Detailed information for compound 1366383

Basic information

Technical information
  • TDR Targets ID: 1366383
  • Name: 3-methyl-2,5-di(phenyl)-1,3-oxazol-3-ium
  • MW: 236.288 | Formula: C16H14NO+
  • H donors: 0 H acceptors: 0 LogP: 3.79 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: C[n+]1cc(oc1c1ccccc1)c1ccccc1
  • InChi: 1S/C16H14NO/c1-17-12-15(13-8-4-2-5-9-13)18-16(17)14-10-6-3-7-11-14/h2-12H,1H3/q+1
  • InChiKey: PYHSOYNJMMGIHW-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-methyl-2,5-di(phenyl)oxazol-3-ium
  • ZINC03178347

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific methyltransferase 2A Starlite/ChEMBL No references
Schistosoma mansoni Thioredoxin glutathione reductase Starlite/ChEMBL No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum ko:K00384 thioredoxin reductase (NADPH) [EC1.8.1.9], putative Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma cruzi trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Neospora caninum MGC84926 protein, related Get druggable targets OG5_126785 All targets in OG5_126785
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K10771 AP endonuclease 1, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania mexicana apurinic/apyrimidinic endonuclease-redox protein,AP-endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Entamoeba histolytica exodeoxyribonuclease III, putative Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium knowlesi AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Toxoplasma gondii thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium vivax thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania braziliensis apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei gambiense trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium knowlesi thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Wolbachia endosymbiont of Brugia malayi exonuclease III Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans similar to S. cerevisiae GLR1 (YPL091W) glutathione oxidoreductase Get druggable targets OG5_126785 All targets in OG5_126785
Brugia malayi exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi Thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania braziliensis trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Cryptosporidium hominis dna-(apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K09188 myeloid/lymphoid or mixed-lineage leukemia protein 3, putative Get druggable targets OG5_130642 All targets in OG5_130642
Leishmania major trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium knowlesi glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Neospora caninum Glutathione reductase, related Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania donovani trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA Get druggable targets OG5_126768 All targets in OG5_126768
Theileria parva thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus multilocularis thioredoxin glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Brugia malayi glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania infantum trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Candida albicans similar to S. cerevisiae GLR1 (YPL091W) glutathione oxidoreductase Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma congolense trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Babesia bovis thiodoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Toxoplasma gondii histone lysine methyltransferase SET1 Get druggable targets OG5_130642 All targets in OG5_130642
Loa Loa (eye worm) exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium hominis thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) Get druggable targets OG5_126768 All targets in OG5_126768
Neospora caninum Multidomain chromatinic protein with the following architecture: 3x PHD-bromo-3xPHD-SET domain and associated cysteine cluster a Get druggable targets OG5_130642 All targets in OG5_130642
Echinococcus granulosus thioredoxin glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Neospora caninum hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Toxoplasma gondii exonuclease III APE Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K10772 AP endonuclease 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium berghei thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma mansoni mixed-lineage leukemia protein mll Get druggable targets OG5_130642 All targets in OG5_130642
Plasmodium yoelii thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium yoelii putative AP endonuclease-related Get druggable targets OG5_126768 All targets in OG5_126768
Giardia lamblia Endonuclease/Exonuclease/phosphatase Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium falciparum thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania major apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium parvum conserved hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania infantum apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium falciparum glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma brucei trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma congolense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Theileria parva hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei gambiense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium yoelii glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium berghei glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium berghei AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Treponema pallidum exodeoxyribonuclease (exoA) Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania mexicana trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium vivax glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania donovani apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium parvum thioredoxin reductase 1 Get druggable targets OG5_126785 All targets in OG5_126785
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr Get druggable targets OG5_126785 All targets in OG5_126785
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Neospora caninum hypothetical protein Thioredoxin glutathione reductase   598 aa 485 aa 30.5 %
Plasmodium yoelii dihydrolipoamide dehydrogenase Thioredoxin glutathione reductase   598 aa 537 aa 24.2 %
Neospora caninum glutathione reductase, putative Thioredoxin glutathione reductase   598 aa 532 aa 34.6 %
Plasmodium knowlesi dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin glutathione reductase   598 aa 518 aa 22.0 %
Neospora caninum Dihydrolipoyl dehydrogenase (EC 1.8.1.4), related Thioredoxin glutathione reductase   598 aa 512 aa 28.3 %
Onchocerca volvulus Thioredoxin glutathione reductase   598 aa 533 aa 50.8 %
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast Thioredoxin glutathione reductase   598 aa 513 aa 25.0 %
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin glutathione reductase   598 aa 521 aa 21.5 %
Plasmodium berghei dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin glutathione reductase   598 aa 538 aa 25.3 %
Toxoplasma gondii NADPH-glutathione reductase Thioredoxin glutathione reductase   598 aa 555 aa 33.5 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.1047 0.4309 0.522
Entamoeba histolytica hypothetical protein 0.0106 0.0012 0.0023
Entamoeba histolytica protein kinase, putative 0.0105 0.0009 0.0014
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0129 0.0118 0.0208
Schistosoma mansoni adapter molecule crk 0.0213 0.0501 0.0855
Schistosoma mansoni protein kinase 0.0179 0.0345 0.0586
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0179 0.0345 0.1464
Echinococcus multilocularis tyrosine protein kinase csk 0.0105 0.0009 0.0006
Schistosoma mansoni serine/threonine protein kinase 0.0486 0.1747 0.2997
Loa Loa (eye worm) TK protein kinase 0.0601 0.2271 0.2465
Entamoeba histolytica tyrosine kinase, putative 0.0105 0.0009 0.0014
Echinococcus multilocularis roundabout 2 0.0125 0.0101 0.0118
Trichomonas vaginalis AGC family protein kinase 0.012 0.0075 0.0275
Echinococcus multilocularis nervana 2 0.0249 0.0664 0.08
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0254 0.0688 0.2941
Brugia malayi Protein kinase domain containing protein 0.0234 0.0598 0.064
Trichomonas vaginalis CAMK family protein kinase 0.0284 0.0826 0.3401
Echinococcus multilocularis FL cytokine receptor 0.0105 0.0009 0.0006
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0326 0.1015 0.1012
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0452 0.1591 0.1726
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0105 0.0009 0.0006
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0105 0.0009 0.0005
Entamoeba histolytica tyrosine kinase, putative 0.0105 0.0009 0.0014
Trichomonas vaginalis CAMK family protein kinase 0.0608 0.2305 0.9564
Echinococcus multilocularis hypothetical protein 0.0229 0.0576 0.0694
Onchocerca volvulus 0.045 0.1582 0.3015
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0182 0.0359 0.1516
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0105 0.0009 0.001
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0122 0.0088 0.0095
Brugia malayi Protein kinase domain containing protein 0.0187 0.038 0.0404
Trichomonas vaginalis CAMK family protein kinase 0.0488 0.1757 0.7281
Brugia malayi Protein kinase domain containing protein 0.2121 0.9213 1
Brugia malayi Protein kinase domain containing protein 0.0345 0.1106 0.1192
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0254 0.0688 0.2829
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0249 0.0664 0.08
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0105 0.0009 0.0005
Echinococcus granulosus defective proboscis extension response 0.0188 0.0387 0.0383
Schistosoma mansoni vav2 0.0243 0.064 0.1093
Trichomonas vaginalis STE family protein kinase 0.0193 0.041 0.1672
Trichomonas vaginalis STE family protein kinase 0.0144 0.0187 0.0743
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0434 0.1509 0.1638
Brugia malayi Protein kinase domain containing protein 0.0234 0.0598 0.064
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0489 0.1764 0.1914
Schistosoma mansoni tyrosine kinase 0.0318 0.0982 0.1681
Giardia lamblia Kinase, PLK 0.0608 0.2305 1
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0608 0.2305 1
Brugia malayi SH2 domain containing protein 0.0234 0.0598 0.064
Echinococcus multilocularis expressed conserved protein 0.0302 0.091 0.1099
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.1351 0.5696 0.6183
Echinococcus granulosus insulin receptor 0.1012 0.4148 0.4146
Echinococcus granulosus protein kinase c iota type 0.0643 0.2466 0.2463
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0445 0.1817
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.014 0.0167 0.0658
Loa Loa (eye worm) hypothetical protein 0.0675 0.261 0.2833
Schistosoma mansoni serine/threonine protein kinase 0.0552 0.2048 0.3515
Loa Loa (eye worm) hypothetical protein 0.0105 0.0009 0.001
Echinococcus multilocularis titin 0.0158 0.0249 0.0297
Schistosoma mansoni serine/threonine protein kinase 0.0486 0.1747 0.2997
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0201 0.0445 0.0535
Onchocerca volvulus 0.0436 0.152 0.2895
Loa Loa (eye worm) TK/FER protein kinase 0.0234 0.0598 0.0649
Schistosoma mansoni tyrosine kinase 0.0105 0.0009 0.0008
Schistosoma mansoni serine/threonine protein kinase 0.0129 0.0118 0.0195
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0825 0.3298 0.3579
Loa Loa (eye worm) SH2 domain-containing protein 0.0129 0.0118 0.0128
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0919 0.3725 0.4512
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0793 0.3152 0.3415
Echinococcus granulosus serine:threonine protein kinase N2 0.0654 0.2517 0.2514
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0244 0.0643 0.0698
Giardia lamblia Kinase, CMGC SRPK 0.0187 0.038 0.1618
Echinococcus granulosus growth factor receptor bound protein 2 0.0217 0.0522 0.0518
Loa Loa (eye worm) AUR protein kinase 0.0327 0.1022 0.1109
Loa Loa (eye worm) hypothetical protein 0.0114 0.0051 0.0055
Echinococcus multilocularis cyclin dependent kinase 1 0.0267 0.0748 0.0902
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0225 0.0555 0.4981
Entamoeba histolytica PH domain containing protein kinase, putative 0.0342 0.1092 0.3168
Echinococcus granulosus tyrosine kinase 0.0432 0.1503 0.1499
Schistosoma mansoni serine/threonine protein kinase 0.0267 0.0748 0.1279
Loa Loa (eye worm) CAMK protein kinase 0.0158 0.0249 0.027
Trichomonas vaginalis AGC family protein kinase 0.0428 0.1485 0.6149
Schistosoma mansoni serine/threonine-protein kinase 0.0343 0.1095 0.1875
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0105 0.0009 0.0014
Loa Loa (eye worm) TK/ALK protein kinase 0.0363 0.1187 0.1288
Schistosoma mansoni tyrosine kinase 0.0804 0.3199 0.5493
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0254 0.0688 0.0684
Brugia malayi Protein kinase domain containing protein 0.0369 0.1213 0.1309
Brugia malayi Protein kinase domain containing protein 0.034 0.1081 0.1165
Entamoeba histolytica protein kinase domain containing protein 0.0105 0.0009 0.0014
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0793 0.3152 0.3817
Loa Loa (eye worm) hypothetical protein 0.0252 0.0678 0.0736
Loa Loa (eye worm) hypothetical protein 0.1039 0.4274 0.4639
Loa Loa (eye worm) hypothetical protein 0.0322 0.0998 0.1083
Giardia lamblia Kinase, CMGC CDK 0.0267 0.0748 0.3217
Brugia malayi Temporarily assigned gene name protein 59 0.0252 0.0678 0.0727
Echinococcus multilocularis cyclin dependent kinase 0.0267 0.0748 0.0902
Trichomonas vaginalis CMGC family protein kinase 0.0312 0.0955 0.394
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0122 0.0088 0.0086
Echinococcus multilocularis heat shock protein 70 0.0105 0.0009 0.0006
Echinococcus multilocularis protein KINase family member (kin 25) 0.0105 0.0009 0.0006
Echinococcus multilocularis SH2 motif 0.0129 0.0118 0.0138
Onchocerca volvulus 0.0234 0.0598 0.1129
Trichomonas vaginalis CMGC family protein kinase 0.0289 0.0849 0.3499
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0825 0.3298 0.3994
Trichomonas vaginalis AGC family protein kinase 0.012 0.0075 0.0275
Giardia lamblia Kinase, CMGC CLK 0.0345 0.1106 0.4777
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0456 0.161 0.1606
Loa Loa (eye worm) hypothetical protein 0.0119 0.0074 0.0081
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0486 0.1747 0.1744
Echinococcus multilocularis nervana 2 0.0249 0.0664 0.08
Echinococcus granulosus epidermal growth factor receptor 0.1378 0.582 0.5818
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0322 0.1 0.0996
Schistosoma mansoni serine/threonine protein kinase 0.0254 0.0688 0.1176
Schistosoma mansoni tyrosine kinase 0.0572 0.2142 0.3676
Onchocerca volvulus 0.0158 0.0249 0.046
Trichomonas vaginalis STE family protein kinase 0.019 0.0396 0.1614
Schistosoma mansoni protein kinase 0.0105 0.0009 0.0008
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0345 0.1106 0.4777
Brugia malayi casein kinase 1, delta 0.0244 0.0643 0.0689
Plasmodium falciparum serine/threonine protein kinase KIN 0.0201 0.0445 0.3977
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0456 0.161 0.1739
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0201 0.0445 0.19
Schistosoma mansoni protein tyrosine kinase 0.0105 0.0009 0.0008
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0302 0.091 0.1099
Schistosoma mansoni vesicular amine transporter 0.0188 0.0387 0.0658
Brugia malayi Protein kinase domain containing protein 0.101 0.4139 0.4487
Plasmodium vivax calcium-dependent protein kinase, putative 0.0226 0.0563 0.505
Echinococcus granulosus dual specificity 0.0275 0.0783 0.0779
Entamoeba histolytica protein kinase, putative 0.0105 0.0009 0.0014
Echinococcus granulosus cyclin dependent kinase 1 0.0267 0.0748 0.0744
Plasmodium vivax serine/threonine-protein kinase NEK4, putative 0.0114 0.0047 0.035
Schistosoma mansoni tyrosine kinase 0.0586 0.2205 0.3784
Schistosoma mansoni tyrosine kinase 0.0105 0.0009 0.0008
Entamoeba histolytica tyrosine kinase, putative 0.0105 0.0009 0.0014
Onchocerca volvulus 0.0162 0.0269 0.0498
Trypanosoma brucei protein kinase, putative 0.0289 0.0849 0.3499
Trichomonas vaginalis AGC family protein kinase 0.0631 0.241 1
Entamoeba histolytica protein kinase domain containing protein 0.0105 0.0009 0.0014
Echinococcus multilocularis 0.0391 0.1315 0.1589
Schistosoma mansoni tyrosine kinase 0.0105 0.0009 0.0008
Echinococcus multilocularis roundabout 2 0.0125 0.0101 0.0118
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0188 0.0387 0.0658
Schistosoma mansoni shc transforming protein 0.0129 0.0118 0.0195
Schistosoma mansoni protein kinase 0.0105 0.0009 0.0008
Brugia malayi serine/threonine protein kinase 6 0.0327 0.1022 0.1101
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0275 0.0783 0.337
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0369 0.1213 0.1466
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0129 0.0118 0.0473
Echinococcus multilocularis protein kinase c epsilon type 0.0459 0.1626 0.1967
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0201 0.0445 0.0483
Schistosoma mansoni protein kinase 0.0529 0.1944 0.3336
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0327 0.1022 0.9235
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0183 0.0364 0.0395
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0552 0.2048 0.2478
Entamoeba histolytica tyrosin kinase, putative 0.0105 0.0009 0.0014
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0129 0.0118 0.0138
Brugia malayi Protein kinase domain containing protein 0.0267 0.0748 0.0803
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0183 0.0364 0.0436
Schistosoma mansoni serine/threonine protein kinase 0.0303 0.0913 0.1562
Onchocerca volvulus 0.045 0.1582 0.3015
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0254 0.0688 0.2958
Entamoeba histolytica protein kinase, putative 0.0229 0.0576 0.1666
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0254 0.0688 0.2829
Trichomonas vaginalis AGC family protein kinase 0.014 0.0167 0.0658
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0552 0.2048 0.2045
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0289 0.0849 0.3658
Giardia lamblia Kinase, CK1 Casein kinase 0.0244 0.0643 0.2762
Entamoeba histolytica protein kinase, putative 0.0105 0.0009 0.0014
Entamoeba histolytica protein kinase, putative 0.0289 0.0849 0.2461
Brugia malayi STE20-like kinase MST 0.0578 0.2167 0.2345
Toxoplasma gondii AGC kinase 0.0611 0.2318 1
Plasmodium vivax casein kinase 1, putative 0.0244 0.0643 0.5783
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0701 0.2731 0.3307
Entamoeba histolytica hypothetical protein 0.0105 0.0009 0.0014
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0345 0.1106 0.4568
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0289 0.0849 0.0845
Trypanosoma brucei cdc2-related kinase 3 0.0267 0.0748 0.3076
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0917 0.3718 0.3716
Loa Loa (eye worm) hypothetical protein 0.0522 0.1914 0.2077
Trichomonas vaginalis CMGC family protein kinase 0.0225 0.0555 0.2276
Echinococcus granulosus serine:threonine protein kinase N2 0.0292 0.0862 0.0858
Trichomonas vaginalis CMGC family protein kinase 0.0225 0.0555 0.2276
Trypanosoma cruzi NIMA-related kinase, putative 0.0114 0.0047 0.0167
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0105 0.0009 0.0014
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0129 0.0118 0.0118
Entamoeba histolytica protein kinase domain containing protein 0.0112 0.0042 0.011
Schistosoma mansoni serine/threonine kinase 0.0362 0.1183 0.2027
Plasmodium falciparum NIMA related kinase 4 0.0114 0.0047 0.035
Echinococcus multilocularis tyrosine protein kinase 0.0645 0.2475 0.2996
Trichomonas vaginalis AGC family protein kinase 0.0327 0.1022 0.4219
Entamoeba histolytica protein kinase, putative 0.0203 0.0454 0.131
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0129 0.0118 0.0473
Schistosoma mansoni serine/threonine protein kinase 0.0201 0.0445 0.0759
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0445 0.1817
Echinococcus multilocularis death associated protein kinase 1 0.191 0.8251 1
Loa Loa (eye worm) hypothetical protein 0.0313 0.0956 0.1038
Plasmodium falciparum calcium-dependent protein kinase 1 0.0226 0.0563 0.505
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0445 0.1817
Echinococcus granulosus NCK adaptor protein 0.0213 0.0501 0.0497
Trichomonas vaginalis CMGC family protein kinase 0.0225 0.0555 0.2276
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0129 0.0118 0.0128
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0254 0.0688 0.083
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0486 0.1747 0.2114
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0516 0.1886 0.1883
Echinococcus granulosus mitogen activated protein kinase 3 0.0129 0.0118 0.0114
Brugia malayi Immunoglobulin I-set domain containing protein 0.0601 0.2271 0.2458
Echinococcus multilocularis tyrosine protein kinase csk 0.0105 0.0009 0.0006
Echinococcus multilocularis growth factor receptor bound protein 2 0.0213 0.0501 0.0603
Echinococcus multilocularis myosin iiia 0.019 0.0396 0.0476
Schistosoma mansoni hypothetical protein 0.0252 0.0678 0.1159
Brugia malayi SH2 domain containing protein 0.0129 0.0118 0.0118
Echinococcus multilocularis dual specificity 0.0312 0.0955 0.1153
Schistosoma mansoni protein kinase 0.0244 0.0643 0.1099
Loa Loa (eye worm) hypothetical protein 0.054 0.1994 0.2165
Echinococcus granulosus protein kinase c epsilon type 0.0459 0.1626 0.1623
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0445 0.1817
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0342 0.1092 0.4715
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0244 0.0643 0.0698
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.019 0.0396 0.1687
Entamoeba histolytica protein kinase domain containing protein 0.0225 0.0555 0.1606
Entamoeba histolytica protein kinase, putative 0.0105 0.0009 0.0014
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.018 0.0352 0.0422
Echinococcus granulosus cGMP dependent protein kinase 0.0302 0.091 0.0906
Trypanosoma brucei cdc2-related kinase 1 0.0267 0.0748 0.3076
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0105 0.0009 0.001
Trichomonas vaginalis CMGC family protein kinase 0.0267 0.0748 0.3076
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0254 0.0688 0.2958
Trichomonas vaginalis AGC family protein kinase 0.014 0.0167 0.0658
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0105 0.0009 0.0014
Echinococcus granulosus tyrosine protein kinase Fyn 0.0516 0.1886 0.1883
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0254 0.0688 0.6192
Schistosoma mansoni ephrin receptor 0.0249 0.0667 0.1141
Echinococcus granulosus activated cdc42 kinase 1 0.0105 0.0009 0.0005
Onchocerca volvulus Tyrosine kinase homolog 0.1248 0.5228 1
Plasmodium vivax protein kinase Crk2 0.0267 0.0748 0.6734
Loa Loa (eye worm) TK/DDR protein kinase 0.0105 0.0009 0.001
Giardia lamblia Kinase, CMGC CK2 0.0225 0.0555 0.2379
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0193 0.041 0.0493
Loa Loa (eye worm) AGC/PKG protein kinase 0.0302 0.091 0.0988
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0312 0.0955 0.394
Trichomonas vaginalis CMGC family protein kinase 0.0312 0.0955 0.394
Echinococcus multilocularis dual specificity protein kinase clk2 0.0345 0.1106 0.1336
Loa Loa (eye worm) hypothetical protein 0.0105 0.0009 0.001
Trypanosoma cruzi casein kinase II, putative 0.0225 0.0555 0.2379
Trichomonas vaginalis AGC family protein kinase 0.012 0.0075 0.0275
Echinococcus multilocularis cyclin dependent kinase 5 0.0267 0.0748 0.0902
Schistosoma mansoni serine/threonine protein kinase 0.0654 0.2517 0.432
Echinococcus granulosus tyrosine protein kinase Src42A 0.0332 0.1043 0.1039
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0345 0.1106 0.4777
Brugia malayi Fes/CIP4 homology domain containing protein 0.0255 0.0693 0.0743
Brugia malayi Protein kinase domain containing protein 0.0256 0.0699 0.075
Echinococcus multilocularis serine:threonine protein kinase N2 0.0362 0.1183 0.143
Echinococcus granulosus protein kinase shaggy 0.0289 0.0849 0.0845
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0302 0.091 0.1099
Trichomonas vaginalis STE family protein kinase 0.0193 0.041 0.1672
Echinococcus multilocularis casein kinase I delta 0.0244 0.0643 0.0775
Echinococcus granulosus casein kinase i 0.0244 0.0643 0.0639
Giardia lamblia Kinase, NEK 0.0306 0.0926 0.3993
Trypanosoma brucei aurora B kinase 0.0327 0.1022 0.4219
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0129 0.0118 0.0138
Schistosoma mansoni signal transduction protein lnk-related 0.0129 0.0118 0.0195
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0152 0.0223 0.0242
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0105 0.0009 0.0014
Brugia malayi Protein kinase domain containing protein 0.0436 0.1518 0.164
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0432 0.1503 0.1499
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0362 0.1183 0.143
Plasmodium falciparum protein kinase, putative 0.0179 0.0345 0.3064
Leishmania major casein kinase, putative 0.0244 0.0643 0.2762
Entamoeba histolytica protein kinase, putative 0.0105 0.0009 0.0014
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0193 0.041 0.0407
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0154 0.0232 0.0277
Giardia lamblia Kinase, STE STE20 0.019 0.0396 0.1687
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0223 0.0548 0.0595
Brugia malayi Immunoglobulin I-set domain containing protein 0.0113 0.0046 0.004
Onchocerca volvulus 0.0234 0.0598 0.1129
Echinococcus multilocularis Immunoglobulin 0.0188 0.0387 0.0464
Echinococcus granulosus serine:threonine protein kinase 3 0.0578 0.2167 0.2164
Schistosoma mansoni nck2/grb4 0.0213 0.0501 0.0855
Trichomonas vaginalis AGC family protein kinase 0.012 0.0075 0.0275
Leishmania major protein kinase, putative 0.019 0.0396 0.1687
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0105 0.0009 0.0005
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0105 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0268 0.0752 0.0816
Echinococcus multilocularis protein kinase 0.0105 0.0009 0.0006
Schistosoma mansoni serine/threonine protein kinase 0.0254 0.0688 0.1176
Echinococcus granulosus netrin receptor unc 5 0.0106 0.0014 0.001
Loa Loa (eye worm) TK/FER protein kinase 0.0234 0.0598 0.0649
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0183 0.0364 0.0395
Onchocerca volvulus 0.0289 0.0849 0.161
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0275 0.0783 0.3223
Trichomonas vaginalis CMGC family protein kinase 0.0312 0.0955 0.394
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0129 0.0118 0.0195
Trypanosoma cruzi casein kinase, delta isoform, putative 0.017 0.0307 0.1299
Entamoeba histolytica ankyrin repeat protein 0.0105 0.0009 0.0014
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0322 0.1 0.1207
Brugia malayi Doublecortin family protein 0.0339 0.1077 0.116
Plasmodium vivax serine/threonine kinase-1, putative 0.0345 0.1106 1
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0199 0.0437 0.0475
Entamoeba histolytica serine/threonine kinase, putative 0.0105 0.0009 0.0014
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0201 0.0445 0.19
Schistosoma mansoni protein kinase 0.0105 0.0009 0.0008
Echinococcus granulosus myotubularin protein 13 0.0114 0.0051 0.0047
Loa Loa (eye worm) hypothetical protein 0.0223 0.0548 0.0594
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0201 0.0445 0.19
Schistosoma mansoni protein kinase 0.0344 0.1101 0.1886
Schistosoma mansoni serine/threonine protein kinase 0.0122 0.0088 0.0144
Trichomonas vaginalis CMGC family protein kinase 0.0312 0.0955 0.394
Echinococcus granulosus tyrosine protein kinase shark 0.0715 0.2794 0.2791
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0451 0.159 0.1587
Trypanosoma cruzi polo-like protein kinase, putative 0.0608 0.2305 1
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0977 0.3988 0.4831
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0259 0.0709 0.0855
Trichomonas vaginalis AGC family protein kinase 0.0631 0.241 1
Loa Loa (eye worm) hypothetical protein 0.0105 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0129 0.0118 0.0128
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0226 0.0563 0.2399
Entamoeba histolytica protein kinase, putative 0.0105 0.0009 0.0014
Trichomonas vaginalis CAMK family protein kinase 0.0608 0.2305 0.9564
Entamoeba histolytica serine/threonine protein kinase, putative 0.0608 0.2305 0.6703
Schistosoma mansoni serine/threonine protein kinase 0.0303 0.0913 0.1562
Onchocerca volvulus 0.0234 0.0598 0.1129
Echinococcus granulosus retinal guanylyl cyclase 2 0.0105 0.0009 0.0005
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0047 0.016
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0445 0.1817
Plasmodium falciparum cGMP-dependent protein kinase 0.0302 0.091 0.8214
Echinococcus multilocularis netrin receptor unc 5 0.0106 0.0014 0.0012
Brugia malayi Tyrosine-protein kinase abl-1 0.0289 0.0846 0.091
Echinococcus granulosus serine threonine protein kinase nrc 0.0322 0.1 0.0996
Toxoplasma gondii aurora kinase 0.0327 0.1022 0.4387
Schistosoma mansoni titin 0.0158 0.0249 0.0421
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0312 0.0955 0.1028
Loa Loa (eye worm) SRC-1 0.0516 0.1886 0.2047
Brugia malayi protein-tyrosine kinase 0.0432 0.1503 0.1623
Echinococcus granulosus tyrosine protein kinase Lyn 0.059 0.2222 0.2219
Echinococcus granulosus integrin linked protein kinase 0.0105 0.0009 0.0005
Loa Loa (eye worm) TK protein kinase 0.0105 0.0009 0.001
Echinococcus granulosus fibroblast growth factor receptor 4 0.0552 0.2048 0.2045
Brugia malayi Protein kinase domain 0.0193 0.041 0.0436
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0267 0.0748 0.3217
Trichomonas vaginalis AGC family protein kinase 0.014 0.0167 0.0658
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0105 0.0009 0.0014
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0362 0.1183 0.143
Echinococcus multilocularis kinase suppressor of Ras 1 0.0105 0.0009 0.0006
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0516 0.1886 0.2282
Trichomonas vaginalis AGC family protein kinase 0.012 0.0075 0.0275
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.075 0.2954 0.32
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0887 0.358 0.3577
Entamoeba histolytica protein kinase domain containing protein 0.0105 0.0009 0.0014
Schistosoma mansoni tyrosine kinase 0.0105 0.0009 0.0008
Plasmodium vivax tyrosine kinase-like protein, putative 0.0182 0.0359 0.3191
Brugia malayi SH2 domain containing protein 0.0129 0.0118 0.0118
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0254 0.0688 0.0684
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0318 0.0982 0.1681
Echinococcus multilocularis Immunoglobulin 0.0188 0.0387 0.0464
Brugia malayi probable protein kinase 0.0596 0.225 0.2435
Entamoeba histolytica serine/threonine kinase, putative 0.0105 0.0009 0.0014
Schistosoma mansoni tyrosine kinase 0.0318 0.0982 0.1681
Entamoeba histolytica protein kinase domain containing protein 0.0105 0.0009 0.0014
Loa Loa (eye worm) SH2 domain-containing protein 0.0129 0.0118 0.0128
Plasmodium falciparum glycogen synthase kinase 3 0.0289 0.0849 0.7659
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0327 0.1022 0.2965
Entamoeba histolytica tyrosine kinase, putative 0.0105 0.0009 0.0014
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0129 0.0118 0.0114
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0289 0.0849 0.0922
Echinococcus granulosus tyrosine protein kinase csk 0.0105 0.0009 0.0005
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.019 0.0396 0.1614
Entamoeba histolytica p21-activated kinase 0.0213 0.0502 0.1451
Trichomonas vaginalis AGC family protein kinase 0.012 0.0075 0.0275
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0105 0.0009 0.0006
Entamoeba histolytica hypothetical protein 0.0105 0.0009 0.0014
Echinococcus granulosus rho-associated protein kinase 1 0.0732 0.287 0.2867
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0793 0.3152 0.3421
Loa Loa (eye worm) thyroid receptor interactor 0.0255 0.0693 0.0752
Echinococcus multilocularis raf serine:threonine protein kinase 0.0199 0.0439 0.0528
Entamoeba histolytica tyrosin kinase, putative 0.0105 0.0009 0.0014
Trichomonas vaginalis AGC family protein kinase 0.0327 0.1022 0.4219
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0445 0.1817
Echinococcus granulosus serine:threonine kinase SAD 1 0.0201 0.0445 0.0441
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0213 0.0501 0.0544
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0193 0.041 0.0493
Echinococcus granulosus casein kinase I delta 0.0244 0.0643 0.0639
Loa Loa (eye worm) hypothetical protein 0.0105 0.0009 0.001
Entamoeba histolytica serine/threonine kinase, putative 0.0105 0.0009 0.0014
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0529 0.1943 0.1939
Echinococcus granulosus expressed conserved protein 0.0129 0.0118 0.0114
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0516 0.1886 0.2282
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0327 0.1022 0.1234
Trichomonas vaginalis conserved hypothetical protein 0.0119 0.0074 0.0272
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0229 0.0575 0.0571
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0125 0.0101 0.0118
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0529 0.1944 0.2353
Loa Loa (eye worm) hypothetical protein 0.0407 0.1386 0.1504
Brugia malayi hypothetical protein 0.0129 0.0118 0.0118
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0159 0.0254 0.0304
Schistosoma mansoni tensin 0.0129 0.0118 0.0195
Trichomonas vaginalis AGC family protein kinase 0.012 0.0075 0.0275
Echinococcus granulosus expressed protein 0.0187 0.038 0.0377
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0105 0.0009 0.0005
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0345 0.1106 0.475
Trichomonas vaginalis AGC family protein kinase 0.014 0.0167 0.0658
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0289 0.0849 0.3638
Schistosoma mansoni neuroglian 0.0125 0.0101 0.0167
Brugia malayi Immunoglobulin I-set domain containing protein 0.0158 0.0249 0.0261
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0105 0.0009 0.001
Trichomonas vaginalis AGC family protein kinase 0.012 0.0075 0.0275
Loa Loa (eye worm) TK/ACK protein kinase 0.0105 0.0009 0.001
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0254 0.0688 0.0738
Echinococcus multilocularis epidermal growth factor receptor 0.0909 0.3679 0.4456
Schistosoma mansoni protein kinase 0.0144 0.0187 0.0315
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0516 0.1886 0.2282
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0129 0.0118 0.0114
Loa Loa (eye worm) TK/ABL protein kinase 0.0701 0.2731 0.2964
Echinococcus granulosus serine:threonine protein kinase TAO1 0.05 0.1811 0.1808
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0418 0.1437 0.1551
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0129 0.0118 0.0114
Echinococcus multilocularis mitogen activated protein kinase 0.0129 0.0118 0.0138
Trichomonas vaginalis AGC family protein kinase 0.014 0.0167 0.0658
Schistosoma mansoni tensin 0.0129 0.0118 0.0195
Loa Loa (eye worm) hypothetical protein 0.0229 0.0575 0.0624
Brugia malayi protein unc-22 0.0158 0.0249 0.0261
Echinococcus multilocularis tyrosine protein kinase csk 0.0105 0.0009 0.0006
Echinococcus multilocularis serine:threonine protein kinase N2 0.0654 0.2517 0.3047
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0459 0.1626 0.1765
Entamoeba histolytica protein kinase, putative 0.0105 0.0009 0.0014
Schistosoma mansoni serine/threonine protein kinase 0.0201 0.0445 0.0759
Brugia malayi Variant SH3 domain containing protein 0.0152 0.0223 0.0232
Schistosoma mansoni protein kinase 0.0225 0.0555 0.0948
Echinococcus multilocularis casein kinase I gamma 0.034 0.1081 0.1306
Brugia malayi Protein kinase domain containing protein 0.0488 0.1757 0.1899
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0125 0.0101 0.0167
Echinococcus granulosus calcium activated potassium channel 0.0303 0.0913 0.0909
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0129 0.0118 0.0473
Echinococcus granulosus suppressor of cytokine signaling 6 0.0129 0.0118 0.0114
Brugia malayi Protein kinase domain containing protein 0.1012 0.4148 0.4497
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0529 0.1943 0.2351
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0158 0.0249 0.027
Schistosoma mansoni protein kinase 0.0193 0.041 0.0699
Entamoeba histolytica protein kinase, putative 0.0362 0.1183 0.3434
Echinococcus granulosus SH2 domain containing adapter protein F 0.0129 0.0118 0.0114
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0166 0.0286 0.031
Trichomonas vaginalis AGC family protein kinase 0.014 0.0167 0.0658
Entamoeba histolytica PH domain containing protein kinase, putative 0.0274 0.078 0.226
Schistosoma mansoni serine/threonine protein kinase 0.0244 0.0643 0.1099
Entamoeba histolytica tyrosine kinase, putative 0.0105 0.0009 0.0014
Entamoeba histolytica hypothetical protein 0.0106 0.0012 0.0023
Brugia malayi Protein kinase domain containing protein 0.045 0.1582 0.171
Trichomonas vaginalis AGC family protein kinase 0.014 0.0167 0.0658
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.018 0.0352 0.0348
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0129 0.0118 0.0473
Loa Loa (eye worm) TK protein kinase 0.0645 0.2475 0.2686
Brugia malayi cytokine inducible SH2-containing protein 5 0.0129 0.0118 0.0118
Echinococcus multilocularis dual specificity 0.0312 0.0955 0.1153
Echinococcus multilocularis dual specificity 0.0312 0.0955 0.1153
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0263 0.073 0.0783
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0267 0.0748 0.0811
Trichomonas vaginalis CMGC family protein kinase 0.0345 0.1106 0.4568
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0762 0.3008 0.3265
Trichomonas vaginalis TKL family protein kinase 0.0107 0.0015 0.0026
Brugia malayi Immunoglobulin I-set domain containing protein 0.0223 0.0548 0.0585
Trichomonas vaginalis AGC family protein kinase 0.014 0.0167 0.0658
Entamoeba histolytica receptor protein kinase, putative 0.0105 0.0009 0.0014
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0552 0.2048 0.2223
Echinococcus granulosus nervana 2 0.0249 0.0664 0.066
Trichomonas vaginalis CMGC family protein kinase 0.0267 0.0748 0.3076
Trypanosoma cruzi casein kinase, putative 0.0244 0.0643 0.2762
Entamoeba histolytica serine/threonine protein kinase, putative 0.0114 0.0047 0.0126
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0362 0.1183 0.118
Entamoeba histolytica protein kinase, putative 0.0105 0.0009 0.0014
Brugia malayi ephrin receptor 1 precursor 0.0173 0.0319 0.0337
Brugia malayi Serine/threonine-protein kinase SULU 0.05 0.1811 0.1958
Loa Loa (eye worm) hypothetical protein 0.0313 0.0956 0.1038
Brugia malayi SRC-1 0.0516 0.1886 0.2039
Entamoeba histolytica tyrosine kinase, putative 0.0105 0.0009 0.0014
Trichomonas vaginalis CMGC family protein kinase 0.0267 0.0748 0.3076
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0887 0.358 0.4336
Echinococcus granulosus tyrosine protein kinase csk 0.0105 0.0009 0.0005
Trypanosoma cruzi cdc2-related kinase 1 0.0267 0.0748 0.3217
Trichomonas vaginalis CAMK family protein kinase 0.0608 0.2305 0.9564
Onchocerca volvulus 0.0416 0.1428 0.2719
Brugia malayi SH2 domain containing protein 0.0129 0.0118 0.0118
Schistosoma mansoni netrin receptor unc5 0.0106 0.0014 0.0017
Trichomonas vaginalis CMGC family protein kinase 0.0129 0.0118 0.0452
Schistosoma mansoni serine/threonine protein kinase 0.0159 0.0254 0.043
Entamoeba histolytica casein kinase, putative 0.0225 0.0555 0.1606
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0252 0.0678 0.1159
Schistosoma mansoni serine/threonine protein kinase 0.0529 0.1943 0.3333
Entamoeba histolytica protein kinase, putative 0.0144 0.0187 0.0534
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0254 0.0688 0.6192
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0129 0.0118 0.0138
Schistosoma mansoni serine/threonine protein kinase 0.0459 0.1626 0.2789
Entamoeba histolytica tyrosine kinase, putative 0.0105 0.0009 0.0014
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0451 0.159 0.1923
Echinococcus granulosus tyrosine protein kinase Srms 0.1152 0.4791 0.4789
Schistosoma mansoni serine/threonine protein kinase 0.0275 0.0783 0.1339
Trichomonas vaginalis CMGC family protein kinase 0.0129 0.0118 0.0452
Schistosoma mansoni serine/threonine protein kinase 0.0732 0.287 0.4927
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0105 0.0009 0.0014
Schistosoma mansoni tyrosine kinase 0.0839 0.3362 0.5774
Onchocerca volvulus 0.0658 0.2533 0.4837
Schistosoma mansoni serine/threonine protein kinase 0.0549 0.2034 0.349
Toxoplasma gondii NEK kinase 0.0114 0.0047 0.0166
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0917 0.3718 0.4504
Schistosoma mansoni serine/threonine protein kinase 0.05 0.1811 0.3107
Echinococcus multilocularis insulin receptor 0.1012 0.4148 0.5025
Entamoeba histolytica protein kinase domain containing protein 0.0105 0.0009 0.0014
Schistosoma mansoni ephrin receptor 0.014 0.017 0.0285
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0395 0.1334 0.1448
Loa Loa (eye worm) TK/EGFR protein kinase 0.1378 0.582 0.6317
Echinococcus granulosus dual specificity 0.0312 0.0955 0.0951
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.011 0.003 0.0025
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0275 0.0783 0.337
Entamoeba histolytica protein kinase 2, putative 0.0322 0.1 0.29
Loa Loa (eye worm) hypothetical protein 0.0105 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0278 0.0798 0.0866
Schistosoma mansoni protein kinase 0.0825 0.3298 0.5663
Entamoeba histolytica cysteine surface protein, putative 0.0105 0.0009 0.0014
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0105 0.0009 0.0014
Loa Loa (eye worm) hypothetical protein 0.0188 0.0387 0.042
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0105 0.0009 0.0005
Entamoeba histolytica serine/threonine kinase, putative 0.0105 0.0009 0.0014
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.05 0.1811 0.1966
Trichomonas vaginalis AGC family protein kinase 0.0183 0.0364 0.1477
Trichomonas vaginalis STE family protein kinase 0.0193 0.041 0.1672
Plasmodium vivax serine/threonine-protein kinase Nek1, putative 0.0114 0.0047 0.035
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0105 0.0009 0.0008
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0578 0.2167 0.2352
Echinococcus multilocularis casein kinase I alpha 0.0244 0.0643 0.0775
Trichomonas vaginalis CAMK family protein kinase 0.0608 0.2305 0.9564
Trichomonas vaginalis CAMK family protein kinase 0.0284 0.0826 0.3401
Entamoeba histolytica tyrosine kinase, putative 0.0105 0.0009 0.0014
Giardia lamblia Kinase, AGC PKA 0.0254 0.0688 0.2958
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0114 0.0047 0.0167
Entamoeba histolytica protein kinase domain containing protein 0.0105 0.0009 0.0014
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0226 0.0563 0.0678
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0116 0.0058 1
Schistosoma mansoni tyrosine kinase 0.0804 0.3199 0.5493
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0125 0.0101 0.011
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0252 0.0678 0.0817
Echinococcus multilocularis mitogen activated protein kinase 11 0.0358 0.1162 0.1405
Schistosoma mansoni tyrosine kinase 0.0105 0.0009 0.0008
Brugia malayi Protein kinase domain containing protein 0.0362 0.1183 0.1276
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0456 0.161 0.1747
Echinococcus multilocularis SH2 motif 0.0129 0.0118 0.0138
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0249 0.0664 0.066
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.075 0.2954 0.3206
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0129 0.0118 0.0208
Entamoeba histolytica protein kinase domain containing protein 0.0275 0.0783 0.2269
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0226 0.0563 0.0611
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0105 0.0009 0.0008
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0223 0.0548 0.0935
Echinococcus multilocularis serine:threonine protein kinase 3 0.0578 0.2167 0.2623
Loa Loa (eye worm) hypothetical protein 0.0272 0.077 0.0836
Loa Loa (eye worm) TK protein kinase 0.0432 0.1503 0.1631
Entamoeba histolytica protein kinase domain containing protein 0.0105 0.0009 0.0014
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.101 0.4139 0.4492
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0267 0.0748 0.0811
Schistosoma mansoni serine/threonine protein kinase 0.0302 0.091 0.1558
Entamoeba histolytica protein kinase, putative 0.0312 0.0955 0.277
Brugia malayi hypothetical protein 0.0223 0.0548 0.0585
Trichomonas vaginalis CMGC family protein kinase 0.045 0.1582 0.6553
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0105 0.0009 0.0006
Giardia lamblia Kinase, CMGC GSK 0.0289 0.0849 0.3658
Entamoeba histolytica hypothetical protein 0.0105 0.0009 0.0014
Entamoeba histolytica tyrosine kinase, putative 0.0105 0.0009 0.0014
Echinococcus granulosus tyrosine protein kinase pr2 0.0105 0.0009 0.0005
Trichomonas vaginalis STE family protein kinase 0.0306 0.0926 0.3819
Echinococcus granulosus roundabout 2 0.0125 0.0101 0.0097
Loa Loa (eye worm) TK protein kinase 0.0105 0.0009 0.001
Schistosoma mansoni cell adhesion molecule 0.0125 0.0101 0.0167
Brugia malayi P38 map kinase family protein 2 0.0358 0.1162 0.1253
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0105 0.0009 0.0008
Brugia malayi Protein kinase domain containing protein 0.0139 0.0162 0.0166
Loa Loa (eye worm) CDC7 protein kinase 0.045 0.1582 0.1718
Trichomonas vaginalis CAMK family protein kinase 0.0608 0.2305 0.9564
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0358 0.1162 0.5022
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0445 0.1817
Entamoeba histolytica protein kinase, putative 0.0159 0.0254 0.0729
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0105 0.0009 0.0014
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.1113 0.461 0.5585
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0312 0.0955 0.1037
Trichomonas vaginalis CMGC family protein kinase 0.0225 0.0555 0.2276
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.1351 0.5696 0.6183
Brugia malayi C1-like domain containing protein 0.0489 0.1764 0.1907
Entamoeba histolytica protein kinase, putative 0.0611 0.2318 0.674
Entamoeba histolytica protein kinase, putative 0.0105 0.0009 0.0014
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0223 0.0548 0.0544
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0105 0.0009 0.0008
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0306 0.0926 0.836
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0252 0.0678 0.0674
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0322 0.1 0.4314
Schistosoma mansoni serine/threonine protein kinase 0.0201 0.0445 0.0759
Loa Loa (eye worm) hypothetical protein 0.0105 0.0009 0.001
Trichomonas vaginalis CMGC family protein kinase 0.0129 0.0118 0.0452
Echinococcus multilocularis tyrosine protein kinase shark 0.0715 0.2794 0.3383
Schistosoma mansoni tyrosine kinase 0.1012 0.4148 0.7125
Schistosoma mansoni growth factor receptor-bound protein 0.0217 0.0522 0.089
Entamoeba histolytica protein kinase, putative 0.0193 0.041 0.1184
Schistosoma mansoni tyrosine kinase 0.0804 0.3199 0.5493
Plasmodium falciparum calcium-dependent protein kinase 4 0.0226 0.0563 0.505
Schistosoma mansoni serine/threonine protein kinase 0.045 0.1582 0.2714
Entamoeba histolytica protein kinase, putative 0.0105 0.0009 0.0014
Echinococcus multilocularis serine:threonine protein kinase N2 0.0292 0.0862 0.104
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0252 0.0678 0.2786
Trichomonas vaginalis AGC family protein kinase 0.012 0.0075 0.0275
Schistosoma mansoni tyrosine kinase 0.0176 0.0332 0.0563
Entamoeba histolytica protein kinase, putative 0.0303 0.0914 0.2649
Trichomonas vaginalis AGC family protein kinase 0.0254 0.0688 0.2829
Loa Loa (eye worm) hypothetical protein 0.0105 0.0009 0.001
Echinococcus multilocularis activated cdc42 kinase 1 0.0105 0.0009 0.0006
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0226 0.0563 0.2399
Loa Loa (eye worm) TK/FER protein kinase 0.0105 0.0009 0.001
Giardia lamblia Kinase, CAMK CAMKL 0.0201 0.0445 0.19
Loa Loa (eye worm) hypothetical protein 0.0252 0.0678 0.0736
Loa Loa (eye worm) TK/FER protein kinase 0.0105 0.0009 0.001
Echinococcus granulosus epidermal growth factor receptor 0.0909 0.3679 0.3676
Loa Loa (eye worm) TK/RYK protein kinase 0.0105 0.0009 0.001
Trichomonas vaginalis AGC family protein kinase 0.012 0.0075 0.0275
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0445 0.1817
Brugia malayi Fibronectin type III domain containing protein 0.0223 0.0548 0.0585
Schistosoma mansoni protein kinase 0.0105 0.0009 0.0008
Schistosoma mansoni serine/threonine protein kinase 0.0574 0.2148 0.3687
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0179 0.0345 0.14
Entamoeba histolytica serine/threonine protein kinase, putative 0.0201 0.0445 0.1285
Onchocerca volvulus 0.0144 0.0187 0.0341
Plasmodium vivax serine/threonine protein kinase, putative 0.0187 0.038 0.3387
Loa Loa (eye worm) serine/threonine protein kinase 0.0105 0.0009 0.001
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0129 0.0118 0.0473
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0322 0.1 0.9033
Entamoeba histolytica hypothetical protein 0.0105 0.0009 0.0014
Entamoeba histolytica protein kinase domain containing protein 0.0456 0.161 0.4677
Brugia malayi Tensin 0.0129 0.0118 0.0118
Echinococcus multilocularis tyrosine protein kinase HCK 0.0303 0.0914 0.1103
Echinococcus multilocularis tyrosine kinase 0.0234 0.0598 0.072
Echinococcus granulosus insulin growth factor 1 receptor beta 0.1047 0.4309 0.4307
Trichomonas vaginalis CMGC family protein kinase 0.0289 0.0849 0.3499
Giardia lamblia Kinase, CAMK CAMKL 0.0201 0.0445 0.19
Echinococcus multilocularis natriuretic peptide receptor 1 0.0105 0.0009 0.0006
Brugia malayi SH2 domain containing protein 0.0129 0.0118 0.0118
Entamoeba histolytica PH domain containing protein kinase, putative 0.0274 0.078 0.226
Entamoeba histolytica protein kinase domain containing protein 0.0105 0.0009 0.0014
Schistosoma mansoni hypothetical protein 0.0129 0.0118 0.0195
Echinococcus granulosus tyrosine protein kinase Fyn 0.0516 0.1886 0.1883
Schistosoma mansoni tyrosine kinase 0.0105 0.0009 0.0008
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0179 0.0345 0.1464
Loa Loa (eye worm) TK/FER protein kinase 0.0105 0.0009 0.001
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0516 0.1886 0.2282
Echinococcus granulosus c src tyrosine kinase 0.0318 0.0982 0.0978
Brugia malayi Protein kinase domain containing protein 0.0793 0.3152 0.3415
Onchocerca volvulus 0.0322 0.0998 0.1894
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0516 0.1886 0.2282
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0327 0.1022 0.2965
Echinococcus multilocularis protein kinase c iota type 0.0643 0.2466 0.2985
Echinococcus multilocularis mitogen activated protein kinase 11 0.0358 0.1162 0.1405
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0919 0.3725 0.3723
Trichomonas vaginalis CAMK family protein kinase 0.0608 0.2305 0.9564
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0325 0.1014 0.1225
Schistosoma mansoni kinase 0.065 0.2495 0.4283
Entamoeba histolytica protein kinase, putative 0.0275 0.0783 0.2269
Entamoeba histolytica protein kinase, putative 0.0159 0.0254 0.0729
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0345 0.1106 0.4777
Loa Loa (eye worm) TK/ROR protein kinase 0.0154 0.0232 0.0252
Giardia lamblia Kinase, CDC7 0.045 0.1582 0.6852
Entamoeba histolytica protein kinase, putative 0.0275 0.0783 0.2269
Loa Loa (eye worm) hypothetical protein 0.0201 0.0447 0.0485
Echinococcus multilocularis rho associated protein kinase 0.0732 0.287 0.3475
Entamoeba histolytica protein kinase, putative 0.0105 0.0009 0.0014
Plasmodium falciparum calcium-dependent protein kinase 3 0.0226 0.0563 0.505
Echinococcus granulosus cyclin dependent kinase 5 0.0267 0.0748 0.0744
Giardia lamblia Kinase, AGC PKA 0.0322 0.1 0.4314
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0516 0.1886 0.2282
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0183 0.0364 0.036
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0182 0.0359 0.3191
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0223 0.0548 0.0659
Entamoeba histolytica protein kinase domain containing protein 0.0105 0.0009 0.0014
Entamoeba histolytica protein kinase domain containing protein 0.0327 0.1022 0.2965
Leishmania major protein kinase A catalytic subunit isoform 1 0.0254 0.0688 0.2958
Schistosoma mansoni hypothetical protein 0.0229 0.0576 0.0984
Echinococcus granulosus casein kinase I alpha 0.0244 0.0643 0.0639
Echinococcus multilocularis SH2 domain containing protein 7 0.0129 0.0118 0.0138
Trichomonas vaginalis AGC family protein kinase 0.012 0.0075 0.0275
Schistosoma mansoni protein kinase 0.0105 0.0009 0.0008
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0325 0.1014 0.101
Loa Loa (eye worm) AUR protein kinase 0.0327 0.1022 0.1109
Schistosoma mansoni serine/threonine protein kinase 0.0362 0.1183 0.2027
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0105 0.0009 0.001
Trichomonas vaginalis CK1 family protein kinase 0.0244 0.0643 0.2642
Loa Loa (eye worm) hypothetical protein 0.0129 0.0118 0.0128
Loa Loa (eye worm) hypothetical protein 0.0201 0.0445 0.0483
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0322 0.1 0.9033
Brugia malayi serine/threonine kinase 12 0.0327 0.1022 0.1101
Onchocerca volvulus 0.0234 0.0598 0.1129
Echinococcus multilocularis tensin 0.0129 0.0118 0.0138
Loa Loa (eye worm) hypothetical protein 0.1351 0.5696 0.6183
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0226 0.0563 0.0678
Loa Loa (eye worm) TK protein kinase 0.0788 0.3129 0.3396
Echinococcus multilocularis PAK box P21 Rho binding 0.0144 0.0187 0.0222
Trichomonas vaginalis CMGC family protein kinase 0.0129 0.0118 0.0452
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0327 0.1022 0.2965
Echinococcus granulosus SH2 motif 0.0129 0.0118 0.0114
Schistosoma mansoni serine/threonine protein kinase 0.0529 0.1943 0.3333
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0105 0.0009 0.001
Entamoeba histolytica hypothetical protein 0.0105 0.0009 0.0014
Entamoeba histolytica protein kinase, putative 0.0105 0.0009 0.0014
Echinococcus granulosus titin 0.0158 0.0249 0.0245
Echinococcus multilocularis mitogen activated protein kinase 3 0.0129 0.0118 0.0138
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0154 0.0232 0.0228
Onchocerca volvulus Netrin receptor homolog 0.0114 0.0049 0.0077
Plasmodium falciparum calcium-dependent protein kinase 2 0.0226 0.0563 0.505
Loa Loa (eye worm) hypothetical protein 0.0223 0.0548 0.0594
Trichomonas vaginalis AGC family protein kinase 0.0631 0.241 1
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0129 0.0118 0.047
Echinococcus granulosus kinase suppressor of Ras 1 0.0105 0.0009 0.0005
Leishmania major protein kinase, putative 0.0179 0.0345 0.1464
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0445 0.1817
Loa Loa (eye worm) hypothetical protein 0.0129 0.0118 0.0128
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0289 0.0849 0.3658
Schistosoma mansoni serine/threonine protein kinase 0.0345 0.1106 0.1895
Loa Loa (eye worm) hypothetical protein 0.0105 0.0009 0.001
Brugia malayi putative serine/threonine kinase SADA gamma 0.0201 0.0445 0.0474
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0122 0.0088 0.0343
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0105 0.0009 0.0014
Echinococcus granulosus serine:threonine protein kinase 0.0256 0.0699 0.0696
Schistosoma mansoni tyrosine kinase 0.1245 0.5214 0.8959
Echinococcus multilocularis casein kinase I alpha 0.0244 0.0643 0.0775
Trichomonas vaginalis AGC family protein kinase 0.014 0.0167 0.0658
Toxoplasma gondii histone kinase SNF1, putative 0.0201 0.0445 0.1889
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0105 0.0009 0.001
Plasmodium falciparum casein kinase 1 0.0244 0.0643 0.5783
Trypanosoma cruzi polo-like protein kinase, putative 0.0608 0.2305 1
Brugia malayi casein kinase I 0.0244 0.0643 0.0689
Brugia malayi intracellular kinase 0.0289 0.0849 0.0913
Echinococcus multilocularis neuroglian 0.0125 0.0101 0.0118
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.019 0.0396 0.1687
Brugia malayi Stress-activated protein kinase jnk-1 0.0595 0.2244 0.2428
Schistosoma mansoni serine/threonine protein kinase 0.0345 0.1106 0.1895
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0129 0.0118 0.0128
Schistosoma mansoni protein kinase 0.0193 0.041 0.0699
Loa Loa (eye worm) RGC/RGC protein kinase 0.0105 0.0009 0.001
Brugia malayi STAT protein, DNA binding domain containing protein 0.0129 0.0118 0.0118
Toxoplasma gondii AGC kinase 0.0254 0.0688 0.2941
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0283 0.0822 0.3539
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.2121 0.9213 1
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0369 0.1213 0.121
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0456 0.161 0.1947
Entamoeba histolytica cell division protein kinase 2, putative 0.0267 0.0748 0.2166
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0549 0.2034 0.2462
Schistosoma mansoni tyrosine kinase 0.0105 0.0009 0.0008
Onchocerca volvulus 0.0313 0.0956 0.1815
Echinococcus granulosus casein kinase I alpha 0.0244 0.0643 0.0639
Leishmania major protein kinase, putative 0.0327 0.1022 0.4411
Loa Loa (eye worm) hypothetical protein 0.0129 0.0118 0.0128
Entamoeba histolytica casein kinase 1, putative 0.0244 0.0643 0.1862
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.014 0.0167 0.0658
Plasmodium vivax protein kinase, putative 0.0139 0.0164 0.1414
Trichomonas vaginalis CMGC family protein kinase 0.0312 0.0955 0.394
Loa Loa (eye worm) hypothetical protein 0.0129 0.0118 0.0128
Loa Loa (eye worm) hypothetical protein 0.0278 0.0798 0.0866
Schistosoma mansoni serine/threonine protein kinase 0.0183 0.0364 0.0618
Toxoplasma gondii AGC kinase 0.0254 0.0688 0.2941
Echinococcus granulosus receptor type guanylyl cyclase 0.0105 0.0009 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0187 0.038 0.0647
Schistosoma mansoni nephrin 0.0125 0.0101 0.0167
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0488 0.1757 0.1907
Echinococcus granulosus casein kinase I alpha 0.0244 0.0643 0.0639
Loa Loa (eye worm) hypothetical protein 0.0105 0.0009 0.001
Schistosoma mansoni tyrosine protein kinase 0.0105 0.0009 0.0008
Entamoeba histolytica protein kinase domain containing protein 0.0105 0.0009 0.0014
Echinococcus granulosus tyrosine protein kinase Blk 0.0432 0.1503 0.1499
Trichomonas vaginalis CAMK family protein kinase 0.0259 0.0709 0.2917
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0105 0.0009 0.0005
Schistosoma mansoni protein kinase 0.0977 0.3988 0.6851
Echinococcus granulosus tyrosine protein kinase Fyn 0.0516 0.1886 0.1883
Entamoeba histolytica tyrosine kinase, putative 0.0105 0.0009 0.0014
Schistosoma mansoni growth factor receptor-bound protein 0.0213 0.0501 0.0855
Brugia malayi Protein kinase domain containing protein 0.0645 0.2475 0.2679
Loa Loa (eye worm) hypothetical protein 0.0227 0.0565 0.0614
Brugia malayi hypothetical protein 0.0252 0.0678 0.0727
Echinococcus granulosus cGMP dependent protein kinase 1 0.0302 0.091 0.0906
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0201 0.0445 0.1817
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0611 0.2318 0.2516
Entamoeba histolytica cell division protein kinase 2, putative 0.0267 0.0748 0.2166
Schistosoma mansoni protein kinase C mu 0.0489 0.1764 0.3026
Loa Loa (eye worm) hypothetical protein 0.0149 0.021 0.0228
Echinococcus granulosus SH2 motif 0.0129 0.0118 0.0114
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0105 0.0009 0.0006
Schistosoma mansoni protein kinase 0.0105 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0284 0.0825 0.0895
Brugia malayi Furin-like cysteine rich region family protein 0.1378 0.582 0.6313
Trichomonas vaginalis AGC family protein kinase 0.0327 0.1022 0.4219
Loa Loa (eye worm) AGC/PKA protein kinase 0.0254 0.0688 0.0747
Echinococcus granulosus nervana 2 0.0249 0.0664 0.066
Echinococcus multilocularis mitogen activated protein kinase 14 0.0358 0.1162 0.1405
Schistosoma mansoni serine/threonine protein kinase 0.0595 0.2244 0.3851
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0226 0.0563 0.505
Entamoeba histolytica ankyrin repeat protein 0.0105 0.0009 0.0014
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0345 0.1106 0.4568
Echinococcus multilocularis aurora kinase A 0.0327 0.1022 0.1234
Onchocerca volvulus 0.0234 0.0598 0.1129
Schistosoma mansoni serine/threonine protein kinase 0.0452 0.1591 0.2728
Giardia lamblia Kinase, NEK 0.0114 0.0047 0.0167
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0159 0.0254 0.025
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0193 0.041 0.0493
Echinococcus multilocularis neuroglian 0.0237 0.061 0.0735
Giardia lamblia Kinase, NEK 0.0306 0.0926 0.3993
Schistosoma mansoni protein kinase 0.0327 0.1022 0.175
Schistosoma mansoni tyrosine kinase 0.0909 0.3679 0.6319
Trypanosoma cruzi aurora B kinase, putative 0.0327 0.1022 0.4411
Echinococcus multilocularis CDC7 cell division cycle 7 0.045 0.1582 0.1914
Schistosoma mansoni serine/threonine protein kinase 0.0456 0.161 0.2761
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0213 0.0501 0.0855
Loa Loa (eye worm) TK/CSK protein kinase 0.0105 0.0009 0.001
Trichomonas vaginalis AGC family protein kinase 0.014 0.0167 0.0658
Loa Loa (eye worm) AGC/PKA protein kinase 0.0254 0.0688 0.0747
Brugia malayi tRNA modification GTPase TrmE family protein 0.0129 0.0118 0.0118
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0254 0.0688 0.083
Toxoplasma gondii NEK kinase 0.0114 0.0047 0.0166
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0529 0.1944 0.1941
Onchocerca volvulus 0.0234 0.0598 0.1129
Schistosoma mansoni tyrosine kinase 0.0516 0.1886 0.3236
Leishmania major protein kinase, putative 0.0345 0.1106 0.4777
Schistosoma mansoni serine/threonine protein kinase 0.0549 0.2034 0.349
Brugia malayi Cam kinase protein 1 0.0226 0.0563 0.0602
Brugia malayi phosphoinositide-dependent protein kinase I 0.0183 0.0364 0.0385
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0254 0.0688 0.2829
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0267 0.0748 0.3217
Plasmodium falciparum casein kinase 2, alpha subunit 0.0225 0.0555 0.4981
Entamoeba histolytica protein kinase, putative 0.0183 0.0364 0.1048
Echinococcus granulosus NDR protein kinase 0.0362 0.1183 0.118
Trypanosoma brucei Serine/threonine-protein kinase NEK16, putative 0.0114 0.0047 0.016
Leishmania major protein kinase, putative 0.0345 0.1106 0.4777
Trichomonas vaginalis CAMK family protein kinase 0.0608 0.2305 0.9564
Brugia malayi Variant SH3 domain containing protein 0.0213 0.0501 0.0535
Schistosoma mansoni tyrosine kinase 0.1378 0.582 1
Brugia malayi protein kinase C II. 0.0459 0.1626 0.1757
Loa Loa (eye worm) hypothetical protein 0.0254 0.0688 0.0747
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0368 0.121 0.1313
Trichomonas vaginalis AGC family protein kinase 0.0631 0.241 1
Schistosoma mansoni serine/threonine protein kinase 0.0201 0.0445 0.0759
Echinococcus granulosus ephrin type A receptor 4 A 0.0249 0.0667 0.0664
Onchocerca volvulus Serine\/threonine kinase homolog 0.0608 0.2305 0.44
Entamoeba histolytica protein kinase , putative 0.0327 0.1022 0.2965
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0825 0.3298 0.3295
Trichomonas vaginalis STE family protein kinase 0.0114 0.0047 0.016
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0106 0.0012 0.0023
Entamoeba histolytica protein kinase domain containing protein 0.0179 0.0345 0.0993
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0345 0.1106 0.12
Loa Loa (eye worm) casein kinase 0.0266 0.0745 0.0809
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0129 0.0118 0.0128
Echinococcus granulosus suppressor of cytokine signaling 7 0.0129 0.0118 0.0114
Plasmodium vivax unspecified product 0.0225 0.0555 0.4981
Echinococcus multilocularis signal transduction protein lnk realted 0.0129 0.0118 0.0138
Echinococcus multilocularis tyrosine protein kinase Blk 0.0432 0.1503 0.1817
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0289 0.0849 0.1453
Trypanosoma cruzi Serine/threonine-protein kinase NEK16, putative 0.0114 0.0047 0.0167
Loa Loa (eye worm) TK/FER protein kinase 0.0234 0.0598 0.0649
Loa Loa (eye worm) TK/FER protein kinase 0.0105 0.0009 0.001
Echinococcus multilocularis casein kinase I alpha 0.0244 0.0643 0.0775
Trichomonas vaginalis serine/threonine-protein kinase, putative 0.012 0.0075 0.0275
Trichomonas vaginalis CMGC family protein kinase 0.045 0.1582 0.6553
Trypanosoma brucei rac serine-threonine kinase, putative 0.0631 0.241 1
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0418 0.1437 0.1737
Echinococcus granulosus calcium dependent protein kinase 0.0153 0.0227 0.0223
Echinococcus multilocularis twitchin 0.0122 0.0088 0.0102
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.05 0.1811 0.2191
Entamoeba histolytica protein kinase domain containing protein 0.0312 0.0955 0.277
Loa Loa (eye worm) hypothetical protein 0.0127 0.0109 0.0118
Echinococcus multilocularis activin receptor type 0.0179 0.0345 0.0414
Brugia malayi Protein kinase domain containing protein 0.0631 0.241 0.2609
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0445 0.1817
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0445 0.1817
Echinococcus multilocularis protein tyrosine kinase 0.1245 0.5214 0.6318
Loa Loa (eye worm) hypothetical protein 0.0183 0.0367 0.0398
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0408 0.1393 0.1512
Schistosoma mansoni protein kinase 0.0529 0.1944 0.3336
Leishmania major casein kinase II, putative 0.0225 0.0555 0.2379
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0116 0.0058 1
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0226 0.0563 0.0678
Echinococcus granulosus serine/threonine protein kinase 0.0342 0.1092 0.1088
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0234 0.0598 0.173
Entamoeba histolytica protein kinase, putative 0.0631 0.241 0.7008
Echinococcus granulosus tyrosine kinase 0.0105 0.0009 0.0005
Onchocerca volvulus Serine\/threonine kinase homolog 0.0369 0.1213 0.2308
Echinococcus granulosus twitchin 0.031 0.0946 0.0942
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0188 0.0387 0.0464
Schistosoma mansoni tyrosine kinase 0.0105 0.0009 0.0008
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0432 0.1503 0.1817
Entamoeba histolytica hypothetical protein, conserved 0.0105 0.0009 0.0014
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0289 0.0849 0.0922
Echinococcus granulosus retinal guanylyl cyclase 2 0.0105 0.0009 0.0005
Trichomonas vaginalis AGC family protein kinase 0.012 0.0075 0.0275
Entamoeba histolytica tyrosine kinase, putative 0.0105 0.0009 0.0014
Brugia malayi SH2 domain containing protein 0.0917 0.3718 0.403
Schistosoma mansoni serine/threonine protein kinase 0.1074 0.4431 0.7612
Schistosoma mansoni atypical protein kinase C 0.0657 0.2528 0.4341
Loa Loa (eye worm) hypothetical protein 0.0129 0.0118 0.0128
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0259 0.0709 0.0706
Loa Loa (eye worm) hypothetical protein 0.0127 0.0109 0.0118
Echinococcus granulosus signal transduction protein lnk realted 0.0129 0.0118 0.0114
Trichomonas vaginalis AGC family protein kinase 0.014 0.0167 0.0658
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0203 0.0454 0.131
Trypanosoma cruzi casein kinase, putative 0.0244 0.0643 0.2762
Giardia lamblia Kinase, CMGC DYRK 0.0312 0.0955 0.412
Loa Loa (eye worm) hypothetical protein 0.0129 0.0118 0.0128
Loa Loa (eye worm) hypothetical protein 0.0416 0.1428 0.155
Entamoeba histolytica protein kinase, putative 0.0105 0.0009 0.0014
Loa Loa (eye worm) hypothetical protein 0.0105 0.0009 0.001
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0252 0.0678 0.2913
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0267 0.0748 0.3199
Entamoeba histolytica tyrosine kinase, putative 0.0105 0.0009 0.0014
Schistosoma mansoni serine/threonine-protein kinase 0.0342 0.1092 0.187
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0225 0.0555 0.0603
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0125 0.0101 0.0118
Brugia malayi Protein kinase domain containing protein 0.0234 0.0598 0.064
Schistosoma mansoni GTPase activating protein 0.0129 0.0118 0.0195
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0226 0.0563 0.505
Brugia malayi Protein kinase domain containing protein 0.0234 0.0598 0.064
Loa Loa (eye worm) STAT protein 0.0129 0.0118 0.0128
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0267 0.0748 0.0744
Entamoeba histolytica protein kinase domain containing protein 0.0105 0.0009 0.0014
Trichomonas vaginalis AGC family protein kinase 0.012 0.0075 0.0275
Loa Loa (eye worm) TK/FER protein kinase 0.0234 0.0598 0.0649
Echinococcus granulosus SHC transforming protein 3 0.0129 0.0118 0.0114
Plasmodium falciparum protein serine/threonine kinase-1 0.0345 0.1106 1
Entamoeba histolytica serine/threonine kinase, putative 0.0105 0.0009 0.0014
Brugia malayi Protein kinase domain containing protein 0.0434 0.1509 0.1629
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0256 0.0699 0.0759
Schistosoma mansoni tyrosine kinase 0.0552 0.2048 0.3514
Loa Loa (eye worm) RGC/RGC protein kinase 0.0105 0.0009 0.001
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0159 0.0254 0.025
Schistosoma mansoni tyrosine kinase 0.0105 0.0009 0.0008
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0047 0.016
Echinococcus granulosus tyrosine protein kinase Src42A 0.0516 0.1886 0.1883
Schistosoma mansoni tyrosine kinase 0.0105 0.0009 0.0008
Echinococcus multilocularis NCK adaptor protein 0.0217 0.0522 0.0628
Onchocerca volvulus 0.0129 0.0118 0.0208
Schistosoma mansoni serine/threonine protein kinase 0.0254 0.0688 0.1176
Leishmania major protein kinase, putative,serine/threonine-protein kinase Nek1, putative 0.0114 0.0047 0.0167
Toxoplasma gondii casein kinase I 0.0244 0.0643 0.2747
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0358 0.1162 0.4803
Entamoeba histolytica protein kinase domain containing protein 0.0289 0.0849 0.2461
Loa Loa (eye worm) TK/FER protein kinase 0.0105 0.0009 0.001
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0129 0.0118 0.0138
Trichomonas vaginalis AGC family protein kinase 0.0362 0.1183 0.489
Schistosoma mansoni tyrosine kinase 0.0105 0.0009 0.0008
Onchocerca volvulus 0.0252 0.0678 0.1282
Trichomonas vaginalis AGC family protein kinase 0.012 0.0075 0.0275
Entamoeba histolytica SH2 domain containing protein 0.0129 0.0118 0.0331
Trichomonas vaginalis AGC family protein kinase 0.0306 0.0926 0.3819
Entamoeba histolytica protein kinase, putative 0.0105 0.0009 0.0014
Trypanosoma brucei protein kinase, putative 0.0129 0.0118 0.0452
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0105 0.0009 0.0006
Echinococcus multilocularis casein kinase ii subunit alpha 0.0225 0.0555 0.0669
Entamoeba histolytica tyrosine kinase, putative 0.0105 0.0009 0.0014
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0105 0.0009 0.0008
Brugia malayi Protein kinase domain containing protein 0.0452 0.1591 0.1718
Schistosoma mansoni serine/threonine protein kinase 0.0122 0.0088 0.0144
Trypanosoma cruzi Protein kinase B 0.0342 0.1092 0.4715
Trichomonas vaginalis AGC family protein kinase 0.0408 0.1393 0.5766
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0159 0.0254 0.0303
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0326 0.1015 0.1226
Loa Loa (eye worm) hypothetical protein 0.0256 0.0699 0.0759
Echinococcus multilocularis serine:threonine protein kinase 0.0256 0.0699 0.0843
Entamoeba histolytica protein kinase domain containing protein 0.0105 0.0009 0.0014
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0335 0.1057 0.4366
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0254 0.0688 0.2958
Trichomonas vaginalis serine/threonine-protein kinase ypk, putative 0.012 0.0075 0.0275
Loa Loa (eye worm) hypothetical protein 0.0322 0.0998 0.1083
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0516 0.1886 0.2282
Brugia malayi Variant SH3 domain containing protein 0.0223 0.0548 0.0585
Loa Loa (eye worm) hypothetical protein 0.0229 0.0576 0.0626
Echinococcus granulosus CDC7 cell division cycle 7 0.045 0.1582 0.1579
Loa Loa (eye worm) SH2 domain-containing protein 0.0129 0.0118 0.0128
Trichomonas vaginalis CK1 family protein kinase 0.0244 0.0643 0.2642
Echinococcus granulosus roundabout 2 0.0125 0.0101 0.0097
Entamoeba histolytica protein kinase, putative 0.0226 0.0563 0.1628
Entamoeba histolytica tyrosine kinase, putative 0.0105 0.0009 0.0014
Trichomonas vaginalis CMGC family protein kinase 0.045 0.1582 0.6553
Schistosoma mansoni serine/threonine protein kinase 0.0418 0.1437 0.2463
Loa Loa (eye worm) TK/FER protein kinase 0.0917 0.3718 0.4036
Trichomonas vaginalis CMGC family protein kinase 0.0225 0.0555 0.2276
Brugia malayi SH2 domain containing protein 0.0129 0.0118 0.0118
Trichomonas vaginalis AGC family protein kinase 0.014 0.0167 0.0658
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0369 0.1213 0.1317
Loa Loa (eye worm) hypothetical protein 0.0323 0.1005 0.1091
Echinococcus granulosus cGMP dependent protein kinase 1 0.0302 0.091 0.0906
Schistosoma mansoni serine/threonine protein kinase 0.0122 0.0088 0.0144
Entamoeba histolytica protein kinase, putative 0.0631 0.241 0.7008
Echinococcus granulosus titin 0.0158 0.0249 0.0245
Giardia lamblia Kinase, STE STE20 0.0193 0.041 0.1748
Echinococcus granulosus Glutaredoxin protein 5 0.0249 0.0666 0.0663
Loa Loa (eye worm) TK/FER protein kinase 0.0234 0.0598 0.0649
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0267 0.0748 0.0811
Giardia lamblia Kinase, CMGC MAPK 0.0129 0.0118 0.0473
Echinococcus multilocularis N chimaerin 0.0223 0.0548 0.0659
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0129 0.0118 0.0138
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0312 0.0955 0.412
Loa Loa (eye worm) hypothetical protein 0.0252 0.0678 0.0736
Echinococcus multilocularis tensin 0.0129 0.0118 0.0138
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0345 0.1106 0.4777
Echinococcus granulosus dual specificity protein kinase clk2 0.0345 0.1106 0.1102
Echinococcus multilocularis cyclin dependent kinase 1 0.0267 0.0748 0.0902
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0187 0.038 0.1609
Echinococcus granulosus roundabout 2 0.0313 0.0959 0.0955
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0344 0.1101 0.1195
Plasmodium falciparum calcium-dependent protein kinase 5 0.0226 0.0563 0.505
Loa Loa (eye worm) hypothetical protein 0.0105 0.0009 0.001
Echinococcus granulosus tensin 0.0129 0.0118 0.0114
Entamoeba histolytica protein kinase domain containing protein 0.0105 0.0009 0.0014
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0254 0.0688 0.2958
Echinococcus granulosus retinal guanylyl cyclase 2 0.0105 0.0009 0.0005
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0254 0.0688 0.083
Loa Loa (eye worm) TK/INSR protein kinase 0.1012 0.4148 0.4502
Plasmodium falciparum NIMA related kinase 2 0.0114 0.0047 0.035
Echinococcus granulosus N chimaerin 0.0223 0.0548 0.0544
Echinococcus granulosus casein kinase I gamma 0.034 0.1081 0.1078
Echinococcus granulosus cyclin dependent kinase 0.0267 0.0748 0.0744
Echinococcus multilocularis serine:threonine protein kinase 0.0256 0.0699 0.0843
Schistosoma mansoni hypothetical protein 0.0129 0.0118 0.0195
Echinococcus multilocularis casein kinase I delta 0.0244 0.0643 0.0775
Entamoeba histolytica protein kinase, putative 0.0105 0.0009 0.0014
Schistosoma mansoni serine/threonine protein kinase 0.026 0.0715 0.1222
Loa Loa (eye worm) hypothetical protein 0.0812 0.3238 0.3514
Entamoeba histolytica protein kinase, putative 0.0327 0.1022 0.2965
Schistosoma mansoni hypothetical protein 0.0229 0.0576 0.0984
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0608 0.2305 0.2502
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0105 0.0009 0.0014
Echinococcus granulosus aurora kinase A 0.0327 0.1022 0.1018
Plasmodium falciparum protein kinase 5 0.0267 0.0748 0.6734
Entamoeba histolytica protein kinase, putative 0.0164 0.0279 0.0802
Echinococcus granulosus STE20 serine:threonine protein kinase 0.1113 0.461 0.4608
Echinococcus multilocularis mitogen activated protein kinase 14 0.0358 0.1162 0.1405
Entamoeba histolytica protein kinase, putative 0.0106 0.0012 0.0023
Loa Loa (eye worm) TK/FER protein kinase 0.0105 0.0009 0.001
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0489 0.1764 0.1907
Brugia malayi Protein kinase domain containing protein 0.0183 0.0364 0.0385
Brugia malayi Protein kinase domain containing protein 0.1351 0.5696 0.6179
Echinococcus multilocularis 0.0129 0.0118 0.0138
Echinococcus multilocularis tyrosine protein kinase Srms 0.0432 0.1503 0.1817
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0252 0.0678 0.2913
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0445 0.1817
Leishmania major protein kinase, putative 0.0226 0.0563 0.2412
Loa Loa (eye worm) TK protein kinase 0.0105 0.0009 0.001
Loa Loa (eye worm) TK/FER protein kinase 0.0234 0.0598 0.0649
Loa Loa (eye worm) TK protein kinase 0.0105 0.0009 0.001
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0486 0.1747 0.2114
Loa Loa (eye worm) TK protein kinase 0.0105 0.0009 0.001
Schistosoma mansoni serine/threonine protein kinase 0.0303 0.0913 0.1562
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0358 0.1162 0.5022
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0226 0.0563 0.0559
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.019 0.0396 0.1143
Schistosoma mansoni nephrin 0.0272 0.0771 0.1319
Brugia malayi serine/threonine-protein kinase PAK 7 0.0522 0.1913 0.2068
Schistosoma mansoni serine/threonine protein kinase 0.0114 0.0047 0.0075
Onchocerca volvulus 0.0129 0.0118 0.0208
Echinococcus granulosus contactin 0.0125 0.0101 0.0097
Echinococcus granulosus Protein kinase C brain isozyme 0.0549 0.2034 0.2031
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0358 0.1162 0.1262
Trichomonas vaginalis AGC family protein kinase 0.0183 0.0364 0.1477
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0105 0.0009 0.0014
Loa Loa (eye worm) hypothetical protein 0.0129 0.0118 0.0128
Echinococcus multilocularis receptor type guanylyl cyclase 0.0105 0.0009 0.0006
Onchocerca volvulus 0.0129 0.0118 0.0208
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0312 0.0955 0.412
Trypanosoma cruzi cdc2-related kinase 3 0.0267 0.0748 0.3217
Echinococcus granulosus hypothetical protein 0.0272 0.077 0.0766
Giardia lamblia Aurora kinase 0.0327 0.1022 0.4411
Plasmodium falciparum serine/threonine protein kinase 0.0187 0.038 0.3387
Schistosoma mansoni protein kinase 0.0596 0.225 0.3862
Brugia malayi Immunoglobulin I-set domain containing protein 0.0125 0.0101 0.01
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0516 0.1886 0.1883
Brugia malayi Immunoglobulin I-set domain containing protein 0.0125 0.0101 0.01
Entamoeba histolytica serine/threonine kinase, putative 0.0105 0.0009 0.0014
Echinococcus granulosus natriuretic peptide receptor 1 0.0105 0.0009 0.0005
Brugia malayi Egg laying defective protein 4 0.0302 0.091 0.0979
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0608 0.2305 0.2302
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0226 0.0563 0.505
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0122 0.0088 0.0328
Brugia malayi SH2 domain containing protein 0.0129 0.0118 0.0118
Brugia malayi Protein kinase domain containing protein 0.0408 0.1393 0.1504
Giardia lamblia Kinase, AGC AKT 0.0263 0.073 0.3139
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0105 0.0009 0.0014
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0418 0.1437 0.1559
Trichomonas vaginalis AGC family protein kinase 0.012 0.0075 0.0275
Trichomonas vaginalis CMGC family protein kinase 0.0225 0.0555 0.2276
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0552 0.2048 0.2045
Entamoeba histolytica protein kinase, putative 0.0105 0.0009 0.0014
Brugia malayi Sex muscle abnormal protein 5 0.0213 0.0501 0.0535
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0201 0.0445 0.19
Loa Loa (eye worm) hypothetical protein 0.0125 0.0101 0.011
Plasmodium falciparum NIMA related kinase 1 0.0306 0.0926 0.836
Entamoeba histolytica protein kinase, putative 0.0187 0.038 0.1096
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0116 0.0058 1
Leishmania major protein kinase A catalytic subunit isoform 2 0.0254 0.0688 0.2958
Trichomonas vaginalis AGC family protein kinase 0.012 0.0075 0.0275
Schistosoma mansoni vam6/vps39 related 0.0252 0.0678 0.1159
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0254 0.0688 0.083
Leishmania major protein kinase, putative 0.0114 0.0047 0.0167
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0302 0.091 0.3902
Schistosoma mansoni serine/threonine protein kinase 0.0105 0.0009 0.0008
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0105 0.0009 0.0006
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0125 0.0101 0.0118
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0977 0.3988 0.3986
Trichomonas vaginalis AGC family protein kinase 0.0631 0.241 1
Schistosoma mansoni tensin-related 0.0129 0.0118 0.0195
Echinococcus multilocularis protein kinase shaggy 0.0289 0.0849 0.1025
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0188 0.0387 0.0658
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0275 0.0783 0.085
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0289 0.0849 0.1025
Echinococcus granulosus serine:threonine protein kinase 0.0256 0.0699 0.0696
Brugia malayi map kinase activated protein kinase protein 2 0.0887 0.358 0.388
Onchocerca volvulus 0.0244 0.0643 0.1215
Echinococcus granulosus Immunoglobulin 0.0188 0.0387 0.0383
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0213 0.0501 0.0544
Loa Loa (eye worm) hypothetical protein 0.0812 0.3238 0.3514
Echinococcus multilocularis calcium activated potassium channel 0.0303 0.0913 0.1102
Schistosoma mansoni serine/threonine protein kinase 0.034 0.1081 0.1852
Loa Loa (eye worm) hypothetical protein 0.0213 0.0501 0.0544
Entamoeba histolytica protein kinase domain containing protein 0.0105 0.0009 0.0014
Echinococcus granulosus activated cdc42 kinase 1 0.0105 0.0009 0.0005
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0552 0.2048 0.2478
Echinococcus multilocularis calcium dependent protein kinase 0.0153 0.0227 0.027
Loa Loa (eye worm) TK/FER protein kinase 0.0234 0.0598 0.0649
Schistosoma mansoni serine/threonine RGC 0.0105 0.0009 0.0008
Echinococcus multilocularis tyrosine protein kinase csk 0.0105 0.0009 0.0006
Echinococcus granulosus tyrosine protein kinase HCK 0.0303 0.0914 0.091
Brugia malayi SH2 domain containing protein 0.0129 0.0118 0.0118
Leishmania major protein kinase A catalytic subunit 0.0254 0.0688 0.2958
Trichomonas vaginalis AGC family protein kinase 0.014 0.0167 0.0658
Schistosoma mansoni protein kinase 0.0977 0.3988 0.6851
Brugia malayi cell division control protein 2 homolog 0.0267 0.0748 0.0803
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0047 0.016
Schistosoma mansoni serine/threonine protein kinase 0.0226 0.0563 0.0961
Brugia malayi Immunoglobulin I-set domain containing protein 0.0106 0.0014 0.0006
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0105 0.0009 0.0014
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0793 0.3152 0.3421
Trichomonas vaginalis AGC family protein kinase 0.014 0.0167 0.0658
Echinococcus multilocularis casein kinase i 0.0244 0.0643 0.0775
Onchocerca volvulus 0.017 0.0307 0.0571
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0114 0.0047 0.0167
Schistosoma mansoni protein kinase 0.0105 0.0009 0.0008
Echinococcus granulosus tyrosine kinase 0.0234 0.0598 0.0594
Echinococcus multilocularis rac serine:threonine kinase 0.0342 0.1092 0.1319
Echinococcus granulosus protein kinase C gamma type 0.0454 0.1604 0.16
Entamoeba histolytica protein kinase, putative 0.0105 0.0009 0.0014
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0793 0.3152 0.6022
Loa Loa (eye worm) hypothetical protein 0.0313 0.0956 0.1038
Brugia malayi Protein kinase c protein 2 0.026 0.0716 0.0768
Schistosoma mansoni serine/threonine protein kinase 0.0369 0.1213 0.2079
Brugia malayi p70 ribosomal S6 kinase beta 0.0611 0.2318 0.2509
Echinococcus multilocularis tyrosine protein kinase pr2 0.0105 0.0009 0.0006
Loa Loa (eye worm) RGC/RGC protein kinase 0.0105 0.0009 0.001
Echinococcus multilocularis SH2 motif 0.0129 0.0118 0.0138
Brugia malayi protein kinase C3,putative 0.0354 0.1148 0.1237
Trichomonas vaginalis CAMK family protein kinase 0.0259 0.0709 0.2917
Schistosoma mansoni serine/threonine protein kinase 0.0887 0.358 0.6148
Trypanosoma cruzi p21-activated kinase 3, putative 0.0122 0.0088 0.0343
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0187 0.038 0.0413
Loa Loa (eye worm) TK protein kinase 0.0303 0.0914 0.0992
Leishmania major serine/threonine-protein kinase, putative 0.0114 0.0047 0.0167
Echinococcus multilocularis tyrosine kinase 0.0105 0.0009 0.0006
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0244 0.0643 0.2762
Echinococcus multilocularis tyrosine protein kinase Abl 0.0497 0.1797 0.2174
Brugia malayi Hr1 repeat family protein 0.0654 0.2517 0.2724
Schistosoma mansoni serine/threonine protein kinase 0.0158 0.0249 0.0421
Schistosoma mansoni serine/threonine protein kinase 0.0793 0.3152 0.5412
Mycobacterium ulcerans hypothetical protein 0.0229 0.0574 0.5
Schistosoma mansoni tyrosine kinase 0.0105 0.0009 0.0008
Trypanosoma cruzi cdc2-related kinase 1 0.0267 0.0748 0.3217
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0608 0.2305 0.2791
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0226 0.0563 0.2307
Echinococcus multilocularis transfer RNA-Thr 0.0105 0.0009 0.0006
Entamoeba histolytica protein kinase domain containing protein 0.0105 0.0009 0.0014
Echinococcus granulosus activin receptor type 0.0179 0.0345 0.0341
Loa Loa (eye worm) TK/FAK protein kinase 0.1259 0.5276 0.5727
Schistosoma mansoni hypothetical protein 0.0105 0.0009 0.0008
Schistosoma mansoni ste20-related kinase 0.0461 0.1635 0.2805
Trichomonas vaginalis CMGC family protein kinase 0.0225 0.0555 0.2276
Loa Loa (eye worm) hypothetical protein 0.0201 0.0447 0.0485
Schistosoma mansoni serine/threonine protein kinase 0.0199 0.0439 0.0748
Echinococcus multilocularis epidermal growth factor receptor 0.1378 0.582 0.7052
Giardia lamblia Kinase, CMGC GSK 0.0289 0.0849 0.3658
Echinococcus multilocularis 0.0272 0.077 0.0929
Brugia malayi serine/threonine-protein kinase 6 0.0327 0.1022 0.1101
Echinococcus multilocularis serine threonine protein kinase 0.0454 0.1604 0.194
Entamoeba histolytica protein kinase domain containing protein 0.0105 0.0009 0.0014
Loa Loa (eye worm) AGC/NDR protein kinase 0.0362 0.1183 0.1284
Entamoeba histolytica tyrosine kinase, putative 0.0105 0.0009 0.0014
Loa Loa (eye worm) AGC/PKN protein kinase 0.0654 0.2517 0.2732
Onchocerca volvulus 0.0129 0.0118 0.0208
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0193 0.041 0.0407
Entamoeba histolytica hypothetical protein 0.0856 0.3437 1
Entamoeba histolytica protein kinase domain containing protein 0.0105 0.0009 0.0014
Echinococcus granulosus c-Jun N-terminal kinases 0.0595 0.2244 0.224
Loa Loa (eye worm) RGC/RGC protein kinase 0.0105 0.0009 0.001
Brugia malayi Protein kinase domain containing protein 0.0275 0.0783 0.0841
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0226 0.0563 0.0602
Echinococcus multilocularis dual specificity 0.0275 0.0783 0.0945
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0226 0.0563 0.2399
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0254 0.0688 0.0684
Echinococcus multilocularis SHC transforming protein 3 0.0129 0.0118 0.0138
Schistosoma mansoni protein kinase 0.0434 0.1509 0.2587
Echinococcus granulosus dual specificity 0.0312 0.0955 0.0951
Entamoeba histolytica protein kinase domain containing protein 0.0289 0.0849 0.2461
Echinococcus granulosus tyrosine protein kinase 0.0645 0.2475 0.2472
Brugia malayi hypothetical protein 0.0127 0.0109 0.0109
Echinococcus multilocularis integrin linked protein kinase 0.0105 0.0009 0.0006
Brugia malayi Casein kinase II, alpha chain 0.0225 0.0555 0.0594
Entamoeba histolytica protein kinase domain containing protein 0.0105 0.0009 0.0014
Brugia malayi Protein kinase domain containing protein 0.1259 0.5276 0.5723
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0327 0.1022 0.1018
Brugia malayi serine/threonine-protein kinase plk-2 0.0608 0.2305 0.2495
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0105 0.0009 0.0008
Echinococcus granulosus hypothetical protein 0.0129 0.0118 0.0114
Brugia malayi RhoGAP domain containing protein 0.0223 0.0548 0.0585
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0275 0.0783 0.337
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0445 0.1817
Loa Loa (eye worm) TK/FER protein kinase 0.0234 0.0598 0.0649
Giardia lamblia Kinase, NEK 0.0306 0.0926 0.3993
Loa Loa (eye worm) hypothetical protein 0.0129 0.0118 0.0128
Trichomonas vaginalis AGC family protein kinase 0.0327 0.1022 0.4219
Schistosoma mansoni tyrosine kinase 0.0195 0.042 0.0716
Brugia malayi Kinase associated domain 1 family protein 0.0229 0.0576 0.0617
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0793 0.3152 0.3149
Trichomonas vaginalis conserved hypothetical protein 0.0107 0.0015 0.0026
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0445 0.1817
Schistosoma mansoni tensin 0.0129 0.0118 0.0195
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0486 0.1747 0.1744
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0122 0.0088 0.0095
Echinococcus granulosus casein kinase ii subunit alpha 0.0225 0.0555 0.0552
Trichomonas vaginalis CK1 family protein kinase 0.0244 0.0643 0.2642
Echinococcus granulosus tyrosine protein kinase ABL1 0.0701 0.2731 0.2728
Brugia malayi Protein kinase domain containing protein 0.1351 0.5696 0.6179
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0105 0.0009 0.0014
Brugia malayi Tyrosine-protein kinase abl-1 0.0497 0.1797 0.1943
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0129 0.0118 0.0138
Schistosoma mansoni tyrosine kinase 0.0909 0.3679 0.6319
Schistosoma mansoni protein kinase 0.0105 0.0009 0.0008
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0105 0.0009 0.0014
Brugia malayi Variant SH3 domain containing protein 0.0213 0.0501 0.0535
Schistosoma mansoni tyrosine kinase 0.0105 0.0009 0.0008
Echinococcus granulosus dual specificity 0.0312 0.0955 0.0951
Loa Loa (eye worm) hypothetical protein 0.0129 0.0118 0.0128
Trichomonas vaginalis AGC family protein kinase 0.012 0.0075 0.0275
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0552 0.2048 0.2479
Echinococcus multilocularis serine:threonine protein kinase 38 0.0362 0.1183 0.143
Toxoplasma gondii CMGC kinase, CK2 family 0.0225 0.0555 0.2366
Trichomonas vaginalis AGC family protein kinase 0.0183 0.0364 0.1477
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0252 0.0678 0.1159
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0187 0.038 0.1618
Onchocerca volvulus 0.0732 0.287 0.5481
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0223 0.0548 0.0935
Loa Loa (eye worm) TK/FER protein kinase 0.0105 0.0009 0.001
Entamoeba histolytica casein kinase, putative 0.0244 0.0643 0.1862
Schistosoma mansoni tyrosine kinase 0.0715 0.2794 0.4797
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0445 0.1817
Echinococcus granulosus mitogen activated protein kinase 11 0.0358 0.1162 0.1159
Entamoeba histolytica receptor protein kinase, putative 0.0105 0.0009 0.0014
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0358 0.1162 0.5022
Echinococcus multilocularis Glutaredoxin protein 5 0.0249 0.0666 0.0803
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0522 0.1913 0.2076
Brugia malayi Protein kinase domain containing protein 0.0825 0.3298 0.3573
Schistosoma mansoni protein kinase 0.0977 0.3988 0.6851
Trypanosoma cruzi casein kinase, putative 0.0244 0.0643 0.2762
Brugia malayi Protein kinase domain containing protein 0.0429 0.1485 0.1604
Trichomonas vaginalis AGC family protein kinase 0.0631 0.241 1
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0522 0.1914 0.1911
Echinococcus granulosus protein tyrosine kinase 0.1245 0.5214 0.5212
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0306 0.0926 0.3971
Entamoeba histolytica tyrosin kinase, putative 0.0105 0.0009 0.0014
Echinococcus multilocularis c src tyrosine kinase 0.0318 0.0982 0.1185
Echinococcus granulosus protein kinase 0.0105 0.0009 0.0005
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0445 0.1817
Loa Loa (eye worm) hypothetical protein 0.0234 0.0598 0.0649
Brugia malayi Pleckstrin Homology Domain 0.0114 0.0051 0.0045
Echinococcus granulosus neuroglian 0.0237 0.061 0.0606
Brugia malayi Immunoglobulin I-set domain containing protein 0.0125 0.0101 0.01
Trypanosoma cruzi cdc2-related kinase 3 0.0267 0.0748 0.3217
Schistosoma mansoni cell adhesion molecule 0.0264 0.0736 0.1258
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1428 0.6051 0.6567
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.011 0.003 0.0031
Brugia malayi hypothetical protein 0.05 0.1811 0.1958
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0244 0.0643 0.0698
Loa Loa (eye worm) hypothetical protein 0.0193 0.0412 0.0447
Schistosoma mansoni cell adhesion molecule 0.0125 0.0101 0.0167
Trichomonas vaginalis AGC family protein kinase 0.012 0.0075 0.0275
Loa Loa (eye worm) TK/Met protein kinase 0.0105 0.0009 0.001
Toxoplasma gondii NEK kinase 0.0114 0.0047 0.0166
Brugia malayi Protein kinase domain containing protein 0.0363 0.1187 0.128
Echinococcus multilocularis expressed protein 0.0187 0.038 0.0456
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0193 0.041 0.0407
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0887 0.358 0.3886
Trichomonas vaginalis AGC family protein kinase 0.014 0.0167 0.0658
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0312 0.0955 0.4097
Schistosoma mansoni serine/threonine protein kinase 0.0105 0.0009 0.0008
Trichomonas vaginalis cAMP-dependent protein kinase catalytic subunit, putative 0.012 0.0075 0.0275
Brugia malayi Protein kinase domain containing protein 0.0234 0.0598 0.064
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0105 0.0009 0.0006
Entamoeba histolytica protein kinase domain containing protein 0.0105 0.0009 0.0014
Echinococcus granulosus neuroglian 0.0125 0.0101 0.0097
Echinococcus granulosus protein kinase 0.0344 0.1101 0.1097
Schistosoma mansoni serine/threonine protein kinase 0.0327 0.1022 0.175
Loa Loa (eye worm) TK/EPH protein kinase 0.0289 0.0848 0.092
Schistosoma mansoni SH2A 0.0129 0.0118 0.0195
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0332 0.1043 0.126
Trichomonas vaginalis TKL family protein kinase 0.0107 0.0015 0.0026
Schistosoma mansoni suppressor of cytokine signaling 0.0129 0.0118 0.0195
Brugia malayi hypothetical protein 0.0234 0.0598 0.064
Trichomonas vaginalis AGC family protein kinase 0.014 0.0167 0.0658
Loa Loa (eye worm) AGC/AKT protein kinase 0.0631 0.241 0.2616
Schistosoma mansoni serine/threonine kinase 0.0488 0.1757 0.3014
Onchocerca volvulus 0.0129 0.0118 0.0208
Entamoeba histolytica hypothetical protein 0.0105 0.0009 0.0014
Echinococcus granulosus tyrosine protein kinase Src64B 0.0516 0.1886 0.1883
Loa Loa (eye worm) AUR protein kinase 0.0327 0.1022 0.1109
Loa Loa (eye worm) hypothetical protein 0.0189 0.039 0.0423
Loa Loa (eye worm) TK/FER protein kinase 0.0234 0.0598 0.0649
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0516 0.1886 0.2282
Trichomonas vaginalis STE family protein kinase 0.0193 0.041 0.1672
Schistosoma mansoni serine/threonine protein kinase 0.0608 0.2305 0.3957
Entamoeba histolytica tyrosin kinase, putative 0.0112 0.0042 0.011
Trichomonas vaginalis AGC family protein kinase 0.014 0.0167 0.0658
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0201 0.0445 0.3977
Onchocerca volvulus 0.0129 0.0118 0.0208
Schistosoma mansoni tyrosine kinase 0.1012 0.4148 0.7125
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0129 0.0118 0.0195
Plasmodium falciparum serine/threonine protein kinase, putative 0.0327 0.1022 0.9235
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0179 0.0345 0.1456
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.019 0.0396 0.1143
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0187 0.038 0.1547
Trypanosoma cruzi casein kinase, putative 0.0244 0.0643 0.2762
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0516 0.1886 0.2282
Entamoeba histolytica protein kinase, putative 0.0187 0.038 0.1096
Trypanosoma brucei polo-like protein kinase 0.0608 0.2305 0.9564
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0113 0.0046 0.005
Loa Loa (eye worm) protein kinase domain-containing protein 0.0105 0.0009 0.001
Entamoeba histolytica tyrosine kinase, putative 0.0105 0.0009 0.0014
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0187 0.038 0.1618
Schistosoma mansoni rap gtpase-activating protein 0.0252 0.0678 0.1159
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0129 0.0118 0.0114
Loa Loa (eye worm) hypothetical protein 0.0188 0.0387 0.042
Entamoeba histolytica tyrosine kinase, putative 0.0105 0.0009 0.0014
Trichomonas vaginalis CAMK family protein kinase 0.0201 0.0445 0.1817
Schistosoma mansoni serine/threonine protein kinase 0.0362 0.1183 0.2027
Schistosoma mansoni serine/threonine protein kinase 0.0267 0.0748 0.1279
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0418 0.1437 0.1433
Schistosoma mansoni serine/threonine protein kinase 0.0302 0.091 0.1558
Echinococcus granulosus casein kinase I delta 0.0244 0.0643 0.0639
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0362 0.1183 0.118
Loa Loa (eye worm) hypothetical protein 0.0223 0.0548 0.0594
Schistosoma mansoni suppressor of cytokine signaling 0.0129 0.0118 0.0195
Trypanosoma cruzi casein kinase, putative 0.0244 0.0643 0.2762
Trichomonas vaginalis TK family protein kinase 0.0107 0.0015 0.0026
Entamoeba histolytica hypothetical protein 0.0105 0.0009 0.0014
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0047 0.016
Echinococcus multilocularis ephrin type A receptor 4 A 0.0249 0.0667 0.0804
Brugia malayi Immunoglobulin I-set domain containing protein 0.1428 0.6051 0.6564
Loa Loa (eye worm) hypothetical protein 0.0226 0.0563 0.0611
Loa Loa (eye worm) protein kinase domain-containing protein 0.034 0.1081 0.1174
Echinococcus multilocularis myotubularin protein 13 0.0114 0.0051 0.0057
Trypanosoma brucei Casein kinase II 0.0225 0.0555 0.2276
Echinococcus granulosus Vam6:Vps39 protein 0.0252 0.0678 0.0674
Echinococcus granulosus SH2 domain containing protein 7 0.0129 0.0118 0.0114
Loa Loa (eye worm) hypothetical protein 0.0129 0.0118 0.0128
Entamoeba histolytica protein kinase domain containing protein 0.0105 0.0009 0.0014
Entamoeba histolytica protein kinase, putative 0.0327 0.1022 0.2965
Echinococcus granulosus raf serine:threonine protein kinase 0.0199 0.0439 0.0435
Trichomonas vaginalis AGC family protein kinase 0.012 0.0075 0.0275
Entamoeba histolytica hypothetical protein 0.0275 0.0783 0.2269
Echinococcus granulosus mitogen activated protein kinase 14 0.0358 0.1162 0.1159
Trichomonas vaginalis conserved hypothetical protein 0.0107 0.0015 0.0026
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0226 0.0563 0.0559
Trypanosoma brucei Serine/threonine-protein kinase NEK11, putative 0.0114 0.0047 0.016
Echinococcus granulosus mitogen activated protein kinase 0.0129 0.0118 0.0114
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0129 0.0118 0.0138
Trypanosoma brucei protein kinase, putative 0.0179 0.0345 0.14
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0595 0.2244 0.2435
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0339 0.1077 0.1169
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0595 0.2244 0.2716
Loa Loa (eye worm) hypothetical protein 0.0436 0.152 0.1649
Entamoeba histolytica PH domain containing protein kinase, putative 0.0342 0.1092 0.3168
Schistosoma mansoni tyrosine kinase 0.0105 0.0009 0.0008
Trichomonas vaginalis CMGC family protein kinase 0.0312 0.0955 0.394
Entamoeba histolytica hypothetical protein 0.0105 0.0009 0.0014
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0129 0.0118 0.0473
Mycobacterium tuberculosis Probable oxidoreductase 0.0116 0.0058 1
Onchocerca volvulus 0.1094 0.4524 0.8652
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0125 0.0101 0.0097
Brugia malayi MAP kinase sur-1 0.0129 0.0118 0.0118
Schistosoma mansoni tensin-related 0.0129 0.0118 0.0195
Echinococcus granulosus tyrosine protein kinase csk 0.0105 0.0009 0.0005
Trichomonas vaginalis CAMK family protein kinase 0.0256 0.0699 0.2876
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0909 0.3679 0.3676
Echinococcus multilocularis 0.0344 0.1101 0.133
Entamoeba histolytica hypothetical protein 0.0106 0.0012 0.0023
Trypanosoma brucei SNF1-related protein kinases, putative 0.0201 0.0445 0.1817
Trichomonas vaginalis AGC family protein kinase 0.0631 0.241 1
Trichomonas vaginalis CAMK family protein kinase 0.0226 0.0563 0.2307
Trypanosoma brucei NIMA-related protein kinase 0.0114 0.0047 0.016
Entamoeba histolytica protein kinase, putative 0.0164 0.0279 0.0802
Loa Loa (eye worm) hypothetical protein 0.0144 0.0187 0.0203
Echinococcus multilocularis roundabout 2 0.0313 0.0959 0.1158
Plasmodium vivax glycogen synthase kinase 3, putative 0.0289 0.0849 0.7659
Schistosoma mansoni serine/threonine protein kinase 0.0312 0.0955 0.1635
Echinococcus multilocularis protein kinase 0.0105 0.0009 0.0006
Giardia lamblia Kinase, CMGC CDK 0.0267 0.0748 0.3217
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0226 0.0563 0.0559
Trypanosoma brucei casein kinase I, isoform 2 0.0244 0.0643 0.2642
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0226 0.0563 0.0611
Schistosoma mansoni tyrosine kinase 0.0516 0.1886 0.3236
Brugia malayi Temporarily assigned gene name protein 59 0.0291 0.0855 0.092
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0129 0.0118 0.0452
Trichomonas vaginalis AGC family protein kinase 0.0408 0.1393 0.5766
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0105 0.0009 0.0006
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0125 0.0101 0.0118

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 1 um PUBCHEM_BIOASSAY: qHTS Fluorescence Polarization Assay for Inhibitors of MLL CXXC domain - DNA interaction. (Class of assay: confirmatory) [Related pubchem assays: 2698 (Summary assay.)] ChEMBL. No reference
Potency (functional) 1.0418 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 5.0119 um PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins. (Class of assay: confirmatory) [Related pubchem assays: 1011 (Confirmation Concentration-Response Assay for Inhibitors of the Schistosoma mansoni Redox Cascade ), 448 (Schistosoma Mansoni Peroxiredoxins (Prx2) and thioredoxin glutathione reductase (TGR) coupled assay)] ChEMBL. No reference
Potency (functional) 13.1154 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 14.581 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 18.8876 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 20.5878 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493106, AID493143] ChEMBL. No reference
Potency (functional) 37.933 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: qHTS assay for re-activators of p53 using a Luc reporter. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504709] ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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