Detailed information for compound 575084

Basic information

Technical information
  • TDR Targets ID: 575084
  • Name: (2E)-2-[4,5-dihydroxy-6-[3,4,5-trihydroxy-6-( hydroxymethyl)tetrahydropyran-2-yl]oxy-cycloh ex-2-en-1-ylidene]acetonitrile
  • MW: 329.303 | Formula: C14H19NO8
  • H donors: 6 H acceptors: 7 LogP: -3.29 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 2
  • SMILES: N#C/C=C/1\C=CC(C(C1OC1OC(CO)C(C(C1O)O)O)O)O
  • InChi: 1S/C14H19NO8/c15-4-3-6-1-2-7(17)9(18)13(6)23-14-12(21)11(20)10(19)8(5-16)22-14/h1-3,7-14,16-21H,5H2/b6-3+
  • InChiKey: WIIDBJNWXCWLKF-ZZXKWVIFSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • (2E)-2-[4,5-dihydroxy-6-[[3,4,5-trihydroxy-6-(hydroxymethyl)-2-tetrahydropyranyl]oxy]-1-cyclohex-2-enylidene]acetonitrile
  • (2E)-2-[4,5-dihydroxy-6-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-cyclohex-2-en-1-ylidene]ethanenitrile
  • (2E)-2-[4,5-dihydroxy-6-(3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl)oxy-cyclohex-2-en-1-ylidene]acetonitrile
  • (2E)-2-[4,5-dihydroxy-6-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxycyclohex-2-en-1-ylidene]acetonitrile
  • griffonin
  • (2E)-2-[4,5-dihydroxy-6-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1-cyclohex-2-enylidene]acetonitrile
  • 2-[4,5-dihydroxy-6-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1-cyclohex-2-enylidene]acetonitrile
  • (2E)-2-[4,5-dihydroxy-6-[3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-1-cyclohex-2-enylidene]acetonitrile
  • 2-[4,5-dihydroxy-6-[3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-1-cyclohex-2-enylidene]acetonitrile
  • 2-[4,5-dihydroxy-6-[[3,4,5-trihydroxy-6-(hydroxymethyl)-2-tetrahydropyranyl]oxy]-1-cyclohex-2-enylidene]acetonitrile
  • 2-[4,5-dihydroxy-6-(3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl)oxy-1-cyclohex-2-enylidene]acetonitrile
  • (2E)-2-[4,5-dihydroxy-6-(3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl)oxy-1-cyclohex-2-enylidene]acetonitrile
  • 2-[4,5-dihydroxy-6-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1-cyclohex-2-enylidene]ethanenitrile
  • (2E)-2-[4,5-dihydroxy-6-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1-cyclohex-2-enylidene]ethanenitrile
  • 63492-69-3
  • NSC290807
  • Lithospermum ruderale glycoside

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni FFA transport protein 0.1048 0.2915 0.4235
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.1132 0.3157 1
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0033 0.0017 0.0013
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0068 0.0137
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0376 0.0996 0.2399
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0036 0.0026 0.0121
Trypanosoma cruzi hypothetical protein, conserved 0.0216 0.0541 0.1815
Schistosoma mansoni serine/threonine protein kinase 0.0108 0.023 0.0326
Brugia malayi tailless protein 0.0054 0.0077 0.016
Brugia malayi Pre-SET motif family protein 0.0214 0.0533 0.127
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0108 0.023 0.1492
Schistosoma mansoni methyl-cpg binding protein mbd 0.005 0.0066 0.0087
Loa Loa (eye worm) hypothetical protein 0.0098 0.0204 0.047
Brugia malayi PHD-finger family protein 0.0062 0.01 0.0215
Brugia malayi Muscleblind-like protein 0.0583 0.1587 0.3838
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0098 0.0204 0.0663
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0376 0.0996 0.1054
Schistosoma mansoni ap endonuclease 0.0099 0.0204 0.0288
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0117 0.0256 0.0271
Echinococcus multilocularis jumonji domain containing protein 0.0203 0.0502 0.0532
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0098 0.0204 0.0654
Loa Loa (eye worm) hypothetical protein 0.0086 0.0169 0.0386
Brugia malayi hypothetical protein 0.006 0.0095 0.0205
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.023 0.0465
Echinococcus granulosus dna polymerase kappa 0.0058 0.009 0.012
Trichomonas vaginalis alpha-glucosidase, putative 0.0072 0.0128 0.0258
Leishmania major 4-coumarate:coa ligase-like protein 0.0098 0.0204 0.0663
Trichomonas vaginalis conserved hypothetical protein 0.0238 0.0603 0.1221
Echinococcus granulosus sodium:myo inositol cotransporter 0.0076 0.0141 0.0195
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0311 0.0812 0.0798
Toxoplasma gondii PHD-finger domain-containing protein 0.0146 0.0339 0.2222
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0048 0.0059 0.0104
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0177 0.0428 0.0612
Echinococcus granulosus snurportin 1 0.1267 0.3541 0.5146
Trichomonas vaginalis ap endonuclease, putative 0.0099 0.0204 0.0412
Loa Loa (eye worm) jmjC domain-containing protein 0.0301 0.0783 0.188
Trichomonas vaginalis beta-galactosidase, putative 0.0238 0.0603 0.1221
Echinococcus granulosus histone acetyltransferase KAT2B 0.0703 0.1931 0.2801
Echinococcus multilocularis mothers against decapentaplegic 5 0.0049 0.0062 0.0065
Schistosoma mansoni hypothetical protein 0.0177 0.0428 0.0613
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0037 0.0155
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0098 0.0204 0.0584
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0047 0.0058 0.0073
Trypanosoma brucei pyruvate kinase 1, putative 0.0034 0.0021 0.0044
Loa Loa (eye worm) hypothetical protein 0.0114 0.025 0.0581
Trypanosoma brucei DNA polymerase IV, putative 0.0058 0.009 0.0508
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0067 0.0113 0.0341
Mycobacterium ulcerans acyl-CoA synthetase 0.0098 0.0204 0.0584
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.023 0.0465
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.004 0.0037 0.0081
Brugia malayi MH2 domain containing protein 0.0715 0.1966 0.4759
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0114 0.025 0.0354
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0098 0.0204 0.0584
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0114 0.025 0.0354
Loa Loa (eye worm) histone methyltransferase 0.0054 0.0078 0.0163
Brugia malayi Nuclear hormone receptor E75 0.0054 0.0077 0.016
Brugia malayi manba-prov protein 0.0077 0.0143 0.0322
Loa Loa (eye worm) hypothetical protein 0.0042 0.0042 0.0075
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0047 0.0058 0.0428
Schistosoma mansoni kinase 0.0052 0.0072 0.0095
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1756 0.4938 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0106 0.0226 0.0239
Toxoplasma gondii protein kinase, putative 0.0293 0.0759 0.5034
Mycobacterium leprae Probable pyruvate kinase PykA 0.0034 0.0021 0.0045
Brugia malayi Carboxylesterase family protein 0.0071 0.0124 0.0276
Loa Loa (eye worm) hypothetical protein 0.0054 0.0077 0.016
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0098 0.0204 0.0654
Schistosoma mansoni hypothetical protein 0.0096 0.0196 0.0276
Mycobacterium tuberculosis Probable lipase LipD 0.0552 0.15 0.1486
Brugia malayi Calcitonin receptor-like protein seb-1 0.0559 0.1518 0.367
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0552 0.15 0.1486
Echinococcus granulosus mitogen activated protein kinase 3 0.0108 0.023 0.0325
Loa Loa (eye worm) hypothetical protein 0.0053 0.0074 0.0154
Echinococcus multilocularis calcium dependent protein kinase 0.003 0.0007 0.0008
Echinococcus granulosus cpg binding protein 0.0165 0.0394 0.0563
Onchocerca volvulus 0.0096 0.0196 0.0392
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0058 0.009 0.0191
Trypanosoma cruzi fatty acid transporter protein-like, putative 0.1048 0.2915 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.009 0.0508
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0057 0.0084 0.0268
Leishmania major importin beta-1 subunit, putative 0.0096 0.0198 0.0641
Echinococcus granulosus RUN 0.0042 0.0042 0.005
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0057 0.0085 0.0662
Loa Loa (eye worm) hypothetical protein 0.0114 0.025 0.0581
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0021 0.0017
Echinococcus granulosus ecdysone induced protein 78C 0.0114 0.025 0.0353
Echinococcus multilocularis high affinity choline transporter 1 0.0076 0.0141 0.0149
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0099 0.0204 0.1316
Toxoplasma gondii HEAT repeat-containing protein 0.0119 0.0262 0.1702
Mycobacterium tuberculosis Conserved protein 0.0552 0.15 0.1486
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0054 0.0078 0.0083
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0108 0.023 0.0746
Leishmania major acetyl-CoA synthetase, putative 0.0098 0.0204 0.0663
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0103 0.0217 0.023
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0074 0.0154
Echinococcus granulosus L aminoadipate semialdehyde 0.017 0.0408 0.0583
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0128 0.0393
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0098 0.0204 0.0584
Echinococcus granulosus sodium:glucose cotransporter 0.0076 0.0141 0.0195
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.1267 0.3541 0.8595
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0037 0.0028 0.003
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0021 0.0023
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0016 0.0006
Loa Loa (eye worm) hypothetical protein 0.0114 0.025 0.0581
Brugia malayi photoreceptor-specific nuclear receptor 0.0114 0.025 0.0581
Leishmania major pyruvate kinase 0.0034 0.0021 0.0023
Loa Loa (eye worm) hypothetical protein 0.006 0.0095 0.0205
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0177 0.0428 0.1014
Echinococcus multilocularis L aminoadipate semialdehyde 0.017 0.0408 0.0431
Loa Loa (eye worm) Smad1 0.0049 0.0062 0.0124
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0075 0.0137 0.019
Loa Loa (eye worm) hypothetical protein 0.0054 0.0077 0.016
Brugia malayi MH1 domain containing protein 0.0049 0.0062 0.0124
Loa Loa (eye worm) hypothetical protein 0.0559 0.1518 0.367
Trichomonas vaginalis glucosylceramidase, putative 0.0287 0.0744 0.1505
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0168 0.0403 0.2646
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0014 0.0027
Loa Loa (eye worm) MH2 domain-containing protein 0.0049 0.0062 0.0124
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.004 0.0037 0.0039
Mycobacterium ulcerans glutaminase 0.0271 0.0697 0.2157
Toxoplasma gondii propionate-CoA ligase 0.0098 0.0204 0.1315
Echinococcus multilocularis lipoxygenase domain containing protein 0.0042 0.0042 0.0044
Toxoplasma gondii histone lysine methyltransferase SET1 0.0318 0.0832 0.5522
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.006 0.0095 0.0128
Trichomonas vaginalis penicillin-binding protein, putative 0.0552 0.15 0.3037
Loa Loa (eye worm) transcription factor SMAD2 0.0715 0.1966 0.476
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0123 0.0275 0.039
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.022 0.055 0.3635
Brugia malayi CXXC zinc finger family protein 0.0151 0.0354 0.0834
Trichomonas vaginalis penicillin-binding protein, putative 0.0552 0.15 0.3037
Mycobacterium ulcerans hypothetical protein 0.0552 0.15 0.4717
Schistosoma mansoni chromobox protein 0.0138 0.0316 0.0451
Schistosoma mansoni hypothetical protein 0.0626 0.171 0.2481
Trypanosoma brucei protein kinase, putative 0.0108 0.023 0.1456
Trichomonas vaginalis glucosylceramidase, putative 0.0199 0.049 0.0992
Mycobacterium ulcerans acyl-CoA synthetase 0.0098 0.0204 0.0584
Echinococcus granulosus lamin dm0 0.0031 0.0013 0.0008
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0033 0.0017 0.006
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0076 0.0141 0.0149
Brugia malayi conserved hypotetical protein 0.0054 0.0077 0.016
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0114 0.025 0.0354
Onchocerca volvulus Serine\/threonine kinase homolog 0.01 0.0208 0.0418
Loa Loa (eye worm) cytochrome P450 family protein 0.0037 0.0029 0.0044
Brugia malayi PHD-finger family protein 0.01 0.0208 0.0479
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0111 0.0333
Brugia malayi glutathione reductase 0.0137 0.0313 0.0734
Mycobacterium tuberculosis Probable lipase LipE 0.0552 0.15 0.1486
Brugia malayi CHE-14 protein 0.0041 0.004 0.007
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.009 0.0508
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0114 0.025 0.0353
Trichomonas vaginalis conserved hypothetical protein 0.0103 0.0217 0.0439
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0086 0.0169 0.0474
Echinococcus multilocularis PHD finger protein rhinoceros 0.0146 0.0339 0.0359
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0074 0.0097
Loa Loa (eye worm) hypothetical protein 0.017 0.0408 0.0965
Echinococcus multilocularis FTZ F1 alpha 0.0114 0.025 0.0264
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0077 0.0143 0.0279
Mycobacterium ulcerans lipase LipD 0.0552 0.15 0.4717
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0098 0.0204 0.0469
Onchocerca volvulus Protein ultraspiracle homolog 0.0114 0.025 0.0506
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0058 0.009 0.0264
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0535 0.1452 0.2104
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0086 0.0169 0.0474
Schistosoma mansoni cellular tumor antigen P53 0.0053 0.0074 0.0099
Echinococcus granulosus General substrate transporter 0.0089 0.0176 0.0246
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0086 0.0169 0.1084
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0108 0.023 0.0746
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0014 0.0027
Schistosoma mansoni pyruvate kinase 0.0034 0.0021 0.0021
Trypanosoma cruzi DNA polymerase kappa, putative 0.0058 0.009 0.026
Plasmodium falciparum calcium-dependent protein kinase 2 0.0033 0.0017 0.0076
Loa Loa (eye worm) PHD-finger family protein 0.0061 0.0097 0.0209
Echinococcus multilocularis Polycystic kidney disease protein 0.0042 0.0042 0.0044
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0098 0.0204 0.0584
Echinococcus multilocularis geminin 0.2434 0.6874 0.7274
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.0041 0.0091
Schistosoma mansoni cpg binding protein 0.0165 0.0394 0.0564
Mycobacterium leprae conserved hypothetical protein 0.0048 0.0059 0.0179
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0047 0.0058 0.0294
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0072 0.0128 0.0285
Onchocerca volvulus 0.0054 0.0077 0.0137
Leishmania major hypothetical protein, conserved 0.0062 0.0101 0.0304
Loa Loa (eye worm) hypothetical protein 0.0054 0.0077 0.016
Loa Loa (eye worm) carboxylesterase 0.0071 0.0124 0.0276
Mycobacterium ulcerans acyl-CoA synthetase 0.0098 0.0204 0.0584
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0214 0.0533 0.0563
Echinococcus multilocularis JmjC domain containing protein 4 0.0062 0.0101 0.0107
Schistosoma mansoni bromodomain containing protein 0.0213 0.0532 0.0764
Echinococcus multilocularis peptidase Clp (S14 family) 0.0057 0.0084 0.0089
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0098 0.0204 0.0584
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0208 0.0421
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0034 0.0021 0.0005
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0067 0.0113 0.0665
Entamoeba histolytica acyl-coA synthetase, putative 0.0098 0.0204 0.0391
Entamoeba histolytica acyl-CoA synthetase, putative 0.0098 0.0204 0.0391
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0101 0.0107
Echinococcus multilocularis importin subunit beta 1 0.0119 0.0262 0.0277
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0086 0.0169 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0072 0.0128 0.0258
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0208 0.0421
Brugia malayi SET domain containing protein 0.0034 0.0019 0.0018
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.006 0.0095 0.0205
Loa Loa (eye worm) hypothetical protein 0.006 0.0095 0.0205
Schistosoma mansoni hypothetical protein 0.0303 0.0789 0.1139
Trichomonas vaginalis chromobox protein, putative 0.0138 0.0316 0.0639
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0079 0.0159
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.0461 0.0933
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0047 0.0058 0.0336
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0114 0.025 0.0581
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD6 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.1034 0.2876 0.2865
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0047 0.0058 0.0151
Schistosoma mansoni hypothetical protein 0.0048 0.0059 0.0076
Echinococcus granulosus polycomb protein SCMH1 0.0047 0.0056 0.0071
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0071 0.0124 0.0172
Echinococcus multilocularis pyruvate kinase 0.0034 0.0021 0.0022
Echinococcus multilocularis lamin dm0 0.0031 0.0013 0.0013
Echinococcus multilocularis General substrate transporter 0.0089 0.0176 0.0186
Brugia malayi MH1 domain containing protein 0.0049 0.0062 0.0124
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0054 0.0077 0.0102
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1756 0.4938 1
Echinococcus multilocularis thioredoxin glutathione reductase 0.0137 0.0314 0.0332
Mycobacterium tuberculosis Probable oxidoreductase 0.0346 0.0911 0.0897
Brugia malayi hypothetical protein 0.006 0.0095 0.0205
Brugia malayi Importin beta-1 subunit 0.0119 0.0262 0.061
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.0217 0.0306
Brugia malayi chromobox protein homolog 3 0.0077 0.0143 0.0322
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0086 0.0169 0.7632
Schistosoma mansoni hypothetical protein 0.1267 0.3541 0.5147
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0086 0.0169 0.0564
Leishmania major acetyl-CoA synthetase, putative 0.0098 0.0204 0.0663
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0101 0.0137
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0057 0.0085 0.017
Onchocerca volvulus 0.0042 0.0042 0.0062
Echinococcus multilocularis jumonji domain containing 1A 0.0062 0.0101 0.0107
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0031 0.0013 0.0004
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0328 0.0859 0.1241
Echinococcus granulosus GTP binding nuclear protein Ran 0.0067 0.0113 0.0154
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.0461 0.0933
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0067 0.0113 0.0899
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0098 0.0204 0.0584
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0035 0.0022 0.0026
Brugia malayi jmjC domain containing protein 0.0062 0.0101 0.0219
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0096 0.0239
Trichomonas vaginalis chromobox protein, putative 0.0083 0.016 0.0323
Onchocerca volvulus 0.0107 0.0228 0.0459
Schistosoma mansoni smad1 5 8 and 0.0049 0.0062 0.0081
Leishmania major DNA polymerase kappa, putative 0.0058 0.009 0.0264
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0035 0.0022 0.0026
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0287 0.0744 0.1783
Leishmania major hypothetical protein, conserved 0.0101 0.0212 0.0691
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0058 0.009 0.0121
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0168 0.0403 0.2646
Entamoeba histolytica deoxycytidyl transferase, putative 0.0058 0.009 0.0159
Brugia malayi Nuclear hormone receptor-like 1 0.0114 0.025 0.0581
Echinococcus multilocularis ubiquitin specific protease 41 0.004 0.0037 0.0039
Trichomonas vaginalis alpha-glucosidase, putative 0.0072 0.0128 0.0258
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0098 0.0204 0.0188
Echinococcus multilocularis nuclear receptor nhr 48 0.0054 0.0077 0.0081
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0114 0.025 0.0353
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0114 0.025 0.0581
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0098 0.0204 0.0188
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0041 0.0039 0.0079
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0101 0.0137
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.004 0.0037 0.0063
Leishmania major 4-coumarate:coa ligase-like protein 0.0098 0.0204 0.0663
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0047 0.0058 0.0336
Leishmania major hypothetical protein, conserved 0.0045 0.0052 0.0132
Echinococcus granulosus lamin 0.0031 0.0013 0.0008
Loa Loa (eye worm) hypothetical protein 0.0098 0.0204 0.047
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0101 0.0137
Loa Loa (eye worm) mbt repeat family protein 0.0047 0.0056 0.0109
Brugia malayi serine/threonine-protein kinase plk-2 0.01 0.0208 0.0481
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0047 0.0058 0.0153
Schistosoma mansoni peptidase Clp (S14 family) 0.0086 0.0169 0.0237
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0031 0.0011 0.0005
Schistosoma mansoni rab6-interacting 0.0042 0.0042 0.0051
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0033 0.0017 0.006
Brugia malayi AMP-binding enzyme family protein 0.0098 0.0204 0.0469
Trichomonas vaginalis ap endonuclease, putative 0.0099 0.0204 0.0412
Entamoeba histolytica Ran family GTPase 0.0067 0.0113 0.0207
Schistosoma mansoni protein phosphatase 2C 0.0062 0.0101 0.0138
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0099 0.0204 0.1279
Echinococcus granulosus tumor protein p63 0.0363 0.0959 0.1385
Loa Loa (eye worm) hypothetical protein 0.0053 0.0074 0.0154
Loa Loa (eye worm) hypothetical protein 0.0054 0.0077 0.016
Onchocerca volvulus 0.0042 0.0042 0.0062
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0114 0.025 0.0581
Echinococcus granulosus mixed lineage leukemia protein mll 0.0045 0.0052 0.0065
Echinococcus multilocularis peregrin 0.0171 0.041 0.0434
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0033 0.0017 0.0013
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0033 0.0017 0.0017
Echinococcus granulosus jumonji domain containing 1A 0.0062 0.0101 0.0137
Echinococcus granulosus peregrin 0.0171 0.041 0.0586
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0057 0.0084 0.0069
Schistosoma mansoni glutaminase 0.0271 0.0697 0.1006
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0072 0.0128 0.0258
Schistosoma mansoni cpg binding protein 0.0165 0.0394 0.0564
Giardia lamblia Histone acetyltransferase GCN5 0.0195 0.048 0.0951
Echinococcus multilocularis pyruvate kinase 0.0034 0.0021 0.0022
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0858 0.2373 0.8246
Echinococcus granulosus Nuclear hormone receptor HR96 0.0054 0.0077 0.0101
Plasmodium vivax histone acetyltransferase GCN5, putative 0.022 0.055 0.3635
Mycobacterium ulcerans acyl-CoA synthetase 0.0098 0.0204 0.0584
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0114 0.025 0.0354
Echinococcus granulosus PHD finger protein rhinoceros 0.0146 0.0339 0.0483
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0098 0.0204 0.1678
Trichomonas vaginalis glucosylceramidase, putative 0.0199 0.049 0.0992
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.002 0.004
Mycobacterium ulcerans acyl-CoA synthetase 0.0098 0.0204 0.0584
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0099 0.0204 0.0655
Brugia malayi AMP-binding enzyme family protein 0.0098 0.0204 0.0469
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0099 0.0204 0.0664
Schistosoma mansoni terminal deoxycytidyl transferase 0.0058 0.009 0.0121
Schistosoma mansoni transcription factor LCR-F1 0.0626 0.171 0.2481
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0294 0.0761 0.2575
Mycobacterium tuberculosis Probable reductase 0.0311 0.0812 0.0798
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0057 0.0085 0.017
Echinococcus granulosus mothers against decapentaplegic 5 0.0049 0.0062 0.0079
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0101 0.0219
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0552 0.15 0.3625
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0054 0.0077 0.0081
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.0217 0.0306
Loa Loa (eye worm) steroid hormone receptor 0.0114 0.025 0.0581
Trichomonas vaginalis alpha-glucosidase, putative 0.0072 0.0128 0.0258
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.002 0.004
Echinococcus granulosus lysosomal alpha glucosidase 0.0324 0.0848 0.1224
Treponema pallidum NADH oxidase 0.0047 0.0058 0.0102
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0016 0.0012
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0068 0.0137
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0047 0.0058 0.0075
Brugia malayi follicle stimulating hormone receptor 0.0228 0.0575 0.1372
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0139 0.0319 0.2055
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0026 0.0041
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0123 0.0275 0.0389
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0047 0.0058 0.0151
Giardia lamblia Fructose-bisphosphate aldolase 0.1756 0.4938 1
Trichomonas vaginalis glucosylceramidase, putative 0.0287 0.0744 0.1505
Echinococcus granulosus GPCR family 2 0.0177 0.0428 0.0612
Trypanosoma brucei DNA polymerase IV, putative 0.0058 0.009 0.0508
Mycobacterium leprae conserved hypothetical protein 0.0552 0.15 0.5203
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0033 0.0017 0.0013
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0033 0.0016 0.0017
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0098 0.0204 0.0188
Plasmodium vivax CDK-related protein kinase 6, putative 0.0439 0.1177 0.7837
Echinococcus multilocularis expressed conserved protein 0.009 0.0179 0.0189
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0098 0.0204 0.0684
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0098 0.0204 0.047
Loa Loa (eye worm) isocitrate dehydrogenase 0.0033 0.0016 0.0012
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0047 0.0058 0.0151
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0041 0.0091
Schistosoma mansoni glucose transport protein 0.0103 0.0217 0.0307
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0086 0.0169 0.0328
Plasmodium vivax acetyl-CoA synthetase, putative 0.0098 0.0204 0.1315
Loa Loa (eye worm) hypothetical protein 0.0062 0.0101 0.0219
Onchocerca volvulus 0.017 0.0408 0.0843
Echinococcus multilocularis dna polymerase eta 0.0058 0.009 0.0095
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0096 0.0198 0.0399
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0074 0.0079
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0038 0.0159
Mycobacterium leprae Probable lipase LipE 0.0552 0.15 0.5203
Trypanosoma brucei glucosidase, putative 0.0072 0.0128 0.0766
Brugia malayi Probable ClpP-like protease 0.0086 0.0169 0.0386
Mycobacterium tuberculosis Probable dehydrogenase 0.0311 0.0812 0.0798
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0108 0.023 0.0534
Brugia malayi steroid hormone receptor 0.0114 0.025 0.0581
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0047 0.0058 0.0153
Plasmodium falciparum mitogen-activated protein kinase 2 0.0168 0.0403 0.3376
Echinococcus multilocularis acetylcholinesterase 0.0071 0.0124 0.0132
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0072 0.0128 0.0806
Brugia malayi Cam kinase protein 1 0.0033 0.0017 0.0013
Echinococcus granulosus smad 0.0049 0.0062 0.0079
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0066 0.0111 0.0152
Loa Loa (eye worm) hypothetical protein 0.0071 0.0124 0.0276
Brugia malayi Cytochrome P450 family protein 0.0037 0.0029 0.0044
Schistosoma mansoni hypothetical protein 0.0084 0.0162 0.0226
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0203 0.0501 0.0719
Mycobacterium ulcerans acyl-CoA synthetase 0.0098 0.0204 0.0584
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0146 0.0339 0.0485
Mycobacterium ulcerans hypothetical protein 0.0098 0.0204 0.0584
Echinococcus granulosus chromobox protein 1 0.0138 0.0316 0.045
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0045 0.0052 0.0066
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0085 0.0165 0.0149
Mycobacterium tuberculosis Probable hydrolase 0.0552 0.15 0.1486
Loa Loa (eye worm) MH2 domain-containing protein 0.0715 0.1966 0.476
Brugia malayi Intermediate filament tail domain containing protein 0.0031 0.0013 0.0004
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0236 0.0597 0.086
Leishmania major trypanothione reductase 0.0137 0.0313 0.1043
Brugia malayi Carboxylesterase family protein 0.0071 0.0124 0.0276
Loa Loa (eye worm) CXXC zinc finger family protein 0.0151 0.0354 0.0834
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.017 0.0408 0.0584
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0103 0.0217 0.023
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.017 0.0408 0.0965
Brugia malayi Pyruvate kinase, muscle isozyme 0.0034 0.0021 0.0023
Entamoeba histolytica serine/threonine protein kinase, putative 0.01 0.0208 0.0401
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.002 0.004
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0048 0.0059 0.258
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0114 0.025 0.0353
Brugia malayi Steroid receptor seven-up type 2 0.0114 0.025 0.0581
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.0461 0.0933
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0054 0.0077 0.016
Loa Loa (eye worm) hypothetical protein 0.0076 0.0141 0.0317
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0074 0.0099
Loa Loa (eye worm) hypothetical protein 0.0114 0.025 0.0581
Schistosoma mansoni lipoxygenase 0.0117 0.0256 0.0363
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0096 0.0239
Trichomonas vaginalis glutaminase, putative 0.0271 0.0697 0.1411
Trichomonas vaginalis maltase-glucoamylase, putative 0.0072 0.0128 0.0258
Schistosoma mansoni inositol transporter 0.0076 0.0141 0.0196
Giardia lamblia Pyruvate kinase 0.0034 0.0021 0.0019
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0057 0.0085 0.017
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0038 0.0159
Echinococcus granulosus microtubule associated protein 2 0.0806 0.2225 0.3229
Loa Loa (eye worm) hypothetical protein 0.0552 0.15 0.3625
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0021 0.0041
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0294 0.0761 0.2575
Echinococcus multilocularis ecdysone induced protein 78C 0.0114 0.025 0.0264
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0047 0.0058 0.0114
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0098 0.0204 0.0188
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0031 0.0011 0.0012
Brugia malayi F/Y-rich N-terminus family protein 0.0107 0.0229 0.053
Echinococcus multilocularis carboxylesterase 5A 0.0071 0.0124 0.0132
Schistosoma mansoni hypothetical protein 0.2149 0.606 0.8814
Schistosoma mansoni importin beta-1 0.0119 0.0262 0.0371
Echinococcus multilocularis lamin 0.0031 0.0013 0.0013
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0096 0.0239
Echinococcus granulosus carboxylesterase 5A 0.0071 0.0124 0.017
Echinococcus multilocularis lysine specific demethylase 5A 0.0234 0.0592 0.0626
Loa Loa (eye worm) hypothetical protein 0.0552 0.15 0.3625
Trichomonas vaginalis set domain proteins, putative 0.1672 0.4697 0.951
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0047 0.0058 0.0336
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0311 0.0812 0.2805
Loa Loa (eye worm) hypothetical protein 0.0061 0.0096 0.0206
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0098 0.0204 0.0584
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0098 0.0204 0.0286
Echinococcus multilocularis zinc finger protein 0.0084 0.0163 0.0172
Echinococcus multilocularis dna polymerase kappa 0.0058 0.009 0.0095
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0034 0.0019 0.0016
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.0461 0.0933
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0264 0.0676 0.0975
Loa Loa (eye worm) hypothetical protein 0.0047 0.0056 0.0109
Giardia lamblia PHD finger protein 15 0.0146 0.0339 0.0666
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0098 0.0204 0.0188
Plasmodium falciparum protein kinase 7 0.0293 0.0759 0.6424
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0098 0.0204 0.0188
Trichomonas vaginalis bromodomain-containing protein, putative 0.022 0.055 0.1113
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0075 0.0137 0.0145
Brugia malayi RNA binding protein 0.0062 0.0101 0.0219
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0047 0.0058 0.0153
Onchocerca volvulus 0.0552 0.15 0.3175
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0111 0.0651
Trypanosoma brucei unspecified product 0.004 0.0038 0.0159
Plasmodium falciparum histone acetyltransferase GCN5 0.0195 0.048 0.4035
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0099 0.0204 0.0655
Brugia malayi jmjC domain containing protein 0.0062 0.0101 0.0219
Loa Loa (eye worm) hypothetical protein 0.047 0.1264 0.305
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0057 0.0085 0.017
Mycobacterium ulcerans acyl-CoA synthetase 0.0098 0.0204 0.0584
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0114 0.025 0.0353
Loa Loa (eye worm) hypothetical protein 0.0098 0.0204 0.047
Schistosoma mansoni patched 1 0.0041 0.004 0.0048
Loa Loa (eye worm) hypothetical protein 0.0552 0.15 0.3625
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0048 0.0059 0.0301
Mycobacterium ulcerans beta-lactamase 0.0552 0.15 0.4717
Brugia malayi ecdysone receptor 0.0054 0.0077 0.016
Entamoeba histolytica beta-galactosidase, putative 0.0161 0.0383 0.0754
Loa Loa (eye worm) hypothetical protein 0.0583 0.1587 0.3838
Schistosoma mansoni zinc finger protein 0.0045 0.0052 0.0066
Echinococcus granulosus Protein patched homolog 1 0.0041 0.004 0.0047
Trypanosoma cruzi PAB1-binding protein , putative 0.0101 0.0212 0.0681
Brugia malayi Latrophilin receptor protein 2 0.0177 0.0428 0.1014
Entamoeba histolytica acetyltransferase, GNAT family 0.0195 0.048 0.0951
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0047 0.0058 0.0118
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0114 0.025 0.0353
Toxoplasma gondii thioredoxin reductase 0.0137 0.0313 0.2043
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0054 0.0077 0.0102
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0038 0.0159
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0114 0.025 0.0581
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0074 0.0079
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0076 0.0141 0.0149
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0559 0.1518 0.367
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.0461 0.0933
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.004 0.0037 0.0045
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0016 0.0055
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0096 0.0285
Brugia malayi nuclear receptor NHR-88 0.0114 0.025 0.0581
Echinococcus granulosus tar DNA binding protein 0.0062 0.0101 0.0136
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0137 0.0313 0.0297
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0031 0.0011 0.0012
Echinococcus multilocularis muscleblind protein 0.0583 0.1587 0.168
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.073 0.2008 0.2125
Schistosoma mansoni hypothetical protein 0.0177 0.0428 0.0613
Trypanosoma brucei hypothetical protein, conserved 0.0552 0.15 1
Echinococcus granulosus JmjC domain containing protein 4 0.0062 0.0101 0.0137
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.004 0.0037 0.0043
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0047 0.0058 0.0294
Brugia malayi beta-lactamase family protein 0.0552 0.15 0.3625
Loa Loa (eye worm) hypothetical protein 0.0552 0.15 0.3625
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0098 0.0204 0.0188
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0098 0.0204 0.0188
Leishmania major protein kinase, putative 0.0033 0.0017 0.0009
Echinococcus granulosus Niemann Pick C1 protein 0.0136 0.0312 0.0444
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0098 0.0204 0.0188
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0626 0.171 0.181
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0096 0.0101
Echinococcus granulosus Smad4 0.0049 0.0062 0.0079
Mycobacterium ulcerans esterase/lipase LipP 0.0552 0.15 0.4717
Trypanosoma cruzi DNA polymerase kappa, putative 0.0058 0.009 0.026
Schistosoma mansoni lipoxygenase 0.0042 0.0042 0.0051
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0103 0.0217 0.023
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.01 0.0208 0.0481
Mycobacterium ulcerans acyl-CoA synthetase 0.0098 0.0204 0.0584
Loa Loa (eye worm) hypothetical protein 0.0087 0.017 0.0387
Mycobacterium ulcerans acyl-CoA synthetase 0.0098 0.0204 0.0584
Schistosoma mansoni hypothetical protein 0.004 0.0035 0.0042
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0049 0.0062 0.0065
Trichomonas vaginalis DNA polymerase eta, putative 0.0058 0.009 0.018
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0376 0.0996 0.1441
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0143 0.0289
Plasmodium vivax pyruvate kinase, putative 0.0034 0.0021 0.0087
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0047 0.0058 0.0151
Brugia malayi RNA, U transporter 1 0.0337 0.0887 0.2132
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0096 0.013
Schistosoma mansoni alpha glucosidase 0.0072 0.0128 0.0177
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0076 0.0141 0.0195
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0139 0.0319 0.1053
Echinococcus multilocularis protein patched 0.0041 0.004 0.0042
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0014 0.0027
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0096 0.0196 0.0451
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0076 0.0141 0.0894
Loa Loa (eye worm) glycosyl hydrolase family 2 0.0227 0.0572 0.1365
Loa Loa (eye worm) thioredoxin reductase 0.0137 0.0313 0.0734
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0057 0.0085 0.017
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0114 0.025 0.0264
Loa Loa (eye worm) hypothetical protein 0.0119 0.0262 0.061
Onchocerca volvulus 0.0552 0.15 0.3175
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0086 0.0169 0.1383
Mycobacterium tuberculosis Probable esterase LipL 0.0552 0.15 0.1486
Echinococcus multilocularis microtubule associated protein 2 0.0806 0.2225 0.2354
Loa Loa (eye worm) hypothetical protein 0.0552 0.15 0.3625
Schistosoma mansoni hypothetical protein 0.0177 0.0428 0.0613
Schistosoma mansoni jumonji domain containing protein 0.0062 0.0101 0.0138
Plasmodium falciparum glutathione reductase 0.0047 0.0058 0.0428
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0626 0.171 0.248
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0099 0.0204 0.168
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.022 0.055 0.3635
Loa Loa (eye worm) hypothetical protein 0.0152 0.0358 0.0844
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0552 0.15 0.1486
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0066 0.0111 0.0117
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0066 0.0111 0.0151
Trichomonas vaginalis antibiotic synthetase, putative 0.0098 0.0204 0.0412
Entamoeba histolytica hypothetical protein 0.0048 0.0059 0.0097
Schistosoma mansoni pyruvate kinase 0.0034 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.006 0.0095 0.0205
Giardia lamblia NADH oxidase lateral transfer candidate 0.0047 0.0058 0.0095
Loa Loa (eye worm) jmjC domain-containing protein 0.0248 0.0632 0.1513
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0047 0.0058 0.0294
Trypanosoma cruzi polo-like protein kinase, putative 0.01 0.0208 0.067
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.0217 0.0306
Brugia malayi Niemann-Pick C1 protein precursor 0.0096 0.0195 0.0449
Brugia malayi hypothetical protein 0.0176 0.0427 0.1012
Leishmania major pyruvate kinase 0.0034 0.0021 0.0023
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0033 0.0017 0.006
Brugia malayi Bromodomain containing protein 0.0248 0.063 0.1508
Plasmodium vivax ataxin-2 like protein, putative 0.0101 0.0212 0.1367
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0057 0.0085 0.017
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0123 0.0275 0.0641
Entamoeba histolytica hypothetical protein 0.0626 0.171 0.3448
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0376 0.0996 0.2399
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0066 0.0111 0.0243
Schistosoma mansoni beta-mannosidase 0.0077 0.0143 0.0199
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0096 0.059
Schistosoma mansoni DNA polymerase eta 0.0058 0.009 0.0121
Loa Loa (eye worm) acetylcholinesterase 1 0.0071 0.0124 0.0276
Plasmodium falciparum protein kinase 6 0.0439 0.1177 1
Echinococcus granulosus SAM and MBT domain containing protein 0.0047 0.0056 0.0071
Toxoplasma gondii PHD-finger domain-containing protein 0.0146 0.0339 0.2222
Plasmodium vivax multidomain scavenger receptor, putative 0.0042 0.0042 0.0228
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0287 0.0744 0.1783
Plasmodium falciparum LCCL domain-containing protein 0.0042 0.0042 0.0291
Plasmodium falciparum phd finger protein, putative 0.0146 0.0339 0.2836
Brugia malayi MAP kinase sur-1 0.0108 0.023 0.0534
Entamoeba histolytica protein kinase, putative 0.0033 0.0017 0.0011
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0208 0.0421
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0101 0.0137
Echinococcus granulosus expressed conserved protein 0.009 0.0179 0.025
Plasmodium falciparum pyruvate kinase 0.0034 0.0021 0.0111
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.0217 0.0306
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.004 0.007
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0033 0.0016 0.0012
Brugia malayi PHD-finger family protein 0.0146 0.0339 0.0799
Onchocerca volvulus 0.0098 0.0204 0.0408
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0017 0.0017
Loa Loa (eye worm) sugar transporter 0.0103 0.0217 0.0503
Brugia malayi AMP-binding enzyme family protein 0.0098 0.0204 0.0469
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0099 0.0204 0.0585
Schistosoma mansoni lamin 0.0031 0.0013 0.0009
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0037 0.0074
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1756 0.4938 1
Echinococcus multilocularis SAM and MBT domain containing protein 0.0047 0.0056 0.0059
Brugia malayi AMP-binding enzyme family protein 0.1132 0.3157 0.766
Echinococcus multilocularis GPCR, family 2 0.0177 0.0428 0.0452
Toxoplasma gondii hypothetical protein 0.0047 0.0058 0.0336
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.004 0.0047
Brugia malayi ImpB/MucB/SamB family protein 0.0058 0.009 0.0191
Schistosoma mansoni smad 0.0049 0.0062 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0143 0.0289
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.0101 0.0219
Mycobacterium ulcerans acetyl-CoA synthetase 0.0098 0.0204 0.0584
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0047 0.0058 0.2496
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0086 0.0169 1
Schistosoma mansoni inositol transporter 0.0076 0.0141 0.0196
Schistosoma mansoni protein kinase 0.0033 0.0017 0.0015
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0376 0.0996 0.1441
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0041 0.0091
Brugia malayi hypothetical protein 0.0626 0.171 0.4137
Leishmania major 4-coumarate:coa ligase-like protein 0.0098 0.0204 0.0663
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0047 0.0058 0.0061
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0098 0.0204 0.0584
Schistosoma mansoni rab6-interacting 0.0042 0.0042 0.0051
Brugia malayi nuclear hormone receptor family member odr-7 0.0054 0.0077 0.016
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0346 0.0911 0.0897
Schistosoma mansoni RAR-like nuclear receptor 0.0114 0.025 0.0354
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.023 0.0465
Onchocerca volvulus 0.0054 0.0077 0.0137
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0108 0.023 0.0756
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.009 0.0508
Brugia malayi nuclear receptor NHR-88 0.0054 0.0077 0.016
Schistosoma mansoni hypothetical protein 0.0146 0.0339 0.0485
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0066 0.0111 0.0338
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0062 0.0101 0.0138
Schistosoma mansoni lamin 0.0031 0.0013 0.0009
Trypanosoma cruzi DNA polymerase eta, putative 0.0058 0.009 0.026
Mycobacterium tuberculosis Conserved protein 0.0552 0.15 0.1486
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0032 0.0035
Schistosoma mansoni steroid hormone receptor ad4bp 0.0114 0.025 0.0354
Echinococcus granulosus acetylcholinesterase 0.0071 0.0124 0.017
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0083 0.016 0.0315
Schistosoma mansoni thyroid hormone receptor 0.0114 0.025 0.0354
Loa Loa (eye worm) hypothetical protein 0.0264 0.0676 0.162
Mycobacterium ulcerans acyl-CoA synthetase 0.0098 0.0204 0.0584
Onchocerca volvulus 0.0151 0.0354 0.0728
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0058 0.009 0.0074
Loa Loa (eye worm) hypothetical protein 0.0058 0.009 0.0191
Toxoplasma gondii facilitative glucose transporter GT1 0.0103 0.0217 0.1405
Plasmodium falciparum ataxin-2 like protein, putative 0.0101 0.0212 0.1745
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0037 0.0074
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0026 0.0079
Brugia malayi GH02984p 0.0076 0.0141 0.0317
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0062 0.0101 0.0586
Echinococcus multilocularis polycomb protein SCMH1 0.0047 0.0056 0.0059
Leishmania major DNA polymerase eta, putative 0.0058 0.009 0.0264
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0021 0.0041
Echinococcus multilocularis mitogen activated protein kinase 3 0.0108 0.023 0.0244
Onchocerca volvulus 0.0047 0.0056 0.0092
Schistosoma mansoni nuclear hormone receptor 0.0054 0.0077 0.0102
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0033 0.0016 0.007
Mycobacterium tuberculosis Conserved hypothetical protein 0.0155 0.0364 0.0349
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0054 0.0077 0.0081
Trichomonas vaginalis antibiotic synthetase, putative 0.0098 0.0204 0.0412
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.0461 0.0933
Echinococcus granulosus lysine specific demethylase 5A 0.0248 0.0632 0.091
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0123 0.0275 0.0291
Brugia malayi Heterochromatin protein 1 0.0138 0.0316 0.0743
Echinococcus granulosus phd:f box containing protein 0.0062 0.0101 0.0137
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.009 0.0508
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0054 0.0077 0.0081
Trypanosoma cruzi hypothetical protein, conserved 0.0552 0.15 0.5122
Leishmania major phosphopantetheinyl transferase-like protein 0.0048 0.0059 0.0157
Schistosoma mansoni methyl-cpg binding protein mbd 0.005 0.0066 0.0087
Trichomonas vaginalis chromobox protein, putative 0.0138 0.0316 0.0639
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.004 0.0042
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0041 0.0041 0.0178
Schistosoma mansoni hypothetical protein 0.004 0.0035 0.0042
Echinococcus granulosus zinc finger protein 0.0084 0.0163 0.0227
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0058 0.0151
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0346 0.0911 0.0897
Trichomonas vaginalis glucosylceramidase, putative 0.0287 0.0744 0.1505
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0098 0.0204 0.0584
Trypanosoma cruzi fatty acid transporter protein-like, putative 0.1048 0.2915 1
Loa Loa (eye worm) hypothetical protein 0.0071 0.0124 0.0276
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0016 0.0017
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0114 0.025 0.0581
Trypanosoma brucei ISWI complex protein 0.0045 0.0052 0.0253
Echinococcus granulosus pyruvate kinase 0.0034 0.0021 0.0019
Brugia malayi nuclear receptor RXR 0.006 0.0095 0.0205
Echinococcus granulosus sodium:glucose cotransporter 2 0.0076 0.0141 0.0195
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0114 0.025 0.0354
Loa Loa (eye worm) hypothetical protein 0.004 0.0037 0.0064
Brugia malayi beta-lactamase 0.0552 0.15 0.3625
Echinococcus granulosus thioredoxin glutathione reductase 0.0137 0.0314 0.0447
Loa Loa (eye worm) hypothetical protein 0.0034 0.0021 0.0024
Onchocerca volvulus 0.0187 0.0458 0.095
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0098 0.0204 0.1315
Loa Loa (eye worm) hypothetical protein 0.0033 0.0017 0.0014
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.009 0.0508
Loa Loa (eye worm) beta-glucuronidase 0.0221 0.0553 0.132
Loa Loa (eye worm) hypothetical protein 0.0583 0.1587 0.3838
Leishmania major GTP-binding protein, putative 0.0067 0.0113 0.0345
Brugia malayi intermediate filament protein 0.0031 0.0013 0.0004
Plasmodium falciparum calcium-dependent protein kinase 5 0.0033 0.0017 0.0076
Trichomonas vaginalis glycoside hydrolase, putative 0.0238 0.0603 0.1221
Plasmodium vivax calcium-dependent protein kinase, putative 0.0033 0.0017 0.006
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1756 0.4938 1
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0114 0.025 0.0506
Schistosoma mansoni jumonji domain containing protein 0.0437 0.1172 0.1696
Brugia malayi Bromodomain containing protein 0.0131 0.0296 0.0694
Schistosoma mansoni glucose transport protein 0.0103 0.0217 0.0307
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0021 0.0024
Loa Loa (eye worm) hypothetical protein 0.0054 0.0077 0.016
Brugia malayi nuclear receptor NHR-67 0.0054 0.0077 0.016
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0114 0.025 0.0264
Schistosoma mansoni nuclear hormone receptor 0.0114 0.025 0.0354
Loa Loa (eye worm) nuclear receptor NHR-67 0.0054 0.0077 0.016
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0011 0.0007
Brugia malayi Sodium:solute symporter family protein 0.0076 0.0141 0.0317
Loa Loa (eye worm) hypothetical protein 0.0209 0.0519 0.1237
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0114 0.025 0.0581
Schistosoma mansoni hypothetical protein 0.0103 0.0217 0.0307
Trypanosoma brucei hypothetical protein, conserved 0.0216 0.0541 0.3543
Echinococcus granulosus Niemann Pick C1 protein 0.0096 0.0195 0.0274
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0214 0.0533 0.0766
Loa Loa (eye worm) RNA binding protein 0.0062 0.0101 0.0219
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0099 0.0204 0.0189
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0098 0.0204 0.0584
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3336 0.945 1
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.004 0.0037 0.0053
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0054 0.0078 0.0103
Trypanosoma brucei unspecified product 0.0058 0.009 0.0508
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0033 0.0016 0.0006
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0098 0.0204 0.0684
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0228 0.0575 0.1372
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0049 0.0062 0.0081
Schistosoma mansoni hypothetical protein 0.0045 0.0052 0.0067
Echinococcus multilocularis chromobox protein 1 0.0138 0.0316 0.0335
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0204 0.0504 0.0723
Echinococcus granulosus nuclear receptor nhr 48 0.0054 0.0077 0.0101
Echinococcus multilocularis Smad4 0.0049 0.0062 0.0065
Schistosoma mansoni coup transcription factor 0.0114 0.025 0.0354
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0062 0.0101 0.03
Entamoeba histolytica protein kinase, putative 0.0033 0.0017 0.0011
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0552 0.15 0.2175
Brugia malayi Bromodomain containing protein 0.0171 0.041 0.0971
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.002 0.004
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0067 0.0113 0.0705
Onchocerca volvulus 0.0053 0.0074 0.0132
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0026 0.0041
Plasmodium vivax hypothetical protein, conserved 0.0552 0.15 1
Schistosoma mansoni zinc finger protein 0.0084 0.0163 0.0228
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.002 0.004
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0203 0.0501 0.0719
Trichomonas vaginalis ran, putative 0.0067 0.0113 0.0227
Loa Loa (eye worm) hypothetical protein 0.006 0.0095 0.0205
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0552 0.15 0.3625
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0048 0.0059 0.0085
Echinococcus granulosus lipoxygenase domain containing protein 0.0042 0.0042 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.002 0.004
Loa Loa (eye worm) MBCTL1 0.0053 0.0074 0.0154
Schistosoma mansoni hypothetical protein 0.0045 0.0052 0.0066
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0054 0.0077 0.0081
Brugia malayi MH2 domain containing protein 0.0049 0.0062 0.0124
Leishmania major hypothetical protein, conserved 0.0216 0.0541 0.184
Brugia malayi hypothetical protein 0.0054 0.0077 0.016
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.0101 0.0219
Loa Loa (eye worm) hypothetical protein 0.0177 0.0428 0.1014
Entamoeba histolytica hypothetical protein 0.0626 0.171 0.3448
Loa Loa (eye worm) hypothetical protein 0.0146 0.0339 0.0799
Plasmodium vivax thioredoxin reductase, putative 0.0137 0.0313 0.2043
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.0461 0.0933
Schistosoma mansoni chromobox protein 0.0138 0.0316 0.0451
Onchocerca volvulus 0.1672 0.4697 1
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0048 0.0059 0.0344
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0076 0.0141 0.0149
Loa Loa (eye worm) hypothetical protein 0.0114 0.025 0.0581
Echinococcus granulosus pyruvate kinase 0.0034 0.0021 0.0019
Echinococcus granulosus lipoxygenase domain containing protein 0.0042 0.0042 0.005
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0077 0.0142 0.0196
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.073 0.2008 0.2915
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1756 0.4938 1
Trichomonas vaginalis CMGC family protein kinase 0.0108 0.023 0.0465
Echinococcus multilocularis acetylcholinesterase 0.0071 0.0124 0.0132
Echinococcus multilocularis isocitrate dehydrogenase 0.0033 0.0016 0.0017
Loa Loa (eye worm) hypothetical protein 0.0062 0.01 0.0216
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0086 0.0169 0.0236
Brugia malayi beta-lactamase family protein 0.0552 0.15 0.3625
Plasmodium vivax hypothetical protein, conserved 0.0146 0.0339 0.2222
Schistosoma mansoni alpha-glucosidase 0.0279 0.0719 0.1037
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0204 0.0504 0.0533
Brugia malayi Nuclear hormone receptor-like 1 0.006 0.0095 0.0205
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.01 0.0208 0.0221
Schistosoma mansoni loxhd1 0.0042 0.0042 0.0051
Echinococcus granulosus importin subunit beta 1 0.0119 0.0262 0.037
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0324 0.0848 0.2037
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1756 0.4938 1
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.005 0.0066 0.018
Brugia malayi nuclear hormone receptor 0.0114 0.025 0.0581
Schistosoma mansoni hypothetical protein 0.0177 0.0428 0.0613
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0045 0.0052 0.0055
Brugia malayi hypothetical protein 0.0054 0.0077 0.016
Echinococcus granulosus thyroid hormone receptor alpha 0.0054 0.0077 0.0101
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0033 0.0016 0.0012
Brugia malayi Doublecortin family protein 0.0042 0.0042 0.0075
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0858 0.2373 0.2361
Schistosoma mansoni hypothetical protein 0.2434 0.6874 1
Plasmodium falciparum calcium-dependent protein kinase 3 0.0033 0.0017 0.0076
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0072 0.0128 0.0258
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0177 0.0428 0.0612
Echinococcus granulosus peptidase Clp S14 family 0.0057 0.0084 0.0112
Schistosoma mansoni bromodomain containing protein 0.0039 0.0034 0.004
Brugia malayi hypothetical protein 0.0065 0.0109 0.0239
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0048 0.0059 0.0343
Brugia malayi hypothetical protein 0.047 0.1264 0.305
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0208 0.0421
Mycobacterium ulcerans DNA polymerase IV 0.0058 0.009 0.022
Echinococcus granulosus beta LACTamase domain containing family member 0.0552 0.15 0.2174
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0177 0.0428 0.0452
Echinococcus granulosus lysine specific demethylase 6a 0.0062 0.0101 0.0137
Trichomonas vaginalis D-aminoacylase, putative 0.0552 0.15 0.3037
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0033 0.0017 0.0013
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0093 0.0188 0.0264
Schistosoma mansoni nuclear receptor 0.0054 0.0077 0.0102
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0016 0.0006
Trypanosoma cruzi trypanothione reductase, putative 0.0137 0.0313 0.1029
Trypanosoma cruzi importin beta-1 subunit, putative 0.0096 0.0198 0.0632
Plasmodium vivax proline--tRNA ligase, putative 0.0036 0.0026 0.0121
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0072 0.0128 0.0237
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0066 0.0111 0.0202
Brugia malayi Sugar transporter family protein 0.0103 0.0217 0.0502
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0033 0.0017 0.0013
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0114 0.025 0.0264
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0099 0.0204 0.0392
Brugia malayi glutaminase DH11.1 0.0271 0.0697 0.167
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0054 0.0077 0.016
Loa Loa (eye worm) hypothetical protein 0.0087 0.017 0.0387
Loa Loa (eye worm) acetyltransferase 0.073 0.2008 0.4863
Loa Loa (eye worm) MH1 domain-containing protein 0.0049 0.0062 0.0124
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0047 0.0056 0.0092
Schistosoma mansoni smad1 5 8 and 0.0049 0.0062 0.0081
Loa Loa (eye worm) glutaminase 0.0271 0.0697 0.1671
Brugia malayi mbt repeat family protein 0.0047 0.0056 0.0109
Brugia malayi Isocitrate dehydrogenase 0.0033 0.0016 0.0012
Echinococcus granulosus high affinity choline transporter 1 0.0076 0.0141 0.0195
Loa Loa (eye worm) hypothetical protein 0.0054 0.0077 0.016
Schistosoma mansoni glucose transport protein 0.0103 0.0217 0.0307
Brugia malayi latrophilin 2 splice variant baaae 0.0382 0.1013 0.244
Trypanosoma cruzi DNA polymerase kappa, putative 0.0058 0.009 0.026
Echinococcus multilocularis snurportin 1 0.1267 0.3541 0.3747
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0123 0.0275 0.091
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0099 0.0204 1
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0098 0.0204 0.0188
Schistosoma mansoni ran 0.0067 0.0113 0.0155
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0114 0.025 0.0581
Plasmodium falciparum glutathione reductase 0.0137 0.0313 0.2607
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0047 0.0058 0.0118
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0098 0.0204 0.0684
Schistosoma mansoni nuclear hormone receptor 0.0054 0.0077 0.0102
Plasmodium vivax importin-beta 2, putative 0.0119 0.0262 0.1702
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0114 0.025 0.0581
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0552 0.15 0.1486
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0099 0.0204 0.0287
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0098 0.0204 0.0391
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0098 0.0204 0.0654
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0031 0.0011 0.0021
Echinococcus granulosus fetal alzheimer antigen falz 0.0075 0.0137 0.0189
Brugia malayi ecdysteroid receptor 0.0114 0.025 0.0581
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0054 0.0077 0.0137
Onchocerca volvulus Alhambra homolog 0.0146 0.0339 0.0697
Schistosoma mansoni alpha-glucosidase 0.0279 0.0719 0.1037
Trypanosoma cruzi hypothetical protein, conserved 0.0552 0.15 0.5122
Toxoplasma gondii ABC1 family protein 0.0552 0.15 1
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0098 0.0204 0.0584
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.0101 0.0219
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.006 0.0095 0.0129
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0098 0.0204 0.1315
Plasmodium falciparum hexose transporter 0.0103 0.0217 0.1793
Loa Loa (eye worm) hypothetical protein 0.0062 0.0101 0.0219
Schistosoma mansoni retinoic acid receptor RXR 0.0114 0.025 0.0354
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.009 0.0508
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0114 0.025 0.0581
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0037 0.0074
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0054 0.0077 0.0101
Loa Loa (eye worm) CHromoDomain protein family member 0.0037 0.0028 0.0041
Brugia malayi AMP-binding enzyme family protein 0.0098 0.0204 0.0469
Plasmodium falciparum proline--tRNA ligase 0.0036 0.0026 0.0154
Plasmodium vivax hexose transporter 0.0103 0.0217 0.1405
Loa Loa (eye worm) hypothetical protein 0.0054 0.0077 0.016
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.009 0.0508
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0047 0.0056 0.0072
Loa Loa (eye worm) hypothetical protein 0.0098 0.0204 0.047
Trichomonas vaginalis sucrase-isomaltase, putative 0.0072 0.0128 0.0258
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0014 0.0027
Brugia malayi isocitrate dehydrogenase 0.0033 0.0016 0.0012
Brugia malayi AMP-binding enzyme family protein 0.0098 0.0204 0.0469
Trypanosoma cruzi PAB1-binding protein , putative 0.0101 0.0212 0.0681
Echinococcus granulosus Nuclear hormone receptor HR96 0.0054 0.0077 0.0101
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0074 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.002 0.004
Plasmodium falciparum JmjC domain-containing protein, putative 0.0062 0.0101 0.0798
Loa Loa (eye worm) hypothetical protein 0.0176 0.0427 0.1012
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.004 0.0037 0.0053
Onchocerca volvulus 0.0236 0.0597 0.1247
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0067 0.0113 0.0705
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0033 0.0016 0.0014
Echinococcus multilocularis cpg binding protein 0.0165 0.0394 0.0417
Echinococcus granulosus TGF beta signal transducer SmadC 0.0049 0.0062 0.0079
Brugia malayi hypothetical protein 0.0101 0.0212 0.0489
Trypanosoma cruzi ISWI complex protein 0.0045 0.0052 0.013
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0098 0.0204 0.1277
Echinococcus multilocularis long chain fatty acid transport protein 4 0.1048 0.2915 0.3085
Loa Loa (eye worm) hypothetical protein 0.0113 0.0246 0.0573
Plasmodium falciparum ataxin-2 like protein, putative 0.0101 0.0212 0.1745
Loa Loa (eye worm) PHD-finger family protein 0.0146 0.0339 0.0799
Trichomonas vaginalis importin beta-1, putative 0.0096 0.0198 0.0399
Echinococcus granulosus serine:threonine protein kinase PLK1 0.01 0.0208 0.0293
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0026 0.004
Brugia malayi MH2 domain containing protein 0.0049 0.0062 0.0124
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.01 0.0208 0.0679
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0048 0.0059 0.0122
Loa Loa (eye worm) hypothetical protein 0.0077 0.0143 0.0322
Onchocerca volvulus 0.0552 0.15 0.3175
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0067 0.0113 0.0119
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0114 0.025 0.0264
Trichomonas vaginalis alpha-glucosidase, putative 0.0072 0.0128 0.0258
Loa Loa (eye worm) hypothetical protein 0.0042 0.0042 0.0075
Plasmodium falciparum importin beta, putative 0.0119 0.0262 0.2171
Schistosoma mansoni sodium/solute symporter 0.0076 0.0141 0.0196
Echinococcus granulosus neutral alpha glucosidase AB 0.0072 0.0128 0.0176
Schistosoma mansoni intermediate filament proteins 0.0031 0.0013 0.0009
Echinococcus multilocularis Niemann Pick C1 protein 0.0096 0.0195 0.0207
Schistosoma mansoni protein kinase 0.0033 0.0017 0.0015
Trypanosoma cruzi hypothetical protein, conserved 0.0216 0.0541 0.1815
Echinococcus multilocularis neutral alpha glucosidase AB 0.0072 0.0128 0.0135
Trypanosoma brucei DNA polymerase eta, putative 0.0058 0.009 0.0508
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0038 0.0032 0.0064
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0026 0.004
Toxoplasma gondii pyruvate kinase PyK1 0.0034 0.0021 0.0087
Plasmodium vivax hypothetical protein, conserved 0.0057 0.0085 0.0519
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.004 0.0037 0.0043
Echinococcus multilocularis methyl CpG binding domain protein 2 0.005 0.0066 0.007
Mycobacterium ulcerans hypothetical protein 0.0155 0.0364 0.1096
Schistosoma mansoni hypothetical protein 0.2434 0.6874 1
Echinococcus granulosus survival motor neuron protein 1 0.047 0.1264 0.183
Loa Loa (eye worm) hypothetical protein 0.005 0.0066 0.0134
Schistosoma mansoni serine/threonine protein kinase 0.01 0.0208 0.0294
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0106 0.0226 0.0318
Loa Loa (eye worm) hypothetical protein 0.0114 0.025 0.0581
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0096 0.008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0114 0.025 0.0581
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0108 0.023 0.0746
Loa Loa (eye worm) hypothetical protein 0.0054 0.0077 0.016
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1756 0.4938 1
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0067 0.0113 0.0248
Trichomonas vaginalis glucosylceramidase, putative 0.0287 0.0744 0.1505
Schistosoma mansoni serine/threonine protein kinase 0.0033 0.0017 0.0015
Loa Loa (eye worm) intermediate filament protein 0.0031 0.0013 0.0004
Echinococcus granulosus histone lysine methyltransferase setb 0.0264 0.0676 0.0974
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0117 0.0256 0.0362
Brugia malayi jmjC domain containing protein 0.0535 0.1452 0.3508
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0264 0.0676 0.0716
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0103 0.0217 0.023
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1756 0.4938 1
Echinococcus multilocularis lipoxygenase domain containing protein 0.0042 0.0042 0.0044
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0114 0.025 0.0264
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0858 0.2373 0.75
Schistosoma mansoni Smad4 0.0049 0.0062 0.0081
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0047 0.0058 0.0042
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0114 0.025 0.0353
Echinococcus multilocularis dnaJ subfamily B 0.2149 0.606 0.6412
Brugia malayi Pyruvate kinase, M2 isozyme 0.0034 0.0021 0.0023
Trichomonas vaginalis glucosylceramidase, putative 0.0287 0.0744 0.1505
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0017 0.0017
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0058 0.009 0.0095
Echinococcus multilocularis solute carrier family 5 0.0076 0.0141 0.0149
Echinococcus multilocularis muscleblind protein 1 0.0583 0.1587 0.168
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.009 0.0508
Trypanosoma cruzi DNA polymerase kappa, putative 0.0058 0.009 0.026
Mycobacterium ulcerans DNA polymerase IV 0.0058 0.009 0.022
Echinococcus multilocularis thyroid hormone receptor alpha 0.0114 0.025 0.0264
Loa Loa (eye worm) heterochromatin protein 1 0.0138 0.0316 0.0743
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0099 0.0204 0.0216
Brugia malayi hypothetical protein 0.0042 0.0042 0.0075
Plasmodium vivax glutathione reductase, putative 0.0137 0.0313 0.2043
Entamoeba histolytica hypothetical protein 0.0096 0.0198 0.0378
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0177 0.0428 0.0452
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0058 0.009 0.018
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0535 0.1452 0.1536
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0108 0.023 0.1456
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0086 0.0169 0.0179
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0077 0.0142 0.015
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0047 0.0058 0.0428
Trypanosoma brucei polo-like protein kinase 0.01 0.0208 0.1308
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0017 0.0017
Schistosoma mansoni hypothetical protein 0.004 0.0035 0.0042
Echinococcus multilocularis tumor protein p63 0.0363 0.0959 0.1014
Trypanosoma brucei DNA polymerase IV, putative 0.0058 0.009 0.0508
Trichomonas vaginalis D-aminoacylase, putative 0.0552 0.15 0.3037
Brugia malayi nuclear hormone receptor family member nhr-6 0.0054 0.0077 0.016
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0057 0.0085 0.017
Echinococcus granulosus solute carrier family 5 0.0076 0.0141 0.0195
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0108 0.023 0.0756
Loa Loa (eye worm) hypothetical protein 0.0114 0.025 0.0581
Trypanosoma brucei pyruvate kinase 1 0.0034 0.0021 0.0044
Leishmania major fatty acid transporter protein-like protein 0.1034 0.2876 1
Echinococcus multilocularis survival motor neuron protein 1 0.047 0.1264 0.1337
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0098 0.0204 0.0654
Brugia malayi jmjC domain containing protein 0.0062 0.0101 0.0219
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0101 0.0137
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0045 0.0052 0.0055
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0047 0.0058 0.0151
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0032 0.0033
Echinococcus granulosus methyl CpG binding domain protein 2 0.005 0.0066 0.0086
Trypanosoma cruzi polo-like protein kinase, putative 0.01 0.0208 0.067
Trypanosoma cruzi ISWI complex protein 0.0045 0.0052 0.013
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.004 0.0037 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0079 0.0159
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0376 0.0996 0.1054
Trichomonas vaginalis CAMK family protein kinase 0.0033 0.0017 0.0032
Plasmodium vivax SET domain containing protein 0.0036 0.0025 0.0114
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0108 0.023 0.0746
Echinococcus multilocularis lysosomal alpha glucosidase 0.0324 0.0848 0.0897
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0098 0.0204 0.0188
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.009 0.0508
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0098 0.0204 0.0469
Echinococcus multilocularis lysine specific demethylase 6a 0.0062 0.0101 0.0107
Brugia malayi exodeoxyribonuclease III family protein 0.0099 0.0204 0.047
Brugia malayi Glycosyl hydrolases family 2, sugar binding domain containing protein 0.0227 0.0572 0.1365
Schistosoma mansoni hypothetical protein 0.0042 0.0042 0.0051
Trichomonas vaginalis chromobox protein, putative 0.0083 0.016 0.0323
Schistosoma mansoni retinoid-x-receptor (RXR) 0.006 0.0095 0.0129
Brugia malayi jmjC domain containing protein 0.0248 0.0632 0.1513
Loa Loa (eye worm) hypothetical protein 0.0054 0.0077 0.016
Onchocerca volvulus 0.0176 0.0427 0.0884
Schistosoma mansoni phosphatidylserine receptor 0.0062 0.0101 0.0138
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0096 0.013
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.022 0.055 0.1113
Schistosoma mansoni phd/f-box containing protein 0.0062 0.0101 0.0138
Loa Loa (eye worm) hypothetical protein 0.0114 0.025 0.0581
Brugia malayi acetyltransferase, GNAT family protein 0.073 0.2008 0.4863
Brugia malayi Nuclear hormone receptor E75 0.0054 0.0077 0.016
Echinococcus multilocularis Niemann Pick C1 protein 0.0136 0.0312 0.0331
Brugia malayi hypothetical protein 0.0042 0.0042 0.0075
Schistosoma mansoni eyes absent homolog 0.0087 0.017 0.0238
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0208 0.0421
Schistosoma mansoni zinc finger protein 0.0054 0.0077 0.0102
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0045 0.0052 0.0055
Loa Loa (eye worm) hypothetical protein 0.0096 0.0195 0.0449
Brugia malayi Glycosyl hydrolases family 31 protein 0.0072 0.0128 0.0285
Toxoplasma gondii LsmAD domain-containing protein 0.0101 0.0212 0.1367
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0552 0.15 0.2175
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0014 0.0027
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0021 0.0017
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0097 0.02 0.0281
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0037 0.008
Brugia malayi nuclear hormone receptor 0.0054 0.0077 0.016
Brugia malayi AMP-binding enzyme family protein 0.0098 0.0204 0.0469
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0114 0.025 0.0353
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0048 0.0059 0.0344
Schistosoma mansoni hypothetical protein 0.004 0.0035 0.0042
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0311 0.0812 0.0798
Onchocerca volvulus 0.0098 0.0204 0.0408
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0264 0.0676 0.0975
Toxoplasma gondii PHD-finger domain-containing protein 0.0048 0.0059 0.0343
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0048 0.0059 0.0301
Trypanosoma brucei DNA polymerase kappa, putative 0.0058 0.009 0.0508
Brugia malayi jmjC domain containing protein 0.0062 0.0101 0.0219
Loa Loa (eye worm) hypothetical protein 0.006 0.0095 0.0205
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0062 0.0101 0.0626
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0021 0.0023
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0058 0.009 0.012
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0099 0.0204 0.047
Treponema pallidum exodeoxyribonuclease (exoA) 0.0099 0.0204 0.0398
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0101 0.0219
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0047 0.0058 0.0151
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0045 0.0052 0.0065
Schistosoma mansoni ran 0.0067 0.0113 0.0155
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0037 0.0028 0.0029
Trypanosoma brucei trypanothione reductase 0.0137 0.0313 0.2009
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0039 0.0079
Echinococcus granulosus muscleblind protein 0.0583 0.1587 0.2301
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0056 0.0072
Mycobacterium leprae possible long-chain acyl-CoA synthase 0.1034 0.2876 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0123 0.0275 0.081
Plasmodium falciparum calcium-dependent protein kinase 4 0.0033 0.0017 0.0076
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0098 0.0204 0.0216
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0114 0.025 0.0581
Schistosoma mansoni survival motor neuron protein 0.0096 0.0196 0.0276
Trichomonas vaginalis beta-mannosidase, putative 0.0077 0.0143 0.0289
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0346 0.0911 0.3151
Loa Loa (eye worm) glutathione reductase 0.0137 0.0313 0.0734
Schistosoma mansoni cpg binding protein 0.0151 0.0354 0.0505
Echinococcus multilocularis RUN 0.0042 0.0042 0.0044
Giardia lamblia DINP protein human, muc B family 0.0058 0.009 0.0159
Trichomonas vaginalis D-aminoacylase, putative 0.0552 0.15 0.3037
Trypanosoma brucei hypothetical protein, conserved 0.0048 0.0059 0.0303
Echinococcus granulosus histone acetyltransferase KAT2B 0.022 0.055 0.079
Loa Loa (eye worm) hypothetical protein 0.0054 0.0077 0.016
Trypanosoma brucei unspecified product 0.004 0.0038 0.0159
Echinococcus granulosus geminin 0.2434 0.6874 1
Brugia malayi TAR-binding protein 0.0062 0.0101 0.0219
Loa Loa (eye worm) hypothetical protein 0.0138 0.0317 0.0745
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0376 0.0996 0.144
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0047 0.0058 0.0151
Onchocerca volvulus Bile acid receptor homolog 0.0114 0.025 0.0506
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.006 0.0095 0.0101
Echinococcus multilocularis protein dispatched 1 0.0047 0.0056 0.006
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0098 0.0204 0.0684
Trichomonas vaginalis helicase, putative 0.0034 0.002 0.004
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0114 0.025 0.0581
Echinococcus granulosus dnaJ subfamily B 0.2149 0.606 0.8813
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0048 0.0059 0.0344
Loa Loa (eye worm) hypothetical protein 0.0054 0.0077 0.016
Plasmodium falciparum thioredoxin reductase 0.0047 0.0058 0.0428
Leishmania major hypothetical protein, conserved 0.0552 0.15 0.5192
Loa Loa (eye worm) beta-lactamase 0.0552 0.15 0.3625
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0139 0.0319 0.1067
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0114 0.025 0.0264
Echinococcus multilocularis chromobox protein 1 0.0138 0.0316 0.0335
Treponema pallidum fructose-bisphosphate aldolase 0.1756 0.4938 1
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0098 0.0204 0.1277
Mycobacterium tuberculosis Conserved protein 0.0552 0.15 0.1486
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0114 0.025 0.0354
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0096 0.0198 0.0399
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0048 0.0059 0.0439
Echinococcus multilocularis mitogen activated protein kinase 0.0108 0.023 0.0244
Schistosoma mansoni smad1 5 8 and 0.0049 0.0062 0.0081
Brugia malayi Thioredoxin reductase 0.0137 0.0313 0.0734
Leishmania major alpha glucosidase II subunit, putative 0.0072 0.0128 0.0398
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0114 0.025 0.0581
Loa Loa (eye worm) hypothetical protein 0.0031 0.0013 0.0004
Echinococcus granulosus FTZ F1 alpha 0.0114 0.025 0.0353
Schistosoma mansoni jumonji/arid domain-containing protein 0.0248 0.0632 0.0911
Plasmodium vivax SET domain protein, putative 0.0214 0.0533 0.3517
Schistosoma mansoni protein kinase 0.0033 0.0017 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0114 0.025 0.0581
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0033 0.0017 0.006
Echinococcus multilocularis smad 0.0049 0.0062 0.0065
Loa Loa (eye worm) hypothetical protein 0.0552 0.15 0.3625
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0072 0.0128 0.0237
Brugia malayi Glycosyl hydrolases family 31 protein 0.0324 0.0848 0.2037
Echinococcus granulosus long chain fatty acid transport protein 4 0.1048 0.2915 0.4234
Onchocerca volvulus 0.0114 0.025 0.0506
Loa Loa (eye worm) hypothetical protein 0.0041 0.004 0.007
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0037 0.0028 0.0031
Trypanosoma brucei importin beta-1 subunit, putative 0.0119 0.0262 0.1666
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0099 0.0204 0.0392
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0014 0.0027
Brugia malayi orphan nuclear receptor NR2E1 0.0054 0.0077 0.016
Echinococcus granulosus dna polymerase eta 0.0058 0.009 0.012
Plasmodium vivax JmjC domain containing protein 0.0062 0.0101 0.0626
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0057 0.0084 0.0069
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0062 0.0101 0.03
Loa Loa (eye worm) hypothetical protein 0.0039 0.0034 0.0056
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0033 0.0017 0.0014
Mycobacterium ulcerans acyl-CoA synthetase 0.0098 0.0204 0.0584
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.002 0.004
Brugia malayi Beta-glucuronidase precursor 0.0221 0.0553 0.132
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0086 0.0169 0.1084
Brugia malayi Smad1 0.0049 0.0062 0.0124
Trichomonas vaginalis esterase, putative 0.0552 0.15 0.3037
Giardia lamblia Kinase, CMGC MAPK 0.0108 0.023 0.0445
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0047 0.0058 0.0118
Echinococcus multilocularis phd:f box containing protein 0.0062 0.0101 0.0107
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1756 0.4938 1
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0021 0.0024
Echinococcus multilocularis beta LACTamase domain containing family member 0.0552 0.15 0.1587
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0096 0.0195 0.0374
Plasmodium falciparum thioredoxin reductase 0.0137 0.0313 0.2607
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0114 0.025 0.0581
Loa Loa (eye worm) latrophilin receptor protein 2 0.0177 0.0428 0.1014
Echinococcus multilocularis lysosomal alpha glucosidase 0.0324 0.0848 0.0897
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.002 0.004
Giardia lamblia Kinase, PLK 0.01 0.0208 0.0401
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0098 0.0204 0.0684
Schistosoma mansoni nuclear receptor nhr-48 0.0054 0.0077 0.0102
Brugia malayi AF-10 protein 0.0048 0.0059 0.0116
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0016 0.0017
Loa Loa (eye worm) hypothetical protein 0.0144 0.0333 0.0783
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0021 0.0024
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0114 0.025 0.0581
Loa Loa (eye worm) DR-78 0.0054 0.0077 0.016
Onchocerca volvulus 0.0098 0.0204 0.0408
Loa Loa (eye worm) nuclear hormone receptor 0.0054 0.0077 0.016
Plasmodium falciparum calcium-dependent protein kinase 1 0.0033 0.0017 0.0076
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1469 0.4118 1
Loa Loa (eye worm) hypothetical protein 0.0382 0.1013 0.2441
Loa Loa (eye worm) hypothetical protein 0.0265 0.0681 0.1631
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0552 0.15 0.4717
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1756 0.4938 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0114 0.025 0.0581
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0101 0.0219
Loa Loa (eye worm) AMP-binding enzyme family protein 0.1132 0.3157 0.766
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0559 0.1518 0.367
Onchocerca volvulus Glucosylceramidase homolog 0.0189 0.0461 0.0958
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0114 0.025 0.0581
Trypanosoma brucei importin beta-1 subunit, putative 0.0119 0.0262 0.1666
Loa Loa (eye worm) hypothetical protein 0.0101 0.0212 0.0489
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0098 0.0204 0.0188
Entamoeba histolytica acyl-CoA synthetase, putative 0.0098 0.0204 0.0391
Toxoplasma gondii NADPH-glutathione reductase 0.0047 0.0058 0.0336
Onchocerca volvulus 0.0061 0.0096 0.0177
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0057 0.0085 0.017
Echinococcus granulosus acetylcholinesterase 0.0071 0.0124 0.017
Schistosoma mansoni high-affinity choline transporter 0.0076 0.0141 0.0196
Trichomonas vaginalis mercuric reductase, putative 0.0047 0.0058 0.0116
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0047 0.0058 0.0294
Brugia malayi nuclear receptor RXR 0.0054 0.0077 0.016
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0294 0.0761 0.5027
Echinococcus granulosus mitogen activated protein kinase 0.0108 0.023 0.0325
Schistosoma mansoni nuclear receptor 0.0054 0.0077 0.0102
Loa Loa (eye worm) glutaminase 2 0.0271 0.0697 0.1671
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0096 0.0129
Schistosoma mansoni jumonji/arid domain-containing protein 0.0248 0.0632 0.0911
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0115 0.0251 0.0584
Trichomonas vaginalis glutathione reductase, putative 0.0047 0.0058 0.0116
Entamoeba histolytica hypothetical protein 0.0626 0.171 0.3448
Schistosoma mansoni thyroid hormone receptor 0.0114 0.025 0.0354
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0214 0.0533 0.3517
Brugia malayi hypothetical protein 0.0087 0.017 0.0387
Brugia malayi mbt repeat family protein 0.0047 0.0056 0.0109
Schistosoma mansoni polycystin 1-related 0.0042 0.0042 0.0051
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0016 0.0017
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0376 0.0996 0.144
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0067 0.0113 0.0341
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0033 0.0017 0.006
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0017 0.0017
Loa Loa (eye worm) oxidoreductase 0.0098 0.0204 0.047
Echinococcus granulosus jumonji domain containing protein 0.0203 0.0502 0.0721
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0114 0.025 0.0581
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0047 0.0058 0.0153
Loa Loa (eye worm) bromodomain containing protein 0.007 0.0122 0.0271
Echinococcus granulosus intermediate filament protein 0.0031 0.0013 0.0008
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0203 0.0501 0.0531
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0054 0.0077 0.0101
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0016 0.0055
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0123 0.0275 0.0259
Brugia malayi Nuclear hormone receptor-like 1 0.006 0.0095 0.0205
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0067 0.0113 0.0207
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0114 0.025 0.0581
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.004 0.0079
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0128 0.0393
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0098 0.0204 0.0188
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0067 0.0113 0.0248
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0056 0.0072
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0086 0.0169 0.1084
Echinococcus granulosus chromobox protein 1 0.0138 0.0316 0.045
Loa Loa (eye worm) doublecortin family protein 0.0042 0.0042 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0014 0.0027
Brugia malayi Pre-SET motif family protein 0.1469 0.4118 1
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0208 0.0421
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0066 0.0111 0.0243
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0054 0.0077 0.0137
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0033 0.0017 0.006
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0311 0.0812 0.0798
Echinococcus granulosus Polycystic kidney disease protein 0.0042 0.0042 0.005
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0376 0.0996 0.1441
Schistosoma mansoni hypothetical protein 0.0382 0.1013 0.1466
Leishmania major pantothenate kinase subunit, putative 0.0034 0.0019 0.0016
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0033 0.0017 0.0014
Entamoeba histolytica hypothetical protein 0.0626 0.171 0.3448
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0311 0.0812 0.0798
Brugia malayi CHD4 protein 0.0037 0.0028 0.0041
Trichomonas vaginalis glucosylceramidase, putative 0.0287 0.0744 0.1505
Schistosoma mansoni acetyl-CoA synthetase 0.0098 0.0204 0.0287
Onchocerca volvulus 0.0076 0.0141 0.0274
Leishmania major mitochondrial DNA polymerase beta 0.0294 0.0761 0.261
Echinococcus multilocularis musashi 0.0031 0.0013 0.0013
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0033 0.0016 0.0055
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0054 0.0077 0.0081
Schistosoma mansoni hypothetical protein 0.0061 0.0097 0.0131
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0048 0.0059 0.0122
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0048 0.0059 0.0043
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0111 0.0333
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.004 0.0037 0.0045
Loa Loa (eye worm) hypothetical protein 0.0098 0.0204 0.047
Onchocerca volvulus 0.0098 0.0204 0.0408
Toxoplasma gondii exonuclease III APE 0.0099 0.0204 0.1316
Trypanosoma brucei PAB1-binding protein , putative 0.0101 0.0212 0.133
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0021 0.0017
Loa Loa (eye worm) hypothetical protein 0.0054 0.0077 0.016
Mycobacterium tuberculosis Conserved hypothetical protein 0.0058 0.009 0.0074
Loa Loa (eye worm) hypothetical protein 0.0076 0.0141 0.0317
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0047 0.0058 0.0151
Brugia malayi ImpB/MucB/SamB family protein 0.0058 0.009 0.0191
Schistosoma mansoni microtubule-associated protein tau 0.0806 0.2225 0.323
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0208 0.0421
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0037 0.008
Loa Loa (eye worm) hypothetical protein 0.0054 0.0077 0.016
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0062 0.0101 0.0626
Echinococcus granulosus ubiquitin specific protease 41 0.004 0.0037 0.0043
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0011 0.0007
Schistosoma mansoni ap endonuclease 0.0099 0.0204 0.0288
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0123 0.0275 0.081

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.