Detailed information for compound 1036527

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 241.626 | Formula: C7H12ClNO6
  • H donors: 3 H acceptors: 5 LogP: -3.42 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)C(CC(=O)O)(CC(=O)O)N.Cl
  • InChi: 1S/C7H11NO6.ClH/c1-14-6(13)7(8,2-4(9)10)3-5(11)12;/h2-3,8H2,1H3,(H,9,10)(H,11,12);1H
  • InChiKey: SQNZWVALOOOEKW-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.004 0.0049 0.0165
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0019 0.0004 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0004 0.0004
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0046 0.0142
Schistosoma mansoni septate junction protein 0.0019 0.0004 0.0004
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0035 0.005
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0046 0.0145
Echinococcus granulosus tyrosine protein kinase csk 0.0019 0.0004 0.0005
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.003 0.0027 0.0038
Echinococcus multilocularis 0.0205 0.041 0.0586
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0024 0.0014 0.0048
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0065 0.0094
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0019 0.0004 0.0005
Echinococcus granulosus mixed lineage leukemia protein mll 0.003 0.0027 0.0038
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0019 0.0004 0.0015
Brugia malayi Protein kinase domain containing protein 0.0019 0.0004 0.0012
Brugia malayi glutathione reductase 0.0047 0.0065 0.0219
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0205 0.041 0.5722
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0158 0.0306 0.1023
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0114 0.0211 0.0211
Echinococcus granulosus roundabout 2 0.023 0.0466 0.0665
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0019 0.0004 0.0006
Echinococcus multilocularis lachesin 0.004 0.0049 0.0071
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0205 0.041 0.5722
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0108 0.0198 0.1231
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.004 0.005 0.0167
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0021 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0012
Echinococcus multilocularis Peptidase C54 0.0059 0.0091 0.0129
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0388 0.0809 0.0809
Trichomonas vaginalis DNA polymerase eta, putative 0.0038 0.0046 0.0142
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0022
Loa Loa (eye worm) TK/ALK protein kinase 0.0019 0.0004 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.001 0.002
Brugia malayi latrophilin 2 splice variant baaae 0.0212 0.0426 0.1424
Echinococcus multilocularis tyrosine kinase 0.0019 0.0004 0.0005
Brugia malayi Immunoglobulin I-set domain containing protein 0.0021 0.0007 0.0022
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0008 0.0013
Echinococcus multilocularis tyrosine protein kinase Srms 0.0019 0.0004 0.0005
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.005 0.0156
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0114 0.0211 0.1317
Echinococcus multilocularis musashi 0.0026 0.0019 0.0028
Schistosoma mansoni peptidase 0.0019 0.0004 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0021 0.0059
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0019 0.0004 0.0006
Schistosoma mansoni serine/threonine protein kinase 0.0034 0.0036 0.0036
Brugia malayi serine/threonine-protein kinase plk-2 0.1387 0.2994 1
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0044 0.0057 0.0082
Toxoplasma gondii ABC1 family protein 0.0114 0.0211 0.1849
Echinococcus multilocularis protein kinase 0.0019 0.0004 0.0005
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0019 0.0004 0.0005
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0043 0.0131
Brugia malayi Phospholipase A2 family protein 0.0092 0.0163 0.0543
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0019 0.0004 0.0031
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0065 0.0219
Brugia malayi Protein kinase domain containing protein 0.0019 0.0004 0.0012
Schistosoma mansoni tyrosine kinase 0.0019 0.0004 0.0004
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0025 0.0036
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0098 0.0177 0.0253
Brugia malayi MH1 domain containing protein 0.0019 0.0003 0.0009
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0114 0.0211 0.0706
Trypanosoma cruzi cytochrome P450, putative 0.0342 0.0711 0.2364
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0008 0.0042
Schistosoma mansoni smad1 5 8 and 0.0034 0.0036 0.0036
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0046 0.0145
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0205 0.041 0.5722
Entamoeba histolytica protein kinase , putative 0.054 0.1143 0.3811
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0033 0.0035 0.005
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0205 0.041 0.2598
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.3218 0.6996 1
Brugia malayi Thioredoxin reductase 0.0047 0.0065 0.0219
Loa Loa (eye worm) CYP4Cod1 0.0342 0.0711 0.2373
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0043 1
Loa Loa (eye worm) glutaminase 2 0.0302 0.0622 0.2077
Schistosoma mansoni protein kinase 0.0019 0.0004 0.0004
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0008 0.0013
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0012
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0205 0.041 0.5722
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0043 0.0131
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0013 0.0032
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0043 0.0131
Loa Loa (eye worm) TK/INSR protein kinase 0.0019 0.0004 0.0012
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0023 0.0011 0.0016
Schistosoma mansoni hypothetical protein 0.0019 0.0004 0.0004
Schistosoma mansoni tyrosine kinase 0.0019 0.0004 0.0004
Schistosoma mansoni cell adhesion molecule 0.0019 0.0004 0.0004
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.004 0.005 0.0072
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0012
Echinococcus granulosus peroxidasin 0.004 0.005 0.0071
Plasmodium falciparum acyl-CoA synthetase 0.0039 0.0048 0.0421
Toxoplasma gondii hypothetical protein 0.0022 0.001 0.0084
Schistosoma mansoni titin 0.0024 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0053 0.0077 0.0258
Trichomonas vaginalis CAMK family protein kinase 0.1387 0.2994 1
Schistosoma mansoni titin 0.004 0.0049 0.0049
Echinococcus granulosus Immunoglobulin 0.0019 0.0004 0.0006
Echinococcus granulosus Peptidase C54 0.0059 0.0091 0.0129
Mycobacterium ulcerans aldehyde dehydrogenase 0.0183 0.0363 0.5056
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0038 0.0046 0.0066
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0205 0.041 0.5722
Loa Loa (eye worm) RGC/RGC protein kinase 0.0019 0.0004 0.0012
Brugia malayi Immunoglobulin I-set domain containing protein 0.0024 0.0014 0.0048
Brugia malayi F/Y-rich N-terminus family protein 0.0037 0.0042 0.014
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0021 0.0059
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0019 0.0004 0.0012
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0004 0.0004
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0388 0.0809 0.2702
Brugia malayi hypothetical protein 0.0019 0.0004 0.0012
Brugia malayi Immunoglobulin I-set domain containing protein 0.0024 0.0014 0.0048
Schistosoma mansoni cell adhesion molecule 0.0024 0.0014 0.0014
Echinococcus multilocularis peroxidasin 0.004 0.005 0.0071
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0019 0.0004 0.0005
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0114 0.0211 0.0211
Plasmodium vivax hypothetical protein, conserved 0.0022 0.001 0.0053
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0019 0.0004 0.0006
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0059 0.0091 0.0302
Echinococcus multilocularis tyrosine protein kinase csk 0.0019 0.0004 0.0005
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0008 0.0025
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0022
Echinococcus multilocularis neuropeptide s receptor 0.151 0.3264 0.4665
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0205 0.041 0.5722
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0108 0.0198 0.1231
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0044 0.0057 0.0057
Brugia malayi ephrin receptor 1 precursor 0.0019 0.0004 0.0012
Schistosoma mansoni autophagin-1 (C54 family) 0.0059 0.0091 0.0091
Schistosoma mansoni protein kinase 0.0019 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0015
Brugia malayi glutaminase DH11.1 0.0302 0.0622 0.2077
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0008 0.0073
Brugia malayi Calcitonin receptor-like protein seb-1 0.0311 0.0641 0.2142
Echinococcus multilocularis tyrosine protein kinase shark 0.0019 0.0004 0.0005
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0008 0.0012
Schistosoma mansoni tyrosine kinase 0.0019 0.0004 0.0004
Entamoeba histolytica Ran family GTPase 0.0021 0.0008 0.0016
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0019 0.0004 0.0012
Echinococcus multilocularis epidermal growth factor receptor 0.0019 0.0004 0.0005
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0033 0.0035 0.0108
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0022
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0205 0.041 0.2598
Onchocerca volvulus 0.0021 0.0007 0.0012
Brugia malayi Protein kinase domain containing protein 0.0019 0.0004 0.0012
Brugia malayi Protein kinase domain containing protein 0.0019 0.0004 0.0012
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0021 0.0059
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0021 0.0059
Echinococcus granulosus hemicentin 1 0.004 0.0049 0.0071
Schistosoma mansoni tyrosine kinase 0.0019 0.0004 0.0004
Echinococcus multilocularis geminin 0.0725 0.1548 0.2212
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0022
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0024 0.0014 0.0048
Echinococcus granulosus insulin receptor 0.0019 0.0004 0.0005
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0019 0.0004 0.0005
Echinococcus granulosus natriuretic peptide receptor 1 0.0019 0.0004 0.0005
Loa Loa (eye worm) TK/Met protein kinase 0.0019 0.0004 0.0012
Schistosoma mansoni cell adhesion molecule 0.0021 0.0007 0.0007
Schistosoma mansoni hypothetical protein 0.0024 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0196 0.0391 0.1305
Brugia malayi Tyrosine-protein kinase PR2 0.0019 0.0004 0.0012
Echinococcus granulosus activin receptor type 0.0032 0.0032 0.0046
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0021 0.0059
Brugia malayi Protein kinase domain containing protein 0.0019 0.0004 0.0012
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0021 0.0059
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0019 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0114 0.0211 0.0706
Schistosoma mansoni ran 0.0021 0.0008 0.0008
Brugia malayi serine/threonine kinase 12 0.054 0.1143 0.3818
Plasmodium falciparum tyrosine kinase-like protein 0.0019 0.0004 0.0031
Onchocerca volvulus Peroxidasin homolog 0.0021 0.0007 0.0012
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0032 0.0032 0.0096
Schistosoma mansoni tyrosine kinase 0.0059 0.0091 0.0091
Leishmania major protein kinase, putative 0.0019 0.0004 0.0012
Brugia malayi SH2 domain containing protein 0.0019 0.0004 0.0012
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0205 0.041 0.2598
Onchocerca volvulus 0.0021 0.0007 0.0011
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0308 0.0636 0.2125
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0015
Onchocerca volvulus Netrin receptor homolog 0.0021 0.0007 0.0011
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0108 0.0198 0.1231
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1112 0.2393 0.7991
Mycobacterium tuberculosis Probable lipase LipE 0.0114 0.0211 0.1317
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0021 0.0007 0.001
Mycobacterium tuberculosis Conserved protein 0.0114 0.0211 0.1317
Schistosoma mansoni nephrin related 0.0019 0.0004 0.0004
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0205 0.041 0.2598
Loa Loa (eye worm) hypothetical protein 0.0187 0.0371 0.1238
Loa Loa (eye worm) hypothetical protein 0.019 0.0378 0.1263
Entamoeba histolytica protein kinase domain containing protein 0.0032 0.0032 0.0096
Mycobacterium ulcerans DNA polymerase IV 0.0038 0.0046 0.0546
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0059 0.0091 0.0091
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0019 0.0004 0.0004
Mycobacterium tuberculosis Probable oxidoreductase 0.012 0.0225 0.1402
Trypanosoma brucei cytochrome P450, putative 0.0342 0.0711 0.2366
Brugia malayi intermediate filament protein 0.0026 0.0019 0.0064
Echinococcus granulosus tyrosine protein kinase Fyn 0.0019 0.0004 0.0005
Echinococcus multilocularis isocitrate dehydrogenase 0.0033 0.0035 0.005
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0205 0.041 0.2598
Loa Loa (eye worm) hypothetical protein 0.0039 0.0048 0.0161
Entamoeba histolytica hypothetical protein 0.0037 0.0042 0.0128
Brugia malayi serine/threonine protein kinase 6 0.054 0.1143 0.3818
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0019 0.0004 0.0012
Brugia malayi RNA, U transporter 1 0.0082 0.0142 0.0473
Onchocerca volvulus 0.0037 0.0043 0.0133
Schistosoma mansoni terminal deoxycytidyl transferase 0.0038 0.0046 0.0046
Entamoeba histolytica acyl-CoA synthetase, putative 0.0053 0.0077 0.0247
Brugia malayi bone morphogenetic protein type 1 receptor 0.0019 0.0004 0.0012
Loa Loa (eye worm) disorganized muscle protein 1 0.0021 0.0007 0.0022
Schistosoma mansoni titin 0.0021 0.0007 0.0007
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0205 0.041 0.2598
Brugia malayi Protein kinase domain containing protein 0.0019 0.0004 0.0012
Brugia malayi beta-lactamase family protein 0.0114 0.0211 0.0706
Loa Loa (eye worm) hypothetical protein 0.0038 0.0046 0.0153
Schistosoma mansoni tyrosine kinase 0.0019 0.0004 0.0004
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0008 0.0016
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0065 0.0094
Loa Loa (eye worm) hypothetical protein 0.0145 0.028 0.0934
Giardia lamblia DINP protein human, muc B family 0.0038 0.0046 0.0142
Loa Loa (eye worm) TK/EPH protein kinase 0.0019 0.0004 0.0012
Echinococcus granulosus dna polymerase eta 0.0038 0.0046 0.0066
Entamoeba histolytica hypothetical protein 0.0037 0.0042 0.0128
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0205 0.041 0.2598
Brugia malayi Protein kinase domain containing protein 0.0019 0.0004 0.0012
Echinococcus granulosus leucine rich repeat containing protein 4 0.0021 0.0007 0.001
Echinococcus granulosus mothers against decapentaplegic 5 0.0034 0.0036 0.0051
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.001 0.002
Leishmania major 4-coumarate:coa ligase-like protein 0.0053 0.0077 0.0258
Brugia malayi Protein kinase domain containing protein 0.0019 0.0004 0.0012
Echinococcus multilocularis Immunoglobulin 0.0019 0.0004 0.0006
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0033 0.0035 0.0106
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0098 0.0177 0.0253
Loa Loa (eye worm) serine/threonine protein kinase 0.0019 0.0004 0.0012
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0022
Echinococcus multilocularis smad 0.0034 0.0036 0.0051
Schistosoma mansoni hypothetical protein 0.0098 0.0177 0.0177
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0021 0.0059
Echinococcus multilocularis dna polymerase kappa 0.0038 0.0046 0.0066
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0022
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.005 0.0159
Schistosoma mansoni peroxidasin 0.002 0.0005 0.0005
Loa Loa (eye worm) MH1 domain-containing protein 0.0034 0.0036 0.0119
Echinococcus granulosus receptor type guanylyl cyclase 0.0019 0.0004 0.0005
Schistosoma mansoni roundabout 0.004 0.0049 0.0049
Brugia malayi Immunoglobulin I-set domain containing protein 0.004 0.0049 0.0165
Loa Loa (eye worm) hypothetical protein 0.019 0.0378 0.1263
Mycobacterium ulcerans DNA polymerase IV 0.0038 0.0046 0.0546
Echinococcus multilocularis GPCR, family 2 0.0098 0.0177 0.0253
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0019 0.0004 0.0005
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0021 0.0007 0.0022
Brugia malayi Importin beta-1 subunit 0.0029 0.0025 0.0084
Schistosoma mansoni hypothetical protein 0.0021 0.0007 0.0007
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0035 0.0106
Leishmania major 4-coumarate:coa ligase-like protein 0.0053 0.0077 0.0258
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0037 0.0043 0.0061
Brugia malayi Immunoglobulin I-set domain containing protein 0.019 0.0378 0.1263
Echinococcus multilocularis roundabout 2 0.0044 0.0057 0.0082
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0023 0.0012 0.0041
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.1387 0.2994 1
Loa Loa (eye worm) TK/FER protein kinase 0.0019 0.0004 0.0012
Echinococcus granulosus tyrosine protein kinase csk 0.0019 0.0004 0.0005
Echinococcus multilocularis tyrosine protein kinase csk 0.0019 0.0004 0.0005
Brugia malayi Protein kinase domain containing protein 0.0019 0.0004 0.0012
Onchocerca volvulus 0.0247 0.0502 0.1668
Echinococcus granulosus TGF beta signal transducer SmadC 0.0034 0.0036 0.0051
Loa Loa (eye worm) SRC-1 0.0019 0.0004 0.0012
Schistosoma mansoni protein kinase 0.0032 0.0032 0.0032
Brugia malayi Immunoglobulin I-set domain containing protein 0.0021 0.0007 0.0022
Brugia malayi Leucine Rich Repeat family protein 0.0021 0.0007 0.0024
Echinococcus multilocularis FL cytokine receptor 0.0019 0.0004 0.0005
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0019 0.0004 0.0005
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0019 0.0004 0.0006
Leishmania major GTP-binding protein, putative 0.0021 0.0008 0.0028
Echinococcus granulosus ubiquitin specific protease 41 0.004 0.005 0.0072
Brugia malayi Protein kinase domain containing protein 0.0019 0.0004 0.0012
Entamoeba histolytica peptidase, C54 family 0.0023 0.0012 0.0028
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.002 0.0057
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0046 0.0145
Entamoeba histolytica protein kinase domain containing protein 0.054 0.1143 0.3811
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0046 0.0145
Echinococcus multilocularis neuroglian 0.0044 0.0057 0.0082
Echinococcus multilocularis activated cdc42 kinase 1 0.0019 0.0004 0.0005
Echinococcus granulosus muscleblind protein 0.0145 0.028 0.04
Loa Loa (eye worm) hypothetical protein 0.0026 0.0019 0.0064
Onchocerca volvulus Peroxidasin homolog 0.0021 0.0007 0.0011
Brugia malayi protein-tyrosine kinase 0.0019 0.0004 0.0012
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.003 0.0027 0.0038
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0012
Schistosoma mansoni hypothetical protein 0.0098 0.0177 0.0177
Loa Loa (eye worm) TK/RYK protein kinase 0.0019 0.0004 0.0012
Schistosoma mansoni titin 0.0021 0.0007 0.0007
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0008 0.0025
Loa Loa (eye worm) hypothetical protein 0.0138 0.0263 0.0877
Leishmania major hypothetical protein, conserved 0.0114 0.0211 0.0706
Echinococcus granulosus activated cdc42 kinase 1 0.0019 0.0004 0.0005
Mycobacterium ulcerans acyl-CoA synthetase 0.0053 0.0077 0.0992
Brugia malayi Protein kinase domain containing protein 0.0019 0.0004 0.0012
Trypanosoma brucei unspecified product 0.0027 0.002 0.0057
Echinococcus granulosus epidermal growth factor receptor 0.0019 0.0004 0.0005
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0039 0.0048 0.0577
Echinococcus multilocularis Immunoglobulin 0.0187 0.037 0.0529
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0021 0.0007 0.001
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0205 0.041 0.2598
Brugia malayi MH1 domain containing protein 0.0034 0.0036 0.0119
Trypanosoma brucei Flagellum attachment zone protein 20 0.0019 0.0004 0.0003
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0042 0.0042
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0205 0.041 0.5722
Mycobacterium leprae conserved hypothetical protein 0.0114 0.0211 0.4716
Trichomonas vaginalis AGC family protein kinase 0.054 0.1143 0.3811
Echinococcus granulosus basement membrane specific heparan sulfate 0.0019 0.0004 0.0006
Schistosoma mansoni hypothetical protein 0.0019 0.0004 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0021 0.0059
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0059 0.0091 0.0291
Loa Loa (eye worm) cytochrome P450 family protein 0.0342 0.0711 0.2373
Loa Loa (eye worm) hypothetical protein 0.0039 0.0048 0.0161
Trichomonas vaginalis D-aminoacylase, putative 0.0114 0.0211 0.0695
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0044 0.0057 0.0082
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.1387 0.2994 0.428
Schistosoma mansoni slit 0.0021 0.0007 0.0007
Mycobacterium tuberculosis Probable dehydrogenase 0.0108 0.0198 0.1231
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0019 0.0004 0.0005
Toxoplasma gondii aldehyde dehydrogenase 0.0183 0.0363 0.3175
Loa Loa (eye worm) TK/FER protein kinase 0.0019 0.0004 0.0012
Trypanosoma cruzi hypothetical protein, conserved 0.0114 0.0211 0.0695
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0008 0.0012
Loa Loa (eye worm) CAMK protein kinase 0.0037 0.0043 0.0145
Loa Loa (eye worm) RGC/RGC protein kinase 0.0019 0.0004 0.0012
Echinococcus granulosus titin 0.0021 0.0007 0.001
Loa Loa (eye worm) TK/EGFR protein kinase 0.0019 0.0004 0.0012
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0116 0.0215 0.0307
Loa Loa (eye worm) hypothetical protein 0.004 0.0049 0.0165
Loa Loa (eye worm) TK protein kinase 0.0019 0.0004 0.0012
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0034 0.0036 0.0036
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0848 0.1816 0.2596
Brugia malayi Guanylyl cyclase protein 23 0.0019 0.0004 0.0012
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0038 0.0046 0.0066
Schistosoma mansoni cpg binding protein 0.012 0.0224 0.0224
Schistosoma mansoni hypothetical protein 0.0021 0.0007 0.0007
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0065 0.0207
Schistosoma mansoni tyrosine kinase 0.0019 0.0004 0.0004
Echinococcus multilocularis tyrosine protein kinase HCK 0.0019 0.0004 0.0005
Echinococcus multilocularis Immunoglobulin 0.0019 0.0004 0.0006
Schistosoma mansoni cell adhesion molecule 0.0044 0.0057 0.0057
Brugia malayi Protein kinase domain containing protein 0.0019 0.0004 0.0012
Loa Loa (eye worm) hypothetical protein 0.0039 0.0048 0.0161
Schistosoma mansoni intermediate filament proteins 0.0026 0.0019 0.0019
Echinococcus multilocularis tyrosine protein kinase otk 0.004 0.0049 0.0071
Loa Loa (eye worm) TK/ACK protein kinase 0.0019 0.0004 0.0012
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0205 0.041 0.2598
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0187 0.037 0.0529
Brugia malayi Isocitrate dehydrogenase 0.0033 0.0035 0.0117
Trichomonas vaginalis helicase, putative 0.0027 0.0021 0.0059
Schistosoma mansoni nephrin 0.0211 0.0423 0.0423
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0043 0.0131
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0019 0.0004 0.0002
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0205 0.041 0.5722
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0043 0.0134
Brugia malayi Fibronectin type III domain containing protein 0.019 0.0378 0.1263
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0205 0.041 0.5722
Schistosoma mansoni aldehyde dehydrogenase 0.0183 0.0363 0.0363
Schistosoma mansoni netrin receptor unc5 0.0019 0.0004 0.0004
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0019 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.004 0.0049 0.0165
Brugia malayi Immunoglobulin I-set domain containing protein 0.0021 0.0007 0.0022
Loa Loa (eye worm) TK protein kinase 0.0019 0.0004 0.0012
Brugia malayi cytochrome P450 0.0205 0.041 0.1369
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.004 0.0049 0.0165
Leishmania major cytochrome p450-like protein 0.0205 0.041 0.1369
Echinococcus multilocularis heat shock protein 70 0.0019 0.0004 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.001 0.002
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0019 0.0004 0.0005
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0023 0.0012 0.0017
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0019 0.0004 0.0031
Schistosoma mansoni hypothetical protein 0.0212 0.0426 0.0426
Schistosoma mansoni tyrosine kinase 0.0019 0.0004 0.0004
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0116 0.0215 0.0307
Echinococcus multilocularis raf serine:threonine protein kinase 0.0019 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0015
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0019 0.0004 0.0005
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0032 0.0032 0.0096
Schistosoma mansoni tyrosine kinase 0.0019 0.0004 0.0004
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0008 0.0019
Loa Loa (eye worm) TK/FER protein kinase 0.0019 0.0004 0.0012
Brugia malayi Protein kinase domain containing protein 0.0019 0.0004 0.0012
Brugia malayi serine/threonine-protein kinase 6 0.054 0.1143 0.3818
Onchocerca volvulus 0.0114 0.0211 0.0695
Trichomonas vaginalis penicillin-binding protein, putative 0.0114 0.0211 0.0695
Trichomonas vaginalis penicillin-binding protein, putative 0.0114 0.0211 0.0695
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0021 0.0059
Echinococcus granulosus neuropeptide s receptor 0.151 0.3264 0.4665
Loa Loa (eye worm) animal heme peroxidase 0.0021 0.0007 0.0022
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0388 0.0809 0.1157
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0008 0.5
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0039 0.0048 0.0262
Schistosoma mansoni tyrosine kinase 0.0019 0.0004 0.0004
Mycobacterium tuberculosis Probable reductase 0.0108 0.0198 0.1231
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0021 0.0007 0.0022
Echinococcus multilocularis microtubule associated protein 2 0.0722 0.154 0.2201
Loa Loa (eye worm) hypothetical protein 0.0024 0.0014 0.0048
Schistosoma mansoni cell adhesion molecule 0.021 0.0421 0.0421
Loa Loa (eye worm) hypothetical protein 0.0114 0.0211 0.0706
Echinococcus granulosus Immunoglobulin 0.0187 0.037 0.0529
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0008 0.0016
Leishmania major cytochrome p450-like protein 0.0205 0.041 0.1369
Brugia malayi Tyrosine-protein kinase abl-1 0.0019 0.0004 0.0012
Brugia malayi AMP-binding enzyme family protein 0.0053 0.0077 0.0258
Brugia malayi Immunoglobulin I-set domain containing protein 0.0037 0.0043 0.0145
Brugia malayi N-terminal motif family protein 0.0196 0.0391 0.1305
Loa Loa (eye worm) hypothetical protein 0.0092 0.0163 0.0543
Echinococcus granulosus cysteine protease atg4b 0.0059 0.0091 0.0129
Echinococcus multilocularis titin 0.0021 0.0007 0.001
Echinococcus multilocularis lamin dm0 0.0026 0.0019 0.0028
Loa Loa (eye worm) hypothetical protein 0.0114 0.0211 0.0706
Onchocerca volvulus 0.0021 0.0007 0.0011
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.012 0.0225 0.5067
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0205 0.041 0.2598
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0019 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.004 0.0049 0.0165
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0019 0.0004 0.0005
Brugia malayi SH2 domain containing protein 0.0019 0.0004 0.0012
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0012
Echinococcus multilocularis muscleblind protein 1 0.0145 0.028 0.04
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0057 0.0086 0.0287
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0024 0.0014 0.0021
Echinococcus multilocularis tyrosine protein kinase Blk 0.0019 0.0004 0.0005
Onchocerca volvulus 0.0021 0.0007 0.0011
Brugia malayi Smad1 0.0034 0.0036 0.0119
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0008 0.0016
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0035 0.0307
Trypanosoma brucei DNA polymerase eta, putative 0.0038 0.0046 0.0145
Schistosoma mansoni smad1 5 8 and 0.0034 0.0036 0.0036
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0043 0.0232
Brugia malayi Immunoglobulin I-set domain containing protein 0.0024 0.0014 0.0048
Echinococcus granulosus ephrin type A receptor 4 A 0.0019 0.0004 0.0005
Schistosoma mansoni tyrosine kinase 0.0019 0.0004 0.0004
Brugia malayi Immunoglobulin domain containing protein 0.0019 0.0004 0.0015
Echinococcus multilocularis neuropeptide receptor A26 0.151 0.3264 0.4665
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0254 0.0517 0.0517
Schistosoma mansoni protein kinase 0.0019 0.0004 0.0004
Onchocerca volvulus Serine\/threonine kinase homolog 0.1387 0.2994 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0049 0.0165
Schistosoma mansoni protein kinase 0.0032 0.0032 0.0032
Brugia malayi hypothetical protein 0.0772 0.1651 0.5512
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0043 0.0143
Schistosoma mansoni hypothetical protein 0.0205 0.041 0.041
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0114 0.0211 0.29
Trichomonas vaginalis AGC family protein kinase 0.054 0.1143 0.3811
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0046 0.0142
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0019 0.0004 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.001 0.002
Onchocerca volvulus 0.0021 0.0007 0.0011
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.004 0.005 0.0156
Schistosoma mansoni hypothetical protein 0.0021 0.0007 0.0007
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0205 0.041 0.5722
Schistosoma mansoni septate junction protein 0.004 0.0049 0.0049
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0059 0.0091 0.0291
Mycobacterium leprae Conserved hypothetical protein 0.0205 0.041 1
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0019 0.0004 0.0006
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0021 0.0059
Echinococcus multilocularis cysteine protease atg4b 0.0059 0.0091 0.0129
Schistosoma mansoni tyrosine kinase 0.0019 0.0004 0.0004
Onchocerca volvulus 0.0021 0.0007 0.0011
Brugia malayi Peptidase family C54 containing protein 0.0059 0.0091 0.0302
Brugia malayi Prion-like- 0.0021 0.0007 0.0022
Schistosoma mansoni ephrin receptor 0.0023 0.0011 0.0011
Brugia malayi basement membrane proteoglycan 0.0019 0.0004 0.0015
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0032 0.0032 0.0046
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0108 0.0198 0.1231
Schistosoma mansoni ran 0.0021 0.0008 0.0008
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0205 0.041 0.2598
Plasmodium falciparum protein kinase, putative 0.0032 0.0032 0.0283
Schistosoma mansoni hemicentin 0.0024 0.0014 0.0014
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0046 0.0142
Echinococcus granulosus tyrosine protein kinase otk 0.004 0.0049 0.0071
Trichomonas vaginalis D-aminoacylase, putative 0.0114 0.0211 0.0695
Brugia malayi Protein kinase domain containing protein 0.0019 0.0004 0.0012
Schistosoma mansoni tyrosine protein kinase 0.0019 0.0004 0.0004
Entamoeba histolytica hypothetical protein 0.0019 0.0004 0.0002
Brugia malayi protein unc-22 0.0037 0.0043 0.0145
Echinococcus granulosus Immunoglobulin subtype 0.0019 0.0004 0.0006
Loa Loa (eye worm) TK protein kinase 0.0019 0.0004 0.0012
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0022
Schistosoma mansoni hypothetical protein 0.1706 0.369 0.369
Loa Loa (eye worm) TK/FER protein kinase 0.0019 0.0004 0.0012
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0388 0.0809 0.1157
Schistosoma mansoni cpg binding protein 0.0127 0.0239 0.0239
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0205 0.041 0.2598
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.054 0.1143 0.3811
Plasmodium vivax acyl-CoA synthetase, putative 0.0039 0.0048 0.0391
Entamoeba histolytica deoxycytidyl transferase, putative 0.0038 0.0046 0.0142
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0311 0.0641 0.2142
Schistosoma mansoni cpg binding protein 0.0127 0.0239 0.0239
Schistosoma mansoni septate junction protein 0.004 0.0049 0.0049
Schistosoma mansoni smad 0.0034 0.0036 0.0036
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0008 0.0016
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0019 0.0004 0.0012
Schistosoma mansoni lamin 0.0026 0.0019 0.0019
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0034 0.0173
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0008 0.0066
Loa Loa (eye worm) hypothetical protein 0.0114 0.0211 0.0706
Brugia malayi hypothetical protein 0.0019 0.0004 0.0012
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0022
Schistosoma mansoni cell adhesion molecule 0.0044 0.0057 0.0057
Onchocerca volvulus 0.0021 0.0007 0.0011
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0038 0.0046 0.0046
Trypanosoma brucei polo-like protein kinase 0.1387 0.2994 1
Echinococcus multilocularis Immunoglobulin 0.0187 0.037 0.0529
Loa Loa (eye worm) hypothetical protein 0.0114 0.0211 0.0706
Schistosoma mansoni titin 0.0021 0.0007 0.0007
Giardia lamblia Aurora kinase 0.054 0.1143 0.3811
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0043 0.0131
Loa Loa (eye worm) isocitrate dehydrogenase 0.0033 0.0035 0.0117
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0043 0.0374
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0035 0.005
Loa Loa (eye worm) TK protein kinase 0.0019 0.0004 0.0012
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0004 0.0004
Mycobacterium tuberculosis Probable lipase LipD 0.0114 0.0211 0.1317
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0008 0.0025
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.004 0.0134
Schistosoma mansoni netrin receptor unc5 0.0019 0.0004 0.0004
Toxoplasma gondii thioredoxin reductase 0.0047 0.0065 0.0573
Echinococcus multilocularis epidermal growth factor receptor 0.0019 0.0004 0.0005
Trichomonas vaginalis CAMK family protein kinase 0.1387 0.2994 1
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0019 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.0061
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0114 0.0211 0.1317
Trichomonas vaginalis glutaminase, putative 0.0302 0.0622 0.2067
Echinococcus multilocularis mixed lineage leukemia protein mll 0.003 0.0027 0.0038
Mycobacterium tuberculosis Conserved protein 0.0114 0.0211 0.1317
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0183 0.0363 0.0519
Trypanosoma cruzi DNA polymerase eta, putative 0.0038 0.0046 0.0142
Brugia malayi hypothetical protein 0.0019 0.0004 0.0015
Loa Loa (eye worm) TK protein kinase 0.0019 0.0004 0.0012
Brugia malayi MH2 domain containing protein 0.0034 0.0036 0.0119
Leishmania major 4-coumarate:coa ligase-like protein 0.0053 0.0077 0.0258
Brugia malayi Protein kinase domain containing protein 0.0019 0.0004 0.0012
Brugia malayi Immunoglobulin I-set domain containing protein 0.0136 0.026 0.0868
Plasmodium falciparum importin beta, putative 0.0029 0.0025 0.0219
Schistosoma mansoni neuroglian 0.0044 0.0057 0.0057
Brugia malayi Disorganized muscle protein 1 0.0021 0.0007 0.0022
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0019 0.0004 0.0005
Echinococcus multilocularis tyrosine protein kinase csk 0.0019 0.0004 0.0005
Echinococcus multilocularis receptor type guanylyl cyclase 0.0019 0.0004 0.0005
Schistosoma mansoni hypothetical protein 0.0725 0.1548 0.1548
Echinococcus multilocularis beta LACTamase domain containing family member 0.0114 0.0211 0.0302
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0022
Brugia malayi Protein kinase domain containing protein 0.0019 0.0004 0.0012
Entamoeba histolytica hypothetical protein 0.0037 0.0042 0.0128
Loa Loa (eye worm) hypothetical protein 0.0212 0.0426 0.1424
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0035 0.005
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0388 0.0809 0.0809
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.005 0.0156
Echinococcus granulosus neuroglian 0.0207 0.0415 0.0593
Schistosoma mansoni cell adhesion molecule 0.0019 0.0004 0.0004
Brugia malayi Animal haem peroxidase family protein 0.0021 0.0007 0.0022
Echinococcus granulosus tyrosine protein kinase Fyn 0.0019 0.0004 0.0005
Echinococcus granulosus kinase suppressor of Ras 1 0.0019 0.0004 0.0005
Schistosoma mansoni tyrosine kinase 0.0019 0.0004 0.0004
Echinococcus granulosus titin 0.0021 0.0007 0.001
Echinococcus multilocularis integrin linked protein kinase 0.0019 0.0004 0.0005
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0388 0.0809 0.1157
Onchocerca volvulus 0.002 0.0005 0.0004
Brugia malayi Protein kinase domain containing protein 0.0019 0.0004 0.0012
Plasmodium falciparum thioredoxin reductase 0.0047 0.0065 0.0573
Entamoeba histolytica serine/threonine protein kinase, putative 0.1387 0.2994 1
Echinococcus granulosus protein tyrosine kinase 0.0019 0.0004 0.0005
Entamoeba histolytica peptidase, C54 family 0.0023 0.0012 0.0028
Brugia malayi Protein kinase domain containing protein 0.0019 0.0004 0.0012
Echinococcus granulosus aurora kinase A 0.054 0.1143 0.1634
Echinococcus granulosus tyrosine protein kinase Blk 0.0019 0.0004 0.0005
Schistosoma mansoni tyrosine kinase 0.0019 0.0004 0.0004
Plasmodium vivax glutathione reductase, putative 0.0047 0.0065 0.0544
Brugia malayi CXXC zinc finger family protein 0.012 0.0224 0.0747
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0059 0.0091 0.0291
Mycobacterium leprae Probable lipase LipE 0.0114 0.0211 0.4716
Schistosoma mansoni vesicular amine transporter 0.0187 0.037 0.037
Loa Loa (eye worm) hypothetical protein 0.0311 0.0641 0.2142
Trypanosoma brucei aurora B kinase 0.054 0.1143 0.3812
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.002 0.0057
Loa Loa (eye worm) TK/FER protein kinase 0.0019 0.0004 0.0012
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0019 0.0004 0.0012
Entamoeba histolytica protein kinase, putative 0.054 0.1143 0.3811
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0098 0.0177 0.0253
Schistosoma mansoni tyrosine kinase 0.0019 0.0004 0.0004
Onchocerca volvulus 0.0158 0.0306 0.1012
Toxoplasma gondii STE kinase 0.0019 0.0004 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.001 0.002
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0205 0.041 0.5722
Echinococcus granulosus neuroglian 0.0044 0.0057 0.0082
Echinococcus multilocularis c src tyrosine kinase 0.0019 0.0004 0.0005
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0013 0.0032
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0046 0.0145
Echinococcus multilocularis roundabout 2 0.023 0.0466 0.0665
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0042 0.006
Trichomonas vaginalis CAMK family protein kinase 0.1387 0.2994 1
Brugia malayi ImpB/MucB/SamB family protein 0.0038 0.0046 0.0153
Plasmodium vivax serine/threonine protein kinase 6, putative 0.054 0.1143 1
Echinococcus multilocularis hemicentin 1 0.004 0.0049 0.0071
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0206 0.0413 0.059
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0008 0.0028
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0019 0.0004 0.0005
Trichomonas vaginalis AGC family protein kinase 0.054 0.1143 0.3811
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0187 0.037 0.037
Mycobacterium tuberculosis Probable hydrolase 0.0114 0.0211 0.1317
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.004 0.0049 0.0165
Brugia malayi Cytochrome P450 family protein 0.0205 0.041 0.1369
Entamoeba histolytica protein kinase, putative 0.054 0.1143 0.3811
Brugia malayi Cytochrome P450 family protein 0.0342 0.0711 0.2373
Schistosoma mansoni hypothetical protein 0.0021 0.0007 0.0007
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0205 0.041 0.5722
Toxoplasma gondii aurora kinase 0.054 0.1143 1
Mycobacterium ulcerans lipase LipD 0.0114 0.0211 0.29
Brugia malayi ImpB/MucB/SamB family protein 0.0038 0.0046 0.0153
Onchocerca volvulus Phospholipase A2 homolog 0.0436 0.0915 0.3048
Loa Loa (eye worm) one IG domain family member 0.0021 0.0007 0.0022
Toxoplasma gondii cytochrome p450 superfamily protein 0.0205 0.041 0.3585
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0311 0.0641 0.2142
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0059 0.0091 0.0091
Echinococcus granulosus raf serine:threonine protein kinase 0.0019 0.0004 0.0005
Schistosoma mansoni hypothetical protein 0.0019 0.0004 0.0004
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0205 0.041 0.2598
Schistosoma mansoni aldehyde dehydrogenase 0.0183 0.0363 0.0363
Brugia malayi Peroxidasin 0.004 0.005 0.0166
Schistosoma mansoni ephrin receptor 0.0019 0.0004 0.0004
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0205 0.041 0.5722
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0046 0.0145
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0043 0.0232
Leishmania major cytochrome p450-like protein 0.0342 0.0711 0.2373
Schistosoma mansoni tyrosine kinase 0.0019 0.0004 0.0004
Echinococcus multilocularis kinase suppressor of Ras 1 0.0019 0.0004 0.0005
Echinococcus multilocularis neuroglian 0.0207 0.0415 0.0593
Trichomonas vaginalis CAMK family protein kinase 0.1387 0.2994 1
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0205 0.041 0.2598
Echinococcus granulosus dna polymerase kappa 0.0038 0.0046 0.0066
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0038 0.0046 0.0153
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0205 0.041 0.5722
Echinococcus multilocularis tyrosine protein kinase 0.0019 0.0004 0.0005
Brugia malayi basement membrane proteoglycan precursor 0.0019 0.0004 0.0015
Onchocerca volvulus 0.0887 0.19 0.6341
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0019 0.0004 0.0004
Echinococcus granulosus tyrosine kinase 0.0019 0.0004 0.0005
Brugia malayi Immunoglobulin I-set domain containing protein 0.0021 0.0007 0.0022
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0013 0.0032
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0183 0.0363 0.0519
Onchocerca volvulus 0.0114 0.0211 0.0695
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0114 0.0211 0.1317
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0019 0.0004 0.0012
Schistosoma mansoni hypothetical protein 0.0021 0.0007 0.0007
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0008 0.0013
Schistosoma mansoni tyrosine kinase 0.0019 0.0004 0.0004
Schistosoma mansoni mixed-lineage leukemia protein mll 0.003 0.0027 0.0027
Brugia malayi Immunoglobulin I-set domain containing protein 0.0021 0.0007 0.0022
Schistosoma mansoni ap endonuclease 0.0021 0.0008 0.0008
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.005 0.0156
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0008 0.0013
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.004 0.005 0.0072
Brugia malayi Inositol-1 0.0037 0.0043 0.0143
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0015
Brugia malayi Immunoglobulin domain containing protein 0.0019 0.0004 0.0015
Echinococcus multilocularis ubiquitin specific protease 41 0.004 0.005 0.0072
Mycobacterium ulcerans aldehyde dehydrogenase 0.0183 0.0363 0.5056
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0114 0.0211 0.0706
Loa Loa (eye worm) TK protein kinase 0.0019 0.0004 0.0012
Echinococcus multilocularis netrin receptor unc 5 0.0019 0.0004 0.0006
Loa Loa (eye worm) MH2 domain-containing protein 0.0494 0.1043 0.3483
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0019 0.0004 0.0004
Echinococcus multilocularis Immunoglobulin subtype 0.0019 0.0004 0.0006
Schistosoma mansoni hypothetical protein 0.0098 0.0177 0.0177
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0022
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0021 0.0007 0.0022
Loa Loa (eye worm) hypothetical protein 0.0039 0.0048 0.0161
Echinococcus multilocularis protein KINase family member (kin 25) 0.0019 0.0004 0.0005
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0205 0.041 0.1358
Schistosoma mansoni inositol monophosphatase 0.0037 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0022
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0044 0.0057 0.0082
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0729 0.1556 1
Trypanosoma brucei protein kinase, putative 0.0032 0.0032 0.0099
Brugia malayi Immunoglobulin I-set domain containing protein 0.004 0.0049 0.0165
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0019 0.0004 0.0004
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0116 0.0215 0.0307
Echinococcus granulosus cpg binding protein 0.0127 0.0239 0.0341
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0059 0.0091 0.0291
Echinococcus granulosus GPCR family 2 0.0098 0.0177 0.0253
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0342 0.0711 1
Brugia malayi hypothetical protein 0.0022 0.001 0.0032
Echinococcus granulosus tyrosine kinase 0.0019 0.0004 0.0005
Brugia malayi Prion-like- 0.0021 0.0007 0.0022
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0205 0.041 0.1361
Loa Loa (eye worm) transcription factor SMAD2 0.0494 0.1043 0.3483
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0019 0.0004 0.0012
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0019 0.0004 0.0005
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0183 0.0363 0.2295
Brugia malayi Immunoglobulin I-set domain containing protein 0.0021 0.0007 0.0022
Loa Loa (eye worm) nuclear factor I 0.0019 0.0003 0.0009
Mycobacterium leprae putative cytochrome p450 0.0205 0.041 1
Schistosoma mansoni hypothetical protein 0.0021 0.0007 0.0007
Loa Loa (eye worm) TK/FER protein kinase 0.0019 0.0004 0.0012
Echinococcus multilocularis survival motor neuron protein 1 0.0772 0.1651 0.2359
Brugia malayi C-terminal src kinase protein 1 0.0019 0.0004 0.0012
Mycobacterium ulcerans beta-lactamase 0.0114 0.0211 0.29
Brugia malayi Immunoglobulin I-set domain containing protein 0.0021 0.0007 0.0022
Schistosoma mansoni tyrosine kinase 0.0019 0.0004 0.0004
Loa Loa (eye worm) cytochrome P450 0.0205 0.041 0.1369
Echinococcus multilocularis tyrosine kinase 0.0019 0.0004 0.0005
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0019 0.0004 0.0004
Echinococcus granulosus survival motor neuron protein 1 0.0772 0.1651 0.2359
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0008 0.0073
Loa Loa (eye worm) CXXC zinc finger family protein 0.012 0.0224 0.0747
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.054 0.1143 0.1634
Mycobacterium tuberculosis Conserved hypothetical protein 0.0038 0.0046 0.0248
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.004 0.0048 0.0069
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0019 0.0004 0.0005
Echinococcus multilocularis protein kinase 0.0019 0.0004 0.0005
Mycobacterium ulcerans esterase/lipase LipP 0.0114 0.0211 0.29
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0183 0.0363 0.1212
Echinococcus granulosus Immunoglobulin 0.0019 0.0004 0.0006
Echinococcus granulosus nephrin 0.0024 0.0014 0.0021
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0019 0.0004 0.0012
Loa Loa (eye worm) TK protein kinase 0.0019 0.0004 0.0012
Plasmodium falciparum protein kinase, putative 0.0019 0.0004 0.0031
Brugia malayi beta-lactamase 0.0114 0.0211 0.0706
Trichomonas vaginalis esterase, putative 0.0114 0.0211 0.0695
Schistosoma mansoni septate junction protein 0.0019 0.0004 0.0004
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0205 0.041 0.5722
Echinococcus multilocularis titin 0.0037 0.0043 0.0062
Trichomonas vaginalis D-aminoacylase, putative 0.0114 0.0211 0.0695
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0053 0.0077 0.0992
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.004 0.005 0.0156
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0038 0.0046 0.0153
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0021 0.0007 0.001
Mycobacterium ulcerans acyl-CoA synthetase 0.0053 0.0077 0.0992
Brugia malayi Immunoglobulin I-set domain containing protein 0.004 0.0049 0.0165
Loa Loa (eye worm) beta-lactamase 0.0114 0.0211 0.0706
Echinococcus granulosus serine:threonine protein kinase PLK1 0.1387 0.2994 0.428
Brugia malayi Immunoglobulin I-set domain containing protein 0.0021 0.0007 0.0022
Schistosoma mansoni tyrosine kinase 0.0019 0.0004 0.0004
Loa Loa (eye worm) TK/FER protein kinase 0.0019 0.0004 0.0012
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.004 0.005 0.0072
Schistosoma mansoni myosin-binding protein-related 0.0024 0.0014 0.0014
Onchocerca volvulus Basement membrane proteoglycan homolog 0.004 0.0049 0.0153
Echinococcus granulosus retinal guanylyl cyclase 2 0.0019 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0012
Brugia malayi Protein kinase domain containing protein 0.0019 0.0004 0.0012
Schistosoma mansoni protein kinase 0.0032 0.0032 0.0032
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0046 0.0145
Schistosoma mansoni hypothetical protein 0.0098 0.0177 0.0177
Onchocerca volvulus 0.0022 0.001 0.002
Brugia malayi Protein kinase domain containing protein 0.0019 0.0004 0.0012
Entamoeba histolytica hypothetical protein 0.0019 0.0004 0.0002
Schistosoma mansoni titin 0.0037 0.0043 0.0043
Trichomonas vaginalis CAMK family protein kinase 0.1387 0.2994 1
Schistosoma mansoni cell adhesion molecule 0.004 0.0049 0.0049
Mycobacterium ulcerans acyl-CoA synthetase 0.0053 0.0077 0.0992
Toxoplasma gondii autophagy-related cysteine peptidase atg4, putative 0.0023 0.0012 0.0105
Echinococcus multilocularis activin receptor type 0.0032 0.0032 0.0046
Echinococcus granulosus tyrosine protein kinase Lyn 0.0032 0.0032 0.0046
Schistosoma mansoni tyrosine kinase 0.0019 0.0004 0.0004
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0043 0.0232
Onchocerca volvulus 0.012 0.0224 0.0736
Loa Loa (eye worm) AUR protein kinase 0.054 0.1143 0.3818
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0019 0.0004 0.0005
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0019 0.0004 0.0012
Schistosoma mansoni basigin related 0.0019 0.0004 0.0004
Echinococcus granulosus retinal guanylyl cyclase 2 0.0019 0.0004 0.0005
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0019 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0024 0.0014 0.0048
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0205 0.041 0.2598
Loa Loa (eye worm) TK/FAK protein kinase 0.0019 0.0004 0.0012
Echinococcus granulosus roundabout 2 0.0044 0.0057 0.0082
Trypanosoma cruzi aurora B kinase, putative 0.054 0.1143 0.3811
Schistosoma mansoni hypothetical protein 0.0725 0.1548 0.1548
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0012
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0187 0.037 0.037
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0059 0.0091 0.0291
Trypanosoma cruzi cysteine peptidase, Clan CA, family C54, putative 0.0023 0.0012 0.0028
Schistosoma mansoni importin beta-1 0.0029 0.0025 0.0025
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0008 0.0011
Echinococcus granulosus down syndrome cell adhesion 0.0021 0.0007 0.001
Brugia malayi Cytochrome P450 family protein 0.0342 0.0711 0.2373
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.054 0.1143 0.3811
Entamoeba histolytica hypothetical protein 0.0019 0.0004 0.0002
Entamoeba histolytica peptidase, C54 family 0.0023 0.0012 0.0028
Schistosoma mansoni hypothetical protein 0.0019 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0206 0.0413 0.1379
Schistosoma mansoni basigin related 0.0019 0.0004 0.0004
Echinococcus multilocularis lamin 0.0026 0.0019 0.0028
Trypanosoma brucei Pseudokinase, putative 0.0019 0.0004 0.0003
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0024 0.0014 0.0048
Loa Loa (eye worm) hypothetical protein 0.0019 0.0003 0.0009
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0205 0.041 0.5722
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0046 0.0145
Entamoeba histolytica peptidase, C54 family 0.0059 0.0091 0.0291
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.005 0.0156
Giardia lamblia Kinase, PLK 0.1387 0.2994 1
Brugia malayi hypothetical protein 0.019 0.0378 0.1263
Loa Loa (eye worm) TK/FER protein kinase 0.0019 0.0004 0.0012
Trichomonas vaginalis CAMK family protein kinase 0.1387 0.2994 1
Schistosoma mansoni protein kinase 0.0019 0.0004 0.0004
Loa Loa (eye worm) TK protein kinase 0.0019 0.0004 0.0012
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0043 0.0502
Schistosoma mansoni hypothetical protein 0.0019 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0145 0.028 0.0934
Trypanosoma cruzi polo-like protein kinase, putative 0.1387 0.2994 1
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0021 0.0007 0.0022
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0021 0.0059
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0025 0.0075
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.012 0.0225 0.1402
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0046 0.0142
Entamoeba histolytica acyl-coA synthetase, putative 0.0053 0.0077 0.0247
Echinococcus granulosus netrin receptor unc 5 0.0019 0.0004 0.0006
Echinococcus multilocularis dnaJ subfamily B 0.1706 0.369 0.5275
Trypanosoma brucei AUT2/APG4/ATG4 cysteine peptidase, putative 0.0059 0.0091 0.0294
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0021 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0012
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0019 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0012
Echinococcus multilocularis natriuretic peptide receptor 1 0.0019 0.0004 0.0005
Brugia malayi Protein kinase domain containing protein 0.0019 0.0004 0.0012
Leishmania major DNA polymerase eta, putative 0.0038 0.0046 0.0153
Brugia malayi Immunoglobulin I-set domain containing protein 0.004 0.0049 0.0165
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0012
Leishmania major protein kinase, putative 0.054 0.1143 0.3818
Trypanosoma brucei unspecified product 0.0038 0.0046 0.0145
Loa Loa (eye worm) TK/FER protein kinase 0.0019 0.0004 0.0012
Schistosoma mansoni lamin 0.0026 0.0019 0.0019
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0025 0.0075
Plasmodium falciparum cysteine protease ATG4, putative 0.0023 0.0012 0.0105
Schistosoma mansoni ap endonuclease 0.0021 0.0008 0.0008
Schistosoma mansoni DNA polymerase eta 0.0038 0.0046 0.0046
Leishmania major trypanothione reductase 0.0047 0.0065 0.0219
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.004 0.005 0.0072
Loa Loa (eye worm) TK/FER protein kinase 0.0019 0.0004 0.0012
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.004 0.005 0.005
Loa Loa (eye worm) inositol-1 0.0037 0.0043 0.0143
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0388 0.0809 0.2702
Plasmodium falciparum protein kinase, putative 0.0019 0.0004 0.0031
Brugia malayi Myb-like DNA-binding domain containing protein 0.0021 0.0007 0.0022
Loa Loa (eye worm) hypothetical protein 0.019 0.0378 0.1263
Echinococcus granulosus Smad4 0.0034 0.0036 0.0051
Echinococcus multilocularis roundabout 2 0.0044 0.0057 0.0082
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0205 0.041 0.2598
Echinococcus multilocularis tyrosine protein kinase pr2 0.0019 0.0004 0.0005
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0034 0.0036 0.0051
Loa Loa (eye worm) AUR protein kinase 0.054 0.1143 0.3818
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0033 0.0035 0.005
Echinococcus granulosus tyrosine protein kinase HCK 0.0019 0.0004 0.0005
Brugia malayi Protein kinase domain containing protein 0.0019 0.0004 0.0012
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0059 0.0091 0.0291
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0013 0.0032
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0196 0.0391 0.1295
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0388 0.0809 0.0809
Mycobacterium ulcerans aldehyde dehydrogenase 0.0183 0.0363 0.5056
Loa Loa (eye worm) RGC/RGC protein kinase 0.0019 0.0004 0.0012
Echinococcus granulosus integrin linked protein kinase 0.0019 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0022
Echinococcus granulosus lachesin 0.004 0.0049 0.0071
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0019 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0021 0.0059
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0037 0.0043 0.0061
Trypanosoma brucei hypothetical protein, conserved 0.0114 0.0211 0.0698
Echinococcus granulosus defective proboscis extension response 0.0187 0.037 0.0529
Echinococcus multilocularis 0.0021 0.0007 0.001
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0019 0.0064
Onchocerca volvulus Phospholipase A2 homolog 0.0092 0.0163 0.0532
Brugia malayi Immunoglobulin I-set domain containing protein 0.0044 0.0057 0.019
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0205 0.041 0.5722
Echinococcus granulosus tyrosine protein kinase Fyn 0.0019 0.0004 0.0005
Echinococcus granulosus c src tyrosine kinase 0.0019 0.0004 0.0005
Entamoeba histolytica acyl-CoA synthetase, putative 0.0053 0.0077 0.0247
Echinococcus multilocularis muscleblind protein 0.0145 0.028 0.04
Loa Loa (eye worm) latrophilin receptor protein 2 0.0098 0.0177 0.0591
Plasmodium vivax importin-beta 2, putative 0.0029 0.0025 0.0189
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0053 0.0077 0.045
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0033 0.0035 0.0178
Onchocerca volvulus Tyrosine kinase homolog 0.0926 0.1986 0.663
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0019 0.0004 0.0005
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0008 0.0028
Schistosoma mansoni inositol monophosphatase 0.0037 0.0043 0.0043
Trypanosoma brucei trypanothione reductase 0.0047 0.0065 0.021
Plasmodium falciparum tyrosine kinase-like protein 0.0019 0.0004 0.0031
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0035 0.0307
Brugia malayi Immunoglobulin I-set domain containing protein 0.0024 0.0014 0.0048
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0019 0.0004 0.0004
Brugia malayi AMP-binding enzyme family protein 0.0053 0.0077 0.0258
Schistosoma mansoni hypothetical protein 0.0037 0.0042 0.0042
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.012 0.0225 0.1402
Echinococcus granulosus smad 0.0034 0.0036 0.0051
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0205 0.041 0.1369
Loa Loa (eye worm) glutaminase 0.0302 0.0622 0.2077
Schistosoma mansoni serine/threonine protein kinase 0.0037 0.0043 0.0043
Brugia malayi Protein kinase domain containing protein 0.0019 0.0004 0.0012
Schistosoma mansoni serine/threonine protein kinase 0.054 0.1143 0.1143
Loa Loa (eye worm) TK/FER protein kinase 0.0019 0.0004 0.0012
Toxoplasma gondii exonuclease III APE 0.0021 0.0008 0.0066
Schistosoma mansoni protein kinase 0.054 0.1143 0.1143
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0036 0.004 0.0134
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0035 0.0108
Echinococcus granulosus tyrosine protein kinase csk 0.0019 0.0004 0.0005
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0388 0.0809 0.1157
Brugia malayi Immunoglobulin I-set domain containing protein 0.002 0.0005 0.0017
Onchocerca volvulus 0.0053 0.0077 0.0247
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0004 0.0015
Schistosoma mansoni hypothetical protein 0.0019 0.0004 0.0004
Loa Loa (eye worm) cytochrome P450 family protein 0.0804 0.172 0.5743
Brugia malayi hypothetical protein 0.0019 0.0004 0.0012
Brugia malayi Muscleblind-like protein 0.0145 0.028 0.0934
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0019 0.0004 0.0004
Brugia malayi isocitrate dehydrogenase 0.0033 0.0035 0.0117
Schistosoma mansoni tyrosine kinase 0.0019 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0114 0.0211 0.0706
Echinococcus granulosus fibroblast growth factor receptor 4 0.0116 0.0215 0.0307
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.004 0.0049 0.0049
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0019 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.004 0.0049 0.0165
Leishmania major hypothetical protein, conserved 0.0019 0.0004 0.0012
Brugia malayi Prion-like- 0.0021 0.0007 0.0022
Schistosoma mansoni tyrosine kinase 0.0019 0.0004 0.0004
Loa Loa (eye worm) LAD-2 short isoform 0.0019 0.0004 0.0015
Loa Loa (eye worm) hypothetical protein 0.0053 0.0077 0.0258
Schistosoma mansoni serine/threonine RGC 0.0019 0.0004 0.0004
Schistosoma mansoni protein tyrosine kinase 0.0019 0.0004 0.0004
Echinococcus granulosus cytochrome P450 2K1 0.0205 0.041 0.0586
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0046 0.0145
Loa Loa (eye worm) TK protein kinase 0.0019 0.0004 0.0012
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0053 0.0077 0.0992
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.002 0.0057
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0019 0.0004 0.0012
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0033 0.0035 0.0307
Brugia malayi Immunoglobulin I-set domain containing protein 0.0021 0.0007 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.001 0.002
Schistosoma mansoni protein kinase 0.0019 0.0004 0.0004
Echinococcus granulosus tyrosine protein kinase pr2 0.0019 0.0004 0.0005
Brugia malayi beta-lactamase family protein 0.0114 0.0211 0.0706
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0022
Brugia malayi hypothetical protein 0.0037 0.0042 0.014
Loa Loa (eye worm) histone methyltransferase 0.0037 0.0043 0.0143
Mycobacterium ulcerans hypothetical protein 0.0053 0.0077 0.0992
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0019 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0227 0.0458 0.1529
Echinococcus granulosus dnaJ subfamily B 0.1706 0.369 0.5275
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0021 0.0008 0.0013
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0205 0.041 0.1358
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0098 0.0177 0.0591
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0021 0.0007 0.001
Echinococcus multilocularis insulin receptor 0.0019 0.0004 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0046 0.0145
Echinococcus granulosus snurportin 1 0.0308 0.0636 0.0909
Schistosoma mansoni tyrosine kinase 0.0019 0.0004 0.0004
Brugia malayi MH1 domain containing protein 0.0034 0.0036 0.0119
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0205 0.041 0.2598
Loa Loa (eye worm) TK/ROR protein kinase 0.004 0.0048 0.0162
Loa Loa (eye worm) TK/FER protein kinase 0.0019 0.0004 0.0012
Brugia malayi MH1 domain containing protein 0.0019 0.0003 0.0009
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0205 0.041 0.5722
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0205 0.041 0.2598
Trypanosoma cruzi hypothetical protein, conserved 0.0114 0.0211 0.0695
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0023 0.0012 0.004
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0108 0.0198 0.4364
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0038 0.0046 0.0142
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0043 0.0232
Loa Loa (eye worm) TK/CSK protein kinase 0.0019 0.0004 0.0012
Loa Loa (eye worm) hypothetical protein 0.004 0.005 0.0166
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.0008 0.0013
Echinococcus multilocularis titin 0.0021 0.0007 0.001
Schistosoma mansoni hypothetical protein 0.0158 0.0306 0.0306
Echinococcus granulosus low density lipoprotein receptor ldl 0.0019 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0015
Leishmania major DNA polymerase kappa, putative 0.0038 0.0046 0.0153
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0019 0.0004 0.0005
Brugia malayi Protein kinase domain containing protein 0.0019 0.0004 0.0012
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0019 0.0004 0.0005
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0019 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0311 0.0641 0.2141
Plasmodium falciparum glutathione reductase 0.0047 0.0065 0.0573
Loa Loa (eye worm) hypothetical protein 0.0187 0.037 0.1237
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0053 0.0077 0.0992
Leishmania major protein kinase, putative 0.0032 0.0032 0.0108
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0019 0.0004 0.0005
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.004 0.0049 0.0071
Schistosoma mansoni nephrin 0.0044 0.0057 0.0057
Echinococcus granulosus lamin dm0 0.0026 0.0019 0.0028
Brugia malayi Protein kinase domain containing protein 0.0019 0.0004 0.0012
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0019 0.0004 0.0005
Schistosoma mansoni protein kinase 0.0019 0.0004 0.0004
Brugia malayi Immunoglobulin I-set domain containing protein 0.0021 0.0007 0.0022
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0025 0.0219
Schistosoma mansoni tyrosine kinase 0.0019 0.0004 0.0004
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0039 0.0048 0.5
Loa Loa (eye worm) TK/ABL protein kinase 0.0019 0.0004 0.0012
Brugia malayi SRC-1 0.0019 0.0004 0.0012
Echinococcus granulosus importin subunit beta 1 0.0029 0.0025 0.0036
Echinococcus granulosus roundabout 2 0.0044 0.0057 0.0082
Echinococcus granulosus titin 0.0037 0.0043 0.0062
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0008 0.0011
Schistosoma mansoni hypothetical protein 0.0308 0.0636 0.0636
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.004 0.0048 0.0069
Brugia malayi Immunoglobulin I-set domain containing protein 0.1112 0.2393 0.7991
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0021 0.0059
Echinococcus multilocularis Smad4 0.0034 0.0036 0.0051
Entamoeba histolytica protein kinase, putative 0.0019 0.0004 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0021 0.0059
Onchocerca volvulus 0.0024 0.0014 0.0036
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0004 0.0015
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0205 0.041 0.5722
Toxoplasma gondii histone lysine methyltransferase SET1 0.0227 0.0458 0.4005
Schistosoma mansoni basigin related 0.0019 0.0004 0.0004
Echinococcus multilocularis transfer RNA-Thr 0.0019 0.0004 0.0005
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0042 0.006
Schistosoma mansoni tyrosine kinase 0.0019 0.0004 0.0004
Schistosoma mansoni microtubule-associated protein tau 0.0722 0.154 0.154
Trichomonas vaginalis ran, putative 0.0021 0.0008 0.0016
Brugia malayi Protein kinase domain containing protein 0.0019 0.0004 0.0012
Brugia malayi Raf kinase 0.0019 0.0004 0.0012
Echinococcus multilocularis insulin growth factor binding 0.0021 0.0007 0.001
Echinococcus granulosus contactin 0.0044 0.0057 0.0082
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0023 0.0012 0.0028
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0035 0.0117
Echinococcus granulosus microtubule associated protein 2 0.0722 0.154 0.2201
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0053 0.0077 0.0992
Echinococcus granulosus titin 0.0021 0.0007 0.001
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0065 0.0544
Echinococcus multilocularis protein tyrosine kinase 0.0019 0.0004 0.0005
Trypanosoma cruzi cytochrome P450, putative 0.0342 0.0711 0.2364
Trichomonas vaginalis CAMK family protein kinase 0.1387 0.2994 1
Schistosoma mansoni titin 0.0021 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.004 0.005 0.0167
Echinococcus granulosus insulin growth factor binding 0.0021 0.0007 0.001
Echinococcus multilocularis transfer RNA-Phe 0.0024 0.0014 0.0021
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0019 0.0004 0.0004
Echinococcus granulosus titin 0.0037 0.0043 0.0062
Loa Loa (eye worm) TK/FER protein kinase 0.0019 0.0004 0.0012
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.0032
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0019 0.0004 0.0005
Brugia malayi Immunoglobulin I-set domain containing protein 0.0024 0.0014 0.0048
Echinococcus granulosus tyrosine protein kinase Srms 0.0019 0.0004 0.0005
Mycobacterium ulcerans glutaminase 0.0302 0.0622 0.8738
Loa Loa (eye worm) hypothetical protein 0.0029 0.0025 0.0084
Schistosoma mansoni protein kinase 0.0019 0.0004 0.0004
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.004 0.005 0.005
Echinococcus multilocularis cpg binding protein 0.0127 0.0239 0.0341
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0053 0.0077 0.045
Trichomonas vaginalis AGC family protein kinase 0.054 0.1143 0.3811
Onchocerca volvulus 0.0114 0.0211 0.0695
Loa Loa (eye worm) hypothetical protein 0.0039 0.0048 0.0161
Brugia malayi Protein kinase domain containing protein 0.0019 0.0004 0.0012
Loa Loa (eye worm) protein kinase domain-containing protein 0.0019 0.0004 0.0012
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0044 0.0057 0.019
Loa Loa (eye worm) TK protein kinase 0.0136 0.026 0.0868
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0023 0.0012 0.0017
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0046 0.0145
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0019 0.0004 0.0012
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.1387 0.2994 1
Loa Loa (eye worm) hypothetical protein 0.0059 0.0091 0.0302
Echinococcus granulosus protein kinase 0.0019 0.0004 0.0005
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.3218 0.6996 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.004 0.0049 0.0165
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0019 0.0004 0.0012
Loa Loa (eye worm) hypothetical protein 0.0436 0.0915 0.3056
Loa Loa (eye worm) TK/FER protein kinase 0.0019 0.0004 0.0012
Echinococcus granulosus beta LACTamase domain containing family member 0.0114 0.0211 0.0302
Brugia malayi Protein kinase domain containing protein 0.0019 0.0004 0.0012
Brugia malayi Pax transcription factor protein 2 0.0247 0.0502 0.1678
Schistosoma mansoni tyrosine kinase 0.0019 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0227 0.0458 0.1529
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0043 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0021 0.0059
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0043 0.0061
Brugia malayi MH2 domain containing protein 0.0034 0.0036 0.0119
Echinococcus granulosus tyrosine protein kinase Src42A 0.0019 0.0004 0.0005
Mycobacterium tuberculosis Conserved protein 0.0114 0.0211 0.1317
Loa Loa (eye worm) hypothetical protein 0.0044 0.0057 0.019
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0037 0.0043 0.0145
Echinococcus multilocularis ephrin type A receptor 4 A 0.0019 0.0004 0.0005
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0019 0.0004 0.0005
Brugia malayi Immunoglobulin I-set domain containing protein 0.0021 0.0007 0.0022
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0205 0.041 0.2598
Loa Loa (eye worm) hypothetical protein 0.0187 0.037 0.1237
Echinococcus granulosus tyrosine kinase 0.0019 0.0004 0.0005
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.0012 0.0041
Schistosoma mansoni smad1 5 8 and 0.0034 0.0036 0.0036
Echinococcus multilocularis hemicentin 1 0.004 0.0049 0.0071
Trypanosoma brucei unspecified product 0.0027 0.002 0.0057
Schistosoma mansoni titin 0.0021 0.0007 0.0007
Brugia malayi Latrophilin receptor protein 2 0.0098 0.0177 0.0591
Loa Loa (eye worm) hypothetical protein 0.0098 0.0177 0.0591
Brugia malayi Receptor family ligand binding region containing protein 0.0019 0.0004 0.0012
Echinococcus granulosus geminin 0.0725 0.1548 0.2212
Schistosoma mansoni tyrosine kinase 0.0019 0.0004 0.0004
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0019 0.0004 0.0005
Echinococcus granulosus twitchin 0.0221 0.0444 0.0635
Brugia malayi hypothetical protein 0.0311 0.0641 0.2141
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0023 0.0011 0.0016
Loa Loa (eye worm) TK/DDR protein kinase 0.0019 0.0004 0.0012
Brugia malayi Protein kinase domain containing protein 0.0019 0.0004 0.0012
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0022
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0032 0.0032 0.0046
Loa Loa (eye worm) hypothetical protein 0.0772 0.1651 0.5512
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0021 0.0007 0.0007
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0019 0.0004 0.0005
Schistosoma mansoni cell adhesion molecule 0.0024 0.0014 0.0014
Brugia malayi Immunoglobulin I-set domain containing protein 0.0019 0.0004 0.0015
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0019 0.0004 0.0005
Loa Loa (eye worm) glutathione reductase 0.0047 0.0065 0.0219
Brugia malayi AMP-binding enzyme family protein 0.0053 0.0077 0.0258
Brugia malayi Furin-like cysteine rich region family protein 0.0019 0.0004 0.0012
Schistosoma mansoni tyrosine kinase 0.0019 0.0004 0.0004
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0019 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0053 0.0077 0.0258
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0019 0.0064
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0205 0.041 0.2598
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0022 0.001 0.0084
Loa Loa (eye worm) Smad1 0.0034 0.0036 0.0119
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0019 0.0004 0.0004
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0205 0.041 0.5722
Schistosoma mansoni cytochrome P450 0.0205 0.041 0.041
Loa Loa (eye worm) TK/FER protein kinase 0.0019 0.0004 0.0012
Echinococcus granulosus neuropeptide receptor A26 0.151 0.3264 0.4665
Brugia malayi Immunoglobulin domain containing protein 0.0019 0.0004 0.0015
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0053 0.0077 0.1144
Brugia malayi Immunoglobulin I-set domain containing protein 0.0024 0.0014 0.0048
Brugia malayi kettin 0.0021 0.0007 0.0022
Leishmania major importin beta-1 subunit, putative 0.0023 0.0013 0.0044
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0044 0.0057 0.0082
Echinococcus granulosus epidermal growth factor receptor 0.0019 0.0004 0.0005
Loa Loa (eye worm) projectin 0.0024 0.0014 0.0048
Schistosoma mansoni glutaminase 0.0302 0.0622 0.0622
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0021 0.0007 0.0022
Echinococcus granulosus intermediate filament protein 0.0026 0.0019 0.0028
Brugia malayi integrin-linked kinase 0.0019 0.0004 0.0012
Echinococcus multilocularis down syndrome cell adhesion 0.0021 0.0007 0.001
Entamoeba histolytica peptidase, C54 family 0.0023 0.0012 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.004 0.005 0.0156
Echinococcus granulosus retinal guanylyl cyclase 2 0.0019 0.0004 0.0005
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0038 0.0046 0.0248
Brugia malayi Immunoglobulin I-set domain containing protein 0.0044 0.0057 0.019
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.001 0.002
Echinococcus multilocularis aurora kinase A 0.054 0.1143 0.1634
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0019 0.0064
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0019 0.0004 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.1387 0.2994 0.2994
Echinococcus granulosus lamin 0.0026 0.0019 0.0028
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0053 0.0077 0.1144
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0098 0.0177 0.0253
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0008 0.0035
Schistosoma mansoni hypothetical protein 0.0019 0.0004 0.0004
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0032 0.0032 0.0283
Brugia malayi Immunoglobulin I-set domain containing protein 0.004 0.0049 0.0165
Brugia malayi Cytochrome P450 family protein 0.0804 0.172 0.5743
Echinococcus multilocularis titin 0.0021 0.0007 0.001
Echinococcus multilocularis twitchin 0.0034 0.0036 0.0051
Onchocerca volvulus 0.0026 0.0019 0.0053
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0065 0.0374
Brugia malayi Immunoglobulin I-set domain containing protein 0.0044 0.0057 0.019
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0012
Loa Loa (eye worm) AUR protein kinase 0.054 0.1143 0.3818
Loa Loa (eye worm) cytochrome P450 family protein 0.0342 0.0711 0.2373
Schistosoma mansoni tyrosine kinase 0.0116 0.0215 0.0215
Loa Loa (eye worm) pax transcription factor protein 2 0.0247 0.0502 0.1678
Echinococcus multilocularis snurportin 1 0.0308 0.0636 0.0909
Schistosoma mansoni Smad4 0.0034 0.0036 0.0036
Echinococcus multilocularis dna polymerase eta 0.0038 0.0046 0.0066
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0044 0.0057 0.0082
Echinococcus granulosus tyrosine protein kinase ABL1 0.0019 0.0004 0.0005
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.054 0.1143 0.3811
Brugia malayi Protein kinase domain containing protein 0.0019 0.0004 0.0012
Trypanosoma brucei cysteine peptidase, Clan CA, family C54, putative 0.0023 0.0012 0.0031
Echinococcus granulosus tyrosine protein kinase 0.0019 0.0004 0.0005
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.004 0.005 0.0167
Loa Loa (eye worm) MH2 domain-containing protein 0.0034 0.0036 0.0119
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0012
Echinococcus multilocularis tyrosine protein kinase csk 0.0019 0.0004 0.0005
Trypanosoma cruzi polo-like protein kinase, putative 0.1387 0.2994 1
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0033 0.0035 0.0277
Loa Loa (eye worm) RGC/RGC protein kinase 0.0019 0.0004 0.0012
Echinococcus multilocularis mothers against decapentaplegic 5 0.0034 0.0036 0.0051
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0205 0.041 0.1358
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0019 0.0004 0.0003
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0019 0.0004 0.0012
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0019 0.0004 0.0004
Schistosoma mansoni tyrosine kinase 0.0019 0.0004 0.0004
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0004 0.0004
Echinococcus multilocularis tyrosine protein kinase Abl 0.0019 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0012
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0046 0.0145
Entamoeba histolytica hypothetical protein 0.0023 0.0013 0.0032
Onchocerca volvulus 0.0021 0.0007 0.0011
Loa Loa (eye worm) TK/FER protein kinase 0.0019 0.0004 0.0012
Schistosoma mansoni nephrin related 0.0021 0.0007 0.0007
Mycobacterium ulcerans hypothetical protein 0.0114 0.0211 0.29
Onchocerca volvulus Putative titin 0.0021 0.0007 0.0011
Toxoplasma gondii protein kinase domain-containing protein 0.0019 0.0004 0.0031
Echinococcus granulosus activated cdc42 kinase 1 0.0019 0.0004 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0021 0.0059
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0019 0.0004 0.0004
Brugia malayi Prion-like- 0.004 0.0049 0.0165
Schistosoma mansoni protein kinase 0.0019 0.0004 0.0004
Echinococcus granulosus tyrosine protein kinase Src64B 0.0019 0.0004 0.0005
Toxoplasma gondii protein kinase 0.0019 0.0004 0.0031
Schistosoma mansoni tyrosine kinase 0.0019 0.0004 0.0004
Onchocerca volvulus 0.0024 0.0014 0.0036
Echinococcus granulosus serine:threonine protein kinase 12 B 0.054 0.1143 0.1634
Schistosoma mansoni survival motor neuron protein 0.0158 0.0306 0.0306
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0043 0.0131
Onchocerca volvulus 0.0026 0.0019 0.0053
Entamoeba histolytica hypothetical protein 0.0037 0.0042 0.0128
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0033 0.0035 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0021 0.0059
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0046 0.0145
Brugia malayi Heparan sulfate 0.0019 0.0004 0.0015
Brugia malayi MH2 domain containing protein 0.0494 0.1043 0.3483
Echinococcus granulosus tyrosine protein kinase shark 0.0019 0.0004 0.0005
Plasmodium vivax hypothetical protein, conserved 0.0114 0.0211 0.1824
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0032 0.0032 0.0099
Plasmodium falciparum serine/threonine protein kinase, putative 0.054 0.1143 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0022
Mycobacterium tuberculosis Probable esterase LipL 0.0114 0.0211 0.1317
Loa Loa (eye worm) TK/FER protein kinase 0.0019 0.0004 0.0012

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) = 83 % Inhibition of Pseudomonas aeruginosa OXA10 beta-lactamase assessed as residual activity at 100 uM at pH 5 using acetate buffer by spectrophotometry ChEMBL. 19467869
Inhibition (binding) = 93 % Inhibition of Enterobacter cloacae P99 beta-lactamase assessed as residual activity at 100 uM at pH 5 using acetate buffer by spectrophotometry ChEMBL. 19467869
Inhibition (binding) = 94 % Inhibition of Enterobacter cloacae NMCA beta-lactamase assessed as residual activity at 100 uM at pH 7 using phosphate buffer by spectrophotometry ChEMBL. 19467869
Inhibition (binding) = 96 % Inhibition of Bacillus licheniformis BS3 beta-lactamase assessed as residual activity at 100 uM at pH 7 using phosphate buffer by spectrophotometry ChEMBL. 19467869
Inhibition (binding) = 96 % Inhibition of Pseudomonas aeruginosa OXA10 beta-lactamase assessed as residual activity at 100 uM at pH 7 using phosphate buffer by spectrophotometry ChEMBL. 19467869
Inhibition (binding) = 96 % Inhibition of Enterobacter cloacae NMCA beta-lactamase assessed as residual activity at 100 uM at pH 5 using acetate buffer by spectrophotometry ChEMBL. 19467869
Inhibition (binding) = 97 % Inhibition of Bacillus licheniformis BS3 beta-lactamase assessed as residual activity at 100 uM at pH 5 using acetate buffer by spectrophotometry ChEMBL. 19467869
Inhibition (binding) = 100 % Inhibition of Enterobacter cloacae P99 beta-lactamase assessed as residual activity at 100 uM at pH 7 using phosphate buffer by spectrophotometry ChEMBL. 19467869
Inhibition (binding) = 100 % Inhibition of Pseudomonas aeruginosa VIM4 beta-lactamase assessed as residual activity at 100 uM at pH 7 using HEPES buffer by spectrophotometry ChEMBL. 19467869

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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