Detailed information for compound 712065

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 431.303 | Formula: C19H15BrN2O3S
  • H donors: 1 H acceptors: 3 LogP: 3.95 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(C(N1c2cccc3c2c(S1(=O)=O)ccc3)C)Nc1ccccc1Br
  • InChi: 1S/C19H15BrN2O3S/c1-12(19(23)21-15-9-3-2-8-14(15)20)22-16-10-4-6-13-7-5-11-17(18(13)16)26(22,24)25/h2-12H,1H3,(H,21,23)
  • InChiKey: AIDINPFWWZLQCB-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis CAMK family protein kinase 0.029 0.051 0.0501
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0057 0.0638
Loa Loa (eye worm) hypothetical protein 0.0047 0.0057 0.0056
Schistosoma mansoni hypothetical protein 0.0174 0.0295 0.0295
Toxoplasma gondii hypothetical protein 0.0054 0.0071 0.0081
Mycobacterium tuberculosis Conserved protein 0.0075 0.0111 0.1019
Schistosoma mansoni hypothetical protein 0.0082 0.0124 0.0124
Echinococcus granulosus serine protein kinase ATM 0.102 0.1868 0.1867
Echinococcus multilocularis peregrin 0.0038 0.0041 0.004
Onchocerca volvulus 0.0075 0.0111 0.0108
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0031 0.0029 0.0027
Echinococcus granulosus chromobox protein 1 0.0076 0.0112 0.0111
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0067 0.0095 0.0095
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0061 0.0085 0.0084
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0055 0.0046
Plasmodium vivax hypothetical protein 0.0348 0.0618 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0036 0.0037 0.0035
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0039 0.003
Leishmania major phosphatidylinositol kinase related protein, putative 0.0348 0.0618 0.0618
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0047 0.0057 0.0638
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0136 0.0223 0.0222
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.102 0.1868 0.1867
Loa Loa (eye worm) hypothetical protein 0.0619 0.1121 0.112
Trypanosoma cruzi polo-like protein kinase, putative 0.029 0.051 0.0509
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0053 0.007 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0672 0.1221 0.1212
Loa Loa (eye worm) hypothetical protein 0.0033 0.0033 0.0032
Echinococcus granulosus histone acetyltransferase MYST2 0.0052 0.0068 0.0067
Schistosoma mansoni DNA ligase IV 0.003 0.0028 0.0027
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0348 0.0618 0.0618
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0028 0.0018
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0067 0.0095 0.0094
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0158 0.0266 0.0265
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0348 0.0618 0.0617
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0148 0.0246 0.0244
Trypanosoma brucei heat shock protein, putative 0.0034 0.0034 0.0033
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.5394 1 1
Plasmodium vivax SET domain protein, putative 0.0036 0.0037 0.0547
Trichomonas vaginalis helicase, putative 0.0027 0.0021 0.0011
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.1809 0.3334 0.3333
Schistosoma mansoni hypothetical protein 0.0789 0.1437 0.1437
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0067 0.0095 0.0094
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0348 0.0618 0.0617
Trichomonas vaginalis PIKK family atypical protein kinase 0.1809 0.3334 0.3328
Brugia malayi acetyltransferase, GNAT family protein 0.0148 0.0246 0.0245
Loa Loa (eye worm) endoplasmin 0.0034 0.0034 0.0032
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0348 0.0618 0.0609
Trichomonas vaginalis PIKK family atypical protein kinase 0.4012 0.743 0.7428
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0031 0.0029 0.0027
Giardia lamblia Heat shock protein HSP 90-alpha 0.0027 0.0021 0.001
Mycobacterium tuberculosis Probable esterase LipL 0.0075 0.0111 0.1019
Echinococcus multilocularis replication factor c subunit 1 0.003 0.0028 0.0026
Onchocerca volvulus Epoxide hydrolase 1 homolog 0.4146 0.7681 1
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0348 0.0618 0.0617
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0348 0.0618 0.0617
Brugia malayi hypothetical protein 0.0036 0.0038 0.0037
Loa Loa (eye worm) MBOAT family protein 0.0067 0.0095 0.0094
Schistosoma mansoni endoplasmin 0.0034 0.0034 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.1809 0.3334 0.3328
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0052 0.0068 0.0067
Echinococcus granulosus peregrin 0.0038 0.0041 0.004
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0044 0.0043
Leishmania major heat shock protein 83-1 0.0034 0.0034 0.0033
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0004 0.0003
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0022 0.0022
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0031 0.0029 0.0028
Trichomonas vaginalis CAMK family protein kinase 0.0144 0.0238 0.0229
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0067 0.0095 0.0095
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0075 0.0111 0.1019
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0039 0.0044 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0029 0.0027
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0348 0.0618 1
Leishmania major fk506-binding protein 1-like protein 0.0061 0.0085 0.0084
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0105 0.0165 0.0164
Brugia malayi TAR-binding protein 0.0257 0.0448 0.0447
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.0111 0.0101
Mycobacterium ulcerans heat shock protein 90 0.0027 0.0021 0.0232
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0672 0.1221 0.122
Schistosoma mansoni microtubule-associated protein tau 0.2112 0.3898 0.3898
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0061 0.0085 0.0084
Trichomonas vaginalis porcupine, putative 0.0067 0.0095 0.0086
Loa Loa (eye worm) hypothetical protein 0.0055 0.0072 0.0071
Onchocerca volvulus 0.0056 0.0075 0.0062
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0035 0.0036 1
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.1809 0.3334 0.3334
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0029 0.0027
Brugia malayi DKFZp564C0469 protein 0.003 0.0028 0.0026
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0044 0.0034
Brugia malayi RNA binding protein 0.0257 0.0448 0.0447
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.102 0.1868 0.1867
Trichomonas vaginalis chromobox protein, putative 0.0046 0.0056 0.0047
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0067 0.0095 0.0094
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0031 0.0029 0.0027
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0104 0.0165 0.0163
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0004 0.0003
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0257 0.0448 0.0447
Loa Loa (eye worm) hypothetical protein 0.0043 0.005 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0028 0.0018
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0011 0.001
Echinococcus granulosus tar DNA binding protein 0.0257 0.0448 0.0447
Echinococcus multilocularis endoplasmin 0.0027 0.0021 0.002
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0047 0.0058 0.0058
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0029 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.2912 0.5386 0.5382
Echinococcus granulosus serine/threonine protein kinase 0.0025 0.0018 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0028 0.0018
Schistosoma mansoni tar DNA-binding protein 0.0257 0.0448 0.0448
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0348 0.0618 1
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0348 0.0618 1
Onchocerca volvulus 0.0118 0.019 0.0213
Trichomonas vaginalis PIKK family atypical protein kinase 0.1447 0.2662 0.2655
Entamoeba histolytica PH domain containing protein kinase, putative 0.0025 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0067 0.0095 0.0094
Schistosoma mansoni tar DNA-binding protein 0.0257 0.0448 0.0448
Echinococcus multilocularis nervana 2 0.0022 0.0012 0.001
Leishmania major phosphatidylinositol 3-related kinase, putative 0.1809 0.3334 0.3334
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0348 0.0618 0.0618
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0031 0.0029 0.0027
Loa Loa (eye worm) MBOAT family protein 0.0067 0.0095 0.0094
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.003 0.0029
Trypanosoma cruzi heat shock protein 85, putative 0.0034 0.0034 0.0033
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0032 0.0127
Echinococcus granulosus beta LACTamase domain containing family member 0.0075 0.0111 0.0109
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0011 0.001
Leishmania major heat shock protein 83-1 0.0034 0.0034 0.0033
Loa Loa (eye worm) CHromoDomain protein family member 0.0021 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0035 0.0036 0.0034
Loa Loa (eye worm) hypothetical protein 0.0053 0.0069 0.0068
Echinococcus multilocularis PHD finger protein rhinoceros 0.0032 0.003 0.0029
Schistosoma mansoni tar DNA-binding protein 0.0257 0.0448 0.0448
Leishmania major heat shock protein 83-1 0.0034 0.0034 0.0033
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0067 0.0095 0.1495
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0055 0.0836
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.5394 1 1
Onchocerca volvulus 0.0056 0.0075 0.0062
Loa Loa (eye worm) hhat protein 0.0067 0.0095 0.0094
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0348 0.0618 0.0618
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0348 0.0618 0.0618
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0057 0.0613
Loa Loa (eye worm) hypothetical protein 0.0075 0.0111 0.0109
Onchocerca volvulus 0.0348 0.0618 0.0771
Echinococcus granulosus expressed conserved protein 0.0187 0.0319 0.0317
Mycobacterium tuberculosis Conserved hypothetical protein 0.0176 0.0299 0.316
Loa Loa (eye worm) heat shock protein 90 0.0034 0.0034 0.0032
Trichomonas vaginalis heat shock protein, putative 0.0027 0.0021 0.0011
Echinococcus multilocularis nervana 2 0.0022 0.0012 0.001
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.029 0.051 0.0509
Echinococcus granulosus Niemann Pick C1 protein 0.0199 0.0341 0.034
Echinococcus granulosus heat shock protein 90 0.0027 0.0021 0.002
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0129 0.0211 0.2164
Schistosoma mansoni zinc finger protein 0.0031 0.0028 0.0027
Brugia malayi diacylglycerol acyltransferase 0.0067 0.0095 0.0094
Loa Loa (eye worm) hypothetical protein 0.0046 0.0056 0.0055
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0348 0.0618 0.0618
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0029 0.0027
Brugia malayi hypothetical protein 0.0038 0.0041 0.004
Leishmania major heat shock protein 83-1 0.0034 0.0034 0.0033
Trypanosoma brucei Heat shock protein 83, putative 0.0034 0.0034 0.0033
Echinococcus multilocularis musashi 0.0056 0.0075 0.0074
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0053 0.0069 0.0068
Entamoeba histolytica hypothetical protein 0.0348 0.0618 0.0618
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0348 0.0618 0.0618
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0023 0.0014 0.0219
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.0006 0.0005
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0348 0.0618 0.0618
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0031 0.0029 0.0027
Entamoeba histolytica protein kinase, putative 0.0037 0.0039 0.0038
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0348 0.0618 0.0617
Trichomonas vaginalis PIKK family atypical protein kinase 0.0672 0.1221 0.1212
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0039 0.003
Trichomonas vaginalis transmembrane protein nessy, putative 0.0067 0.0095 0.0086
Echinococcus granulosus heat shock protein 90 0.0034 0.0034 0.0032
Trichomonas vaginalis heat shock protein, putative 0.0027 0.0021 0.0011
Loa Loa (eye worm) hypothetical protein 0.0056 0.0075 0.0074
Brugia malayi ecdysteroid receptor 0.0031 0.0029 0.0027
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0057 0.0056
Schistosoma mansoni cpg binding protein 0.0127 0.0206 0.0206
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.0111 0.0101
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.102 0.1868 0.1867
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0348 0.0618 0.0617
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0031 0.0028 0.0026
Leishmania major heat shock protein 83-1 0.0034 0.0034 0.0033
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0348 0.0618 0.0609
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0031 0.0029 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0021 0.0011
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.102 0.1868 0.1867
Echinococcus granulosus lamin dm0 0.0056 0.0075 0.0074
Leishmania major hypothetical protein, unknown function 0.0348 0.0618 0.0618
Schistosoma mansoni hypothetical protein 0.0081 0.0121 0.012
Leishmania major heat shock protein 83-1 0.0034 0.0034 0.0033
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.4295 0.7956 0.7956
Loa Loa (eye worm) hypothetical protein 0.0348 0.0618 0.0617
Brugia malayi Intermediate filament tail domain containing protein 0.0056 0.0075 0.0074
Brugia malayi F/Y-rich N-terminus family protein 0.005 0.0063 0.0062
Brugia malayi hypothetical protein 0.003 0.0028 0.0026
Echinococcus multilocularis nibrin 0.003 0.0028 0.0026
Echinococcus granulosus intermediate filament protein 0.0056 0.0075 0.0074
Leishmania major heat shock protein 83-1 0.0034 0.0034 0.0033
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0021 0.001 0.001
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.2551 0.4714 0.4714
Schistosoma mansoni endoplasmin 0.0034 0.0034 0.0033
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0057 0.0056
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0085 0.013 0.0128
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0028 0.0027
Loa Loa (eye worm) hypothetical protein 0.0055 0.0072 0.0071
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0057 0.0638
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0057 0.0638
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0061 0.0085 0.0084
Echinococcus granulosus zinc finger protein 0.0031 0.0028 0.0026
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0136 0.0223 0.0222
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.0011 0.0172
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0053 0.0069 0.0068
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0041 0.004
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0095 0.0086
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0348 0.0618 0.0618
Entamoeba histolytica recQ family helicase, putative 0.0022 0.0011 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.4012 0.743 0.7428
Trichomonas vaginalis PIKK family atypical protein kinase 0.3191 0.5904 0.59
Brugia malayi Protein kinase domain containing protein 0.0037 0.0039 0.0038
Entamoeba histolytica heat shock protein 90, putative 0.0034 0.0034 0.0033
Onchocerca volvulus 0.0265 0.0464 0.057
Mycobacterium ulcerans hypothetical protein 0.0075 0.0111 0.1228
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0022 0.03
Echinococcus granulosus tumor protein p63 0.0337 0.0597 0.0596
Brugia malayi FAT domain containing protein 0.0789 0.1437 0.1436
Brugia malayi hypothetical protein 0.0027 0.0022 0.0021
Leishmania major heat shock protein 83-1 0.0034 0.0034 0.0033
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0348 0.0618 0.0617
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0011 0.0002
Echinococcus granulosus serine:threonine protein kinase SMG1 0.102 0.1868 0.1867
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0022 0.0015
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0067 0.0095 0.0094
Trichomonas vaginalis penicillin-binding protein, putative 0.0075 0.0111 0.0101
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0038 0.0041 0.004
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0348 0.0618 0.0618
Plasmodium vivax acyl-CoA synthetase, putative 0.0035 0.0036 0.052
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0011 0.0011
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0348 0.0618 0.0617
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0021 0.001 0.0009
Leishmania major phosphatidylinositol 3-kinase, putative 0.0348 0.0618 0.0618
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0055 0.0059
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.5394 1 1
Toxoplasma gondii FATC domain-containing protein 0.102 0.1868 0.2503
Entamoeba histolytica PH domain containing protein kinase, putative 0.0025 0.0018 0.0018
Loa Loa (eye worm) transcription factor SMAD2 0.0115 0.0185 0.0184
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0061 0.0085 0.0084
Echinococcus multilocularis SAM and MBT domain containing protein 0.0046 0.0057 0.0055
Echinococcus multilocularis beta LACTamase domain containing family member 0.0075 0.0111 0.0109
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0047 0.0058 0.0058
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0029 0.0028
Brugia malayi chromobox protein homolog 3 0.0043 0.005 0.0049
Echinococcus granulosus serine threonine protein kinase nrc 0.0023 0.0014 0.0013
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0031 0.0029 0.0027
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0158 0.0266 0.0265
Loa Loa (eye worm) PHD-finger family protein 0.0032 0.003 0.0029
Entamoeba histolytica acyl-coA synthetase, putative 0.0047 0.0057 0.0057
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0029 0.0027
Echinococcus multilocularis heat shock protein 90 0.0034 0.0034 0.0032
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0053 0.007 0.007
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.004 0.0045 0.0044
Schistosoma mansoni hypothetical protein 0.0081 0.0121 0.012
Toxoplasma gondii histone lysine methyltransferase SET1 0.0231 0.04 0.0524
Trichomonas vaginalis PIKK family atypical protein kinase 0.1809 0.3334 0.3328
Trichomonas vaginalis esterase, putative 0.0075 0.0111 0.0101
Leishmania major phosphatidylinositol 4-kinase, putative 0.0348 0.0618 0.0618
Loa Loa (eye worm) hypothetical protein 0.0035 0.0036 0.0034
Brugia malayi nuclear hormone receptor 0.0031 0.0029 0.0027
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0022 0.0011 0.001
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.0111 0.0101
Loa Loa (eye worm) hypothetical protein 0.0046 0.0057 0.0055
Plasmodium vivax heat shock protein 86, putative 0.0034 0.0034 0.0489
Echinococcus multilocularis lamin dm0 0.0056 0.0075 0.0074
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0021 0.001 0.0009
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0047 0.0058 0.0058
Entamoeba histolytica heat shock protein 90, putative 0.0034 0.0034 0.0033
Schistosoma mansoni hypothetical protein 0.0067 0.0095 0.0095
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0348 0.0618 0.0818
Echinococcus granulosus SAM and MBT domain containing protein 0.0046 0.0057 0.0055
Mycobacterium ulcerans hypothetical protein 0.0047 0.0057 0.0638
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0032 0.003 0.003
Plasmodium vivax replication factor C subunit 1, putative 0.003 0.0028 0.039
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0029 0.0027
Schistosoma mansoni topbp1 0.003 0.0028 0.0027
Echinococcus granulosus FTZ F1 alpha 0.0031 0.0029 0.0027
Onchocerca volvulus 0.0049 0.0063 0.0046
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0067 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0049 0.0063 0.0061
Echinococcus granulosus neuropeptide s receptor 0.0993 0.1817 0.1816
Leishmania major heat shock protein 83-1 0.0034 0.0034 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.4012 0.743 0.7428
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0072 0.0105 0.0104
Echinococcus multilocularis GPCR, family 2 0.0081 0.0121 0.012
Loa Loa (eye worm) hypothetical protein 0.0075 0.0111 0.0109
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0039 0.003
Brugia malayi latrophilin 2 splice variant baaae 0.0174 0.0295 0.0294
Trichomonas vaginalis PIKK family atypical protein kinase 0.3191 0.5904 0.59
Trypanosoma brucei heat shock protein, putative 0.0034 0.0034 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.2912 0.5386 0.5382
Echinococcus multilocularis geminin 0.1024 0.1874 0.1873
Schistosoma mansoni hypothetical protein 0.0021 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0021
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.1809 0.3334 0.3334
Loa Loa (eye worm) hypothetical protein 0.0055 0.0073 0.0072
Echinococcus multilocularis thyroid hormone receptor alpha 0.0031 0.0029 0.0027
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0031 0.0029 0.0027
Loa Loa (eye worm) hypothetical protein 0.0035 0.0036 0.0034
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0348 0.0618 0.0617
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0028 0.0027
Brugia malayi CXXC zinc finger family protein 0.0118 0.019 0.0189
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0022 0.0012 0.001
Leishmania major heat shock protein 83-1 0.0034 0.0034 0.0033
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0046 0.0057 0.0038
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.003 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.005 0.0041
Schistosoma mansoni chromobox protein 0.0076 0.0112 0.0112
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.102 0.1868 0.1867
Treponema pallidum alginate O-acetylation protein (algI) 0.0067 0.0095 1
Giardia lamblia Phosphatidylinositol 4-kinase 0.0348 0.0618 0.0608
Leishmania major glycerol uptake protein, putative 0.0067 0.0095 0.0095
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0031 0.0029 0.0028
Echinococcus granulosus cpg binding protein 0.0127 0.0206 0.0205
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0061 0.0085 0.1364
Trichomonas vaginalis PIKK family atypical protein kinase 0.4012 0.743 0.7428
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.0093 0.0092
Giardia lamblia GTOR 0.5394 1 1
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.004 0.0045 0.0044
Schistosoma mansoni hypothetical protein 0.0082 0.0124 0.0124
Echinococcus multilocularis tumor protein p63 0.0337 0.0597 0.0596
Loa Loa (eye worm) mbt repeat family protein 0.0046 0.0057 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0789 0.1437 0.1429
Onchocerca volvulus 0.0075 0.0111 0.0108
Echinococcus multilocularis neuropeptide receptor A26 0.0993 0.1817 0.1816
Loa Loa (eye worm) hypothetical protein 0.0075 0.0111 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.013 0.012
Schistosoma mansoni immunophilin 0.0061 0.0085 0.0084
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0063 0.0062
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0031 0.0029 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.3618 0.6698 0.6695
Echinococcus multilocularis mitochondrial import inner membrane translocase subunit TIM23, putative 0.004 0.0045 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0021 0.0011
Leishmania major mitochondrial DNA polymerase beta 0.0335 0.0593 0.0593
Echinococcus multilocularis jumonji domain containing protein 0.0044 0.0053 0.0052
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0081 0.0121 0.012
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0046 0.0057 0.0056
Echinococcus multilocularis sterol O acyltransferase 1 0.0686 0.1246 0.1245
Loa Loa (eye worm) hypothetical protein 0.0031 0.0029 0.0027
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0061 0.0085 0.132
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0027 0.0018
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.029 0.051 0.0509
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0029 0.0027
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0052 0.0068 0.0067
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0011 0.001
Brugia malayi heat shock protein 90 0.0034 0.0034 0.0033
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0348 0.0618 0.0818
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0061 0.0085 0.0083
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0023 0.0014 0.0013
Echinococcus granulosus methyl CpG binding domain protein 2 0.0018 0.0004 0.0002
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0348 0.0618 0.0617
Mycobacterium ulcerans aldehyde dehydrogenase 0.0129 0.0211 0.2346
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0021 0.0011
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0348 0.0618 0.0617
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0031 0.0029 0.0027
Trichomonas vaginalis CAMK family protein kinase 0.029 0.051 0.0501
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0032 0.0127
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0067 0.0095 0.0094
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0348 0.0618 0.0618
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0029 0.0027
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0057 0.0613
Echinococcus granulosus nibrin 0.003 0.0028 0.0026
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0041 0.0047 0.0047
Trypanosoma cruzi heat shock protein 85, putative 0.0034 0.0034 0.0033
Echinococcus multilocularis sterol regulatory element binding protein 0.0085 0.013 0.0128
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.003 0.0028 0.0022
Trichomonas vaginalis chromobox protein, putative 0.0046 0.0056 0.0047
Brugia malayi CHD4 protein 0.0021 0.001 0.0009
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0023 0.0014 0.0013
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0061 0.0085 0.0084
Loa Loa (eye worm) hypothetical protein 0.0075 0.0111 0.0109
Loa Loa (eye worm) hypothetical protein 0.0027 0.0021 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0021 0.0011
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0348 0.0618 0.0618
Toxoplasma gondii aldehyde dehydrogenase 0.0129 0.0211 0.027
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0067 0.0095 0.0095
Trypanosoma brucei heat shock protein 90, putative 0.0034 0.0034 0.0033
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0057 0.0056
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0067 0.0095 0.1538
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0348 0.0618 0.0609
Trichomonas vaginalis fk506-binding protein, putative 0.0061 0.0085 0.0075
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0057 0.0057
Echinococcus multilocularis expressed conserved protein 0.0187 0.0319 0.0317
Entamoeba histolytica protein kinase 2, putative 0.0023 0.0014 0.0014
Echinococcus granulosus polycomb protein SCMH1 0.0046 0.0057 0.0055
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.003 0.0028 0.0026
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0075 0.0111 0.011
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0021 0.0011
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0057 0.0057
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0111 0.011
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0041 0.0041
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0029 0.0027
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.5394 1 1
Loa Loa (eye worm) hypothetical protein 0.0073 0.0107 0.0106
Mycobacterium tuberculosis Possible penicillin-binding protein 0.048 0.0863 0.9571
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM23, putative 0.004 0.0045 0.0718
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.029 0.051 0.0509
Schistosoma mansoni DNA helicase recq5 0.0022 0.0011 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.2908 0.5378 0.5374
Echinococcus granulosus o acyltransferase membrane bound domain 0.0067 0.0095 0.0094
Brugia malayi Bromodomain containing protein 0.0038 0.0041 0.004
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0075 0.0111 0.011
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0129 0.0211 0.021
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1809 0.3334 0.3334
Echinococcus multilocularis zinc finger protein 0.0031 0.0028 0.0026
Loa Loa (eye worm) hypothetical protein 0.0031 0.0029 0.0027
Giardia lamblia Replication factor C, subunit 1 0.003 0.0028 0.0016
Mycobacterium tuberculosis Conserved protein 0.0075 0.0111 0.1019
Trypanosoma cruzi heat shock protein 90, putative 0.0034 0.0034 0.0033
Loa Loa (eye worm) hypothetical protein 0.0047 0.0057 0.0056
Echinococcus granulosus o acyltransferase membrane bound domain 0.0067 0.0095 0.0094
Loa Loa (eye worm) phosphatidylinositol 3 0.0348 0.0618 0.0617
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0136 0.0223 0.0223
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.001
Toxoplasma gondii heat shock protein 90, putative 0.0034 0.0034 0.003
Loa Loa (eye worm) phosphatidylinositol 3 0.0348 0.0618 0.0617
Mycobacterium tuberculosis Probable lipase LipE 0.0075 0.0111 0.1019
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0202 0.0347 0.0346
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0061 0.0085 0.0074
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0348 0.0618 1
Trypanosoma cruzi glycerol uptake protein, putative 0.0067 0.0095 0.0095
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0075 0.0111 0.1019
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0158 0.0266 0.0265
Schistosoma mansoni RAR-like nuclear receptor 0.0031 0.0029 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0095 0.0086
Trichomonas vaginalis PIKK family atypical protein kinase 0.5394 1 1
Trypanosoma brucei heat shock protein, putative 0.0034 0.0034 0.0033
Trypanosoma cruzi GUP1, putative 0.0067 0.0095 0.0095
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0001 0.0001
Trichomonas vaginalis CAMK family protein kinase 0.029 0.051 0.0501
Loa Loa (eye worm) hypothetical protein 0.0067 0.0095 0.0094
Brugia malayi topoisomerase 0.003 0.0028 0.0026
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0081 0.0121 0.012
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0148 0.0246 0.0245
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0039 0.003
Loa Loa (eye worm) phosphatidylinositol 3 0.0348 0.0618 0.0617
Loa Loa (eye worm) MH2 domain-containing protein 0.0115 0.0185 0.0184
Echinococcus multilocularis protein patched 0.0085 0.013 0.0128
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0056 0.0075 0.0074
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0044 0.0034
Onchocerca volvulus Protein ultraspiracle homolog 0.0031 0.0029 0.0001
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0047 0.0057 0.0638
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.003 0.0028 0.0018
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0022 0.0349
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0039 0.0044 0.0034
Leishmania major phosphatidylinositol kinase, putative 0.0348 0.0618 0.0618
Trichomonas vaginalis PIKK family atypical protein kinase 0.2908 0.5378 0.5374
Brugia malayi steroid hormone receptor 0.0031 0.0029 0.0027
Echinococcus granulosus lamin 0.0056 0.0075 0.0074
Onchocerca volvulus 0.0033 0.0033 0.0007
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0136 0.0223 0.0222
Trichomonas vaginalis PIKK family atypical protein kinase 0.2912 0.5386 0.5382
Loa Loa (eye worm) hypothetical protein 0.003 0.0028 0.0026
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0067 0.0095 0.0095
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.003 0.0028 0.0018
Trypanosoma brucei hypothetical protein, conserved 0.0075 0.0111 0.011
Trichomonas vaginalis CAMK family protein kinase 0.0144 0.0238 0.0229
Schistosoma mansoni chromosome transmission fidelity factor 0.003 0.0028 0.0027
Leishmania major hypothetical protein, conserved 0.0027 0.0022 0.0022
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0022 0.0011 0.001
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0017 0.0008
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0011 0.001
Toxoplasma gondii hypothetical protein 0.0067 0.0095 0.0114
Loa Loa (eye worm) CXXC zinc finger family protein 0.0118 0.019 0.0189
Trichomonas vaginalis PIKK family atypical protein kinase 0.102 0.1868 0.186
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0047 0.0057 0.0638
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0067 0.0095 0.0094
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0021 0.002
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.003 0.0027 0.0026
Leishmania major heat shock protein 83-1 0.0034 0.0034 0.0033
Mycobacterium tuberculosis Conserved hypothetical protein 0.0348 0.0618 0.6788
Trichomonas vaginalis PIKK family atypical protein kinase 0.1809 0.3334 0.3328
Onchocerca volvulus 0.0046 0.0057 0.0038
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0067 0.0095 0.0095
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.003 0.0028 0.0018
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0031 0.0029 0.0028
Loa Loa (eye worm) hypothetical protein 0.0031 0.0029 0.0027
Plasmodium vivax hypothetical protein, conserved 0.0348 0.0618 1
Schistosoma mansoni zinc finger protein 0.0067 0.0095 0.0095
Entamoeba histolytica serine/threonine protein kinase, putative 0.029 0.051 0.0509
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0081 0.0121 0.012
Trypanosoma brucei heat shock protein, putative 0.0034 0.0034 0.0033
Schistosoma mansoni coup transcription factor 0.0031 0.0029 0.0028
Loa Loa (eye worm) hypothetical protein 0.0238 0.0414 0.0412
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0031 0.0029 0.0027
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0032 0.0127
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0335 0.0593 0.0593
Loa Loa (eye worm) phosphatidylinositol 3 0.5394 1 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0031 0.0029 0.0027
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0031 0.0029 0.0027
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0044 0.0034
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0011 0.0009
Trypanosoma cruzi GUP1, putative 0.0067 0.0095 0.0095
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.003 0.0028 1
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0348 0.0618 0.0617
Entamoeba histolytica protein kinase rad3, putative 0.102 0.1868 0.1867
Plasmodium vivax endoplasmin, putative 0.0034 0.0034 0.0489
Echinococcus granulosus GPCR family 2 0.0081 0.0121 0.012
Trichomonas vaginalis PIKK family atypical protein kinase 0.3501 0.6482 0.6478
Echinococcus multilocularis 0.0348 0.0618 0.0617
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0061 0.0085 0.0941
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0348 0.0618 0.0617
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0348 0.0618 0.0618
Brugia malayi Bromodomain containing protein 0.0043 0.0051 0.005
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0136 0.0223 0.0223
Loa Loa (eye worm) hypothetical protein 0.0789 0.1437 0.1436
Leishmania major heat shock protein 83-1 0.0034 0.0034 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0021 0.0011
Loa Loa (eye worm) hypothetical protein 0.0067 0.0095 0.0094
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0348 0.0618 0.0618
Trichomonas vaginalis PIKK family atypical protein kinase 0.4605 0.8534 0.8532
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0067 0.0095 0.0094
Leishmania major hypothetical protein, conserved 0.0348 0.0618 0.0618
Brugia malayi beta-lactamase family protein 0.0075 0.0111 0.0109
Trichomonas vaginalis PIKK family atypical protein kinase 0.429 0.7948 0.7946
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0348 0.0618 0.0609
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0031 0.0029 0.0027
Echinococcus granulosus endoplasmin 0.0027 0.0021 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.3223 0.5964 0.596
Schistosoma mansoni hypothetical protein 0.168 0.3094 0.3094
Echinococcus granulosus sterol O acyltransferase 1 0.0686 0.1246 0.1245
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0048 0.006 0.006
Loa Loa (eye worm) hhat protein 0.0067 0.0095 0.0094
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.102 0.1868 0.1867
Trichomonas vaginalis PIKK family atypical protein kinase 0.1809 0.3334 0.3328
Echinococcus multilocularis tar DNA binding protein 0.0257 0.0448 0.0447
Brugia malayi Hhat protein 0.0067 0.0095 0.0094
Echinococcus granulosus heat shock protein 0.0034 0.0034 0.0032
Onchocerca volvulus Huntingtin homolog 0.0238 0.0414 0.0505
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0251 0.0438 0.0438
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.003 0.0028 0.0306
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0061 0.0085 0.0083
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.0001 0.0001
Onchocerca volvulus 0.0048 0.006 0.0043
Schistosoma mansoni aldehyde dehydrogenase 0.0129 0.0211 0.0211
Schistosoma mansoni myst-related protein 0.0016 0.0001 0.0000035746
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0052 0.0068 0.0067
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0031 0.0029 0.0027
Brugia malayi photoreceptor-specific nuclear receptor 0.0031 0.0029 0.0027
Schistosoma mansoni serine/threonine-protein kinase 0.0025 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0686 0.1246 0.1245
Schistosoma mansoni intermediate filament proteins 0.0056 0.0075 0.0075
Mycobacterium tuberculosis Probable lipase LipD 0.0075 0.0111 0.1019
Trypanosoma cruzi heat shock protein 90, putative 0.002 0.0008 0.0007
Schistosoma mansoni immunophilin 0.0061 0.0085 0.0084
Brugia malayi Pre-SET motif family protein 0.0036 0.0037 0.0036
Schistosoma mansoni cpg binding protein 0.0127 0.0206 0.0206
Loa Loa (eye worm) phosphatidylinositol 3 0.0348 0.0618 0.0617
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0011 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.1137 0.2084 0.2077
Trichomonas vaginalis PIKK family atypical protein kinase 0.429 0.7948 0.7946
Loa Loa (eye worm) hypothetical protein 0.004 0.0045 0.0044
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0018 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0035 0.0036 0.0034
Mycobacterium ulcerans lipase LipD 0.0075 0.0111 0.1228
Trypanosoma cruzi Protein kinase B 0.0025 0.0018 0.0018
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0022 0.0022
Brugia malayi mbt repeat family protein 0.0046 0.0057 0.0056
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0023 0.0014 0.0169
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0053 0.007 0.007
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0072 0.0105 0.0104
Entamoeba histolytica hypothetical protein 0.0038 0.0041 0.0041
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0061 0.0085 0.0084
Schistosoma mansoni fkbp-rapamycin associated protein 0.102 0.1868 0.1867
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0021 0.0011
Brugia malayi Calcitonin receptor-like protein seb-1 0.0255 0.0445 0.0444
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0061 0.0085 0.0075
Schistosoma mansoni heat shock protein 0.0034 0.0034 0.0033
Echinococcus granulosus bloom syndrome protein 0.0022 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0348 0.0618 0.0617
Trichomonas vaginalis PIKK family atypical protein kinase 0.4012 0.743 0.7428
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0031 0.0029 0.0027
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0348 0.0618 1
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0047 0.0057 0.0416
Brugia malayi MBOAT family protein 0.0067 0.0095 0.0094
Loa Loa (eye worm) hypothetical protein 0.0081 0.0121 0.012
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0095 0.0086
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0348 0.0618 0.0618
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0067 0.0095 0.0095
Onchocerca volvulus 0.0031 0.0029 0.0001
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0061 0.0085 0.0084
Trichomonas vaginalis set domain proteins, putative 0.0265 0.0464 0.0455
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0348 0.0618 0.0609
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0035 0.0036 0.0395
Trichomonas vaginalis PIKK family atypical protein kinase 0.4012 0.743 0.7428
Echinococcus granulosus PHD finger protein rhinoceros 0.0032 0.003 0.0029
Mycobacterium tuberculosis Conserved protein 0.0075 0.0111 0.1019
Mycobacterium leprae conserved hypothetical protein 0.0348 0.0618 1
Loa Loa (eye worm) histone methyltransferase 0.0038 0.0041 0.004
Echinococcus multilocularis chromobox protein 1 0.0076 0.0112 0.0111
Brugia malayi PHD-finger family protein 0.0019 0.0006 0.0005
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0348 0.0618 0.0609
Trichomonas vaginalis CAMK family protein kinase 0.029 0.051 0.0501
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0348 0.0618 0.0608
Onchocerca volvulus Serine\/threonine kinase homolog 0.029 0.051 0.063
Loa Loa (eye worm) jmjC domain-containing protein 0.0047 0.0059 0.0057
Leishmania major glycerol uptake protein, putative 0.0067 0.0095 0.0095
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0348 0.0618 0.0618
Echinococcus multilocularis microtubule associated protein 2 0.2112 0.3898 0.3897
Loa Loa (eye worm) hypothetical protein 0.0052 0.0068 0.0067
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0348 0.0618 0.0609
Entamoeba histolytica hypothetical protein 0.0038 0.0041 0.0041
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0037 0.0037
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.224 0.4137 0.4136
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0348 0.0618 0.0618
Loa Loa (eye worm) hypothetical protein 0.0026 0.0019 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.429 0.7948 0.7946
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0057 0.0056
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0067 0.0095 0.0095
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0348 0.0618 0.0617
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0044 0.0034
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0348 0.0618 0.0618
Giardia lamblia Hypothetical protein 0.0348 0.0618 0.0608
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0061 0.0085 0.0083
Echinococcus granulosus fetal alzheimer antigen falz 0.003 0.0027 0.0026
Echinococcus granulosus geminin 0.1024 0.1874 0.1873
Trypanosoma cruzi target of rapamycin kinase 3 0.4295 0.7956 0.7956
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0022 0.0011 0.0172
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0348 0.0618 0.0618
Entamoeba histolytica hypothetical protein 0.0348 0.0618 0.0618
Schistosoma mansoni lamin 0.0056 0.0075 0.0075
Echinococcus multilocularis Glutaredoxin protein 5 0.0022 0.0012 0.001
Schistosoma mansoni serine/threonine protein kinase 0.029 0.051 0.0509
Echinococcus granulosus nervana 2 0.0022 0.0012 0.001
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0032 0.0127
Trichomonas vaginalis PIKK family atypical protein kinase 0.2908 0.5378 0.5374
Mycobacterium ulcerans esterase/lipase LipP 0.0075 0.0111 0.1228
Schistosoma mansoni hypothetical protein 0.1024 0.1874 0.1874
Trypanosoma cruzi heat shock protein 85, putative 0.0034 0.0034 0.0033
Entamoeba histolytica hypothetical protein 0.0348 0.0618 0.0618
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0348 0.0618 0.0618
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0057 0.0078 0.0077
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0348 0.0618 0.0818
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0031 0.0028 0.0026
Brugia malayi p70 ribosomal S6 kinase beta 0.0034 0.0035 0.0034
Trichomonas vaginalis PIKK family atypical protein kinase 0.4012 0.743 0.7428
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0067 0.0095 0.0114
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0081 0.0121 0.012
Onchocerca volvulus Bile acid receptor homolog 0.0031 0.0029 0.0001
Echinococcus multilocularis histone acetyltransferase MYST2 0.0052 0.0068 0.0067
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.5394 1 1
Onchocerca volvulus Alhambra homolog 0.0032 0.003 0.0003
Brugia malayi jmjC domain containing protein 0.0104 0.0165 0.0163
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0027 0.0018
Brugia malayi serine/threonine-protein kinase plk-2 0.029 0.051 0.0509
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0018 0.0004 0.0051
Brugia malayi hydrolase, alpha/beta fold family protein 0.2065 0.3811 0.381
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0348 0.0618 0.0617
Schistosoma mansoni tar DNA-binding protein 0.0257 0.0448 0.0448
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0255 0.0445 0.0444
Loa Loa (eye worm) heterochromatin protein 1 0.0076 0.0112 0.0111
Plasmodium falciparum phd finger protein, putative 0.0032 0.003 0.0479
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.1809 0.3334 0.3334
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0022 0.0011 0.001
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0136 0.0223 0.0222
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0348 0.0618 0.0618
Schistosoma mansoni myst-related protein 0.0016 0.0001 0.0000035746
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0005 0.0004
Brugia malayi MBOAT family protein 0.0067 0.0095 0.0094
Entamoeba histolytica hypothetical protein 0.0038 0.0041 0.0041
Toxoplasma gondii ABC1 family protein 0.0075 0.0111 0.0134
Schistosoma mansoni aldehyde dehydrogenase 0.0129 0.0211 0.0211
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0047 0.0057 0.0416
Trichomonas vaginalis immunophilin, putative 0.0061 0.0085 0.0075
Brugia malayi Steroid receptor seven-up type 2 0.0031 0.0029 0.0027
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0255 0.0445 0.0444
Echinococcus multilocularis neuropeptide s receptor 0.0993 0.1817 0.1816
Brugia malayi MBOAT family protein 0.0067 0.0095 0.0094
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0348 0.0618 0.0609
Schistosoma mansoni serine/threonine-protein kinase 0.0025 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0075 0.0111 0.0109
Echinococcus multilocularis rac serine:threonine kinase 0.0025 0.0018 0.0017
Entamoeba histolytica protein kinase, putative 0.0034 0.0035 0.0034
Plasmodium vivax hypothetical protein, conserved 0.0032 0.003 0.043
Echinococcus granulosus chromobox protein 1 0.0076 0.0112 0.0111
Loa Loa (eye worm) steroid hormone receptor 0.0031 0.0029 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.102 0.1868 0.186
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0255 0.0445 0.0444
Echinococcus granulosus mixed lineage leukemia protein mll 0.0031 0.0028 0.0026
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0027 0.0026
Brugia malayi PHD-finger family protein 0.0036 0.0038 0.0037
Loa Loa (eye worm) hypothetical protein 0.1099 0.2015 0.2014
Onchocerca volvulus 0.0075 0.0111 0.0108
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.1809 0.3334 0.3333
Loa Loa (eye worm) bromodomain containing protein 0.0022 0.0012 0.001
Onchocerca volvulus Huntingtin homolog 0.0238 0.0414 0.0505
Mycobacterium ulcerans epoxide hydrolase EphA 0.05 0.0901 1
Brugia malayi MH2 domain containing protein 0.0115 0.0185 0.0184
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0031 0.0029 0.0027
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0348 0.0618 0.0818
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0136 0.0223 0.0222
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.5394 1 1
Brugia malayi nuclear receptor NHR-88 0.0031 0.0029 0.0027
Echinococcus multilocularis lamin 0.0056 0.0075 0.0074
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0075 0.0111 0.0109
Brugia malayi mbt repeat family protein 0.0046 0.0057 0.0056
Trypanosoma brucei target of rapamycin kinase 3, putative 0.4295 0.7956 0.7956
Brugia malayi Bromodomain containing protein 0.0088 0.0135 0.0134
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0075 0.0111 0.1019
Loa Loa (eye worm) hypothetical protein 0.003 0.0028 0.0026
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0067 0.0095 0.0094
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0348 0.0618 0.0618
Trichomonas vaginalis PIKK family atypical protein kinase 0.5394 1 1
Loa Loa (eye worm) acetyltransferase 0.0148 0.0246 0.0244
Schistosoma mansoni kinase 0.0147 0.0245 0.0245
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0039 0.003
Plasmodium falciparum endoplasmin, putative 0.0021 0.0009 0.0144
Entamoeba histolytica hypothetical protein 0.0067 0.0095 0.0095
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0348 0.0618 1
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0029 0.0028
Toxoplasma gondii mitochondrial inner membrane translocase subunit TIM17, putative 0.004 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0075 0.0111 0.0109
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0022 0.0011 0.000000000024674
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0104 0.0165 0.0163
Toxoplasma gondii ATPase, AAA family protein 0.003 0.0028 0.0022
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0348 0.0618 0.0617
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0023 0.0014 0.0014
Brugia malayi MBOAT family protein 0.0067 0.0095 0.0094
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0031 0.0029 0.0027
Trichomonas vaginalis CAMK family protein kinase 0.029 0.051 0.0501
Loa Loa (eye worm) hypothetical protein 0.1137 0.2084 0.2083
Echinococcus multilocularis lysine specific demethylase 5A 0.0038 0.0043 0.0041
Schistosoma mansoni heat shock protein 0.0034 0.0034 0.0033
Brugia malayi RNA recognition motif domain containing protein 0.0257 0.0448 0.0447
Echinococcus granulosus nervana 2 0.0022 0.0012 0.001
Trichomonas vaginalis chromobox protein, putative 0.0076 0.0112 0.0103
Entamoeba histolytica hypothetical protein 0.102 0.1868 0.1867
Schistosoma mansoni hypothetical protein 0.0032 0.003 0.003
Schistosoma mansoni hypothetical protein 0.004 0.0045 0.0044
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0011 0.0011
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.005 0.0029
Onchocerca volvulus 0.0348 0.0618 0.0771
Echinococcus multilocularis polycomb protein SCMH1 0.0046 0.0057 0.0055
Trypanosoma brucei heat shock protein, putative 0.0034 0.0034 0.0033
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0011 0.0002
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0067 0.0095 0.0095
Echinococcus granulosus replication factor c subunit 1 0.003 0.0028 0.0026
Loa Loa (eye worm) hypothetical protein 0.003 0.0028 0.0026
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0348 0.0618 0.0609
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0348 0.0618 1
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0067 0.0095 0.0094
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.005 0.0041
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0789 0.1437 0.1436
Entamoeba histolytica hypothetical protein 0.003 0.0028 0.0027
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0055 0.0054
Brugia malayi hypothetical protein 0.003 0.0028 0.0026
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0199 0.0341 0.034
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0031 0.0029 0.0028
Brugia malayi hypothetical protein 0.0036 0.0038 0.0037
Schistosoma mansoni bromodomain containing protein 0.0076 0.0112 0.0112
Echinococcus multilocularis serine protein kinase ATM 0.102 0.1868 0.1867
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0031 0.0029 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.2912 0.5386 0.5382
Trichomonas vaginalis PIKK family atypical protein kinase 0.0348 0.0618 0.0609
Loa Loa (eye worm) FKBP5 protein 0.0061 0.0085 0.0083
Leishmania major heat shock protein 83-1 0.0034 0.0034 0.0033
Brugia malayi beta-lactamase 0.0075 0.0111 0.0109
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0057 0.0056
Onchocerca volvulus 0.0047 0.0057 0.0039
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0021 0.002
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.1809 0.3334 0.3334
Schistosoma mansoni topbp1 0.003 0.0028 0.0027
Schistosoma mansoni hypothetical protein 0.0038 0.0041 0.0041
Schistosoma mansoni cpg binding protein 0.0118 0.019 0.019
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.0035 0.0036 0.0034
Brugia malayi jmjC domain containing protein 0.0047 0.0059 0.0058
Giardia lamblia Kinase, AGC PKA 0.0023 0.0014 0.0003
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0348 0.0618 0.0609
Brugia malayi Pre-SET motif family protein 0.0233 0.0405 0.0404
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.102 0.1868 0.1867
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0031 0.0028 0.0026
Loa Loa (eye worm) hypothetical protein 0.003 0.0028 0.0026
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0129 0.0211 0.0211
Trichomonas vaginalis PIKK family atypical protein kinase 0.3223 0.5964 0.596
Mycobacterium leprae Probable lipase LipE 0.0075 0.0111 0.1501
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0061 0.0085 0.0084
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0031 0.0029 0.0028
Echinococcus multilocularis chromobox protein 1 0.0076 0.0112 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0021 0.0011
Echinococcus granulosus lysine specific demethylase 5A 0.0047 0.0059 0.0057
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0034 0.0035 0.0033
Echinococcus granulosus Protein patched homolog 1 0.0085 0.013 0.0128
Entamoeba histolytica hypothetical protein, conserved 0.0067 0.0095 0.0095
Trypanosoma brucei glycerol uptake protein, putative 0.0067 0.0095 0.0095
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0039 0.003
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0035 0.0036 0.0167
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.003 0.0028 0.0112
Loa Loa (eye worm) phosphatidylinositol 3 0.1809 0.3334 0.3333
Plasmodium vivax hypothetical protein, conserved 0.0075 0.0111 0.174
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0031 0.0029 0.0027
Schistosoma mansoni hypothetical protein 0.0082 0.0124 0.0124
Trypanosoma cruzi FHA domain containing protein, putative 0.003 0.0028 0.0027
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0348 0.0618 0.0617
Schistosoma mansoni jumonji/arid domain-containing protein 0.0047 0.0059 0.0058
Leishmania major hypothetical protein, conserved 0.0067 0.0095 0.0095
Mycobacterium ulcerans aldehyde dehydrogenase 0.0129 0.0211 0.2346
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0348 0.0618 0.0617
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0233 0.0405 0.0403
Loa Loa (eye worm) RNA binding protein 0.0257 0.0448 0.0447
Echinococcus granulosus serine:threonine protein kinase PLK1 0.029 0.051 0.0509
Echinococcus multilocularis heat shock protein 90 0.0027 0.0021 0.002
Schistosoma mansoni myelin transcription factor 1 myt1 0.0052 0.0068 0.0068
Leishmania major heat shock protein 83-1 0.0034 0.0034 0.0033
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0022 0.0011 0.001
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0029 0.0028
Loa Loa (eye worm) phosphatidylinositol 3 0.0348 0.0618 0.0617
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0021 0.0011
Entamoeba histolytica hypothetical protein 0.0348 0.0618 0.0618
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0136 0.0223 0.0223
Schistosoma mansoni jumonji domain containing protein 0.0083 0.0125 0.0124
Echinococcus granulosus sterol regulatory element binding protein 0.0085 0.013 0.0128
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0061 0.0085 0.0084
Schistosoma mansoni lamin 0.0056 0.0075 0.0075
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0044 0.0033
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0348 0.0618 0.0618
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0348 0.0618 0.0618
Leishmania major glycerol uptake protein, putative 0.0067 0.0095 0.0095
Brugia malayi CHE-14 protein 0.0085 0.013 0.0129
Schistosoma mansoni retinoic acid receptor RXR 0.0031 0.0029 0.0028
Brugia malayi hypothetical protein 0.0018 0.0004 0.0003
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0057 0.0057
Loa Loa (eye worm) MBOAT family protein 0.0067 0.0095 0.0094
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0061 0.0085 0.0075
Loa Loa (eye worm) hypothetical protein 0.0031 0.0029 0.0027
Loa Loa (eye worm) latrophilin receptor protein 2 0.0081 0.0121 0.012
Loa Loa (eye worm) hypothetical protein 0.0026 0.0019 0.0018
Echinococcus multilocularis fk506 binding protein 0.0061 0.0085 0.0083
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0067 0.0095 0.0094
Brugia malayi Niemann-Pick C1 protein precursor 0.0199 0.0341 0.034
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0348 0.0618 0.0618
Brugia malayi Endoplasmin precursor 0.0034 0.0034 0.0033
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0022 0.0011 0.001
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.003 0.0028 0.0027
Entamoeba histolytica protein kinase, putative 0.0037 0.0039 0.0038
Echinococcus multilocularis heat shock protein 0.0034 0.0034 0.0032
Trypanosoma brucei rac serine-threonine kinase, putative 0.0037 0.0039 0.0038
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0006 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0021 0.0011
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.5394 1 1
Entamoeba histolytica vacuolar protein sorting 26 0.0067 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.003 0.0028 0.0026
Echinococcus granulosus jumonji domain containing protein 0.0044 0.0053 0.0052
Leishmania major peptidylprolyl isomerase-like protein 0.0061 0.0085 0.0084
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0044 0.0701
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0182 0.0309 0.0307
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.5394 1 1
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0348 0.0618 0.0609
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0075 0.0111 0.1228
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0182 0.0309 0.0307
Leishmania major heat shock protein 83-1 0.0034 0.0034 0.0033
Treponema pallidum DNA ligase (lig) 0.003 0.0028 0.0899
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0021 0.0011
Loa Loa (eye worm) TAR-binding protein 0.0257 0.0448 0.0447
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0075 0.0111 0.0109
Loa Loa (eye worm) hypothetical protein 0.003 0.0028 0.0026
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0335 0.0593 0.0593
Trypanosoma cruzi Heat shock protein 83, putative 0.0034 0.0034 0.0033
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0055 0.0059
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0789 0.1437 0.1436
Trichomonas vaginalis replication factor C large subunit, putative 0.003 0.0028 0.0018
Loa Loa (eye worm) hypothetical protein 0.0053 0.007 0.0069
Loa Loa (eye worm) intermediate filament protein 0.0056 0.0075 0.0074
Trichomonas vaginalis PIKK family atypical protein kinase 0.429 0.7948 0.7946
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0348 0.0618 0.0617
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0031 0.0029 0.0027
Loa Loa (eye worm) hypothetical protein 0.0031 0.0029 0.0027
Echinococcus multilocularis Niemann Pick C1 protein 0.0284 0.05 0.0498
Mycobacterium ulcerans hypothetical protein 0.0176 0.0299 0.3319
Mycobacterium ulcerans beta-lactamase 0.0075 0.0111 0.1228
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0067 0.0095 0.0094
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.0029 0.0028
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0029 0.0027
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0672 0.1221 0.122
Trichomonas vaginalis PIKK family atypical protein kinase 0.429 0.7948 0.7946
Mycobacterium leprae conserved hypothetical protein 0.0075 0.0111 0.1501
Plasmodium falciparum replication factor C subunit 1, putative 0.003 0.0028 0.0439
Loa Loa (eye worm) hypothetical protein 0.0031 0.0029 0.0027
Trypanosoma cruzi glycerol uptake protein, putative 0.0067 0.0095 0.0095
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0067 0.0095 0.0094
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0348 0.0618 0.0618
Brugia malayi PHD-finger family protein 0.0032 0.003 0.0029
Trypanosoma cruzi heat shock protein 85, putative 0.0027 0.0021 0.002
Brugia malayi Pax transcription activation domain interacting protein 0.003 0.0028 0.0026
Brugia malayi hypothetical protein 0.0238 0.0414 0.0413
Leishmania major phosphatidylinositol 3-kinase, putative 0.1809 0.3334 0.3334
Echinococcus multilocularis FTZ F1 alpha 0.0031 0.0029 0.0027
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.5394 1 1
Giardia lamblia Grp94/Hsp90 0.0027 0.0021 0.001
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0025 0.0018 0.0018
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.0061 0.0085 0.8561
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0011 0.0011
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0348 0.0618 0.0617
Trypanosoma brucei polo-like protein kinase 0.029 0.051 0.0509
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0348 0.0618 0.0609
Trichomonas vaginalis chromobox protein, putative 0.0076 0.0112 0.0103
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0348 0.0618 0.0618
Echinococcus granulosus ecdysone induced protein 78C 0.0031 0.0029 0.0027
Echinococcus granulosus o acyltransferase membrane bound domain 0.0067 0.0095 0.0094
Trichomonas vaginalis CAMK family protein kinase 0.029 0.051 0.0501
Toxoplasma gondii heat shock protein HSP90 0.0034 0.0034 0.003
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0067 0.0095 0.0114
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0031 0.0029 0.0027
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0038 0.0041 0.004
Mycobacterium tuberculosis Probable hydrolase 0.0075 0.0111 0.1019
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0348 0.0618 0.0618
Trichomonas vaginalis heat shock protein, putative 0.0027 0.0021 0.0011
Trypanosoma brucei heat shock protein, putative 0.0034 0.0034 0.0033
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0057 0.0057
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0027 0.0021 0.002
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0081 0.0121 0.012
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0348 0.0618 0.0618
Loa Loa (eye worm) MBCTL1 0.0052 0.0068 0.0067
Trichomonas vaginalis PIKK family atypical protein kinase 0.5394 1 1
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0031 0.0029 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.102 0.1868 0.186
Brugia malayi intermediate filament protein 0.0056 0.0075 0.0074
Plasmodium falciparum acyl-CoA synthetase 0.0035 0.0036 0.0568
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0348 0.0618 0.0608
Echinococcus multilocularis protein dispatched 1 0.0097 0.0152 0.0151
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0047 0.0057 0.0638
Loa Loa (eye worm) hypothetical protein 0.0047 0.0057 0.0056
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.003 0.0028 0.0027
Mycobacterium ulcerans aldehyde dehydrogenase 0.0129 0.0211 0.2346
Loa Loa (eye worm) hypothetical protein 0.0085 0.013 0.0128
Leishmania major hypothetical protein, conserved 0.0075 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.0238 0.0414 0.0412
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.5394 1 1
Trichomonas vaginalis heat shock protein, putative 0.0034 0.0034 0.0024
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0036 0.0037 0.0036
Trypanosoma brucei glycerol uptake protein, putative 0.0067 0.0095 0.0095
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0055 0.0046
Leishmania major heat shock protein 83-1 0.0034 0.0034 0.0033
Trypanosoma cruzi glycerol uptake protein, putative 0.0067 0.0095 0.0095
Leishmania major glycerol uptake protein, putative 0.0067 0.0095 0.0095
Leishmania major glycerol uptake protein, putative 0.0067 0.0095 0.0095
Leishmania major heat shock protein 83-1 0.0034 0.0034 0.0033
Echinococcus granulosus Niemann Pick C1 protein 0.0284 0.05 0.0498
Schistosoma mansoni hypothetical protein 0.028 0.0492 0.0491
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0348 0.0618 0.0618
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0029 0.0027
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0022 0.0012 0.001
Loa Loa (eye worm) hypothetical protein 0.0031 0.0029 0.0027
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0067 0.0095 0.0094
Toxoplasma gondii target of rapamycin (TOR), putative 0.4012 0.743 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0075 0.0111 0.0101
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0046 0.0056 0.0037
Trypanosoma brucei heat shock protein 90, putative 0.0034 0.0034 0.0033
Brugia malayi MBOAT family protein 0.0067 0.0095 0.0094
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0041 0.004
Loa Loa (eye worm) hypothetical protein 0.004 0.0045 0.0043
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0061 0.0085 0.0084
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.4002 0.7411 0.7411
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0022 0.0022
Trypanosoma cruzi polo-like protein kinase, putative 0.029 0.051 0.0509
Echinococcus multilocularis ecdysone induced protein 78C 0.0031 0.0029 0.0027
Loa Loa (eye worm) hypothetical protein 0.0031 0.0029 0.0027
Trypanosoma brucei heat shock protein, putative 0.0034 0.0034 0.0033
Toxoplasma gondii AGC kinase 0.0034 0.0035 0.0032
Echinococcus multilocularis dnaJ subfamily B 0.168 0.3094 0.3093
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0061 0.0085 0.0083
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.1809 0.3334 0.3334
Brugia malayi beta-lactamase family protein 0.0075 0.0111 0.0109
Loa Loa (eye worm) RecQ helicase 0.0022 0.0011 0.001
Onchocerca volvulus 0.0067 0.0095 0.0089
Brugia malayi Heterochromatin protein 1 0.0076 0.0112 0.0111
Echinococcus granulosus histone acetyltransferase KAT2B 0.0141 0.0234 0.0232
Trichomonas vaginalis PIKK family atypical protein kinase 0.0348 0.0618 0.0609
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.05 0.0901 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0044 0.0034
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0335 0.0593 0.0593
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0039 0.0044 0.0034
Schistosoma mansoni tar DNA-binding protein 0.0257 0.0448 0.0448
Echinococcus multilocularis Niemann Pick C1 protein 0.0199 0.0341 0.034
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.003 0.0028 0.0018
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0348 0.0618 0.0617
Loa Loa (eye worm) hypothetical protein 0.0032 0.003 0.0029
Giardia lamblia PHD finger protein 15 0.0032 0.003 0.0019
Schistosoma mansoni hypothetical protein 0.1024 0.1874 0.1874
Echinococcus granulosus microtubule associated protein 2 0.2112 0.3898 0.3897
Toxoplasma gondii non-specific serine/threonine protein kinase 0.1137 0.2084 0.2795
Schistosoma mansoni immunophilin 0.0053 0.0069 0.0069
Brugia malayi Latrophilin receptor protein 2 0.0081 0.0121 0.012
Echinococcus granulosus histone lysine methyltransferase setb 0.0053 0.007 0.0069
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.5394 1 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0022 0.0349
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0348 0.0618 0.0609
Loa Loa (eye worm) hypothetical protein 0.0174 0.0295 0.0294
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0027 0.0021 0.002
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.003 0.0026
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0129 0.0211 0.021
Echinococcus granulosus neuropeptide receptor A26 0.0993 0.1817 0.1816
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.102 0.1868 0.1867
Loa Loa (eye worm) beta-lactamase 0.0075 0.0111 0.0109
Entamoeba histolytica hypothetical protein 0.0038 0.0041 0.0041
Trichomonas vaginalis CAMK family protein kinase 0.029 0.051 0.0501
Schistosoma mansoni hypothetical protein 0.0081 0.0121 0.012
Echinococcus multilocularis cpg binding protein 0.0127 0.0206 0.0205
Giardia lamblia Heat shock protein HSP 90-alpha 0.0034 0.0034 0.0023
Schistosoma mansoni sterol O-acyltransferase 1 0.0686 0.1246 0.1245
Schistosoma mansoni DNA helicase recq1 0.0022 0.0011 0.0011
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.0061 0.0085 0.0074
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0348 0.0618 0.0618
Trichomonas vaginalis PIKK family atypical protein kinase 0.3223 0.5964 0.596
Plasmodium falciparum heat shock protein 90 0.0034 0.0034 0.0537
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0028 0.0018
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0067 0.0095 0.0094
Schistosoma mansoni hypothetical protein 0.0348 0.0618 0.0618
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0039 0.003
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0348 0.0618 0.0818
Schistosoma mansoni steroid hormone receptor ad4bp 0.0031 0.0029 0.0028
Echinococcus granulosus Glutaredoxin protein 5 0.0022 0.0012 0.001
Schistosoma mansoni patched 1 0.0085 0.013 0.0129
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.004 0.0039
Echinococcus multilocularis Zinc finger, PHD finger 0.0348 0.0618 0.0617
Schistosoma mansoni jumonji/arid domain-containing protein 0.0047 0.0059 0.0058
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0067 0.0095 0.0094
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0061 0.0085 0.0084
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0348 0.0618 0.0617
Schistosoma mansoni hypothetical protein 0.0081 0.0121 0.012
Echinococcus multilocularis fetal alzheimer antigen, falz 0.003 0.0027 0.0026
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.003 0.0028 0.0027
Trypanosoma brucei heat shock protein, putative 0.0034 0.0034 0.0033
Trypanosoma cruzi heat shock protein 90, putative 0.0027 0.0021 0.002
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0027 0.0025
Loa Loa (eye worm) hydrolase 0.4133 0.7655 0.7655
Loa Loa (eye worm) hypothetical protein 0.102 0.1868 0.1867
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.004 0.0045 0.0044
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.004 0.0039
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0031 0.0029 0.0027
Giardia lamblia Kinase, PLK 0.029 0.051 0.0499
Loa Loa (eye worm) phosphatidylinositol kinase 0.0348 0.0618 0.0617
Loa Loa (eye worm) hypothetical protein 0.0199 0.0341 0.034
Schistosoma mansoni hypothetical protein 0.0082 0.0124 0.0124
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0028 0.0018
Loa Loa (eye worm) AGC/AKT protein kinase 0.0037 0.0039 0.0038
Echinococcus granulosus dnaJ subfamily B 0.168 0.3094 0.3093
Schistosoma mansoni chromobox protein 0.0076 0.0112 0.0112
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0136 0.0223 0.0222
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM23, putative 0.004 0.0045 0.067

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) > 260 uM PUBCHEM_BIOASSAY: Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493224] ChEMBL. No reference
Potency (functional) 2.2387 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 9.285 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 20.5878 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 20.5962 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 31.6228 uM PubChem BioAssay. qHTS Assay for Activators of ClpP. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) 56.2341 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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