Detailed information for compound 59559

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 316.353 | Formula: C13H24N4O5
  • H donors: 4 H acceptors: 5 LogP: -1.01 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(CC(N(C(=O)C)O)C(=O)NC(C(=O)NCC(=O)N)C)C
  • InChi: 1S/C13H24N4O5/c1-7(2)5-10(17(22)9(4)18)13(21)16-8(3)12(20)15-6-11(14)19/h7-8,10,22H,5-6H2,1-4H3,(H2,14,19)(H,15,20)(H,16,21)
  • InChiKey: XXZXWLOQXCADNG-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0127 0.0239 0.0276
Plasmodium falciparum protein kinase 5 0.0133 0.026 0.0252
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0223 0.0598 0.0677
Echinococcus granulosus c src tyrosine kinase 0.0145 0.0307 0.0339
Plasmodium falciparum casein kinase 2, alpha subunit 0.0114 0.0191 0.0182
Plasmodium falciparum ABC1 family, putative 0.0098 0.0132 0.0123
Brugia malayi Protein kinase domain containing protein 0.0609 0.2036 0.2349
Trypanosoma brucei Casein kinase II 0.0114 0.0191 0.0261
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0223 0.0598 0.0677
Brugia malayi Variant SH3 domain containing protein 0.0097 0.0128 0.0132
Echinococcus granulosus tyrosine protein kinase Src42A 0.0232 0.0632 0.0716
Trypanosoma cruzi casein kinase, putative 0.0198 0.0504 0.0709
Trypanosoma cruzi p21-activated kinase 3, putative 0.0069 0.0023 0.0021
Entamoeba histolytica protein kinase, putative 0.0135 0.0269 0.2244
Leishmania major mitogen-activated protein kinase kinase 2 0.0109 0.0172 0.0234
Loa Loa (eye worm) TK/DDR protein kinase 0.0279 0.0805 0.0933
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.0152 0.1323
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0364 0.1123 0.1288
Trypanosoma cruzi cdc2-related kinase 1 0.0133 0.026 0.036
Echinococcus granulosus tyrosine protein kinase Lyn 0.028 0.0811 0.0924
Entamoeba histolytica p21-activated kinase 0.0109 0.0172 0.1409
Schistosoma mansoni serine/threonine protein kinase 0.0136 0.0273 0.0314
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0101 0.014 0.0145
Echinococcus granulosus mitogen activated protein kinase 11 0.1937 0.6992 0.8104
Brugia malayi MAP kinase sur-1 0.0098 0.0131 0.0136
Echinococcus granulosus titin 0.0085 0.0081 0.0077
Loa Loa (eye worm) TK/FER protein kinase 0.0105 0.0156 0.0179
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0235 0.0642 0.0728
Schistosoma mansoni serine/threonine protein kinase 0.0085 0.0083 0.0094
Trichomonas vaginalis AGC family protein kinase 0.0118 0.0204 0.1808
Echinococcus multilocularis nmda type glutamate receptor 0.0068 0.0017 0.0002
Schistosoma mansoni serine/threonine kinase 0.023 0.0623 0.072
Entamoeba histolytica protein kinase, putative 0.0115 0.0194 0.1597
Schistosoma mansoni serine/threonine protein kinase 0.0104 0.0152 0.0174
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0068 0.0017 0.0002
Leishmania major protein kinase, putative 0.0159 0.0359 0.0501
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0171 0.1502
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0068 0.0017 0.0002
Echinococcus multilocularis protein arginine N methyltransferase 5 0.0153 0.0336 0.0372
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0167 0.0389 0.0544
Echinococcus granulosus atrial natriuretic peptide receptor 0.0068 0.0017 0.0002
Schistosoma mansoni serine/threonine protein kinase 0.0223 0.0598 0.0692
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0127 0.0239 0.026
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0097 0.0129 0.0171
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0115 0.0194 0.0194
Loa Loa (eye worm) hypothetical protein 0.0122 0.022 0.0254
Brugia malayi Variant SH3 domain containing protein 0.0098 0.013 0.0136
Leishmania major casein kinase, putative 0.0198 0.0504 0.0709
Brugia malayi Hr1 repeat family protein 0.0352 0.1077 0.1235
Schistosoma mansoni protein kinase 0.0167 0.0387 0.0446
Echinococcus multilocularis rac serine:threonine kinase 0.0179 0.0433 0.0485
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.0191 0.169
Entamoeba histolytica protein kinase, putative 0.0136 0.0273 0.2279
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0127 0.0239 0.026
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.0152 0.1323
Echinococcus granulosus tyrosine protein kinase Fyn 0.0232 0.0632 0.0716
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0085 0.0083 0.0079
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0232 0.0632 0.0716
Schistosoma mansoni serine/threonine protein kinase 0.0268 0.0763 0.0882
Loa Loa (eye worm) glycogen phosphorylase 0.013 0.0251 0.029
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.0172 0.1515
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0153 0.1336
Entamoeba histolytica protein kinase, putative 0.0346 0.1055 0.9028
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.0152 0.1323
Schistosoma mansoni tyrosine kinase 0.0607 0.203 0.2351
Brugia malayi serine/threonine kinase 12 0.0159 0.0359 0.0401
Entamoeba histolytica protein kinase, putative 0.0085 0.0083 0.0641
Trypanosoma cruzi ABC1 protein, putative 0.0098 0.0132 0.0176
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0171 0.1502
Schistosoma mansoni tyrosine kinase 0.0116 0.0196 0.0225
Echinococcus multilocularis CDC7 cell division cycle 7 0.0104 0.0153 0.016
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0232 0.0632 0.0716
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0098 0.0131 0.0122
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0409 0.1292 0.1483
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0171 0.1502
Brugia malayi Protein kinase c protein 2 0.013 0.0249 0.0273
Schistosoma mansoni serine/threonine-protein kinase 0.0179 0.0433 0.05
Brugia malayi Serine/threonine-protein kinase SULU 0.0235 0.0642 0.0729
Trichomonas vaginalis CMGC family protein kinase 0.0167 0.0389 0.3521
Brugia malayi casein kinase I 0.0198 0.0504 0.057
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0104 0.0152 0.0152
Schistosoma mansoni serine/threonine protein kinase 0.0283 0.0819 0.0948
Schistosoma mansoni serine/threonine protein kinase 0.0159 0.0359 0.0414
Echinococcus multilocularis tyrosine protein kinase shark 0.0316 0.0944 0.1078
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.0152 0.1323
Trypanosoma cruzi rac serine-threonine kinase, putative 0.017 0.04 0.056
Plasmodium vivax serine/threonine protein kinase, putative 0.0097 0.0129 0.0129
Brugia malayi Protein kinase domain containing protein 0.0223 0.0598 0.0679
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0122 0.1052
Loa Loa (eye worm) hypothetical protein 0.0141 0.0292 0.0337
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0335 0.3019
Brugia malayi Fes/CIP4 homology domain containing protein 0.0116 0.0196 0.0212
Brugia malayi Protein kinase domain containing protein 0.0555 0.1835 0.2114
Echinococcus multilocularis twitchin 0.0069 0.0024 0.001
Entamoeba histolytica protein kinase, putative 0.0097 0.0129 0.1032
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0098 0.013 0.015
Entamoeba histolytica protein kinase domain containing protein 0.0143 0.0297 0.2484
Trichomonas vaginalis serine/threonine-protein kinase ypk, putative 0.0109 0.0171 0.1502
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0248 0.0689 0.0783
Schistosoma mansoni vam6/vps39 related 0.0111 0.0177 0.0203
Loa Loa (eye worm) protein kinase domain-containing protein 0.0226 0.0609 0.0705
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0223 0.0598 0.0677
Loa Loa (eye worm) AUR protein kinase 0.0159 0.0359 0.0415
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0097 0.0129 0.0148
Echinococcus granulosus serine/threonine protein kinase 0.0179 0.0433 0.0485
Echinococcus granulosus Glutaredoxin protein 5 0.0122 0.0221 0.0239
Brugia malayi Immunoglobulin I-set domain containing protein 0.0629 0.2112 0.2437
Trichomonas vaginalis AGC family protein kinase 0.0355 0.1088 1
Loa Loa (eye worm) TK/FAK protein kinase 0.0555 0.1835 0.2126
Trypanosoma cruzi Protein kinase B 0.0179 0.0433 0.0607
Schistosoma mansoni glycogen phosphorylase 0.013 0.0251 0.0289
Brugia malayi C1-like domain containing protein 0.0231 0.0625 0.071
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0127 0.0239 0.023
Loa Loa (eye worm) CAMK protein kinase 0.0085 0.0081 0.0093
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0128 0.0243 0.0281
Schistosoma mansoni serine/threonine protein kinase 0.0127 0.0239 0.0275
Schistosoma mansoni serine/threonine protein kinase 0.0104 0.0152 0.0174
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0115 0.0194 0.0208
Echinococcus granulosus protein kinase 0.0167 0.0387 0.0432
Echinococcus granulosus rho-associated protein kinase 1 0.0337 0.1022 0.1169
Brugia malayi hypothetical protein 0.0068 0.0017 0.0004
Brugia malayi cell division control protein 2 homolog 0.0133 0.026 0.0286
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0199 0.0507 0.0572
Trichomonas vaginalis AGC family protein kinase 0.0118 0.0204 0.1808
Trichomonas vaginalis AGC family protein kinase 0.0355 0.1088 1
Trypanosoma cruzi ULK family serine/threonine-protein kinase, putative 0.0109 0.0172 0.0234
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0129 0.0147
Loa Loa (eye worm) TK/FER protein kinase 0.0105 0.0156 0.0179
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0391 0.1224 0.1404
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0096 0.0123 0.0114
Echinococcus multilocularis tyrosine kinase 0.0105 0.0156 0.0163
Echinococcus granulosus nervana 2 0.0122 0.0221 0.0239
Echinococcus granulosus nmda type glutamate receptor 0.0068 0.0017 0.0002
Entamoeba histolytica casein kinase 1, putative 0.0198 0.0504 0.4276
Loa Loa (eye worm) NAK/GAK protein kinase 0.0189 0.047 0.0544
Brugia malayi Receptor family ligand binding region containing protein 0.0184 0.0452 0.0509
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0133 0.026 0.0301
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0184 0.0452 0.0523
Echinococcus multilocularis growth factor receptor bound protein 2 0.0097 0.0128 0.0131
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.0152 0.1323
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0244 0.0676 0.0767
Loa Loa (eye worm) hypothetical protein 0.0279 0.0805 0.0933
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.0152 0.1323
Giardia lamblia Kinase, CAMK CAMKL 0.0104 0.0152 0.1762
Trypanosoma brucei rac serine-threonine kinase, putative 0.0355 0.1088 0.1545
Loa Loa (eye worm) hypothetical protein 0.0179 0.0431 0.0499
Loa Loa (eye worm) hypothetical protein 0.0137 0.0277 0.032
Trypanosoma brucei casein kinase I, isoform 2 0.0198 0.0504 0.0709
Trichomonas vaginalis CAMK family protein kinase 0.014 0.0288 0.2588
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0069 0.0023 0.0011
Echinococcus granulosus expressed protein 0.0097 0.0129 0.0132
Trichomonas vaginalis CAMK family protein kinase 0.0283 0.0819 0.7511
Schistosoma mansoni serine/threonine protein kinase 0.012 0.0212 0.0243
Onchocerca volvulus 0.0312 0.0929 0.5108
Schistosoma mansoni hypothetical protein 0.0117 0.02 0.0229
Brugia malayi Protein kinase domain containing protein 0.0312 0.0929 0.1062
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0359 0.3242
Onchocerca volvulus 0.0105 0.0156 0.0852
Echinococcus multilocularis death associated protein kinase 1 0.0854 0.2953 0.3412
Brugia malayi chaperone-activity of bc1 complex-like, mitochondrial, putative 0.0098 0.0132 0.0137
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.0152 0.1323
Brugia malayi phosphoinositide-dependent protein kinase I 0.0096 0.0122 0.0126
Schistosoma mansoni serine/threonine protein kinase 0.0223 0.0598 0.0692
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0232 0.0632 0.0716
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0148 0.0319 0.0352
Giardia lamblia Glycogen phosphorylase 0.013 0.0251 0.299
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0114 0.0191 0.0221
Echinococcus multilocularis serine:threonine protein kinase 36 0.0109 0.0172 0.0183
Brugia malayi Protein kinase domain containing protein 0.0105 0.0156 0.0165
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0229 0.0619 0.0701
Echinococcus multilocularis ephrin type A receptor 4 A 0.0111 0.0181 0.0192
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0097 0.0129 0.0171
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0115 0.0194 0.0208
Trichomonas vaginalis CAMK family protein kinase 0.0283 0.0819 0.7511
Echinococcus multilocularis cyclin dependent kinase 5 0.0133 0.026 0.0285
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0069 0.0023 0.0134
Schistosoma mansoni ABC transporter 0.0098 0.0132 0.015
Plasmodium vivax casein kinase 1, putative 0.0198 0.0504 0.0504
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0153 0.0335 0.0387
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0079 0.006 0.0052
Echinococcus multilocularis dual specificity 0.0136 0.0273 0.0299
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0283 0.0819 0.0934
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0136 0.0273 0.0315
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0122 0.0221 0.0239
Trichomonas vaginalis glycogen phosphorylase, putative 0.013 0.0251 0.2246
Loa Loa (eye worm) Skb1 methyltransferase 0.0153 0.0336 0.0388
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0378 0.1175 0.1347
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.0131 0.0149
Entamoeba histolytica PH domain containing protein kinase, putative 0.0136 0.0272 0.227
Plasmodium vivax glycogen synthase kinase 3, putative 0.0143 0.0297 0.0297
Echinococcus multilocularis serine:threonine protein kinase 3 0.0269 0.077 0.0876
Brugia malayi hypothetical protein 0.0105 0.0156 0.0165
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0133 0.026 0.0285
Onchocerca volvulus 0.0183 0.0446 0.2452
Giardia lamblia Kinase, PLK 0.0283 0.0819 1
Schistosoma mansoni tyrosine kinase 0.0353 0.1082 0.1252
Echinococcus granulosus cGMP dependent protein kinase 1 0.0148 0.0319 0.0352
Schistosoma mansoni serine/threonine protein kinase 0.0104 0.0152 0.0174
Entamoeba histolytica protein kinase, putative 0.0088 0.0092 0.0718
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0104 0.0152 0.0204
Onchocerca volvulus Serine\/threonine kinase homolog 0.0178 0.0427 0.2348
Echinococcus multilocularis casein kinase I delta 0.0198 0.0504 0.0568
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.1937 0.6992 0.8107
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0171 0.1502
Loa Loa (eye worm) hypothetical protein 0.0101 0.014 0.0161
Brugia malayi Protein kinase domain containing protein 0.0136 0.0273 0.0301
Trypanosoma cruzi polo-like protein kinase, putative 0.0283 0.0819 0.116
Trichomonas vaginalis AGC family protein kinase 0.0284 0.0826 0.7573
Schistosoma mansoni growth factor receptor-bound protein 0.0097 0.0128 0.0146
Trichomonas vaginalis glycogen phosphorylase, putative 0.013 0.0251 0.2246
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0189 0.0471 0.0545
Brugia malayi Tyrosine-protein kinase abl-1 0.0127 0.0238 0.026
Echinococcus multilocularis mitogen activated protein kinase 3 0.0098 0.0131 0.0134
Plasmodium falciparum calcium-dependent protein kinase 1 0.0115 0.0194 0.0185
Echinococcus multilocularis Glycosyl transferase, family 35 0.013 0.0251 0.0274
Brugia malayi serine/threonine-protein kinase plk-2 0.0283 0.0819 0.0935
Schistosoma mansoni serine/threonine protein kinase 0.0167 0.0389 0.0448
Echinococcus multilocularis mitogen activated protein kinase 14 0.1937 0.6992 0.8104
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0096 0.0122 0.0141
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0127 0.0239 0.0329
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0133 0.026 0.036
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0244 0.0676 0.0767
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0096 0.0122 0.0125
Echinococcus multilocularis mitogen activated protein kinase 0.0098 0.0131 0.0134
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0153 0.0335 0.0466
Loa Loa (eye worm) AUR protein kinase 0.0159 0.0359 0.0415
Plasmodium falciparum serine/threonine protein kinase KIN 0.0104 0.0152 0.0143
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.0172 0.1515
Echinococcus granulosus tyrosine kinase 0.0116 0.0196 0.021
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0178 0.0427 0.0479
Echinococcus multilocularis N chimaerin 0.0098 0.013 0.0134
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0118 0.0204 0.1808
Entamoeba histolytica serine/threonine protein kinase, putative 0.0104 0.0152 0.1232
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0148 0.0319 0.0352
Entamoeba histolytica protein kinase domain containing protein 0.0114 0.0191 0.1574
Leishmania major protein kinase A catalytic subunit isoform 2 0.0127 0.0239 0.0329
Leishmania major protein kinase A catalytic subunit 0.0127 0.0239 0.0329
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0127 0.0239 0.026
Trichomonas vaginalis STE family protein kinase 0.01 0.0139 0.1207
Schistosoma mansoni tyrosine kinase 0.0353 0.1082 0.1252
Onchocerca volvulus 0.015 0.0326 0.1788
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0167 0.0389 0.0544
Echinococcus multilocularis serine:threonine protein kinase N2 0.0352 0.1077 0.1233
Echinococcus granulosus cyclin dependent kinase 1 0.0133 0.026 0.0285
Trichomonas vaginalis cAMP-dependent protein kinase catalytic subunit, putative 0.0109 0.0171 0.1502
Echinococcus multilocularis nervana 2 0.0122 0.0221 0.0239
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0098 0.0131 0.0174
Loa Loa (eye worm) hypothetical protein 0.0361 0.1111 0.1287
Echinococcus multilocularis protein tyrosine kinase 0.0549 0.1812 0.2087
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0127 0.0239 0.0329
Giardia lamblia Kinase, CMGC SRPK 0.0097 0.0129 0.1475
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0148 0.0319 0.031
Trypanosoma cruzi cdc2-related kinase 3 0.0133 0.026 0.036
Loa Loa (eye worm) hypothetical protein 0.0299 0.0882 0.1022
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0229 0.0619 0.0701
Brugia malayi Kinase associated domain 1 family protein 0.0101 0.0141 0.0147
Echinococcus multilocularis serine:threonine protein kinase 0.0128 0.0243 0.0264
Schistosoma mansoni serine/threonine protein kinase 0.0198 0.0504 0.0582
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0177 0.0426 0.0493
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0401 0.1261 0.1447
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0283 0.0819 0.0949
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0283 0.0819 0.0934
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0171 0.1502
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0127 0.0239 0.0329
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0127 0.0239 0.0329
Brugia malayi Immunoglobulin I-set domain containing protein 0.0098 0.013 0.0135
Brugia malayi Protein kinase domain containing protein 0.0133 0.026 0.0286
Loa Loa (eye worm) hypothetical protein 0.0065 0.0009 0.0009
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0098 0.013 0.0134
Schistosoma mansoni tyrosine kinase 0.0446 0.143 0.1656
Schistosoma mansoni tensin 0.0071 0.0029 0.0031
Schistosoma mansoni serine/threonine protein kinase 0.0199 0.0507 0.0586
Schistosoma mansoni serine/threonine protein kinase 0.0065 0.0009 0.0008
Schistosoma mansoni protein kinase 0.0159 0.0359 0.0414
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0105 0.0156 0.1267
Giardia lamblia Kinase, AGC PKA 0.0127 0.0239 0.2838
Schistosoma mansoni protein kinase 0.0079 0.0059 0.0066
Brugia malayi Protein kinase domain containing protein 0.0282 0.0817 0.0933
Schistosoma mansoni serine/threonine protein kinase 0.0391 0.1224 0.1417
Trichomonas vaginalis STE family protein kinase 0.0079 0.0059 0.0466
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0206 0.0533 0.0617
Leishmania major casein kinase II, putative 0.0114 0.0191 0.0261
Brugia malayi p70 ribosomal S6 kinase beta 0.0346 0.1055 0.1209
Schistosoma mansoni shk1 kinase-binding protein 0.0153 0.0336 0.0387
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0097 0.0128 0.0146
Echinococcus multilocularis GPCR, family 3, C terminal 0.0117 0.02 0.0215
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0335 0.3019
Brugia malayi Protein kinase domain containing protein 0.023 0.0623 0.0707
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0117 0.02 0.0216
Schistosoma mansoni serine/threonine protein kinase 0.0133 0.026 0.0299
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0153 0.1336
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0651 0.2194 0.2532
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0232 0.0632 0.0716
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0097 0.0128 0.0147
Schistosoma mansoni tyrosine kinase 0.0401 0.1261 0.146
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0171 0.1502
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0399 0.1253 0.1452
Schistosoma mansoni growth factor receptor-bound protein 0.0099 0.0135 0.0154
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0143 0.0297 0.0342
Giardia lamblia Kinase, CMGC DYRK 0.0153 0.0335 0.402
Plasmodium falciparum glycogen synthase kinase 3 0.0143 0.0297 0.0288
Loa Loa (eye worm) AUR protein kinase 0.0159 0.0359 0.0415
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0068 0.0017 0.0004
Loa Loa (eye worm) hypothetical protein 0.0068 0.0017 0.0018
Brugia malayi Cam kinase protein 1 0.0115 0.0194 0.0209
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0171 0.1502
Trichomonas vaginalis CAMK family protein kinase 0.014 0.0288 0.2588
Echinococcus multilocularis serine:threonine protein kinase N2 0.0223 0.0598 0.0677
Schistosoma mansoni nck2/grb4 0.0097 0.0128 0.0146
Trypanosoma brucei cdc2-related kinase 1 0.0133 0.026 0.036
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0098 0.013 0.0134
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0104 0.0152 0.0204
Trichomonas vaginalis AGC family protein kinase 0.0293 0.0859 0.7879
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1009 0.353 0.4082
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0364 0.1123 0.1287
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0164 0.0378 0.0438
Brugia malayi Variant SH3 domain containing protein 0.0097 0.0128 0.0132
Brugia malayi Tyrosine-protein kinase abl-1 0.0224 0.06 0.0681
Echinococcus granulosus casein kinase I delta 0.0198 0.0504 0.0568
Echinococcus granulosus dual specificity 0.0153 0.0335 0.0371
Echinococcus multilocularis tyrosine protein kinase Blk 0.0192 0.048 0.054
Echinococcus granulosus tyrosine protein kinase HCK 0.0135 0.0269 0.0295
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0167 0.0389 0.0544
Echinococcus granulosus receptor type guanylyl cyclase 0.0116 0.0196 0.021
Loa Loa (eye worm) hypothetical protein 0.0206 0.0533 0.0617
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0105 0.0155 0.1259
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0247 0.2202
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0167 0.0389 0.0544
Echinococcus multilocularis aurora kinase A 0.0159 0.0359 0.0399
Trichomonas vaginalis STE family protein kinase 0.01 0.0139 0.1207
Echinococcus multilocularis raf serine:threonine protein kinase 0.0089 0.0099 0.0097
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0171 0.1502
Echinococcus granulosus protein kinase C gamma type 0.0264 0.0749 0.0853
Trypanosoma cruzi arginine N-methyltransferase, type II, putative 0.0098 0.013 0.0174
Schistosoma mansoni serine/threonine protein kinase 0.0069 0.0024 0.0025
Loa Loa (eye worm) AGC/AKT protein kinase 0.0355 0.1088 0.126
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0099 0.0134 0.0179
Echinococcus granulosus glutamate receptor 2 0.0068 0.0017 0.0002
Schistosoma mansoni glutamate receptor NMDA 0.0068 0.0017 0.0017
Schistosoma mansoni protein kinase 0.0277 0.0799 0.0925
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0192 0.048 0.054
Echinococcus granulosus tyrosine protein kinase shark 0.0316 0.0944 0.1078
Schistosoma mansoni serine/threonine protein kinase 0.0069 0.0023 0.0025
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0159 0.0356 0.0396
Brugia malayi Casein kinase II, alpha chain 0.0114 0.0191 0.0206
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0068 0.0017 0.0002
Loa Loa (eye worm) hypothetical protein 0.0264 0.0749 0.0867
Echinococcus multilocularis tyrosine protein kinase HCK 0.0135 0.0269 0.0295
Echinococcus granulosus ephrin type A receptor 4 A 0.0111 0.0181 0.0192
Loa Loa (eye worm) hypothetical protein 0.0088 0.0094 0.0108
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0153 0.0335 0.0466
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0199 0.0507 0.0573
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0096 0.0123 0.0163
Brugia malayi Protein kinase domain containing protein 0.0167 0.0389 0.0436
Trichomonas vaginalis AGC family protein kinase 0.0127 0.0239 0.2132
Schistosoma mansoni protein kinase 0.0116 0.0196 0.0225
Echinococcus multilocularis casein kinase I alpha 0.0198 0.0504 0.0568
Loa Loa (eye worm) hypothetical protein 0.0118 0.0204 0.0235
Loa Loa (eye worm) thyroid receptor interactor 0.0116 0.0196 0.0227
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0885 0.3066 0.3543
Echinococcus granulosus tyrosine protein kinase Src64B 0.0232 0.0632 0.0716
Trichomonas vaginalis shk1 kinase-binding protein, putative 0.0098 0.013 0.1126
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0335 0.3019
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0133 0.026 0.0252
Trichomonas vaginalis CMGC family protein kinase 0.0133 0.026 0.2329
Toxoplasma gondii AGC kinase 0.0346 0.1055 0.1047
Schistosoma mansoni serine/threonine protein kinase 0.0149 0.0319 0.0368
Schistosoma mansoni serine/threonine protein kinase 0.0229 0.0619 0.0715
Entamoeba histolytica cell division protein kinase 2, putative 0.0133 0.026 0.2169
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0229 0.0621 0.0703
Trypanosoma brucei SNF1-related protein kinases, putative 0.0104 0.0152 0.0204
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0127 0.0239 0.0239
Echinococcus granulosus cGMP dependent protein kinase 1 0.0148 0.0319 0.0352
Echinococcus granulosus protein arginine N methyltransferase 5 0.0153 0.0336 0.0372
Echinococcus multilocularis dual specificity 0.0153 0.0335 0.0371
Trichomonas vaginalis AGC family protein kinase 0.0118 0.0204 0.1808
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0115 0.0194 0.0208
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0069 0.0023 0.0021
Echinococcus granulosus hypothetical protein 0.0119 0.021 0.0226
Trichomonas vaginalis shk1 kinase-binding protein, putative 0.0098 0.013 0.1126
Brugia malayi SH2 domain containing protein 0.0405 0.1275 0.1465
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0305 0.0904 0.1032
Echinococcus granulosus ABC domain containing protein kinase 0.0098 0.0132 0.0135
Entamoeba histolytica hypothetical protein 0.0376 0.1167 1
Loa Loa (eye worm) SRC-1 0.0232 0.0632 0.0732
Echinococcus granulosus cyclin dependent kinase 5 0.0133 0.026 0.0285
Schistosoma mansoni serine/threonine protein kinase 0.0148 0.0319 0.0367
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.01 0.0139 0.0144
Trichomonas vaginalis AGC family protein kinase 0.0355 0.1088 1
Schistosoma mansoni ste20-related kinase 0.0218 0.0579 0.0669
Trichomonas vaginalis CMGC family protein kinase 0.0133 0.026 0.2329
Echinococcus multilocularis myosin iiia 0.0099 0.0134 0.0138
Schistosoma mansoni serine/threonine protein kinase 0.0127 0.0239 0.0275
Trypanosoma brucei arginine N-methyltransferase, type II 0.0098 0.013 0.0174
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0098 0.0131 0.0174
Echinococcus multilocularis dual specificity testis specific protein kinase 0.025 0.0697 0.0792
Giardia lamblia Kinase, STE STE20 0.0099 0.0134 0.1546
Trichomonas vaginalis AGC family protein kinase 0.0118 0.0204 0.1808
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0283 0.0819 0.116
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0223 0.0598 0.0677
Brugia malayi Protein kinase domain containing protein 0.0355 0.1088 0.1247
Trypanosoma cruzi Wee1-like protein kinase, putative 0.0104 0.0153 0.0206
Brugia malayi SRC-1 0.0232 0.0632 0.0718
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0167 0.0389 0.038
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0127 0.0239 0.0329
Trichomonas vaginalis AGC family protein kinase 0.0118 0.0204 0.1808
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0097 0.0129 0.012
Loa Loa (eye worm) TK/ROR protein kinase 0.007 0.0024 0.0027
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0198 0.0504 0.0584
Echinococcus multilocularis PAK box P21 Rho binding 0.0079 0.0059 0.0051
Trichomonas vaginalis CAMK family protein kinase 0.0283 0.0819 0.7511
Schistosoma mansoni protein kinase 0.0444 0.1423 0.1648
Brugia malayi Protein kinase domain containing protein 0.0105 0.0156 0.0165
Echinococcus multilocularis mitogen activated protein kinase 11 0.1937 0.6992 0.8104
Schistosoma mansoni ephrin receptor 0.0111 0.0181 0.0207
Trypanosoma cruzi casein kinase, putative 0.0198 0.0504 0.0709
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0232 0.0632 0.0716
Onchocerca volvulus 0.0116 0.0196 0.1076
Schistosoma mansoni protein kinase 0.0444 0.1423 0.1648
Plasmodium falciparum casein kinase 1 0.0198 0.0504 0.0496
Loa Loa (eye worm) hypothetical protein 0.0128 0.0243 0.0281
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0198 0.0504 0.0584
Echinococcus multilocularis dual specificity 0.0153 0.0335 0.0371
Schistosoma mansoni serine/threonine protein kinase 0.0305 0.0904 0.1046
Schistosoma mansoni serine/threonine protein kinase 0.0149 0.0319 0.0368
Entamoeba histolytica protein kinase, putative 0.01 0.0139 0.1124
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0329 0.0994 0.1138
Echinococcus multilocularis dual specificity 0.0153 0.0335 0.0371
Echinococcus granulosus mitogen activated protein kinase 0.0098 0.0131 0.0134
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0131 0.1129
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0131 0.1129
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0143 0.0297 0.0343
Brugia malayi Doublecortin family protein 0.0164 0.0378 0.0423
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0335 0.3019
Loa Loa (eye worm) TK protein kinase 0.0348 0.1064 0.1233
Plasmodium vivax unspecified product 0.0114 0.0191 0.0191
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0172 0.1515
Giardia lamblia Kinase, NEK 0.015 0.0324 0.3891
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0127 0.0239 0.0261
Brugia malayi Receptor family ligand binding region containing protein 0.0116 0.0196 0.0212
Echinococcus granulosus titin 0.0085 0.0081 0.0077
Onchocerca volvulus 0.0105 0.0156 0.0852
Trichomonas vaginalis AGC family protein kinase 0.0118 0.0204 0.1808
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0232 0.0632 0.0716
Schistosoma mansoni vav2 0.0107 0.0163 0.0187
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0083 0.0073 0.0082
Plasmodium vivax 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative 0.2743 1 1
Giardia lamblia Aurora kinase 0.0159 0.0359 0.4316
Trypanosoma cruzi casein kinase, delta isoform, putative 0.015 0.0326 0.0453
Echinococcus granulosus dual specificity protein kinase clk2 0.0167 0.0389 0.0434
Onchocerca volvulus 0.0198 0.0504 0.2772
Schistosoma mansoni serine/threonine protein kinase 0.0216 0.057 0.0658
Brugia malayi carbohydrate phosphorylase 0.013 0.0251 0.0276
Echinococcus multilocularis nervana 2 0.0122 0.0221 0.0239
Echinococcus granulosus protein kinase c epsilon type 0.0266 0.0757 0.0862
Trypanosoma cruzi casein kinase II, putative 0.0114 0.0191 0.0261
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0098 0.0131 0.0174
Brugia malayi Stress-activated protein kinase jnk-1 0.2374 0.8625 1
Schistosoma mansoni serine/threonine protein kinase 0.0104 0.0153 0.0175
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.0152 0.1323
Giardia lamblia Kinase, CMGC MAPK 0.0098 0.0131 0.1504
Trichomonas vaginalis AGC family protein kinase 0.0118 0.0204 0.1808
Brugia malayi Immunoglobulin I-set domain containing protein 0.0266 0.0756 0.0862
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0111 0.0177 0.0241
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0171 0.1502
Plasmodium falciparum calcium-dependent protein kinase 2 0.0115 0.0194 0.0185
Echinococcus granulosus tyrosine protein kinase Blk 0.0192 0.048 0.054
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0118 0.0204 0.1808
Echinococcus multilocularis tyrosine protein kinase Srms 0.0192 0.048 0.054
Loa Loa (eye worm) CMGC/MAPK/NMO protein kinase 0.0347 0.1061 0.1229
Trichomonas vaginalis STE family protein kinase 0.0099 0.0134 0.1161
Echinococcus multilocularis mitogen activated protein kinase 11 0.1937 0.6992 0.8104
Loa Loa (eye worm) hypothetical protein 0.0101 0.0141 0.0162
Trichomonas vaginalis CAMK family protein kinase 0.023 0.0623 0.5687
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0115 0.0194 0.0224
Brugia malayi Protein kinase domain containing protein 0.0105 0.0156 0.0165
Entamoeba histolytica protein kinase, putative 0.0079 0.0059 0.0434
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0235 0.0642 0.0728
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0143 0.0297 0.0412
Echinococcus granulosus serine:threonine protein kinase 36 0.0109 0.0172 0.0183
Loa Loa (eye worm) TK/EGFR protein kinase 0.0607 0.203 0.2352
Trypanosoma brucei wee1-like protein kinase 0.0104 0.0153 0.0206
Trypanosoma cruzi polo-like protein kinase, putative 0.0283 0.0819 0.116
Schistosoma mansoni protein kinase 0.0444 0.1423 0.1648
Entamoeba histolytica protein kinase domain containing protein 0.0143 0.0297 0.2484
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0099 0.0134 0.0179
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0067 0.0014 0.0015
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0192 0.048 0.054
Brugia malayi Protein kinase domain containing protein 0.0364 0.1123 0.1288
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0629 0.2112 0.2448
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0229 0.0619 0.0701
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.0194 0.0222
Schistosoma mansoni adapter molecule crk 0.0097 0.0128 0.0146
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0248 0.0689 0.0783
Echinococcus multilocularis casein kinase I gamma 0.0226 0.0609 0.0689
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0127 0.0239 0.0329
Giardia lamblia Kinase, CMGC GSK 0.0143 0.0297 0.355
Trichomonas vaginalis AGC family protein kinase 0.0355 0.1088 1
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0171 0.1502
Echinococcus granulosus roundabout 2 0.0138 0.0278 0.0305
Echinococcus multilocularis ABC domain containing protein kinase 0.0098 0.0132 0.0135
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0096 0.0122 0.0125
Schistosoma mansoni serine/threonine protein kinase 0.2374 0.8625 1
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0171 0.1502
Loa Loa (eye worm) TK/FER protein kinase 0.0405 0.1275 0.1478
Echinococcus granulosus epidermal growth factor receptor 0.0401 0.1261 0.1447
Entamoeba histolytica protein kinase, putative 0.0097 0.0129 0.1032
Brugia malayi serine/threonine protein kinase 6 0.0159 0.0359 0.0401
Toxoplasma gondii AGC kinase 0.0127 0.0239 0.023
Trichomonas vaginalis STE family protein kinase 0.01 0.0139 0.1207
Loa Loa (eye worm) AGC/NDR protein kinase 0.0223 0.0598 0.0693
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0346 0.1055 0.1222
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0115 0.0194 0.0208
Brugia malayi Protein kinase domain containing protein 0.0076 0.005 0.0042
Trichomonas vaginalis STE family protein kinase 0.015 0.0324 0.2922
Echinococcus multilocularis tyrosine protein kinase 0.0285 0.0829 0.0945
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0083 0.0073 0.0082
Entamoeba histolytica protein kinase , putative 0.0159 0.0359 0.3019
Loa Loa (eye worm) TK/ABL protein kinase 0.031 0.0921 0.1067
Echinococcus granulosus activin receptor type 0.0096 0.0123 0.0125
Echinococcus granulosus casein kinase I gamma 0.0226 0.0609 0.0689
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0198 0.0504 0.0584
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0198 0.0504 0.0709
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0378 0.1175 0.1362
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0143 0.0297 0.0288
Echinococcus multilocularis activin receptor type 0.0096 0.0123 0.0125
Schistosoma mansoni nephrin 0.0119 0.021 0.0242
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.1937 0.6992 1
Echinococcus granulosus epidermal growth factor receptor 0.0607 0.203 0.234
Schistosoma mansoni serine/threonine protein kinase 0.0364 0.1123 0.13
Echinococcus granulosus mitogen activated protein kinase 14 0.1937 0.6992 0.8104
Schistosoma mansoni vesicular amine transporter 0.0083 0.0073 0.0082
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0232 0.0632 0.0716
Echinococcus multilocularis tyrosine protein kinase Abl 0.0224 0.06 0.0679
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0127 0.0239 0.023
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.017 0.04 0.04
Loa Loa (eye worm) TK protein kinase 0.0266 0.0756 0.0876
Echinococcus granulosus casein kinase i 0.0198 0.0504 0.0568
Brugia malayi Protein kinase domain containing protein 0.0284 0.0826 0.0943
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.0191 0.169
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0129 0.0247 0.0269
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0129 0.0247 0.0269
Entamoeba histolytica protein kinase 2, putative 0.017 0.04 0.3374
Echinococcus multilocularis insulin receptor 0.0446 0.143 0.1643
Echinococcus multilocularis casein kinase I alpha 0.0198 0.0504 0.0568
Echinococcus granulosus metabotropic glutamate receptor 2 0.0602 0.2011 0.2318
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0231 0.0625 0.0724
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0104 0.0153 0.0206
Echinococcus granulosus casein kinase ii subunit alpha 0.0114 0.0191 0.0204
Giardia lamblia Kinase, NEK 0.015 0.0324 0.3891
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0115 0.0194 0.0224
Brugia malayi Protein kinase domain containing protein 0.0189 0.047 0.053
Onchocerca volvulus 0.0104 0.0153 0.0838
Schistosoma mansoni serine/threonine protein kinase 0.0127 0.0239 0.0275
Echinococcus multilocularis casein kinase i 0.0198 0.0504 0.0568
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0068 0.0017 0.0002
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0153 0.0335 0.0466
Brugia malayi protein kinase C II. 0.0266 0.0757 0.0864
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0153 0.0335 0.0373
Brugia malayi Protein kinase domain containing protein 0.0206 0.0533 0.0603
Brugia malayi Furin-like cysteine rich region family protein 0.0607 0.203 0.2341
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0817 0.2814 0.3261
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0364 0.1123 0.1301
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0115 0.0194 0.0185
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0131 0.1129
Trichomonas vaginalis AGC family protein kinase 0.0355 0.1088 1
Trypanosoma cruzi casein kinase, putative 0.0198 0.0504 0.0709
Echinococcus granulosus casein kinase I delta 0.0198 0.0504 0.0568
Echinococcus multilocularis Glutaredoxin protein 5 0.0122 0.0221 0.0239
Loa Loa (eye worm) hypothetical protein 0.0083 0.0073 0.0083
Schistosoma mansoni serine/threonine protein kinase 0.0229 0.0619 0.0715
Loa Loa (eye worm) TK protein kinase 0.0192 0.048 0.0556
Loa Loa (eye worm) TK/FER protein kinase 0.0105 0.0156 0.0179
Loa Loa (eye worm) hypothetical protein 0.0097 0.0128 0.0147
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.0191 0.169
Loa Loa (eye worm) TK/FER protein kinase 0.0105 0.0156 0.0179
Onchocerca volvulus 0.0141 0.0292 0.1602
Onchocerca volvulus Serine\/threonine kinase homolog 0.0283 0.0819 0.4506
Loa Loa (eye worm) hypothetical protein 0.0137 0.0277 0.032
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0153 0.1336
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.0191 0.169
Echinococcus multilocularis protein kinase c epsilon type 0.0266 0.0757 0.0862
Plasmodium falciparum NIMA related kinase 1 0.015 0.0324 0.0316
Brugia malayi Protein kinase domain containing protein 0.0105 0.0156 0.0165
Trypanosoma brucei protein kinase, putative 0.0143 0.0297 0.0412
Brugia malayi Temporarily assigned gene name protein 59 0.0128 0.0241 0.0264
Loa Loa (eye worm) hypothetical protein 0.0068 0.0017 0.0018
Toxoplasma gondii casein kinase I 0.0198 0.0504 0.0496
Schistosoma mansoni serine/threonine protein kinase 0.0189 0.047 0.0543
Schistosoma mansoni glycogen phosphorylase 0.013 0.0251 0.0289
Echinococcus multilocularis rho associated protein kinase 0.0337 0.1022 0.1169
Trichomonas vaginalis AGC family protein kinase 0.0118 0.0204 0.1808
Trichomonas vaginalis AGC family protein kinase 0.0284 0.0826 0.7573
Schistosoma mansoni metabotropic glutamate receptor 0.035 0.1072 0.124
Loa Loa (eye worm) hypothetical protein 0.0111 0.0177 0.0204
Echinococcus granulosus aurora kinase A 0.0159 0.0359 0.0399
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.015 0.0324 0.0316
Echinococcus multilocularis protein kinase shaggy 0.0143 0.0297 0.0327
Mycobacterium ulcerans hypothetical protein 0.0101 0.014 0.0008
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0068 0.0017 0.0002
Trichomonas vaginalis CAMK family protein kinase 0.0128 0.0243 0.2169
Leishmania major extracellular receptor, putative 0.0068 0.0017 0.0011
Echinococcus multilocularis cyclin dependent kinase 1 0.0133 0.026 0.0285
Schistosoma mansoni serine/threonine protein kinase 0.0337 0.1022 0.1182
Plasmodium falciparum protein kinase, putative 0.0096 0.0123 0.0114
Loa Loa (eye worm) hypothetical protein 0.0083 0.0074 0.0084
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.0152 0.1323
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.0152 0.1323
Echinococcus granulosus protein kinase shaggy 0.0143 0.0297 0.0327
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0085 0.0081 0.0093
Echinococcus granulosus casein kinase I alpha 0.0198 0.0504 0.0568
Echinococcus granulosus tyrosine kinase 0.0192 0.048 0.054
Echinococcus granulosus discoidin domain receptor 0.0264 0.0749 0.0852
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.0152 0.1323
Loa Loa (eye worm) hypothetical protein 0.0141 0.0292 0.0337
Echinococcus granulosus c-Jun N-terminal kinases 0.2374 0.8625 1
Entamoeba histolytica PH domain containing protein kinase, putative 0.0136 0.0272 0.227
Schistosoma mansoni protein kinase 0.0198 0.0504 0.0582
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.0191 0.169
Echinococcus granulosus cGMP dependent protein kinase 0.0148 0.0319 0.0352
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0171 0.1502
Giardia lamblia Kinase, CMGC CLK 0.0167 0.0389 0.4688
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0111 0.0177 0.0241
Loa Loa (eye worm) hypothetical protein 0.0068 0.0017 0.0018
Echinococcus multilocularis serine:threonine protein kinase NLK 0.0347 0.1061 0.1214
Schistosoma mansoni hypothetical protein 0.0101 0.0141 0.0161
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0133 0.026 0.0301
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0104 0.0152 0.0204
Onchocerca volvulus 0.0105 0.0156 0.0852
Brugia malayi Protein kinase domain containing protein 0.0446 0.143 0.1644
Trichomonas vaginalis CK1 family protein kinase 0.0198 0.0504 0.4592
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0179 0.0433 0.0607
Loa Loa (eye worm) hypothetical protein 0.0104 0.0152 0.0175
Onchocerca volvulus Glycogen phosphorylase homolog 0.013 0.0251 0.1378
Toxoplasma gondii aurora kinase 0.0159 0.0359 0.035
Schistosoma mansoni tyrosine kinase 0.0549 0.1812 0.2099
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0232 0.0632 0.0716
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0115 0.0194 0.0185
Schistosoma mansoni serine/threonine protein kinase 0.0347 0.1061 0.1228
Toxoplasma gondii histone kinase SNF1, putative 0.0104 0.0152 0.0143
Brugia malayi Egg laying defective protein 4 0.0148 0.0319 0.0354
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0216 0.057 0.0646
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0167 0.0389 0.045
Trichomonas vaginalis CMGC family protein kinase 0.0143 0.0297 0.2667
Brugia malayi metabotropic glutamate receptor type 2 0.035 0.1072 0.1229
Plasmodium falciparum serine/threonine protein kinase 0.0097 0.0129 0.012
Loa Loa (eye worm) TK/FER protein kinase 0.0105 0.0156 0.0179
Trypanosoma brucei aurora B kinase 0.0159 0.0359 0.0501
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0459 0.1477 0.1712
Loa Loa (eye worm) RGC/RGC protein kinase 0.0116 0.0196 0.0227
Brugia malayi Protein kinase domain containing protein 0.0947 0.3298 0.3814
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0237 0.0647 0.5916
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0111 0.0177 0.0188
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0127 0.0239 0.026
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0122 0.1052
Echinococcus multilocularis tyrosine kinase 0.0116 0.0196 0.021
Onchocerca volvulus 0.0337 0.1022 0.5621
Echinococcus granulosus dual specificity 0.0153 0.0335 0.0371
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0235 0.0642 0.0743
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0098 0.013 0.0149
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0127 0.0239 0.026
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.0152 0.1323
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0359 0.3242
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0136 0.0273 0.0378
Leishmania major protein kinase, putative 0.0167 0.0389 0.0544
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0167 0.0389 0.0544
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0244 0.0676 0.0767
Trichomonas vaginalis CAMK family protein kinase 0.0283 0.0819 0.7511
Schistosoma mansoni cell adhesion molecule 0.0116 0.0198 0.0227
Brugia malayi Protein kinase domain containing protein 0.0207 0.0537 0.0607
Loa Loa (eye worm) hypothetical protein 0.0085 0.0082 0.0093
Echinococcus granulosus tyrosine protein kinase Fyn 0.0232 0.0632 0.0716
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.0152 0.1323
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0127 0.0239 0.0329
Onchocerca volvulus 0.0111 0.0177 0.097
Echinococcus multilocularis casein kinase I alpha 0.0198 0.0504 0.0568
Giardia lamblia Kinase, CAMK CAMKL 0.0104 0.0152 0.1762
Giardia lamblia Kinase, CDC7 0.0104 0.0153 0.1778
Giardia lamblia Kinase, ULK 0.0109 0.0172 0.2017
Brugia malayi hypothetical protein 0.0111 0.0177 0.019
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0159 0.0359 0.0399
Schistosoma mansoni serine/threonine protein kinase 0.0214 0.0563 0.065
Loa Loa (eye worm) hypothetical protein 0.0068 0.0017 0.0018
Brugia malayi hypothetical protein 0.0235 0.0642 0.0729
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0224 0.0602 0.0849
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0405 0.1277 0.1465
Echinococcus multilocularis neuroglian 0.0104 0.0153 0.016
Echinococcus multilocularis cyclin g associated kinase 0.0189 0.047 0.0528
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.01 0.0139 0.0144
Echinococcus multilocularis serine threonine protein kinase 0.0264 0.0749 0.0853
Loa Loa (eye worm) hypothetical protein 0.0357 0.1096 0.127
Onchocerca volvulus 0.0143 0.0297 0.1628
Schistosoma mansoni protein kinase 0.0378 0.1175 0.1361
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0115 0.0194 0.0208
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0095 0.0121 0.0112
Mycobacterium tuberculosis Probable 1-deoxy-D-xylulose 5-phosphate reductoisomerase Dxr (DXP reductoisomerase) (1-deoxyxylulose-5-phosphate reductoisomeras 0.066 0.2226 1
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0122 0.1052
Trichomonas vaginalis AGC family protein kinase 0.0355 0.1088 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.0116 0.0196 0.0227
Trichomonas vaginalis STE family protein kinase 0.01 0.0139 0.1207
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0359 0.3242
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0068 0.0017 0.0002
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0444 0.1423 0.1635
Brugia malayi ephrin receptor 1 precursor 0.0078 0.0056 0.0049
Loa Loa (eye worm) hypothetical protein 0.0885 0.3066 0.3554
Echinococcus granulosus defective proboscis extension response 0.0083 0.0073 0.0067
Giardia lamblia Kinase, CMGC CK2 0.0114 0.0191 0.225
Echinococcus multilocularis c src tyrosine kinase 0.0145 0.0307 0.0339
Brugia malayi Protein kinase domain containing protein 0.0226 0.0609 0.0691
Echinococcus granulosus dual specificity 0.0136 0.0273 0.0299
Schistosoma mansoni serine/threonine protein kinase 0.0305 0.0904 0.1046
Trypanosoma brucei ABC1 protein, putative 0.0098 0.0132 0.0176
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0167 0.0389 0.0544
Trichomonas vaginalis CAMK family protein kinase 0.0129 0.0247 0.2202
Toxoplasma gondii AGC kinase 0.0127 0.0239 0.023
Entamoeba histolytica casein kinase, putative 0.0114 0.0191 0.1574
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.01 0.0139 0.0144
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0178 0.0427 0.0479
Trichomonas vaginalis CAMK family protein kinase 0.0283 0.0819 0.7511
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0391 0.1224 0.1404
Leishmania major protein kinase, putative 0.0096 0.0123 0.0163
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.017 0.04 0.0447
Giardia lamblia Kinase, CMGC CDK 0.0133 0.026 0.3101
Trypanosoma cruzi extracellular receptor, putative 0.0068 0.0017 0.0011
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0171 0.1502
Echinococcus multilocularis cyclin dependent kinase 1 0.0133 0.026 0.0285
Echinococcus multilocularis serine:threonine protein kinase N2 0.0128 0.0243 0.0265
Trichomonas vaginalis AGC family protein kinase 0.0118 0.0204 0.1808
Entamoeba histolytica protein kinase domain containing protein 0.0216 0.057 0.484
Onchocerca volvulus 0.0091 0.0103 0.0559
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0115 0.0194 0.0194
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.0191 0.169
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.0122 0.014
Echinococcus granulosus glycogen phosphorylase 0.013 0.0251 0.0274
Loa Loa (eye worm) hypothetical protein 0.0137 0.0277 0.032
Trichomonas vaginalis AGC family protein kinase 0.0223 0.0598 0.5464
Echinococcus granulosus serine threonine protein kinase nrc 0.017 0.04 0.0447
Schistosoma mansoni protein kinase 0.0206 0.0533 0.0616
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0232 0.0632 0.0716
Loa Loa (eye worm) TK protein kinase 0.0285 0.0829 0.096
Entamoeba histolytica protein kinase, putative 0.0143 0.0297 0.2484
Trypanosoma cruzi casein kinase, putative 0.0198 0.0504 0.0709
Trypanosoma cruzi ABC1 protein, putative 0.0098 0.0132 0.0176
Loa Loa (eye worm) hypothetical protein 0.0127 0.0239 0.0276
Giardia lamblia Kinase, AGC PKA 0.017 0.04 0.4824
Entamoeba histolytica protein kinase, putative 0.0153 0.0335 0.2812
Onchocerca volvulus 0.0105 0.0156 0.0852
Echinococcus granulosus serine:threonine protein kinase N2 0.0352 0.1077 0.1233
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.01 0.0139 0.0144
Echinococcus granulosus serine:threonine protein kinase N2 0.0128 0.0243 0.0265
Echinococcus granulosus Vam6:Vps39 protein 0.0111 0.0177 0.0188
Echinococcus granulosus raf serine:threonine protein kinase 0.0089 0.0099 0.0097
Echinococcus multilocularis 0.0167 0.0387 0.0432
Trypanosoma cruzi casein kinase, putative 0.0198 0.0504 0.0709
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0405 0.1277 0.1479
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0609 0.2036 0.236
Trichomonas vaginalis AGC family protein kinase 0.0118 0.0204 0.1808
Loa Loa (eye worm) hypothetical protein 0.0098 0.013 0.015
Schistosoma mansoni tyrosine kinase 0.0371 0.1148 0.1328
Giardia lamblia Kinase, AGC AKT 0.0216 0.0569 0.6913
Echinococcus multilocularis cyclin dependent kinase 0.0133 0.026 0.0285
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0069 0.0023 0.0026
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0158 0.0356 0.0396
Brugia malayi Skb1 methyltransferase family protein 0.0153 0.0336 0.0374
Loa Loa (eye worm) AGC/PKN protein kinase 0.0352 0.1077 0.1248
Schistosoma mansoni tyrosine kinase 0.0232 0.0632 0.073
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0245 0.0678 0.0785
Schistosoma mansoni atypical protein kinase C 0.0353 0.1081 0.1251
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0232 0.0632 0.0716
Schistosoma mansoni tyrosine kinase 0.0116 0.0196 0.0225
Echinococcus multilocularis glutamate receptor 2 0.0068 0.0017 0.0002
Entamoeba histolytica PH domain containing protein kinase, putative 0.0179 0.0433 0.3659
Brugia malayi protein unc-22 0.0085 0.0081 0.0078
Trichomonas vaginalis AGC family protein kinase 0.0118 0.0204 0.1808
Brugia malayi Protein kinase domain containing protein 0.0105 0.0156 0.0165
Trichomonas vaginalis AGC family protein kinase 0.0355 0.1088 1
Loa Loa (eye worm) hypothetical protein 0.0068 0.0017 0.0018
Schistosoma mansoni tyrosine kinase 0.0316 0.0944 0.1092
Schistosoma mansoni serine/threonine protein kinase 0.0266 0.0757 0.0876
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0136 0.0273 0.0378
Echinococcus multilocularis epidermal growth factor receptor 0.0607 0.203 0.234
Brugia malayi protein-tyrosine kinase 0.0192 0.048 0.0542
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0335 0.3019
Schistosoma mansoni rap gtpase-activating protein 0.0111 0.0177 0.0203
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0159 0.0359 0.0359
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0214 0.0563 0.0636
Echinococcus granulosus serine:threonine protein kinase 0.0128 0.0243 0.0264
Onchocerca volvulus 0.0104 0.0153 0.0838
Loa Loa (eye worm) hypothetical protein 0.0068 0.0017 0.0018
Echinococcus granulosus mitogen activated protein kinase 3 0.0098 0.0131 0.0134
Loa Loa (eye worm) hypothetical protein 0.0088 0.0094 0.0108
Loa Loa (eye worm) hypothetical protein 0.0184 0.0452 0.0523
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0104 0.0152 0.0159
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0115 0.0194 0.0194
Echinococcus multilocularis expressed conserved protein 0.0148 0.0319 0.0352
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0167 0.0387 0.0448
Loa Loa (eye worm) glutamate receptor 0.0283 0.082 0.0949
Entamoeba histolytica Skb1 methyltransferase, putative 0.0153 0.0336 0.282
Echinococcus granulosus tyrosine protein kinase 0.0285 0.0829 0.0945
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0391 0.1224 0.1418
Brugia malayi Fibronectin type III domain containing protein 0.0098 0.013 0.0135
Schistosoma mansoni kinase 0.0301 0.0887 0.1027
Echinococcus multilocularis casein kinase ii subunit alpha 0.0114 0.0191 0.0204
Plasmodium vivax ABC1 family, putative 0.0098 0.0132 0.0132
Trichomonas vaginalis CK1 family protein kinase 0.0198 0.0504 0.4592
Trichomonas vaginalis AGC family protein kinase 0.0159 0.0359 0.3242
Echinococcus multilocularis epidermal growth factor receptor 0.0401 0.1261 0.1447
Trichomonas vaginalis AGC family protein kinase 0.0118 0.0204 0.1808
Loa Loa (eye worm) hypothetical protein 0.0237 0.065 0.0752
Echinococcus granulosus serine:threonine protein kinase 3 0.0269 0.077 0.0876
Brugia malayi serine/threonine-protein kinase PAK 7 0.0245 0.0678 0.0772
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0199 0.0507 0.0587
Brugia malayi Protein kinase domain containing protein 0.0347 0.1061 0.1216
Entamoeba histolytica protein kinase, putative 0.0159 0.0359 0.3019
Schistosoma mansoni tyrosine kinase 0.0446 0.143 0.1656
Schistosoma mansoni serine/threonine protein kinase 0.0248 0.0689 0.0797
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0159 0.0359 0.3019
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.0099 0.0112
Entamoeba histolytica protein kinase, putative 0.0105 0.0155 0.1259
Onchocerca volvulus Poor gastrulation protein homolog 0.0117 0.02 0.1096
Entamoeba histolytica protein kinase domain containing protein 0.0136 0.0273 0.2279
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0097 0.0129 0.0171
Brugia malayi SH2 domain containing protein 0.0105 0.0156 0.0165
Brugia malayi Protein kinase domain containing protein 0.0285 0.0829 0.0947
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.015 0.0324 0.0324
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0111 0.0177 0.0203
Schistosoma mansoni serine/threonine protein kinase 0.0487 0.1582 0.1832
Echinococcus granulosus tyrosine protein kinase ABL1 0.031 0.0921 0.1052
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0127 0.0239 0.026
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0099 0.0134 0.1081
Loa Loa (eye worm) hypothetical protein 0.0142 0.0295 0.034
Toxoplasma gondii histone arginine methyltransferase PRMT5 0.0153 0.0336 0.0327
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0096 0.0123 0.0163
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0153 0.0335 0.0326
Echinococcus multilocularis serine:threonine protein kinase 38 0.0223 0.0598 0.0677
Toxoplasma gondii CMGC kinase, CK2 family 0.0114 0.0191 0.0182
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0378 0.1175 0.1347
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0104 0.0152 0.0204
Loa Loa (eye worm) hypothetical protein 0.0127 0.0237 0.0274
Trypanosoma cruzi cdc2-related kinase 3 0.0133 0.026 0.036
Entamoeba histolytica serine/threonine protein kinase, putative 0.0283 0.0819 0.6995
Onchocerca volvulus Tyrosine kinase homolog 0.055 0.1817 1
Echinococcus multilocularis casein kinase I delta 0.0198 0.0504 0.0568
Loa Loa (eye worm) hypothetical protein 0.0116 0.0196 0.0227
Brugia malayi Protein kinase domain containing protein 0.0096 0.0122 0.0126
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0098 0.0131 0.0174
Loa Loa (eye worm) AGC/PKA protein kinase 0.0127 0.0239 0.0276
Trypanosoma cruzi cdc2-related kinase 1 0.0133 0.026 0.036
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0214 0.0563 0.0651
Onchocerca volvulus 0.0068 0.0017 0.0087
Schistosoma mansoni tyrosine kinase 0.0145 0.0307 0.0354
Mycobacterium ulcerans 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.2743 1 1
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.01 0.0139 0.0144
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0116 0.0196 0.1076
Loa Loa (eye worm) AGC/PKG protein kinase 0.0148 0.0319 0.0368
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0171 0.1502
Schistosoma mansoni protein kinase 0.025 0.0697 0.0806
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0145 0.0307 0.0354
Echinococcus multilocularis hypothetical protein 0.0101 0.0141 0.0146
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0104 0.0152 0.0175
Schistosoma mansoni serine/threonine protein kinase 0.0226 0.0609 0.0704
Entamoeba histolytica protein kinase domain containing protein 0.0153 0.0335 0.2812
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0068 0.0017 0.0002
Trichomonas vaginalis CMGC family protein kinase 0.0114 0.0191 0.169
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0095 0.0121 0.0112
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0098 0.0131 0.0174
Schistosoma mansoni serine/threonine protein kinase 0.0178 0.0427 0.0493
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0159 0.0359 0.3019
Plasmodium vivax calcium-dependent protein kinase, putative 0.0115 0.0194 0.0194
Entamoeba histolytica protein kinase domain containing protein 0.0159 0.0359 0.3019
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0088 0.0094 0.0108
Echinococcus granulosus NCK adaptor protein 0.0097 0.0128 0.0131
Brugia malayi Protein kinase domain containing protein 0.019 0.0474 0.0535
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0159 0.0359 0.3019
Echinococcus multilocularis expressed protein 0.0097 0.0129 0.0132
Plasmodium vivax serine/threonine-protein kinase NEK4, putative 0.0065 0.0009 0.0009
Brugia malayi Protein kinase domain containing protein 0.0459 0.1477 0.1699
Plasmodium falciparum protein serine/threonine kinase-1 0.0167 0.0389 0.038
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0068 0.0017 0.0002
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.2374 0.8625 1
Trichomonas vaginalis AGC family protein kinase 0.0118 0.0204 0.1808
Loa Loa (eye worm) TK protein kinase 0.0135 0.0269 0.0311
Brugia malayi Metabotropic glutamate receptor precursor. 0.0719 0.2446 0.2825
Loa Loa (eye worm) TK/ALK protein kinase 0.0282 0.0817 0.0946
Mycobacterium leprae PROBABLE 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE DXR (DXP REDUCTOISOMERASE) (1-DEOXYXYLULOSE-5-PHOSPHATE REDUCTOISOMERAS 0.2743 1 1
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0111 0.0177 0.0203
Echinococcus multilocularis NCK adaptor protein 0.0099 0.0135 0.0139
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0504 0.1646 0.1894
Schistosoma mansoni metabotropic glutamate receptor 0.0602 0.2011 0.233
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.023 0.0623 0.0721
Entamoeba histolytica protein kinase, putative 0.0223 0.0598 0.5088
Schistosoma mansoni serine/threonine protein kinase 0.0085 0.0081 0.0092
Toxoplasma gondii ABC1 protein 0.0098 0.0132 0.0123
Schistosoma mansoni tyrosine kinase 0.0259 0.0732 0.0847
Leishmania major protein kinase, putative 0.0115 0.0194 0.0265
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0216 0.057 0.0659
Echinococcus granulosus casein kinase I alpha 0.0198 0.0504 0.0568
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0266 0.0757 0.0877
Brugia malayi Protein kinase domain containing protein 0.0178 0.0427 0.048
Trypanosoma brucei cdc2-related kinase 3 0.0133 0.026 0.036
Schistosoma mansoni serine/threonine protein kinase 0.0148 0.0319 0.0367
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.0152 0.1323
Leishmania major protein kinase, putative 0.0167 0.0389 0.0544
Schistosoma mansoni serine/threonine protein kinase 0.0069 0.0023 0.0025
Entamoeba histolytica protein kinase, putative 0.0159 0.0359 0.3019
Schistosoma mansoni protein kinase 0.0114 0.0191 0.0219
Echinococcus granulosus neuroglian 0.0104 0.0153 0.016
Trichomonas vaginalis AGC family protein kinase 0.015 0.0324 0.2922
Schistosoma mansoni serine/threonine protein kinase 0.0167 0.0389 0.0448
Brugia malayi casein kinase 1, delta 0.0198 0.0504 0.057
Echinococcus granulosus casein kinase I alpha 0.0198 0.0504 0.0568
Echinococcus multilocularis serine:threonine protein kinase 0.0128 0.0243 0.0264
Echinococcus multilocularis roundabout 2 0.0138 0.0278 0.0305
Echinococcus multilocularis mitogen activated protein kinase 14 0.1937 0.6992 0.8104
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.0152 0.1323
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0229 0.0619 0.0701
Loa Loa (eye worm) hypothetical protein 0.0456 0.1468 0.1701
Brugia malayi Protein kinase domain containing protein 0.0378 0.1175 0.1349
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0504 0.1646 0.1894
Entamoeba histolytica cell division protein kinase 2, putative 0.0133 0.026 0.2169
Echinococcus multilocularis Immunoglobulin 0.0083 0.0073 0.0067
Loa Loa (eye worm) hypothetical protein 0.0357 0.1096 0.127
Entamoeba histolytica casein kinase, putative 0.0198 0.0504 0.4276
Echinococcus granulosus tyrosine protein kinase Srms 0.0508 0.166 0.1911
Echinococcus granulosus serine:threonine protein kinase 0.0128 0.0243 0.0264
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.017 0.04 0.0391
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0171 0.1502
Loa Loa (eye worm) hypothetical protein 0.0119 0.021 0.0242
Echinococcus granulosus dual specificity 0.0153 0.0335 0.0371
Loa Loa (eye worm) glutamate receptor 0.0719 0.2446 0.2835
Toxoplasma gondii 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative 0.2743 1 1
Echinococcus multilocularis dual specificity protein kinase clk2 0.0167 0.0389 0.0434
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0143 0.0297 0.0343
Treponema pallidum 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.2743 1 0.5
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0085 0.0083 0.0079
Brugia malayi Temporarily assigned gene name protein 59 0.0111 0.0177 0.019
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0098 0.0131 0.0151
Echinococcus granulosus nervana 2 0.0122 0.0221 0.0239
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0103 0.0149 0.0172
Brugia malayi hypothetical protein 0.0098 0.013 0.0135
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0405 0.1275 0.1464
Entamoeba histolytica protein kinase, putative 0.0096 0.0122 0.098
Brugia malayi protein kinase C3,putative 0.0171 0.0404 0.0453
Echinococcus granulosus protein kinase c iota type 0.0347 0.1059 0.1212
Loa Loa (eye worm) hypothetical protein 0.0122 0.022 0.0254
Entamoeba histolytica protein kinase, putative 0.0085 0.0083 0.0641
Trichomonas vaginalis CAMK family protein kinase 0.0283 0.0819 0.7511
Trichomonas vaginalis CMGC family protein kinase 0.0143 0.0297 0.2667
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.007 0.0024 0.0011
Plasmodium falciparum serine/threonine protein kinase, putative 0.0159 0.0359 0.035
Trichomonas vaginalis CMGC family protein kinase 0.0133 0.026 0.2329
Echinococcus multilocularis receptor type guanylyl cyclase 0.0116 0.0196 0.021
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0602 0.2011 0.2318
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.0152 0.1323
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0143 0.0297 0.0327
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0172 0.0198
Entamoeba histolytica PH domain containing protein kinase, putative 0.0179 0.0433 0.3659
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0171 0.1502
Entamoeba histolytica protein kinase, putative 0.0088 0.0092 0.0718
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0947 0.3298 0.3823
Echinococcus granulosus insulin receptor 0.0446 0.143 0.1643
Schistosoma mansoni hypothetical protein 0.0111 0.0177 0.0203
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0122 0.0221 0.0239
Schistosoma mansoni tyrosine kinase 0.0088 0.0092 0.0104
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.1937 0.6992 1
Loa Loa (eye worm) TK/FER protein kinase 0.0105 0.0156 0.0179
Loa Loa (eye worm) RGC/RGC protein kinase 0.0116 0.0196 0.0227
Brugia malayi probable protein kinase 0.0277 0.0799 0.0912
Echinococcus multilocularis glycogen phosphorylase 0.013 0.0251 0.0274
Echinococcus granulosus GPCR family 3 C terminal 0.0117 0.02 0.0215
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0136 0.0273 0.0378
Echinococcus multilocularis Immunoglobulin 0.0083 0.0073 0.0067
Trichomonas vaginalis CAMK family protein kinase 0.0115 0.0194 0.1715
Loa Loa (eye worm) AGC/PKA protein kinase 0.0127 0.0239 0.0276
Brugia malayi Guanylyl cyclase protein 23 0.0116 0.0196 0.0212
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0364 0.1123 0.6178
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0216 0.057 0.0644
Echinococcus granulosus growth factor receptor bound protein 2 0.0099 0.0135 0.0139
Plasmodium vivax serine/threonine-protein kinase Nek1, putative 0.0065 0.0009 0.0009
Schistosoma mansoni serine/threonine protein kinase 0.0104 0.0152 0.0174
Brugia malayi Protein kinase domain containing protein 0.0097 0.0129 0.0133
Schistosoma mansoni serine/threonine protein kinase 0.0248 0.0689 0.0797
Echinococcus granulosus glycogen phosphorylase 0.013 0.0251 0.0274
Echinococcus granulosus N chimaerin 0.0098 0.013 0.0134
Schistosoma mansoni serine/threonine kinase 0.0223 0.0598 0.0692
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0284 0.0826 0.0957
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0143 0.0297 0.0412
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0329 0.0994 0.1151
Brugia malayi Protein kinase domain containing protein 0.0104 0.0153 0.0162
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0115 0.0194 0.0265
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0069 0.0023 0.0026
Onchocerca volvulus 0.0289 0.0843 0.4636
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0068 0.0017 0.0002
Echinococcus multilocularis protein kinase c iota type 0.0347 0.1059 0.1212
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0405 0.1275 0.1464
Entamoeba histolytica protein kinase domain containing protein 0.0096 0.0123 0.0985
Trichomonas vaginalis AGC family protein kinase 0.0118 0.0204 0.1808
Schistosoma mansoni serine/threonine protein kinase 0.0405 0.1277 0.1478
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0609 0.2036 0.236
Brugia malayi Protein kinase domain containing protein 0.0214 0.0563 0.0638
Entamoeba histolytica protein kinase, putative 0.0355 0.1088 0.9313
Echinococcus granulosus NDR protein kinase 0.0223 0.0598 0.0677
Brugia malayi map kinase activated protein kinase protein 2 0.0405 0.1277 0.1467
Loa Loa (eye worm) hypothetical protein 0.0081 0.0065 0.0075
Entamoeba histolytica hypothetical protein 0.0068 0.0017 0.0068
Echinococcus multilocularis c Jun NH2 terminal kinase 0.2374 0.8625 1
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0109 0.0172 0.0234
Loa Loa (eye worm) casein kinase 0.0178 0.043 0.0498
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0111 0.0177 0.0241
Onchocerca volvulus 0.0191 0.0479 0.2633
Brugia malayi putative serine/threonine kinase SADA gamma 0.0104 0.0152 0.016
Loa Loa (eye worm) hypothetical protein 0.0111 0.0177 0.0204
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0216 0.057 0.0644
Onchocerca volvulus 0.048 0.1557 0.857
Echinococcus granulosus serine:threonine protein kinase NLK 0.0347 0.1061 0.1214
Echinococcus granulosus protein tyrosine kinase 0.0549 0.1812 0.2087
Trypanosoma brucei protein kinase, putative 0.0096 0.0123 0.0163
Trypanosoma cruzi ULK family serine/threonine-protein kinase, putative 0.0109 0.0172 0.0234
Loa Loa (eye worm) hypothetical protein 0.0098 0.013 0.015
Loa Loa (eye worm) hypothetical protein 0.0105 0.0156 0.0179
Plasmodium falciparum cGMP-dependent protein kinase 0.0148 0.0319 0.031
Echinococcus multilocularis tyrosine protein kinase ABL1 0.031 0.0921 0.1052
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0115 0.0194 0.0208
Leishmania major arginine N-methyltransferase, type II, putative;with=GeneDB:Tb927.10.640 0.0098 0.013 0.0174
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.1937 0.6992 1
Schistosoma mansoni protein kinase 0.0096 0.0123 0.014
Loa Loa (eye worm) TK/FER protein kinase 0.0105 0.0156 0.0179
Entamoeba histolytica glycogen phosphorylase, putative 0.013 0.0251 0.2091
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0099 0.0134 0.1081
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0083 0.0073 0.0067
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0146 0.0308 0.034
Plasmodium vivax serine/threonine kinase-1, putative 0.0167 0.0389 0.0389
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0409 0.1292 0.1483
Brugia malayi Protein kinase domain 0.01 0.0139 0.0146
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0127 0.0239 0.026
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0111 0.0177 0.0188
Trichomonas vaginalis AGC family protein kinase 0.0118 0.0204 0.1808
Schistosoma mansoni serine/threonine-protein kinase 0.0179 0.0433 0.05
Echinococcus granulosus dual specificity testis-specific protein kinase 0.025 0.0697 0.0792
Echinococcus multilocularis glycogen phosphorylase 0.013 0.0251 0.0274
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.007 0.0024 0.0011
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0136 0.0273 0.0378
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0335 0.3019
Brugia malayi Sex muscle abnormal protein 5 0.0097 0.0128 0.0132
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0085 0.0083 0.0079
Loa Loa (eye worm) hypothetical protein 0.0115 0.0194 0.0224
Echinococcus granulosus metabotropic glutamate receptor 5 0.0885 0.3066 0.3543
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0133 0.026 0.0301
Echinococcus granulosus tyrosine protein kinase Src42A 0.0146 0.0308 0.034
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0232 0.0632 0.0716
Plasmodium falciparum calcium-dependent protein kinase 4 0.0115 0.0194 0.0185
Giardia lamblia Kinase, STE STE20 0.01 0.0139 0.1608
Echinococcus multilocularis glutamate receptor 2 0.0068 0.0017 0.0002
Trichomonas vaginalis CAMK family protein kinase 0.0283 0.0819 0.7511
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0085 0.0083 0.0079
Loa Loa (eye worm) hypothetical protein 0.0083 0.0073 0.0083
Plasmodium vivax protein arginine N-methyltransferase 5, putative 0.0153 0.0336 0.0336
Schistosoma mansoni tyrosine kinase 0.0244 0.0676 0.0782
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0231 0.0625 0.071
Brugia malayi Immunoglobulin I-set domain containing protein 0.0085 0.0081 0.0078
Giardia lamblia Kinase, CMGC GSK 0.0143 0.0297 0.355
Leishmania major protein kinase A catalytic subunit isoform 1 0.0127 0.0239 0.0329
Schistosoma mansoni tyrosine kinase 0.0353 0.1082 0.1252
Brugia malayi serine/threonine-protein kinase 6 0.0159 0.0359 0.0401
Leishmania major ABC1 protein, putative 0.0098 0.0132 0.0176
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0216 0.0569 0.0645
Echinococcus granulosus serine:threonine kinase SAD 1 0.0104 0.0152 0.0159
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0131 0.1129
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0079 0.006 0.0052
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0099 0.0134 0.0179
Schistosoma mansoni tyrosine kinase 0.0253 0.071 0.0821
Plasmodium falciparum protein arginine N-methyltransferase 5, putative 0.0153 0.0336 0.0327
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0098 0.013 0.0149
Onchocerca volvulus 0.0137 0.0277 0.1519
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0364 0.1123 0.1301
Plasmodium vivax protein kinase Crk2 0.0133 0.026 0.026
Trichomonas vaginalis CK1 family protein kinase 0.0198 0.0504 0.4592
Loa Loa (eye worm) TK/EPH protein kinase 0.0129 0.0245 0.0283
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0178 0.0427 0.0494
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0115 0.0194 0.0209
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0159 0.0359 0.0399
Echinococcus granulosus Immunoglobulin 0.0083 0.0073 0.0067
Schistosoma mansoni ABC transporter 0.0098 0.0132 0.015
Plasmodium falciparum 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.2743 1 1
Loa Loa (eye worm) hypothetical protein 0.0117 0.02 0.0231
Loa Loa (eye worm) hypothetical protein 0.0183 0.0446 0.0516
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0199 0.0507 0.0572
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0098 0.0131 0.0174
Schistosoma mansoni serine/threonine protein kinase 0.0352 0.1077 0.1246
Trypanosoma brucei polo-like protein kinase 0.0283 0.0819 0.116
Schistosoma mansoni serine/threonine protein kinase 0.0153 0.0335 0.0386
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0269 0.077 0.0891
Brugia malayi Protein kinase domain containing protein 0.0609 0.2036 0.2349
Trypanosoma brucei protein kinase, putative 0.0098 0.0131 0.0174
Echinococcus granulosus Protein kinase C brain isozyme 0.0305 0.0904 0.1032
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0444 0.1423 0.1635
Brugia malayi P38 map kinase family protein 2 0.1937 0.6992 0.8104
Schistosoma mansoni hypothetical protein 0.0101 0.0141 0.0161
Entamoeba histolytica glycogen phosphorylase, putative 0.013 0.0251 0.2091
Trichomonas vaginalis serine/threonine-protein kinase, putative 0.0109 0.0171 0.1502
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0115 0.0194 0.0185
Schistosoma mansoni serine/threonine protein kinase 0.0235 0.0642 0.0742
Brugia malayi STE20-like kinase MST 0.0269 0.077 0.0878
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0462 0.1487 0.171
Plasmodium falciparum calcium-dependent protein kinase 5 0.0115 0.0194 0.0185
Schistosoma mansoni titin 0.0085 0.0081 0.0092
Loa Loa (eye worm) TK/INSR protein kinase 0.0446 0.143 0.1657
Loa Loa (eye worm) hypothetical protein 0.0609 0.2036 0.236
Trypanosoma cruzi Wee1-like protein kinase, putative 0.0104 0.0153 0.0206
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0364 0.1123 0.1287
Onchocerca volvulus 0.0105 0.0156 0.0852
Giardia lamblia Kinase, CK1 Casein kinase 0.0198 0.0504 0.6114
Echinococcus granulosus fibroblast growth factor receptor 4 0.0244 0.0676 0.0767
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0171 0.1502
Echinococcus multilocularis 0.0119 0.021 0.0226
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0214 0.0563 0.0636
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0133 0.026 0.036
Loa Loa (eye worm) TK/FER protein kinase 0.0105 0.0156 0.0179
Loa Loa (eye worm) CDC7 protein kinase 0.0104 0.0153 0.0176
Entamoeba histolytica protein kinase, putative 0.0355 0.1088 0.9313
Schistosoma mansoni protein kinase 0.01 0.0139 0.0159
Echinococcus multilocularis titin 0.0085 0.0081 0.0077
Loa Loa (eye worm) hypothetical protein 0.0111 0.0177 0.0204
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.0152 0.1323
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0096 0.0123 0.0163
Trypanosoma cruzi aurora B kinase, putative 0.0159 0.0359 0.0501
Echinococcus granulosus twitchin 0.0152 0.0331 0.0367
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.0117 0.02 0.1096
Echinococcus granulosus tyrosine protein kinase Fyn 0.0232 0.0632 0.0716
Echinococcus granulosus CDC7 cell division cycle 7 0.0104 0.0153 0.016
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0114 0.0191 0.0191
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0159 0.0356 0.0396
Schistosoma mansoni serine/threonine protein kinase 0.0149 0.0319 0.0368
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.1937 0.6992 1
Schistosoma mansoni protein kinase 0.025 0.0697 0.0806
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0098 0.0131 0.0174
Plasmodium falciparum calcium-dependent protein kinase 3 0.0115 0.0194 0.0185
Loa Loa (eye worm) hypothetical protein 0.0098 0.013 0.015
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.01 0.0139 0.0144
Echinococcus multilocularis 0.0172 0.0406 0.0453
Schistosoma mansoni protein kinase 0.01 0.0139 0.0159
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0158 0.0356 0.0396
Schistosoma mansoni serine/threonine protein kinase 0.0133 0.026 0.0299
Wolbachia endosymbiont of Brugia malayi 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.2743 1 0.5
Echinococcus granulosus Glycosyl transferase family 35 0.013 0.0251 0.0274
Schistosoma mansoni tyrosine kinase 0.0232 0.0632 0.073
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0104 0.0153 0.0206
Plasmodium vivax tyrosine kinase-like protein, putative 0.0095 0.0121 0.0121
Entamoeba histolytica hypothetical protein 0.0136 0.0273 0.2279
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0104 0.0152 0.0204
Entamoeba histolytica protein kinase, putative 0.0136 0.0273 0.2279
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0184 0.0452 0.0523
Onchocerca volvulus 0.0085 0.0081 0.0442
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0462 0.1487 0.171
Echinococcus granulosus glutamate receptor 2 0.0068 0.0017 0.0002
Echinococcus granulosus tyrosine kinase 0.0105 0.0156 0.0163
Giardia lamblia Kinase, CMGC CDK 0.0133 0.026 0.3101
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0096 0.0122 0.0141
Echinococcus granulosus cyclin dependent kinase 0.0133 0.026 0.0285
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0143 0.0297 0.0327
Onchocerca volvulus 0.0105 0.0156 0.0852
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.017 0.04 0.0447
Schistosoma mansoni tyrosine kinase 0.0401 0.1261 0.146
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0405 0.1277 0.1465
Loa Loa (eye worm) TK/FER protein kinase 0.0105 0.0156 0.0179
Schistosoma mansoni tyrosine kinase 0.0079 0.006 0.0067
Entamoeba histolytica protein kinase, putative 0.0116 0.0199 0.1637
Brugia malayi Protein kinase domain containing protein 0.0128 0.0243 0.0266
Loa Loa (eye worm) hypothetical protein 0.0191 0.0479 0.0555
Schistosoma mansoni protein kinase C mu 0.0231 0.0625 0.0722
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0097 0.0128 0.0147
Echinococcus granulosus cyclin g associated kinase 0.0189 0.047 0.0528
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0171 0.1502
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0068 0.0017 0.0018
Trichomonas vaginalis AGC family protein kinase 0.0109 0.0171 0.1502
Leishmania major protein kinase, putative 0.0099 0.0134 0.0179
Loa Loa (eye worm) hypothetical protein 0.0229 0.0621 0.0719
Echinococcus multilocularis calcium activated potassium channel 0.0149 0.0319 0.0353
Giardia lamblia Kinase, NEK 0.015 0.0324 0.3891
Brugia malayi intracellular kinase 0.0143 0.0297 0.0329
Brugia malayi RhoGAP domain containing protein 0.0098 0.013 0.0136
Trichomonas vaginalis AGC family protein kinase 0.0118 0.0204 0.1808
Trichomonas vaginalis AGC family protein kinase 0.0118 0.0204 0.1808
Schistosoma mansoni tyrosine kinase 0.0145 0.0307 0.0354
Echinococcus granulosus calcium activated potassium channel 0.0149 0.0319 0.0353
Trypanosoma cruzi Wee1-like protein kinase, putative 0.0104 0.0153 0.0206

Activities

Activity type Activity value Assay description Source Reference
Log Ki (binding) = 2.47 pKi value expresses binding affinity against thermolysin pKi = -logKi (where Ki is in mol/L) ChEMBL. 11931613

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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