putative 0.0043 0.0047 0.0079
Trichomonas vaginalis CMGC family protein kinase 0.0123 0.0884 0.2467
Loa Loa (eye worm) protein kinase domain-containing protein 0.0223 0.193 0.1929
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0055 0.0174 0.0502
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0232 0.2029 0.4014
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0177 0.145 0.1449
Echinococcus multilocularis glycine receptor subunit beta 0.0177 0.145 0.2863
Plasmodium falciparum serine/threonine protein kinase 0.0085 0.0489 0.2584
Loa Loa (eye worm) hypothetical protein 0.0044 0.0063 0.0062
Loa Loa (eye worm) hypothetical protein 0.0044 0.0063 0.0062
Onchocerca volvulus 0.0177 0.145 0.372
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0559 0.1507
Schistosoma mansoni serine/threonine protein kinase 0.0414 0.3934 0.811
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0183 0.1509 0.2982
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0246 0.2171 0.4296
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0072 0.0353 0.0685
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0411 0.3896 0.3896
Trichomonas vaginalis CMGC family protein kinase 0.0144 0.1108 0.3125
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0559 0.1507
Echinococcus granulosus dual specificity 0.0144 0.1108 0.2184
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0177 0.145 0.1449
Schistosoma mansoni serine/threonine-protein kinase 0.0217 0.187 0.3854
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0559 0.1507
Brugia malayi cell division control protein 2 homolog 0.0123 0.0884 0.0883
Echinococcus granulosus glycine receptor subunit beta 0.0177 0.145 0.2863
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0121 0.0865 0.0864
Brugia malayi Protein kinase domain containing protein 0.037 0.3473 0.3472
Brugia malayi Temporarily assigned gene name protein 59 0.0137 0.1028 0.1027
Trichomonas vaginalis AGC family protein kinase 0.0141 0.1076 0.3033
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0133 0.0994 0.1957
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0041 0.0032 0.0048
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0085 0.0489 0.1301
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0559 0.1507
Schistosoma mansoni serine/threonine-protein kinase 0.0217 0.187 0.3854
Loa Loa (eye worm) hypothetical protein 0.0074 0.0372 0.0371
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0086 0.0496 0.1368
Echinococcus multilocularis neuroglian 0.0063 0.0254 0.0488
Brugia malayi hypothetical protein 0.0054 0.0162 0.0161
Echinococcus granulosus cGMP dependent protein kinase 0.014 0.1059 0.2087
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0677 0.1857
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0411 0.3895 0.7719
Loa Loa (eye worm) hypothetical protein 0.0082 0.0453 0.0452
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0055 0.0174 0.0173
Trichomonas vaginalis AGC family protein kinase 0.0151 0.118 0.3338
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0177 0.145 0.1449
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0051 0.0135 0.0252
Giardia lamblia Kinase, PLK 0.0283 0.2562 1
Brugia malayi Protein kinase domain 0.0088 0.0521 0.052
Entamoeba histolytica hypothetical protein 0.0402 0.3808 1
Plasmodium vivax tyrosine kinase-like protein, putative 0.0083 0.0466 0.2449
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0095 0.0596 0.0595
Loa Loa (eye worm) hypothetical protein 0.0329 0.3041 0.304
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0559 0.1507
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0141 0.1076 0.3138
Brugia malayi casein kinase I 0.0112 0.0772 0.0771
Trichomonas vaginalis AGC family protein kinase 0.0151 0.118 0.3338
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0086 0.0496 0.1784
Giardia lamblia Kinase, AGC PKA 0.0117 0.082 0.2838
Loa Loa (eye worm) hypothetical protein 0.0095 0.0596 0.0595
Schistosoma mansoni serine/threonine protein kinase 0.0086 0.0496 0.1022
Plasmodium vivax casein kinase 1, putative 0.0112 0.0772 0.4241
Trichomonas vaginalis AGC family protein kinase 0.0367 0.344 1
Brugia malayi Cation transporter family protein 0.0177 0.145 0.1449
Brugia malayi intracellular kinase 0.0133 0.0994 0.0993
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0117 0.082 0.1613
Schistosoma mansoni serine/threonine protein kinase 0.014 0.1059 0.2184
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0072 0.0353 0.0685
Echinococcus multilocularis dual specificity 0.0126 0.0922 0.1816
Echinococcus multilocularis calcium dependent protein kinase 0.0072 0.0351 0.0682
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0171 0.1386 0.1385
Giardia lamblia Aurora kinase 0.0151 0.118 0.4316
Brugia malayi Stress-activated protein kinase jnk-1 0.0277 0.2495 0.2494
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0177 0.145 0.1449
Trypanosoma brucei cdc2-related kinase 3 0.0123 0.0884 0.2467
Schistosoma mansoni hypothetical protein 0.0065 0.0277 0.057
Trypanosoma cruzi cdc2-related kinase 1 0.0123 0.0884 0.3328
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0051 0.013 0.0329
Echinococcus multilocularis insulin receptor 0.0206 0.1753 0.3464
Schistosoma mansoni tyrosine kinase 0.0072 0.0357 0.0735
Trichomonas vaginalis CAMK family protein kinase 0.0131 0.0968 0.2714
Echinococcus granulosus mitogen activated protein kinase 0.0086 0.0496 0.0969
Brugia malayi Immunoglobulin I-set domain containing protein 0.0054 0.0162 0.0161
Echinococcus multilocularis aurora kinase A 0.0151 0.118 0.2327
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.015 0.117 0.3309
Schistosoma mansoni atypical protein kinase C 0.032 0.2953 0.6087
Brugia malayi Protein kinase domain containing protein 0.0201 0.1704 0.1703
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0157 0.1239 0.1238
Schistosoma mansoni serine/threonine protein kinase 0.0271 0.2435 0.5021
Echinococcus granulosus nervana 2 0.0174 0.1422 0.2807
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.037 0.3469 0.3469
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0232 0.2029 0.2029
Brugia malayi Protein kinase domain containing protein 0.0202 0.1714 0.1713
Echinococcus granulosus neuroglian 0.0063 0.0254 0.0488
Plasmodium falciparum protein kinase, putative 0.005 0.0119 0.0417
Brugia malayi serine/threonine protein kinase 6 0.0151 0.118 0.1179
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0209 0.1791 0.3542
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.013 0.0269
Onchocerca volvulus 0.0046 0.0077 0.0194
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0456 0.4374 0.867
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0092 0.0559 0.1507
Onchocerca volvulus 0.0309 0.2835 0.7278
Brugia malayi Protein kinase domain containing protein 0.0094 0.058 0.0579
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0559 0.1507
Echinococcus multilocularis serine:threonine protein kinase 3 0.0269 0.2413 0.4776
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0052 0.0147 0.0275
Loa Loa (eye worm) hypothetical protein 0.0068 0.0308 0.0308
Echinococcus multilocularis titin 0.0046 0.0079 0.0142
Schistosoma mansoni nephrin 0.0065 0.0281 0.0578
Entamoeba histolytica protein kinase, putative 0.0076 0.0395 0.0995
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0092 0.0559 0.1094
Trypanosoma brucei aurora B kinase 0.0151 0.118 0.3338
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0117 0.082 0.2278
Schistosoma mansoni serine/threonine kinase 0.0097 0.0611 0.1259
Plasmodium falciparum calcium-dependent protein kinase 3 0.0104 0.0685 0.3734
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0046 0.0077 0.0136
Brugia malayi serine/threonine-protein kinase plk-2 0.0283 0.2562 0.2561
Echinococcus granulosus ephrin type A receptor 4 A 0.0085 0.0494 0.0964
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0095 0.0596 0.1229
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0123 0.0884 0.0883
Loa Loa (eye worm) hypothetical protein 0.0151 0.1181 0.118
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0194 0.1626 0.3213
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0082 0.0453 0.0883
Trichomonas vaginalis AGC family protein kinase 0.0151 0.118 0.3338
Giardia lamblia Kinase, CMGC CLK 0.016 0.127 0.4688
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0677 0.1857
Entamoeba histolytica protein kinase, putative 0.0151 0.118 0.3066
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0177 0.145 0.1449
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0151 0.118 0.2327
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0104 0.0685 0.3734
Schistosoma mansoni unc-13 (munc13) 0.0046 0.0077 0.0158
Schistosoma mansoni serine/threonine protein kinase 0.0085 0.0489 0.1008
Entamoeba histolytica serine/threonine protein kinase, putative 0.0051 0.013 0.0298
Echinococcus granulosus hypothetical protein 0.0128 0.0936 0.1843
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0227 0.1979 0.1978
Onchocerca volvulus 0.0151 0.1181 0.3031
Echinococcus granulosus tyrosine protein kinase HCK 0.0049 0.0109 0.0201
Plasmodium vivax glycogen synthase kinase 3, putative 0.0133 0.0994 0.5539
Trypanosoma cruzi aurora B kinase, putative 0.0151 0.118 0.4504
Plasmodium vivax serine/threonine protein kinase, putative 0.0085 0.0489 0.2584
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0088 0.0521 0.1019
Brugia malayi MAP kinase sur-1 0.0086 0.0496 0.0495
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0083 0.0471 0.0919
Brugia malayi Cam kinase protein 1 0.0104 0.0685 0.0684
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0208 0.1779 0.3517
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0051 0.0135 0.0278
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0082 0.0453 0.0452
Trichomonas vaginalis STE family protein kinase 0.0088 0.0521 0.1396
Echinococcus multilocularis c src tyrosine kinase 0.0041 0.0032 0.0048
Trypanosoma cruzi polo-like protein kinase, putative 0.0283 0.2562 1
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0118 0.0837 0.1646
Echinococcus multilocularis serine:threonine protein kinase N2 0.0319 0.294 0.5822
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0085 0.0489 0.0488
Schistosoma mansoni protein kinase 0.0151 0.118 0.2432
Trypanosoma brucei polo-like protein kinase 0.0283 0.2562 0.7411
Trichomonas vaginalis AGC family protein kinase 0.0367 0.344 1
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0177 0.145 0.2863
Schistosoma mansoni serine/threonine protein kinase 0.0194 0.1626 0.3352
Schistosoma mansoni tyrosine kinase 0.0041 0.0032 0.0066
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.015 0.1172 0.2312
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0082 0.0453 0.0883
Loa Loa (eye worm) hypothetical protein 0.0076 0.0394 0.0393
Echinococcus granulosus N chimaerin 0.0052 0.0147 0.0275
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0117 0.082 0.1613
Loa Loa (eye worm) casein kinase 0.0191 0.1596 0.1595
Echinococcus granulosus glycine receptor subunit alpha 1 0.0177 0.145 0.2863
Echinococcus granulosus Immunoglobulin 0.0051 0.0135 0.0252
Brugia malayi diacylglycerol kinase 0.0044 0.0063 0.0062
Trypanosoma brucei Serine/threonine-protein kinase NEK16, putative 0.0051 0.013 0.0244
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0057 0.0193 0.0368
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0097 0.0611 0.061
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0072 0.0357 0.0692
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0117 0.082 0.3074
Trichomonas vaginalis AGC family protein kinase 0.0367 0.344 1
Echinococcus multilocularis PAK box P21 Rho binding 0.0065 0.0281 0.0542
Loa Loa (eye worm) hypothetical protein 0.0051 0.0135 0.0134
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0201 0.1704 0.1703
Trichomonas vaginalis CAMK family protein kinase 0.0283 0.2562 0.7411
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.014 0.1059 0.3086
Schistosoma mansoni serine/threonine protein kinase 0.0055 0.0174 0.0358
Loa Loa (eye worm) hypothetical protein 0.0051 0.0137 0.0136
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0208 0.1779 0.3517
Onchocerca volvulus 0.0068 0.0308 0.079
Onchocerca volvulus Putative nachr subunit 0.0411 0.3895 1
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0083 0.0466 0.2449
Loa Loa (eye worm) hypothetical protein 0.0177 0.145 0.1449
Loa Loa (eye worm) hypothetical protein 0.0056 0.0187 0.0186
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.013 0.0244
Echinococcus granulosus tyrosine protein kinase Fyn 0.0072 0.0357 0.0692
Trypanosoma cruzi cdc2-related kinase 3 0.0123 0.0884 0.3328
Plasmodium falciparum calcium-dependent protein kinase 4 0.0104 0.0685 0.3734
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0177 0.145 0.1449
Brugia malayi probable protein kinase 0.0277 0.2502 0.2501
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0182 0.1504 0.2971
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0086 0.0496 0.1784
Entamoeba histolytica protein kinase, putative 0.0065 0.0281 0.0695
Brugia malayi Protein kinase domain containing protein 0.0182 0.1504 0.1503
Entamoeba histolytica diacylglycerol kinase, putative 0.0044 0.0063 0.0119
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.0559 0.1152
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.016 0.127 0.4863
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0052 0.0147 0.0302
Leishmania major serine/threonine-protein kinase, putative 0.0051 0.013 0.0329
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0072 0.0357 0.0692
Loa Loa (eye worm) hypothetical protein 0.0082 0.0453 0.0452
Schistosoma mansoni protein kinase 0.0201 0.1704 0.3513
Entamoeba histolytica protein kinase domain containing protein 0.0151 0.118 0.3066
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0611 0.1259
Entamoeba histolytica PH domain containing protein kinase, putative 0.0043 0.0047 0.0079
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0206 0.1756 1
Loa Loa (eye worm) hypothetical protein 0.0177 0.145 0.1449
Onchocerca volvulus Serine\/threonine kinase homolog 0.0171 0.1386 0.3556
Echinococcus multilocularis tyrosine protein kinase Srms 0.0057 0.0193 0.0368
Entamoeba histolytica protein kinase, putative 0.0133 0.0994 0.2575
Loa Loa (eye worm) RasGEF domain-containing protein 0.0044 0.0063 0.0062
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0072 0.0357 0.0692
Schistosoma mansoni serine/threonine protein kinase 0.0232 0.2029 0.4184
Loa Loa (eye worm) LGC-31 protein 0.0177 0.145 0.1449
Loa Loa (eye worm) hypothetical protein 0.0054 0.0162 0.0161
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.005 0.0119 0.021
Echinococcus multilocularis cyclin dependent kinase 1 0.0123 0.0884 0.174
Onchocerca volvulus Tyrosine kinase homolog 0.036 0.3362 0.8631
Echinococcus granulosus fibroblast growth factor receptor 4 0.0123 0.0882 0.1737
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0182 0.1504 0.1503
Brugia malayi Cation transporter family protein 0.0177 0.145 0.1449
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0411 0.3895 0.7719
Loa Loa (eye worm) hypothetical protein 0.0126 0.0917 0.0916
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0072 0.0353 0.0685
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.0559 0.1152
Trypanosoma cruzi casein kinase, putative 0.0112 0.0772 0.2881
Brugia malayi Protein kinase domain containing protein 0.021 0.1792 0.1791
Echinococcus multilocularis hypothetical protein 0.0065 0.0277 0.0533
Toxoplasma gondii AGC kinase 0.0117 0.082 0.2357
Schistosoma mansoni protein kinase C 0.0046 0.0077 0.0158
Brugia malayi Protein kinase c protein 2 0.012 0.085 0.0849
Schistosoma mansoni rap gtpase-activating protein 0.0118 0.0837 0.1726
Brugia malayi P38 map kinase family protein 2 0.0165 0.1331 0.133
Echinococcus granulosus tyrosine kinase 0.0057 0.0193 0.0368
Echinococcus multilocularis roundabout 2 0.0076 0.0399 0.0776
Echinococcus granulosus myotubularin protein 13 0.0055 0.0177 0.0335
Echinococcus granulosus c-Jun N-terminal kinases 0.0277 0.2495 0.4939
Echinococcus multilocularis dual specificity 0.0144 0.1108 0.2184
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0052 0.0147 0.0275
Trichomonas vaginalis CMGC family protein kinase 0.0144 0.1108 0.3125
Loa Loa (eye worm) hypothetical protein 0.0177 0.145 0.1449
Echinococcus multilocularis casein kinase I alpha 0.0112 0.0772 0.1517
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0072 0.0357 0.0692
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0194 0.1626 0.3213
Schistosoma mansoni tyrosine kinase 0.0206 0.1753 0.3613
Schistosoma mansoni tyrosine kinase 0.0147 0.1134 0.2338
Schistosoma mansoni kinase 0.0303 0.2766 0.5702
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0559 0.1507
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0187 0.0411
Schistosoma mansoni ste20-related kinase 0.0214 0.184 0.3794
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0123 0.0882 0.1737
Echinococcus granulosus casein kinase I delta 0.0112 0.0772 0.1517
Onchocerca volvulus 0.0331 0.3058 0.7849
Loa Loa (eye worm) raf kinase 0.0044 0.0063 0.0062
Echinococcus granulosus Glutaredoxin protein 5 0.0174 0.1422 0.2807
Plasmodium falciparum casein kinase 1 0.0112 0.0772 0.4241
Loa Loa (eye worm) hypothetical protein 0.0177 0.145 0.1449
Brugia malayi Cation transporter family protein 0.0177 0.145 0.1449
Plasmodium falciparum calcium-dependent protein kinase 2 0.0104 0.0685 0.3734
Brugia malayi Serine/threonine-protein kinase SULU 0.0232 0.2029 0.2029
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0126 0.0922 0.348
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0117 0.082 0.1613
Trypanosoma brucei SNF1-related protein kinases, putative 0.0092 0.0559 0.1507
Brugia malayi Ras association domain family 1 isoform A 0.0044 0.0063 0.0062
Plasmodium falciparum protein kinase 5 0.0123 0.0884 0.4899
Plasmodium falciparum serine/threonine protein kinase KIN 0.0092 0.0559 0.2993
Entamoeba histolytica casein kinase 1, putative 0.0112 0.0772 0.199
Loa Loa (eye worm) hypothetical protein 0.0051 0.0135 0.0134
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0283 0.2562 1
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0385 0.363 0.363
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0248 0.0511
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0177 0.145 0.1449
Schistosoma mansoni protein kinase 0.0456 0.4374 0.9017
Echinococcus granulosus dual specificity 0.0144 0.1108 0.2184
Entamoeba histolytica protein kinase, putative 0.0126 0.0922 0.2387
Loa Loa (eye worm) AUR protein kinase 0.0151 0.118 0.1179
Trypanosoma brucei protein kinase, putative 0.005 0.0119 0.021
Trypanosoma cruzi polo-like protein kinase, putative 0.0283 0.2562 1
Toxoplasma gondii AGC kinase 0.0356 0.3326 1
Trichomonas vaginalis CAMK family protein kinase 0.0283 0.2562 0.7411
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0212 0.1813 0.3584
Entamoeba histolytica protein kinase, putative 0.0367 0.344 0.9028
Trichomonas vaginalis AGC family protein kinase 0.0193 0.1618 0.4629
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0082 0.0453 0.0883
Entamoeba histolytica protein kinase, putative 0.0083 0.0471 0.1196
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0217 0.187 0.7247
Brugia malayi Protein kinase domain containing protein 0.0126 0.0922 0.0921
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0356 0.3326 0.3325
Schistosoma mansoni neurotransmitter gated ion channel 0.0082 0.0453 0.0934
Loa Loa (eye worm) hypothetical protein 0.0191 0.16 0.1599

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 5.5 uM Inhibition of mouse J774 cell survival by alamar blue viability assay ChEMBL. 17149877
IC50 (functional) = 5.5 uM Inhibition of mouse J774 cell survival by alamar blue viability assay ChEMBL. 17149877

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Mus musculus ChEMBL23 17149877

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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