Detailed information for compound 460810

Basic information

Technical information
  • TDR Targets ID: 460810
  • Name: ethyl (2E,4E)-hexa-2,4-dienoate
  • MW: 140.18 | Formula: C8H12O2
  • H donors: 0 H acceptors: 1 LogP: 1.95 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)/C=C/C=C/C
  • InChi: 1S/C8H12O2/c1-3-5-6-7-8(9)10-4-2/h3,5-7H,4H2,1-2H3/b5-3+,7-6+
  • InChiKey: OZZYKXXGCOLLLO-TWTPFVCWSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2E,4E)-hexa-2,4-dienoic acid ethyl ester
  • Ethyl hexa-2,4-dienoate
  • hexa-2,4-dienoic acid ethyl ester
  • 91660-95-6
  • 2396-84-1
  • 5941-48-0
  • ZINC01648290
  • W245909_ALDRICH
  • 2,4-Hexadienoic acid, ethyl ester (9CI)
  • 2,4-Hexadienoic acid, ethyl ester, (2E,4E)-
  • 2,4-Hexadienoic acid, ethyl ester, (E,E)-
  • 2,4-Hexadienoic acid, ethyl ester, (E,E)- (9CI)
  • AI3-11732
  • EINECS 219-258-2
  • Ethyl (E,E)-2,4-hexadienoate
  • Ethyl 2,4-hexadienoate, (E,E)-
  • FEMA No. 2459
  • NSC 8874
  • 2,4-Hexadienoic acid, ethyl ester
  • Ethyl 2,4-hexadienoate
  • Ethyl sorbate
  • NSC8874
  • Sorbic acid, ethyl ester
  • InChI=1/C8H12O2/c1-3-5-6-7-8(9)10-4-2/h3,5-7H,4H2,1-2H3/b5-3+,7-6
  • 2,4-Hexadienoic acid, ethyl ester, (E,E)-)
  • Ethyl (2E,4E)-2,4-hexadienoate
  • 177687_ALDRICH
  • 85525_FLUKA
  • Ethyl trans,trans-2,4-hexadienoate

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0444 0.2748 0.2744
Schistosoma mansoni histone deacetylase hda2 0.0092 0.0474 0.0446
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0036 0.0111 0.0101
Echinococcus granulosus orexin receptor type 2 0.0036 0.0111 0.0101
Trichomonas vaginalis bromodomain-containing protein, putative 0.0048 0.0192 0.0504
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0111 0.0082
Schistosoma mansoni myosin xvIII 0.0036 0.0111 0.0082
Entamoeba histolytica hypothetical protein, conserved 0.0138 0.077 0.3839
Schistosoma mansoni adenoreceptor 0.0036 0.0111 0.0082
Onchocerca volvulus 0.0266 0.1598 0.1586
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0092 0.0474 0.0464
Schistosoma mansoni biogenic amine receptor 0.0036 0.0111 0.0082
Loa Loa (eye worm) nuclear receptor NHR-67 0.0045 0.0174 0.0169
Schistosoma mansoni blooms syndrome DNA helicase 0.0036 0.0113 0.0084
Mycobacterium leprae conserved hypothetical protein 0.0138 0.077 0.2073
Echinococcus multilocularis geminin 0.0261 0.157 0.1562
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.005
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0036 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Trypanosoma brucei ubiquitin-activating enzyme E1, putative 0.0033 0.0092 0.017
Brugia malayi Histone deacetylase family protein 0.0092 0.0474 0.0474
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0096 0.0503 0.0494
Echinococcus multilocularis fmrfamide receptor 0.0036 0.0111 0.0101
Loa Loa (eye worm) hypothetical protein 0.007 0.0331 0.0327
Trypanosoma cruzi histone deacetylase, putative 0.0092 0.0474 0.1174
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.005
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0036 0.0111 0.0101
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0045 0.0174 0.0164
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Schistosoma mansoni glutamate receptor kainate 0.0122 0.0667 0.064
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0266 0.1598 0.159
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0034 0.01 0.009
Leishmania major extracellular receptor, putative 0.0023 0.0029 0.0006
Echinococcus multilocularis glutamate receptor 2 0.0153 0.0872 0.0863
Schistosoma mansoni histamine h1 receptor 0.0036 0.0111 0.0082
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0096 0.0503 0.0503
Trichomonas vaginalis histone deacetylase, putative 0.0322 0.1963 0.6201
Schistosoma mansoni neuropeptide F-like receptor 0.0036 0.0111 0.0082
Loa Loa (eye worm) bromodomain containing protein 0.0036 0.0111 0.0107
Toxoplasma gondii exonuclease III APE 0.0029 0.0068 0.021
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0025 0.0043 0.0043
Brugia malayi mbt repeat family protein 0.0087 0.0441 0.0441
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0045 0.0174 0.0164
Leishmania major puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0024 0.0035 0.0022
Plasmodium falciparum ataxin-2 like protein, putative 0.0033 0.0092 0.0334
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.005
Brugia malayi tailless protein 0.0045 0.0174 0.0174
Loa Loa (eye worm) hypothetical protein 0.0134 0.0744 0.0739
Toxoplasma gondii ThiF family protein 0.0033 0.0092 0.0334
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0111 0.0082
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0076 0.0311
Brugia malayi Animal haem peroxidase family protein 0.0027 0.0055 0.0055
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0102 0.0538 0.2642
Schistosoma mansoni kinase 0.0047 0.0182 0.0153
Leishmania major histone deacetylase, putative 0.0322 0.1963 0.5108
Loa Loa (eye worm) hypothetical protein 0.0266 0.1598 0.1594
Loa Loa (eye worm) pip kinase 2 0.0158 0.0902 0.0897
Wolbachia endosymbiont of Brugia malayi N-acetylglucosamine-1-phosphate uridyltransferase 0.0585 0.366 1
Onchocerca volvulus 0.0081 0.0403 0.0389
Loa Loa (eye worm) leukotriene A4 hydrolase 0.0024 0.0035 0.0031
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0025 0.0043 0.0034
Echinococcus multilocularis histone deacetylase 6 0.0092 0.0474 0.0465
Schistosoma mansoni zinc finger protein 0.0045 0.0174 0.0145
Loa Loa (eye worm) hypothetical protein 0.0045 0.0174 0.0169
Brugia malayi sulfakinin receptor protein 0.0036 0.0111 0.0111
Brugia malayi Animal haem peroxidase family protein 0.0027 0.0055 0.0055
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0291 0.0263
Loa Loa (eye worm) hypothetical protein 0.1565 1 1
Echinococcus granulosus nmda type glutamate receptor 0.0062 0.0284 0.0274
Trypanosoma cruzi PAB1-binding protein , putative 0.0033 0.0092 0.0164
Brugia malayi nuclear hormone receptor 0.0045 0.0174 0.0174
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0266 0.1598 0.8114
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0036 0.0111 0.0111
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0096 0.0503 0.0494
Echinococcus granulosus SUMO activating enzyme subunit 1 0.005 0.0202 0.0192
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0096 0.0503 0.0475
Trichomonas vaginalis histone deacetylase, putative 0.0322 0.1963 0.6201
Loa Loa (eye worm) hypothetical protein 0.0158 0.0902 0.0897
Schistosoma mansoni terminal deoxycytidyl transferase 0.0035 0.0105 0.0076
Schistosoma mansoni sex comb on midleg homolog 0.0087 0.0441 0.0413
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0076 0.013
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0025 0.0043 0.0043
Echinococcus multilocularis glutamate receptor 2 0.0175 0.1014 0.1005
Schistosoma mansoni lamin 0.0042 0.0149 0.012
Schistosoma mansoni RAR-like nuclear receptor 0.0096 0.0503 0.0475
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0051 0.0209 0.018
Echinococcus granulosus 7tm_1 domain containing protein 0.0036 0.0111 0.0101
Schistosoma mansoni hypothetical protein 0.0039 0.013 0.0101
Schistosoma mansoni neuropeptide receptor 0.0036 0.0111 0.0082
Toxoplasma gondii hypothetical protein 0.0266 0.1598 0.8114
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0043 0.0157 0.039
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0048 0.0192 0.0853
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0355 0.0326
Brugia malayi acetyltransferase, GNAT family protein 0.0154 0.0875 0.0875
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0099 0.0518 0.0509
Schistosoma mansoni methyl-cpg binding protein mbd 0.0031 0.0081 0.0051
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0096 0.0503 0.0494
Onchocerca volvulus Peroxidasin homolog 0.0027 0.0055 0.0041
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0266 0.1598 0.1594
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0043 0.0157 0.039
Leishmania major eukaryotic translation initiation factor-like 0.0036 0.011 0.0219
Echinococcus granulosus eukaryotic translation initiation factor 4E 0.0036 0.011 0.01
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0029 0.0068 0.0058
Echinococcus multilocularis thioredoxin glutathione reductase 0.0073 0.0352 0.0342
Brugia malayi mbt repeat family protein 0.0087 0.0441 0.0441
Echinococcus granulosus biogenic amine 5HT receptor 0.0091 0.0469 0.046
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0283 0.0675
Schistosoma mansoni inositol monophosphatase 0.0043 0.0157 0.0128
Leishmania major histone deacetylase, putative 0.0092 0.0474 0.118
Toxoplasma gondii eukaryotic initiation factor-2B, gamma subunit, putative 0.0107 0.0573 0.2821
Echinococcus granulosus histone lysine methyltransferase setb 0.0095 0.0492 0.0483
Schistosoma mansoni glutamate receptor kainate 0.021 0.1238 0.1212
Loa Loa (eye worm) mbt repeat family protein 0.0087 0.0441 0.0436
Schistosoma mansoni protein kinase 0.0025 0.0038 0.0009
Loa Loa (eye worm) G-protein coupled receptor 0.0036 0.0111 0.0106
Mycobacterium ulcerans aminopeptidase N PepN 0.0024 0.0035 0.0057
Plasmodium vivax SUMO-activating enzyme subunit 2, putative 0.0033 0.0092 0.0334
Trichomonas vaginalis set domain proteins, putative 0.0505 0.3144 1
Treponema pallidum exodeoxyribonuclease (exoA) 0.0029 0.0068 0.0041
Schistosoma mansoni DNA polymerase eta 0.0061 0.0275 0.0247
Loa Loa (eye worm) translation initiation factor 4E 0.0036 0.011 0.0105
Echinococcus multilocularis g protein coupled receptor 0.0036 0.0111 0.0101
Plasmodium falciparum thioredoxin reductase 0.0025 0.0043 0.0085
Echinococcus granulosus histone deacetylase 3 0.0322 0.1963 0.1955
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0029 0.0068 0.0146
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0036 0.0111 0.0101
Loa Loa (eye worm) hypothetical protein 0.0035 0.0105 0.01
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.0111 0.0101
Echinococcus multilocularis thyroid hormone receptor alpha 0.0226 0.1343 0.1335
Brugia malayi hypothetical protein 0.0036 0.0111 0.0111
Plasmodium vivax histone deacetylase, putative 0.0092 0.0474 0.231
Onchocerca volvulus 0.0036 0.0111 0.0097
Trypanosoma cruzi aminopeptidase, putative 0.0024 0.0035 0.0016
Schistosoma mansoni ap endonuclease 0.0029 0.0068 0.0038
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0068 0.0322 0.0922
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0096 0.0503 0.0494
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.005
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0043 0.0157 0.067
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.005
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.005
Treponema pallidum sodium- and chloride- dependent transporter 0.1565 1 1
Echinococcus multilocularis SUMO activating enzyme subunit 1 0.005 0.0202 0.0192
Trypanosoma brucei histone deacetylase 4 0.0092 0.0474 0.118
Loa Loa (eye worm) inositol-1 0.0043 0.0157 0.0152
Brugia malayi intermediate filament protein 0.0042 0.0149 0.0149
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.005
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0111 0.0101
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0051 0.0209 0.0205
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0063 0.0287 0.0277
Brugia malayi Nuclear hormone receptor-like 1 0.0096 0.0503 0.0503
Brugia malayi follicle stimulating hormone receptor 0.0036 0.0111 0.0111
Brugia malayi glutathione reductase 0.0073 0.0352 0.0352
Schistosoma mansoni myelin transcription factor 1 myt1 0.0099 0.0519 0.0491
Brugia malayi nuclear receptor RXR 0.0045 0.0174 0.0174
Echinococcus multilocularis neuropeptides capa receptor 0.0036 0.0111 0.0101
Entamoeba histolytica hypothetical protein 0.0039 0.013 0.0534
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0096 0.0503 0.0503
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0048 0.0192 0.0853
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.005
Schistosoma mansoni hypothetical protein 0.0036 0.0111 0.0082
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0051 0.0209 0.018
Schistosoma mansoni Tata binding protein associated factor (M01 family) 0.0024 0.0035 0.0006
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0036 0.0111 0.0082
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0036 0.0111 0.0101
Schistosoma mansoni 6-phosphofructokinase 0.0112 0.0605 0.0577
Loa Loa (eye worm) hypothetical protein 0.0095 0.0492 0.0487
Plasmodium falciparum transporter, putative 0.0266 0.1598 0.8114
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0096 0.0503 0.0503
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0283 0.0675
Echinococcus multilocularis sodium and chloride dependent glycine 0.0266 0.1598 0.159
Onchocerca volvulus Histone deacetylase 10 homolog 0.0092 0.0474 0.046
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0035 0.0105 0.01
Trypanosoma cruzi histone deacetylase 1, putative 0.0322 0.1963 0.5105
Onchocerca volvulus 0.0064 0.0291 0.0277
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Schistosoma mansoni inositol monophosphatase 0.0043 0.0157 0.0128
Loa Loa (eye worm) animal heme peroxidase 0.0027 0.0055 0.005
Echinococcus multilocularis peroxidasin 0.0027 0.0055 0.0046
Echinococcus granulosus neuropeptide receptor 0.0036 0.0111 0.0101
Loa Loa (eye worm) G-protein coupled receptor 0.0036 0.0111 0.0106
Schistosoma mansoni nuclear hormone receptor 0.0045 0.0174 0.0145
Echinococcus multilocularis neuropeptide s receptor 0.0271 0.1631 0.1623
Brugia malayi Metabotropic glutamate receptor precursor. 0.0023 0.0029 0.0029
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0174 0.0446
Schistosoma mansoni hypothetical protein 0.0028 0.006 0.0031
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0025 0.0043 0.0037
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0038 0.0128 0.0311
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0023 0.0029 0.0024
Plasmodium falciparum histone deacetylase 2 0.0092 0.0474 0.231
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0025 0.0043 0.0079
Loa Loa (eye worm) hypothetical protein 0.0045 0.0174 0.0169
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0166 0.0956 0.2583
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0025 0.0043 0.0043
Loa Loa (eye worm) neuropeptide F receptor 0.0036 0.0111 0.0106
Plasmodium falciparum glutathione reductase 0.0073 0.0352 0.1677
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0262 0.0678
Schistosoma mansoni methyl-cpg binding protein mbd 0.0031 0.0081 0.0051
Loa Loa (eye worm) hypothetical protein 0.0266 0.1598 0.1594
Echinococcus multilocularis g protein coupled receptor 0.0036 0.0111 0.0101
Trypanosoma cruzi histone deacetylase 1, putative 0.0322 0.1963 0.5105
Echinococcus multilocularis carboxylesterase 5A 0.007 0.0332 0.0323
Schistosoma mansoni hypothetical protein 0.0036 0.0111 0.0082
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0068 0.0322 0.0922
Trypanosoma cruzi DNA polymerase eta, putative 0.0061 0.0275 0.0649
Schistosoma mansoni sumo-1-activating enzyme E1a 0.0045 0.0172 0.0143
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0322 0.1963 0.6201
Echinococcus multilocularis acetylcholinesterase 0.007 0.0332 0.0323
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0038 0.0123 0.0114
Schistosoma mansoni neuropeptide receptor 0.0036 0.0111 0.0082
Echinococcus multilocularis histone deacetylase 3 0.0322 0.1963 0.1955
Trypanosoma brucei trypanothione reductase 0.0073 0.0352 0.0857
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0029 0.0068 0.0126
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0029 0.0068 0.0146
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0262 0.0678
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0051 0.0209 0.02
Trypanosoma cruzi ubiquitin-activating enzyme, putative 0.0028 0.0062 0.0086
Loa Loa (eye worm) RecQ helicase 0.0053 0.0225 0.022
Brugia malayi RNA binding protein 0.0073 0.0355 0.0355
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0025 0.0043 0.0037
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0043 0.0157 0.067
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0076 0.0253
Echinococcus granulosus tm gpcr rhodopsin 0.0251 0.1506 0.1498
Trichomonas vaginalis DNA polymerase eta, putative 0.0062 0.0283 0.0795
Loa Loa (eye worm) MBCTL1 0.0099 0.0519 0.0514
Echinococcus multilocularis fmrfamide receptor 0.0036 0.0111 0.0101
Plasmodium falciparum M1-family alanyl aminopeptidase, putative 0.0024 0.0035 0.0043
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0099 0.0519 0.0509
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0029 0.0068 0.021
Brugia malayi Glutamate receptor 1 precursor 0.0175 0.1014 0.1014
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0041 0.0145 0.0116
Echinococcus granulosus nuclear factor of activated T cells 5 0.0038 0.0123 0.0114
Echinococcus multilocularis L aminoadipate semialdehyde 0.0081 0.0403 0.0393
Leishmania major eukaryotic translation initiation factor-like protein 0.0036 0.011 0.0219
Loa Loa (eye worm) ThiF family protein 0.0033 0.0092 0.0087
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0036 0.0111 0.0082
Trypanosoma cruzi ubiquitin-activating enzyme, putative 0.0033 0.0092 0.0164
Loa Loa (eye worm) hypothetical protein 0.023 0.1366 0.1362
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0151 0.0854 0.0845
Trypanosoma cruzi PAB1-binding protein , putative 0.0033 0.0092 0.0164
Brugia malayi Bromodomain containing protein 0.0073 0.0354 0.0354
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0025 0.0043 0.0105
Brugia malayi metabotropic glutamate receptor type 2 0.0023 0.0029 0.0029
Echinococcus granulosus g protein coupled receptor 0.0036 0.0111 0.0101
Onchocerca volvulus Neuropeptide F receptor homolog 0.0036 0.0111 0.0097
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0034 0.01 0.009
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0068 0.0322 0.0312
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0064 0.0291 0.0263
Echinococcus multilocularis serotonin receptor 0.0091 0.0469 0.046
Schistosoma mansoni histone deacetylase hda2 0.0092 0.0474 0.0446
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0111 0.0082
Loa Loa (eye worm) DEAH box polypeptide 35 0.0021 0.0013 0.0008
Plasmodium vivax amine transporter, putative 0.0266 0.1598 0.8114
Onchocerca volvulus 0.1565 1 1
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.013 0.072 0.0711
Mycobacterium tuberculosis Conserved hypothetical protein 0.0035 0.0105 0.0249
Brugia malayi Guanylyl cyclase protein 23 0.0025 0.0038 0.0038
Schistosoma mansoni histone deacetylase 0.0322 0.1963 0.1939
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.0024 0.0035 0.0006
Schistosoma mansoni hypothetical protein 0.0038 0.0123 0.0094
Echinococcus granulosus histone deacetylase 8 0.0092 0.0474 0.0465
Loa Loa (eye worm) hypothetical protein 0.0045 0.0174 0.0169
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0036 0.0111 0.0097
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0079 0.0391 0.0391
Brugia malayi Serotonin receptor 0.0036 0.0111 0.0111
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0045 0.0174 0.0164
Brugia malayi RE15519p 0.0036 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.005
Echinococcus granulosus neuropeptide receptor A26 0.0271 0.1631 0.1623
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0122 0.0667 0.0658
Echinococcus multilocularis somatostatin receptor 0.0036 0.0111 0.0101
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0076 0.0253
Giardia lamblia DINP protein human, muc B family 0.0042 0.0149 0.0551
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0045 0.0174 0.0174
Schistosoma mansoni lamin 0.0042 0.0149 0.012
Echinococcus multilocularis leukotriene A 4 hydrolase 0.0024 0.0035 0.0026
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0609 0.3817 1
Echinococcus granulosus geminin 0.0261 0.157 0.1562
Toxoplasma gondii histone deacetylase HDAC5 0.0092 0.0475 0.2312
Brugia malayi Receptor family ligand binding region containing protein 0.0025 0.0038 0.0038
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0036 0.0111 0.0101
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0141 0.0506
Brugia malayi hypothetical protein 0.0068 0.0322 0.0322
Brugia malayi hypothetical protein 0.0036 0.0111 0.0111
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0087 0.0441 0.0413
Mycobacterium ulcerans hypothetical protein 0.0107 0.0573 0.1532
Echinococcus granulosus acetylcholinesterase 0.007 0.0332 0.0323
Trypanosoma brucei PAB1-binding protein , putative 0.0033 0.0092 0.0171
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0266 0.1598 0.159
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0024
Trichomonas vaginalis histone deacetylase, putative 0.0322 0.1963 0.6201
Schistosoma mansoni thyroid hormone receptor 0.0226 0.1343 0.1318
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0068 0.0322 0.0293
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0044 0.0167 0.0157
Loa Loa (eye worm) aminopeptidase N 0.0068 0.0322 0.0317
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0157 0.0336
Entamoeba histolytica deoxycytidyl transferase, putative 0.0035 0.0105 0.0404
Echinococcus multilocularis glutamate receptor 4 0.0054 0.0227 0.0217
Brugia malayi hypothetical protein 0.0036 0.0111 0.0111
Brugia malayi Melatonin receptor type 1A 0.0036 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.007 0.0332 0.0327
Loa Loa (eye worm) solute carrier family 6 member 4 0.1565 1 1
Schistosoma mansoni 6-phosphofructokinase 0.0112 0.0605 0.0577
Trypanosoma brucei histone deacetylase 3 0.0092 0.0474 0.118
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0068 0.0322 0.0312
Schistosoma mansoni steroid hormone receptor ad4bp 0.0096 0.0503 0.0475
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0021 0.0014 0.0014
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0266 0.1598 0.1573
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0024 0.0035 0.0043
Plasmodium falciparum ataxin-2 like protein, putative 0.0033 0.0092 0.0334
Schistosoma mansoni opsin-like receptor 0.0036 0.0111 0.0082
Echinococcus granulosus neuropeptide s receptor 0.0271 0.1631 0.1623
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0025 0.0043 0.0014
Onchocerca volvulus 0.0045 0.0174 0.016
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0064 0.0291 0.0282
Echinococcus granulosus aminopeptidase N 0.0232 0.1381 0.1373
Schistosoma mansoni family M1 non-peptidase homologue (M01 family) 0.0044 0.0167 0.0138
Brugia malayi cytoplasmic intermediate filament protein 0.0022 0.0024 0.0024
Echinococcus granulosus dro:myosuppressin receptor 0.0036 0.0111 0.0101
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0609 0.3817 0.3817
Echinococcus multilocularis lamin dm0 0.0042 0.0149 0.0139
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0025 0.0043 0.0085
Schistosoma mansoni gamma-secretase subunit aph-1 0.0118 0.0641 0.0614
Trichomonas vaginalis histone deacetylase, putative 0.0322 0.1963 0.6201
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0096 0.0503 0.0499
Echinococcus multilocularis nmda type glutamate receptor 0.0062 0.0284 0.0274
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0079 0.0138
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0073 0.0352 0.0925
Schistosoma mansoni opsin-like receptor 0.0036 0.0111 0.0082
Leishmania major hypothetical protein, conserved 0.0028 0.006 0.0087
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0048 0.0192 0.0504
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.013 0.072 0.0711
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0266 0.1598 0.1573
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0036 0.011 0.0429
Trypanosoma brucei unspecified product 0.0024 0.0035 0.0022
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0025 0.0043 0.0045
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0041 0.0145 0.0135
Echinococcus granulosus 6 phosphofructokinase 0.0112 0.0605 0.0596
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0099 0.0519 0.0509
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0076 0.0253
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0096 0.0503 0.049
Plasmodium falciparum histone deacetylase, putative 0.0092 0.0474 0.231
Echinococcus granulosus dna polymerase eta 0.0061 0.0275 0.0266
Echinococcus granulosus alpha 1A adrenergic receptor 0.0036 0.0111 0.0101
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0262 0.0252
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0092 0.0474 0.1179
Echinococcus multilocularis dna polymerase eta 0.0061 0.0275 0.0266
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0029 0.0068 0.0101
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0034 0.01 0.0377
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.007 0.0332 0.0304
Schistosoma mansoni nuclear hormone receptor 0.0096 0.0503 0.0475
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0025 0.0043 0.0043
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0051 0.0209 0.02
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0079 0.0391 0.1882
Echinococcus multilocularis neuropeptide FF receptor 2 0.0036 0.0111 0.0101
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0076 0.0253
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Onchocerca volvulus 0.0023 0.0029 0.0015
Mycobacterium tuberculosis Probable oxidoreductase 0.0185 0.1076 0.2912
Echinococcus granulosus hypothetical protein 0.0036 0.0111 0.0101
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.005
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0025 0.0043 0.0045
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0025 0.0043 0.0043
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0038 0.0126 0.0255
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0154 0.0875 0.0866
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0034 0.01 0.0095
Trypanosoma cruzi ISWI complex protein 0.0028 0.006 0.0081
Onchocerca volvulus 0.0047 0.0183 0.0169
Echinococcus granulosus glutamate receptor 1 0.0054 0.0227 0.0217
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0096 0.0503 0.0475
Echinococcus granulosus thyroid hormone receptor alpha 0.0045 0.0174 0.0164
Echinococcus granulosus Nuclear hormone receptor HR96 0.0045 0.0174 0.0164
Brugia malayi Inositol-1 0.0043 0.0157 0.0157
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0111 0.0101
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0283 0.0675
Onchocerca volvulus 0.0036 0.0111 0.0097
Loa Loa (eye worm) hypothetical protein 0.0045 0.0174 0.0169
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0111 0.0101
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0076 0.013
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0024
Trypanosoma brucei unspecified product 0.0024 0.0035 0.0022
Loa Loa (eye worm) hypothetical protein 0.0096 0.0503 0.0499
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0061 0.0276 0.0267
Mycobacterium ulcerans molybdopterin-guanine dinucleotide biosynthesis protein A 0.0107 0.0573 0.1532
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0024
Echinococcus granulosus histone acetyltransferase MYST2 0.0099 0.0519 0.0509
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0063 0.0287 0.0686
Brugia malayi nuclear receptor RXR 0.0051 0.0209 0.0209
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0024
Loa Loa (eye worm) hypothetical protein 0.0041 0.0144 0.0139
Onchocerca volvulus Bile acid receptor homolog 0.0096 0.0503 0.049
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0079 0.0138
Schistosoma mansoni sodium-dependent amino acid transporter 0.0266 0.1598 0.1573
Onchocerca volvulus 0.0505 0.3144 0.3134
Toxoplasma gondii histone deacetylase HDAC2 0.0322 0.1963 1
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0076 0.013
Leishmania major ubiquitin-activating enzyme-like protein 0.0033 0.0092 0.017
Mycobacterium ulcerans DNA polymerase IV 0.0062 0.0283 0.0736
Onchocerca volvulus 0.0036 0.0111 0.0097
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0111 0.0101
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0183 0.0183
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0037 0.012 0.048
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Onchocerca volvulus 0.0036 0.0111 0.0097
Loa Loa (eye worm) hypothetical protein 0.0087 0.0441 0.0436
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0025 0.0043 0.0085
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0102 0.0538 0.0529
Echinococcus multilocularis acetylcholinesterase 0.007 0.0332 0.0323
Loa Loa (eye worm) hypothetical protein 0.0021 0.0014 0.001
Plasmodium falciparum glutathione reductase 0.0025 0.0043 0.0085
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0042 0.0149 0.0323
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0492 0.0464
Loa Loa (eye worm) hypothetical protein 0.0045 0.0174 0.0169
Loa Loa (eye worm) hypothetical protein 0.0266 0.1598 0.1594
Echinococcus multilocularis tyrosine kinase 0.0025 0.0038 0.0029
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0096 0.0503 0.0503
Loa Loa (eye worm) hypothetical protein 0.0081 0.0403 0.0398
Schistosoma mansoni amine GPCR 0.0036 0.0111 0.0082
Echinococcus granulosus inositol monophosphatase 1 0.0043 0.0157 0.0147
Echinococcus granulosus phosphatidylinositol 5 phosphate 4 kinase type 2 0.0158 0.0902 0.0893
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0111 0.0082
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0068 0.0322 0.0312
Brugia malayi Peroxidasin 0.0027 0.0055 0.0055
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0166 0.0956 0.2583
Plasmodium vivax ataxin-2 like protein, putative 0.0033 0.0092 0.0334
Loa Loa (eye worm) hypothetical protein 0.0034 0.01 0.0095
Echinococcus granulosus FTZ F1 alpha 0.0096 0.0503 0.0494
Loa Loa (eye worm) hypothetical protein 0.0045 0.0174 0.0169
Schistosoma mansoni bromodomain containing protein 0.0119 0.0648 0.062
Loa Loa (eye worm) hypothetical protein 0.0079 0.0391 0.0387
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0096 0.0503 0.0475
Schistosoma mansoni hypothetical protein 0.0533 0.3328 0.3309
Echinococcus granulosus ecdysone induced protein 78C 0.0096 0.0503 0.0494
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0036 0.0111 0.0101
Onchocerca volvulus 0.0027 0.0055 0.0041
Loa Loa (eye worm) hypothetical protein 0.0129 0.0712 0.0707
Echinococcus multilocularis serotonin transporter 0.1565 1 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0036 0.0111 0.0082
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0102 0.0538 0.0538
Schistosoma mansoni DNA helicase recq5 0.0034 0.01 0.0071
Loa Loa (eye worm) hypothetical protein 0.0044 0.0167 0.0162
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.0209 0.0209
Brugia malayi Dopamine receptor protein 2 0.0036 0.0111 0.0111
Trypanosoma brucei histone deacetylase 2 0.0092 0.0474 0.118
Loa Loa (eye worm) hypothetical protein 0.0061 0.0275 0.027
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0063 0.0287 0.0747
Echinococcus multilocularis eukaryotic translation initiation factor 4E 0.0036 0.011 0.01
Brugia malayi Peptidase family M1 containing protein 0.0024 0.0035 0.0035
Mycobacterium ulcerans DNA polymerase IV 0.0062 0.0283 0.0736
Schistosoma mansoni hypothetical protein 0.0045 0.0171 0.0142
Echinococcus multilocularis histone deacetylase 1 0.0322 0.1963 0.1955
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0045 0.0174 0.0164
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.0474 0.0446
Brugia malayi Peptidase family M1 containing protein 0.0232 0.1381 0.1381
Onchocerca volvulus 0.0068 0.0322 0.0308
Toxoplasma gondii histone deacetylase HDAC1 0.0092 0.0474 0.231
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0036 0.0111 0.0101
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0044 0.0163 0.0354
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0024
Echinococcus multilocularis transcription factor Dp 1 0.0059 0.0261 0.0252
Brugia malayi hypothetical protein 0.0051 0.0209 0.0209
Loa Loa (eye worm) RGC/RGC protein kinase 0.0025 0.0038 0.0034
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.013 0.0121
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0348 0.2129 0.2121
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0029 0.0068 0.0063
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0034 0.01 0.0377
Loa Loa (eye worm) hypothetical protein 0.0051 0.0209 0.0205
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0034 0.01 0.01
Echinococcus multilocularis serotonin receptor 0.0091 0.0469 0.046
Loa Loa (eye worm) steroid hormone receptor 0.0096 0.0503 0.0499
Loa Loa (eye worm) hypothetical protein 0.0096 0.0503 0.0499
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0283 0.0669
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0036 0.0111 0.0082
Echinococcus multilocularis FTZ F1 alpha 0.0096 0.0503 0.0494
Echinococcus multilocularis histone deacetylase 0.0092 0.0474 0.0465
Loa Loa (eye worm) 6-phosphofructokinase 0.0112 0.0605 0.06
Brugia malayi nuclear hormone receptor 0.0096 0.0503 0.0503
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0474 0.141
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Onchocerca volvulus 0.0042 0.0149 0.0135
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0099 0.0519 0.0519
Plasmodium vivax histone deacetylase 1, putative 0.0322 0.1963 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Brugia malayi TAR-binding protein 0.0073 0.0355 0.0355
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0036 0.011 0.024
Loa Loa (eye worm) hypothetical protein 0.0266 0.1598 0.1594
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0076 0.0253
Loa Loa (eye worm) hypothetical protein 0.0045 0.0174 0.0169
Toxoplasma gondii hypothetical protein 0.005 0.0205 0.0919
Schistosoma mansoni eukaryotic translation initiation factor 4e 0.0036 0.011 0.0081
Echinococcus multilocularis neuropeptide receptor 0.0036 0.0111 0.0101
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0283 0.0675
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.013 0.0121
Loa Loa (eye worm) histone deacetylase 0.0092 0.0474 0.047
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0045 0.0174 0.016
Schistosoma mansoni zinc finger protein 0.0039 0.0134 0.0105
Mycobacterium tuberculosis Conserved protein 0.0138 0.077 0.2073
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0105 0.0105
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0605 0.1833
Schistosoma mansoni ubiquitin-activating enzyme E1b 0.0033 0.0092 0.0062
Brugia malayi hypothetical protein 0.0045 0.0174 0.0174
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0024 0.0035 0.0016
Trichomonas vaginalis inositol monophosphatase, putative 0.0043 0.0157 0.039
Brugia malayi Thioredoxin reductase 0.0073 0.0352 0.0352
Onchocerca volvulus 0.0266 0.1598 0.1586
Trypanosoma brucei Eukaryotic translation initiation factor 4E-1 0.0036 0.011 0.0219
Schistosoma mansoni ATP-binding cassette transporter 0.0122 0.0667 0.064
Trypanosoma brucei DNA polymerase IV, putative 0.0062 0.0283 0.0675
Loa Loa (eye worm) melatonin receptor type 1A 0.0036 0.0111 0.0106
Echinococcus multilocularis neuropeptides capa receptor 0.0036 0.0111 0.0101
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0025 0.0043 0.0043
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0068 0.0322 0.0778
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0024
Loa Loa (eye worm) acetyltransferase 0.0154 0.0875 0.087
Leishmania major histone deacetylase, putative 0.0322 0.1963 0.5108
Trichomonas vaginalis DNA helicase recq, putative 0.0038 0.0126 0.0291
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0266 0.1598 0.159
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0044 0.0163 0.036
Brugia malayi Nuclear hormone receptor-like 1 0.0051 0.0209 0.0209
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0036 0.0111 0.0082
Loa Loa (eye worm) hypothetical protein 0.0025 0.0038 0.0034
Toxoplasma gondii LsmAD domain-containing protein 0.0033 0.0092 0.0334
Brugia malayi nuclear receptor NHR-88 0.0045 0.0174 0.0174
Echinococcus granulosus glutamate NMDA receptor subunit 0.0122 0.0667 0.0658
Loa Loa (eye worm) RGC/RGC protein kinase 0.0025 0.0038 0.0034
Echinococcus multilocularis dna polymerase kappa 0.0062 0.0283 0.0273
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0025 0.0043 0.0085
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0102 0.0538 0.1344
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0023 0.0029 0.0029
Onchocerca volvulus 0.0036 0.0111 0.0097
Trypanosoma cruzi histone deacetylase, putative 0.0092 0.0474 0.1174
Brugia malayi nuclear hormone receptor family member nhr-6 0.0045 0.0174 0.0174
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Trypanosoma cruzi Aminopeptidase M1, putative 0.0068 0.0322 0.0772
Onchocerca volvulus 0.0087 0.0441 0.0427
Onchocerca volvulus 0.0036 0.0111 0.0097
Trypanosoma brucei DNA polymerase IV, putative 0.0055 0.0239 0.0559
Echinococcus granulosus neuropeptides capa receptor 0.0036 0.0111 0.0101
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0036 0.0111 0.0101
Trypanosoma brucei unspecified product 0.0055 0.0239 0.0559
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0068 0.0322 0.0778
Brugia malayi photoreceptor-specific nuclear receptor 0.0096 0.0503 0.0503
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.1565 1 1
Trypanosoma brucei DNA polymerase IV, putative 0.0062 0.0283 0.0675
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0112 0.0605 0.162
Brugia malayi conserved hypotetical protein 0.0045 0.0174 0.0174
Loa Loa (eye worm) hypothetical protein 0.0091 0.0469 0.0465
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0025 0.0043 0.0079
Mycobacterium tuberculosis Probable reductase 0.0166 0.0956 0.2583
Schistosoma mansoni survival motor neuron protein 0.0047 0.0183 0.0154
Loa Loa (eye worm) glutathione reductase 0.0073 0.0352 0.0347
Schistosoma mansoni neuropeptide f receptor 76f 0.0036 0.0111 0.0082
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0032 0.0087 0.031
Echinococcus multilocularis survival motor neuron protein 1 0.023 0.1366 0.1358
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0096 0.0503 0.0499
Onchocerca volvulus 0.0036 0.0111 0.0097
Schistosoma mansoni amine GPCR 0.0036 0.0111 0.0082
Brugia malayi ImpB/MucB/SamB family protein 0.0061 0.0275 0.0275
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.0585 0.366 1
Schistosoma mansoni nuclear receptor nhr-48 0.0045 0.0174 0.0145
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Brugia malayi G-protein coupled receptor 0.0036 0.0111 0.0111
Brugia malayi Nuclear hormone receptor E75 0.0045 0.0174 0.0174
Schistosoma mansoni hypothetical protein 0.0261 0.157 0.1545
Brugia malayi G protein-coupled receptor F59B2.13 0.0036 0.0111 0.0111
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0036 0.0111 0.0101
Onchocerca volvulus 0.0036 0.0111 0.0097
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0073 0.0355 0.035
Loa Loa (eye worm) hypothetical protein 0.0096 0.0503 0.0499
Brugia malayi hypothetical protein 0.0036 0.0111 0.0111
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0031 0.0081 0.0071
Echinococcus multilocularis nmda type glutamate receptor 0.0023 0.0029 0.002
Brugia malayi hypothetical protein 0.0036 0.0111 0.0111
Mycobacterium leprae Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.0585 0.366 1
Echinococcus multilocularis histone acetyltransferase MYST2 0.0099 0.0519 0.0509
Echinococcus granulosus neuropeptide receptor 0.0036 0.0111 0.0101
Loa Loa (eye worm) hypothetical protein 0.0164 0.0939 0.0935
Brugia malayi Intermediate filament tail domain containing protein 0.0042 0.0149 0.0149
Trichomonas vaginalis ap endonuclease, putative 0.0029 0.0068 0.0104
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0266 0.1598 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Echinococcus granulosus glutamate receptor subunit protein glur 0.0099 0.0518 0.0509
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0076 0.0049
Schistosoma mansoni hypothetical protein 0.013 0.072 0.0692
Echinococcus granulosus polycomb protein SCMH1 0.0087 0.0441 0.0432
Echinococcus granulosus allatostatin A receptor 0.0036 0.0111 0.0101
Leishmania major hypothetical protein, conserved 0.0033 0.0092 0.0171
Loa Loa (eye worm) hypothetical protein 0.0266 0.1598 0.1594
Brugia malayi neuropeptide F receptor 0.0036 0.0111 0.0111
Trypanosoma cruzi ISWI complex protein 0.0028 0.006 0.0081
Echinococcus multilocularis tar DNA binding protein 0.0073 0.0355 0.0345
Schistosoma mansoni nuclear receptor 0.0045 0.0174 0.0145
Loa Loa (eye worm) hypothetical protein 0.0045 0.0174 0.0169
Brugia malayi exodeoxyribonuclease III family protein 0.0029 0.0068 0.0068
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0605 0.1833
Echinococcus granulosus dna polymerase kappa 0.0062 0.0283 0.0273
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0096 0.0503 0.0494
Echinococcus granulosus neuropeptide Y receptor 0.0036 0.0111 0.0101
Echinococcus multilocularis g protein coupled receptor 0.0036 0.0111 0.0101
Onchocerca volvulus 0.0036 0.0111 0.0097
Echinococcus granulosus intermediate filament protein 0.0042 0.0149 0.0139
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0035 0.0105 0.0096
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0102 0.0538 0.0511
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0249 0.1487 0.1478
Brugia malayi polk-prov protein 0.0038 0.0127 0.0127
Echinococcus granulosus gamma secretase subunit aph 1 0.0118 0.0641 0.0632
Loa Loa (eye worm) hypothetical protein 0.1565 1 1
Trichomonas vaginalis DNA helicase recq, putative 0.0053 0.0225 0.061
Brugia malayi ThiF family protein 0.005 0.0202 0.0202
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0096 0.0503 0.0503
Loa Loa (eye worm) hypothetical protein 0.0266 0.1598 0.1594
Brugia malayi hypothetical protein 0.0036 0.0111 0.0111
Loa Loa (eye worm) histone deacetylase 3 0.0322 0.1963 0.1959
Toxoplasma gondii histone deacetylase HDAC4 0.0092 0.0474 0.231
Echinococcus multilocularis aminopeptidase N 0.0232 0.1381 0.1373
Onchocerca volvulus 0.0027 0.0055 0.0041
Loa Loa (eye worm) animal heme peroxidase 0.0027 0.0055 0.005
Echinococcus multilocularis bloom syndrome protein 0.0053 0.0225 0.0215
Brugia malayi Animal haem peroxidase family protein 0.0027 0.0055 0.0055
Loa Loa (eye worm) DR-78 0.0045 0.0174 0.0169
Loa Loa (eye worm) hypothetical protein 0.0162 0.0928 0.0924
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0154 0.0875 0.0848
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0166 0.0956 0.2583
Loa Loa (eye worm) hypothetical protein 0.0096 0.0503 0.0499
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0262 0.0233
Schistosoma mansoni hypothetical protein 0.0036 0.0111 0.0082
Loa Loa (eye worm) hypothetical protein 0.0044 0.0167 0.0162
Brugia malayi Pre-SET motif family protein 0.0064 0.0291 0.0291
Leishmania major DNA polymerase kappa, putative 0.0042 0.0149 0.0323
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0036 0.0111 0.0101
Loa Loa (eye worm) hypothetical protein 0.0096 0.0503 0.0499
Trypanosoma brucei ISWI complex protein 0.0028 0.006 0.0087
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0096 0.0503 0.0503
Entamoeba histolytica serine/threonine protein kinase, putative 0.0092 0.0474 0.2308
Loa Loa (eye worm) hypothetical protein 0.0045 0.0174 0.0169
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0112 0.0606 0.0597
Echinococcus granulosus Nuclear hormone receptor HR96 0.0045 0.0174 0.0164
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0036 0.0111 0.0082
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0036 0.0111 0.0101
Echinococcus granulosus peroxidasin 0.0027 0.0055 0.0046
Echinococcus granulosus histone deacetylase 1 0.0322 0.1963 0.1955
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0079 0.0391 0.1034
Brugia malayi histone deacetylase 11 0.0092 0.0474 0.0474
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0112 0.0605 0.152
Mycobacterium ulcerans 6-phosphofructokinase 0.0112 0.0605 0.162
Trypanosoma cruzi histone deacetylase, putative 0.0092 0.0474 0.1174
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0127 0.0265
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Trichomonas vaginalis DNA helicase recq1, putative 0.0053 0.0225 0.061
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Loa Loa (eye worm) norepinephrine transporter 0.1565 1 1
Echinococcus granulosus bloom syndrome protein 0.0053 0.0225 0.0215
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0096 0.0503 0.0494
Plasmodium vivax ubiquitin activating enzyme, putative 0.005 0.0202 0.0902
Schistosoma mansoni histone deacetylase 1 2 3 0.0092 0.0474 0.0446
Schistosoma mansoni thyroid hormone receptor 0.0226 0.1343 0.1318
Echinococcus granulosus leukotriene A 4 hydrolase 0.0024 0.0035 0.0026
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0043 0.0157 0.0357
Loa Loa (eye worm) hypothetical protein 0.0096 0.0503 0.0499
Schistosoma mansoni amine GPCR 0.0036 0.0111 0.0082
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0474 0.141
Brugia malayi hypothetical protein 0.0024 0.0035 0.0035
Brugia malayi 6-phosphofructokinase 0.0112 0.0605 0.0605
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0036 0.0111 0.0106
Leishmania major trypanothione reductase 0.0073 0.0352 0.0857
Loa Loa (eye worm) hypothetical protein 0.0045 0.0174 0.0169
Brugia malayi hypothetical protein 0.0457 0.2835 0.2835
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0076 0.013
Brugia malayi hypothetical protein 0.0039 0.013 0.013
Brugia malayi larval opioid receptor 0.0036 0.0111 0.0111
Brugia malayi hypothetical protein 0.0036 0.0111 0.0111
Echinococcus granulosus serotonin receptor 0.0036 0.0111 0.0101
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0198 0.1157 0.1149
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0025 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0605 0.1833
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0023 0.0029 0.0024
Plasmodium falciparum thioredoxin reductase 0.0073 0.0352 0.1677
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0029 0.0068 0.0101
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.0111 0.0101
Brugia malayi hypothetical protein 0.0051 0.0209 0.0209
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0355 0.0326
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0157 0.0342
Brugia malayi Bloom's syndrome protein homolog 0.0053 0.0225 0.0225
Loa Loa (eye worm) hypothetical protein 0.0051 0.0209 0.0205
Brugia malayi hypothetical protein 0.0036 0.0111 0.0111
Entamoeba histolytica histone deacetylase, putative 0.0322 0.1963 1
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0027 0.0034
Echinococcus granulosus zinc finger protein 0.0039 0.0134 0.0124
Onchocerca volvulus Peroxidasin homolog 0.0027 0.0055 0.0041
Brugia malayi G-protein coupled receptor 0.0036 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0051 0.0209 0.0205
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0474 0.141
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0079 0.0391 0.1882
Onchocerca volvulus 0.0036 0.0111 0.0097
Plasmodium vivax hypothetical protein, conserved 0.0266 0.1598 0.8114
Brugia malayi Pre-SET motif family protein 0.0444 0.2748 0.2748
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0038 0.0126 0.0261
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0312 0.1895 0.4925
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0163 0.0354
Schistosoma mansoni growth hormone secretagogue receptor 0.0036 0.0111 0.0082
Trypanosoma brucei aminopeptidase, putative 0.0024 0.0035 0.0022
Echinococcus granulosus neuropeptide Y receptor 0.0036 0.0111 0.0101
Schistosoma mansoni amine GPCR 0.0528 0.3295 0.3275
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0081 0.0403 0.0403
Echinococcus granulosus fetal alzheimer antigen falz 0.0041 0.0145 0.0135
Leishmania major C-8 sterol isomerase-like protein 0.0609 0.3817 1
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0266 0.1598 0.159
Echinococcus multilocularis n acetylated alpha linked acidic dipeptidase 2 0.013 0.0723 0.0714
Echinococcus granulosus sumo-activating enzyme subunit 2 0.0033 0.0092 0.0082
Brugia malayi ThiF family protein 0.0033 0.0092 0.0092
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0096 0.0503 0.0494
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0025 0.0043 0.0037
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0233 0.1387 0.1379
Loa Loa (eye worm) 6-phosphofructokinase 0.0112 0.0605 0.06
Brugia malayi hypothetical protein 0.0036 0.0111 0.0111
Schistosoma mansoni coup transcription factor 0.0096 0.0503 0.0475
Echinococcus granulosus acetylcholinesterase 0.007 0.0332 0.0323
Echinococcus granulosus atrial natriuretic peptide receptor 0.0023 0.0029 0.002
Trichomonas vaginalis glutathione reductase, putative 0.0025 0.0043 0.0026
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0024 0.0035 0.0016
Chlamydia trachomatis endonuclease IV 0.0079 0.0391 0.2319
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0199 0.1163 0.1155
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.013 0.0101
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0068 0.0322 0.0312
Trypanosoma brucei histone deacetylase 1 0.0322 0.1963 0.5108
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0283 0.0675
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0102 0.0538 0.135
Brugia malayi RNA recognition motif domain containing protein 0.0073 0.0355 0.0355
Echinococcus granulosus SAM and MBT domain containing protein 0.0087 0.0441 0.0432
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0141 0.0587
Loa Loa (eye worm) phosphofructokinase 0.0112 0.0605 0.06
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0036 0.011 0.024
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0023 0.0029 0.002
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0034 0.01 0.0377
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.005
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0043 0.0157 0.039
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0266 0.1598 0.159
Entamoeba histolytica hypothetical protein 0.0039 0.013 0.0534
Echinococcus granulosus tyrosine kinase 0.0025 0.0038 0.0029
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0036 0.0111 0.0101
Schistosoma mansoni DNA helicase recq1 0.0034 0.01 0.0071
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.0653 0.4101 0.4084
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0266 0.1598 0.1598
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0042 0.0149 0.037
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Schistosoma mansoni histone deacetylase 4 5 0.0092 0.0474 0.0446
Onchocerca volvulus 0.0036 0.0111 0.0097
Echinococcus multilocularis G-protein coupled receptor, putative 0.0036 0.0111 0.0101
Mycobacterium ulcerans hypothetical protein 0.0164 0.0941 0.2542
Brugia malayi hypothetical protein 0.0023 0.0029 0.0029
Echinococcus granulosus histone deacetylase 6 0.0092 0.0474 0.0465
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0096 0.0503 0.0503
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0474 0.141
Brugia malayi ImpB/MucB/SamB family protein 0.0035 0.0105 0.0105
Brugia malayi orphan nuclear receptor NR2E1 0.0045 0.0174 0.0174
Brugia malayi GnHR receptor homolog 0.0036 0.0111 0.0111
Trypanosoma cruzi histone deacetylase, putative 0.0092 0.0474 0.1174
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0474 0.141
Loa Loa (eye worm) hypothetical protein 0.0045 0.0174 0.0169
Brugia malayi G protein-coupled receptor 0.0036 0.0111 0.0111
Toxoplasma gondii hypothetical protein 0.0266 0.1598 0.8114
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0027 0.0034
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0063 0.0287 0.0277
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0163 0.0354
Echinococcus granulosus g-protein coupled receptor 0.0036 0.0111 0.0101
Mycobacterium ulcerans hypothetical protein 0.0138 0.077 0.2073
Loa Loa (eye worm) hypothetical protein 0.0092 0.0474 0.047
Echinococcus multilocularis zinc finger protein 0.0039 0.0134 0.0124
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.0111 0.0101
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0008
Brugia malayi nuclear hormone receptor family member odr-7 0.0045 0.0174 0.0174
Echinococcus multilocularis nuclear receptor nhr 48 0.0045 0.0174 0.0164
Plasmodium vivax histone deacetylase, putative 0.0092 0.0474 0.231
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0262 0.0252
Trypanosoma cruzi trypanothione reductase, putative 0.0025 0.0043 0.0037
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0029 0.0068 0.0112
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0034 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0605 0.1833
Entamoeba histolytica aminopeptidase, putative 0.0068 0.0322 0.1524
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0474 0.141
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0266 0.1598 0.1573
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0068 0.0322 0.0312
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.0111 0.0101
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0096 0.0503 0.0499
Schistosoma mansoni glutamate receptor NMDA 0.0145 0.0817 0.079
Echinococcus granulosus histone acetyltransferase KAT2B 0.0145 0.082 0.0811
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0092 0.0474 0.0464
Echinococcus multilocularis histone deacetylase 6 0.0092 0.0474 0.0465
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0312 0.1895 0.4925
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0266 0.1598 0.159
Plasmodium vivax histone deacetylase 2, putative 0.0092 0.0474 0.231
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0096 0.0503 0.0494
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0233 0.1387 0.1379
Brugia malayi Histone deacetylase 1 0.0322 0.1963 0.1963
Brugia malayi translation initiation factor 4E 0.0036 0.011 0.011
Loa Loa (eye worm) acetylcholinesterase 1 0.007 0.0332 0.0327
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0036 0.0111 0.0101
Loa Loa (eye worm) hypothetical protein 0.002 0.001 0.0005
Mycobacterium ulcerans aminopeptidase N PepN 0.0068 0.0322 0.0844
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0147 0.0833 0.2128
Echinococcus granulosus peptide allatostatin:somatostatin 0.0036 0.0111 0.0101
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0025 0.0043 0.0037
Schistosoma mansoni sodium/chloride dependent transporter 0.0266 0.16 0.1575
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0112 0.0605 0.162
Brugia malayi ORL1-like opioid receptor 0.0036 0.0111 0.0111
Brugia malayi TATA binding protein associated factor 0.0024 0.0035 0.0035
Trypanosoma brucei polo-like protein kinase 0.0092 0.0474 0.1179
Brugia malayi hypothetical protein 0.0033 0.0092 0.0092
Echinococcus granulosus lamin dm0 0.0042 0.0149 0.0139
Schistosoma mansoni glutamate receptor AMPA 0.0122 0.0667 0.064
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Echinococcus multilocularis neuropeptide Y receptor 0.0036 0.0111 0.0101
Loa Loa (eye worm) hypothetical protein 0.0078 0.0383 0.0378
Loa Loa (eye worm) TYRA-2 protein 0.0036 0.0111 0.0106
Brugia malayi Steroid receptor seven-up type 2 0.0096 0.0503 0.0503
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0158 0.0902 0.0875
Onchocerca volvulus 0.0457 0.2835 0.2824
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0111 0.0082
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0036 0.011 0.024
Trypanosoma cruzi Aph-1 protein, putative 0.0046 0.0177 0.0389
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0068 0.0322 0.0312
Echinococcus granulosus neuropeptides capa receptor 0.0036 0.0111 0.0101
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0111 0.0101
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.0605 0.2986
Onchocerca volvulus Chorion peroxidase homolog 0.0027 0.0055 0.0041
Giardia lamblia Histone deacetylase 0.0322 0.1963 1
Loa Loa (eye worm) runx1 0.0057 0.0251 0.0246
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0266 0.1598 0.1573
Echinococcus multilocularis orexin receptor type 2 0.0036 0.0111 0.0101
Mycobacterium tuberculosis Conserved hypothetical protein 0.0138 0.077 0.2073
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0102 0.0538 0.0529
Echinococcus multilocularis NMDA receptor 0.0133 0.0742 0.0733
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0034 0.01 0.009
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0036 0.0111 0.0101
Echinococcus multilocularis dro:myosuppressin receptor 0.0036 0.0111 0.0101
Loa Loa (eye worm) neuropeptide F receptor 0.0036 0.0111 0.0106
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.0111 0.0101
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0045 0.0174 0.016
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0025 0.0038 0.0024
Loa Loa (eye worm) thioredoxin reductase 0.0073 0.0352 0.0347
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Loa Loa (eye worm) hypothetical protein 0.0096 0.0503 0.0499
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0033 0.0091 0.0332
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0036 0.011 0.0429
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0029 0.0068 0.0107
Echinococcus granulosus histone deacetylase 6 0.0092 0.0474 0.0465
Brugia malayi Bromodomain containing protein 0.014 0.0786 0.0786
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0045 0.0174 0.0164
Echinococcus granulosus methyl CpG binding domain protein 2 0.0031 0.0081 0.0071
Schistosoma mansoni ap endonuclease 0.0029 0.0068 0.0038
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0158 0.0902 0.0875
Brugia malayi ecdysteroid receptor 0.0096 0.0503 0.0503
Echinococcus granulosus G protein coupled receptor 139 0.0036 0.0111 0.0101
Echinococcus multilocularis neuropeptide receptor 0.0036 0.0111 0.0101
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0111 0.0101
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0029 0.0068 0.021
Schistosoma mansoni biogenic amine (5HT) receptor 0.0036 0.0111 0.0082
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0076 0.0311
Schistosoma mansoni amine GPCR 0.0036 0.0111 0.0082
Loa Loa (eye worm) PHD-finger family protein 0.0038 0.0123 0.0118
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0262 0.0619
Echinococcus multilocularis neuropeptide receptor A26 0.0271 0.1631 0.1623
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0024 0.0035 0.0043
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0266 0.1598 0.8114
Brugia malayi hypothetical protein 0.0021 0.0017 0.0017
Brugia malayi Serotonin receptor 0.0036 0.0111 0.0111
Echinococcus granulosus histone deacetylase 6 0.0092 0.0474 0.0465
Brugia malayi Dopamine receptor 0.0036 0.0111 0.0111
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0036 0.0111 0.0082
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0038 0.0128 0.0311
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0036 0.0111 0.0111
Brugia malayi Pip kinase protein 2 0.0158 0.0902 0.0902
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0036 0.0111 0.0101
Brugia malayi ecdysone receptor 0.0045 0.0174 0.0174
Echinococcus granulosus survival motor neuron protein 1 0.023 0.1366 0.1358
Echinococcus multilocularis histone deacetylase 6 0.0092 0.0474 0.0465
Loa Loa (eye worm) glutamate receptor 0.0023 0.0029 0.0024
Onchocerca volvulus 0.0036 0.0111 0.0097
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0024 0.0035 0.0016
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0027 0.0034
Schistosoma mansoni histone deacetylase 4 5 0.0092 0.0474 0.0446
Echinococcus granulosus tar DNA binding protein 0.0073 0.0355 0.0345
Echinococcus multilocularis g-protein coupled receptor 0.0036 0.0111 0.0101
Treponema pallidum NADH oxidase 0.0025 0.0043 0.0017
Loa Loa (eye worm) hypothetical protein 0.007 0.0332 0.0327
Echinococcus granulosus fmrfamide receptor 0.0036 0.0111 0.0101
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0025 0.0043 0.0037
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0036 0.0111 0.0101
Loa Loa (eye worm) hypothetical protein 0.0054 0.0227 0.0222
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0111 0.0082
Echinococcus multilocularis histone deacetylase 7 0.0092 0.0474 0.0465
Toxoplasma gondii aminopeptidase n, putative 0.0024 0.0035 0.0043
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0096 0.0503 0.0475
Mycobacterium ulcerans hypothetical protein 0.0138 0.077 0.2073
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0076 0.013
Brugia malayi hypothetical protein 0.0266 0.1598 0.1598
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0322 0.1963 0.6201
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0024 0.0035 0.0026
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0111 0.0101
Toxoplasma gondii hypothetical protein 0.005 0.0202 0.0902
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0266 0.1598 0.1598
Giardia lamblia Sgs1 DNA helicase, putative 0.0034 0.01 0.0295
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0068 0.0322 0.0312
Echinococcus multilocularis inositol monophosphatase 1 0.0043 0.0157 0.0147
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0025 0.0043 0.0037
Schistosoma mansoni nuclear receptor 0.0045 0.0174 0.0145
Trypanosoma brucei Aminopeptidase M1, putative 0.0068 0.0322 0.0778
Brugia malayi Probable ATP-dependent helicase DHX35 0.0021 0.0013 0.0013
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0233 0.1387 0.1379
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0149 0.0323
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.0225 0.0517
Brugia malayi hypothetical protein 0.0027 0.0055 0.0055
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0029 0.0068 0.021
Loa Loa (eye worm) hypothetical protein 0.0033 0.0092 0.0087
Leishmania major mitochondrial DNA polymerase beta 0.0312 0.1895 0.4928
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0096 0.0503 0.0494
Loa Loa (eye worm) hypothetical protein 0.0051 0.0209 0.0205
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0096 0.0503 0.0503
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0025 0.0043 0.0037
Brugia malayi 6-phosphofructokinase 0.0112 0.0605 0.0605
Trypanosoma cruzi aminopeptidase, putative 0.0068 0.0322 0.0772
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0322 0.1963 0.6201
Onchocerca volvulus 0.0024 0.0035 0.0021
Echinococcus multilocularis receptor type guanylyl cyclase 0.0025 0.0038 0.0029
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0133 0.0742 0.0733
Echinococcus granulosus metabotropic glutamate receptor 5 0.0023 0.0029 0.002
Schistosoma mansoni biogenic amine receptor 0.0036 0.0111 0.0082
Brugia malayi Receptor family ligand binding region containing protein 0.0023 0.0029 0.0029
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0111 0.0082
Echinococcus granulosus sex peptide receptor 0.0036 0.0111 0.0101
Brugia malayi Animal haem peroxidase family protein 0.0027 0.0055 0.0055
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0025 0.0043 0.0043
Echinococcus multilocularis glutamate receptor 2 0.0199 0.1163 0.1155
Toxoplasma gondii aminopeptidase N, putative 0.0024 0.0035 0.0043
Onchocerca volvulus 0.0036 0.0111 0.0097
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0266 0.1598 0.1598
Schistosoma mansoni histone deacetylase 0.0322 0.1963 0.1939
Brugia malayi Blistered cuticle protein 3 0.0027 0.0055 0.0055
Trichomonas vaginalis histone deacetylase, putative 0.0322 0.1963 0.6201
Schistosoma mansoni sodium/chloride dependent transporter 0.0266 0.1598 0.1573
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0166 0.0956 0.2583
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0133 0.0742 0.0733
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0348 0.2129 0.2121
Echinococcus granulosus nmda type glutamate receptor 0.0023 0.0029 0.002
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0096 0.0503 0.0503
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0068 0.0322 0.0293
Loa Loa (eye worm) serotonin transporter b 0.1565 1 1
Loa Loa (eye worm) animal heme peroxidase 0.0027 0.0055 0.005
Schistosoma mansoni sex comb on midleg homolog 0.0087 0.0441 0.0413
Loa Loa (eye worm) histone deacetylase 11 0.0092 0.0474 0.047
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0042 0.0149 0.0144
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.0111 0.0101
Mycobacterium tuberculosis Probable dehydrogenase 0.0166 0.0956 0.2583
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.0209 0.0205
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0035 0.0105 0.0096
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0055 0.0237 0.0232
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0118 0.0641 0.0637
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0031
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.0605 0.2986
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0068 0.0322 0.0312
Mycobacterium ulcerans bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 0.0585 0.366 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0283 0.0675
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0022 0.0024 0.0019
Onchocerca volvulus 0.0025 0.0038 0.0024
Trichomonas vaginalis histone deacetylase, putative 0.0322 0.1963 0.6201
Plasmodium vivax SET domain protein, putative 0.0064 0.0291 0.1365
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0233 0.1387 0.1379
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0036 0.0111 0.0106
Onchocerca volvulus Dual oxidase homolog 0.0027 0.0055 0.0041
Loa Loa (eye worm) hypothetical protein 0.0099 0.0519 0.0514
Onchocerca volvulus 0.0036 0.0111 0.0097
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0266 0.1598 0.1598
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0141 0.0587
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.005
Schistosoma mansoni sumo-1-activating enzyme E1a 0.005 0.0202 0.0173
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0283 0.0675
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0023 0.0029 0.002
Brugia malayi Glutamate receptor 2 precursor 0.0175 0.1014 0.1014
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0023 0.0029 0.002
Schistosoma mansoni peroxidasin 0.0027 0.0055 0.0026
Echinococcus granulosus histone acetyltransferase KAT2B 0.0048 0.0192 0.0183
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0096 0.0503 0.0503
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0133 0.0742 0.0733
Echinococcus granulosus somatostatin receptor 0.0036 0.0111 0.0101
Onchocerca volvulus 0.0158 0.0902 0.0888
Schistosoma mansoni biogenic amine (5HT) receptor 0.0091 0.0469 0.0441
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0036 0.0111 0.0106
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0036 0.0111 0.0101
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0081 0.0403 0.0374
Loa Loa (eye worm) hypothetical protein 0.0081 0.0405 0.0401
Echinococcus multilocularis allatostatin A receptor 0.0036 0.0111 0.0101
Echinococcus granulosus sodium and chloride dependent glycine 0.0266 0.1598 0.159
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0283 0.0669
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0062 0.0283 0.0795
Echinococcus multilocularis ecdysone induced protein 78C 0.0096 0.0503 0.0494
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0262 0.0678
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0096 0.0503 0.0499
Leishmania major DNA polymerase eta, putative 0.0061 0.0275 0.0655
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0096 0.0503 0.0475
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0355 0.0326
Brugia malayi Carboxylesterase family protein 0.007 0.0332 0.0332
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0045 0.0174 0.0145
Schistosoma mansoni neuropeptide receptor 0.0036 0.0111 0.0082
Plasmodium vivax glutathione reductase, putative 0.0073 0.0352 0.1677
Loa Loa (eye worm) hypothetical protein 0.0091 0.0469 0.0465
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0036 0.0111 0.0082
Loa Loa (eye worm) hypothetical protein 0.0042 0.0149 0.0144
Schistosoma mansoni NAALADASE L peptidase (M28 family) 0.0085 0.0433 0.0404
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0096 0.0503 0.0494
Schistosoma mansoni intermediate filament proteins 0.0042 0.0149 0.012
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0076 0.0169
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0283 0.0669
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0266 0.1598 0.1573
Trypanosoma cruzi polo-like protein kinase, putative 0.0092 0.0474 0.1173
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0283 0.0675
Schistosoma mansoni lozenge 0.0057 0.0251 0.0222
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0262 0.1212
Plasmodium falciparum SUMO-activating enzyme subunit 1 0.005 0.0202 0.0902
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0147 0.0833 0.2128
Echinococcus granulosus metabotropic glutamate receptor 2 0.0023 0.0029 0.002
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0025 0.0043 0.0079
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0063 0.0287 0.0287
Loa Loa (eye worm) hypothetical protein 0.0609 0.3817 0.3814
Echinococcus multilocularis gamma secretase subunit aph 1 0.0118 0.0641 0.0632
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0166 0.0956 0.2583
Brugia malayi Tachykinin-like peptides receptor 99D 0.0036 0.0111 0.0111
Schistosoma mansoni alpha-1 adrenergic receptor 0.0036 0.0111 0.0082
Onchocerca volvulus Protein ultraspiracle homolog 0.0096 0.0503 0.049
Brugia malayi hypothetical protein 0.0045 0.0174 0.0174
Loa Loa (eye worm) intermediate filament protein 0.0042 0.0149 0.0144
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0024
Echinococcus granulosus tachykinin peptides receptor 99D 0.0036 0.0111 0.0101
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0065 0.0303 0.0293
Toxoplasma gondii thioredoxin reductase 0.0073 0.0352 0.1677
Brugia malayi Nuclear hormone receptor-like 1 0.0051 0.0209 0.0209
Brugia malayi gamma-secretase subunit aph-1 0.0118 0.0641 0.0641
Onchocerca volvulus 0.0036 0.0111 0.0097
Echinococcus granulosus glutamate receptor 2 0.0153 0.0872 0.0863
Onchocerca volvulus 0.0232 0.1381 0.1369
Echinococcus multilocularis sex peptide receptor 0.0036 0.0111 0.0101
Leishmania major DNA polymerase eta, putative 0.0037 0.012 0.0245
Schistosoma mansoni neuropeptide F-like receptor 0.0036 0.0111 0.0082
Loa Loa (eye worm) hypothetical protein 0.0051 0.0209 0.0205
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Echinococcus granulosus L aminoadipate semialdehyde 0.0081 0.0403 0.0393
Trypanosoma cruzi Aph-1 protein, putative 0.0046 0.0177 0.0389
Loa Loa (eye worm) animal heme peroxidase 0.0027 0.0055 0.005
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Schistosoma mansoni zinc finger protein 0.0028 0.006 0.0031
Trichomonas vaginalis ap endonuclease, putative 0.0029 0.0068 0.0104
Brugia malayi steroid hormone receptor 0.0096 0.0503 0.0503
Echinococcus granulosus sodium and chloride dependent glycine 0.0266 0.1598 0.159
Echinococcus granulosus histone deacetylase 0.0092 0.0474 0.0465
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Trypanosoma cruzi DNA polymerase eta, putative 0.0037 0.012 0.0239
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0036 0.0111 0.0111
Echinococcus granulosus serotonin transporter 0.1565 1 1
Brugia malayi hypothetical protein 0.0036 0.0111 0.0111
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0036 0.0111 0.0111
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0044 0.0167 0.0362
Onchocerca volvulus Serine\/threonine kinase homolog 0.0092 0.0474 0.046
Echinococcus multilocularis lamin 0.0042 0.0149 0.0139
Loa Loa (eye worm) hypothetical protein 0.0038 0.0127 0.0122
Echinococcus granulosus glutamate receptor 2 0.0199 0.1163 0.1155
Echinococcus multilocularis sodium and chloride dependent glycine 0.0266 0.1598 0.159
Trypanosoma brucei Aph-1 protein, putative 0.0046 0.0177 0.0395
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0096 0.0503 0.0499
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0266 0.1598 0.1573
Toxoplasma gondii histone deacetylase HDAC3 0.0322 0.1963 1
Brugia malayi Carboxylesterase family protein 0.007 0.0332 0.0332
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0065 0.0303 0.0293
Echinococcus multilocularis phosphatidylinositol 5 phosphate 4 kinase type 2 0.0158 0.0902 0.0893
Echinococcus multilocularis musashi 0.0042 0.0149 0.0139
Onchocerca volvulus 0.0042 0.0149 0.0135
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0355 0.0326
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0262 0.0678
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0045 0.0174 0.0164
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0262 0.0233
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0185 0.1076 0.2912
Loa Loa (eye worm) TAR-binding protein 0.0073 0.0355 0.035
Brugia malayi Nuclear hormone receptor E75 0.0045 0.0174 0.0174
Echinococcus granulosus carboxylesterase 5A 0.007 0.0332 0.0323
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0031
Trypanosoma brucei histone deacetylase, putative 0.0092 0.0474 0.118
Brugia malayi Histone deacetylase family protein 0.0092 0.0474 0.0474
Loa Loa (eye worm) RNA binding protein 0.0073 0.0355 0.035
Loa Loa (eye worm) hypothetical protein 0.0089 0.0453 0.0449
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0036 0.011 0.024
Mycobacterium tuberculosis Conserved hypothetical protein 0.0107 0.0573 0.1532
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0147 0.0833 0.2123
Schistosoma mansoni glutamate receptor kainate 0.021 0.1238 0.1212
Loa Loa (eye worm) RGC/RGC protein kinase 0.0025 0.0038 0.0034
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0185 0.1076 0.2912
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0064 0.0291 0.1365
Toxoplasma gondii eukaryotic initiation factor-4E, putative 0.0036 0.011 0.0429
Entamoeba histolytica hypothetical protein 0.0023 0.0029 0.0012
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0233 0.1387 0.1379
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0157 0.0342
Onchocerca volvulus 0.0036 0.0111 0.0097
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0079 0.0391 0.1034
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0251 0.1506 0.1498
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0025 0.0043 0.0079
Loa Loa (eye worm) hypothetical protein 0.0045 0.0174 0.0169
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.005
Trypanosoma cruzi trypanothione reductase, putative 0.0073 0.0352 0.0851
Onchocerca volvulus Peroxidase homolog 0.0027 0.0055 0.0041
Brugia malayi putative neuropeptide receptor 0.0036 0.0111 0.0111
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0096 0.0503 0.0494
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0036 0.011 0.0213
Entamoeba histolytica hypothetical protein 0.0039 0.013 0.0534
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0076 0.0253
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0266 0.1598 0.8114
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0087 0.0441 0.0427
Schistosoma mansoni hypothetical protein 0.0261 0.157 0.1545
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.0605 0.2986
Trypanosoma brucei DNA polymerase eta, putative 0.0061 0.0275 0.0655
Brugia malayi histone deacetylase 3 (HD3) 0.0322 0.1963 0.1963
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0266 0.1598 0.1594
Toxoplasma gondii aminopeptidase N protein 0.0024 0.0035 0.0043
Echinococcus granulosus neuropeptide FF receptor 2 0.0036 0.0111 0.0101
Loa Loa (eye worm) histone deacetylase 7A 0.0092 0.0474 0.047
Brugia malayi putative neuropeptide receptor NPR1 0.0036 0.0111 0.0111
Plasmodium falciparum M1-family alanyl aminopeptidase 0.0024 0.0035 0.0043
Leishmania major histone deacetylase, putative 0.0092 0.0474 0.118
Loa Loa (eye worm) hypothetical protein 0.0096 0.0503 0.0499
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0025 0.0043 0.0085
Leishmania major eukaryotic translation initiation factor eIF-4E, putative 0.0036 0.011 0.0219
Schistosoma mansoni peroxidasin 0.0027 0.0055 0.0026
Loa Loa (eye worm) nuclear hormone receptor 0.0045 0.0174 0.0169
Echinococcus granulosus 7TM GPCR rhodopsin 0.0036 0.0111 0.0101
Trypanosoma brucei Aminopeptidase M1, putative 0.0068 0.0322 0.0778
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0068 0.0322 0.0772
Echinococcus multilocularis neuropeptide Y receptor 0.0036 0.0111 0.0101
Echinococcus multilocularis polycomb protein SCMH1 0.0087 0.0441 0.0432
Entamoeba histolytica recQ family helicase, putative 0.0038 0.0126 0.0511
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0076 0.013
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0199 0.1163 0.1155
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0036 0.0111 0.0082
Schistosoma mansoni hypothetical protein 0.0036 0.0111 0.0082
Trichomonas vaginalis mercuric reductase, putative 0.0025 0.0043 0.0026
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0068 0.0322 0.0312
Onchocerca volvulus 0.0027 0.0055 0.0041
Loa Loa (eye worm) hypothetical protein 0.0054 0.0227 0.0222
Echinococcus granulosus tm gpcr rhodopsin 0.0036 0.0111 0.0101
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0048 0.0192 0.0853
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0111 0.0082
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0024
Schistosoma mansoni biogenic amine receptor 0.0036 0.0111 0.0082
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0036 0.0111 0.0106
Loa Loa (eye worm) blistered cuticle protein 3 0.0027 0.0055 0.005
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0045 0.0171 0.0162
Entamoeba histolytica hypothetical protein 0.0039 0.013 0.0534
Brugia malayi nuclear receptor NHR-67 0.0045 0.0174 0.0174
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0034 0.01 0.009
Toxoplasma gondii endonuclease IV APN 0.0079 0.0391 0.1882
Trypanosoma cruzi histone deacetylase, putative 0.0092 0.0474 0.1174
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Echinococcus multilocularis rhodopsin orphan GPCR 0.0036 0.0111 0.0101
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0024 0.0035 0.0026
Mycobacterium tuberculosis Conserved hypothetical protein 0.0107 0.0573 0.1532
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0102 0.0538 0.135
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0096 0.0503 0.0475
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0036 0.0111 0.0082
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.005
Echinococcus granulosus histone deacetylase 7 0.0092 0.0474 0.0465
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0038 0.0126 0.0261
Brugia malayi hypothetical protein 0.0062 0.0282 0.0282
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0102 0.0538 0.1344
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0095 0.0492 0.0464
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0063 0.0287 0.0258
Echinococcus granulosus lamin 0.0042 0.0149 0.0139
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0102 0.0538 0.0534
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0024 0.0035 0.0016
Onchocerca volvulus 0.0096 0.0503 0.049
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0312 0.1895 0.4928
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0096 0.0503 0.0503
Brugia malayi AKH receptor 0.0036 0.0111 0.0111
Treponema pallidum licC protein (licC) 0.0107 0.0573 0.0548
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0025 0.0043 0.0037
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0036 0.0111 0.0101
Loa Loa (eye worm) hypothetical protein 0.0045 0.0174 0.0169
Loa Loa (eye worm) hypothetical protein 0.0322 0.1963 0.1959
Onchocerca volvulus 0.0036 0.0111 0.0097
Schistosoma mansoni nuclear hormone receptor 0.0045 0.0174 0.0145
Brugia malayi histone deacetylase 1 (HD1) 0.0322 0.1963 0.1963
Loa Loa (eye worm) hypothetical protein 0.0311 0.1892 0.1888
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0266 0.1598 0.1573
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0266 0.1598 0.1573
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0185 0.1076 0.2912
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0036 0.0111 0.0106
Loa Loa (eye worm) glutamate receptor 2 0.0122 0.0667 0.0663
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Mycobacterium ulcerans hypothetical protein 0.0107 0.0573 0.1532
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0174 0.0446
Schistosoma mansoni glutamate receptor NMDA 0.0122 0.0667 0.064
Echinococcus multilocularis histone deacetylase 8 0.0092 0.0474 0.0465
Schistosoma mansoni retinoic acid receptor RXR 0.0249 0.1487 0.1462
Onchocerca volvulus 0.0266 0.1598 0.1586
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0045 0.0171 0.0162
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0355 0.0326
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0414 0.2559 0.2552
Trypanosoma brucei C-8 sterol isomerase, putative 0.0609 0.3817 1
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0266 0.1598 0.159
Brugia malayi neuropeptide F receptor 0.0036 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0076 0.0253
Schistosoma mansoni glutamate receptor AMPA 0.0122 0.0667 0.064
Schistosoma mansoni opsin-like receptor 0.0036 0.0111 0.0082
Echinococcus granulosus g protein coupled receptor 0.0036 0.0111 0.0101
Schistosoma mansoni sodium/chloride dependent transporter 0.1565 1 1
Echinococcus granulosus transcription factor Dp 1 0.0059 0.0261 0.0252
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0096 0.0503 0.0499
Loa Loa (eye worm) hypothetical protein 0.005 0.0202 0.0197
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0025 0.0043 0.0034
Schistosoma mansoni neuropeptide receptor 0.0036 0.0111 0.0082
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0036 0.0111 0.0082
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0045 0.0174 0.0145
Giardia lamblia Kinase, PLK 0.0092 0.0474 0.2242
Echinococcus granulosus receptor type guanylyl cyclase 0.0025 0.0038 0.0029
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0112 0.0605 0.058
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0024 0.0035 0.0022
Onchocerca volvulus 0.0045 0.0174 0.016
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0233 0.1387 0.1379
Echinococcus multilocularis 6 phosphofructokinase 0.0112 0.0605 0.0596
Brugia malayi hypothetical protein 0.023 0.1366 0.1366
Echinococcus multilocularis SUMO activating enzyme subunit 2 0.0033 0.0092 0.0082
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0027 0.0034
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0029 0.0068 0.0107
Brugia malayi PHD-finger family protein 0.0049 0.0197 0.0197
Echinococcus multilocularis Protein lozenge 0.0057 0.0251 0.0241
Echinococcus granulosus nuclear receptor nhr 48 0.0045 0.0174 0.0164
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0068 0.0322 0.0778
Loa Loa (eye worm) hypothetical protein 0.0457 0.2835 0.2831
Plasmodium falciparum SUMO-activating enzyme subunit 2 0.0033 0.0092 0.0334
Onchocerca volvulus Peroxidase homolog 0.0027 0.0055 0.0041
Echinococcus granulosus biogenic amine 5HT receptor 0.0036 0.0111 0.0101
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0127 0.0265
Echinococcus granulosus tm gpcr rhodopsin 0.0036 0.0111 0.0101
Loa Loa (eye worm) hypothetical protein 0.0122 0.0667 0.0663
Loa Loa (eye worm) glutamate receptor 1 0.0175 0.1014 0.101
Echinococcus granulosus rhodopsin orphan GPCR 0.0036 0.0111 0.0101
Schistosoma mansoni hypothetical protein 0.0035 0.0105 0.0076
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0036 0.0111 0.0101
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0063 0.0287 0.0747
Mycobacterium ulcerans endonuclease IV 0.0079 0.0391 0.1034
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0112 0.0606 0.0597
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0036 0.0111 0.0082
Trypanosoma cruzi polo-like protein kinase, putative 0.0092 0.0474 0.1173
Schistosoma mansoni tyrosine kinase 0.0025 0.0038 0.0009
Echinococcus multilocularis G protein coupled receptor 139 0.0036 0.0111 0.0101
Brugia malayi nuclear receptor NHR-88 0.0096 0.0503 0.0503
Brugia malayi Peptidase family M1 containing protein 0.0068 0.0322 0.0322
Brugia malayi Dopamine receptor protein 1 0.0036 0.0111 0.0111
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0112 0.0605 0.1525
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Brugia malayi serine/threonine-protein kinase plk-2 0.0092 0.0474 0.0474
Mycobacterium tuberculosis Conserved hypothetical protein 0.0164 0.0941 0.2542
Brugia malayi Animal haem peroxidase family protein 0.0027 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0208 0.1226 0.1222
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0063 0.0287 0.0747
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0025 0.0043 0.0043
Loa Loa (eye worm) TATA binding protein associated factor 0.0024 0.0035 0.0031
Echinococcus granulosus g protein coupled receptor 0.0036 0.0111 0.0101
Echinococcus granulosus thioredoxin glutathione reductase 0.0073 0.0352 0.0342
Loa Loa (eye worm) hypothetical protein 0.0266 0.1598 0.1594
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0096 0.0503 0.0503
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0079 0.0138
Toxoplasma gondii NADPH-glutathione reductase 0.0025 0.0043 0.0085
Leishmania major ATP-dependent phosphofructokinase 0.0112 0.0605 0.1525
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0025 0.0043 0.0085
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0036 0.011 0.0213
Plasmodium vivax thioredoxin reductase, putative 0.0073 0.0352 0.1677
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0036 0.0111 0.0082
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0043 0.0157 0.0336
Plasmodium falciparum histone deacetylase 1 0.0322 0.1963 1
Schistosoma mansoni aminopeptidase A (M01 family) 0.0024 0.0035 0.0006
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0068 0.0322 0.0312
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0036 0.0111 0.0082
Schistosoma mansoni tyrosine kinase 0.0025 0.0038 0.0009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0096 0.0503 0.0499
Schistosoma mansoni hypothetical protein 0.0047 0.0183 0.0154
Loa Loa (eye worm) hypothetical protein 0.0037 0.0117 0.0112
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0096 0.0503 0.0494
Brugia malayi phosphofructokinase 0.0112 0.0605 0.0605
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0119 0.0647 0.062
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0029 0.0068 0.0058
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0049 0.0199 0.089
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0474 0.141
Loa Loa (eye worm) hypothetical protein 0.1565 1 1
Loa Loa (eye worm) peptidase family M1 containing protein 0.0188 0.1095 0.109
Echinococcus granulosus glutamate receptor 4 0.0054 0.0227 0.0217
Loa Loa (eye worm) hypothetical protein 0.0036 0.0111 0.0106
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0076 0.0253
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0035 0.0105 0.0076
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0045 0.0174 0.0169
Loa Loa (eye worm) carboxylesterase 0.007 0.0332 0.0327
Loa Loa (eye worm) histone deacetylase 1 0.0322 0.1963 0.1959
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0076 0.013
Loa Loa (eye worm) hypothetical protein 0.0054 0.0227 0.0222
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0023 0.0029 0.0024
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0096 0.0503 0.0503
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0095 0.0492 0.0483
Plasmodium falciparum amino acid transporter, putative 0.0266 0.1598 0.8114
Loa Loa (eye worm) hypothetical protein 0.0457 0.2835 0.2831
Loa Loa (eye worm) hypothetical protein 0.0051 0.0209 0.0205
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0092 0.0474 0.0469
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0283 0.0675
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.0209 0.0209
Echinococcus multilocularis SAM and MBT domain containing protein 0.0087 0.0441 0.0432
Trypanosoma cruzi DNA polymerase kappa, putative 0.0062 0.0283 0.0669

Activities

Activity type Activity value Assay description Source Reference
-Log MIC (functional) = 0.89 Antimicrobial activity against Staphylococcus aureus after 24 hrs by two-fold serial dilution method ChEMBL. 17869511
-Log MIC (functional) = 0.89 Antimicrobial activity against Escherichia coli after 24 hrs by two-fold serial dilution method ChEMBL. 17869511
-Log MIC (functional) = 1 Antifungal activity against Aspergillus niger after 7 days by two-fold serial dilution method ChEMBL. 17869511
-Log MIC (functional) = 1.05 Antimicrobial activity against Bacillus subtilis after 24 hrs by two-fold serial dilution method ChEMBL. 17869511
-Log MIC (functional) = 1.11 Antifungal activity against Candida albicans after 2 days by two-fold serial dilution method ChEMBL. 17869511
LogP = 1.84 Partition coefficient, log P of the compound ChEMBL. 17869511
MIC (functional) = 0.89 Antimicrobial activity against Escherichia coli after 24 hrs by two-fold serial dilution method ChEMBL. 17869511
MIC (functional) = 1.11 Antifungal activity against Candida albicans after 2 days by two-fold serial dilution method ChEMBL. 17869511

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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