Detailed information for compound 56680

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 310.339 | Formula: C16H20F2N2O2
  • H donors: 1 H acceptors: 2 LogP: 3.49 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: C[C@@H](NC(=O)[C@@H](C(C)(C)C)C#N)COc1cc(F)ccc1F
  • InChi: 1S/C16H20F2N2O2/c1-10(20-15(21)12(8-19)16(2,3)4)9-22-14-7-11(17)5-6-13(14)18/h5-7,10,12H,9H2,1-4H3,(H,20,21)/t10-,12+/m1/s1
  • InChiKey: QBSPHETXHGBDOW-PWSUYJOCSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Magnaporthe oryzae (strain 70-15 / FGSC 8958) (Rice blast fungus)(Pyricularia oryzae) Scytalone dehydratase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.002 0.0009 0.0028
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0014 0.0126
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0038
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0138 0.0762 0.8442
Echinococcus granulosus biogenic amine 5HT receptor 0.0088 0.0442 0.0481
Onchocerca volvulus 0.0021 0.0013 0.007
Onchocerca volvulus 0.0131 0.0716 0.4014
Trypanosoma cruzi heat shock protein 90, putative 0.0022 0.0021 0.0196
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0088 0.0442 0.0441
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0022 0.0024 0.007
Trypanosoma cruzi Heat shock protein 83, putative 0.0037 0.0119 0.1187
Schistosoma mansoni calcium-activated potassium channel 0.0021 0.0013 0.0013
Trypanosoma brucei heat shock protein, putative 0.0037 0.0119 0.1187
Loa Loa (eye worm) MH2 domain-containing protein 0.0115 0.0618 0.1894
Echinococcus multilocularis lipoxygenase domain containing protein 0.006 0.0265 0.0265
Schistosoma mansoni biogenic amine (5HT) receptor 0.0088 0.0442 0.0481
Loa Loa (eye worm) RGS-3 protein 0.0019 0 0.0001
Echinococcus multilocularis g-protein coupled receptor 0.0088 0.0442 0.0441
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0024 0.0037 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0045 0.0264
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0161 0.0952
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39B 0.0021 0.0013 0.0038
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0041 0.014 0.0433
Echinococcus granulosus rhodopsin orphan GPCR 0.0088 0.0442 0.0481
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0039 0.0129 0.014
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.014 0.0828
Schistosoma mansoni calcium-activated potassium channel 0.0401 0.2444 0.2662
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0 0.0001
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0062 0.0612
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0471 0.2793
Onchocerca volvulus 0.0088 0.0442 0.2474
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0081 0.0398 0.1221
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0054 0.0226 0.2281
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0054 0.0226 0.0226
Echinococcus granulosus sentrin specific protease 7 0.0143 0.0792 0.0863
Brugia malayi PXA domain containing protein 0.0019 0 0.0001
Brugia malayi hypothetical protein 0.0088 0.0442 0.1354
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0013 0.0107
Brugia malayi neuropeptide F receptor 0.0088 0.0442 0.1354
Loa Loa (eye worm) isocitrate dehydrogenase 0.0054 0.0226 0.0693
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0033 0.0089 0.0273
Mycobacterium leprae conserved hypothetical protein 0.0044 0.0161 0.1561
Brugia malayi hypothetical protein 0.0076 0.0365 0.1119
Onchocerca volvulus 0.0088 0.0442 0.2474
Onchocerca volvulus 0.0088 0.0442 0.2474
Leishmania major heat shock protein 83-1 0.0037 0.0119 0.1187
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0041 0.014 0.0429
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0022 0.0024 0.0226
Loa Loa (eye worm) potassium voltage-gated channel subfamily Q member 5 0.0021 0.0013 0.0038
Brugia malayi Cytochrome P450 family protein 0.0022 0.0024 0.0074
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0022 0.0024 0.007
Plasmodium falciparum acyl-CoA synthetase 0.0037 0.012 0.0521
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0062 0.0278 0.0277
Schistosoma mansoni zinc finger protein 0.002 0.0007 0.0007
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0112 0.0122
Schistosoma mansoni neuropeptide receptor 0.0088 0.0442 0.0481
Brugia malayi Cell death protein 3 precursor 0.0026 0.0045 0.0138
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0038
Onchocerca volvulus 0.006 0.0265 0.1486
Schistosoma mansoni carbonic anhydrase-related 0.0033 0.0089 0.0097
Loa Loa (eye worm) hypothetical protein 0.0028 0.0062 0.0191
Brugia malayi PXA domain containing protein 0.0019 0 0.0001
Echinococcus granulosus small conductance calcium activated potassium 0.0477 0.2924 0.3185
Echinococcus multilocularis protein patched 0.0132 0.0722 0.0722
Onchocerca volvulus 0.0021 0.0013 0.007
Echinococcus granulosus geminin 0.0171 0.097 0.1056
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Trypanosoma cruzi metacaspase, putative 0.0026 0.0045 0.0437
Brugia malayi Melatonin receptor type 1A 0.0088 0.0442 0.1354
Echinococcus granulosus 7tm_1 domain containing protein 0.0088 0.0442 0.0481
Onchocerca volvulus 0.0088 0.0442 0.2474
Echinococcus granulosus rhodopsin orphan GPCR 0.0088 0.0442 0.0481
Echinococcus multilocularis nibrin 0.0041 0.014 0.014
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.006 0.0265 0.0264
Schistosoma mansoni biogenic amine receptor 0.0088 0.0442 0.0481
Echinococcus granulosus receptor type guanylyl cyclase 0.0034 0.01 0.0109
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Plasmodium falciparum ataxin-2 like protein, putative 0.0049 0.0195 0.0847
Echinococcus multilocularis g protein coupled receptor 0.0088 0.0442 0.0441
Loa Loa (eye worm) hypothetical protein 0.0032 0.0088 0.0271
Loa Loa (eye worm) hypothetical protein 0.0031 0.0077 0.0235
Loa Loa (eye worm) choline Kinase A 0.0037 0.0116 0.0355
Onchocerca volvulus Huntingtin homolog 0.012 0.065 0.3643
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0024 0.0037 0.004
Trypanosoma cruzi cytochrome P450, putative 0.0022 0.0024 0.0226
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0159 0.0898 0.2812
Toxoplasma gondii cytochrome p450 superfamily protein 0.0022 0.0024 0.0105
Loa Loa (eye worm) cytochrome P450 0.0022 0.0024 0.0074
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0032 0.0088 0.0088
Schistosoma mansoni kinase 0.0047 0.0184 0.02
Echinococcus granulosus g protein coupled receptor 0.0088 0.0442 0.0481
Echinococcus granulosus Protein patched homolog 1 0.0132 0.0722 0.0786
Onchocerca volvulus 0.0088 0.0442 0.2474
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0083 0.0413 0.0413
Brugia malayi metabotropic glutamate receptor type 2 0.0141 0.0781 0.2394
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0032 0.0088 0.0271
Onchocerca volvulus 0.0088 0.0442 0.2474
Trichomonas vaginalis heat shock protein, putative 0.003 0.007 0.0415
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0029 0.0069 0.0068
Echinococcus multilocularis nmda type glutamate receptor 0.0029 0.0069 0.0068
Loa Loa (eye worm) uncoordinated protein 58 0.0021 0.0013 0.0038
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0062 0.0278 0.0852
Loa Loa (eye worm) hypothetical protein 0.0019 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Onchocerca volvulus 0.0088 0.0442 0.2474
Trypanosoma brucei carbonic anhydrase-like protein 0.0143 0.0793 0.805
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0083 0.0413 0.045
Loa Loa (eye worm) hypothetical protein 0.0037 0.0116 0.0355
Trypanosoma cruzi heat shock protein 85, putative 0.0037 0.0119 0.1187
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0027 0.1782
Mycobacterium tuberculosis Conserved protein TB27.3 0.0044 0.0161 0.0498
Loa Loa (eye worm) hypothetical protein 0.0041 0.0143 0.0438
Echinococcus multilocularis tyrosine kinase 0.0034 0.01 0.01
Echinococcus granulosus twik family of potassium channels 0.0021 0.0013 0.0013
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0041 0.014 0.0608
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.0101 0.1004
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0471 0.2793
Echinococcus granulosus neuropeptide receptor A26 0.054 0.3329 0.3626
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0028 0.0164
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0038
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0083 0.0413 0.045
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0088 0.0442 0.0441
Schistosoma mansoni ap endonuclease 0.0019 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Onchocerca volvulus 0.0021 0.0013 0.007
Echinococcus granulosus tm gpcr rhodopsin 0.0088 0.0442 0.0481
Brugia malayi Importin beta-1 subunit 0.0028 0.0062 0.0191
Brugia malayi Pax transcription activation domain interacting protein 0.0041 0.014 0.0429
Schistosoma mansoni tar DNA-binding protein 0.025 0.1481 0.1613
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0014 0.0044
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0132 0.0722 0.2214
Mycobacterium ulcerans heat shock protein 90 0.003 0.007 0.0214
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0054 0.0226 0.0246
Brugia malayi hypothetical protein 0.0088 0.0442 0.1354
Trichomonas vaginalis STE family protein kinase 0.0173 0.0984 0.5843
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0076 0.0365 0.3695
Echinococcus multilocularis isocitrate dehydrogenase 0.0054 0.0226 0.0226
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0088 0.0442 0.0481
Loa Loa (eye worm) steroid hormone receptor 0.0032 0.0088 0.0271
Echinococcus multilocularis thymidylate synthase 0.0159 0.0898 0.0898
Toxoplasma gondii glyoxalase family protein 0.0044 0.0161 0.0698
Onchocerca volvulus Protein ultraspiracle homolog 0.0032 0.0088 0.0495
Brugia malayi hypothetical protein 0.0031 0.0077 0.0235
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0013 0.0107
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0038
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0099 0.0514 0.0559
Loa Loa (eye worm) hypothetical protein 0.0031 0.0077 0.0235
Onchocerca volvulus 0.0032 0.0088 0.0495
Schistosoma mansoni BC026374 protein (S09 family) 0.0131 0.0716 0.078
Echinococcus granulosus nibrin 0.0041 0.014 0.0152
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0088 0.0442 0.0481
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0471 0.2793
Schistosoma mansoni carbonic anhydrase-related 0.0033 0.0089 0.0097
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0159 0.0898 0.9123
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0022 0.0024 0.007
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Loa Loa (eye worm) hypothetical protein 0.0046 0.0172 0.0527
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.014 0.0828
Trypanosoma cruzi metacaspase 5, putative 0.0026 0.0045 0.0437
Onchocerca volvulus 0.0021 0.0013 0.007
Trypanosoma brucei cytochrome P450, putative 0.0022 0.0024 0.0226
Echinococcus granulosus fmrfamide receptor 0.0088 0.0442 0.0481
Loa Loa (eye worm) hypothetical protein 0.0131 0.0716 0.2197
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0022 0.0024 0.007
Schistosoma mansoni transcription factor btf3 0.0034 0.0101 0.0109
Brugia malayi RNA binding protein 0.025 0.1481 0.454
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0014 0.0126
Schistosoma mansoni calcium-activated potassium channel 0.0477 0.2924 0.3185
Trypanosoma brucei heat shock protein 90, putative 0.0037 0.0119 0.1187
Brugia malayi hypothetical protein 0.0088 0.0442 0.1354
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0088 0.0442 0.0481
Brugia malayi RNA recognition motif domain containing protein 0.025 0.1481 0.454
Echinococcus multilocularis glutamate receptor 2 0.0039 0.0129 0.0129
Schistosoma mansoni hypothetical protein 0.0088 0.0442 0.0481
Echinococcus granulosus somatostatin receptor 0.0088 0.0442 0.0481
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0022 0.0024 0.007
Echinococcus granulosus expressed protein 0.0364 0.2202 0.2399
Echinococcus multilocularis dual specificity mitogen activated protein 0.0173 0.0984 0.0984
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0026 0.0045 0.0195
Leishmania major heat shock protein 83-1 0.0037 0.0119 0.1187
Brugia malayi Tachykinin-like peptides receptor 99D 0.0088 0.0442 0.1354
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0099 0.0514 0.0513
Brugia malayi hypothetical protein 0.0088 0.0442 0.1354
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0291 0.2943
Mycobacterium tuberculosis Conserved protein 0.0044 0.0161 0.0498
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0159 0.0898 0.3902
Echinococcus multilocularis heat shock protein 90 0.0037 0.0119 0.0118
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0062 0.0278 0.0277
Echinococcus multilocularis tar DNA binding protein 0.025 0.1481 0.148
Plasmodium falciparum metacaspase-like protein 0.0026 0.0045 0.0195
Loa Loa (eye worm) endoplasmin 0.0037 0.0119 0.0364
Brugia malayi Carboxylesterase family protein 0.0529 0.3261 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0045 0.0138
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0196 0.1135 0.348
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0045 0.0195
Echinococcus multilocularis fmrfamide receptor 0.0088 0.0442 0.0441
Trypanosoma cruzi lactoylglutathione lyase-like protein, putative 0.0044 0.0161 0.1615
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0032 0.0088 0.0271
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0143 0.0792 0.4304
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0088 0.0442 0.0481
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.002 0.0009 0.0028
Leishmania major heat shock protein 83-1 0.0037 0.0119 0.1187
Leishmania major ion transport protein-like protein 0.0021 0.0013 0.0107
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0022 0.0024 0.007
Echinococcus granulosus TWiK family of potassium channels protein 7 0.0021 0.0013 0.0013
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0028 0.0164
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 12 0.0021 0.0013 0.0038
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0022 0.0024 0.007
Loa Loa (eye worm) hypothetical protein 0.0083 0.0413 0.1268
Brugia malayi Carboxylesterase family protein 0.0131 0.0716 0.2197
Onchocerca volvulus 0.0021 0.0013 0.007
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0088 0.0442 0.0441
Brugia malayi CHE-14 protein 0.0132 0.0722 0.2214
Schistosoma mansoni twik family of potassium channels-related 0.0021 0.0013 0.0013
Schistosoma mansoni hypothetical protein 0.0088 0.0442 0.0481
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.005 0.0201 0.2019
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0041 0.014 1
Trypanosoma cruzi heat shock protein 90, putative 0.0037 0.0119 0.1187
Brugia malayi hypothetical protein 0.012 0.065 0.1994
Entamoeba histolytica hypothetical protein 0.0031 0.0077 0.0414
Brugia malayi Carboxylesterase family protein 0.0529 0.3261 1
Brugia malayi ecdysteroid receptor 0.0032 0.0088 0.0271
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.0088 0.0271
Echinococcus multilocularis heat shock protein 90 0.003 0.007 0.007
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0041 0.014 0.1324
Onchocerca volvulus 0.0021 0.0013 0.007
Trypanosoma cruzi ion transport protein, putative 0.0021 0.0013 0.0107
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0014 0.0063
Schistosoma mansoni hypothetical protein 0.0127 0.0692 0.0753
Schistosoma mansoni choline/ethanolamine kinase 0.0037 0.0116 0.0126
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0107 0.0329
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0014 0.0014
Leishmania major heat shock protein 83-1 0.0037 0.0119 0.1187
Schistosoma mansoni chromosome transmission fidelity factor 0.0041 0.014 0.0152
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0038
Echinococcus granulosus neuropeptide Y receptor 0.0088 0.0442 0.0481
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0143 0.0793 0.2431
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0032 0.0088 0.0495
Echinococcus granulosus allatostatin A receptor 0.0088 0.0442 0.0481
Schistosoma mansoni hypothetical protein 0.0477 0.2924 0.3185
Giardia lamblia Kinase, PLK 0.0092 0.0471 0.2786
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0014 0.0044
Leishmania major heat shock protein 83-1 0.0037 0.0119 0.1187
Schistosoma mansoni tyrosine kinase 0.0034 0.01 0.0109
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0032 0.0088 0.0096
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0088 0.0442 0.1354
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0022 0.0024 0.007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0291 0.2943
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 28 0.0021 0.0013 0.0038
Trichomonas vaginalis choline/ethanolamine kinase, putative 0.0037 0.0116 0.0684
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0033 0.0089 0.0273
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0307 0.184 1
Schistosoma mansoni acetylcholinesterase 0.0131 0.0716 0.078
Brugia malayi TAR-binding protein 0.025 0.1481 0.454
Loa Loa (eye worm) hypothetical protein 0.0019 0 0.0001
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 17 0.0021 0.0013 0.0038
Leishmania major cathepsin L-like protease 0.0064 0.0291 0.2943
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0088 0.0088
Schistosoma mansoni hypothetical protein 0.0083 0.0413 0.045
Schistosoma mansoni hypothetical protein 0.0033 0.0089 0.0097
Trypanosoma cruzi choline kinase 0.0037 0.0116 0.1156
Trypanosoma brucei calcium-activated potassium channel, putative 0.0021 0.0013 0.0107
Leishmania major heat shock protein 83-1 0.0037 0.0119 0.1187
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0032 0.0088 0.0096
Echinococcus granulosus tm gpcr rhodopsin 0.0088 0.0442 0.0481
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.0024 0.0074
Echinococcus granulosus peptide allatostatin:somatostatin 0.0088 0.0442 0.0481
Plasmodium vivax glyoxalase I, putative 0.0044 0.0161 0.0698
Echinococcus multilocularis rhodopsin orphan GPCR 0.0088 0.0442 0.0441
Echinococcus multilocularis rhodopsin orphan GPCR 0.0088 0.0442 0.0441
Schistosoma mansoni hypothetical protein 0.0127 0.0692 0.0753
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0312 0.1871 0.2038
Schistosoma mansoni neuropeptide receptor 0.0088 0.0442 0.0481
Brugia malayi Choline/ethanolamine kinase family protein 0.0379 0.2301 0.7057
Echinococcus multilocularis geminin 0.0171 0.097 0.097
Trypanosoma brucei choline kinase 0.0037 0.0116 0.1156
Echinococcus granulosus thymidylate synthase 0.0159 0.0898 0.0978
Plasmodium falciparum importin beta, putative 0.0028 0.0062 0.027
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0088 0.0442 0.0481
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0088 0.0442 0.0481
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.014 0.1403
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0023 0.0026 0.0026
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0088 0.0442 0.1354
Echinococcus granulosus biogenic amine 5HT receptor 0.0088 0.0442 0.0481
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0101 0.0595
Loa Loa (eye worm) large conductance calcium-activated potassium channel alpha subunit ai 0.0021 0.0013 0.0038
Plasmodium vivax ethanolamine kinase, putative 0.0037 0.0116 0.0502
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0045 0.0264
Echinococcus granulosus tyrosine kinase 0.0034 0.01 0.0109
Loa Loa (eye worm) latrophilin receptor protein 2 0.0062 0.0278 0.0852
Brugia malayi Doublecortin family protein 0.006 0.0265 0.0813
Loa Loa (eye worm) hypothetical protein 0.0131 0.0716 0.2197
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.0088 0.0271
Toxoplasma gondii phosphotransferase enzyme family protein 0.0037 0.0116 0.0502
Onchocerca volvulus Huntingtin homolog 0.012 0.065 0.3643
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0083 0.0413 0.1268
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0291 0.2943
Brugia malayi beta-NAC-like protein 0.0034 0.0101 0.0309
Brugia malayi hypothetical protein 0.0049 0.0195 0.0598
Loa Loa (eye worm) hypothetical protein 0.0026 0.0045 0.0138
Brugia malayi Dopamine receptor protein 1 0.0088 0.0442 0.1354
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0088 0.0442 0.0481
Schistosoma mansoni amine GPCR 0.0088 0.0442 0.0481
Trichomonas vaginalis STE family protein kinase 0.0173 0.0984 0.5843
Giardia lamblia Hypothetical protein 0.0021 0.0013 0.0062
Brugia malayi T-complex protein 1, beta subunit 0.0024 0.0037 0.0113
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0291 0.2943
Brugia malayi topoisomerase 0.0041 0.014 0.0429
Loa Loa (eye worm) carboxylesterase 0.0529 0.3261 1
Echinococcus granulosus Niemann Pick C1 protein 0.0307 0.184 0.2005
Echinococcus multilocularis acetylcholinesterase 0.0529 0.3261 0.3261
Schistosoma mansoni hypothetical protein 0.0171 0.097 0.1056
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0028 0.0164
Brugia malayi G-protein coupled receptor 0.0088 0.0442 0.1354
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0176 0.1046
Brugia malayi hypothetical protein 0.0088 0.0442 0.1354
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Brugia malayi hypothetical protein 0.0131 0.0716 0.2197
Echinococcus granulosus g-protein coupled receptor 0.0088 0.0442 0.0481
Loa Loa (eye worm) hypothetical protein 0.012 0.065 0.1994
Onchocerca volvulus 0.0021 0.0013 0.007
Toxoplasma gondii heat shock protein HSP90 0.0037 0.0119 0.0516
Trypanosoma cruzi PAB1-binding protein , putative 0.0049 0.0195 0.1964
Onchocerca volvulus 0.005 0.0201 0.1124
Echinococcus multilocularis Two pore potassium channel protein sup 9 0.0021 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0038
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0254 0.1503 0.4609
Schistosoma mansoni hypothetical protein 0.0303 0.1813 0.1975
Echinococcus granulosus tachykinin peptides receptor 99D 0.0088 0.0442 0.0481
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0022 0.0024 0.007
Brugia malayi hypothetical protein 0.0088 0.0442 0.1354
Plasmodium falciparum potassium channel 0.0021 0.0013 0.0054
Brugia malayi Choline/ethanolamine kinase family protein 0.0037 0.0116 0.0355
Echinococcus granulosus lipoxygenase domain containing protein 0.006 0.0265 0.0288
Mycobacterium ulcerans hypothetical protein 0.0044 0.0161 0.0498
Entamoeba histolytica hypothetical protein 0.0023 0.0028 0.015
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0032 0.0088 0.0271
Onchocerca volvulus Serine\/threonine kinase homolog 0.0092 0.0471 0.2637
Brugia malayi hypothetical protein 0.0088 0.0442 0.1354
Mycobacterium ulcerans fatty-acid-CoA ligase 0.005 0.0201 0.0623
Schistosoma mansoni hypothetical protein 0.0127 0.0692 0.0753
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0038
Schistosoma mansoni hypothetical protein 0.0021 0.0013 0.0013
Echinococcus multilocularis heat shock protein 0.0037 0.0119 0.0118
Schistosoma mansoni RAR-like nuclear receptor 0.0032 0.0088 0.0096
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0032 0.0088 0.0271
Echinococcus granulosus carbonic anhydrase II 0.0143 0.0793 0.0863
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0021 0.0016 0.0044
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0038
Brugia malayi Niemann-Pick C1 protein precursor 0.0307 0.184 0.5644
Echinococcus multilocularis rhodopsin orphan GPCR 0.0088 0.0442 0.0441
Loa Loa (eye worm) hypothetical protein 0.0031 0.0077 0.0235
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0027 0.0116
Loa Loa (eye worm) hypothetical protein 0.0037 0.012 0.0368
Loa Loa (eye worm) hypothetical protein 0.0041 0.014 0.0429
Schistosoma mansoni coup transcription factor 0.0032 0.0088 0.0096
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0 0.0001
Brugia malayi hypothetical protein 0.0088 0.0442 0.1354
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.003 0.007 0.0527
Loa Loa (eye worm) hypothetical protein 0.0037 0.012 0.0368
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0038
Schistosoma mansoni tar DNA-binding protein 0.025 0.1481 0.1613
Brugia malayi AMP-binding enzyme family protein 0.005 0.0201 0.0615
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0088 0.0442 0.0481
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0291 0.2943
Echinococcus multilocularis RUN 0.006 0.0265 0.0265
Mycobacterium ulcerans glyoxalase GloA 0.0044 0.0161 0.0498
Leishmania major extracellular receptor, putative 0.0031 0.0077 0.0758
Leishmania major heat shock protein 83-1 0.0037 0.0119 0.1187
Echinococcus multilocularis expressed protein 0.0364 0.2202 0.2202
Leishmania major choline/ethanolamine kinase, putative 0.0037 0.0116 0.1156
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0088 0.0442 0.0481
Trypanosoma cruzi metacaspase, putative 0.0026 0.0045 0.0437
Schistosoma mansoni biogenic amine (5HT) receptor 0.0088 0.0442 0.0481
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0471 0.2793
Echinococcus multilocularis Polycystic kidney disease protein 0.006 0.0265 0.0265
Entamoeba histolytica choline/ethanolamine kinase, putative 0.0037 0.0116 0.0626
Leishmania major cytochrome p450-like protein 0.0022 0.0024 0.0226
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 45 0.0021 0.0013 0.0038
Echinococcus multilocularis neuroligin 0.0131 0.0716 0.0716
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0054 0.0226 0.0982
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0131 0.0716 0.0716
Schistosoma mansoni hypothetical protein 0.0171 0.097 0.1056
Schistosoma mansoni steroid hormone receptor ad4bp 0.0032 0.0088 0.0096
Echinococcus granulosus beta-adrenergic receptor kinase 0.002 0.0009 0.001
Trichomonas vaginalis heat shock protein, putative 0.0037 0.0119 0.0702
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0032 0.0088 0.0096
Schistosoma mansoni lipoxygenase 0.006 0.0265 0.0288
Echinococcus multilocularis carboxylesterase 5A 0.0529 0.3261 0.3261
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0028 0.0264
Echinococcus multilocularis glutamate receptor 2 0.0031 0.0077 0.0076
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0027 0.025
Loa Loa (eye worm) hypothetical protein 0.0034 0.01 0.0307
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0092 0.0471 0.0512
Toxoplasma gondii ATPase, AAA family protein 0.0041 0.014 0.0608
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0022 0.0024 0.007
Echinococcus multilocularis carbonic anhydrase 0.0033 0.0089 0.0089
Leishmania major heat shock protein 83-1 0.0037 0.0119 0.1187
Brugia malayi G protein-coupled receptor F59B2.13 0.0088 0.0442 0.1354
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0022 0.0024 0.007
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Trypanosoma brucei transcription factor BTF3, putative 0.0034 0.0101 0.1004
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.0024 0.0074
Echinococcus granulosus cytochrome P450 2K1 0.0022 0.0024 0.0026
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Onchocerca volvulus 0.0088 0.0442 0.2474
Schistosoma mansoni gynecophoral canal protein 0.0044 0.0161 0.0175
Schistosoma mansoni amine GPCR 0.0088 0.0442 0.0481
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0002 0.0002
Leishmania major heat shock protein 83-1 0.0037 0.0119 0.1187
Trypanosoma brucei metacaspase 0.0026 0.0045 0.0437
Schistosoma mansoni hypothetical protein 0.0147 0.0819 0.0892
Schistosoma mansoni hypothetical protein 0.0088 0.0442 0.0481
Trypanosoma cruzi heat shock protein 90, putative 0.003 0.007 0.0695
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0041 0.014 0.1403
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0273
Toxoplasma gondii glyoxalase I, putative 0.0044 0.0161 0.0698
Leishmania major heat shock protein 83-1 0.0037 0.0119 0.1187
Brugia malayi Cytochrome P450 family protein 0.0022 0.0024 0.0074
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0143 0.0793 0.2431
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0054 0.0226 0.2281
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0088 0.0442 0.0481
Entamoeba histolytica hypothetical protein 0.0041 0.014 0.0758
Loa Loa (eye worm) thymidylate synthase 0.0159 0.0898 0.2754
Giardia lamblia Ethanolamine kinase, putative 0.0037 0.0116 0.0675
Trypanosoma cruzi metacaspase 5, putative 0.0026 0.0045 0.0437
Entamoeba histolytica hypothetical protein 0.0034 0.0101 0.0545
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0173 0.0984 0.3018
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0045 0.0264
Loa Loa (eye worm) ICD-1 protein 0.0034 0.0101 0.0309
Loa Loa (eye worm) hypothetical protein 0.0043 0.0155 0.0476
Echinococcus granulosus g protein coupled receptor 0.0088 0.0442 0.0481
Schistosoma mansoni hypothetical protein 0.0022 0.0024 0.0026
Echinococcus granulosus hypothetical protein 0.0088 0.0442 0.0481
Echinococcus granulosus neuropeptide Y receptor 0.0088 0.0442 0.0481
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0201 0.0623
Echinococcus granulosus rhodopsin orphan GPCR 0.0088 0.0442 0.0481
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0045 0.0264
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.0088 0.0271
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0096 0.0494 0.0493
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0032 0.0088 0.0271
Onchocerca volvulus 0.0131 0.0716 0.4014
Brugia malayi nuclear hormone receptor 0.0032 0.0088 0.0271
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0159 0.0898 0.9123
Loa Loa (eye worm) hypothetical protein 0.0062 0.0278 0.0852
Plasmodium falciparum LCCL domain-containing protein 0.006 0.0265 0.1152
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0088 0.0442 0.0481
Leishmania major cytochrome p450-like protein 0.0022 0.0024 0.0226
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0131 0.0716 0.4253
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0026 0.0045 0.0195
Brugia malayi latrophilin 2 splice variant baaae 0.0134 0.0738 0.2264
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0041 0.014 0.0828
Schistosoma mansoni hypothetical protein 0.0134 0.0738 0.0804
Brugia malayi hypothetical protein 0.0041 0.014 0.0429
Echinococcus multilocularis rhodopsin orphan GPCR 0.0088 0.0442 0.0441
Schistosoma mansoni twik family of potassium channels-related 0.0021 0.0013 0.0013
Plasmodium falciparum choline kinase 0.0379 0.2301 1
Onchocerca volvulus 0.0034 0.01 0.0561
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0088 0.0442 0.0481
Brugia malayi serine/threonine-protein kinase plk-2 0.0092 0.0471 0.1444
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0088 0.0442 0.0441
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0273
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0131 0.0716 0.078
Echinococcus granulosus Two pore potassium channel protein sup 9 0.0021 0.0013 0.0013
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0138 0.0762 0.2385
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0032 0.0088 0.0096
Brugia malayi putative neuropeptide receptor NPR1 0.0088 0.0442 0.1354
Onchocerca volvulus Cell death protein 3 homolog 0.0026 0.0045 0.0252
Trypanosoma cruzi metacaspase, putative 0.0026 0.0045 0.0437
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0038
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0062 0.0278 0.0302
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0088 0.0442 0.2474
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0038
Loa Loa (eye worm) hypothetical protein 0.0041 0.014 0.0429
Brugia malayi Cytochrome P450 family protein 0.0022 0.0024 0.0074
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0303 0.1813 0.5561
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0038
Schistosoma mansoni caspase-7 (C14 family) 0.0026 0.0045 0.0049
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0021 0.0013 0.0107
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0291 0.2943
Plasmodium vivax importin-beta 2, putative 0.0028 0.0062 0.027
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0107 0.0329
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0099 0.0514 0.0513
Trypanosoma brucei heat shock protein, putative 0.0037 0.0119 0.1187
Brugia malayi G protein-coupled receptor 0.0088 0.0442 0.1354
Schistosoma mansoni ran 0.0021 0.0014 0.0015
Echinococcus multilocularis G-protein coupled receptor, putative 0.0088 0.0442 0.0441
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0088 0.0442 0.0481
Echinococcus multilocularis potassium channel subfamily K 8 0.0021 0.0013 0.0012
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0088 0.0442 0.1354
Echinococcus granulosus caspase 8 0.0026 0.0045 0.0049
Mycobacterium ulcerans hypothetical protein 0.0044 0.0161 0.0498
Echinococcus multilocularis choline:ethanolamine kinase 0.0379 0.2301 0.2301
Mycobacterium ulcerans thymidylate synthase 0.0159 0.0898 0.2812
Loa Loa (eye worm) hypothetical protein 0.0019 0 0.0001
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0088 0.0442 0.1354
Echinococcus multilocularis snurportin 1 0.0303 0.1813 0.1813
Brugia malayi neuropeptide F receptor 0.0088 0.0442 0.1354
Entamoeba histolytica acyl-CoA synthetase, putative 0.005 0.0201 0.1088
Trypanosoma cruzi lactoylglutathione lyase-like protein, putative 0.0044 0.0161 0.1615
Schistosoma mansoni hypothetical protein 0.0021 0.0014 0.0015
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0046 0.0172 0.0527
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0002 0.001
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0023 0.0026 0.0028
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0088 0.0442 0.0481
Echinococcus multilocularis acetylcholinesterase 0.0529 0.3261 0.3261
Loa Loa (eye worm) hypothetical protein 0.0037 0.012 0.0368
Schistosoma mansoni rab6-interacting 0.006 0.0265 0.0288
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0088 0.0096
Brugia malayi hypothetical protein 0.0021 0.0013 0.0038
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0131 0.0716 0.078
Mycobacterium ulcerans transmembrane cation transporter 0.0021 0.0013 0.0033
Entamoeba histolytica Ran family GTPase 0.0021 0.0014 0.0076
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0131 0.0716 0.078
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0026 0.0045 0.0138
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0201 0.0623
Echinococcus granulosus rhodopsin orphan GPCR 0.0088 0.0442 0.0481
Leishmania major glyoxalase I,trypanothione-dependent glyoxalase I 0.0044 0.0161 0.1615
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0039 0.0129 0.0129
Mycobacterium ulcerans hypothetical protein 0.005 0.0201 0.0623
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0062 0.0062
Loa Loa (eye worm) TYRA-2 protein 0.0088 0.0442 0.1354
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0131 0.0716 0.078
Mycobacterium ulcerans carboxylesterase, LipT 0.0518 0.3188 1
Leishmania major T-complex protein 1, beta subunit, putative 0.0024 0.0037 0.0353
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0059 0.0256 0.2581
Onchocerca volvulus Poor gastrulation protein homolog 0.0046 0.0172 0.0962
Trypanosoma brucei polo-like protein kinase 0.0092 0.0471 0.4772
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0009 0.001
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0024 0.0037 0.0353
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0033 0.0089 0.0273
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0107 0.0329
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0088 0.0442 0.0441
Trypanosoma brucei metacaspase 5, putative 0.0026 0.0045 0.0437
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0088 0.0442 0.0441
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Echinococcus multilocularis replication factor c subunit 1 0.0041 0.014 0.014
Plasmodium falciparum metacaspase 1 0.0026 0.0045 0.0195
Plasmodium vivax replication factor C subunit 1, putative 0.0041 0.014 0.0608
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.0088 0.0271
Brugia malayi heat shock protein 90 0.0037 0.0119 0.0364
Mycobacterium tuberculosis Hypothetical protein 0.0076 0.0365 0.1139
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0038
Onchocerca volvulus 0.0031 0.0077 0.0429
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.0088 0.0271
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0045 0.0264
Brugia malayi Serotonin receptor 0.0088 0.0442 0.1354
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0088 0.0442 0.1354
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0076 0.0367 0.1126
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.005 0.0201 0.0623
Plasmodium vivax acyl-CoA synthetase, putative 0.0037 0.012 0.0521
Brugia malayi Receptor family ligand binding region containing protein 0.0034 0.01 0.0307
Brugia malayi larval opioid receptor 0.0088 0.0442 0.1354
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.0101 0.1004
Trypanosoma brucei metacaspase MCA3 0.0026 0.0045 0.0437
Leishmania major heat shock protein 83-1 0.0037 0.0119 0.1187
Echinococcus granulosus ethanolamine kinase 2 0.0037 0.0116 0.0126
Loa Loa (eye worm) carboxylesterase 0.0131 0.0716 0.2197
Trypanosoma cruzi major cysteine proteinase, putative 0.005 0.0203 0.205
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0022 0.0024 0.0226
Schistosoma mansoni opsin-like receptor 0.0088 0.0442 0.0481
Giardia lamblia Heat shock protein HSP 90-alpha 0.003 0.007 0.0406
Onchocerca volvulus 0.0088 0.0442 0.2474
Loa Loa (eye worm) hypothetical protein 0.006 0.0265 0.0813
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0022 0.0024 0.007
Loa Loa (eye worm) hypothetical protein 0.0131 0.0716 0.2197
Loa Loa (eye worm) hypothetical protein 0.006 0.0265 0.0813
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.005 0.0201 0.0623
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0041 0.014 0.1403
Onchocerca volvulus 0.0088 0.0442 0.2474
Trichomonas vaginalis STE family protein kinase 0.0173 0.0984 0.5843
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.003 0.007 0.0076
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0291 0.2943
Echinococcus granulosus Polycystic kidney disease protein 0.006 0.0265 0.0288
Echinococcus multilocularis expressed conserved protein 0.013 0.0713 0.0712
Loa Loa (eye worm) hypothetical protein 0.0019 0 0.0001
Brugia malayi Guanylyl cyclase protein 23 0.0034 0.01 0.0307
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0054 0.0226 0.0246
Echinococcus multilocularis protein dispatched 1 0.015 0.0841 0.084
Brugia malayi Receptor family ligand binding region containing protein 0.0076 0.0367 0.1126
Echinococcus granulosus para nitrobenzyl esterase 0.0131 0.0716 0.078
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Echinococcus multilocularis carbonic anhydrase 0.0033 0.0089 0.0089
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0014 0.0126
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0024 0.0037 0.0216
Schistosoma mansoni carbonic anhydrase-related 0.0033 0.0089 0.0097
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.0021 0.0013 0.0038
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0022 0.0024 0.007
Schistosoma mansoni ap endonuclease 0.0019 0.0002 0.0002
Echinococcus multilocularis serotonin receptor 0.0088 0.0442 0.0441
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0022 0.0024 0.007
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0088 0.0442 0.0481
Schistosoma mansoni protein kinase 0.0034 0.01 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0161 0.0952
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0173 0.0984 1
Echinococcus multilocularis para nitrobenzyl esterase 0.0131 0.0716 0.0716
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0022 0.0024 0.007
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0022 0.0024 0.007
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0088 0.0442 0.0481
Leishmania major heat shock protein 83-1 0.0037 0.0119 0.1187
Echinococcus multilocularis neuropeptide Y receptor 0.0088 0.0442 0.0441
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0143 0.0793 0.0863
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.014 0.0828
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0026 0.0045 0.0195
Toxoplasma gondii ion channel protein 0.0021 0.0013 0.0054
Onchocerca volvulus 0.0088 0.0442 0.2474
Brugia malayi Isocitrate dehydrogenase 0.0054 0.0226 0.0693
Brugia malayi follicle stimulating hormone receptor 0.0088 0.0442 0.1354
Trichomonas vaginalis replication factor C large subunit, putative 0.0041 0.014 0.0828
Loa Loa (eye worm) choline/ethanolamine kinase 0.0379 0.2301 0.7057
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0032 0.0088 0.0096
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0088 0.0442 0.1354
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0045 0.0264
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0021 0.0013 0.0107
Brugia malayi hypothetical protein 0.0019 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0211 0.1232 0.3777
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.019 0.1093 0.3352
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0291 0.2943
Echinococcus multilocularis thyroid hormone receptor alpha 0.0032 0.0088 0.0088
Echinococcus multilocularis rhodopsin orphan GPCR 0.0088 0.0442 0.0441
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0291 0.2943
Onchocerca volvulus 0.0088 0.0442 0.2474
Plasmodium falciparum glyoxalase I 0.0044 0.0161 0.0698
Plasmodium falciparum glyoxalase I 0.0044 0.0161 0.0698
Schistosoma mansoni 4-hydroxyphenylpyruvate dioxygenase 0.0044 0.0161 0.0175
Schistosoma mansoni transcription factor LCR-F1 0.0147 0.0819 0.0892
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0032 0.0088 0.0271
Loa Loa (eye worm) apoptosis regulator protein 0.0083 0.0413 0.1268
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Trypanosoma cruzi calcium-activated potassium channel, putative 0.0021 0.0013 0.0107
Toxoplasma gondii isocitrate dehydrogenase 0.0054 0.0226 0.0982
Entamoeba histolytica hypothetical protein 0.0147 0.0819 0.4448
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0022 0.0024 0.007
Plasmodium falciparum basic transcription factor 3b, putative 0.0034 0.0101 0.0437
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.014 0.1403
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0031 0.0077 0.0076
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 13 0.0021 0.0013 0.0038
Schistosoma mansoni calcium-activated potassium channel 0.0021 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0161 0.0911 0.2794
Mycobacterium tuberculosis Cadmium inducible protein CadI 0.0044 0.0161 0.0498
Echinococcus granulosus expressed conserved protein 0.0288 0.1722 0.1875
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0026 0.0045 0.0049
Echinococcus multilocularis L aminoadipate semialdehyde 0.0081 0.0398 0.0398
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0054 0.0226 0.0703
Brugia malayi hypothetical protein 0.0088 0.0442 0.1354
Echinococcus multilocularis sterol regulatory element binding protein 0.0132 0.0722 0.0722
Echinococcus granulosus FTZ F1 alpha 0.0032 0.0088 0.0096
Echinococcus granulosus GPCR family 3 C terminal 0.0046 0.0172 0.0187
Schistosoma mansoni amine GPCR 0.0088 0.0442 0.0481
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Brugia malayi Calcitonin receptor-like protein seb-1 0.0196 0.1135 0.348
Echinococcus granulosus neuroligin 0.0131 0.0716 0.078
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0022 0.0024 0.007
Loa Loa (eye worm) hypothetical protein 0.0131 0.0716 0.2197
Echinococcus multilocularis nmda type glutamate receptor 0.0031 0.0077 0.0076
Echinococcus multilocularis GPCR, family 3, C terminal 0.0046 0.0172 0.0171
Mycobacterium tuberculosis Conserved hypothetical protein 0.0044 0.0161 0.0498
Onchocerca volvulus Putative choline\/ethanolamine kinase 0.0037 0.0116 0.0648
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0022 0.0024 0.007
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0054 0.0226 0.2281
Echinococcus multilocularis endoplasmin 0.003 0.007 0.007
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.1684 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0088 0.0096
Loa Loa (eye worm) hypothetical protein 0.0019 0 0.0001
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.003 0.007 0.0214
Echinococcus granulosus metabotropic glutamate receptor 2 0.0239 0.1408 0.1533
Echinococcus multilocularis caspase 8 0.0026 0.0045 0.0045
Echinococcus granulosus calcium activated potassium channel variant 0.0021 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0038
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Schistosoma mansoni twik family of potassium channels-related 0.0021 0.0013 0.0013
Echinococcus multilocularis 0.0022 0.0024 0.0024
Trypanosoma cruzi FHA domain containing protein, putative 0.0041 0.014 0.1403
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0143 0.0793 0.2431
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0027 0.0116
Loa Loa (eye worm) hypothetical protein 0.0131 0.0716 0.2197
Trypanosoma cruzi ion transport protein, putative 0.0021 0.0013 0.0107
Brugia malayi Latrophilin receptor protein 2 0.0062 0.0278 0.0852
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0022 0.0024 0.0226
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0088 0.0442 0.0441
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0038
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.005 0.0201 0.0623
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0021 0.0013 0.0072
Echinococcus granulosus snurportin 1 0.0303 0.1813 0.1975
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0039 0.0129 0.014
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0002 0.0009
Schistosoma mansoni hypothetical protein 0.0062 0.0278 0.0302
Brugia malayi nuclear receptor NHR-88 0.0032 0.0088 0.0271
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Giardia lamblia Heat shock protein HSP 90-alpha 0.0037 0.0119 0.0693
Loa Loa (eye worm) choline/ethanolamine kinase 0.0037 0.0116 0.0355
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 39A 0.0021 0.0013 0.0038
Giardia lamblia TCP-1 chaperonin subunit beta 0.0024 0.0037 0.0206
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0038
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 5 0.0021 0.0013 0.0038
Echinococcus multilocularis small conductance calcium activated potassium 0.0477 0.2924 0.2924
Plasmodium falciparum replication factor C subunit 1, putative 0.0041 0.014 0.0608
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0024 0.0037 0.0198
Trypanosoma brucei heat shock protein, putative 0.0037 0.0119 0.1187
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.1684 1
Loa Loa (eye worm) acetylcholinesterase 1 0.0529 0.3261 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.0034 0.01 0.0307
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0002 0.0009
Onchocerca volvulus 0.0131 0.0716 0.4014
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0002 0.0006
Echinococcus granulosus glutamate receptor 2 0.0039 0.0129 0.014
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0201 0.0623
Echinococcus granulosus zinc finger protein 0.002 0.0007 0.0007
Brugia malayi hypothetical protein 0.0032 0.0084 0.0257
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0038
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0083 0.0413 0.045
Schistosoma mansoni adenoreceptor 0.0088 0.0442 0.0481
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0021 0.0013 0.0072
Echinococcus granulosus potassium channel subfamily K 8 0.0021 0.0013 0.0013
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 24 0.0021 0.0013 0.0038
Echinococcus granulosus sex peptide receptor 0.0088 0.0442 0.0481
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0014 0.0042
Echinococcus multilocularis GPCR, family 2 0.0062 0.0278 0.0277
Schistosoma mansoni twik family of potassium channels-related 0.0021 0.0013 0.0013
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0176 0.1046
Mycobacterium tuberculosis Carboxylesterase LipT 0.0518 0.3188 1
Brugia malayi hypothetical protein 0.0088 0.0442 0.1354
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0032 0.0088 0.0271
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.1684 1
Schistosoma mansoni protein kinase 0.0173 0.0984 0.1072
Brugia malayi Metabotropic glutamate receptor precursor. 0.0285 0.1698 0.5208
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0022 0.0024 0.007
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0054 0.0226 0.0226
Echinococcus granulosus 7TM GPCR rhodopsin 0.0088 0.0442 0.0481
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0159 0.0898 0.3902
Echinococcus multilocularis expressed conserved protein 0.0288 0.1722 0.1721
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Plasmodium falciparum ataxin-2 like protein, putative 0.0049 0.0195 0.0847
Loa Loa (eye worm) heat shock protein 90 0.0037 0.0119 0.0364
Echinococcus multilocularis neuropeptide FF receptor 2 0.0088 0.0442 0.0441
Brugia malayi DKFZp564C0469 protein 0.0041 0.014 0.0429
Plasmodium vivax choline kinase, putative 0.0379 0.2301 1
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Echinococcus granulosus neuropeptide s receptor 0.054 0.3329 0.3626
Schistosoma mansoni heat shock protein 0.0037 0.0119 0.0129
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0027 0.0027
Schistosoma mansoni hypothetical protein 0.0062 0.0278 0.0302
Echinococcus multilocularis neuropeptide s receptor 0.054 0.3329 0.3329
Schistosoma mansoni importin beta-1 0.0028 0.0062 0.0067
Onchocerca volvulus Lactoylglutathione lyase homolog 0.0044 0.0161 0.09
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Schistosoma mansoni choline/ethanolamine kinase 0.0037 0.0116 0.0126
Echinococcus granulosus neuropeptide receptor 0.0088 0.0442 0.0481
Loa Loa (eye worm) hypothetical protein 0.0033 0.0089 0.0273
Trypanosoma brucei heat shock protein, putative 0.0037 0.0119 0.1187
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0038
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0002 0.001
Schistosoma mansoni alpha-1 adrenergic receptor 0.0088 0.0442 0.0481
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0282 0.1684 0.9151
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0045 0.0264
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0143 0.0793 0.805
Onchocerca volvulus Putative protein 0.0298 0.1785 1
Entamoeba histolytica choline/ethanolamine kinase, putative 0.0037 0.0116 0.0626
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0101 0.0595
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0062 0.027
Plasmodium falciparum potassium channel 0.0021 0.0013 0.0054
Echinococcus granulosus L aminoadipate semialdehyde 0.0081 0.0398 0.0433
Schistosoma mansoni patched 1 0.0132 0.0722 0.0786
Leishmania major choline kinase 0.0037 0.0116 0.1156
Echinococcus granulosus glutamate receptor 2 0.0031 0.0077 0.0083
Schistosoma mansoni twik family of potassium channels-related 0.0021 0.0013 0.0013
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0014 0.0015
Echinococcus granulosus acetylcholinesterase 0.0529 0.3261 0.3552
Loa Loa (eye worm) hypothetical protein 0.005 0.0201 0.0615
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0045 0.0264
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0101 0.0595
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0032 0.0088 0.0088
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0022 0.0024 0.007
Leishmania major hypothetical protein, conserved 0.0021 0.0013 0.0107
Loa Loa (eye worm) hypothetical protein 0.0071 0.0336 0.1029
Schistosoma mansoni tar DNA-binding protein 0.025 0.1481 0.1613
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Plasmodium vivax glyoxalase I, putative 0.0044 0.0161 0.0698
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0032 0.0088 0.0271
Echinococcus granulosus heat shock protein 0.0037 0.0119 0.0129
Echinococcus granulosus twik family of potassium channels 0.0021 0.0013 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.014 0.0828
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0201 0.0623
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.0514 0.0559
Leishmania major cytochrome p450-like protein 0.0022 0.0024 0.0226
Schistosoma mansoni rab6-interacting 0.006 0.0265 0.0288
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0041 0.014 0.0828
Plasmodium vivax multidomain scavenger receptor, putative 0.006 0.0265 0.1152
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0014 0.0073
Echinococcus granulosus potassium channel subfamily K 0.0021 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0038
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0022 0.0024 0.007
Loa Loa (eye worm) hypothetical protein 0.0041 0.014 0.0429
Mycobacterium ulcerans hypothetical protein 0.0044 0.0161 0.0498
Leishmania major heat shock protein 83-1 0.0037 0.0119 0.1187
Schistosoma mansoni biogenic amine receptor 0.0088 0.0442 0.0481
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0168 0.0956 0.0956
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0032 0.0088 0.0088
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0022 0.0024 0.007
Echinococcus multilocularis carbonic anhydrase 0.0033 0.0089 0.0089
Entamoeba histolytica acyl-CoA synthetase, putative 0.005 0.0201 0.1088
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0099 0.0514 0.0559
Leishmania major metacaspase, putative 0.0026 0.0045 0.0437
Schistosoma mansoni neuroligin 3 (S09 family) 0.0131 0.0716 0.078
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0038
Trichomonas vaginalis heat shock protein, putative 0.003 0.007 0.0415
Brugia malayi Serotonin receptor 0.0088 0.0442 0.1354
Schistosoma mansoni metabotropic glutamate receptor 0.0141 0.0781 0.085
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0291 0.2943
Echinococcus granulosus carbonic anhydrase 0.0033 0.0089 0.0097
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0014 0.0063
Plasmodium falciparum heat shock protein 90 0.0037 0.0119 0.0516
Trypanosoma cruzi cytochrome P450, putative 0.0022 0.0024 0.0226
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0131 0.0716 0.2242
Schistosoma mansoni cytochrome P450 0.0022 0.0024 0.0026
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0143 0.0792 0.0863
Loa Loa (eye worm) RNA binding protein 0.025 0.1481 0.454
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 21 0.0021 0.0013 0.0038
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0319 0.1917 0.2088
Loa Loa (eye worm) TAR-binding protein 0.025 0.1481 0.454
Echinococcus multilocularis caspase 2 0.0026 0.0045 0.0045
Giardia lamblia Replication factor C, subunit 1 0.0041 0.014 0.0819
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0088 0.0442 0.0481
Brugia malayi thymidylate synthase 0.0159 0.0898 0.2754
Echinococcus multilocularis calcium activated potassium channel variant 0.0021 0.0013 0.0012
Schistosoma mansoni opsin-like receptor 0.0088 0.0442 0.0481
Echinococcus granulosus tar DNA binding protein 0.025 0.1481 0.1613
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0022 0.0024 0.007
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.0024 0.0074
Echinococcus granulosus carboxylesterase 5A 0.0529 0.3261 0.3552
Entamoeba histolytica heat shock protein 90, putative 0.0037 0.0119 0.0643
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0088 0.0442 0.0481
Trypanosoma cruzi extracellular receptor, putative 0.0031 0.0077 0.0758
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0147 0.0819 0.0892
Leishmania major GTP-binding protein, putative 0.0021 0.0014 0.0126
Echinococcus multilocularis rhodopsin orphan GPCR 0.0088 0.0442 0.0441
Schistosoma mansoni gliotactin 0.0131 0.0716 0.078
Echinococcus granulosus expressed conserved protein 0.013 0.0713 0.0776
Echinococcus granulosus metabotropic glutamate receptor 5 0.0349 0.2112 0.23
Echinococcus granulosus nmda type glutamate receptor 0.0031 0.0077 0.0083
Trichomonas vaginalis conserved hypothetical protein 0.0132 0.0722 0.4285
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0021 0.0013 0.0072
Schistosoma mansoni tar DNA-binding protein 0.025 0.1481 0.1613
Loa Loa (eye worm) hypothetical protein 0.0529 0.3261 1
Loa Loa (eye worm) hypothetical protein 0.005 0.0201 0.0615
Echinococcus granulosus ecdysone induced protein 78C 0.0032 0.0088 0.0096
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0107 0.0329
Onchocerca volvulus 0.0131 0.0716 0.4014
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.0471 0.0512
Trypanosoma brucei heat shock protein 90, putative 0.0037 0.0119 0.1187
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0039 0.0129 0.0129
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0282 0.1684 0.9151
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0027 0.025
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.1684 1
Loa Loa (eye worm) hypothetical protein 0.0349 0.2112 0.6477
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0 0.0001
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0021 0.0016 0.0084
Schistosoma mansoni carbonic anhydrase 0.0033 0.0089 0.0097
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0168 0.0956 0.1042
Echinococcus granulosus neuropeptide receptor 0.0088 0.0442 0.0481
Echinococcus multilocularis transcription factor btf3 0.0034 0.0101 0.01
Echinococcus granulosus caspase 0.0096 0.0494 0.0537
Onchocerca volvulus 0.0037 0.0116 0.0648
Onchocerca volvulus 0.0088 0.0442 0.2474
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0027 0.0146
Trypanosoma cruzi metacaspase, putative 0.0026 0.0045 0.0437
Leishmania major heat shock protein 83-1 0.0037 0.0119 0.1187
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0022 0.0024 0.007
Leishmania major 4-coumarate:coa ligase-like protein 0.005 0.0201 0.2022
Echinococcus granulosus Niemann Pick C1 protein 0.0438 0.2681 0.2921
Brugia malayi Bromodomain containing protein 0.0075 0.0363 0.1114
Brugia malayi ORL1-like opioid receptor 0.0088 0.0442 0.1354
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0032 0.0088 0.0271
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0039 0.0129 0.0129
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0022 0.0024 0.007
Leishmania major importin beta-1 subunit, putative 0.0023 0.0028 0.0264
Trichomonas vaginalis spcc417.12 protein, putative 0.0131 0.0716 0.4253
Echinococcus multilocularis orexin receptor type 2 0.0088 0.0442 0.0441
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0027 0.0077
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0096 0.0494 0.0537
Brugia malayi putative neuropeptide receptor 0.0088 0.0442 0.1354
Plasmodium falciparum endoplasmin, putative 0.0023 0.0027 0.0117
Trypanosoma cruzi cruzipain precursor, putative 0.0064 0.0291 0.2943
Onchocerca volvulus 0.0159 0.0898 0.5032
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.0046 0.0172 0.0962
Echinococcus granulosus atrial natriuretic peptide receptor 0.0031 0.0077 0.0083
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0088 0.0442 0.0441
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0088 0.0442 0.0481
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.0088 0.0271
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0099 0.0514 0.1576
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0022 0.0024 0.007
Echinococcus granulosus nmda type glutamate receptor 0.0029 0.0069 0.0075
Echinococcus multilocularis ecdysone induced protein 78C 0.0032 0.0088 0.0088
Echinococcus multilocularis neuropeptides capa receptor 0.0088 0.0442 0.0441
Giardia lamblia Grp94/Hsp90 0.003 0.007 0.0406
Brugia malayi hypothetical protein 0.006 0.0265 0.0813
Schistosoma mansoni lipoxygenase 0.0168 0.0956 0.1042
Brugia malayi isocitrate dehydrogenase 0.0054 0.0226 0.0693
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0088 0.0442 0.0481
Leishmania major hypothetical protein, conserved 0.0049 0.0195 0.1964
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0088 0.0442 0.0441
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0027 0.0845
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0037 0.012 0.037
Schistosoma mansoni microtubule-associated protein tau 0.1456 0.918 1
Echinococcus granulosus endoplasmin 0.003 0.007 0.0076
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0038
Echinococcus granulosus rhodopsin orphan GPCR 0.0088 0.0442 0.0481
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.014 0.0828
Brugia malayi Twik (KCNK-like) family of potasium channels, alpha subunit 40 0.0021 0.0013 0.0038
Echinococcus granulosus carbonic anhydrase 0.0033 0.0089 0.0097
Echinococcus granulosus lipoxygenase domain containing protein 0.006 0.0265 0.0288
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.006 0.0265 0.0288
Trichomonas vaginalis heat shock protein, putative 0.0023 0.0027 0.0157
Echinococcus granulosus alpha 1A adrenergic receptor 0.0088 0.0442 0.0481
Giardia lamblia Fructose-bisphosphate aldolase 0.0282 0.1684 1
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0024 0.0037 0.0353
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0054 0.0226 0.0226
Schistosoma mansoni tyrosine kinase 0.0034 0.01 0.0109
Schistosoma mansoni hypothetical protein 0.0022 0.0022 0.0023
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0054 0.0226 0.0982
Echinococcus multilocularis receptor type guanylyl cyclase 0.0034 0.01 0.01
Leishmania major cathepsin L-like protease 0.0064 0.0291 0.2943
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0196 0.1135 0.348
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0239 0.1408 0.1407
Entamoeba histolytica transcription factor BTF3, putative 0.0034 0.0101 0.0545
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0038
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0002 0.0002
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0022 0.0024 0.007
Trypanosoma cruzi PAB1-binding protein , putative 0.0049 0.0195 0.1964
Onchocerca volvulus 0.0041 0.014 0.0784
Echinococcus granulosus neuropeptide FF receptor 2 0.0088 0.0442 0.0481
Brugia malayi RE15519p 0.0088 0.0442 0.1354
Echinococcus granulosus caspase 2 0.0026 0.0045 0.0049
Echinococcus granulosus g protein coupled receptor 0.0088 0.0442 0.0481
Loa Loa (eye worm) CYP4Cod1 0.0022 0.0024 0.0074
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0037 0.012 0.037
Loa Loa (eye worm) hypothetical protein 0.0037 0.012 0.0368
Brugia malayi Dopamine receptor protein 2 0.0088 0.0442 0.1354
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 7 0.0021 0.0013 0.0038
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0088 0.0088
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0081 0.0398 0.0433
Schistosoma mansoni hypothetical protein 0.0083 0.0413 0.045
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.003 0.007 0.0695
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0291 0.2943
Schistosoma mansoni DNA ligase IV 0.0041 0.014 0.0152
Schistosoma mansoni topbp1 0.0041 0.014 0.0152
Echinococcus multilocularis caspase 3 0.007 0.033 0.0329
Echinococcus granulosus carbonic anhydrase 0.0033 0.0089 0.0097
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0038
Brugia malayi RNA, U transporter 1 0.0081 0.0396 0.1214
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 19. C. elegans unc-58 ortholog 0.0021 0.0013 0.0038
Brugia malayi hypothetical protein 0.0041 0.014 0.0429
Loa Loa (eye worm) hypothetical protein 0.0055 0.023 0.0706
Schistosoma mansoni biogenic amine receptor 0.0088 0.0442 0.0481
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0159 0.0898 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.0034 0.01 0.0307
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0032 0.0088 0.0096
Loa Loa (eye worm) hypothetical protein 0.0032 0.0088 0.0271
Schistosoma mansoni thyroid hormone receptor 0.0032 0.0088 0.0096
Trypanosoma brucei heat shock protein, putative 0.0037 0.0119 0.1187
Entamoeba histolytica hypothetical protein 0.0023 0.0027 0.0142
Echinococcus granulosus potassium channel subfamily K 8 0.0021 0.0013 0.0013
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0045 0.0264
Loa Loa (eye worm) hypothetical protein 0.0041 0.014 0.0429
Onchocerca volvulus Neuropeptide F receptor homolog 0.0088 0.0442 0.2474
Loa Loa (eye worm) neuropeptide F receptor 0.0088 0.0442 0.1354
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0471 0.2793
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0038
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0038
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0032 0.0088 0.0271
Trypanosoma cruzi heat shock protein 85, putative 0.0037 0.0119 0.1187
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0088 0.0442 0.0441
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0083 0.0413 0.0413
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.0514 0.0559
Loa Loa (eye worm) hypothetical protein 0.0529 0.3261 1
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0039 0.0129 0.0129
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0031 0.0077 0.0235
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0062 0.0612
Loa Loa (eye worm) hypothetical protein 0.0032 0.0088 0.0271
Schistosoma mansoni twik family of potassium channels-related 0.0021 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0032 0.0088 0.0271
Mycobacterium ulcerans ion transport protein 0.0021 0.0013 0.0033
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Trichomonas vaginalis ran, putative 0.0021 0.0014 0.0083
Echinococcus multilocularis serotonin receptor 0.0088 0.0442 0.0441
Toxoplasma gondii isocitrate dehydrogenase 0.0054 0.0226 0.0982
Echinococcus granulosus microtubule associated protein 2 0.1456 0.918 1
Leishmania major hypothetical protein, conserved 0.0021 0.0013 0.0107
Loa Loa (eye worm) hypothetical protein 0.005 0.0201 0.0615
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0471 0.2793
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0033 0.0089 0.0273
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0024 0.0037 0.016
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Schistosoma mansoni heat shock protein 0.0037 0.0119 0.0129
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0022 0.0024 0.007
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0143 0.0793 0.0863
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0032 0.0088 0.0096
Plasmodium falciparum carbonic anhydrase 0.0033 0.0089 0.0387
Schistosoma mansoni twik family of potassium channels-related 0.0021 0.0013 0.0013
Leishmania major 4-coumarate:coa ligase-like protein 0.005 0.0201 0.2022
Toxoplasma gondii hypothetical protein 0.0033 0.0089 0.0387
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0038
Echinococcus granulosus rhodopsin orphan GPCR 0.0088 0.0442 0.0481
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.1684 1
Echinococcus multilocularis beta adrenergic receptor kinase 0.002 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0038
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0032 0.0088 0.0096
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 38. C. elegans sup-9 ortholog 0.0021 0.0013 0.0038
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Echinococcus multilocularis allatostatin A receptor 0.0088 0.0442 0.0441
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.005 0.0201 0.0623
Loa Loa (eye worm) 4-hydroxyphenylpyruvate dioxygenase 0.0298 0.1785 0.5474
Brugia malayi G-protein coupled receptor 0.0088 0.0442 0.1354
Trypanosoma brucei choline/ethanolamine kinase 0.0037 0.0116 0.1156
Loa Loa (eye worm) hypothetical protein 0.0081 0.0398 0.1221
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0033 0.0089 0.0273
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0143 0.0793 0.805
Schistosoma mansoni amine GPCR 0.0088 0.0442 0.0481
Schistosoma mansoni bromodomain containing protein 0.0064 0.0288 0.0313
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Trypanosoma brucei Metacaspase-4 0.0026 0.0045 0.0437
Entamoeba histolytica hypothetical protein 0.0147 0.0819 0.4448
Loa Loa (eye worm) RGC/RGC protein kinase 0.0034 0.01 0.0307
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.1684 1
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0088 0.0442 0.1354
Brugia malayi hypothetical protein 0.0019 0 0.0001
Schistosoma mansoni glutamate receptor NMDA 0.0039 0.0129 0.014
Loa Loa (eye worm) hypothetical protein 0.0477 0.2924 0.8967
Trypanosoma brucei heat shock protein, putative 0.0037 0.0119 0.1187
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0092 0.0471 0.4772
Brugia malayi PHD-finger family protein 0.0025 0.0041 0.0127
Mycobacterium ulcerans hypothetical protein 0.0044 0.0161 0.0498
Trypanosoma brucei calcium/potassium channel (CAKC), putative 0.0021 0.0013 0.0107
Echinococcus multilocularis carbonic anhydrase II 0.0143 0.0793 0.0792
Echinococcus multilocularis neuropeptide receptor 0.0088 0.0442 0.0441
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0039 0.0129 0.014
Entamoeba histolytica serine/threonine protein kinase, putative 0.0092 0.0471 0.2556
Treponema pallidum heat shock protein 90 0.003 0.007 0.0406
Mycobacterium ulcerans hypothetical protein 0.0044 0.0161 0.0498
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.0088 0.0271
Loa Loa (eye worm) TWK-7 protein 0.0021 0.0013 0.0038
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0022 0.0024 0.007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0088 0.0442 0.0481
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0022 0.0022 0.0021
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0088 0.0442 0.0481
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.005 0.0201 0.2019
Brugia malayi Carboxylesterase family protein 0.0131 0.0716 0.2197
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0041 0.014 0.0828
Echinococcus multilocularis sentrin specific protease 7 0.0143 0.0792 0.0792
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0147 0.0819 0.0818
Echinococcus granulosus heat shock protein 90 0.0037 0.0119 0.0129
Echinococcus multilocularis fmrfamide receptor 0.0088 0.0442 0.0441
Schistosoma mansoni hypothetical protein 0.0062 0.0278 0.0302
Schistosoma mansoni hypothetical protein 0.0083 0.0413 0.045
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0022 0.0024 0.007
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0032 0.0088 0.0271
Brugia malayi cytochrome P450 0.0022 0.0024 0.0074
Loa Loa (eye worm) hypothetical protein 0.0049 0.0195 0.0598
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0021 0.0013 0.0072
Loa Loa (eye worm) carbonic anhydrase 3 0.0143 0.0793 0.2431
Brugia malayi AMP-binding enzyme family protein 0.005 0.0201 0.0615
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0 0.0001
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0045 0.0264
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0027 0.0077
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0032 0.0088 0.0271
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0032 0.0088 0.0096
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0027 0.0116
Leishmania major cathepsin L-like protease 0.0064 0.0291 0.2943
Toxoplasma gondii ion channel protein 0.0021 0.0013 0.0054
Echinococcus multilocularis twik family of potassium channels 0.0021 0.0013 0.0012
Leishmania major potassium channel subunit-like protein 0.0021 0.0013 0.0107
Brugia malayi steroid hormone receptor 0.0032 0.0088 0.0271
Brugia malayi MH2 domain containing protein 0.0115 0.0618 0.1894
Echinococcus granulosus dro:myosuppressin receptor 0.0088 0.0442 0.0481
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0088 0.0442 0.0481
Echinococcus granulosus GPCR family 2 0.0062 0.0278 0.0302
Schistosoma mansoni histamine h1 receptor 0.0088 0.0442 0.0481
Loa Loa (eye worm) doublecortin family protein 0.006 0.0265 0.0813
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0529 0.3261 0.3552
Plasmodium vivax endoplasmin, putative 0.0037 0.0119 0.0516
Echinococcus multilocularis zinc finger protein 0.002 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0038
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0002 0.0006
Plasmodium vivax potassium channel, putative 0.0021 0.0013 0.0054
Echinococcus multilocularis ethanolamine kinase 2 0.0037 0.0116 0.0115
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0365 0.2165
Echinococcus multilocularis Niemann Pick C1 protein 0.0438 0.2681 0.2681
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0022 0.0024 0.007
Brugia malayi Choline/ethanolamine kinase family protein 0.0037 0.0116 0.0355
Trichomonas vaginalis endoplasmin, putative 0.0023 0.0027 0.0157
Schistosoma mansoni hypothetical protein 0.006 0.0265 0.0288
Echinococcus granulosus sterol regulatory element binding protein 0.0132 0.0722 0.0786
Brugia malayi Dopamine receptor 0.0088 0.0442 0.1354
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0291 0.2943
Leishmania major calcium/potassium channel (CAKC), putative 0.0021 0.0013 0.0107
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0031 0.0077 0.0235
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Loa Loa (eye worm) hypothetical protein 0.0032 0.0088 0.0271
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Entamoeba histolytica calcium-gated potassium channel protein, putative 0.0021 0.0013 0.0066
Brugia malayi lactoylglutathione lyase 0.0044 0.0161 0.0493
Trypanosoma brucei PAB1-binding protein , putative 0.0049 0.0195 0.1964
Brugia malayi Endoplasmin precursor 0.0037 0.0119 0.0364
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0 0.0001
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0173 0.0984 1
Loa Loa (eye worm) hypothetical protein 0.0131 0.0716 0.2197
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0045 0.0264
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0054 0.0226 0.0226
Loa Loa (eye worm) G-protein coupled receptor 0.0088 0.0442 0.1354
Leishmania major basic transcription factor 3a, putative 0.0034 0.0101 0.1004
Brugia malayi Cytochrome P450 family protein 0.0022 0.0024 0.0074
Schistosoma mansoni hypothetical protein 0.0046 0.0172 0.0187
Brugia malayi AMP-binding enzyme family protein 0.005 0.0201 0.0615
Schistosoma mansoni neuropeptide f receptor 76f 0.0088 0.0442 0.0481
Echinococcus granulosus replication factor c subunit 1 0.0041 0.014 0.0152
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0024 0.0037 0.004
Toxoplasma gondii phosphotransferase enzyme family protein 0.0037 0.0116 0.0502
Leishmania major heat shock protein 83-1 0.0037 0.0119 0.1187
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0045 0.0264
Loa Loa (eye worm) hypothetical protein 0.0019 0 0.0001
Entamoeba histolytica acyl-coA synthetase, putative 0.005 0.0201 0.1088
Brugia malayi hypothetical protein 0.006 0.0265 0.0813
Schistosoma mansoni growth hormone secretagogue receptor 0.0088 0.0442 0.0481
Schistosoma mansoni ran 0.0021 0.0014 0.0015
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Schistosoma mansoni neuropeptide receptor 0.0088 0.0442 0.0481
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0291 0.2943
Schistosoma mansoni opsin-like receptor 0.0088 0.0442 0.0481
Brugia malayi Carboxylesterase family protein 0.0131 0.0716 0.2197
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0088 0.0442 0.1354
Loa Loa (eye worm) hypothetical protein 0.0031 0.0077 0.0235
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0021 0.0013 0.0072
Mycobacterium ulcerans biphenyl-2,3-diol 1,2-dioxygenase 0.0044 0.0161 0.0498
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0088 0.0442 0.1354
Echinococcus multilocularis rhodopsin orphan GPCR 0.0088 0.0442 0.0441
Schistosoma mansoni loxhd1 0.006 0.0265 0.0288
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Loa Loa (eye worm) hypothetical protein 0.0131 0.0716 0.2197
Echinococcus multilocularis caspase 0.0096 0.0494 0.0493
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0088 0.0442 0.0481
Loa Loa (eye worm) hypothetical protein 0.0041 0.014 0.0429
Loa Loa (eye worm) neuropeptide F receptor 0.0088 0.0442 0.1354
Loa Loa (eye worm) TWK-28 protein 0.0021 0.0013 0.0038
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0022 0.0024 0.007
Echinococcus granulosus fetal alzheimer antigen falz 0.0023 0.0026 0.0028
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0014 0.0063
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0092 0.0471 0.047
Entamoeba histolytica heat shock protein 90, putative 0.0037 0.0119 0.0643
Mycobacterium tuberculosis Conserved protein 0.0044 0.0161 0.0498
Schistosoma mansoni nuclear hormone receptor 0.0032 0.0088 0.0096
Brugia malayi photoreceptor-specific nuclear receptor 0.0032 0.0088 0.0271
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0032 0.0088 0.0271
Echinococcus granulosus tm gpcr rhodopsin 0.0088 0.0442 0.0481
Schistosoma mansoni endoplasmin 0.0037 0.0119 0.0129
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0037 0.012 0.8384
Brugia malayi hypothetical protein 0.0021 0.0013 0.0038
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0038
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0 0.0001
Schistosoma mansoni neuropeptide F-like receptor 0.0088 0.0442 0.0481
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0088 0.0442 0.0441
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0022 0.0024 0.007
Trypanosoma cruzi polo-like protein kinase, putative 0.0092 0.0471 0.4772
Brugia malayi AKH receptor 0.0088 0.0442 0.1354
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0032 0.0088 0.0096
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.025 0.1481 0.454
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0088 0.0442 0.0481
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0159 0.0898 0.9123
Loa Loa (eye worm) hypothetical protein 0.0032 0.0088 0.0271
Loa Loa (eye worm) transcription factor SMAD2 0.0115 0.0618 0.1894
Echinococcus granulosus dual specificity mitogen activated protein 0.0173 0.0984 0.1072
Schistosoma mansoni hypothetical protein 0.0062 0.0278 0.0302
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.002 0.0009 0.0028
Leishmania major heat shock protein 83-1 0.0037 0.0119 0.1187
Toxoplasma gondii t-complex protein beta subunit 0.0024 0.0037 0.016
Plasmodium falciparum T-complex protein 1 subunit beta 0.0024 0.0037 0.016
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0159 0.0898 0.0978
Echinococcus granulosus choline:ethanolamine kinase 0.0379 0.2301 0.2507
Loa Loa (eye worm) hypothetical protein 0.0032 0.0088 0.0271
Echinococcus multilocularis G protein coupled receptor 139 0.0088 0.0442 0.0441
Brugia malayi Bromodomain containing protein 0.0039 0.0127 0.039
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0022 0.0024 0.007
Schistosoma mansoni tar DNA-binding protein 0.025 0.1481 0.1613
Echinococcus granulosus orexin receptor type 2 0.0088 0.0442 0.0481
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0088 0.0442 0.0441
Schistosoma mansoni choline kinase 0.0037 0.0116 0.0126
Onchocerca volvulus 0.0088 0.0442 0.2474
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0088 0.0442 0.0481
Toxoplasma gondii LsmAD domain-containing protein 0.0049 0.0195 0.0847
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0032 0.0088 0.0096
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0022 0.0024 0.007
Echinococcus multilocularis potassium channel subfamily K 8 0.0021 0.0013 0.0012
Plasmodium vivax potassium channel, putative 0.0021 0.0013 0.0054
Trichomonas vaginalis heat shock protein, putative 0.003 0.007 0.0415
Echinococcus granulosus G protein coupled receptor 139 0.0088 0.0442 0.0481
Loa Loa (eye worm) T-complex protein 1 0.0024 0.0037 0.0113
Schistosoma mansoni thyroid hormone receptor 0.0032 0.0088 0.0096
Loa Loa (eye worm) S-phase kinase-associated protein 1A 0.0021 0.0013 0.0038
Leishmania major heat shock protein 83-1 0.0037 0.0119 0.1187
Loa Loa (eye worm) hypothetical protein 0.0076 0.0367 0.1126
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0173 0.0984 1
Brugia malayi Carboxylesterase family protein 0.0131 0.0716 0.2197
Onchocerca volvulus 0.0088 0.0442 0.2474
Loa Loa (eye worm) G-protein coupled receptor 0.0088 0.0442 0.1354
Loa Loa (eye worm) carboxylesterase 0.0131 0.0716 0.2197
Trypanosoma cruzi heat shock protein 85, putative 0.003 0.007 0.0695
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 35 0.0021 0.0013 0.0038
Echinococcus granulosus rhodopsin orphan GPCR 0.0088 0.0442 0.0481
Echinococcus multilocularis g protein coupled receptor 0.0088 0.0442 0.0441
Loa Loa (eye worm) hypothetical protein 0.0132 0.0722 0.2214
Echinococcus granulosus heat shock protein 90 0.003 0.007 0.0076
Plasmodium vivax heat shock protein 86, putative 0.0037 0.0119 0.0516
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0041 0.014 0.0828
Loa Loa (eye worm) hypothetical protein 0.0196 0.1135 0.348
Onchocerca volvulus 0.0131 0.0716 0.4014
Schistosoma mansoni amine GPCR 0.0088 0.0442 0.0481
Trypanosoma cruzi polo-like protein kinase, putative 0.0092 0.0471 0.4772
Schistosoma mansoni caspase-7 (C14 family) 0.0096 0.0494 0.0537
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.1684 1
Leishmania major carbonic anhydrase-like protein 0.0143 0.0793 0.805
Echinococcus multilocularis g protein coupled receptor 0.0088 0.0442 0.0441
Echinococcus multilocularis neuropeptides capa receptor 0.0088 0.0442 0.0441
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0024 0.0037 0.004
Echinococcus granulosus transcription factor btf3 0.0034 0.0101 0.0109
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0099 0.0514 0.1576
Echinococcus granulosus RUN 0.006 0.0265 0.0288
Chlamydia trachomatis DNA ligase 0.0041 0.014 1
Trypanosoma brucei metacaspase MCA2 0.0026 0.0045 0.0437
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0131 0.0716 0.2242
Plasmodium vivax basic transcription factor 3b, putative 0.0034 0.0101 0.0437
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0021 0.0016 0.0084
Schistosoma mansoni apoptosis regulator bax 0.0083 0.0413 0.045
Onchocerca volvulus 0.0088 0.0442 0.2474
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0034 0.01 0.0561
Onchocerca volvulus 0.0021 0.0013 0.007
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0032 0.0088 0.0088
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0021 0.0016 0.0044
Entamoeba histolytica hypothetical protein 0.0147 0.0819 0.4448
Trypanosoma brucei heat shock protein, putative 0.0037 0.0119 0.1187
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0024 0.0037 0.004
Plasmodium vivax ataxin-2 like protein, putative 0.0049 0.0195 0.0847
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0088 0.0442 0.1354
Schistosoma mansoni metabotropic glutamate receptor 0.0239 0.1408 0.1533
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0038
Schistosoma mansoni neuropeptide receptor 0.0088 0.0442 0.0481
Schistosoma mansoni topbp1 0.0041 0.014 0.0152
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0349 0.2112 0.2112
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0173 0.0984 0.3018
Echinococcus granulosus importin subunit beta 1 0.0028 0.0062 0.0067
Schistosoma mansoni myosin xvIII 0.0088 0.0442 0.0481
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0022 0.0024 0.0226
Leishmania major 4-coumarate:coa ligase-like protein 0.005 0.0201 0.2022
Echinococcus multilocularis rhodopsin orphan GPCR 0.0088 0.0442 0.0441
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0038
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0471 0.2793
Echinococcus multilocularis sex peptide receptor 0.0088 0.0442 0.0441
Entamoeba histolytica hypothetical protein 0.0147 0.0819 0.4448
Schistosoma mansoni caspase-3 (C14 family) 0.0096 0.0494 0.0537
Brugia malayi hypothetical protein 0.0147 0.0819 0.2511
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0092 0.0471 0.1444
Loa Loa (eye worm) hypothetical protein 0.0041 0.014 0.0429
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0022 0.0024 0.007
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0027 0.0116
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Treponema pallidum DNA ligase (lig) 0.0041 0.014 0.0819
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0038
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0022 0.0024 0.007
Toxoplasma gondii NAC domain-containing protein 0.0034 0.0101 0.0437
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0159 0.0898 0.3902
Schistosoma mansoni twik family of potassium channels-related 0.0021 0.0013 0.0013
Schistosoma mansoni polycystin 1-related 0.006 0.0265 0.0288
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0138 0.0762 0.2385
Schistosoma mansoni hypothetical protein 0.0127 0.0692 0.0753
Loa Loa (eye worm) hypothetical protein 0.0307 0.184 0.5644
Loa Loa (eye worm) hypothetical protein 0.0031 0.0077 0.0235
Echinococcus multilocularis somatostatin receptor 0.0088 0.0442 0.0441
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Plasmodium vivax metacaspase 1, putative 0.0026 0.0045 0.0195
Loa Loa (eye worm) hypothetical protein 0.0021 0.0013 0.0038
Trichomonas vaginalis chaperonin, putative 0.0024 0.0037 0.0216
Echinococcus multilocularis neuropeptide Y receptor 0.0088 0.0442 0.0441
Trypanosoma brucei Heat shock protein 83, putative 0.0037 0.0119 0.1187
Echinococcus granulosus neuropeptides capa receptor 0.0088 0.0442 0.0481
Echinococcus multilocularis neuropeptide receptor 0.0088 0.0442 0.0441
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0045 0.0264
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0022 0.0024 0.007
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.1684 1
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Echinococcus granulosus acetylcholinesterase 0.0529 0.3261 0.3552
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0022 0.0024 0.007
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0041 0.014 0.0758
Toxoplasma gondii exonuclease III APE 0.0019 0.0002 0.0009
Echinococcus multilocularis lipoxygenase domain containing protein 0.006 0.0265 0.0265
Echinococcus multilocularis microtubule associated protein 2 0.1456 0.918 0.918
Echinococcus multilocularis BC026374 protein (S09 family) 0.0131 0.0716 0.0716
Toxoplasma gondii phosphotransferase enzyme family protein 0.0379 0.2301 1
Trypanosoma brucei heat shock protein, putative 0.0037 0.0119 0.1187
Loa Loa (eye worm) glutamate receptor 0.0285 0.1698 0.5208
Onchocerca volvulus Bile acid receptor homolog 0.0032 0.0088 0.0495
Brugia malayi sulfakinin receptor protein 0.0088 0.0442 0.1354
Echinococcus multilocularis Niemann Pick C1 protein 0.0307 0.184 0.184
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0009 0.001
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.003 0.007 0.495
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0027 0.0077
Schistosoma mansoni neuropeptide F-like receptor 0.0088 0.0442 0.0481
Loa Loa (eye worm) glutamate receptor 0.011 0.0585 0.1795
Plasmodium falciparum ethanolamine kinase 0.0037 0.0116 0.0502
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0088 0.0442 0.0481
Loa Loa (eye worm) hypothetical protein 0.012 0.065 0.1994
Echinococcus granulosus neuropeptides capa receptor 0.0088 0.0442 0.0481
Onchocerca volvulus 0.006 0.0265 0.1486
Loa Loa (eye worm) melatonin receptor type 1A 0.0088 0.0442 0.1354
Onchocerca volvulus 0.0081 0.0398 0.2231
Brugia malayi Steroid receptor seven-up type 2 0.0032 0.0088 0.0271
Loa Loa (eye worm) hypothetical protein 0.0088 0.0442 0.1354
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0022 0.0024 0.0226
Echinococcus multilocularis twik family of potassium channels 0.0021 0.0013 0.0012
Echinococcus multilocularis dro:myosuppressin receptor 0.0088 0.0442 0.0441
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0021 0.0013 0.0107
Trypanosoma cruzi choline ethanolamine kinase, putative 0.0037 0.0116 0.1156
Treponema pallidum fructose-bisphosphate aldolase 0.0282 0.1684 1
Schistosoma mansoni endoplasmin 0.0037 0.0119 0.0129
Echinococcus multilocularis TWiK family of potassium channels protein 7 0.0021 0.0013 0.0012
Mycobacterium ulcerans glyoxalase GloA 0.0044 0.0161 0.0498
Loa Loa (eye worm) hypothetical protein 0.0134 0.0738 0.2264
Echinococcus multilocularis FTZ F1 alpha 0.0032 0.0088 0.0088
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0062 0.0278 0.0302
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0088 0.0442 0.0441
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0045 0.0264
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0088 0.0442 0.0481
Trypanosoma cruzi heat shock protein 85, putative 0.0037 0.0119 0.1187
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0088 0.0442 0.0441
Giardia lamblia Kinase, STE STE20 0.0173 0.0984 0.5839
Mycobacterium ulcerans hypothetical protein 0.0044 0.0161 0.0498
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0054 0.0226 0.2281
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0033 0.0089 0.0273
Brugia malayi 4-hydroxyphenylpyruvate dioxygenase family protein 0.0298 0.1785 0.5474
Echinococcus granulosus BC026374 protein S09 family 0.0131 0.0716 0.078
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0039 0.0129 0.014
Echinococcus granulosus serotonin receptor 0.0088 0.0442 0.0481
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0045 0.0264
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0002 0.0009
Echinococcus multilocularis potassium channel subfamily K 0.0021 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0031 0.0077 0.0235
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0054 0.0226 0.2281
Loa Loa (eye worm) hypothetical protein 0.0044 0.0161 0.0493
Echinococcus granulosus caspase 3 0.007 0.033 0.0359
Schistosoma mansoni hypothetical protein 0.0088 0.0442 0.0481
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0022 0.0024 0.007
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0032 0.0088 0.0271
Echinococcus multilocularis neuropeptide receptor A26 0.054 0.3329 0.3329
Loa Loa (eye worm) hypothetical protein 0.0039 0.0128 0.0392
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0291 0.2943
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0099 0.0514 0.0559
Loa Loa (eye worm) hypothetical protein 0.0037 0.012 0.0368
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0076 0.0367 0.1126
Loa Loa (eye worm) hypothetical protein 0.0032 0.0088 0.0271
Schistosoma mansoni retinoic acid receptor RXR 0.0032 0.0088 0.0096
Onchocerca volvulus 0.0088 0.0442 0.2474
Brugia malayi GnHR receptor homolog 0.0088 0.0442 0.1354
Brugia malayi T-complex protein 1, beta subunit 0.0024 0.0037 0.0113
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.0021 0.0013 0.0038
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0022 0.0022 0.0023
Toxoplasma gondii heat shock protein 90, putative 0.0037 0.0119 0.0516
Mycobacterium tuberculosis Possible transmembrane cation transporter 0.0021 0.0013 0.0033

Activities

Activity type Activity value Assay description Source Reference
Adjusted Ki (binding) = 0.73 nM Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe grisea ChEMBL. 10386945
Adjusted Ki (binding) = 0.73 nM Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe grisea ChEMBL. 10386945
ED90 (functional) = 6.2 mg l-1 Concentration that affords 90% control of blast disease on rice plants by multiple rate foliar rice blast assay ChEMBL. 10386945
Ki (binding) = 0.73 nM Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe grisea ChEMBL. 10386945
Ki (binding) = 0.73 nM Inhibitory activity against scytalone dehydratase enzyme obtained from Magnaporthe grisea ChEMBL. 10386945
Ki (binding) = 20 pM Inhibition of scytalone dehydratase purified from Magnaporthe grisea ChEMBL. 10386946
Ki (binding) = 20 pM Inhibition of scytalone dehydratase purified from Magnaporthe grisea ChEMBL. 10386946

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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