Detailed information for compound 460810

Basic information

Technical information
  • TDR Targets ID: 460810
  • Name: ethyl (2E,4E)-hexa-2,4-dienoate
  • MW: 140.18 | Formula: C8H12O2
  • H donors: 0 H acceptors: 1 LogP: 1.95 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)/C=C/C=C/C
  • InChi: 1S/C8H12O2/c1-3-5-6-7-8(9)10-4-2/h3,5-7H,4H2,1-2H3/b5-3+,7-6+
  • InChiKey: OZZYKXXGCOLLLO-TWTPFVCWSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2E,4E)-hexa-2,4-dienoic acid ethyl ester
  • Ethyl hexa-2,4-dienoate
  • hexa-2,4-dienoic acid ethyl ester
  • 91660-95-6
  • 2396-84-1
  • 5941-48-0
  • ZINC01648290
  • W245909_ALDRICH
  • 2,4-Hexadienoic acid, ethyl ester (9CI)
  • 2,4-Hexadienoic acid, ethyl ester, (2E,4E)-
  • 2,4-Hexadienoic acid, ethyl ester, (E,E)-
  • 2,4-Hexadienoic acid, ethyl ester, (E,E)- (9CI)
  • AI3-11732
  • EINECS 219-258-2
  • Ethyl (E,E)-2,4-hexadienoate
  • Ethyl 2,4-hexadienoate, (E,E)-
  • FEMA No. 2459
  • NSC 8874
  • 2,4-Hexadienoic acid, ethyl ester
  • Ethyl 2,4-hexadienoate
  • Ethyl sorbate
  • NSC8874
  • Sorbic acid, ethyl ester
  • InChI=1/C8H12O2/c1-3-5-6-7-8(9)10-4-2/h3,5-7H,4H2,1-2H3/b5-3+,7-6
  • 2,4-Hexadienoic acid, ethyl ester, (E,E)-)
  • Ethyl (2E,4E)-2,4-hexadienoate
  • 177687_ALDRICH
  • 85525_FLUKA
  • Ethyl trans,trans-2,4-hexadienoate

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans hypothetical protein 0.0164 0.0941 0.2542
Echinococcus granulosus histone deacetylase 6 0.0092 0.0474 0.0465
Trypanosoma cruzi PAB1-binding protein , putative 0.0033 0.0092 0.0164
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0025 0.0043 0.0043
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.0605 0.2986
Loa Loa (eye worm) histone deacetylase 7A 0.0092 0.0474 0.047
Schistosoma mansoni thyroid hormone receptor 0.0226 0.1343 0.1318
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0096 0.0503 0.0475
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0027 0.0034
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0029 0.0068 0.0146
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0492 0.0464
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0036 0.0111 0.0082
Schistosoma mansoni myelin transcription factor 1 myt1 0.0099 0.0519 0.0491
Echinococcus multilocularis neuropeptides capa receptor 0.0036 0.0111 0.0101
Brugia malayi histone deacetylase 11 0.0092 0.0474 0.0474
Loa Loa (eye worm) 6-phosphofructokinase 0.0112 0.0605 0.06
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0045 0.0174 0.0164
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0111 0.0082
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0029 0.0068 0.021
Loa Loa (eye worm) hypothetical protein 0.0096 0.0503 0.0499
Leishmania major histone deacetylase, putative 0.0092 0.0474 0.118
Brugia malayi nuclear receptor NHR-88 0.0096 0.0503 0.0503
Onchocerca volvulus 0.0036 0.0111 0.0097
Plasmodium vivax histone deacetylase, putative 0.0092 0.0474 0.231
Echinococcus multilocularis lamin dm0 0.0042 0.0149 0.0139
Echinococcus granulosus gamma secretase subunit aph 1 0.0118 0.0641 0.0632
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0036 0.011 0.024
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0025 0.0043 0.0043
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0068 0.0322 0.0312
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0355 0.0326
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0096 0.0503 0.0494
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0068 0.0322 0.0312
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Loa Loa (eye worm) hypothetical protein 0.0266 0.1598 0.1594
Entamoeba histolytica serine/threonine protein kinase, putative 0.0092 0.0474 0.2308
Leishmania major DNA polymerase eta, putative 0.0061 0.0275 0.0655
Mycobacterium ulcerans aminopeptidase N PepN 0.0024 0.0035 0.0057
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0036 0.0111 0.0111
Schistosoma mansoni tyrosine kinase 0.0025 0.0038 0.0009
Mycobacterium ulcerans 6-phosphofructokinase 0.0112 0.0605 0.162
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0023 0.0029 0.0024
Plasmodium falciparum glutathione reductase 0.0073 0.0352 0.1677
Toxoplasma gondii eukaryotic initiation factor-4E, putative 0.0036 0.011 0.0429
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0185 0.1076 0.2912
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0262 0.0678
Brugia malayi polk-prov protein 0.0038 0.0127 0.0127
Entamoeba histolytica aminopeptidase, putative 0.0068 0.0322 0.1524
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0233 0.1387 0.1379
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0024 0.0035 0.0016
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0092 0.0474 0.0464
Plasmodium falciparum M1-family alanyl aminopeptidase, putative 0.0024 0.0035 0.0043
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.005
Echinococcus granulosus L aminoadipate semialdehyde 0.0081 0.0403 0.0393
Loa Loa (eye worm) hypothetical protein 0.0045 0.0174 0.0169
Schistosoma mansoni peroxidasin 0.0027 0.0055 0.0026
Trypanosoma brucei aminopeptidase, putative 0.0024 0.0035 0.0022
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0024
Loa Loa (eye worm) MBCTL1 0.0099 0.0519 0.0514
Leishmania major extracellular receptor, putative 0.0023 0.0029 0.0006
Schistosoma mansoni zinc finger protein 0.0039 0.0134 0.0105
Schistosoma mansoni neuropeptide receptor 0.0036 0.0111 0.0082
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0174 0.0446
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0102 0.0538 0.1344
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0283 0.0669
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0102 0.0538 0.0529
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0029 0.0068 0.0107
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.005
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.0225 0.0517
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0038 0.0123 0.0114
Echinococcus granulosus polycomb protein SCMH1 0.0087 0.0441 0.0432
Giardia lamblia DINP protein human, muc B family 0.0042 0.0149 0.0551
Schistosoma mansoni nuclear hormone receptor 0.0045 0.0174 0.0145
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0266 0.1598 0.8114
Trypanosoma cruzi Aph-1 protein, putative 0.0046 0.0177 0.0389
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0036 0.0111 0.0101
Loa Loa (eye worm) hypothetical protein 0.005 0.0202 0.0197
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0133 0.0742 0.0733
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Echinococcus granulosus neuropeptide FF receptor 2 0.0036 0.0111 0.0101
Loa Loa (eye worm) histone deacetylase 1 0.0322 0.1963 0.1959
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0266 0.1598 0.159
Echinococcus multilocularis thyroid hormone receptor alpha 0.0226 0.1343 0.1335
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0045 0.0171 0.0162
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0283 0.0675
Plasmodium vivax SUMO-activating enzyme subunit 2, putative 0.0033 0.0092 0.0334
Echinococcus granulosus intermediate filament protein 0.0042 0.0149 0.0139
Loa Loa (eye worm) peptidase family M1 containing protein 0.0188 0.1095 0.109
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0266 0.1598 0.1598
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0029 0.0068 0.021
Wolbachia endosymbiont of Brugia malayi N-acetylglucosamine-1-phosphate uridyltransferase 0.0585 0.366 1
Schistosoma mansoni lamin 0.0042 0.0149 0.012
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0157 0.0336
Echinococcus multilocularis sodium and chloride dependent glycine 0.0266 0.1598 0.159
Echinococcus granulosus sodium and chloride dependent glycine 0.0266 0.1598 0.159
Echinococcus granulosus 7tm_1 domain containing protein 0.0036 0.0111 0.0101
Echinococcus multilocularis acetylcholinesterase 0.007 0.0332 0.0323
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0063 0.0287 0.0747
Trichomonas vaginalis DNA helicase recq, putative 0.0053 0.0225 0.061
Trypanosoma cruzi histone deacetylase, putative 0.0092 0.0474 0.1174
Brugia malayi phosphofructokinase 0.0112 0.0605 0.0605
Trypanosoma cruzi DNA polymerase eta, putative 0.0037 0.012 0.0239
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.013 0.0121
Brugia malayi hypothetical protein 0.0033 0.0092 0.0092
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0049 0.0199 0.089
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0025 0.0038 0.0024
Echinococcus granulosus receptor type guanylyl cyclase 0.0025 0.0038 0.0029
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0096 0.0503 0.0503
Brugia malayi nuclear hormone receptor 0.0096 0.0503 0.0503
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0036 0.0111 0.0101
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0063 0.0287 0.0277
Mycobacterium tuberculosis Conserved hypothetical protein 0.0107 0.0573 0.1532
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0262 0.0233
Loa Loa (eye worm) hypothetical protein 0.0044 0.0167 0.0162
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0062 0.0283 0.0795
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0283 0.0669
Loa Loa (eye worm) hypothetical protein 0.0051 0.0209 0.0205
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0031
Schistosoma mansoni ap endonuclease 0.0029 0.0068 0.0038
Onchocerca volvulus 0.0232 0.1381 0.1369
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0096 0.0503 0.0503
Echinococcus granulosus lamin dm0 0.0042 0.0149 0.0139
Schistosoma mansoni hypothetical protein 0.0036 0.0111 0.0082
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0322 0.1963 0.6201
Echinococcus multilocularis g protein coupled receptor 0.0036 0.0111 0.0101
Leishmania major ATP-dependent phosphofructokinase 0.0112 0.0605 0.1525
Trypanosoma cruzi aminopeptidase, putative 0.0068 0.0322 0.0772
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0034 0.01 0.0095
Echinococcus granulosus glutamate receptor 4 0.0054 0.0227 0.0217
Brugia malayi steroid hormone receptor 0.0096 0.0503 0.0503
Mycobacterium ulcerans bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 0.0585 0.366 1
Brugia malayi AKH receptor 0.0036 0.0111 0.0111
Loa Loa (eye worm) histone deacetylase 0.0092 0.0474 0.047
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0096 0.0503 0.0503
Trypanosoma cruzi polo-like protein kinase, putative 0.0092 0.0474 0.1173
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0038 0.0128 0.0311
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0266 0.1598 0.1573
Echinococcus granulosus tar DNA binding protein 0.0073 0.0355 0.0345
Loa Loa (eye worm) hypothetical protein 0.1565 1 1
Brugia malayi Animal haem peroxidase family protein 0.0027 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0045 0.0174 0.0169
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0111 0.0101
Echinococcus granulosus sodium and chloride dependent glycine 0.0266 0.1598 0.159
Echinococcus multilocularis neuropeptide Y receptor 0.0036 0.0111 0.0101
Echinococcus granulosus acetylcholinesterase 0.007 0.0332 0.0323
Brugia malayi histone deacetylase 1 (HD1) 0.0322 0.1963 0.1963
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0024
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0036 0.0111 0.0082
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0266 0.1598 0.1598
Schistosoma mansoni nuclear receptor 0.0045 0.0174 0.0145
Loa Loa (eye worm) hypothetical protein 0.0096 0.0503 0.0499
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Leishmania major C-8 sterol isomerase-like protein 0.0609 0.3817 1
Loa Loa (eye worm) hypothetical protein 0.0091 0.0469 0.0465
Onchocerca volvulus 0.0068 0.0322 0.0308
Brugia malayi Pre-SET motif family protein 0.0064 0.0291 0.0291
Echinococcus multilocularis survival motor neuron protein 1 0.023 0.1366 0.1358
Onchocerca volvulus 0.0036 0.0111 0.0097
Schistosoma mansoni glutamate receptor NMDA 0.0122 0.0667 0.064
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0036 0.0111 0.0101
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0036 0.0111 0.0111
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0111 0.0101
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0444 0.2748 0.2744
Trichomonas vaginalis DNA polymerase eta, putative 0.0062 0.0283 0.0795
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0111 0.0101
Schistosoma mansoni inositol monophosphatase 0.0043 0.0157 0.0128
Plasmodium falciparum M1-family alanyl aminopeptidase 0.0024 0.0035 0.0043
Echinococcus multilocularis transcription factor Dp 1 0.0059 0.0261 0.0252
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Loa Loa (eye worm) hypothetical protein 0.0045 0.0174 0.0169
Brugia malayi Dopamine receptor 0.0036 0.0111 0.0111
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.013 0.0121
Loa Loa (eye worm) histone deacetylase 11 0.0092 0.0474 0.047
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0034 0.01 0.009
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0158 0.0902 0.0875
Echinococcus multilocularis polycomb protein SCMH1 0.0087 0.0441 0.0432
Loa Loa (eye worm) hypothetical protein 0.0078 0.0383 0.0378
Schistosoma mansoni biogenic amine (5HT) receptor 0.0036 0.0111 0.0082
Brugia malayi hypothetical protein 0.0036 0.0111 0.0111
Brugia malayi hypothetical protein 0.0068 0.0322 0.0322
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0036 0.0111 0.0101
Brugia malayi Animal haem peroxidase family protein 0.0027 0.0055 0.0055
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0266 0.1598 0.159
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Mycobacterium ulcerans molybdopterin-guanine dinucleotide biosynthesis protein A 0.0107 0.0573 0.1532
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0096 0.0503 0.0494
Schistosoma mansoni lamin 0.0042 0.0149 0.012
Loa Loa (eye worm) hypothetical protein 0.0091 0.0469 0.0465
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0045 0.0174 0.0164
Onchocerca volvulus 0.0042 0.0149 0.0135
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0068 0.0322 0.0922
Echinococcus granulosus G protein coupled receptor 139 0.0036 0.0111 0.0101
Mycobacterium tuberculosis Conserved hypothetical protein 0.0164 0.0941 0.2542
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Onchocerca volvulus 0.0036 0.0111 0.0097
Loa Loa (eye worm) hypothetical protein 0.0266 0.1598 0.1594
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0024
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0025 0.0043 0.0037
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0096 0.0503 0.0503
Loa Loa (eye worm) hypothetical protein 0.0054 0.0227 0.0222
Schistosoma mansoni sodium-dependent amino acid transporter 0.0266 0.1598 0.1573
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0079 0.0391 0.0391
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0079 0.0138
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0312 0.1895 0.4928
Loa Loa (eye worm) hypothetical protein 0.0034 0.01 0.0095
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0025 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0044 0.0167 0.0162
Loa Loa (eye worm) RGC/RGC protein kinase 0.0025 0.0038 0.0034
Echinococcus granulosus tm gpcr rhodopsin 0.0036 0.0111 0.0101
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0061 0.0276 0.0267
Loa Loa (eye worm) hypothetical protein 0.002 0.001 0.0005
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0185 0.1076 0.2912
Schistosoma mansoni histone deacetylase 4 5 0.0092 0.0474 0.0446
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0068 0.0322 0.0312
Brugia malayi Tachykinin-like peptides receptor 99D 0.0036 0.0111 0.0111
Schistosoma mansoni histone deacetylase 0.0322 0.1963 0.1939
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0025 0.0043 0.0079
Onchocerca volvulus 0.0045 0.0174 0.016
Echinococcus multilocularis glutamate receptor 4 0.0054 0.0227 0.0217
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0102 0.0538 0.0529
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0023 0.0029 0.0024
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0151 0.0854 0.0845
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0043 0.0157 0.039
Onchocerca volvulus 0.0023 0.0029 0.0015
Schistosoma mansoni biogenic amine receptor 0.0036 0.0111 0.0082
Loa Loa (eye worm) TATA binding protein associated factor 0.0024 0.0035 0.0031
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0112 0.0605 0.162
Loa Loa (eye worm) hypothetical protein 0.0081 0.0405 0.0401
Echinococcus multilocularis neuropeptide receptor A26 0.0271 0.1631 0.1623
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0251 0.1506 0.1498
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.013 0.0101
Brugia malayi hypothetical protein 0.0051 0.0209 0.0209
Loa Loa (eye worm) hypothetical protein 0.0087 0.0441 0.0436
Trichomonas vaginalis set domain proteins, putative 0.0505 0.3144 1
Echinococcus multilocularis dro:myosuppressin receptor 0.0036 0.0111 0.0101
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0038 0.0128 0.0311
Schistosoma mansoni intermediate filament proteins 0.0042 0.0149 0.012
Plasmodium vivax histone deacetylase 1, putative 0.0322 0.1963 1
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0025 0.0043 0.0043
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0025 0.0043 0.0037
Leishmania major puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0024 0.0035 0.0022
Echinococcus granulosus lamin 0.0042 0.0149 0.0139
Schistosoma mansoni RAR-like nuclear receptor 0.0096 0.0503 0.0475
Brugia malayi hypothetical protein 0.0036 0.0111 0.0111
Schistosoma mansoni glutamate receptor AMPA 0.0122 0.0667 0.064
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0127 0.0265
Loa Loa (eye worm) phosphofructokinase 0.0112 0.0605 0.06
Onchocerca volvulus Serine\/threonine kinase homolog 0.0092 0.0474 0.046
Echinococcus granulosus serotonin transporter 0.1565 1 1
Echinococcus multilocularis histone deacetylase 1 0.0322 0.1963 0.1955
Echinococcus multilocularis histone deacetylase 6 0.0092 0.0474 0.0465
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0063 0.0287 0.0277
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0266 0.1598 0.1598
Brugia malayi RE15519p 0.0036 0.0111 0.0111
Trypanosoma brucei histone deacetylase 3 0.0092 0.0474 0.118
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0027 0.0034
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0036 0.0111 0.0082
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0041 0.0145 0.0135
Loa Loa (eye worm) hypothetical protein 0.0045 0.0174 0.0169
Schistosoma mansoni alpha-1 adrenergic receptor 0.0036 0.0111 0.0082
Trichomonas vaginalis mercuric reductase, putative 0.0025 0.0043 0.0026
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0068 0.0322 0.0293
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0096 0.0503 0.0494
Echinococcus granulosus histone lysine methyltransferase setb 0.0095 0.0492 0.0483
Schistosoma mansoni sumo-1-activating enzyme E1a 0.005 0.0202 0.0173
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0036 0.0111 0.0082
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0096 0.0503 0.0503
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0099 0.0519 0.0509
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0076 0.0253
Echinococcus multilocularis gamma secretase subunit aph 1 0.0118 0.0641 0.0632
Giardia lamblia Histone deacetylase 0.0322 0.1963 1
Echinococcus multilocularis g protein coupled receptor 0.0036 0.0111 0.0101
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0063 0.0287 0.0747
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0111 0.0082
Toxoplasma gondii aminopeptidase N protein 0.0024 0.0035 0.0043
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0198 0.1157 0.1149
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0036 0.0111 0.0082
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0025 0.0043 0.0037
Trypanosoma cruzi ISWI complex protein 0.0028 0.006 0.0081
Echinococcus granulosus dna polymerase kappa 0.0062 0.0283 0.0273
Echinococcus multilocularis geminin 0.0261 0.157 0.1562
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0199 0.1163 0.1155
Onchocerca volvulus Neuropeptide F receptor homolog 0.0036 0.0111 0.0097
Echinococcus granulosus FTZ F1 alpha 0.0096 0.0503 0.0494
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0044 0.0167 0.0157
Echinococcus granulosus allatostatin A receptor 0.0036 0.0111 0.0101
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0199 0.1163 0.1155
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0163 0.0354
Plasmodium falciparum transporter, putative 0.0266 0.1598 0.8114
Trypanosoma brucei DNA polymerase IV, putative 0.0062 0.0283 0.0675
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0036 0.011 0.0429
Schistosoma mansoni amine GPCR 0.0036 0.0111 0.0082
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0043 0.0157 0.067
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0076 0.013
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0032 0.0087 0.031
Echinococcus granulosus somatostatin receptor 0.0036 0.0111 0.0101
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0027 0.0034
Brugia malayi translation initiation factor 4E 0.0036 0.011 0.011
Plasmodium vivax histone deacetylase, putative 0.0092 0.0474 0.231
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0043 0.0157 0.039
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.005
Echinococcus multilocularis histone deacetylase 0.0092 0.0474 0.0465
Echinococcus granulosus aminopeptidase N 0.0232 0.1381 0.1373
Brugia malayi hypothetical protein 0.0036 0.0111 0.0111
Echinococcus granulosus SAM and MBT domain containing protein 0.0087 0.0441 0.0432
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0036 0.0111 0.0101
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0036 0.0111 0.0106
Brugia malayi sulfakinin receptor protein 0.0036 0.0111 0.0111
Trichomonas vaginalis DNA helicase recq1, putative 0.0053 0.0225 0.061
Loa Loa (eye worm) ThiF family protein 0.0033 0.0092 0.0087
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0051 0.0209 0.018
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0076 0.013
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0045 0.0174 0.0164
Schistosoma mansoni nuclear hormone receptor 0.0045 0.0174 0.0145
Mycobacterium tuberculosis Conserved protein 0.0138 0.077 0.2073
Brugia malayi GnHR receptor homolog 0.0036 0.0111 0.0111
Trichomonas vaginalis histone deacetylase, putative 0.0322 0.1963 0.6201
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0096 0.0503 0.0499
Trichomonas vaginalis inositol monophosphatase, putative 0.0043 0.0157 0.039
Brugia malayi Probable ATP-dependent helicase DHX35 0.0021 0.0013 0.0013
Schistosoma mansoni DNA helicase recq1 0.0034 0.01 0.0071
Brugia malayi G-protein coupled receptor 0.0036 0.0111 0.0111
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0266 0.1598 0.1573
Trypanosoma brucei ISWI complex protein 0.0028 0.006 0.0087
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0076 0.0253
Schistosoma mansoni histone deacetylase 4 5 0.0092 0.0474 0.0446
Brugia malayi Animal haem peroxidase family protein 0.0027 0.0055 0.0055
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0096 0.0503 0.0475
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0233 0.1387 0.1379
Brugia malayi hypothetical protein 0.0023 0.0029 0.0029
Schistosoma mansoni aminopeptidase A (M01 family) 0.0024 0.0035 0.0006
Mycobacterium tuberculosis Conserved hypothetical protein 0.0138 0.077 0.2073
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0025 0.0043 0.0043
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0036 0.0111 0.0106
Schistosoma mansoni hypothetical protein 0.0038 0.0123 0.0094
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0068 0.0322 0.0778
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0096 0.0503 0.0499
Echinococcus granulosus g protein coupled receptor 0.0036 0.0111 0.0101
Echinococcus granulosus glutamate receptor 1 0.0054 0.0227 0.0217
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.0111 0.0101
Trypanosoma brucei Aminopeptidase M1, putative 0.0068 0.0322 0.0778
Schistosoma mansoni bromodomain containing protein 0.0119 0.0648 0.062
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0474 0.141
Trypanosoma cruzi histone deacetylase, putative 0.0092 0.0474 0.1174
Schistosoma mansoni coup transcription factor 0.0096 0.0503 0.0475
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0096 0.0503 0.0499
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0036 0.0111 0.0101
Brugia malayi Nuclear hormone receptor-like 1 0.0051 0.0209 0.0209
Echinococcus granulosus tyrosine kinase 0.0025 0.0038 0.0029
Schistosoma mansoni hypothetical protein 0.0036 0.0111 0.0082
Loa Loa (eye worm) hypothetical protein 0.0051 0.0209 0.0205
Loa Loa (eye worm) hypothetical protein 0.1565 1 1
Leishmania major ubiquitin-activating enzyme-like protein 0.0033 0.0092 0.017
Echinococcus multilocularis glutamate receptor 2 0.0153 0.0872 0.0863
Echinococcus multilocularis fmrfamide receptor 0.0036 0.0111 0.0101
Loa Loa (eye worm) hypothetical protein 0.0038 0.0127 0.0122
Brugia malayi hypothetical protein 0.0036 0.0111 0.0111
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0266 0.1598 0.8114
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0024
Schistosoma mansoni methyl-cpg binding protein mbd 0.0031 0.0081 0.0051
Brugia malayi G protein-coupled receptor 0.0036 0.0111 0.0111
Trypanosoma cruzi ubiquitin-activating enzyme, putative 0.0033 0.0092 0.0164
Schistosoma mansoni eukaryotic translation initiation factor 4e 0.0036 0.011 0.0081
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0035 0.0105 0.01
Brugia malayi hypothetical protein 0.0062 0.0282 0.0282
Echinococcus multilocularis histone deacetylase 7 0.0092 0.0474 0.0465
Brugia malayi hypothetical protein 0.0036 0.0111 0.0111
Echinococcus multilocularis FTZ F1 alpha 0.0096 0.0503 0.0494
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0348 0.2129 0.2121
Echinococcus granulosus biogenic amine 5HT receptor 0.0036 0.0111 0.0101
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Echinococcus multilocularis glutamate receptor 2 0.0199 0.1163 0.1155
Loa Loa (eye worm) RNA binding protein 0.0073 0.0355 0.035
Loa Loa (eye worm) hypothetical protein 0.0045 0.0174 0.0169
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0133 0.0742 0.0733
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0068 0.0322 0.0772
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.005
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0266 0.1598 0.159
Loa Loa (eye worm) solute carrier family 6 member 4 0.1565 1 1
Onchocerca volvulus Peroxidasin homolog 0.0027 0.0055 0.0041
Schistosoma mansoni blooms syndrome DNA helicase 0.0036 0.0113 0.0084
Schistosoma mansoni sex comb on midleg homolog 0.0087 0.0441 0.0413
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0322 0.1963 0.6201
Loa Loa (eye worm) hypothetical protein 0.0457 0.2835 0.2831
Echinococcus granulosus nuclear receptor nhr 48 0.0045 0.0174 0.0164
Loa Loa (eye worm) bromodomain containing protein 0.0036 0.0111 0.0107
Echinococcus granulosus neuropeptide Y receptor 0.0036 0.0111 0.0101
Echinococcus multilocularis zinc finger protein 0.0039 0.0134 0.0124
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0158 0.0902 0.0875
Brugia malayi hypothetical protein 0.0036 0.0111 0.0111
Echinococcus multilocularis aminopeptidase N 0.0232 0.1381 0.1373
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0355 0.0326
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0266 0.1598 0.1573
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.005
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0096 0.0503 0.0475
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0045 0.0174 0.0145
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0025 0.0043 0.0045
Brugia malayi Nuclear hormone receptor-like 1 0.0051 0.0209 0.0209
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0022 0.0024 0.0019
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0036 0.0111 0.0111
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0063 0.0287 0.0747
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0157 0.0336
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.0209 0.0209
Echinococcus multilocularis bloom syndrome protein 0.0053 0.0225 0.0215
Echinococcus granulosus metabotropic glutamate receptor 5 0.0023 0.0029 0.002
Echinococcus multilocularis glutamate receptor 2 0.0175 0.1014 0.1005
Trypanosoma cruzi DNA polymerase eta, putative 0.0061 0.0275 0.0649
Onchocerca volvulus 0.0025 0.0038 0.0024
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0034 0.01 0.0377
Brugia malayi orphan nuclear receptor NR2E1 0.0045 0.0174 0.0174
Loa Loa (eye worm) hypothetical protein 0.0045 0.0174 0.0169
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0036 0.011 0.024
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0348 0.2129 0.2121
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0322 0.1963 0.6201
Schistosoma mansoni lozenge 0.0057 0.0251 0.0222
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0233 0.1387 0.1379
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.007 0.0332 0.0304
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0266 0.1598 0.159
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.013 0.072 0.0711
Onchocerca volvulus 0.1565 1 1
Schistosoma mansoni neuropeptide f receptor 76f 0.0036 0.0111 0.0082
Echinococcus granulosus neuropeptide receptor 0.0036 0.0111 0.0101
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0048 0.0192 0.0853
Brugia malayi nuclear hormone receptor 0.0045 0.0174 0.0174
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0044 0.0167 0.0362
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0087 0.0441 0.0413
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Brugia malayi hypothetical protein 0.0051 0.0209 0.0209
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0033 0.0091 0.0332
Brugia malayi Peptidase family M1 containing protein 0.0232 0.1381 0.1381
Brugia malayi Bloom's syndrome protein homolog 0.0053 0.0225 0.0225
Brugia malayi hypothetical protein 0.0045 0.0174 0.0174
Loa Loa (eye worm) hypothetical protein 0.0045 0.0174 0.0169
Brugia malayi hypothetical protein 0.023 0.1366 0.1366
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0043 0.0157 0.067
Echinococcus granulosus biogenic amine 5HT receptor 0.0091 0.0469 0.046
Echinococcus multilocularis serotonin transporter 0.1565 1 1
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0096 0.0503 0.049
Echinococcus multilocularis carboxylesterase 5A 0.007 0.0332 0.0323
Entamoeba histolytica histone deacetylase, putative 0.0322 0.1963 1
Echinococcus granulosus 7TM GPCR rhodopsin 0.0036 0.0111 0.0101
Plasmodium falciparum histone deacetylase 1 0.0322 0.1963 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0096 0.0503 0.0494
Loa Loa (eye worm) leukotriene A4 hydrolase 0.0024 0.0035 0.0031
Loa Loa (eye worm) hypothetical protein 0.0045 0.0174 0.0169
Loa Loa (eye worm) hypothetical protein 0.0025 0.0038 0.0034
Mycobacterium tuberculosis Probable oxidoreductase 0.0185 0.1076 0.2912
Brugia malayi Animal haem peroxidase family protein 0.0027 0.0055 0.0055
Treponema pallidum NADH oxidase 0.0025 0.0043 0.0017
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Onchocerca volvulus 0.0036 0.0111 0.0097
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0474 0.141
Loa Loa (eye worm) serotonin transporter b 0.1565 1 1
Brugia malayi Serotonin receptor 0.0036 0.0111 0.0111
Onchocerca volvulus 0.0457 0.2835 0.2824
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0036 0.0111 0.0101
Loa Loa (eye worm) hypothetical protein 0.007 0.0332 0.0327
Loa Loa (eye worm) animal heme peroxidase 0.0027 0.0055 0.005
Echinococcus multilocularis somatostatin receptor 0.0036 0.0111 0.0101
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0291 0.0263
Echinococcus multilocularis peroxidasin 0.0027 0.0055 0.0046
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0147 0.0833 0.2123
Onchocerca volvulus Bile acid receptor homolog 0.0096 0.0503 0.049
Trypanosoma cruzi trypanothione reductase, putative 0.0025 0.0043 0.0037
Onchocerca volvulus 0.0027 0.0055 0.0041
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0034 0.01 0.01
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0141 0.0587
Echinococcus granulosus tachykinin peptides receptor 99D 0.0036 0.0111 0.0101
Brugia malayi hypothetical protein 0.0036 0.0111 0.0111
Echinococcus multilocularis fmrfamide receptor 0.0036 0.0111 0.0101
Echinococcus multilocularis tar DNA binding protein 0.0073 0.0355 0.0345
Brugia malayi Histone deacetylase family protein 0.0092 0.0474 0.0474
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0038 0.0126 0.0261
Loa Loa (eye worm) hypothetical protein 0.0079 0.0391 0.0387
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0262 0.0678
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0025 0.0043 0.0014
Brugia malayi hypothetical protein 0.0027 0.0055 0.0055
Brugia malayi hypothetical protein 0.0036 0.0111 0.0111
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0154 0.0875 0.0866
Loa Loa (eye worm) neuropeptide F receptor 0.0036 0.0111 0.0106
Echinococcus multilocularis tyrosine kinase 0.0025 0.0038 0.0029
Echinococcus multilocularis phosphatidylinositol 5 phosphate 4 kinase type 2 0.0158 0.0902 0.0893
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0133 0.0742 0.0733
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0283 0.0675
Mycobacterium ulcerans hypothetical protein 0.0107 0.0573 0.1532
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0099 0.0519 0.0509
Mycobacterium ulcerans hypothetical protein 0.0138 0.077 0.2073
Brugia malayi Inositol-1 0.0043 0.0157 0.0157
Echinococcus multilocularis g protein coupled receptor 0.0036 0.0111 0.0101
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0112 0.0605 0.058
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0141 0.0506
Brugia malayi nuclear receptor RXR 0.0051 0.0209 0.0209
Schistosoma mansoni opsin-like receptor 0.0036 0.0111 0.0082
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0036 0.0111 0.0082
Trypanosoma cruzi histone deacetylase, putative 0.0092 0.0474 0.1174
Schistosoma mansoni DNA polymerase eta 0.0061 0.0275 0.0247
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.005
Echinococcus granulosus geminin 0.0261 0.157 0.1562
Loa Loa (eye worm) glutamate receptor 2 0.0122 0.0667 0.0663
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0111 0.0082
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0166 0.0956 0.2583
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0036 0.011 0.0429
Brugia malayi tailless protein 0.0045 0.0174 0.0174
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0111 0.0082
Brugia malayi Animal haem peroxidase family protein 0.0027 0.0055 0.0055
Loa Loa (eye worm) animal heme peroxidase 0.0027 0.0055 0.005
Loa Loa (eye worm) RecQ helicase 0.0053 0.0225 0.022
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0036 0.011 0.024
Echinococcus multilocularis nmda type glutamate receptor 0.0023 0.0029 0.002
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0025 0.0043 0.0085
Brugia malayi nuclear receptor NHR-88 0.0045 0.0174 0.0174
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0025 0.0043 0.0079
Loa Loa (eye worm) hypothetical protein 0.0051 0.0209 0.0205
Echinococcus granulosus histone acetyltransferase KAT2B 0.0048 0.0192 0.0183
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.005
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0036 0.0111 0.0106
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0065 0.0303 0.0293
Schistosoma mansoni nuclear receptor 0.0045 0.0174 0.0145
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0474 0.141
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0096 0.0503 0.0475
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0266 0.1598 0.1598
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0048 0.0192 0.0853
Trypanosoma brucei DNA polymerase IV, putative 0.0055 0.0239 0.0559
Trypanosoma brucei polo-like protein kinase 0.0092 0.0474 0.1179
Brugia malayi hypothetical protein 0.0024 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.007 0.0331 0.0327
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0024 0.0035 0.0043
Loa Loa (eye worm) G-protein coupled receptor 0.0036 0.0111 0.0106
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0038 0.0126 0.0255
Loa Loa (eye worm) nuclear hormone receptor 0.0045 0.0174 0.0169
Loa Loa (eye worm) histone deacetylase 3 0.0322 0.1963 0.1959
Echinococcus multilocularis neuropeptides capa receptor 0.0036 0.0111 0.0101
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0034 0.01 0.0377
Echinococcus granulosus histone deacetylase 6 0.0092 0.0474 0.0465
Schistosoma mansoni sodium/chloride dependent transporter 0.0266 0.1598 0.1573
Loa Loa (eye worm) hypothetical protein 0.0457 0.2835 0.2831
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.0111 0.0101
Schistosoma mansoni hypothetical protein 0.0028 0.006 0.0031
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0149 0.0323
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0051 0.0209 0.02
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.005
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0262 0.1212
Plasmodium vivax amine transporter, putative 0.0266 0.1598 0.8114
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Echinococcus granulosus alpha 1A adrenergic receptor 0.0036 0.0111 0.0101
Echinococcus multilocularis Protein lozenge 0.0057 0.0251 0.0241
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0166 0.0956 0.2583
Plasmodium falciparum SUMO-activating enzyme subunit 2 0.0033 0.0092 0.0334
Schistosoma mansoni histamine h1 receptor 0.0036 0.0111 0.0082
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0036 0.0111 0.0101
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0233 0.1387 0.1379
Plasmodium vivax histone deacetylase 2, putative 0.0092 0.0474 0.231
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0068 0.0322 0.0312
Loa Loa (eye worm) hypothetical protein 0.0089 0.0453 0.0449
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0111 0.0101
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0312 0.1895 0.4925
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0045 0.0174 0.016
Loa Loa (eye worm) aminopeptidase N 0.0068 0.0322 0.0317
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0063 0.0287 0.0258
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0096 0.0503 0.0494
Brugia malayi mbt repeat family protein 0.0087 0.0441 0.0441
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0474 0.141
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0283 0.0675
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0183 0.0183
Echinococcus granulosus glutamate receptor 2 0.0153 0.0872 0.0863
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0118 0.0641 0.0637
Echinococcus granulosus phosphatidylinositol 5 phosphate 4 kinase type 2 0.0158 0.0902 0.0893
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0023 0.0029 0.002
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0048 0.0192 0.0853
Leishmania major eukaryotic translation initiation factor-like protein 0.0036 0.011 0.0219
Echinococcus granulosus zinc finger protein 0.0039 0.0134 0.0124
Echinococcus granulosus Nuclear hormone receptor HR96 0.0045 0.0174 0.0164
Echinococcus granulosus dro:myosuppressin receptor 0.0036 0.0111 0.0101
Schistosoma mansoni retinoic acid receptor RXR 0.0249 0.1487 0.1462
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0063 0.0287 0.0686
Plasmodium falciparum histone deacetylase 2 0.0092 0.0474 0.231
Schistosoma mansoni opsin-like receptor 0.0036 0.0111 0.0082
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0096 0.0503 0.0494
Onchocerca volvulus 0.0266 0.1598 0.1586
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0076 0.013
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0111 0.0082
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0076 0.013
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.005
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0166 0.0956 0.2583
Treponema pallidum sodium- and chloride- dependent transporter 0.1565 1 1
Mycobacterium ulcerans endonuclease IV 0.0079 0.0391 0.1034
Brugia malayi nuclear receptor NHR-67 0.0045 0.0174 0.0174
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Echinococcus multilocularis serotonin receptor 0.0091 0.0469 0.046
Brugia malayi TATA binding protein associated factor 0.0024 0.0035 0.0035
Plasmodium falciparum SUMO-activating enzyme subunit 1 0.005 0.0202 0.0902
Loa Loa (eye worm) carboxylesterase 0.007 0.0332 0.0327
Brugia malayi hypothetical protein 0.0036 0.0111 0.0111
Onchocerca volvulus Dual oxidase homolog 0.0027 0.0055 0.0041
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0605 0.1833
Onchocerca volvulus 0.0024 0.0035 0.0021
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0262 0.0252
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0034 0.01 0.0377
Brugia malayi acetyltransferase, GNAT family protein 0.0154 0.0875 0.0875
Trichomonas vaginalis histone deacetylase, putative 0.0322 0.1963 0.6201
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0076 0.0169
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.0111 0.0101
Onchocerca volvulus 0.0027 0.0055 0.0041
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0064 0.0291 0.1365
Echinococcus granulosus histone acetyltransferase MYST2 0.0099 0.0519 0.0509
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0031 0.0081 0.0071
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0025 0.0043 0.0034
Echinococcus granulosus histone deacetylase 1 0.0322 0.1963 0.1955
Loa Loa (eye worm) hypothetical protein 0.0096 0.0503 0.0499
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0147 0.0833 0.2128
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0266 0.1598 0.1573
Loa Loa (eye worm) hypothetical protein 0.0045 0.0174 0.0169
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0025 0.0043 0.0043
Toxoplasma gondii aminopeptidase N, putative 0.0024 0.0035 0.0043
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0233 0.1387 0.1379
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0609 0.3817 0.3817
Trypanosoma cruzi ubiquitin-activating enzyme, putative 0.0028 0.0062 0.0086
Schistosoma mansoni hypothetical protein 0.0045 0.0171 0.0142
Echinococcus granulosus g protein coupled receptor 0.0036 0.0111 0.0101
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0036 0.0111 0.0101
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0045 0.0174 0.0164
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0024
Trichomonas vaginalis histone deacetylase, putative 0.0322 0.1963 0.6201
Brugia malayi Nuclear hormone receptor E75 0.0045 0.0174 0.0174
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0166 0.0956 0.2583
Brugia malayi Peroxidasin 0.0027 0.0055 0.0055
Trypanosoma cruzi Aminopeptidase M1, putative 0.0068 0.0322 0.0772
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0095 0.0492 0.0483
Plasmodium vivax thioredoxin reductase, putative 0.0073 0.0352 0.1677
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0076 0.0253
Onchocerca volvulus 0.0158 0.0902 0.0888
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.0111 0.0101
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0076 0.0253
Loa Loa (eye worm) hypothetical protein 0.0035 0.0105 0.01
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0266 0.1598 0.8114
Echinococcus granulosus SUMO activating enzyme subunit 1 0.005 0.0202 0.0192
Schistosoma mansoni hypothetical protein 0.0035 0.0105 0.0076
Brugia malayi Carboxylesterase family protein 0.007 0.0332 0.0332
Schistosoma mansoni hypothetical protein 0.0261 0.157 0.1545
Echinococcus granulosus histone deacetylase 7 0.0092 0.0474 0.0465
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0163 0.0354
Leishmania major histone deacetylase, putative 0.0322 0.1963 0.5108
Loa Loa (eye worm) glutamate receptor 1 0.0175 0.1014 0.101
Entamoeba histolytica hypothetical protein 0.0039 0.013 0.0534
Trypanosoma cruzi ISWI complex protein 0.0028 0.006 0.0081
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Brugia malayi Histone deacetylase family protein 0.0092 0.0474 0.0474
Brugia malayi ThiF family protein 0.0033 0.0092 0.0092
Onchocerca volvulus Chorion peroxidase homolog 0.0027 0.0055 0.0041
Plasmodium vivax SET domain protein, putative 0.0064 0.0291 0.1365
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0041 0.0145 0.0116
Echinococcus granulosus histone deacetylase 6 0.0092 0.0474 0.0465
Mycobacterium tuberculosis Probable reductase 0.0166 0.0956 0.2583
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0034 0.01 0.009
Onchocerca volvulus 0.0036 0.0111 0.0097
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0076 0.0253
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0024 0.0035 0.0022
Schistosoma mansoni histone deacetylase 0.0322 0.1963 0.1939
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0096 0.0503 0.0503
Loa Loa (eye worm) translation initiation factor 4E 0.0036 0.011 0.0105
Brugia malayi G-protein coupled receptor 0.0036 0.0111 0.0111
Echinococcus granulosus atrial natriuretic peptide receptor 0.0023 0.0029 0.002
Giardia lamblia Kinase, PLK 0.0092 0.0474 0.2242
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0045 0.0174 0.0169
Echinococcus granulosus fetal alzheimer antigen falz 0.0041 0.0145 0.0135
Mycobacterium ulcerans aminopeptidase N PepN 0.0068 0.0322 0.0844
Brugia malayi Guanylyl cyclase protein 23 0.0025 0.0038 0.0038
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0111 0.0101
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.0111 0.0101
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0036 0.011 0.024
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0283 0.0669
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0073 0.0352 0.0925
Loa Loa (eye worm) G-protein coupled receptor 0.0036 0.0111 0.0106
Loa Loa (eye worm) hypothetical protein 0.0042 0.0149 0.0144
Echinococcus granulosus neuropeptides capa receptor 0.0036 0.0111 0.0101
Loa Loa (eye worm) RGC/RGC protein kinase 0.0025 0.0038 0.0034
Schistosoma mansoni tyrosine kinase 0.0025 0.0038 0.0009
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0112 0.0606 0.0597
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0079 0.0391 0.1882
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Echinococcus granulosus neuropeptide s receptor 0.0271 0.1631 0.1623
Echinococcus multilocularis histone deacetylase 6 0.0092 0.0474 0.0465
Onchocerca volvulus 0.0042 0.0149 0.0135
Echinococcus granulosus histone deacetylase 8 0.0092 0.0474 0.0465
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0068 0.0322 0.0312
Brugia malayi Nuclear hormone receptor E75 0.0045 0.0174 0.0174
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0355 0.0326
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0036 0.011 0.0213
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0025 0.0043 0.0079
Echinococcus granulosus methyl CpG binding domain protein 2 0.0031 0.0081 0.0071
Brugia malayi neuropeptide F receptor 0.0036 0.0111 0.0111
Echinococcus multilocularis dna polymerase kappa 0.0062 0.0283 0.0273
Onchocerca volvulus 0.0036 0.0111 0.0097
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0157 0.0342
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0024 0.0035 0.0026
Schistosoma mansoni nuclear receptor nhr-48 0.0045 0.0174 0.0145
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0111 0.0082
Schistosoma mansoni glutamate receptor kainate 0.021 0.1238 0.1212
Echinococcus multilocularis inositol monophosphatase 1 0.0043 0.0157 0.0147
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0023 0.0029 0.002
Echinococcus granulosus histone deacetylase 3 0.0322 0.1963 0.1955
Brugia malayi follicle stimulating hormone receptor 0.0036 0.0111 0.0111
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0262 0.0678
Brugia malayi Bromodomain containing protein 0.014 0.0786 0.0786
Echinococcus granulosus ecdysone induced protein 78C 0.0096 0.0503 0.0494
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0076 0.0253
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0025 0.0043 0.0037
Brugia malayi larval opioid receptor 0.0036 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0008
Toxoplasma gondii exonuclease III APE 0.0029 0.0068 0.021
Loa Loa (eye worm) hypothetical protein 0.0266 0.1598 0.1594
Plasmodium vivax glutathione reductase, putative 0.0073 0.0352 0.1677
Loa Loa (eye worm) hypothetical protein 0.0164 0.0939 0.0935
Trypanosoma brucei Aph-1 protein, putative 0.0046 0.0177 0.0395
Loa Loa (eye worm) hypothetical protein 0.0266 0.1598 0.1594
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0025 0.0043 0.0037
Echinococcus multilocularis musashi 0.0042 0.0149 0.0139
Plasmodium falciparum histone deacetylase, putative 0.0092 0.0474 0.231
Schistosoma mansoni biogenic amine (5HT) receptor 0.0091 0.0469 0.0441
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0036 0.0111 0.0101
Echinococcus granulosus fmrfamide receptor 0.0036 0.0111 0.0101
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0076 0.0311
Trypanosoma brucei Aminopeptidase M1, putative 0.0068 0.0322 0.0778
Trypanosoma brucei ubiquitin-activating enzyme E1, putative 0.0033 0.0092 0.017
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0036 0.0111 0.0082
Echinococcus granulosus 6 phosphofructokinase 0.0112 0.0605 0.0596
Toxoplasma gondii hypothetical protein 0.005 0.0205 0.0919
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0024 0.0035 0.0026
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0025 0.0043 0.0079
Toxoplasma gondii histone deacetylase HDAC3 0.0322 0.1963 1
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0112 0.0605 0.1525
Brugia malayi PHD-finger family protein 0.0049 0.0197 0.0197
Brugia malayi Histone deacetylase 1 0.0322 0.1963 0.1963
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0068 0.0322 0.0293
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0079 0.0391 0.1034
Mycobacterium ulcerans DNA polymerase IV 0.0062 0.0283 0.0736
Loa Loa (eye worm) DR-78 0.0045 0.0174 0.0169
Loa Loa (eye worm) hypothetical protein 0.0045 0.0174 0.0169
Onchocerca volvulus 0.0266 0.1598 0.1586
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0068 0.0322 0.0922
Schistosoma mansoni glutamate receptor kainate 0.0122 0.0667 0.064
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0111 0.0082
Entamoeba histolytica hypothetical protein 0.0023 0.0029 0.0012
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.005
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.1565 1 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.0096 0.0503 0.0475
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0029 0.0068 0.021
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0037 0.012 0.048
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.005
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0029 0.0068 0.0063
Onchocerca volvulus 0.0045 0.0174 0.016
Loa Loa (eye worm) hypothetical protein 0.0021 0.0014 0.001
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0025 0.0043 0.0043
Trypanosoma brucei C-8 sterol isomerase, putative 0.0609 0.3817 1
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0154 0.0875 0.0848
Brugia malayi ORL1-like opioid receptor 0.0036 0.0111 0.0111
Echinococcus granulosus acetylcholinesterase 0.007 0.0332 0.0323
Schistosoma mansoni thyroid hormone receptor 0.0226 0.1343 0.1318
Echinococcus multilocularis neuropeptide Y receptor 0.0036 0.0111 0.0101
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0283 0.0675
Trypanosoma cruzi trypanothione reductase, putative 0.0073 0.0352 0.0851
Loa Loa (eye worm) TAR-binding protein 0.0073 0.0355 0.035
Trypanosoma brucei PAB1-binding protein , putative 0.0033 0.0092 0.0171
Echinococcus multilocularis neuropeptide FF receptor 2 0.0036 0.0111 0.0101
Trichomonas vaginalis DNA helicase recq, putative 0.0038 0.0126 0.0291
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0266 0.1598 0.1573
Loa Loa (eye worm) melatonin receptor type 1A 0.0036 0.0111 0.0106
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0068 0.0322 0.0312
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0096 0.0503 0.0499
Trypanosoma cruzi polo-like protein kinase, putative 0.0092 0.0474 0.1173
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0036 0.0111 0.0097
Brugia malayi nuclear hormone receptor family member nhr-6 0.0045 0.0174 0.0174
Trichomonas vaginalis histone deacetylase, putative 0.0322 0.1963 0.6201
Brugia malayi ecdysone receptor 0.0045 0.0174 0.0174
Echinococcus multilocularis histone acetyltransferase MYST2 0.0099 0.0519 0.0509
Echinococcus granulosus g-protein coupled receptor 0.0036 0.0111 0.0101
Schistosoma mansoni hypothetical protein 0.0036 0.0111 0.0082
Trichomonas vaginalis histone deacetylase, putative 0.0322 0.1963 0.6201
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0023 0.0029 0.0024
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0096 0.0503 0.0503
Onchocerca volvulus 0.0036 0.0111 0.0097
Onchocerca volvulus 0.0036 0.0111 0.0097
Brugia malayi Steroid receptor seven-up type 2 0.0096 0.0503 0.0503
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0045 0.0171 0.0162
Brugia malayi nuclear receptor RXR 0.0045 0.0174 0.0174
Brugia malayi Peptidase family M1 containing protein 0.0024 0.0035 0.0035
Schistosoma mansoni glutamate receptor AMPA 0.0122 0.0667 0.064
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Schistosoma mansoni biogenic amine receptor 0.0036 0.0111 0.0082
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.0024 0.0035 0.0006
Onchocerca volvulus 0.0505 0.3144 0.3134
Trypanosoma brucei DNA polymerase IV, putative 0.0062 0.0283 0.0675
Brugia malayi G protein-coupled receptor F59B2.13 0.0036 0.0111 0.0111
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0283 0.0669
Leishmania major histone deacetylase, putative 0.0322 0.1963 0.5108
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0035 0.0105 0.0096
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0102 0.0538 0.135
Brugia malayi glutathione reductase 0.0073 0.0352 0.0352
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0096 0.0503 0.0494
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0036 0.0111 0.0111
Echinococcus multilocularis nmda type glutamate receptor 0.0062 0.0284 0.0274
Echinococcus multilocularis ecdysone induced protein 78C 0.0096 0.0503 0.0494
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0036 0.0111 0.0101
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0096 0.0503 0.0503
Loa Loa (eye worm) runx1 0.0057 0.0251 0.0246
Loa Loa (eye worm) hypothetical protein 0.0045 0.0174 0.0169
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0051 0.0209 0.0205
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0036 0.0111 0.0111
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0266 0.1598 0.159
Loa Loa (eye worm) hypothetical protein 0.0095 0.0492 0.0487
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0096 0.0503 0.0494
Brugia malayi Dopamine receptor protein 1 0.0036 0.0111 0.0111
Leishmania major DNA polymerase eta, putative 0.0037 0.012 0.0245
Trypanosoma brucei trypanothione reductase 0.0073 0.0352 0.0857
Echinococcus multilocularis receptor type guanylyl cyclase 0.0025 0.0038 0.0029
Schistosoma mansoni ATP-binding cassette transporter 0.0122 0.0667 0.064
Schistosoma mansoni DNA helicase recq5 0.0034 0.01 0.0071
Schistosoma mansoni growth hormone secretagogue receptor 0.0036 0.0111 0.0082
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0064 0.0291 0.0282
Trichomonas vaginalis bromodomain-containing protein, putative 0.0048 0.0192 0.0504
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0096 0.0503 0.0494
Loa Loa (eye worm) hypothetical protein 0.0054 0.0227 0.0222
Schistosoma mansoni gamma-secretase subunit aph-1 0.0118 0.0641 0.0614
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0068 0.0322 0.0312
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0127 0.0265
Brugia malayi Intermediate filament tail domain containing protein 0.0042 0.0149 0.0149
Onchocerca volvulus 0.0036 0.0111 0.0097
Loa Loa (eye worm) hypothetical protein 0.0051 0.0209 0.0205
Brugia malayi Blistered cuticle protein 3 0.0027 0.0055 0.0055
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0605 0.1833
Trypanosoma cruzi histone deacetylase, putative 0.0092 0.0474 0.1174
Onchocerca volvulus 0.0047 0.0183 0.0169
Loa Loa (eye worm) inositol-1 0.0043 0.0157 0.0152
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0025 0.0043 0.0085
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0048 0.0192 0.0504
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0042 0.0149 0.0144
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0051 0.0209 0.02
Echinococcus granulosus nuclear factor of activated T cells 5 0.0038 0.0123 0.0114
Schistosoma mansoni zinc finger protein 0.0028 0.006 0.0031
Schistosoma mansoni hypothetical protein 0.013 0.072 0.0692
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0029 0.0068 0.0058
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0063 0.0287 0.0287
Toxoplasma gondii hypothetical protein 0.0266 0.1598 0.8114
Toxoplasma gondii eukaryotic initiation factor-2B, gamma subunit, putative 0.0107 0.0573 0.2821
Mycobacterium tuberculosis Probable dehydrogenase 0.0166 0.0956 0.2583
Schistosoma mansoni sumo-1-activating enzyme E1a 0.0045 0.0172 0.0143
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0025 0.0043 0.0043
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0262 0.0678
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0024 0.0035 0.0043
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0055 0.0237 0.0232
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0262 0.0619
Onchocerca volvulus Peroxidase homolog 0.0027 0.0055 0.0041
Schistosoma mansoni Tata binding protein associated factor (M01 family) 0.0024 0.0035 0.0006
Loa Loa (eye worm) hypothetical protein 0.023 0.1366 0.1362
Onchocerca volvulus Peroxidase homolog 0.0027 0.0055 0.0041
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Schistosoma mansoni NAALADASE L peptidase (M28 family) 0.0085 0.0433 0.0404
Schistosoma mansoni neuropeptide receptor 0.0036 0.0111 0.0082
Trypanosoma brucei Eukaryotic translation initiation factor 4E-1 0.0036 0.011 0.0219
Entamoeba histolytica hypothetical protein 0.0039 0.013 0.0534
Echinococcus multilocularis G protein coupled receptor 139 0.0036 0.0111 0.0101
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0036 0.011 0.0213
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0105 0.0105
Echinococcus granulosus dna polymerase eta 0.0061 0.0275 0.0266
Echinococcus multilocularis dna polymerase eta 0.0061 0.0275 0.0266
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0036 0.0111 0.0101
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0025 0.0043 0.0034
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0025 0.0043 0.0085
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0065 0.0303 0.0293
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0029 0.0068 0.0058
Schistosoma mansoni myosin xvIII 0.0036 0.0111 0.0082
Plasmodium vivax ubiquitin activating enzyme, putative 0.005 0.0202 0.0902
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0111 0.0082
Schistosoma mansoni methyl-cpg binding protein mbd 0.0031 0.0081 0.0051
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.0585 0.366 1
Schistosoma mansoni inositol monophosphatase 0.0043 0.0157 0.0128
Plasmodium falciparum ataxin-2 like protein, putative 0.0033 0.0092 0.0334
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0038 0.0126 0.0261
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Onchocerca volvulus 0.0036 0.0111 0.0097
Brugia malayi putative neuropeptide receptor NPR1 0.0036 0.0111 0.0111
Brugia malayi ImpB/MucB/SamB family protein 0.0035 0.0105 0.0105
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0096 0.0503 0.0475
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0111 0.0101
Brugia malayi Glutamate receptor 2 precursor 0.0175 0.1014 0.1014
Echinococcus multilocularis thioredoxin glutathione reductase 0.0073 0.0352 0.0342
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0036 0.0111 0.0101
Schistosoma mansoni peroxidasin 0.0027 0.0055 0.0026
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0262 0.0252
Loa Loa (eye worm) pip kinase 2 0.0158 0.0902 0.0897
Brugia malayi ThiF family protein 0.005 0.0202 0.0202
Onchocerca volvulus 0.0036 0.0111 0.0097
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.0111 0.0101
Schistosoma mansoni hypothetical protein 0.0533 0.3328 0.3309
Brugia malayi histone deacetylase 3 (HD3) 0.0322 0.1963 0.1963
Loa Loa (eye worm) hypothetical protein 0.0096 0.0503 0.0499
Schistosoma mansoni neuropeptide F-like receptor 0.0036 0.0111 0.0082
Schistosoma mansoni hypothetical protein 0.0039 0.013 0.0101
Brugia malayi gamma-secretase subunit aph-1 0.0118 0.0641 0.0641
Brugia malayi Metabotropic glutamate receptor precursor. 0.0023 0.0029 0.0029
Schistosoma mansoni adenoreceptor 0.0036 0.0111 0.0082
Brugia malayi conserved hypotetical protein 0.0045 0.0174 0.0174
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0102 0.0538 0.0511
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0023 0.0029 0.0029
Treponema pallidum exodeoxyribonuclease (exoA) 0.0029 0.0068 0.0041
Schistosoma mansoni nuclear hormone receptor 0.0096 0.0503 0.0475
Brugia malayi 6-phosphofructokinase 0.0112 0.0605 0.0605
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0096 0.0503 0.0503
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0029 0.0068 0.0101
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0076 0.0049
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0112 0.0605 0.162
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0355 0.0326
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0031
Loa Loa (eye worm) hypothetical protein 0.0096 0.0503 0.0499
Brugia malayi hypothetical protein 0.0266 0.1598 0.1598
Trypanosoma cruzi Aph-1 protein, putative 0.0046 0.0177 0.0389
Schistosoma mansoni glutamate receptor kainate 0.021 0.1238 0.1212
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0025 0.0043 0.0085
Schistosoma mansoni neuropeptide receptor 0.0036 0.0111 0.0082
Brugia malayi Nuclear hormone receptor-like 1 0.0096 0.0503 0.0503
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0024
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0034 0.01 0.009
Onchocerca volvulus 0.0266 0.1598 0.1586
Loa Loa (eye worm) hypothetical protein 0.0134 0.0744 0.0739
Echinococcus granulosus orexin receptor type 2 0.0036 0.0111 0.0101
Loa Loa (eye worm) hypothetical protein 0.0051 0.0209 0.0205
Schistosoma mansoni amine GPCR 0.0036 0.0111 0.0082
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0036 0.0111 0.0082
Onchocerca volvulus Histone deacetylase 10 homolog 0.0092 0.0474 0.046
Trypanosoma brucei histone deacetylase, putative 0.0092 0.0474 0.118
Schistosoma mansoni ap endonuclease 0.0029 0.0068 0.0038
Brugia malayi TAR-binding protein 0.0073 0.0355 0.0355
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0249 0.1487 0.1478
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0147 0.0833 0.2128
Loa Loa (eye worm) intermediate filament protein 0.0042 0.0149 0.0144
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0076 0.0253
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0096 0.0503 0.0499
Plasmodium falciparum glutathione reductase 0.0025 0.0043 0.0085
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0079 0.0391 0.1882
Echinococcus multilocularis allatostatin A receptor 0.0036 0.0111 0.0101
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0283 0.0675
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0099 0.0518 0.0509
Loa Loa (eye worm) steroid hormone receptor 0.0096 0.0503 0.0499
Loa Loa (eye worm) hypothetical protein 0.0081 0.0403 0.0398
Loa Loa (eye worm) glutathione reductase 0.0073 0.0352 0.0347
Brugia malayi Pip kinase protein 2 0.0158 0.0902 0.0902
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0096 0.0503 0.0503
Loa Loa (eye worm) hypothetical protein 0.0122 0.0667 0.0663
Echinococcus granulosus neuropeptide Y receptor 0.0036 0.0111 0.0101
Schistosoma mansoni amine GPCR 0.0036 0.0111 0.0082
Loa Loa (eye worm) DEAH box polypeptide 35 0.0021 0.0013 0.0008
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0092 0.0474 0.0464
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Trypanosoma cruzi histone deacetylase 1, putative 0.0322 0.1963 0.5105
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0044 0.0163 0.0354
Schistosoma mansoni histone deacetylase hda2 0.0092 0.0474 0.0446
Onchocerca volvulus 0.0064 0.0291 0.0277
Brugia malayi hypothetical protein 0.0036 0.0111 0.0111
Onchocerca volvulus 0.0036 0.0111 0.0097
Trypanosoma cruzi histone deacetylase 1, putative 0.0322 0.1963 0.5105
Leishmania major hypothetical protein, conserved 0.0028 0.006 0.0087
Entamoeba histolytica hypothetical protein, conserved 0.0138 0.077 0.3839
Schistosoma mansoni amine GPCR 0.0528 0.3295 0.3275
Echinococcus multilocularis NMDA receptor 0.0133 0.0742 0.0733
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0609 0.3817 1
Loa Loa (eye worm) acetyltransferase 0.0154 0.0875 0.087
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0045 0.0174 0.0174
Echinococcus multilocularis neuropeptide receptor 0.0036 0.0111 0.0101
Entamoeba histolytica recQ family helicase, putative 0.0038 0.0126 0.0511
Schistosoma mansoni amine GPCR 0.0036 0.0111 0.0082
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0024 0.0035 0.0016
Toxoplasma gondii hypothetical protein 0.005 0.0202 0.0902
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0036 0.0111 0.0082
Brugia malayi hypothetical protein 0.0045 0.0174 0.0174
Echinococcus multilocularis histone deacetylase 6 0.0092 0.0474 0.0465
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0096 0.0503 0.0499
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0474 0.141
Plasmodium vivax hypothetical protein, conserved 0.0266 0.1598 0.8114
Schistosoma mansoni kinase 0.0047 0.0182 0.0153
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0044 0.0163 0.036
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0283 0.0675
Loa Loa (eye worm) TYRA-2 protein 0.0036 0.0111 0.0106
Echinococcus granulosus carboxylesterase 5A 0.007 0.0332 0.0323
Echinococcus multilocularis histone deacetylase 3 0.0322 0.1963 0.1955
Trypanosoma brucei histone deacetylase 1 0.0322 0.1963 0.5108
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0266 0.1598 0.1594
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0025 0.0043 0.0105
Brugia malayi Glutamate receptor 1 precursor 0.0175 0.1014 0.1014
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0096 0.0503 0.0494
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0035 0.0105 0.0096
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0024
Leishmania major histone deacetylase, putative 0.0092 0.0474 0.118
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0034 0.01 0.01
Brugia malayi Receptor family ligand binding region containing protein 0.0025 0.0038 0.0038
Echinococcus multilocularis L aminoadipate semialdehyde 0.0081 0.0403 0.0393
Loa Loa (eye worm) acetylcholinesterase 1 0.007 0.0332 0.0327
Trichomonas vaginalis ap endonuclease, putative 0.0029 0.0068 0.0104
Brugia malayi neuropeptide F receptor 0.0036 0.0111 0.0111
Entamoeba histolytica hypothetical protein 0.0039 0.013 0.0534
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0024 0.0035 0.0016
Loa Loa (eye worm) thioredoxin reductase 0.0073 0.0352 0.0347
Onchocerca volvulus 0.0081 0.0403 0.0389
Echinococcus multilocularis sex peptide receptor 0.0036 0.0111 0.0101
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0043 0.0157 0.039
Toxoplasma gondii aminopeptidase n, putative 0.0024 0.0035 0.0043
Echinococcus granulosus hypothetical protein 0.0036 0.0111 0.0101
Brugia malayi serine/threonine-protein kinase plk-2 0.0092 0.0474 0.0474
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0283 0.0675
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.013 0.072 0.0711
Toxoplasma gondii NADPH-glutathione reductase 0.0025 0.0043 0.0085
Brugia malayi RNA binding protein 0.0073 0.0355 0.0355
Echinococcus multilocularis acetylcholinesterase 0.007 0.0332 0.0323
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0024 0.0035 0.0016
Trypanosoma brucei DNA polymerase eta, putative 0.0061 0.0275 0.0655
Toxoplasma gondii histone deacetylase HDAC4 0.0092 0.0474 0.231
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0266 0.1598 0.1573
Echinococcus multilocularis SAM and MBT domain containing protein 0.0087 0.0441 0.0432
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Onchocerca volvulus 0.0027 0.0055 0.0041
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0092 0.0474 0.0469
Schistosoma mansoni hypothetical protein 0.0036 0.0111 0.0082
Echinococcus granulosus neuropeptides capa receptor 0.0036 0.0111 0.0101
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0036 0.0111 0.0082
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Brugia malayi mbt repeat family protein 0.0087 0.0441 0.0441
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0042 0.0149 0.037
Schistosoma mansoni hypothetical protein 0.0261 0.157 0.1545
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0096 0.0503 0.0503
Echinococcus granulosus Nuclear hormone receptor HR96 0.0045 0.0174 0.0164
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0102 0.0538 0.0538
Echinococcus multilocularis SUMO activating enzyme subunit 2 0.0033 0.0092 0.0082
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0029 0.0068 0.0146
Echinococcus granulosus histone deacetylase 0.0092 0.0474 0.0465
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0045 0.0174 0.0164
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0266 0.1598 1
Loa Loa (eye worm) hypothetical protein 0.0099 0.0519 0.0514
Loa Loa (eye worm) hypothetical protein 0.0092 0.0474 0.047
Loa Loa (eye worm) hypothetical protein 0.0322 0.1963 0.1959
Echinococcus multilocularis g-protein coupled receptor 0.0036 0.0111 0.0101
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Schistosoma mansoni histone deacetylase hda2 0.0092 0.0474 0.0446
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0185 0.1076 0.2912
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0036 0.0111 0.0101
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0025 0.0043 0.0037
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0024
Loa Loa (eye worm) hypothetical protein 0.0051 0.0209 0.0205
Echinococcus granulosus eukaryotic translation initiation factor 4E 0.0036 0.011 0.01
Schistosoma mansoni hypothetical protein 0.0047 0.0183 0.0154
Plasmodium falciparum thioredoxin reductase 0.0073 0.0352 0.1677
Brugia malayi Melatonin receptor type 1A 0.0036 0.0111 0.0111
Echinococcus granulosus peptide allatostatin:somatostatin 0.0036 0.0111 0.0101
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0068 0.0322 0.0312
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0029 0.0068 0.0107
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0023 0.0029 0.002
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0174 0.0446
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0076 0.013
Loa Loa (eye worm) hypothetical protein 0.1565 1 1
Leishmania major eukaryotic translation initiation factor eIF-4E, putative 0.0036 0.011 0.0219
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.005
Plasmodium vivax ataxin-2 like protein, putative 0.0033 0.0092 0.0334
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0025 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Echinococcus granulosus histone acetyltransferase KAT2B 0.0145 0.082 0.0811
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0076 0.013
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0119 0.0647 0.062
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0312 0.1895 0.4925
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0102 0.0538 0.135
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0036 0.0111 0.0101
Onchocerca volvulus 0.0036 0.0111 0.0097
Brugia malayi cytoplasmic intermediate filament protein 0.0022 0.0024 0.0024
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0068 0.0322 0.0778
Echinococcus granulosus sex peptide receptor 0.0036 0.0111 0.0101
Schistosoma mansoni neuropeptide receptor 0.0036 0.0111 0.0082
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0122 0.0667 0.0658
Schistosoma mansoni ubiquitin-activating enzyme E1b 0.0033 0.0092 0.0062
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0414 0.2559 0.2552
Echinococcus multilocularis SUMO activating enzyme subunit 1 0.005 0.0202 0.0192
Loa Loa (eye worm) animal heme peroxidase 0.0027 0.0055 0.005
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0036 0.0111 0.0101
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.0605 0.2986
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0112 0.0606 0.0597
Trichomonas vaginalis glutathione reductase, putative 0.0025 0.0043 0.0026
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0283 0.0675
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0474 0.141
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0474 0.141
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0102 0.0538 0.0534
Brugia malayi Peptidase family M1 containing protein 0.0068 0.0322 0.0322
Mycobacterium ulcerans hypothetical protein 0.0138 0.077 0.2073
Leishmania major trypanothione reductase 0.0073 0.0352 0.0857
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0492 0.0464
Treponema pallidum licC protein (licC) 0.0107 0.0573 0.0548
Loa Loa (eye worm) hypothetical protein 0.0096 0.0503 0.0499
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0029 0.0068 0.0112
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0102 0.0538 0.2642
Giardia lamblia Sgs1 DNA helicase, putative 0.0034 0.01 0.0295
Echinococcus granulosus g protein coupled receptor 0.0036 0.0111 0.0101
Loa Loa (eye worm) norepinephrine transporter 0.1565 1 1
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0068 0.0322 0.0312
Plasmodium falciparum thioredoxin reductase 0.0025 0.0043 0.0085
Loa Loa (eye worm) hypothetical protein 0.0045 0.0174 0.0169
Toxoplasma gondii ThiF family protein 0.0033 0.0092 0.0334
Brugia malayi Receptor family ligand binding region containing protein 0.0023 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.005
Mycobacterium tuberculosis Conserved hypothetical protein 0.0035 0.0105 0.0249
Echinococcus granulosus serotonin receptor 0.0036 0.0111 0.0101
Onchocerca volvulus 0.0087 0.0441 0.0427
Loa Loa (eye worm) blistered cuticle protein 3 0.0027 0.0055 0.005
Mycobacterium leprae Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.0585 0.366 1
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0051 0.0209 0.018
Brugia malayi 6-phosphofructokinase 0.0112 0.0605 0.0605
Schistosoma mansoni protein kinase 0.0025 0.0038 0.0009
Echinococcus granulosus sumo-activating enzyme subunit 2 0.0033 0.0092 0.0082
Schistosoma mansoni sodium/chloride dependent transporter 0.0266 0.16 0.1575
Echinococcus multilocularis leukotriene A 4 hydrolase 0.0024 0.0035 0.0026
Loa Loa (eye worm) nuclear receptor NHR-67 0.0045 0.0174 0.0169
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0283 0.0675
Echinococcus granulosus neuropeptide receptor A26 0.0271 0.1631 0.1623
Toxoplasma gondii LsmAD domain-containing protein 0.0033 0.0092 0.0334
Leishmania major eukaryotic translation initiation factor-like 0.0036 0.011 0.0219
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0036 0.0111 0.0082
Trichomonas vaginalis ap endonuclease, putative 0.0029 0.0068 0.0104
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0045 0.0174 0.0145
Loa Loa (eye worm) hypothetical protein 0.0162 0.0928 0.0924
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0233 0.1387 0.1379
Schistosoma mansoni sex comb on midleg homolog 0.0087 0.0441 0.0413
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0141 0.0587
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0262 0.0233
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0036 0.0111 0.0082
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0092 0.0474 0.1179
Onchocerca volvulus Protein ultraspiracle homolog 0.0096 0.0503 0.049
Echinococcus multilocularis orexin receptor type 2 0.0036 0.0111 0.0101
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0036 0.0111 0.0082
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0036 0.0111 0.0101
Echinococcus multilocularis n acetylated alpha linked acidic dipeptidase 2 0.013 0.0723 0.0714
Brugia malayi intermediate filament protein 0.0042 0.0149 0.0149
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0099 0.0519 0.0519
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0064 0.0291 0.0263
Mycobacterium tuberculosis Conserved hypothetical protein 0.0107 0.0573 0.1532
Toxoplasma gondii histone deacetylase HDAC1 0.0092 0.0474 0.231
Plasmodium falciparum amino acid transporter, putative 0.0266 0.1598 0.8114
Echinococcus granulosus inositol monophosphatase 1 0.0043 0.0157 0.0147
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0068 0.0322 0.0312
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0035 0.0105 0.0076
Schistosoma mansoni sodium/chloride dependent transporter 0.1565 1 1
Trypanosoma brucei unspecified product 0.0024 0.0035 0.0022
Schistosoma mansoni biogenic amine receptor 0.0036 0.0111 0.0082
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0112 0.0605 0.152
Mycobacterium ulcerans hypothetical protein 0.0107 0.0573 0.1532
Loa Loa (eye worm) mbt repeat family protein 0.0087 0.0441 0.0436
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0029 0.0068 0.0126
Echinococcus granulosus thyroid hormone receptor alpha 0.0045 0.0174 0.0164
Toxoplasma gondii endonuclease IV APN 0.0079 0.0391 0.1882
Echinococcus multilocularis eukaryotic translation initiation factor 4E 0.0036 0.011 0.01
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0096 0.0503 0.0499
Echinococcus granulosus bloom syndrome protein 0.0053 0.0225 0.0215
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0157 0.0342
Schistosoma mansoni family M1 non-peptidase homologue (M01 family) 0.0044 0.0167 0.0138
Brugia malayi Dopamine receptor protein 2 0.0036 0.0111 0.0111
Schistosoma mansoni survival motor neuron protein 0.0047 0.0183 0.0154
Echinococcus granulosus leukotriene A 4 hydrolase 0.0024 0.0035 0.0026
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0605 0.1833
Loa Loa (eye worm) hypothetical protein 0.0061 0.0275 0.027
Loa Loa (eye worm) hypothetical protein 0.0037 0.0117 0.0112
Loa Loa (eye worm) hypothetical protein 0.0266 0.1598 0.1594
Toxoplasma gondii histone deacetylase HDAC2 0.0322 0.1963 1
Trypanosoma cruzi aminopeptidase, putative 0.0024 0.0035 0.0016
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0096 0.0503 0.0475
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0266 0.1598 0.159
Brugia malayi metabotropic glutamate receptor type 2 0.0023 0.0029 0.0029
Entamoeba histolytica hypothetical protein 0.0039 0.013 0.0534
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0081 0.0403 0.0403
Loa Loa (eye worm) hypothetical protein 0.0208 0.1226 0.1222
Onchocerca volvulus 0.0036 0.0111 0.0097
Echinococcus multilocularis G-protein coupled receptor, putative 0.0036 0.0111 0.0101
Brugia malayi hypothetical protein 0.0039 0.013 0.013
Brugia malayi ecdysteroid receptor 0.0096 0.0503 0.0503
Loa Loa (eye worm) hypothetical protein 0.0266 0.1598 0.1594
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Trichomonas vaginalis histone deacetylase, putative 0.0322 0.1963 0.6201
Loa Loa (eye worm) hypothetical protein 0.0096 0.0503 0.0499
Schistosoma mansoni 6-phosphofructokinase 0.0112 0.0605 0.0577
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0045 0.0174 0.0164
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0087 0.0441 0.0427
Echinococcus multilocularis 6 phosphofructokinase 0.0112 0.0605 0.0596
Leishmania major hypothetical protein, conserved 0.0033 0.0092 0.0171
Loa Loa (eye worm) hypothetical protein 0.0266 0.1598 0.1594
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0025 0.0043 0.0045
Loa Loa (eye worm) hypothetical protein 0.0158 0.0902 0.0897
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.0209 0.0209
Echinococcus multilocularis sodium and chloride dependent glycine 0.0266 0.1598 0.159
Echinococcus granulosus transcription factor Dp 1 0.0059 0.0261 0.0252
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0021 0.0014 0.0014
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.0111 0.0101
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0266 0.1598 0.1594
Leishmania major mitochondrial DNA polymerase beta 0.0312 0.1895 0.4928
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0096 0.0503 0.0494
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0025 0.0043 0.0037
Loa Loa (eye worm) hypothetical protein 0.0129 0.0712 0.0707
Echinococcus granulosus nmda type glutamate receptor 0.0023 0.0029 0.002
Brugia malayi exodeoxyribonuclease III family protein 0.0029 0.0068 0.0068
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0076 0.0311
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0036 0.0111 0.0106
Echinococcus granulosus neuropeptide receptor 0.0036 0.0111 0.0101
Echinococcus granulosus nmda type glutamate receptor 0.0062 0.0284 0.0274
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0266 0.1598 0.159
Loa Loa (eye worm) PHD-finger family protein 0.0038 0.0123 0.0118
Echinococcus multilocularis serotonin receptor 0.0091 0.0469 0.046
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0029 0.0068 0.0101
Schistosoma mansoni opsin-like receptor 0.0036 0.0111 0.0082
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0079 0.0138
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0166 0.0956 0.2583
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0096 0.0503 0.0503
Schistosoma mansoni neuropeptide F-like receptor 0.0036 0.0111 0.0082
Loa Loa (eye worm) hypothetical protein 0.0054 0.0227 0.0222
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.0209 0.0205
Echinococcus granulosus thioredoxin glutathione reductase 0.0073 0.0352 0.0342
Onchocerca volvulus 0.0036 0.0111 0.0097
Echinococcus multilocularis histone deacetylase 8 0.0092 0.0474 0.0465
Trypanosoma brucei histone deacetylase 2 0.0092 0.0474 0.118
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0036 0.0111 0.0106
Toxoplasma gondii histone deacetylase HDAC5 0.0092 0.0475 0.2312
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0043 0.0157 0.0357
Echinococcus granulosus glutamate NMDA receptor subunit 0.0122 0.0667 0.0658
Brugia malayi Bromodomain containing protein 0.0073 0.0354 0.0354
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0073 0.0355 0.035
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.0474 0.0446
Chlamydia trachomatis endonuclease IV 0.0079 0.0391 0.2319
Loa Loa (eye worm) hypothetical protein 0.0041 0.0144 0.0139
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.0605 0.2986
Schistosoma mansoni 6-phosphofructokinase 0.0112 0.0605 0.0577
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.005
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0036 0.0111 0.0101
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0031
Brugia malayi hypothetical protein 0.0021 0.0017 0.0017
Loa Loa (eye worm) glutamate receptor 0.0023 0.0029 0.0024
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0076 0.013
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0068 0.0322 0.0778
Loa Loa (eye worm) hypothetical protein 0.0311 0.1892 0.1888
Mycobacterium ulcerans DNA polymerase IV 0.0062 0.0283 0.0736
Loa Loa (eye worm) animal heme peroxidase 0.0027 0.0055 0.005
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0096 0.0503 0.0503
Onchocerca volvulus 0.0036 0.0111 0.0097
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0266 0.1598 0.1573
Brugia malayi Thioredoxin reductase 0.0073 0.0352 0.0352
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0111 0.0082
Toxoplasma gondii hypothetical protein 0.0266 0.1598 0.8114
Schistosoma mansoni zinc finger protein 0.0045 0.0174 0.0145
Onchocerca volvulus Peroxidasin homolog 0.0027 0.0055 0.0041
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0076 0.0253
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0081 0.0403 0.0374
Schistosoma mansoni histone deacetylase 1 2 3 0.0092 0.0474 0.0446
Brugia malayi photoreceptor-specific nuclear receptor 0.0096 0.0503 0.0503
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0096 0.0503 0.0494
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0027 0.0034
Echinococcus granulosus tm gpcr rhodopsin 0.0036 0.0111 0.0101
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0102 0.0538 0.1344
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0266 0.1598 0.1573
Echinococcus granulosus peroxidasin 0.0027 0.0055 0.0046
Brugia malayi putative neuropeptide receptor 0.0036 0.0111 0.0111
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0355 0.0326
Loa Loa (eye worm) hypothetical protein 0.0609 0.3817 0.3814
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Trypanosoma cruzi histone deacetylase, putative 0.0092 0.0474 0.1174
Trypanosoma brucei histone deacetylase 4 0.0092 0.0474 0.118
Trypanosoma brucei unspecified product 0.0055 0.0239 0.0559
Trypanosoma cruzi PAB1-binding protein , putative 0.0033 0.0092 0.0164
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0025 0.0043 0.0037
Plasmodium falciparum ataxin-2 like protein, putative 0.0033 0.0092 0.0334
Echinococcus granulosus glutamate receptor subunit protein glur 0.0099 0.0518 0.0509
Brugia malayi Serotonin receptor 0.0036 0.0111 0.0111
Onchocerca volvulus 0.0096 0.0503 0.049
Echinococcus granulosus survival motor neuron protein 1 0.023 0.1366 0.1358
Loa Loa (eye worm) 6-phosphofructokinase 0.0112 0.0605 0.06
Entamoeba histolytica deoxycytidyl transferase, putative 0.0035 0.0105 0.0404
Brugia malayi RNA recognition motif domain containing protein 0.0073 0.0355 0.0355
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.0653 0.4101 0.4084
Brugia malayi ImpB/MucB/SamB family protein 0.0061 0.0275 0.0275
Brugia malayi Carboxylesterase family protein 0.007 0.0332 0.0332
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0079 0.0138
Mycobacterium leprae conserved hypothetical protein 0.0138 0.077 0.2073
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0079 0.0391 0.1034
Echinococcus multilocularis neuropeptide s receptor 0.0271 0.1631 0.1623
Toxoplasma gondii thioredoxin reductase 0.0073 0.0352 0.1677
Echinococcus multilocularis neuropeptide receptor 0.0036 0.0111 0.0101
Leishmania major DNA polymerase kappa, putative 0.0042 0.0149 0.0323
Schistosoma mansoni glutamate receptor NMDA 0.0145 0.0817 0.079
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0111 0.0101
Trypanosoma brucei unspecified product 0.0024 0.0035 0.0022
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0042 0.0149 0.0323
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0034 0.01 0.009
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0111 0.0101
Brugia malayi Pre-SET motif family protein 0.0444 0.2748 0.2748
Echinococcus granulosus tm gpcr rhodopsin 0.0251 0.1506 0.1498
Echinococcus granulosus glutamate receptor 2 0.0199 0.1163 0.1155
Schistosoma mansoni terminal deoxycytidyl transferase 0.0035 0.0105 0.0076
Loa Loa (eye worm) hypothetical protein 0.0096 0.0503 0.0499
Loa Loa (eye worm) hypothetical protein 0.007 0.0332 0.0327
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.0087
Loa Loa (eye worm) RGC/RGC protein kinase 0.0025 0.0038 0.0034
Brugia malayi nuclear hormone receptor family member odr-7 0.0045 0.0174 0.0174
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0605 0.1833
Echinococcus multilocularis lamin 0.0042 0.0149 0.0139
Echinococcus multilocularis nuclear receptor nhr 48 0.0045 0.0174 0.0164
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0025 0.0043 0.0085
Brugia malayi hypothetical protein 0.0457 0.2835 0.2835
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0036 0.0111 0.0101
Loa Loa (eye worm) hypothetical protein 0.0045 0.0174 0.0169
Onchocerca volvulus 0.0036 0.0111 0.0097
Loa Loa (eye worm) neuropeptide F receptor 0.0036 0.0111 0.0106
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0045 0.0174 0.016
Echinococcus granulosus metabotropic glutamate receptor 2 0.0023 0.0029 0.002

Activities

Activity type Activity value Assay description Source Reference
-Log MIC (functional) = 0.89 Antimicrobial activity against Staphylococcus aureus after 24 hrs by two-fold serial dilution method ChEMBL. 17869511
-Log MIC (functional) = 0.89 Antimicrobial activity against Escherichia coli after 24 hrs by two-fold serial dilution method ChEMBL. 17869511
-Log MIC (functional) = 1 Antifungal activity against Aspergillus niger after 7 days by two-fold serial dilution method ChEMBL. 17869511
-Log MIC (functional) = 1.05 Antimicrobial activity against Bacillus subtilis after 24 hrs by two-fold serial dilution method ChEMBL. 17869511
-Log MIC (functional) = 1.11 Antifungal activity against Candida albicans after 2 days by two-fold serial dilution method ChEMBL. 17869511
LogP = 1.84 Partition coefficient, log P of the compound ChEMBL. 17869511
MIC (functional) = 0.89 Antimicrobial activity against Escherichia coli after 24 hrs by two-fold serial dilution method ChEMBL. 17869511
MIC (functional) = 1.11 Antifungal activity against Candida albicans after 2 days by two-fold serial dilution method ChEMBL. 17869511

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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