Detailed information for compound 47372

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 309.321 | Formula: C13H19N5O4
  • H donors: 4 H acceptors: 6 LogP: -0.44 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@@H]1O[C@@H]([C@H]([C@@H]1O)O)n1cnc2c1ncnc2NC(C)C
  • InChi: 1S/C13H19N5O4/c1-6(2)17-11-8-12(15-4-14-11)18(5-16-8)13-10(21)9(20)7(3-19)22-13/h4-7,9-10,13,19-21H,3H2,1-2H3,(H,14,15,17)/t7-,9+,10?,13-/m1/s1
  • InChiKey: LILZBBGKOTULGC-ZIUXOXTBSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis histone lysine N methyltransferase NSD3 0.0035 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0035 0.0022 0.0022
Echinococcus multilocularis fmrfamide receptor 0.0239 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0037 0.0024 0.0024
Echinococcus multilocularis muscleblind protein 0.0608 0.0723 0.0723
Loa Loa (eye worm) pigment dispersing factor receptor c 0.1497 0.1808 0.1808
Plasmodium vivax histone acetyltransferase GCN5, putative 0.009 0.0089 0.0187
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0053 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.1392 0.168 0.168
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0024 0.0024
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0291 0.0335 0.0335
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0009 0.0027
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.1392 0.168 0.168
Onchocerca volvulus 0.0021 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0053 0.0044 0.0044
Mycobacterium tuberculosis Probable dehydrogenase 0.0509 0.0601 0.1268
Leishmania major mitochondrial DNA polymerase beta 0.0307 0.0355 0.0742
Schistosoma mansoni sodium/chloride dependent transporter 0.1392 0.168 0.168
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0075 0.0071 0.9614
Brugia malayi Nuclear hormone receptor E75 0.0045 0.0034 0.0034
Echinococcus multilocularis Niemann Pick C1 protein 0.0105 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0014
Echinococcus multilocularis thioredoxin glutathione reductase 0.0224 0.0253 0.0253
Schistosoma mansoni glutamate synthase 0.0021 0.0004 0.0004
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0035 0.0022 0.0022
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0003 0.0003
Schistosoma mansoni RAR-like nuclear receptor 0.0095 0.0095 0.0095
Mycobacterium ulcerans DNA polymerase IV 0.0103 0.0106 0.0217
Echinococcus granulosus glycine receptor subunit alpha 1 0.0053 0.0044 0.0044
Mycobacterium ulcerans ferredoxin reductase 0.0021 0.0004 0.0003
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0095 0.0095 0.0095
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0082 0.008 0.0162
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0077 0.0074 0.0154
Echinococcus multilocularis protein kinase c eta type 0.0035 0.0022 0.0022
Schistosoma mansoni hypothetical protein 0.0043 0.0032 0.0032
Echinococcus granulosus neuropeptide receptor 0.0395 0.0462 0.0462
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0045 0.0034 0.0034
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0128 0.0136 0.0136
Leishmania major hypothetical protein, conserved 0.0021 0.0004 0.0009
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Trypanosoma brucei unspecified product 0.0052 0.0043 0.0089
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0035 0.0022 0.0022
Echinococcus multilocularis g protein coupled receptor 0.0239 0.0272 0.0272
Loa Loa (eye worm) apoptosis regulator protein 0.012 0.0126 0.0126
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0021 0.0004 0.0003
Brugia malayi hypothetical protein 0.0239 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0104 0.0106 0.0106
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0043 0.0032 0.0062
Echinococcus multilocularis pyruvate kinase 0.0069 0.0064 0.0064
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0003 0.0003
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0003 0.0003
Entamoeba histolytica pyruvate kinase, putative 0.0048 0.0039 0.3395
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0077 0.0074 0.0154
Echinococcus multilocularis Transglutaminase 0.0111 0.0115 0.0115
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0095 0.0095 0.0095
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0095 0.0095 0.0095
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0029 0.0014 0.0014
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0077 0.0074 0.0154
Schistosoma mansoni hypothetical protein 0.0147 0.0159 0.0159
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0021 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0045 0.0034 0.0034
Brugia malayi Nuclear hormone receptor-like 1 0.0095 0.0095 0.0095
Echinococcus multilocularis tachykinin peptides receptor 99D 0.2277 0.2762 0.2762
Echinococcus granulosus glutamate receptor 2 0.0042 0.003 0.003
Schistosoma mansoni retinoid-x-receptor (RXR) 0.005 0.0041 0.0041
Echinococcus granulosus Protein kinase C brain isozyme 0.0035 0.0022 0.0022
Schistosoma mansoni atypical protein kinase C 0.0035 0.0022 0.0022
Echinococcus multilocularis NMDA receptor 0.0043 0.0032 0.0032
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0022 0.0006 0.0011
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.005 0.0041 0.0041
Brugia malayi ORL1-like opioid receptor 0.0239 0.0272 0.0272
Schistosoma mansoni growth hormone secretagogue receptor 0.0239 0.0272 0.0272
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0024 0.0009 0.0009
Loa Loa (eye worm) mbt repeat family protein 0.0049 0.0039 0.0039
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0025 0.001 0.0015
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0045 0.0034 0.0034
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0239 0.0272 0.0272
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0035 0.0022 0.0022
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0095 0.0095 0.0095
Echinococcus multilocularis sterol regulatory element binding protein 0.0045 0.0034 0.0034
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0053 0.0044 0.0044
Loa Loa (eye worm) MBCTL1 0.0055 0.0047 0.0047
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0239 0.0272 0.0272
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0021 0.0004 0.0003
Echinococcus granulosus GPCR family 2 0.037 0.0432 0.0432
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0239 0.0272 0.0272
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0021 0.0004 0.0004
Echinococcus multilocularis sodium and chloride dependent glycine 0.1392 0.168 0.168
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.0044 0.0044
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0105 0.0107 0.0107
Loa Loa (eye worm) ACC-1 protein 0.0053 0.0044 0.0044
Mycobacterium ulcerans transglutaminase family protein 0.0111 0.0115 0.0236
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0003 0.0003
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0075 0.0071 0.0149
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0058 0.0058
Schistosoma mansoni neurotransmitter gated ion channel 0.0029 0.0014 0.0014
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0239 0.0272 0.0272
Leishmania major DNA polymerase eta, putative 0.0128 0.0136 0.0284
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.1392 0.168 0.168
Echinococcus multilocularis folate receptor beta 0.0821 0.0983 0.0983
Echinococcus multilocularis metabotropic glutamate receptor 5 0.002 0.0004 0.0004
Brugia malayi hypothetical protein 0.0019 0.0003 0.0003
Schistosoma mansoni myosin xvIII 0.0239 0.0272 0.0272
Trypanosoma cruzi NADH dehydrogenase, putative 0.0021 0.0004 0.0009
Schistosoma mansoni hypothetical protein 0.0239 0.0272 0.0272
Echinococcus granulosus tyrosine kinase 0.0026 0.0011 0.0011
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.1392 0.168 0.168
Echinococcus granulosus 7TM GPCR rhodopsin 0.0239 0.0272 0.0272
Trypanosoma brucei unspecified product 0.0052 0.0043 0.0089
Brugia malayi jmjC domain containing protein 0.0036 0.0024 0.0024
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0003 0.0003
Schistosoma mansoni glutamate receptor kainate 0.0065 0.0058 0.0058
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0239 0.0272 0.0269
Entamoeba histolytica hypothetical protein 0.002 0.0004 0.0087
Schistosoma mansoni hypothetical protein 0.0534 0.0632 0.0632
Echinococcus granulosus neuropeptides capa receptor 0.0239 0.0272 0.0272
Schistosoma mansoni nAChR subunit 0.0053 0.0044 0.0044
Brugia malayi Serotonin receptor 0.0239 0.0272 0.0272
Trypanosoma brucei pyruvate kinase 1 0.0069 0.0064 0.0134
Onchocerca volvulus 0.0128 0.0136 0.0133
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0095 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Loa Loa (eye worm) TAR-binding protein 0.0064 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Onchocerca volvulus 0.0029 0.0014 0.0011
Schistosoma mansoni hypothetical protein 0.0043 0.0032 0.0032
Echinococcus multilocularis rhodopsin orphan GPCR 0.0239 0.0272 0.0272
Brugia malayi Glutamate receptor 2 precursor 0.0065 0.0058 0.0058
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0095 0.0095 0.0095
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0035 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0053 0.0044 0.0044
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0077 0.0074 0.0074
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.005 0.0041 0.0041
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.1499 0.1811 0.1811
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0021 0.0004 0.0006
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0077 0.0074 0.0154
Trypanosoma brucei unspecified product 0.0096 0.0097 0.0203
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0239 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0053 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0053 0.0044 0.0044
Toxoplasma gondii thioredoxin reductase 0.0223 0.0252 0.0528
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.009 0.0089 0.0386
Loa Loa (eye worm) hypothetical protein 0.0053 0.0044 0.0044
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.003 0.0016 0.0034
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0057 0.0049 0.0049
Echinococcus multilocularis Niemann Pick C1 protein 0.015 0.0162 0.0162
Onchocerca volvulus 0.0128 0.0136 0.0133
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0022 0.004
Loa Loa (eye worm) hypothetical protein 0.037 0.0432 0.0432
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.1392 0.168 0.168
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0085 0.0083 0.0083
Brugia malayi mbt repeat family protein 0.0049 0.0039 0.0039
Entamoeba histolytica acyl-coA synthetase, putative 0.0049 0.0039 0.3478
Brugia malayi hypothetical protein 0.0024 0.0009 0.0009
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0239 0.0272 0.0272
Schistosoma mansoni ap endonuclease 0.0075 0.0071 0.0071
Brugia malayi larval opioid receptor 0.0239 0.0272 0.0272
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0095 0.0095 0.0095
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.1392 0.168 0.168
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0566 0.0671 0.1415
Plasmodium falciparum glutathione reductase 0.0223 0.0252 0.0528
Onchocerca volvulus 0.0024 0.0009 0.0006
Brugia malayi CXXC zinc finger family protein 0.0031 0.0017 0.0017
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.009 0.0089 0.0187
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0077 0.0074 0.0155
Onchocerca volvulus 0.0141 0.0151 0.0148
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0239 0.0272 0.0272
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0106 0.0109 0.0109
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.0058 0.0058
Brugia malayi hypothetical protein 0.1847 0.2236 0.2236
Brugia malayi RNA, U transporter 1 0.0048 0.0038 0.0038
Treponema pallidum exodeoxyribonuclease (exoA) 0.0075 0.0071 0.0067
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0009
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0077 0.0074 0.0155
Schistosoma mansoni neuropeptide F-like receptor 0.0239 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0053 0.0044 0.0044
Brugia malayi Calcitonin receptor-like protein seb-1 0.1497 0.1808 0.1808
Loa Loa (eye worm) hypothetical protein 0.0053 0.0044 0.0044
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0053 0.0044 0.0044
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.0061 0.0061
Echinococcus granulosus thyroid hormone receptor alpha 0.0045 0.0034 0.0034
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0013 0.0026
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0078 0.0075 0.0152
Brugia malayi exodeoxyribonuclease III family protein 0.0075 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0095 0.0095 0.0095
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0045 0.0034 0.0034
Echinococcus multilocularis neuropeptide receptor 0.0395 0.0462 0.0462
Schistosoma mansoni cellular tumor antigen P53 0.0053 0.0044 0.0044
Plasmodium vivax DNA repair protein REV1, putative 0.0023 0.0008 0.0016
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.0032 0.0067
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0045 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0053 0.0044 0.0044
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.1392 0.168 0.168
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0003 0.0003
Plasmodium vivax pyruvate kinase 2, putative 0.0036 0.0023 0.0048
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0014
Brugia malayi glutamate synthase 0.0021 0.0004 0.0004
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0223 0.0252 0.0528
Schistosoma mansoni hypothetical protein 0.012 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Schistosoma mansoni cpg binding protein 0.0032 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0035 0.0022 0.0022
Loa Loa (eye worm) RasGEF domain-containing protein 0.0035 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0021 0.0004 0.0006
Mycobacterium ulcerans monoxygenase 0.0021 0.0004 0.0003
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0206 0.0232 0.0232
Entamoeba histolytica diacylglycerol kinase, putative 0.0035 0.0022 0.1844
Echinococcus multilocularis expressed protein 0.0379 0.0443 0.0443
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0077 0.0074 0.0155
Brugia malayi Variant SH3 domain containing protein 0.0035 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0035 0.0022 0.0022
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0021 0.0004 0.0009
Echinococcus multilocularis sex peptide receptor 0.0239 0.0272 0.0272
Schistosoma mansoni unc-13 (munc13) 0.0035 0.0022 0.0022
Toxoplasma gondii aldehyde dehydrogenase 0.0067 0.0061 0.0129
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0024 0.0009 0.0009
Echinococcus multilocularis muscleblind protein 1 0.0608 0.0723 0.0723
Giardia lamblia Histone acetyltransferase GCN5 0.0083 0.008 0.6879
Echinococcus granulosus G protein coupled receptor 139 0.0239 0.0272 0.0272
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0057 0.0049 0.0049
Echinococcus granulosus snurportin 1 0.018 0.02 0.02
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.1697 0.2053 0.2053
Onchocerca volvulus Folate transporter 1 homolog 0.005 0.004 0.0037
Schistosoma mansoni hypothetical protein 0.012 0.0126 0.0126
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0045 0.0034 0.0034
Echinococcus granulosus pyruvate kinase 0.0036 0.0023 0.0023
Schistosoma mansoni zinc finger protein 0.0045 0.0034 0.0034
Loa Loa (eye worm) steroid hormone receptor 0.0095 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0105 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0053 0.0044 0.0044
Loa Loa (eye worm) glutamate receptor 0.002 0.0004 0.0004
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0075 0.0071 0.0148
Brugia malayi orphan nuclear receptor NR2E1 0.0045 0.0034 0.0034
Schistosoma mansoni hypothetical protein 0.037 0.0432 0.0432
Brugia malayi Serotonin receptor 0.0239 0.0272 0.0272
Echinococcus multilocularis neuropeptide FF receptor 2 0.0239 0.0272 0.0272
Trypanosoma brucei DNA polymerase kappa, putative 0.0103 0.0106 0.0221
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0025 0.001 0.0805
Trypanosoma brucei hypothetical protein, conserved 0.0021 0.0004 0.0009
Loa Loa (eye worm) hypothetical protein 0.0765 0.0914 0.0914
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0021 0.0004 0.0006
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0239 0.0272 0.0272
Trichomonas vaginalis peptide N-glycanase, putative 0.0111 0.0115 0.0499
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0021 0.0004 0.0004
Echinococcus multilocularis neuropeptides capa receptor 0.0239 0.0272 0.0272
Schistosoma mansoni retinoic acid receptor RXR 0.0095 0.0095 0.0095
Mycobacterium ulcerans hypothetical protein 0.0049 0.0039 0.0077
Echinococcus granulosus tachykinin peptides receptor 99D 0.2277 0.2762 0.2762
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0105 0.0107 0.0107
Loa Loa (eye worm) serotonin transporter b 0.8201 1 1
Echinococcus granulosus tm gpcr rhodopsin 0.075 0.0896 0.0896
Loa Loa (eye worm) hypothetical protein 0.0035 0.0022 0.0022
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0003 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0082 0.008 0.0167
Loa Loa (eye worm) translation initiation factor 4E 0.0035 0.0022 0.0022
Onchocerca volvulus 0.0239 0.0272 0.0269
Leishmania major DNA polymerase eta, putative 0.0076 0.0073 0.0151
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0239 0.0272 0.0272
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0076 0.0073 0.0152
Schistosoma mansoni cpg binding protein 0.0031 0.0017 0.0017
Onchocerca volvulus 0.005 0.004 0.0037
Echinococcus granulosus neuropeptide receptor 0.0239 0.0272 0.0272
Echinococcus multilocularis lysine specific demethylase 5A 0.0034 0.0021 0.0021
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0076 0.0073 0.0073
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0039 0.0082
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0095 0.0095 0.0095
Mycobacterium leprae Conserved hypothetical protein 0.0111 0.0115 0.0237
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0103 0.0106 0.0459
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0075 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0055 0.0047 0.0047
Echinococcus granulosus bloom syndrome protein 0.0024 0.0009 0.0009
Echinococcus granulosus histone acetyltransferase KAT2B 0.009 0.0089 0.0089
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0021 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Mycobacterium tuberculosis Conserved hypothetical protein 0.0111 0.0115 0.0237
Trypanosoma cruzi trypanothione reductase, putative 0.0223 0.0252 0.0527
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0022 0.004
Echinococcus granulosus nmda type glutamate receptor 0.002 0.0004 0.0004
Brugia malayi Pyruvate kinase, M2 isozyme 0.0069 0.0064 0.0064
Loa Loa (eye worm) RNA binding protein 0.0064 0.0058 0.0058
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0078 0.0075 0.042
Onchocerca volvulus 0.0239 0.0272 0.0269
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0021 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0128 0.0136 0.0136
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0239 0.0272 0.0272
Mycobacterium ulcerans pyruvate kinase 0.0069 0.0064 0.0129
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0013 0.0027
Brugia malayi PXA domain containing protein 0.0019 0.0003 0.0003
Schistosoma mansoni rac gtpase activating protein 0.0035 0.0022 0.0022
Brugia malayi Pleckstrin Homology Domain 0.0035 0.0022 0.0022
Brugia malayi hypothetical protein 0.0251 0.0287 0.0287
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0061 0.0123
Toxoplasma gondii hypothetical protein 0.1392 0.168 0.3518
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0145 0.0157 0.0328
Echinococcus granulosus Major facilitator superfamily general substrate transporter 0.0148 0.016 0.016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0239 0.0272 0.0272
Echinococcus granulosus SAM and MBT domain containing protein 0.0049 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0009
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.1392 0.168 0.168
Toxoplasma gondii histone lysine methyltransferase SET1 0.0067 0.0061 0.0128
Leishmania major trypanothione reductase 0.0223 0.0252 0.0527
Mycobacterium ulcerans DNA polymerase IV 0.0103 0.0106 0.0217
Echinococcus multilocularis neuropeptide Y receptor 0.0239 0.0272 0.0272
Leishmania major eukaryotic translation initiation factor-like 0.0035 0.0022 0.0045
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0021 0.0004 0.0122
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0057 0.0049 0.0049
Leishmania major DNA polymerase kappa, putative 0.0023 0.0008 0.0016
Schistosoma mansoni sodium-dependent amino acid transporter 0.1392 0.168 0.168
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0039 0.0039
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0003 0.0003
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0128 0.0136 0.0136
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0075 0.0071 0.0071
Brugia malayi TAR-binding protein 0.0064 0.0058 0.0058
Echinococcus multilocularis pyruvate kinase 0.0036 0.0023 0.0023
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0239 0.0272 0.0272
Trypanosoma cruzi DNA polymerase kappa, putative 0.0103 0.0106 0.022
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0021 0.0004 0.0003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0077 0.0074 0.0154
Onchocerca volvulus Pyruvate kinase homolog 0.0069 0.0064 0.0061
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0509 0.0601 0.1268
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0021 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0075 0.0071 0.6051
Echinococcus granulosus microtubule associated protein 2 0.0734 0.0876 0.0876
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0075 0.0071 0.0071
Trypanosoma cruzi DNA polymerase kappa, putative 0.0103 0.0106 0.022
Echinococcus granulosus neuropeptide s receptor 0.4769 0.5807 0.5807
Onchocerca volvulus 0.0029 0.0014 0.0011
Schistosoma mansoni nAChR subunit 0.0053 0.0044 0.0044
Echinococcus multilocularis pyruvate kinase 0.0055 0.0046 0.0046
Echinococcus granulosus glycine receptor subunit alpha 1 0.0053 0.0044 0.0044
Onchocerca volvulus Huntingtin homolog 0.0062 0.0055 0.0052
Mycobacterium leprae Conserved hypothetical protein 0.0111 0.0115 0.0237
Schistosoma mansoni neurotransmitter gated ion channel 0.0024 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0021 0.0004 0.0004
Brugia malayi Metabotropic glutamate receptor precursor. 0.002 0.0004 0.0004
Brugia malayi hypothetical protein 0.0024 0.0009 0.0009
Mycobacterium ulcerans putative transglutaminase-like protein 0.0111 0.0115 0.0236
Brugia malayi steroid hormone receptor 0.0095 0.0095 0.0095
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0239 0.0272 0.0272
Onchocerca volvulus 0.0105 0.0107 0.0105
Echinococcus granulosus dna polymerase eta 0.0128 0.0136 0.0136
Echinococcus granulosus Diacylglycerol kinase theta 0.0035 0.0022 0.0022
Schistosoma mansoni protein kinase C 0.0035 0.0022 0.0022
Trichomonas vaginalis bromodomain-containing protein, putative 0.009 0.0089 0.0386
Loa Loa (eye worm) hypothetical protein 0.0128 0.0136 0.0136
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0049 0.0039 0.0077
Brugia malayi glutathione reductase 0.0223 0.0252 0.0252
Echinococcus granulosus allatostatin A receptor 0.0239 0.0272 0.0272
Brugia malayi nuclear hormone receptor 0.0045 0.0034 0.0034
Brugia malayi hypothetical protein 0.0024 0.0009 0.0009
Trypanosoma brucei DNA polymerase kappa, putative 0.0103 0.0106 0.0221
Echinococcus granulosus alpha 1A adrenergic receptor 0.0239 0.0272 0.0272
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0239 0.0272 0.0272
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.1499 0.1811 0.1811
Trichomonas vaginalis glutamate synthase, putative 0.0021 0.0004 0.0006
Mycobacterium ulcerans NADH dehydrogenase 0.0021 0.0004 0.0003
Schistosoma mansoni inositol monophosphatase 0.0022 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0009
Echinococcus granulosus nAChR subunit 0.0053 0.0044 0.0044
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.012 0.0126 0.0126
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0019 0.0003 0.0003
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0043 0.0032 0.0032
Plasmodium falciparum pyruvate kinase 0.0069 0.0064 0.0134
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0067 0.0061 0.0124
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Brugia malayi folate-like transporter 3 0.005 0.004 0.004
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0021 0.0004 0.0122
Echinococcus multilocularis dro:myosuppressin receptor 0.0239 0.0272 0.0272
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0009 0.0009
Loa Loa (eye worm) programmed cell death 8 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0045 0.0034 0.0034
Onchocerca volvulus 0.005 0.004 0.0037
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0239 0.0272 0.0272
Toxoplasma gondii hypothetical protein 0.0202 0.0226 0.0473
Onchocerca volvulus 0.0031 0.0017 0.0014
Schistosoma mansoni patched 1 0.0045 0.0034 0.0034
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.0042 0.0042
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0019 0.0003 0.0003
Onchocerca volvulus 0.0024 0.0009 0.0006
Echinococcus granulosus Niemann Pick C1 protein 0.015 0.0162 0.0162
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0043 0.0032 0.0032
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.005 0.004 0.004
Echinococcus granulosus metabotropic glutamate receptor 2 0.002 0.0004 0.0004
Loa Loa (eye worm) pyruvate kinase 0.0069 0.0064 0.0064
Echinococcus multilocularis tar DNA binding protein 0.0064 0.0058 0.0058
Onchocerca volvulus 0.0045 0.0034 0.0031
Echinococcus multilocularis pyruvate kinase 0.0069 0.0064 0.0064
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0013 0.0026
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0078 0.0075 0.007
Loa Loa (eye worm) inositol-1 0.0022 0.0006 0.0006
Trypanosoma brucei DNA polymerase kappa, putative 0.0103 0.0106 0.0221
Echinococcus multilocularis eukaryotic translation initiation factor 4E 0.0035 0.0022 0.0022
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0045 0.0034 0.0031
Echinococcus multilocularis receptor type guanylyl cyclase 0.0046 0.0035 0.0035
Brugia malayi hypothetical protein 0.0045 0.0034 0.0034
Brugia malayi photoreceptor-specific nuclear receptor 0.0095 0.0095 0.0095
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0076 0.0073 0.0073
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0003 0.0003
Plasmodium falciparum thioredoxin reductase 0.0223 0.0252 0.0528
Loa Loa (eye worm) glutamate receptor 1 0.0065 0.0058 0.0058
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0021 0.0004 0.0009
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0239 0.0272 0.0272
Schistosoma mansoni nAChR subunit 0.0024 0.0009 0.0009
Plasmodium falciparum amino acid transporter, putative 0.1392 0.168 0.3518
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.002 0.0004 0.0004
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0306 0.0354 0.0354
Schistosoma mansoni neuropeptide receptor 0.0395 0.0462 0.0462
Echinococcus multilocularis dna polymerase eta 0.0128 0.0136 0.0136
Onchocerca volvulus 0.0239 0.0272 0.0269
Brugia malayi hypothetical protein 0.1392 0.168 0.168
Entamoeba histolytica disulphide oxidoreductase, putative 0.0021 0.0004 0.0122
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0045 0.0034 0.0034
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.005 0.0041 0.0041
Schistosoma mansoni neuropeptide receptor 0.0239 0.0272 0.0272
Echinococcus multilocularis inositol monophosphatase 1 0.0022 0.0006 0.0006
Echinococcus multilocularis glutamate receptor 2 0.0065 0.0058 0.0058
Echinococcus multilocularis geminin 0.0534 0.0632 0.0632
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0014
Brugia malayi translation initiation factor 4E 0.0035 0.0022 0.0022
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0128 0.0136 0.0136
Echinococcus granulosus metabotropic glutamate receptor 5 0.002 0.0004 0.0004
Mycobacterium ulcerans thymidylate synthase 0.3882 0.4723 1
Echinococcus multilocularis metabotropic glutamate receptor 2 0.002 0.0004 0.0004
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0067 0.0061 0.0128
Echinococcus granulosus pyruvate kinase 0.0036 0.0023 0.0023
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.0024 0.0024
Schistosoma mansoni dihydrofolate reductase 0.0043 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0045 0.0034 0.0034
Onchocerca volvulus 0.0049 0.0039 0.0036
Schistosoma mansoni hypothetical protein 0.0051 0.0042 0.0042
Echinococcus granulosus expressed conserved protein 0.0098 0.0099 0.0099
Brugia malayi ImpB/MucB/SamB family protein 0.0128 0.0136 0.0136
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0077 0.0074 0.0414
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0009
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0077 0.0074 0.015
Echinococcus multilocularis sodium and chloride dependent glycine 0.1392 0.168 0.168
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0035 0.0022 0.0022
Schistosoma mansoni glutamate receptor kainate 0.0065 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0095 0.0095 0.0095
Schistosoma mansoni steroid hormone receptor ad4bp 0.0095 0.0095 0.0095
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.1392 0.168 0.168
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0095 0.0095 0.0095
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0039 0.0077
Schistosoma mansoni amine GPCR 0.0239 0.0272 0.0272
Schistosoma mansoni unc-13 (munc13) 0.0035 0.0022 0.0022
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0095 0.0095 0.0095
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0017 0.0017
Onchocerca volvulus 0.005 0.004 0.0037
Leishmania major eukaryotic translation initiation factor-like protein 0.0035 0.0022 0.0045
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0035 0.0022 0.0022
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0003 0.0003
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0307 0.0355 0.0742
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0085 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0037 0.0024 0.0024
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0128 0.0136 0.0136
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0239 0.0272 0.0272
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.037 0.0432 0.0432
Echinococcus granulosus peptide allatostatin:somatostatin 0.0239 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Trichomonas vaginalis mercuric reductase, putative 0.0077 0.0074 0.0317
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0045 0.0034 0.0034
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0095 0.0095 0.0095
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0029 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0095 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Trypanosoma cruzi extracellular receptor, putative 0.002 0.0004 0.0008
Echinococcus granulosus raf serine:threonine protein kinase 0.101 0.1214 0.1214
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0076 0.0073 0.0073
Schistosoma mansoni sex comb on midleg homolog 0.0049 0.0039 0.0039
Echinococcus granulosus dnaJ subfamily B 0.0435 0.0511 0.0511
Echinococcus granulosus nAChR subunit 0.0029 0.0014 0.0014
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0029 0.0014 0.0014
Entamoeba histolytica hypothetical protein 0.0077 0.0073 0.6736
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0022 0.0006 0.0006
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0021 0.0004 0.0003
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0085 0.0083 0.0083
Onchocerca volvulus 0.005 0.004 0.0037
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0009 0.0027
Loa Loa (eye worm) LGC-31 protein 0.0053 0.0044 0.0044
Echinococcus granulosus lysine specific demethylase 5A 0.0036 0.0024 0.0024
Echinococcus granulosus dihydrofolate reductase 0.0043 0.0032 0.0032
Echinococcus granulosus protein kinase c eta type 0.0035 0.0022 0.0022
Brugia malayi CHE-14 protein 0.0045 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0123 0.013 0.013
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0024 0.0009 0.0009
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0077 0.0074 0.0155
Entamoeba histolytica thioredoxin reductase, putative 0.0021 0.0004 0.0122
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.0024 0.0024
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0021 0.0004 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0095 0.0095 0.0095
Giardia lamblia Pyruvate kinase 0.0036 0.0023 0.1673
Echinococcus multilocularis neuropeptide receptor A26 0.4769 0.5807 0.5807
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0021 0.0004 0.0009
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0239 0.0272 0.0272
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0053 0.0044 0.0044
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0021 0.0004 0.0122
Schistosoma mansoni nuclear hormone receptor 0.0045 0.0034 0.0034
Echinococcus multilocularis Diacylglycerol kinase theta 0.0035 0.0022 0.0022
Brugia malayi hypothetical protein 0.0239 0.0272 0.0272
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0019 0.0003 0.0003
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0105 0.0107 1
Trichomonas vaginalis inositol monophosphatase, putative 0.0022 0.0006 0.0012
Trypanosoma cruzi DNA polymerase eta, putative 0.0076 0.0073 0.0151
Echinococcus multilocularis dnaJ subfamily B 0.0435 0.0511 0.0511
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0077 0.0074 0.0155
Brugia malayi Protein kinase c protein 2 0.0035 0.0022 0.0022
Echinococcus multilocularis Major facilitator superfamily, general substrate transporter 0.0148 0.016 0.016
Trypanosoma brucei DNA polymerase kappa, putative 0.0103 0.0106 0.0221
Schistosoma mansoni nAChR subunit 0.0024 0.0009 0.0009
Onchocerca volvulus 0.0053 0.0044 0.0041
Onchocerca volvulus Protein ultraspiracle homolog 0.0095 0.0095 0.0093
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0024 0.0009 0.0009
Plasmodium falciparum glutathione reductase 0.0077 0.0074 0.0155
Echinococcus granulosus ecdysone induced protein 78C 0.0095 0.0095 0.0095
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.1392 0.168 0.168
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.1392 0.168 0.3518
Echinococcus granulosus glycine receptor subunit alpha 1 0.0053 0.0044 0.0044
Schistosoma mansoni hypothetical protein 0.0239 0.0272 0.0272
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0035 0.0022 0.0022
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0077 0.0074 0.015
Schistosoma mansoni amine GPCR 0.0239 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Leishmania major hypothetical protein, conserved 0.0021 0.0004 0.0009
Loa Loa (eye worm) hypothetical protein 0.0095 0.0095 0.0095
Echinococcus multilocularis microtubule associated protein 2 0.0734 0.0876 0.0876
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0039 0.0082
Onchocerca volvulus 0.0239 0.0272 0.0269
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0014
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0077 0.0074 0.0154
Schistosoma mansoni pyruvate kinase 0.0069 0.0064 0.0064
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.3926 0.4776 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0239 0.0272 0.0272
Brugia malayi hypothetical protein 0.005 0.0041 0.0041
Echinococcus multilocularis neuropeptides capa receptor 0.0239 0.0272 0.0272
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.1392 0.168 0.168
Schistosoma mansoni adenoreceptor 0.0239 0.0272 0.0272
Mycobacterium tuberculosis Hypothetical protein 0.1847 0.2236 0.4731
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0566 0.0671 0.1415
Brugia malayi Reduced folate carrier family protein 0.005 0.004 0.004
Schistosoma mansoni acetylcholine receptor-related 0.0024 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0013 0.0027
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.1392 0.168 0.168
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0024 0.0009 0.0009
Trypanosoma cruzi NADH dehydrogenase, putative 0.0021 0.0004 0.0009
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Brugia malayi Cation transporter family protein 0.0053 0.0044 0.0044
Schistosoma mansoni hypothetical protein 0.0035 0.0022 0.0022
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0019 0.0003 0.0003
Echinococcus multilocularis orexin receptor type 2 0.0239 0.0272 0.0272
Echinococcus multilocularis serotonin receptor 0.0239 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Brugia malayi polk-prov protein 0.0051 0.0042 0.0042
Entamoeba histolytica hypothetical protein 0.0035 0.0022 0.1844
Mycobacterium tuberculosis Conserved protein 0.0111 0.0115 0.0237
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0019 0.0003 0.0003
Schistosoma mansoni tyrosine kinase 0.0026 0.0011 0.0011
Onchocerca volvulus 0.0239 0.0272 0.0269
Leishmania major hypothetical protein, conserved 0.0027 0.0013 0.0026
Loa Loa (eye worm) raf kinase 0.1004 0.1206 0.1206
Loa Loa (eye worm) hypothetical protein 0.0035 0.0022 0.0022
Schistosoma mansoni nuclear hormone receptor 0.0095 0.0095 0.0095
Schistosoma mansoni hypothetical protein 0.018 0.02 0.02
Plasmodium falciparum transporter, putative 0.1392 0.168 0.3518
Loa Loa (eye worm) hypothetical protein 0.0053 0.0044 0.0044
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0045 0.0034 0.0034
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0077 0.0074 0.0074
Schistosoma mansoni metabotropic glutamate receptor 0.002 0.0004 0.0004
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0021 0.0004 0.0004
Echinococcus granulosus beta-adrenergic receptor kinase 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0053 0.0044 0.0044
Loa Loa (eye worm) latrophilin receptor protein 2 0.037 0.0432 0.0432
Echinococcus multilocularis beta adrenergic receptor kinase 0.0019 0.0003 0.0003
Schistosoma mansoni cpg binding protein 0.0032 0.0019 0.0019
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0021 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0509 0.0601 0.1268
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0128 0.0136 0.0136
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.1392 0.168 0.3518
Echinococcus granulosus nuclear receptor nhr 48 0.0045 0.0034 0.0034
Brugia malayi Steroid receptor seven-up type 2 0.0095 0.0095 0.0095
Echinococcus granulosus orexin receptor type 2 0.0239 0.0272 0.0272
Echinococcus multilocularis protein patched 0.0045 0.0034 0.0034
Echinococcus granulosus glutamate receptor subunit protein glur 0.0043 0.0032 0.0032
Echinococcus granulosus rhodopsin orphan GPCR 0.0239 0.0272 0.0272
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0239 0.0272 0.0272
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0085 0.0083 0.0083
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0022 0.0022
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0043 0.0032 0.0032
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.012 0.0126 0.0126
Onchocerca volvulus 0.0035 0.0022 0.0019
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.3926 0.4776 1
Schistosoma mansoni pyruvate kinase 0.0069 0.0064 0.0064
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.0044 0.0091
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0021 0.0004 0.0003
Mycobacterium tuberculosis Probable reductase 0.0509 0.0601 0.1268
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0053 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0045 0.0034 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0095 0.0095 0.0095
Echinococcus multilocularis Rac GTPase activating protein 1 0.0035 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.005 0.004 0.004
Schistosoma mansoni neuropeptide F-like receptor 0.0239 0.0272 0.0272
Trypanosoma cruzi pyruvate kinase 2, putative 0.0069 0.0064 0.0134
Loa Loa (eye worm) hypothetical protein 0.1392 0.168 0.168
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0003 0.0003
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0003 0.0003
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0053 0.0044 0.0044
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.3882 0.4723 0.4723
Onchocerca volvulus Huntingtin homolog 0.0062 0.0055 0.0052
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0003 0.0003
Schistosoma mansoni pyruvate kinase 0.0036 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0075 0.0071 0.0148
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0003 0.0003
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.005 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.8201 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0239 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.005 0.004 0.004
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0049 0.0039 0.0077
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0239 0.0272 0.0272
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0095 0.0095 0.0095
Onchocerca volvulus 0.0239 0.0272 0.0269
Schistosoma mansoni sulfide quinone reductase 0.0021 0.0004 0.0004
Onchocerca volvulus 0.0035 0.0022 0.0019
Schistosoma mansoni nuclear receptor 0.0045 0.0034 0.0034
Echinococcus multilocularis nmda type glutamate receptor 0.002 0.0004 0.0004
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0239 0.0272 0.0272
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0029 0.0014 0.0014
Giardia lamblia Hypothetical protein 0.005 0.004 0.3232
Echinococcus multilocularis glycine receptor subunit beta 0.0053 0.0044 0.0044
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0095 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.1392 0.168 0.168
Echinococcus granulosus tm gpcr rhodopsin 0.0239 0.0272 0.0272
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0077 0.0074 0.0155
Loa Loa (eye worm) hypothetical protein 0.0055 0.0047 0.0047
Echinococcus multilocularis unc 13 (munc13) 0.0035 0.0022 0.0022
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0239 0.0272 0.0272
Giardia lamblia Hypothetical protein 0.0111 0.0115 1
Echinococcus granulosus serotonin receptor 0.0239 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0053 0.0044 0.0044
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0003 0.0003
Onchocerca volvulus Folate transporter 1 homolog 0.005 0.004 0.0037
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Schistosoma mansoni hypothetical protein 0.0765 0.0914 0.0914
Loa Loa (eye worm) hypothetical protein 0.0128 0.0136 0.0136
Brugia malayi Guanylyl cyclase protein 23 0.0029 0.0014 0.0014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0239 0.0272 0.0272
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0053 0.0044 0.0044
Schistosoma mansoni acetylcholine receptor subunit beta 0.0024 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0095 0.0095 0.0095
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0035 0.0022 0.0084
Onchocerca volvulus 0.0051 0.0042 0.0039
Loa Loa (eye worm) hypothetical protein 0.0035 0.0022 0.0022
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0053 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0053 0.0044 0.0044
Brugia malayi Dopamine receptor protein 1 0.0239 0.0272 0.0272
Onchocerca volvulus Pyruvate kinase homolog 0.0069 0.0064 0.0061
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0025 0.001 0.0021
Schistosoma mansoni hypothetical protein 0.031 0.0358 0.0358
Echinococcus granulosus sex peptide receptor 0.0239 0.0272 0.0272
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0039 0.0077
Echinococcus granulosus Nuclear hormone receptor HR96 0.0045 0.0034 0.0034
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0021 0.0004 0.0009
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0029 0.0014 0.0014
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0021 0.0004 0.0004
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0021 0.0004 0.0009
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.018 0.02 0.02
Echinococcus granulosus sodium and chloride dependent glycine 0.1392 0.168 0.168
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0021 0.0004 0.0004
Trichomonas vaginalis glutamate synthase, putative 0.0021 0.0004 0.0006
Trichomonas vaginalis ap endonuclease, putative 0.0075 0.0071 0.0305
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0003 0.0003
Brugia malayi acetyltransferase, GNAT family protein 0.0306 0.0354 0.0354
Loa Loa (eye worm) hypothetical protein 0.0045 0.0034 0.0034
Mycobacterium ulcerans hypothetical protein 0.0162 0.0177 0.0369
Brugia malayi sulfakinin receptor protein 0.0239 0.0272 0.0272
Onchocerca volvulus 0.3882 0.4723 0.4722
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0025 0.001 0.0033
Brugia malayi G-protein coupled receptor 0.0239 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0035 0.0022 0.0022
Schistosoma mansoni opsin-like receptor 0.0239 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Echinococcus granulosus dro:myosuppressin receptor 0.0239 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.005 0.004 0.004
Echinococcus granulosus glutamate NMDA receptor subunit 0.0291 0.0335 0.0335
Schistosoma mansoni amine GPCR 0.0239 0.0272 0.0272
Entamoeba histolytica hypothetical protein 0.0029 0.0014 0.1069
Trypanosoma brucei DNA polymerase eta, putative 0.0128 0.0136 0.0285
Onchocerca volvulus 0.0239 0.0272 0.0269
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0009
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0021 0.0004 0.0003
Echinococcus multilocularis N chimaerin 0.0035 0.0022 0.0022
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0025 0.001 0.0006
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0067 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.005 0.004 0.004
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0022 0.0006 0.0011
Loa Loa (eye worm) hypothetical protein 0.005 0.004 0.004
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.009 0.0089 0.0187
Echinococcus granulosus histone lysine methyltransferase setb 0.0019 0.0003 0.0003
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0077 0.0074 0.0155
Trypanosoma cruzi pyruvate kinase 2, putative 0.0069 0.0064 0.0134
Schistosoma mansoni serine/threonine protein kinase 0.101 0.1214 0.1214
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0035 0.0022 0.0045
Echinococcus multilocularis polycomb protein SCMH1 0.0049 0.0039 0.0039
Giardia lamblia DINP protein human, muc B family 0.0082 0.008 0.6825
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0095 0.0095 0.0095
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0045 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0009
Echinococcus granulosus cpg binding protein 0.0032 0.0019 0.0019
Brugia malayi hypothetical protein 0.0077 0.0073 0.0073
Brugia malayi hypothetical protein 0.0239 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0035 0.0022 0.0022
Brugia malayi hypothetical protein 0.0239 0.0272 0.0272
Schistosoma mansoni sodium/chloride dependent transporter 0.1392 0.168 0.168
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.002 0.0004 0.0004
Brugia malayi G protein-coupled receptor 0.0239 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.012 0.0126 0.0126
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0057 0.0049 0.0102
Brugia malayi RhoGAP domain containing protein 0.0035 0.0022 0.0022
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0128 0.0136 0.0136
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0035 0.0022 0.0022
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0021 0.0004 0.0003
Echinococcus multilocularis glycine receptor subunit beta 0.0053 0.0044 0.0044
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0025 0.001 0.0021
Echinococcus multilocularis FTZ F1 alpha 0.0095 0.0095 0.0095
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0076 0.0073 0.0073
Leishmania major extracellular receptor, putative 0.002 0.0004 0.0008
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0035 0.0022 0.0022
Echinococcus multilocularis protein kinase c iota type 0.0035 0.0022 0.0022
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0035 0.0022 0.0022
Schistosoma mansoni glutamate receptor NMDA 0.0085 0.0083 0.0083
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.1392 0.168 0.168
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0022 0.004
Schistosoma mansoni histamine h1 receptor 0.0239 0.0272 0.0272
Brugia malayi Dihydrofolate reductase 0.0043 0.0032 0.0032
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0037 0.0024 0.0118
Onchocerca volvulus 0.0128 0.0136 0.0133
Brugia malayi hypothetical protein 0.0024 0.0009 0.0009
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0025 0.001 0.0015
Loa Loa (eye worm) hypothetical protein 0.0045 0.0034 0.0034
Echinococcus granulosus g-protein coupled receptor 0.0239 0.0272 0.0272
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.1392 0.168 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0239 0.0272 0.0272
Entamoeba histolytica hypothetical protein 0.0077 0.0073 0.6736
Onchocerca volvulus Putative nachr subunit 0.0128 0.0136 0.0133
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0003 0.0003
Brugia malayi conserved hypotetical protein 0.0045 0.0034 0.0034
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0009 0.0009
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0058 0.0058
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0078 0.0075 0.0152
Toxoplasma gondii eukaryotic initiation factor-4E, putative 0.0035 0.0022 0.0046
Entamoeba histolytica hypothetical protein 0.005 0.004 0.3546
Schistosoma mansoni protein kinase C mu 0.0035 0.0022 0.0022
Echinococcus granulosus serotonin transporter 0.8201 1 1
Leishmania major pyruvate kinase 0.0069 0.0064 0.0134
Loa Loa (eye worm) hypothetical protein 0.0051 0.0042 0.0042
Brugia malayi hypothetical protein 0.0239 0.0272 0.0272
Entamoeba histolytica hypothetical protein 0.0025 0.001 0.0659
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0032 0.0067
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0004
Toxoplasma gondii pyruvate kinase PyKII 0.0036 0.0023 0.0048
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0021 0.0004 0.0009
Plasmodium vivax acyl-CoA synthetase, putative 0.0037 0.0024 0.0051
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0053 0.0044 0.0044
Brugia malayi Thioredoxin family protein 0.0111 0.0115 0.0115
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0239 0.0272 0.0272
Echinococcus granulosus Protein patched homolog 1 0.0045 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0014
Echinococcus multilocularis rhodopsin orphan GPCR 0.0239 0.0272 0.0272
Echinococcus multilocularis neuropeptide Y receptor 0.0239 0.0272 0.0272
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0021 0.0004 0.0009
Echinococcus multilocularis raf serine:threonine protein kinase 0.101 0.1214 0.1214
Schistosoma mansoni metabotropic glutamate receptor 0.002 0.0004 0.0004
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0003 0.0003
Echinococcus granulosus hypothetical protein 0.0239 0.0272 0.0272
Entamoeba histolytica diacylglycerol kinase, putative 0.0035 0.0022 0.1844
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0239 0.0272 0.0272
Echinococcus multilocularis nuclear receptor nhr 48 0.0045 0.0034 0.0034
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0239 0.0272 0.0272
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0022 0.0006 0.0012
Brugia malayi ImpB/MucB/SamB family protein 0.0075 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0045 0.0034 0.0034
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0021 0.0004 0.0003
Brugia malayi Ras association domain family 1 isoform A 0.0035 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0009
Onchocerca volvulus 0.0239 0.0272 0.0269
Echinococcus granulosus sodium and chloride dependent glycine 0.1392 0.168 0.168
Trypanosoma brucei DNA polymerase kappa, putative 0.0103 0.0106 0.0221
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0055 0.0047 0.0047
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0076 0.0073 0.0073
Schistosoma mansoni biogenic amine (5HT) receptor 0.0239 0.0272 0.0272
Trypanosoma cruzi DNA polymerase eta, putative 0.0128 0.0136 0.0284
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0039 0.0082
Echinococcus granulosus rhodopsin orphan GPCR 0.0239 0.0272 0.0272
Trypanosoma brucei trypanothione reductase 0.0223 0.0252 0.0528
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.1392 0.168 0.168
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.037 0.0432 0.0432
Brugia malayi Muscleblind-like protein 0.0608 0.0723 0.0723
Echinococcus multilocularis dihydrofolate reductase 0.0043 0.0032 0.0032
Mycobacterium ulcerans hypothetical protein 0.0021 0.0004 0.0003
Loa Loa (eye worm) G-protein coupled receptor 0.0239 0.0272 0.0272
Trypanosoma brucei DNA polymerase kappa, putative 0.0103 0.0106 0.0221
Loa Loa (eye worm) G-protein coupled receptor 0.0239 0.0272 0.0272
Brugia malayi protein kinase C II. 0.0035 0.0022 0.0022
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0034 0.0021 0.0021
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0053 0.0044 0.0044
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0095 0.0095 0.0095
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.037 0.0432 0.0432
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0024 0.0009 0.0009
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0045 0.0034 0.0034
Loa Loa (eye worm) neuropeptide F receptor 0.0239 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0608 0.0723 0.0723
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0032 0.0067
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0021 0.0004 0.0009
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0024 0.0009 0.0009
Echinococcus granulosus Niemann Pick C1 protein 0.0105 0.0107 0.0107
Schistosoma mansoni serine/threonine protein kinase 0.0037 0.0025 0.0025
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0024 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0239 0.0272 0.0272
Plasmodium vivax SET domain protein, putative 0.0019 0.0003 0.0006
Onchocerca volvulus Folate transporter 1 homolog 0.005 0.004 0.0037
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0035 0.0022 0.0022
Echinococcus multilocularis g protein coupled receptor 0.0239 0.0272 0.0272
Echinococcus multilocularis somatostatin receptor 0.0239 0.0272 0.0272
Trypanosoma brucei DNA polymerase kappa, putative 0.0103 0.0106 0.0221
Schistosoma mansoni glutamate receptor NMDA 0.0291 0.0335 0.0335
Mycobacterium tuberculosis Probable oxidoreductase 0.0566 0.0671 0.1415
Brugia malayi PXA domain containing protein 0.0019 0.0003 0.0003
Trypanosoma brucei pyruvate kinase 1, putative 0.0069 0.0064 0.0134
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0021 0.0004 0.0006
Echinococcus multilocularis serotonin receptor 0.0239 0.0272 0.0272
Echinococcus multilocularis G protein coupled receptor 139 0.0395 0.0462 0.0462
Trypanosoma cruzi DNA polymerase kappa, putative 0.0103 0.0106 0.022
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0128 0.0136 0.0136
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0021 0.0004 0.0009
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.1392 0.168 0.168
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0239 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0009
Brugia malayi hypothetical protein 0.0018 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.012 0.0126 0.0126
Schistosoma mansoni jumonji domain containing protein 0.0034 0.0021 0.0021
Onchocerca volvulus 0.0053 0.0044 0.0041
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0239 0.0272 0.0272
Echinococcus multilocularis rhodopsin orphan GPCR 0.0239 0.0272 0.0272
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0026 0.0011 0.0011
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0022 0.0006 0.0011
Echinococcus granulosus thymidylate synthase 0.3882 0.4723 0.4723
Schistosoma mansoni amine GPCR 0.0239 0.0272 0.0272
Echinococcus multilocularis dna polymerase kappa 0.0103 0.0106 0.0106
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0067 0.0061 0.0061
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0077 0.0074 0.0154
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0035 0.0022 0.0084
Brugia malayi metabotropic GABA-B receptor subtype 2 0.002 0.0004 0.0004
Echinococcus granulosus uncharacterized sodium dependent transporter 0.1392 0.168 0.168
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0077 0.0074 1
Plasmodium vivax glutathione reductase, putative 0.0223 0.0252 0.0528
Onchocerca volvulus 0.0024 0.0009 0.0006
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0075 0.0071 0.0144
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.002 0.0004 0.0004
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0024 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Brugia malayi hypothetical protein 0.0019 0.0003 0.0003
Onchocerca volvulus 0.0029 0.0014 0.0011
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0053 0.0044 0.0044
Brugia malayi G-protein coupled receptor 0.0239 0.0272 0.0272
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0077 0.0073 0.0073
Mycobacterium tuberculosis Conserved hypothetical protein 0.0075 0.0071 0.0144
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0021 0.0004 0.0009
Chlamydia trachomatis glutamine binding protein 0.0078 0.0075 0.042
Toxoplasma gondii NADPH-glutathione reductase 0.0077 0.0074 0.0155
Echinococcus multilocularis neuropeptide s receptor 0.4769 0.5807 0.5807
Trypanosoma brucei DNA polymerase kappa, putative 0.0051 0.0042 0.0089
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0053 0.0044 0.0044
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.075 0.0896 0.0896
Loa Loa (eye worm) reduced folate carrier family protein 0.005 0.004 0.004
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0035 0.0022 0.0084
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.005 0.004 0.004
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0145 0.0157 0.0328
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0089 0.0088 0.0088
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0021 0.0004 0.0009
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.005 0.004 0.004
Onchocerca volvulus 0.1392 0.168 0.1678
Loa Loa (eye worm) hypothetical protein 0.0095 0.0095 0.0095
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0049 0.0039 0.0077
Schistosoma mansoni glutamate receptor AMPA 0.0065 0.0058 0.0058
Echinococcus granulosus sterol regulatory element binding protein 0.0045 0.0034 0.0034
Mycobacterium tuberculosis Conserved hypothetical protein 0.0111 0.0115 0.0237
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0022 0.0006 0.0012
Brugia malayi Sodium:neurotransmitter symporter family protein 0.1392 0.168 0.168
Echinococcus multilocularis allatostatin A receptor 0.0239 0.0272 0.0272
Schistosoma mansoni myelin transcription factor 1 myt1 0.0055 0.0047 0.0047
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0021 0.0004 0.0004
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0053 0.0044 0.0044
Plasmodium falciparum pyruvate kinase 2 0.0036 0.0023 0.0048
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0019 0.0003 0.0003
Echinococcus granulosus fmrfamide receptor 0.0239 0.0272 0.0272
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0075 0.0071 0.0071
Mycobacterium ulcerans dehydrogenase 0.0021 0.0004 0.0003
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0095 0.0095 0.0095
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0025 0.001 0.0021
Chlamydia trachomatis dihydrofolate reductase 0.0043 0.0032 0.0165
Loa Loa (eye worm) hypothetical protein 0.0128 0.0136 0.0136
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0021 0.0004 0.0004
Schistosoma mansoni nuclear receptor 0.0045 0.0034 0.0034
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0239 0.0272 0.0272
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0021 0.0004 0.0006
Brugia malayi GnHR receptor homolog 0.0239 0.0272 0.0272
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0053 0.0044 0.0044
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0013 0.0027
Brugia malayi hypothetical protein 0.0045 0.0034 0.0034
Brugia malayi neuropeptide F receptor 0.0239 0.0272 0.0272
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0021 0.0004 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0095 0.0095 0.0095
Echinococcus multilocularis pyruvate kinase 0.0036 0.0023 0.0023
Echinococcus granulosus somatostatin receptor 0.0239 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0095 0.0095 0.0095
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0021 0.0004 0.0004
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0021 0.0004 0.0122
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.3926 0.4776 1
Trypanosoma brucei DNA polymerase IV, putative 0.0103 0.0106 0.0221
Loa Loa (eye worm) hypothetical protein 0.0053 0.0044 0.0044
Brugia malayi Trypsin family protein 0.0105 0.0107 0.0107
Plasmodium vivax pyruvate kinase, putative 0.0069 0.0064 0.0134
Entamoeba histolytica deoxycytidyl transferase, putative 0.0075 0.0071 0.6531
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Onchocerca volvulus 0.0239 0.0272 0.0269
Schistosoma mansoni opsin-like receptor 0.0239 0.0272 0.0272
Brugia malayi hypothetical protein 0.0239 0.0272 0.0272
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0021 0.0004 0.0009
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0053 0.0044 0.0044
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.0044 0.0044
Schistosoma mansoni glutamate synthase 0.0021 0.0004 0.0004
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0077 0.0074 0.0154
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0053 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0035 0.0022 0.0022
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0046 0.0035 0.0032
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0014
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.3882 0.4723 1
Mycobacterium leprae conserved hypothetical protein 0.0025 0.001 0.0015
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0053 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.1392 0.168 0.168
Brugia malayi Nuclear hormone receptor-like 1 0.005 0.0041 0.0041
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0077 0.0074 1
Schistosoma mansoni serine-type protease inhibitor 0.3231 0.3928 0.3928
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0004 0.0009
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0035 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.005 0.0041 0.0041
Loa Loa (eye worm) solute carrier family 6 member 4 0.8201 1 1
Echinococcus multilocularis pyruvate kinase 0.0036 0.0023 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0051 0.0042 0.0089
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0239 0.0272 0.0272
Schistosoma mansoni glutamate synthase 0.0021 0.0004 0.0004
Echinococcus granulosus L aminoadipate semialdehyde 0.0089 0.0088 0.0088
Trypanosoma cruzi trypanothione reductase, putative 0.0077 0.0074 0.0154
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0061 0.0123
Brugia malayi excitatory GABA receptor EXP-1A 0.0053 0.0044 0.0044
Echinococcus granulosus protein kinase c epsilon type 0.0035 0.0022 0.0022
Brugia malayi RhoGAP domain containing protein 0.0035 0.0022 0.0022
Echinococcus granulosus rhodopsin orphan GPCR 0.0239 0.0272 0.0272
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0051 0.0107
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0095 0.0095 0.0095
Brugia malayi dihydrofolate reductase family protein 0.0043 0.0032 0.0032
Brugia malayi follicle stimulating hormone receptor 0.0239 0.0272 0.0272
Echinococcus granulosus thioredoxin glutathione reductase 0.0224 0.0253 0.0253
Treponema pallidum sodium- and chloride- dependent transporter 0.8201 1 1
Trypanosoma brucei NADH dehydrogenase 0.0021 0.0004 0.0009
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0145 0.0157 0.0329
Schistosoma mansoni alpha-1 adrenergic receptor 0.0239 0.0272 0.0272
Schistosoma mansoni hypothetical protein 0.0077 0.0073 0.0073
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0239 0.0272 0.0272
Brugia malayi Sodium:neurotransmitter symporter family protein 0.1392 0.168 0.168
Toxoplasma gondii exonuclease III APE 0.0075 0.0071 0.0149
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Trypanosoma brucei DNA polymerase IV, putative 0.0096 0.0097 0.0203
Loa Loa (eye worm) acetyltransferase 0.0306 0.0354 0.0354
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.0044 0.0044
Mycobacterium tuberculosis Hypothetical protein 0.0111 0.0115 0.0237
Brugia malayi Inositol-1 0.0022 0.0006 0.0006
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0075 0.0071 0.0149
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0034 0.0021 0.0021
Echinococcus multilocularis thyroid hormone receptor alpha 0.0095 0.0095 0.0095
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0509 0.0601 0.1268
Loa Loa (eye worm) hypothetical protein 0.0037 0.0024 0.0024
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0019 0.0003 0.0003
Onchocerca volvulus 0.1392 0.168 0.1678
Brugia malayi neuropeptide F receptor 0.0239 0.0272 0.0272
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0077 0.0074 0.0074
Schistosoma mansoni nAChR subunit 0.0053 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0045 0.0034 0.0034
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0077 0.0074 0.0155
Schistosoma mansoni neurotransmitter gated ion channel 0.0024 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.005 0.0041 0.0041
Onchocerca volvulus 0.0239 0.0272 0.0269
Echinococcus granulosus neuropeptides capa receptor 0.0239 0.0272 0.0272
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0239 0.0272 0.0272
Schistosoma mansoni glutamate receptor AMPA 0.0065 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.8201 1 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0061 0.0123
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.0039 0.0077
Schistosoma mansoni sodium/chloride dependent transporter 0.8201 1 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Echinococcus multilocularis glutamate receptor 2 0.0042 0.003 0.003
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0021 0.0004 0.0003
Echinococcus granulosus survival motor neuron protein 1 0.0251 0.0287 0.0287
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.1392 0.168 0.168
Chlamydia trachomatis pyruvate kinase 0.0069 0.0064 0.0356
Plasmodium falciparum ferrodoxin reductase-like protein 0.0021 0.0004 0.0009
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.1392 0.168 0.168
Echinococcus multilocularis nAChR subunit 0.0053 0.0044 0.0044
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0075 0.0071 0.0071
Loa Loa (eye worm) RGC/RGC protein kinase 0.0029 0.0014 0.0014
Trypanosoma brucei DNA damage repair protein, putative 0.0023 0.0008 0.0016
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Echinococcus granulosus inositol monophosphatase 1 0.0022 0.0006 0.0006
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0307 0.0355 0.0743
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Brugia malayi protein kinase C3,putative 0.0035 0.0022 0.0022
Toxoplasma gondii hypothetical protein 0.005 0.004 0.0084
Echinococcus multilocularis neuropeptide receptor 0.0239 0.0272 0.0272
Toxoplasma gondii pyruvate kinase PyK1 0.0069 0.0064 0.0134
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0077 0.0073 0.0073
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0021 0.0004 0.0004
Echinococcus granulosus uncharacterized sodium dependent transporter 0.1392 0.168 0.168
Trichomonas vaginalis apoptosis inducing factor, putative 0.0021 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.8201 1 1
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0077 0.0074 0.0154
Loa Loa (eye worm) norepinephrine transporter 0.8201 1 1
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0022 0.0006 0.0012
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0021 0.0004 0.0004
Onchocerca volvulus 0.0239 0.0272 0.0269
Loa Loa (eye worm) hypothetical protein 0.0049 0.0039 0.0039
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0055 0.0047 0.0047
Brugia malayi metabotropic glutamate receptor type 2 0.002 0.0004 0.0004
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0035 0.0022 0.0084
Brugia malayi jmjC domain containing protein 0.0034 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0048 0.0039 0.0039
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0019 0.0003 0.0003
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0307 0.0355 0.0742
Onchocerca volvulus 0.8201 1 1
Trypanosoma cruzi DNA damage repair protein, putative 0.0023 0.0008 0.0016
Echinococcus granulosus biogenic amine 5HT receptor 0.0239 0.0272 0.0272
Schistosoma mansoni hypothetical protein 0.0043 0.0032 0.0032
Schistosoma mansoni amine GPCR 0.0239 0.0272 0.0272
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0021 0.0004 0.0009
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0023 0.0008 0.0016
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0053 0.0044 0.0044
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0003 0.0003
Brugia malayi mbt repeat family protein 0.0049 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Brugia malayi latrophilin 2 splice variant baaae 0.0765 0.0914 0.0914
Schistosoma mansoni protein kinase C mu 0.0035 0.0022 0.0022
Brugia malayi Cation transporter family protein 0.0053 0.0044 0.0044
Schistosoma mansoni DNA polymerase IV / kappa 0.0023 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0021 0.0004 0.0009
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0053 0.0044 0.0044
Onchocerca volvulus 0.0239 0.0272 0.0269
Schistosoma mansoni hypothetical protein 0.0043 0.0032 0.0032
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0095 0.0095 0.0095
Schistosoma mansoni serine-type protease inhibitor 0.3231 0.3928 0.3928
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0043 0.0032 0.0032
Echinococcus multilocularis g protein coupled receptor 0.0239 0.0272 0.0272
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0053 0.0044 0.0044
Echinococcus multilocularis rhodopsin orphan GPCR 0.0239 0.0272 0.0272
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0035 0.0022 0.0022
Brugia malayi Pyruvate kinase, muscle isozyme 0.0069 0.0064 0.0064
Echinococcus granulosus protein kinase c iota type 0.0035 0.0022 0.0022
Giardia lamblia DNA damage repair protein 0.0023 0.0008 0.0309
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0095 0.0095 0.0093
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0008 0.0016
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0021 0.0004 0.0006
Giardia lamblia NADH oxidase lateral transfer candidate 0.0077 0.0074 0.6295
Loa Loa (eye worm) hypothetical protein 0.0045 0.0034 0.0034
Mycobacterium ulcerans glutamate synthase subunit beta 0.0021 0.0004 0.0003
Leishmania major eukaryotic translation initiation factor eIF-4E, putative 0.0035 0.0022 0.0045
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0006 0.0012
Echinococcus multilocularis G-protein coupled receptor, putative 0.0239 0.0272 0.0272
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0053 0.0044 0.0044
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0043 0.0032 0.0032
Echinococcus granulosus N chimaerin 0.0035 0.0022 0.0022
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.005 0.0041 0.0041
Schistosoma mansoni hypothetical protein 0.0208 0.0233 0.0233
Echinococcus multilocularis tyrosine kinase 0.0026 0.0011 0.0011
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0037 0.0024 0.0045
Echinococcus granulosus histone acetyltransferase MYST2 0.0055 0.0047 0.0047
Echinococcus granulosus pyruvate kinase 0.0069 0.0064 0.0064
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0003 0.0003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0077 0.0074 0.0154
Loa Loa (eye worm) thioredoxin reductase 0.0223 0.0252 0.0252
Toxoplasma gondii selenide, water dikinase 0.0021 0.0004 0.0009
Loa Loa (eye worm) hypothetical protein 0.0049 0.0039 0.0039
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Schistosoma mansoni DNA polymerase eta 0.0128 0.0136 0.0136
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0095 0.0095 0.0095
Onchocerca volvulus 0.0111 0.0115 0.0112
Onchocerca volvulus 0.0095 0.0095 0.0093
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0009
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0043 0.0032 0.0067
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.0039 0.3478
Loa Loa (eye worm) GABA receptor subunit 0.0029 0.0014 0.0014
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0239 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Onchocerca volvulus 0.0053 0.0044 0.0041
Brugia malayi hypothetical protein 0.0239 0.0272 0.0272
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0035 0.0022 0.0045
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0008 0.0016
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0239 0.0272 0.0272
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0077 0.0074 0.0155
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0025 0.001 0.0021
Echinococcus granulosus rhodopsin orphan GPCR 0.0239 0.0272 0.0272
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0053 0.0044 0.0044
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0003 0.0003
Echinococcus granulosus FTZ F1 alpha 0.0095 0.0095 0.0095
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.037 0.0432 0.0432
Echinococcus multilocularis expressed conserved protein 0.0098 0.0099 0.0099
Brugia malayi hypothetical protein 0.0027 0.0013 0.0013
Echinococcus granulosus muscleblind protein 0.0608 0.0723 0.0723
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0004 0.0009
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0021 0.0004 0.0009
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.0039 0.0077
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.005 0.004 0.004
Mycobacterium ulcerans hypothetical protein 0.0111 0.0115 0.0236
Onchocerca volvulus 0.002 0.0004 0.0001
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0566 0.0671 0.1415
Leishmania major hypothetical protein, conserved 0.0021 0.0004 0.0009
Echinococcus multilocularis glutamate receptor 2 0.0085 0.0083 0.0083
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0247 0.0281 0.0281
Loa Loa (eye worm) hypothetical protein 0.0045 0.0034 0.0034
Echinococcus multilocularis snurportin 1 0.018 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.005 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0003 0.0003
Echinococcus granulosus tm gpcr rhodopsin 0.0239 0.0272 0.0272
Plasmodium vivax thioredoxin reductase, putative 0.0223 0.0252 0.0528
Brugia malayi RhoGEF domain containing protein 0.0035 0.0022 0.0022
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0039 0.0039
Schistosoma mansoni hypothetical protein 0.0111 0.0115 0.0115
Echinococcus multilocularis rhodopsin orphan GPCR 0.0239 0.0272 0.0272
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0082 0.008 0.0166
Loa Loa (eye worm) hypothetical protein 0.1392 0.168 0.168
Trichomonas vaginalis glutathione reductase, putative 0.0077 0.0074 0.0317
Loa Loa (eye worm) hypothetical protein 0.0062 0.0055 0.0055
Echinococcus multilocularis histone acetyltransferase MYST2 0.0055 0.0047 0.0047
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0037 0.0024 0.0045
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.0039 0.0077
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0075 0.0071 0.0144
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0058 0.0058
Plasmodium vivax ferrodoxin reductase, putative 0.0021 0.0004 0.0009
Brugia malayi Receptor family ligand binding region containing protein 0.0046 0.0035 0.0035
Echinococcus granulosus rhodopsin orphan GPCR 0.0239 0.0272 0.0272
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0029 0.0014 0.0014
Schistosoma mansoni vav2 0.0035 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.005 0.004 0.004
Echinococcus multilocularis nAChR subunit 0.0029 0.0014 0.0014
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0045 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0009
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0003 0.0003
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0057 0.0049 0.0049
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.1847 0.2236 0.4682
Schistosoma mansoni coup transcription factor 0.0095 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0008 0.0016
Loa Loa (eye worm) hypothetical protein 0.0045 0.0034 0.0034
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.001 0.0021
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0239 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0009
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0003 0.0003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0239 0.0272 0.0272
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0019 0.0003 0.0006
Schistosoma mansoni thyroid hormone receptor 0.0095 0.0095 0.0095
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0043 0.0032 0.0062
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0058 0.0058
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0076 0.0073 0.0073
Loa Loa (eye worm) melatonin receptor type 1A 0.0239 0.0272 0.0272
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0055 0.0047 0.0047
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0095 0.0095 0.0095
Echinococcus granulosus g protein coupled receptor 0.0239 0.0272 0.0272
Onchocerca volvulus Pyruvate kinase homolog 0.0069 0.0064 0.0061
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0239 0.0272 0.0272
Echinococcus granulosus biogenic amine 5HT receptor 0.0239 0.0272 0.0272
Giardia lamblia Transglutaminase/protease, putative 0.0111 0.0115 1
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0024 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0057 0.0049 0.0049
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0057 0.0049 0.0049
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0053 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.1392 0.168 0.168
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0022 0.0006 0.0196
Loa Loa (eye worm) pyruvate kinase 0.0069 0.0064 0.0064
Brugia malayi thymidylate synthase 0.3882 0.4723 0.4723
Loa Loa (eye worm) hypothetical protein 0.0049 0.0039 0.0039
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0128 0.0136 0.0136
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0095 0.0095 0.0095
Echinococcus multilocularis cpg binding protein 0.0032 0.0019 0.0019
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0075 0.0071 0.0148
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0085 0.0083 0.0083
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0053 0.0044 0.0044
Echinococcus granulosus g protein coupled receptor 0.0239 0.0272 0.0272
Schistosoma mansoni hypothetical protein 0.0239 0.0272 0.0272
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0003 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0095 0.0095 0.0095
Schistosoma mansoni hypothetical protein 0.0043 0.0032 0.0032
Schistosoma mansoni neuropeptide receptor 0.0239 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0095 0.0095 0.0095
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0003 0.0003
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0021 0.0004 0.0004
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0035 0.0022 0.0022
Brugia malayi G protein-coupled receptor F59B2.13 0.0239 0.0272 0.0272
Brugia malayi nuclear hormone receptor 0.0095 0.0095 0.0095
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.3926 0.4776 1
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0053 0.0044 0.0044
Brugia malayi nuclear receptor NHR-67 0.0045 0.0034 0.0034
Schistosoma mansoni hypothetical protein 0.037 0.0432 0.0432
Loa Loa (eye worm) hypothetical protein 0.0053 0.0044 0.0044
Schistosoma mansoni nAChR subunit 0.0053 0.0044 0.0044
Mycobacterium ulcerans hypothetical protein 0.0023 0.0008 0.001
Schistosoma mansoni biogenic amine receptor 0.0239 0.0272 0.0272
Trypanosoma brucei chrX additional, unordered contigs 0.0023 0.0008 0.0016
Echinococcus granulosus glutamate receptor 2 0.0085 0.0083 0.0083
Schistosoma mansoni glutamate receptor kainate 0.0065 0.0058 0.0058
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0077 0.0074 0.015
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0095 0.0095 0.0095
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.0044 0.0044
Schistosoma mansoni nAChR subunit 0.0053 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0045 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0062 0.0055 0.0055
Echinococcus multilocularis protein dispatched 1 0.0051 0.0042 0.0042
Schistosoma mansoni nAChR subunit 0.0053 0.0044 0.0044
Leishmania major pyruvate kinase 0.0069 0.0064 0.0134
Brugia malayi Nuclear hormone receptor-like 1 0.005 0.0041 0.0041
Entamoeba histolytica hypothetical protein 0.0077 0.0073 0.6736
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0075 0.0071 0.0071
Brugia malayi nuclear receptor RXR 0.0045 0.0034 0.0034
Onchocerca volvulus 0.0049 0.0039 0.0036
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0076 0.0073 0.0073
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0003 0.0003
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0053 0.0044 0.0044
Trypanosoma brucei DNA polymerase kappa, putative 0.0103 0.0106 0.0221
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0095 0.0095 0.0095
Loa Loa (eye worm) RecQ helicase 0.0024 0.0009 0.0009
Loa Loa (eye worm) acetylcholine receptor protein 0.0024 0.0009 0.0009
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0095 0.0095 0.0095
Echinococcus multilocularis protein kinase c epsilon type 0.0035 0.0022 0.0022
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.3882 0.4723 1
Brugia malayi nuclear receptor NHR-88 0.0095 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0053 0.0044 0.0044
Onchocerca volvulus Bile acid receptor homolog 0.0095 0.0095 0.0093
Leishmania major DNA polymerase kappa, putative 0.0082 0.008 0.0166
Echinococcus granulosus tumor protein p63 0.0359 0.0418 0.0418
Schistosoma mansoni biogenic amine receptor 0.0239 0.0272 0.0272
Schistosoma mansoni sulfide quinone reductase 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.005 0.0041 0.0041
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0035 0.0022 0.0022
Loa Loa (eye worm) RGC/RGC protein kinase 0.0046 0.0035 0.0035
Schistosoma mansoni thyroid hormone receptor 0.0095 0.0095 0.0095
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0013 0.0027
Brugia malayi nuclear hormone receptor family member odr-7 0.0045 0.0034 0.0034
Leishmania major DNA damage repair protein, putative 0.0023 0.0008 0.0016
Plasmodium falciparum thioredoxin reductase 0.0077 0.0074 0.0155
Trypanosoma cruzi DNA damage repair protein, putative 0.0023 0.0008 0.0016
Loa Loa (eye worm) hypothetical protein 0.0037 0.0024 0.0024
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0077 0.0074 0.0074
Echinococcus multilocularis serotonin transporter 0.8201 1 1
Plasmodium vivax amine transporter, putative 0.1392 0.168 0.3518
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.012 0.0126 0.0126
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0077 0.0074 0.015
Schistosoma mansoni hypothetical protein 0.0435 0.0511 0.0511
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0095 0.0095 0.0095
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0057 0.0049 0.0049
Echinococcus granulosus pyruvate kinase 0.0069 0.0064 0.0064
Onchocerca volvulus 0.0239 0.0272 0.0269
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0043 0.0032 0.0032
Echinococcus granulosus Transglutaminase 0.0111 0.0115 0.0115
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0039 0.0077
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0076 0.0073 0.0073
Echinococcus multilocularis thymidylate synthase 0.3882 0.4723 0.4723
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0075 0.0071 0.0149
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0053 0.0044 0.0044
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0049 0.0039 0.0077
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0049 0.0039 0.0036
Loa Loa (eye worm) pyruvate kinase 0.0069 0.0064 0.0064
Trichomonas vaginalis pyruvate kinase, putative 0.0069 0.0064 0.0273
Loa Loa (eye worm) hypothetical protein 0.0095 0.0095 0.0095
Echinococcus granulosus eukaryotic translation initiation factor 4E 0.0035 0.0022 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0034 0.0139
Echinococcus granulosus 7tm_1 domain containing protein 0.0239 0.0272 0.0272
Brugia malayi AKH receptor 0.0239 0.0272 0.0272
Trypanosoma brucei DNA polymerase kappa, putative 0.0103 0.0106 0.0221
Echinococcus multilocularis SAM and MBT domain containing protein 0.0049 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0045 0.0034 0.0034
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0077 0.0074 0.0154
Schistosoma mansoni opsin-like receptor 0.0239 0.0272 0.0272
Onchocerca volvulus 0.0239 0.0272 0.0269
Brugia malayi Tachykinin-like peptides receptor 99D 0.0239 0.0272 0.0272
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.8201 1 1
Leishmania major phosphopantetheinyl transferase-like protein 0.0025 0.001 0.002
Onchocerca volvulus Neuropeptide F receptor homolog 0.0239 0.0272 0.0269
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0022 0.0006 0.0012
Echinococcus multilocularis ecdysone induced protein 78C 0.0095 0.0095 0.0095
Loa Loa (eye worm) RGC/RGC protein kinase 0.0046 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.005 0.004 0.004
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0095 0.0095 0.0095
Schistosoma mansoni microtubule-associated protein tau 0.0734 0.0876 0.0876
Schistosoma mansoni neuropeptide f receptor 76f 0.0239 0.0272 0.0272
Onchocerca volvulus 0.0053 0.0044 0.0041
Loa Loa (eye worm) TYRA-2 protein 0.0239 0.0272 0.0272
Schistosoma mansoni diacylglycerol kinase theta 0.0035 0.0022 0.0022
Schistosoma mansoni apoptosis regulator bax 0.012 0.0126 0.0126
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0021 0.0004 0.0004
Onchocerca volvulus 0.0045 0.0034 0.0031
Mycobacterium tuberculosis Conserved hypothetical protein 0.0162 0.0177 0.0369
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0024 0.0009 0.0009
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0003 0.0003
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0021 0.0004 0.0004
Loa Loa (eye worm) neuropeptide F receptor 0.0239 0.0272 0.0272
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0035 0.0022 0.1792
Echinococcus granulosus folate receptor beta 0.0821 0.0983 0.0983
Loa Loa (eye worm) hypothetical protein 0.0049 0.0039 0.0039
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0124 0.0131 0.0131
Onchocerca volvulus 0.1392 0.168 0.1678
Loa Loa (eye worm) glutamate receptor 2 0.0065 0.0058 0.0058
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0076 0.0073 0.0073
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0085 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0035 0.0022 0.0022
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0021 0.0004 0.0009
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Loa Loa (eye worm) pyruvate kinase-PB 0.0048 0.0039 0.0039
Loa Loa (eye worm) glutathione reductase 0.0223 0.0252 0.0252
Trichomonas vaginalis pyruvate kinase, putative 0.0069 0.0064 0.0273
Echinococcus granulosus neuropeptide FF receptor 2 0.0239 0.0272 0.0272
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0021 0.0004 0.0009
Brugia malayi Sodium:neurotransmitter symporter family protein 0.1392 0.168 0.168
Schistosoma mansoni ATP-binding cassette transporter 0.0065 0.0058 0.0058
Brugia malayi hypothetical protein 0.002 0.0004 0.0004
Schistosoma mansoni neuropeptide receptor 0.0239 0.0272 0.0272
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0206 0.0232 0.0232
Brugia malayi diacylglycerol kinase 0.0035 0.0022 0.0022
Echinococcus granulosus myotubularin protein 13 0.0035 0.0022 0.0022
Giardia lamblia Pyruvate kinase 0.0069 0.0064 0.5416
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0239 0.0272 0.0272
Brugia malayi Latrophilin receptor protein 2 0.037 0.0432 0.0432
Schistosoma mansoni protein kinase 0.0046 0.0035 0.0035
Brugia malayi ecdysone receptor 0.0045 0.0034 0.0034
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.2462 0.2988 0.2988
Echinococcus multilocularis myotubularin protein 13 0.0035 0.0022 0.0022
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.0044 0.0044
Brugia malayi Dopamine receptor protein 2 0.0239 0.0272 0.0272
Loa Loa (eye worm) thymidylate synthase 0.3882 0.4723 0.4723
Echinococcus granulosus neuropeptide Y receptor 0.0239 0.0272 0.0272
Schistosoma mansoni hypothetical protein 0.0239 0.0272 0.0272
Onchocerca volvulus 0.0239 0.0272 0.0269
Trichomonas vaginalis ap endonuclease, putative 0.0075 0.0071 0.0305
Brugia malayi Nuclear hormone receptor E75 0.0045 0.0034 0.0034
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0022 0.0022
Echinococcus multilocularis rhodopsin orphan GPCR 0.0239 0.0272 0.0272
Loa Loa (eye worm) DR-78 0.0045 0.0034 0.0034
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0095 0.0095 0.0095
Echinococcus granulosus receptor type guanylyl cyclase 0.0046 0.0035 0.0035
Echinococcus granulosus atrial natriuretic peptide receptor 0.0037 0.0025 0.0025
Echinococcus granulosus dna polymerase kappa 0.0103 0.0106 0.0106
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0509 0.0601 0.1268
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0509 0.0601 0.1268
Plasmodium falciparum DNA repair protein REV1, putative 0.0023 0.0008 0.0016
Echinococcus granulosus glutamate synthase 0.0021 0.0004 0.0004
Brugia malayi Receptor family ligand binding region containing protein 0.002 0.0004 0.0004
Echinococcus granulosus Rac GTPase activating protein 1 0.0035 0.0022 0.0022
Echinococcus granulosus glycine receptor subunit beta 0.0053 0.0044 0.0044
Echinococcus granulosus Nuclear hormone receptor HR96 0.0045 0.0034 0.0034
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0053 0.0044 0.0044
Brugia malayi hypothetical protein 0.005 0.0041 0.0041
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.1392 0.168 0.3518
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0051 0.0107
Brugia malayi nuclear hormone receptor family member nhr-6 0.0045 0.0034 0.0034
Trichomonas vaginalis DNA polymerase eta, putative 0.0103 0.0106 0.0459
Loa Loa (eye worm) nuclear hormone receptor 0.0045 0.0034 0.0034
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0021 0.0004 0.0003
Loa Loa (eye worm) ACC-1 protein 0.0053 0.0044 0.0044
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0022 0.004
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Schistosoma mansoni nuclear hormone receptor 0.0045 0.0034 0.0034
Echinococcus granulosus tar DNA binding protein 0.0064 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0069 0.0064 0.0064
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0121 0.0128 0.0128
Schistosoma mansoni nAChR subunit 0.0053 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Onchocerca volvulus 0.0092 0.0092 0.0089
Brugia malayi RE15519p 0.0239 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0095 0.0095 0.0095
Schistosoma mansoni eukaryotic translation initiation factor 4e 0.0035 0.0022 0.0022
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0239 0.0272 0.0272
Echinococcus multilocularis survival motor neuron protein 1 0.0251 0.0287 0.0287
Loa Loa (eye worm) hypothetical protein 0.0095 0.0095 0.0095
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.012 0.0126 0.0126
Trypanosoma brucei RNA helicase, putative 0.0208 0.0233 0.0488
Echinococcus multilocularis rhodopsin orphan GPCR 0.0239 0.0272 0.0272
Entamoeba histolytica hypothetical protein 0.0077 0.0073 0.6736
Echinococcus granulosus geminin 0.0534 0.0632 0.0632
Echinococcus granulosus g protein coupled receptor 0.0239 0.0272 0.0272
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0003 0.0003
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0075 0.0071 0.6533
Plasmodium falciparum histone acetyltransferase GCN5 0.0083 0.008 0.0168
Echinococcus granulosus rhodopsin orphan GPCR 0.0239 0.0272 0.0272
Brugia malayi Pre-SET motif family protein 0.0019 0.0003 0.0003
Brugia malayi Niemann-Pick C1 protein precursor 0.0105 0.0107 0.0107
Brugia malayi Pre-SET motif family protein 0.0124 0.0131 0.0131
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0239 0.0272 0.0272
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0035 0.0022 0.0022
Brugia malayi ecdysteroid receptor 0.0095 0.0095 0.0095
Echinococcus granulosus unc 13 munc13 0.0035 0.0022 0.0022
Echinococcus multilocularis nmda type glutamate receptor 0.0121 0.0128 0.0128
Echinococcus granulosus neuropeptide Y receptor 0.0239 0.0272 0.0272
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0053 0.0044 0.0044
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0021 0.0004 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0095 0.0095 0.0095
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.005 0.004 0.004
Echinococcus multilocularis g-protein coupled receptor 0.0239 0.0272 0.0272
Onchocerca volvulus 0.0089 0.0088 0.0086
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0003 0.0003
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0021 0.0004 0.0009
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0024 0.0009 0.0009
Echinococcus granulosus histone lysine N methyltransferase NSD3 0.0035 0.0022 0.0022
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0021 0.0005 0.0005
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0003 0.0003
Trichomonas vaginalis set domain proteins, putative 0.0141 0.0151 0.0663
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.3926 0.4776 1
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0239 0.0272 0.0272
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0051 0.0107
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.1898 0.2299 0.2299
Brugia malayi hypothetical protein 0.0062 0.0055 0.0055
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0021 0.0004 0.0122
Schistosoma mansoni ap endonuclease 0.0075 0.0071 0.0071
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0053 0.0044 0.0044
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0022 0.0022
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0085 0.0083 0.0083
Echinococcus granulosus glycine receptor subunit beta 0.0053 0.0044 0.0044
Loa Loa (eye worm) hypothetical protein 0.0105 0.0107 0.0107
Echinococcus granulosus polycomb protein SCMH1 0.0049 0.0039 0.0039
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0077 0.0074 0.0154
Trichomonas vaginalis conserved hypothetical protein 0.1847 0.2236 1
Brugia malayi putative neuropeptide receptor NPR1 0.0239 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Trypanosoma brucei DNA damage repair protein, putative 0.0023 0.0008 0.0016
Brugia malayi Raf kinase 0.0975 0.1171 0.1171
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0003 0.0003
Loa Loa (eye worm) dihydrofolate reductase 0.0043 0.0032 0.0032
Echinococcus granulosus pyruvate kinase 0.0036 0.0023 0.0023
Schistosoma mansoni inositol monophosphatase 0.0022 0.0006 0.0006
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0306 0.0354 0.0354
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0049 0.0039 0.0039
Brugia malayi putative neuropeptide receptor 0.0239 0.0272 0.0272
Brugia malayi Melatonin receptor type 1A 0.0239 0.0272 0.0272
Trypanosoma brucei Eukaryotic translation initiation factor 4E-1 0.0035 0.0022 0.0046
Schistosoma mansoni hypothetical protein 0.037 0.0432 0.0432
Brugia malayi hypothetical protein 0.0239 0.0272 0.0272
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0095 0.0095 0.0095
Schistosoma mansoni nuclear receptor nhr-48 0.0045 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0029 0.0014 0.0014
Mycobacterium leprae Probable pyruvate kinase PykA 0.0069 0.0064 0.013
Loa Loa (eye worm) hypothetical protein 0.005 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Schistosoma mansoni SET domain protein 0.0035 0.0022 0.0022
Echinococcus multilocularis rhodopsin orphan GPCR 0.0239 0.0272 0.0272
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0128 0.0136 0.0136
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0239 0.0272 0.0272
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0021 0.0004 0.0004
Echinococcus multilocularis GPCR, family 2 0.037 0.0432 0.0432
Leishmania major dihydrofolate reductase-thymidylate synthase 0.3926 0.4776 1
Plasmodium falciparum acyl-CoA synthetase 0.0037 0.0024 0.0051
Loa Loa (eye worm) hypothetical protein 0.0089 0.0088 0.0088
Leishmania major NADH dehydrogenase, putative 0.0021 0.0004 0.0009
Schistosoma mansoni biogenic amine (5HT) receptor 0.0239 0.0272 0.0272
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0239 0.0272 0.0272
Schistosoma mansoni disulfide oxidoreductase 0.0021 0.0004 0.0004
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0035 0.0022 0.0022
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0045 0.0034 0.0031
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0573 0.068 0.068
Brugia malayi hypothetical protein 0.0239 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.005 0.004 0.004
Onchocerca volvulus 0.0239 0.0272 0.0269
Brugia malayi Glutamate receptor 1 precursor 0.0065 0.0058 0.0058
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0239 0.0272 0.0272
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0239 0.0272 0.0272
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0089 0.0088 0.0088
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0021 0.0004 0.0003
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.0039 0.3478
Schistosoma mansoni biogenic amine receptor 0.0239 0.0272 0.0272
Echinococcus multilocularis glutamate synthase 0.0021 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0251 0.0287 0.0287
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0128 0.0136 0.0136
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0003 0.0003
Echinococcus multilocularis L aminoadipate semialdehyde 0.0089 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0035 0.0022 0.0022
Trypanosoma brucei DNA polymerase IV, putative 0.0103 0.0106 0.0221
Brugia malayi C1-like domain containing protein 0.0035 0.0022 0.0022
Brugia malayi nuclear receptor NHR-88 0.0045 0.0034 0.0034
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0095 0.0095 0.0095
Brugia malayi tailless protein 0.0045 0.0034 0.0034
Schistosoma mansoni hypothetical protein 0.0534 0.0632 0.0632
Loa Loa (eye worm) hypothetical protein 0.0608 0.0723 0.0723
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0003
Onchocerca volvulus 0.0035 0.0022 0.0019
Onchocerca volvulus 0.0239 0.0272 0.0269
Brugia malayi Cation transporter family protein 0.0128 0.0136 0.0136
Echinococcus granulosus nmda type glutamate receptor 0.0121 0.0128 0.0128
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0008 0.0016
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0043 0.0032 0.0062
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0021 0.0004 0.0003
Entamoeba histolytica acetyltransferase, GNAT family 0.0083 0.008 0.7409
Loa Loa (eye worm) hypothetical protein 0.0239 0.0272 0.0272
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0075 0.0071 0.0071
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0022 0.0006 0.0253
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0239 0.0272 0.0272
Trypanosoma cruzi DNA polymerase kappa, putative 0.0103 0.0106 0.022
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0078 0.0075 0.007
Brugia malayi Protein kinase domain containing protein 0.0035 0.0022 0.0022
Loa Loa (eye worm) nuclear receptor NHR-67 0.0045 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0105 0.0107 0.0107
Schistosoma mansoni terminal deoxycytidyl transferase 0.0075 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0027 0.0013 0.0013
Plasmodium vivax hypothetical protein, conserved 0.1392 0.168 0.3518
Schistosoma mansoni diacylglycerol kinase theta 0.0035 0.0022 0.0022
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0019 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0095 0.0095 0.0095
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0095 0.0095 0.0095
Echinococcus multilocularis fmrfamide receptor 0.0239 0.0272 0.0272
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0021 0.0004 0.0003
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0025 0.001 0.0015
Toxoplasma gondii hypothetical protein 0.1392 0.168 0.3518
Brugia malayi diacylglycerol kinase 0.0035 0.0022 0.0022
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0049 0.0039 0.0077
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0003 0.0003
Mycobacterium tuberculosis Long conserved protein 0.0111 0.0115 0.0237
Brugia malayi Dopamine receptor 0.0239 0.0272 0.0272
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0069 0.0064 0.013
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0021 0.0004 0.0003
Echinococcus granulosus histone acetyltransferase KAT2B 0.0298 0.0343 0.0343
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.0061 0.0061
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.1392 0.168 0.168
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0021 0.0004 0.0009
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.1697 0.2053 0.2053
Loa Loa (eye worm) hypothetical protein 0.2462 0.2988 0.2988
Echinococcus granulosus neuropeptide receptor A26 0.4769 0.5807 0.5807
Brugia malayi hypothetical protein 0.0239 0.0272 0.0272
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0021 0.0004 0.0006
Schistosoma mansoni serine/threonine protein kinase 0.0035 0.0022 0.0022
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0239 0.0272 0.0272
Brugia malayi hypothetical protein 0.0024 0.0009 0.0009
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0045 0.0034 0.0034
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0053 0.0044 0.0044
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0037 0.0025 0.0025
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0057 0.0049 0.4
Brugia malayi nuclear receptor RXR 0.005 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0037 0.0024 0.0024
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0035 0.0022 0.1792
Toxoplasma gondii diacylglycerol kinase, putative 0.0035 0.0022 0.0047
Brugia malayi RNA binding protein 0.0064 0.0058 0.0058
Echinococcus multilocularis tumor protein p63 0.0359 0.0418 0.0418
Brugia malayi Thioredoxin reductase 0.0223 0.0252 0.0252
Schistosoma mansoni tyrosine kinase 0.0026 0.0011 0.0011
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0024 0.0009 0.0009
Schistosoma mansoni transcription factor LCR-F1 0.0077 0.0073 0.0073
Mycobacterium ulcerans hypothetical protein 0.0111 0.0115 0.0236
Treponema pallidum NADH oxidase 0.0077 0.0074 0.0069
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0085 0.0083 0.0083
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0013 0.0027
Schistosoma mansoni survival motor neuron protein 0.0051 0.0042 0.0042
Echinococcus granulosus expressed protein 0.0379 0.0443 0.0443
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0057 0.0049 0.0049

Activities

Activity type Activity value Assay description Source Reference
ID50 (functional) = 0.0000063 M Concentration of the compound required for 50% growth inhibition of human breast tumor cells MCF-7 human breast carcinoma cells ChEMBL. 7452700
ID50 (functional) = 0.0000065 M Concentration of the compound required for 50% growth inhibition of the following cell lines human fibro blast cells ChEMBL. 7452700
ID50 (functional) = 0.000011 M Concentration of the compound required for 50% growth inhibition of the following cell lines human bladder carcinoma cells ChEMBL. 7452700
ID50 (functional) = 0.000013 M Concentration of the compound required for 50% growth inhibition of the following cell lines Carcinoma TA-3 cells ChEMBL. 7452700
ID50 (functional) = 0.000019 M Concentration of the compound required for 50% growth inhibition of the following cell lines Leukemia L-1210 cells ChEMBL. 7452700
ID50 (functional) = 0.00002 M Concentration of the compound required for 50% growth inhibition of the following cell lines mouse fibro blasts ChEMBL. 7452700
ID50 (functional) = 0.000027 M Concentration of the compound required for 50% growth inhibition of the following cell lines human burkitt lymphoma cells ChEMBL. 7452700
ID50 (functional) = 0.00003 M Concentration of the compound required for 50% growth inhibition of the following cell lines sarcoma S-180 cells ChEMBL. 7452700
ID50 (functional) = 0.00015 M Concentration of the compound required for 50% growth inhibition of human breast tumor cells SW-613 human breast adenocarcinoma cells ChEMBL. 7452700
ILS (functional) = 14.7 % Antitumor activity against mouse leukemia, L-1210(DBA/2 Ha Mice) % increase in life span at 3.12 mg/kg of dose per day ChEMBL. 7452700
ILS (functional) = 17.4 % Antitumor activity against mouse leukemia, L-1210(DBA/2 Ha Mice) % increase in life span at 3.12 mg/kg of dose per day ChEMBL. 7452700
ILS (functional) = 25.5 % Antitumor activity against slow growing spontaneous mammary tumors in the DBA/2 Ha-DD mouse % increased in life span 3.8 mg/kg/day x 5 melphalan + 50 mg/kg/day compound ChEMBL. 7452700
ILS (functional) = 37.4 % Antitumor activity against mouse leukemia, L-1210(DBA/2 Ha Mice) % increase in life span at 3.12 mg/kg of dose per day ChEMBL. 7452700
ILS (functional) = 60 % Antitumor activity against slow growing spontaneous mammary tumors in the DBA/2 Ha-DD mouse % increased in life span 3.8 mg/kg/day x 5 melphalan + 50 mg/kg/day compound ChEMBL. 7452700
ILS (functional) = 63.1 % Antitumor activity against slow growing spontaneous mammary tumors in the DBA/2 Ha-DD mouse % increased in life span 3.8 mg/kg/day x 5 melphalan + 50 mg/kg/day compound ChEMBL. 7452700
Life span (functional) = 7.3 Antitumor activity against mouse leukemia, L-1210(DBA/2 Ha Mice) mean life span ( days) of the mouse after the dosage at 1.56 mg/kg of dose per day ChEMBL. 7452700
Life span (functional) = 8.6 Antitumor activity against mouse leukemia, L-1210(DBA/2 Ha Mice) mean life span (days) of the mouse after fractionated dosage(dose divided in two halves and administered in two daily injections) at 6.25 mg/kg of dose per day ChEMBL. 7452700
Life span (functional) = 8.8 Antitumor activity against mouse leukemia, L-1210(DBA/2 Ha Mice) mean life span (days) of the mouse after fractionated dosage(dose divided in two halves and administered in two daily injections) at 6.25 mg/kg of dose per day ChEMBL. 7452700
Life span (functional) = 10.3 Antitumor activity against mouse leukemia, L-1210(DBA/2 Ha Mice) mean life span (days) of the mouse after fractionated dosage(dose divided in two halves and administered in two daily injections) at 6.25 mg/kg of dose per day ChEMBL. 7452700
Life span (functional) = 23.6 Antitumor activity against slow growing spontaneous mammary tumors in the DBA/2 Ha-DD mouse mean life span in days at 50 mg/kg give 5 times once in 5 days ChEMBL. 7452700
Life span (functional) = 49.7 Antitumor activity against mouse leukemia, L-1210(DBA/2 Ha Mice) mean life span (days) of the mouse after fractionated dosage(dose divided in two halves and administered in two daily injections) at 6.25 mg/kg of dose per day ChEMBL. 7452700
Life span (functional) = 54.8 Antitumor activity against slow growing spontaneous mammary tumors in the DBA/2 Ha-DD mouse mean life span in days at 50 mg/kg give 5 times once in 5 days ChEMBL. 7452700
Life span (functional) = 63.3 Antitumor activity against slow growing spontaneous mammary tumors in the DBA/2 Ha-DD mouse mean life span in days at 50 mg/kg give 5 times once in 5 days ChEMBL. 7452700
Tumor half growth (functional) = 17 Antitumor activity against slow growing spontaneous mammary tumors in the DBA/2 Ha-DD mouse number of days reacquired fro tumor growth 3.8 mg/kg/day x 5 melphalan once in 5 days ChEMBL. 7452700
Tumor half growth (functional) = 24 Antitumor activity against slow growing spontaneous mammary tumors in the DBA/2 Ha-DD mouse number of days reacquired fro tumor growth 3.8 mg/kg/day x 5 melphalan once in 5 days ChEMBL. 7452700

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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