Detailed information for compound 1377414

Basic information

Technical information
  • TDR Targets ID: 1377414
  • Name: ethyl 5-(4-fluorophenyl)-1-[3-[(2-methoxyphen yl)methylamino]-3-oxopropyl]-2-methylpyrrole- 3-carboxylate
  • MW: 438.491 | Formula: C25H27FN2O4
  • H donors: 1 H acceptors: 2 LogP: 3.69 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)c1cc(n(c1C)CCC(=O)NCc1ccccc1OC)c1ccc(cc1)F
  • InChi: 1S/C25H27FN2O4/c1-4-32-25(30)21-15-22(18-9-11-20(26)12-10-18)28(17(21)2)14-13-24(29)27-16-19-7-5-6-8-23(19)31-3/h5-12,15H,4,13-14,16H2,1-3H3,(H,27,29)
  • InChiKey: AQACGANQAMEZAH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • ethyl 5-(4-fluorophenyl)-1-[3-[(2-methoxyphenyl)methylamino]-3-oxo-propyl]-2-methyl-pyrrole-3-carboxylate
  • 5-(4-fluorophenyl)-1-[3-[(2-methoxyphenyl)methylamino]-3-oxopropyl]-2-methyl-3-pyrrolecarboxylic acid ethyl ester
  • 5-(4-fluorophenyl)-1-[3-keto-3-[(2-methoxybenzyl)amino]propyl]-2-methyl-pyrrole-3-carboxylic acid ethyl ester
  • K906-3161
  • NCGC00140988-01

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens euchromatic histone-lysine N-methyltransferase 2 Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) pre-SET domain-containing protein family protein Get druggable targets OG5_131470 All targets in OG5_131470
Onchocerca volvulus Get druggable targets OG5_131470 All targets in OG5_131470
Brugia malayi Pre-SET motif family protein Get druggable targets OG5_131470 All targets in OG5_131470
Trichomonas vaginalis set domain proteins, putative Get druggable targets OG5_131470 All targets in OG5_131470
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) SH2 domain-containing protein 0.0055 0.0007 0.0007
Brugia malayi Protein kinase domain containing protein 0.011 0.0246 0.0246
Echinococcus multilocularis protein kinase shaggy 0.0288 0.103 0.2936
Brugia malayi Sex muscle abnormal protein 5 0.0095 0.0182 0.0181
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0263 0.0921 0.2229
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0736 0.2998 0.2998
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0099 0.0199 0.0476
Trichomonas vaginalis STE family protein kinase 0.0099 0.0199 0.1504
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0351 0.1306 0.1305
Brugia malayi SH2 domain containing protein 0.0055 0.0007 0.0007
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0095 0.0182 0.0181
Echinococcus granulosus tyrosine kinase 0.0194 0.0619 0.1495
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0277 0.098 0.2372
Echinococcus granulosus SH2 motif 0.0055 0.0007 0.0009
Plasmodium vivax protein kinase Crk2 0.0263 0.0921 0.7049
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0084 0.0135 0.0376
Trichomonas vaginalis CMGC family protein kinase 0.0351 0.1306 1
Trichomonas vaginalis AGC family protein kinase 0.0271 0.0955 0.7309
Loa Loa (eye worm) STAT protein 0.0055 0.0007 0.0007
Echinococcus granulosus nervana 2 0.0119 0.0289 0.0693
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0113 0.0262 0.1986
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0169 0.0509 0.0509
Echinococcus multilocularis SH2 motif 0.0055 0.0007 0.0011
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0263 0.0921 0.7049
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0056 0.0012 0.0068
Loa Loa (eye worm) TK/FER protein kinase 0.011 0.0246 0.0246
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0056 0.0012 0.0068
Loa Loa (eye worm) hypothetical protein 0.0062 0.0036 0.0036
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0095 0.0182 0.0181
Schistosoma mansoni tyrosine kinase 0.0246 0.0844 0.1601
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0146 0.0405 0.3085
Onchocerca volvulus 0.0055 0.0007 0.002
Brugia malayi Protein kinase domain containing protein 0.0054 0.0004 0.0003
Entamoeba histolytica protein kinase, putative 0.0292 0.1049 0.3491
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0233 0.0791 0.2252
Schistosoma mansoni tyrosine kinase 0.0442 0.1709 0.3242
Loa Loa (eye worm) TK protein kinase 0.0347 0.1289 0.1289
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0214 0.1614
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0263 0.0921 0.0921
Brugia malayi Temporarily assigned gene name protein 59 0.0124 0.0311 0.0311
Loa Loa (eye worm) hypothetical protein 0.0134 0.0353 0.0352
Brugia malayi serine/threonine kinase 12 0.0271 0.0955 0.0955
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0991 0.4121 1
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0102 0.0214 0.1612
Echinococcus multilocularis tyrosine protein kinase ABL1 0.031 0.1125 0.3209
Echinococcus multilocularis SH2 motif 0.0055 0.0007 0.0011
Schistosoma mansoni serine/threonine protein kinase 0.0249 0.0858 0.1627
Schistosoma mansoni tyrosine kinase 0.0254 0.0883 0.1674
Echinococcus multilocularis expressed protein 0.0096 0.0187 0.0525
Echinococcus granulosus dual specificity 0.015 0.0424 0.1021
Brugia malayi SH2 domain containing protein 0.011 0.0246 0.0246
Toxoplasma gondii CMGC kinase, CK2 family 0.0112 0.0259 0.1963
Giardia lamblia Kinase, CMGC SRPK 0.0096 0.0187 0.1409
Trichomonas vaginalis CAMK family protein kinase 0.0138 0.0371 0.2818
Entamoeba histolytica protein kinase, putative 0.0288 0.103 0.3428
Toxoplasma gondii AGC kinase 0.0284 0.1011 0.7739
Schistosoma mansoni serine/threonine protein kinase 0.0249 0.0858 0.1627
Onchocerca volvulus 0.0288 0.103 0.2943
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0113 0.0262 0.0628
Echinococcus multilocularis tensin 0.0055 0.0007 0.0011
Loa Loa (eye worm) TK/EPH protein kinase 0.0133 0.0349 0.0349
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0079 0.0111 0.0306
Echinococcus multilocularis dual specificity 0.0134 0.0353 0.0999
Plasmodium falciparum NIMA related kinase 4 0.0065 0.005 0.0355
Schistosoma mansoni serine/threonine protein kinase 0.0102 0.0214 0.0406
Loa Loa (eye worm) AUR protein kinase 0.0271 0.0955 0.0955
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0234 0.0793 0.2259
Schistosoma mansoni serine/threonine protein kinase 0.0271 0.0955 0.1812
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0234 0.0793 0.2259
Schistosoma mansoni hypothetical protein 0.0186 0.0581 0.1102
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0493 0.193 0.551
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0097 0.019 0.1429
Plasmodium vivax tyrosine kinase-like protein, putative 0.0094 0.0178 0.1341
Onchocerca volvulus 0.0055 0.0007 0.002
Schistosoma mansoni ephrin receptor 0.0116 0.0275 0.0522
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0271 0.0955 0.3178
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0113 0.0262 0.1986
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0225 0.0754 0.0754
Schistosoma mansoni serine/threonine protein kinase 0.0249 0.0858 0.1627
Entamoeba histolytica protein kinase domain containing protein 0.0112 0.0259 0.0853
Loa Loa (eye worm) TK/FER protein kinase 0.0054 0.0004 0.0003
Trichomonas vaginalis AGC family protein kinase 0.0292 0.1049 0.803
Brugia malayi Tyrosine-protein kinase abl-1 0.0226 0.0757 0.0756
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0134 0.0353 0.0353
Schistosoma mansoni serine/threonine protein kinase 0.0124 0.0311 0.0589
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0249 0.0858 0.6559
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.1253 0.5271 0.5271
Schistosoma mansoni serine/threonine kinase 0.0164 0.0487 0.0924
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0054 0.0004 0.0003
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.0029 0.0029
Schistosoma mansoni serine/threonine protein kinase 0.0083 0.0131 0.0248
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0149 0.0421 0.0798
Trichomonas vaginalis CAMK family protein kinase 0.0277 0.098 0.7501
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0214 0.1614
Schistosoma mansoni serine/threonine protein kinase 0.0321 0.1174 0.2226
Echinococcus multilocularis rac serine:threonine kinase 0.0176 0.0537 0.1524
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0127 0.0323 0.0775
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0113 0.0262 0.074
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0351 0.1306 1
Schistosoma mansoni serine/threonine protein kinase 0.0102 0.0214 0.0406
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0593 0.2369 0.2369
Entamoeba histolytica protein kinase, putative 0.0284 0.1011 0.3365
Onchocerca volvulus 0.0054 0.0004 0.0009
Loa Loa (eye worm) TK/FER protein kinase 0.0054 0.0004 0.0003
Trypanosoma brucei cdc2-related kinase 3 0.0263 0.0921 0.7049
Schistosoma mansoni tyrosine kinase 0.0054 0.0004 0.0007
Schistosoma mansoni protein kinase 0.0054 0.0004 0.0007
Echinococcus granulosus calcium activated potassium channel 0.0146 0.0406 0.0978
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0277 0.098 0.098
Giardia lamblia Kinase, CK1 Casein kinase 0.0121 0.0295 0.2241
Brugia malayi hypothetical protein 0.0055 0.0007 0.0007
Schistosoma mansoni tyrosine kinase 0.0054 0.0004 0.0007
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0096 0.0185 0.035
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0096 0.0187 0.0187
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0134 0.0353 0.2683
Brugia malayi Protein kinase domain containing protein 0.0193 0.0612 0.0612
Trypanosoma cruzi NIMA-related kinase, putative 0.0056 0.0012 0.0068
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0164 0.0487 0.1175
Loa Loa (eye worm) hypothetical protein 0.0079 0.011 0.011
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0073 0.0086 0.0629
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0121 0.0295 0.0295
Loa Loa (eye worm) SRC-1 0.0234 0.0793 0.0793
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0056 0.0012 0.0068
Trichomonas vaginalis CMGC family protein kinase 0.0288 0.103 0.7885
Brugia malayi Guanylyl cyclase protein 23 0.0054 0.0004 0.0003
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0201 0.0648 0.1565
Trichomonas vaginalis CK1 family protein kinase 0.0121 0.0295 0.2241
Entamoeba histolytica protein kinase , putative 0.0271 0.0955 0.3178
Echinococcus granulosus c src tyrosine kinase 0.0149 0.0421 0.1013
Brugia malayi Protein kinase domain containing protein 0.1303 0.5492 0.5492
Trichomonas vaginalis CMGC family protein kinase 0.0263 0.0921 0.7049
Schistosoma mansoni serine/threonine protein kinase 0.0164 0.0487 0.0924
Trypanosoma cruzi Serine/threonine-protein kinase NEK16, putative 0.0065 0.005 0.0355
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0134 0.0353 0.2683
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0098 0.0194 0.0635
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0056 0.0012 0.0068
Loa Loa (eye worm) AGC/PKA protein kinase 0.0249 0.0858 0.0857
Trichomonas vaginalis AGC family protein kinase 0.0292 0.1049 0.803
Schistosoma mansoni hypothetical protein 0.0055 0.0007 0.0014
Schistosoma mansoni growth factor receptor-bound protein 0.0097 0.019 0.0361
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0169 0.0509 0.3883
Echinococcus granulosus casein kinase I alpha 0.0121 0.0295 0.0709
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0321 0.1174 0.3346
Entamoeba histolytica casein kinase 1, putative 0.0121 0.0295 0.0974
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0214 0.1614
Loa Loa (eye worm) hypothetical protein 0.0079 0.0111 0.011
Echinococcus granulosus Glutaredoxin protein 5 0.0119 0.0289 0.0693
Echinococcus multilocularis rho associated protein kinase 0.0781 0.3197 0.9134
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0146 0.0405 0.1149
Schistosoma mansoni GTPase activating protein 0.0055 0.0007 0.0014
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0214 0.1614
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0249 0.0858 0.2443
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0056 0.0012 0.0068
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0169 0.0509 0.3883
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0095 0.018 0.0429
Schistosoma mansoni protein kinase 0.0099 0.0199 0.0378
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0249 0.0858 0.6559
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0012 0.0068
Brugia malayi STAT protein, DNA binding domain containing protein 0.0055 0.0007 0.0007
Giardia lamblia Kinase, CMGC GSK 0.0288 0.103 0.7885
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0055 0.0007 0.0011
Echinococcus granulosus mitogen activated protein kinase 3 0.0097 0.019 0.0452
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.015 0.0424 0.3228
Loa Loa (eye worm) TK protein kinase 0.0286 0.102 0.1019
Trichomonas vaginalis CMGC family protein kinase 0.0112 0.0259 0.1963
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0249 0.0858 0.6559
Loa Loa (eye worm) hypothetical protein 0.0186 0.0581 0.0581
Trypanosoma cruzi aurora B kinase, putative 0.0271 0.0955 0.7309
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0113 0.0262 0.1986
Brugia malayi Casein kinase II, alpha chain 0.0112 0.0259 0.0259
Giardia lamblia Kinase, AGC AKT 0.0129 0.0331 0.2515
Trichomonas vaginalis STE family protein kinase 0.0099 0.0199 0.1504
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0012 0.0068
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0263 0.0921 0.7049
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0096 0.0185 0.0184
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.085 0.35 0.8492
Trichomonas vaginalis CAMK family protein kinase 0.0277 0.098 0.7501
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0054 0.0004 0.0003
Brugia malayi Immunoglobulin I-set domain containing protein 0.0094 0.0177 0.0177
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0249 0.0858 0.6559
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0736 0.2998 0.7274
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0234 0.0793 0.2259
Schistosoma mansoni serine/threonine protein kinase 0.015 0.0424 0.0804
Brugia malayi Protein kinase domain containing protein 0.0292 0.1049 0.1049
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.023 0.0777 0.0776
Plasmodium falciparum calcium-dependent protein kinase 2 0.0113 0.0262 0.1986
Loa Loa (eye worm) TK/INSR protein kinase 0.0442 0.1709 0.1709
Echinococcus granulosus nervana 2 0.0119 0.0289 0.0693
Loa Loa (eye worm) TK/FER protein kinase 0.0054 0.0004 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0146 0.0406 0.0771
Plasmodium vivax serine/threonine-protein kinase Nek1, putative 0.0065 0.005 0.0355
Echinococcus multilocularis dual specificity 0.015 0.0424 0.1202
Schistosoma mansoni tyrosine kinase 0.0234 0.0793 0.1505
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0142 0.0389 0.1101
Loa Loa (eye worm) SH2 domain-containing protein 0.0055 0.0007 0.0007
Brugia malayi Protein kinase domain containing protein 0.0594 0.2378 0.2377
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0102 0.0214 0.1612
Schistosoma mansoni protein kinase 0.0054 0.0004 0.0007
Echinococcus granulosus roundabout 2 0.0131 0.0342 0.0822
Brugia malayi MH2 domain containing protein 0.0136 0.0362 0.0362
Onchocerca volvulus 0.0054 0.0004 0.0009
Plasmodium falciparum casein kinase 2, alpha subunit 0.0112 0.0259 0.1963
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0056 0.0012 0.0068
Echinococcus multilocularis serine threonine protein kinase 0.0204 0.0661 0.1879
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0246 0.0844 0.2403
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.0187 0.0355
Plasmodium falciparum cGMP-dependent protein kinase 0.0146 0.0405 0.3085
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0249 0.0858 0.2443
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0249 0.0858 0.2074
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0012 0.0068
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0201 0.0648 0.1843
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0012 0.0068
Echinococcus multilocularis serine:threonine protein kinase 0.0126 0.0319 0.0901
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0102 0.0214 0.1614
Giardia lamblia Kinase, NEK 0.0147 0.0412 0.3135
Leishmania major serine/threonine-protein kinase a, putative 0.0056 0.0012 0.0068
Brugia malayi Tyrosine-protein kinase abl-1 0.0124 0.0308 0.0307
Echinococcus multilocularis hypothetical protein 0.0098 0.0197 0.0552
Plasmodium falciparum calcium-dependent protein kinase 1 0.0113 0.0262 0.1986
Schistosoma mansoni protein kinase 0.0349 0.13 0.2466
Echinococcus granulosus expressed conserved protein 0.0055 0.0007 0.0009
Loa Loa (eye worm) hypothetical protein 0.0086 0.0143 0.0143
Brugia malayi Protein kinase domain containing protein 0.0174 0.053 0.053
Onchocerca volvulus 0.011 0.0246 0.0703
Onchocerca volvulus Tyrosine kinase homolog 0.0517 0.2038 0.5824
Echinococcus multilocularis twitchin 0.0068 0.0065 0.0174
Brugia malayi cell division control protein 2 homolog 0.0263 0.0921 0.0921
Schistosoma mansoni protein kinase 0.0078 0.0108 0.0204
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0224 0.075 0.2136
Trichomonas vaginalis CMGC family protein kinase 0.0263 0.0921 0.7049
Loa Loa (eye worm) AUR protein kinase 0.0271 0.0955 0.0955
Trichomonas vaginalis CMGC family protein kinase 0.0112 0.0259 0.1963
Loa Loa (eye worm) hypothetical protein 0.0054 0.0004 0.0003
Echinococcus multilocularis casein kinase I alpha 0.0121 0.0295 0.0834
Schistosoma mansoni SH2A 0.0055 0.0007 0.0014
Trichomonas vaginalis AGC family protein kinase 0.0271 0.0955 0.7309
Entamoeba histolytica protein kinase, putative 0.0056 0.0012 0.0029
Loa Loa (eye worm) CDC7 protein kinase 0.0278 0.0987 0.0987
Plasmodium falciparum serine/threonine protein kinase KIN 0.0102 0.0214 0.1614
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0113 0.0262 0.0262
Schistosoma mansoni ste20-related kinase 0.0214 0.0704 0.1336
Loa Loa (eye worm) hypothetical protein 0.0055 0.0007 0.0007
Echinococcus granulosus tyrosine protein kinase Src64B 0.0234 0.0793 0.1918
Echinococcus granulosus tyrosine protein kinase HCK 0.0139 0.0376 0.0905
Loa Loa (eye worm) MH2 domain-containing protein 0.0136 0.0362 0.0362
Loa Loa (eye worm) hypothetical protein 0.0094 0.0177 0.0177
Schistosoma mansoni serine/threonine protein kinase 0.0224 0.075 0.1423
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0146 0.0405 0.1149
Echinococcus granulosus SHC transforming protein 3 0.0055 0.0007 0.0009
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0245 0.0844 0.0843
Echinococcus granulosus cyclin dependent kinase 5 0.0263 0.0921 0.2229
Entamoeba histolytica protein kinase, putative 0.0271 0.0955 0.3178
Onchocerca volvulus 0.011 0.0246 0.0703
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0004 0.0007
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0054 0.0004 0.0003
Trypanosoma cruzi p21-activated kinase 3, putative 0.0069 0.0067 0.0483
Leishmania major protein kinase, putative 0.0056 0.0012 0.0068
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0055 0.0007 0.0009
Echinococcus granulosus Vam6:Vps39 protein 0.0186 0.0581 0.1402
Echinococcus granulosus serine:threonine protein kinase N2 0.0125 0.0314 0.0754
Brugia malayi Protein kinase domain containing protein 0.0054 0.0004 0.0003
Schistosoma mansoni protein kinase 0.0252 0.0872 0.1655
Echinococcus multilocularis mitogen activated protein kinase 11 0.0169 0.0509 0.1446
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0012 0.0068
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0249 0.0858 0.6559
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0055 0.0007 0.0011
Schistosoma mansoni serine/threonine protein kinase 0.0134 0.0353 0.067
Echinococcus granulosus casein kinase i 0.0121 0.0295 0.0709
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0012 0.0068
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0284 0.1011 0.1011
Brugia malayi hypothetical protein 0.0054 0.0004 0.0004
Brugia malayi putative serine/threonine kinase SADA gamma 0.0102 0.0214 0.0213
Schistosoma mansoni protein kinase 0.0054 0.0004 0.0007
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0055 0.0007 0.002
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0094 0.0178 0.1341
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0288 0.103 0.7885
Loa Loa (eye worm) TK protein kinase 0.0266 0.0934 0.0934
Echinococcus granulosus tyrosine protein kinase Src42A 0.0142 0.0389 0.0935
Loa Loa (eye worm) TK/RYK protein kinase 0.0054 0.0004 0.0003
Toxoplasma gondii AGC kinase 0.0249 0.0858 0.6559
Onchocerca volvulus 0.0054 0.0004 0.0009
Echinococcus multilocularis SH2 motif 0.0055 0.0007 0.0011
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0113 0.0262 0.1986
Trichomonas vaginalis CAMK family protein kinase 0.0065 0.005 0.0355
Trypanosoma cruzi NIMA-related kinase, putative 0.0056 0.0012 0.0068
Schistosoma mansoni tyrosine kinase 0.0149 0.0421 0.0798
Trichomonas vaginalis CAMK family protein kinase 0.0065 0.005 0.0355
Schistosoma mansoni nephrin 0.0114 0.0267 0.0506
Giardia lamblia Kinase, CMGC CK2 0.0112 0.0259 0.1963
Echinococcus multilocularis ephrin type A receptor 4 A 0.0116 0.0275 0.0776
Schistosoma mansoni signal transduction protein lnk-related 0.0055 0.0007 0.0014
Schistosoma mansoni serine/threonine protein kinase 0.0244 0.0838 0.1589
Onchocerca volvulus 0.011 0.0246 0.0703
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0129 0.0331 0.0331
Trichomonas vaginalis CMGC family protein kinase 0.015 0.0424 0.3228
Schistosoma mansoni serine/threonine protein kinase 0.0263 0.0921 0.1748
Onchocerca volvulus 0.0054 0.0004 0.0009
Toxoplasma gondii protein kinase domain-containing protein 0.0056 0.0012 0.0068
Loa Loa (eye worm) TK protein kinase 0.0194 0.0619 0.0619
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0079 0.0111 0.021
Schistosoma mansoni protein kinase 0.0121 0.0295 0.056
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0214 0.1614
Entamoeba histolytica protein kinase domain containing protein 0.0057 0.0017 0.0045
Echinococcus granulosus cGMP dependent protein kinase 1 0.0146 0.0405 0.0976
Trypanosoma brucei protein kinase, putative 0.0056 0.0012 0.0068
Brugia malayi Tensin 0.0055 0.0007 0.0007
Echinococcus granulosus SH2 domain containing adapter protein F 0.0055 0.0007 0.0009
Brugia malayi probable protein kinase 0.0535 0.2116 0.2116
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0736 0.2998 0.8566
Leishmania major protein kinase, putative 0.0351 0.1306 1
Schistosoma mansoni tyrosine kinase 0.0054 0.0004 0.0007
Giardia lamblia Kinase, AGC PKA 0.0167 0.0499 0.3802
Trypanosoma cruzi cdc2-related kinase 1 0.0263 0.0921 0.7049
Brugia malayi integrin-linked kinase 0.0054 0.0004 0.0003
Brugia malayi hypothetical protein 0.0186 0.0581 0.0581
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0096 0.0187 0.1409
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0263 0.0921 0.0921
Echinococcus multilocularis dual specificity protein kinase clk2 0.0351 0.1306 0.3724
Giardia lamblia Protein 21.1 0.0054 0.0004 0.000000050977
Plasmodium falciparum calcium-dependent protein kinase 5 0.0113 0.0262 0.1986
Brugia malayi Protein kinase domain containing protein 0.011 0.0246 0.0246
Schistosoma mansoni serine/threonine protein kinase 0.0244 0.0838 0.1589
Toxoplasma gondii histone kinase SNF1, putative 0.0102 0.0214 0.1614
Loa Loa (eye worm) hypothetical protein 0.0054 0.0004 0.0004
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0493 0.193 0.4679
Schistosoma mansoni serine/threonine RGC 0.0054 0.0004 0.0007
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0012 0.0068
Entamoeba histolytica serine/threonine protein kinase, putative 0.0277 0.098 0.3261
Schistosoma mansoni tyrosine kinase 0.0369 0.1385 0.2628
Loa Loa (eye worm) CAMK/PIM protein kinase 0.085 0.35 0.3499
Echinococcus multilocularis casein kinase I alpha 0.0121 0.0295 0.0834
Loa Loa (eye worm) hypothetical protein 0.011 0.0246 0.0246
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0055 0.0007 0.0009
Toxoplasma gondii NEK kinase 0.0065 0.005 0.0355
Trypanosoma brucei aurora B kinase 0.0271 0.0955 0.7309
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0406 0.1551 0.3759
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.01 0.0206 0.0206
Brugia malayi Raf kinase 0.0054 0.0004 0.0003
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0113 0.0262 0.0628
Schistosoma mansoni hypothetical protein 0.0098 0.0197 0.0373
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0186 0.0581 0.1102
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0056 0.0012 0.0068
Leishmania major protein kinase, putative 0.0113 0.0262 0.1986
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0226 0.0757 0.0757
Trichomonas vaginalis STE family protein kinase 0.0099 0.0199 0.1504
Entamoeba histolytica protein kinase, putative 0.0164 0.0487 0.1615
Entamoeba histolytica protein kinase, putative 0.0103 0.0217 0.0714
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0056 0.0012 0.0068
Schistosoma mansoni tyrosine kinase 0.0054 0.0004 0.0007
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0233 0.0791 0.1912
Schistosoma mansoni tyrosine kinase 0.0315 0.1151 0.2184
Echinococcus multilocularis death associated protein kinase 1 0.0834 0.343 0.9801
Entamoeba histolytica SH2-protein kinase domain containing protein 0.011 0.0246 0.0811
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0054 0.0004 0.0003
Plasmodium vivax serine/threonine kinase-1, putative 0.0351 0.1306 1
Brugia malayi SH2 domain containing protein 0.0055 0.0007 0.0007
Echinococcus multilocularis mitogen activated protein kinase 11 0.0169 0.0509 0.1446
Brugia malayi STE20-like kinase MST 0.0264 0.0923 0.0923
Brugia malayi protein-tyrosine kinase 0.0194 0.0619 0.0619
Entamoeba histolytica hypothetical protein 0.0134 0.0353 0.1166
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0012 0.0068
Echinococcus granulosus casein kinase ii subunit alpha 0.0112 0.0259 0.0621
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0161 0.0474 0.0474
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0112 0.0259 0.1963
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0487 0.3714
Trichomonas vaginalis AGC family protein kinase 0.0292 0.1049 0.803
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0448 0.1732 0.1732
Onchocerca volvulus 0.0054 0.0004 0.0009
Loa Loa (eye worm) hypothetical protein 0.0098 0.0197 0.0196
Loa Loa (eye worm) TK/ACK protein kinase 0.0054 0.0004 0.0003
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0012 0.0068
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0351 0.1306 1
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0252 0.0872 0.211
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0234 0.0793 0.2259
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.015 0.0424 0.0424
Entamoeba histolytica protein kinase domain containing protein 0.0271 0.0955 0.3178
Schistosoma mansoni serine/threonine protein kinase 0.085 0.35 0.6639
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0167 0.0499 0.3802
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0098 0.0194 0.1459
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0098 0.0194 0.1459
Schistosoma mansoni tyrosine kinase 0.0054 0.0004 0.0007
Brugia malayi Stress-activated protein kinase jnk-1 0.0271 0.0955 0.0954
Loa Loa (eye worm) TK/FER protein kinase 0.011 0.0246 0.0246
Schistosoma mansoni serine/threonine protein kinase 0.0781 0.3197 0.6065
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0095 0.018 0.018
Trypanosoma cruzi casein kinase II, putative 0.0112 0.0259 0.1963
Entamoeba histolytica protein kinase, putative 0.0292 0.1049 0.3491
Trichomonas vaginalis CMGC family protein kinase 0.015 0.0424 0.3228
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0004 0.0007
Loa Loa (eye worm) thyroid receptor interactor 0.0113 0.026 0.026
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0434 0.1674 0.4777
Leishmania major protein kinase, putative 0.0351 0.1306 1
Entamoeba histolytica protein kinase, putative 0.0087 0.0145 0.0473
Giardia lamblia Kinase, PLK 0.0277 0.098 0.7501
Schistosoma mansoni serine/threonine protein kinase 0.0121 0.0295 0.056
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0055 0.0007 0.0011
Entamoeba histolytica protein kinase, putative 0.0096 0.0187 0.0613
Onchocerca volvulus 0.0178 0.0547 0.1563
Schistosoma mansoni tensin-related 0.0055 0.0007 0.0014
Echinococcus granulosus cGMP dependent protein kinase 1 0.0146 0.0405 0.0976
Toxoplasma gondii AGC kinase 0.0249 0.0858 0.6559
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0457 0.1776 0.5068
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0012 0.0068
Brugia malayi Protein kinase domain containing protein 0.0203 0.0656 0.0656
Trichomonas vaginalis CMGC family protein kinase 0.0263 0.0921 0.7049
Schistosoma mansoni serine/threonine protein kinase 0.0146 0.0405 0.0769
Schistosoma mansoni tyrosine kinase 0.0344 0.1277 0.2423
Loa Loa (eye worm) RGC/RGC protein kinase 0.0054 0.0004 0.0003
Loa Loa (eye worm) TK/FER protein kinase 0.0402 0.1532 0.1532
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0271 0.0955 0.3178
Brugia malayi serine/threonine-protein kinase PAK 7 0.024 0.0818 0.0818
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0055 0.0007 0.0011
Brugia malayi Protein kinase domain containing protein 0.0054 0.0004 0.0003
Plasmodium falciparum calcium-dependent protein kinase 4 0.0113 0.0262 0.1986
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0406 0.1551 0.4426
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0054 0.0004 0.0003
Echinococcus multilocularis raf serine:threonine protein kinase 0.0095 0.0181 0.0507
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0119 0.0289 0.0816
Echinococcus multilocularis Immunoglobulin 0.0079 0.0111 0.0306
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0054 0.0004 0.0003
Onchocerca volvulus 0.0055 0.0007 0.002
Trichomonas vaginalis CMGC family protein kinase 0.0112 0.0259 0.1963
Echinococcus granulosus defective proboscis extension response 0.0079 0.0111 0.026
Trichomonas vaginalis CMGC family protein kinase 0.015 0.0424 0.3228
Brugia malayi Protein kinase domain containing protein 0.0548 0.2174 0.2174
Onchocerca volvulus 0.0138 0.037 0.1056
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0185 0.058 0.058
Trypanosoma brucei NIMA-related protein kinase 0.0065 0.005 0.0355
Brugia malayi Protein kinase domain containing protein 0.0054 0.0004 0.0003
Entamoeba histolytica protein kinase domain containing protein 0.0288 0.103 0.3428
Brugia malayi protein unc-22 0.0083 0.0131 0.0131
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0113 0.0262 0.1986
Entamoeba histolytica protein kinase, putative 0.0054 0.0004 0.000000022164
Brugia malayi SRC-1 0.0234 0.0793 0.0793
Entamoeba histolytica protein kinase domain containing protein 0.0102 0.0214 0.0701
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0054 0.0004 0.0009
Echinococcus multilocularis insulin receptor 0.0442 0.1709 0.4879
Trypanosoma cruzi Protein kinase B 0.0176 0.0537 0.4093
Echinococcus multilocularis mitogen activated protein kinase 3 0.0097 0.019 0.0532
Echinococcus granulosus serine:threonine kinase SAD 1 0.0102 0.0214 0.051
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0167 0.0499 0.1416
Echinococcus multilocularis nervana 2 0.0119 0.0289 0.0816
Echinococcus multilocularis calcium activated potassium channel 0.0146 0.0406 0.1152
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0457 0.1776 0.4304
Brugia malayi Doublecortin family protein 0.0161 0.0474 0.0474
Echinococcus multilocularis 0.0167 0.0501 0.1422
Trichomonas vaginalis CMGC family protein kinase 0.0097 0.019 0.1429
Trichomonas vaginalis STE family protein kinase 0.0065 0.005 0.0355
Loa Loa (eye worm) TK/FAK protein kinase 0.0548 0.2174 0.2174
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0349 0.13 0.13
Schistosoma mansoni tensin-related 0.0055 0.0007 0.0014
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0054 0.0004 0.0007
Echinococcus granulosus serine/threonine protein kinase 0.0176 0.0537 0.1294
Onchocerca volvulus 0.0134 0.0353 0.1007
Echinococcus multilocularis SHC transforming protein 3 0.0055 0.0007 0.0011
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0127 0.0323 0.0912
Loa Loa (eye worm) hypothetical protein 0.0138 0.0373 0.0373
Entamoeba histolytica protein kinase, putative 0.0055 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0055 0.0007 0.0007
Echinococcus granulosus expressed protein 0.0096 0.0187 0.0446
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0214 0.1614
Schistosoma mansoni tensin 0.0055 0.0007 0.0014
Schistosoma mansoni rap gtpase-activating protein 0.0186 0.0581 0.1102
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0102 0.0214 0.1614
Onchocerca volvulus 0.011 0.0246 0.0703
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0288 0.103 0.1954
Trichomonas vaginalis TKL family protein kinase 0.0054 0.0004 0.000000050977
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0263 0.0921 0.7049
Entamoeba histolytica hypothetical protein 0.0055 0.0005 0.0004
Trypanosoma brucei Serine/threonine-protein kinase NEK16, putative 0.0065 0.005 0.0355
Echinococcus granulosus cyclin dependent kinase 1 0.0263 0.0921 0.2229
Schistosoma mansoni serine/threonine protein kinase 0.0146 0.0406 0.0771
Echinococcus granulosus suppressor of cytokine signaling 7 0.0055 0.0007 0.0009
Trichomonas vaginalis CMGC family protein kinase 0.0112 0.0259 0.1963
Echinococcus multilocularis tyrosine protein kinase shark 0.0315 0.1151 0.3283
Schistosoma mansoni hypothetical protein 0.0054 0.0004 0.0007
Schistosoma mansoni serine/threonine-protein kinase 0.0176 0.0537 0.1018
Brugia malayi SH2 domain containing protein 0.0055 0.0007 0.0007
Loa Loa (eye worm) TK/ALK protein kinase 0.0282 0.1006 0.1006
Brugia malayi SH2 domain containing protein 0.0055 0.0007 0.0007
Trichomonas vaginalis AGC family protein kinase 0.0292 0.1049 0.803
Brugia malayi Protein kinase domain containing protein 0.0096 0.0187 0.0187
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.023 0.0777 0.2211
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0195 0.0622 0.0622
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.015 0.0424 0.3228
Giardia lamblia Kinase, CMGC DYRK 0.015 0.0424 0.3228
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0012 0.0068
Entamoeba histolytica PH domain containing protein kinase, putative 0.0056 0.0012 0.0029
Brugia malayi Variant SH3 domain containing protein 0.0095 0.0182 0.0181
Loa Loa (eye worm) RGC/RGC protein kinase 0.0054 0.0004 0.0003
Schistosoma mansoni suppressor of cytokine signaling 0.0055 0.0007 0.0014
Echinococcus granulosus cyclin dependent kinase 0.0263 0.0921 0.2229
Onchocerca volvulus 0.0073 0.0086 0.0243
Brugia malayi p70 ribosomal S6 kinase beta 0.0284 0.1011 0.1011
Onchocerca volvulus Serine\/threonine kinase homolog 0.0174 0.053 0.1514
Trypanosoma cruzi casein kinase, putative 0.0121 0.0295 0.2241
Schistosoma mansoni cell adhesion molecule 0.0111 0.0252 0.0478
Trichomonas vaginalis CMGC family protein kinase 0.0112 0.0259 0.1963
Plasmodium falciparum NIMA related kinase 1 0.0147 0.0412 0.3135
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0202 0.0652 0.0652
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0195 0.0622 0.0622
Echinococcus granulosus mitogen activated protein kinase 11 0.0169 0.0509 0.1228
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0094 0.0178 0.1341
Loa Loa (eye worm) hypothetical protein 0.0055 0.0007 0.0007
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0083 0.0131 0.0131
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0214 0.1614
Loa Loa (eye worm) hypothetical protein 0.0348 0.1293 0.1293
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0112 0.0259 0.0259
Schistosoma mansoni serine/threonine protein kinase 0.0245 0.0844 0.16
Brugia malayi Protein kinase domain containing protein 0.0054 0.0004 0.0003
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0487 0.1907 0.4622
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0069 0.0067 0.0483
Echinococcus granulosus calcium dependent protein kinase 0.0065 0.0052 0.0118
Schistosoma mansoni tyrosine protein kinase 0.0054 0.0004 0.0007
Echinococcus multilocularis expressed conserved protein 0.0146 0.0405 0.1149
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0736 0.2998 0.2998
Loa Loa (eye worm) SH2 domain-containing protein 0.0055 0.0007 0.0007
Brugia malayi cytokine inducible SH2-containing protein 5 0.0055 0.0007 0.0007
Schistosoma mansoni ephrin receptor 0.0069 0.007 0.0133
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0054 0.0004 0.0003
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0054 0.0004 0.0007
Echinococcus multilocularis tyrosine protein kinase Srms 0.0194 0.0619 0.1761
Schistosoma mansoni atypical protein kinase C 0.029 0.1042 0.1976
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0244 0.0838 0.2386
Mycobacterium tuberculosis Possible penicillin-binding protein 0.027 0.095 0.5
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0234 0.0793 0.1918
Loa Loa (eye worm) AGC/AKT protein kinase 0.0292 0.1049 0.1049
Echinococcus granulosus NCK adaptor protein 0.0095 0.0182 0.0432
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0065 0.0051 0.005
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0012 0.0068
Loa Loa (eye worm) hypothetical protein 0.0055 0.0007 0.0007
Trichomonas vaginalis CMGC family protein kinase 0.0112 0.0259 0.1963
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0054 0.0004 0.0003
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0164 0.0487 0.1383
Leishmania major protein kinase A catalytic subunit 0.0249 0.0858 0.6559
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0055 0.0007 0.0007
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0056 0.0012 0.0021
Loa Loa (eye worm) hypothetical protein 0.0054 0.0004 0.0003
Brugia malayi Serine/threonine-protein kinase SULU 0.023 0.0777 0.0776
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0098 0.0194 0.1459
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.0029 0.0029
Trichomonas vaginalis CAMK family protein kinase 0.0126 0.0319 0.2418
Brugia malayi hypothetical protein 0.0054 0.0004 0.0003
Brugia malayi Protein kinase domain containing protein 0.011 0.0246 0.0246
Echinococcus multilocularis casein kinase ii subunit alpha 0.0112 0.0259 0.0731
Schistosoma mansoni tyrosine kinase 0.0234 0.0793 0.1505
Trypanosoma cruzi casein kinase, putative 0.0121 0.0295 0.2241
Brugia malayi Protein kinase domain containing protein 0.1253 0.5271 0.5271
Onchocerca volvulus 0.0055 0.0007 0.002
Brugia malayi Protein kinase domain containing protein 0.0054 0.0004 0.0003
Brugia malayi casein kinase I 0.0121 0.0295 0.0295
Entamoeba histolytica PH domain containing protein kinase, putative 0.0257 0.0896 0.2978
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0102 0.0214 0.1614
Schistosoma mansoni serine/threonine protein kinase 0.0065 0.005 0.0095
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0121 0.0295 0.0295
Brugia malayi Protein kinase domain containing protein 0.0263 0.0921 0.0921
Entamoeba histolytica PH domain containing protein kinase, putative 0.0176 0.0537 0.178
Schistosoma mansoni tyrosine kinase 0.026 0.0908 0.1723
Schistosoma mansoni protein kinase 0.0099 0.0199 0.0378
Echinococcus multilocularis dual specificity 0.015 0.0424 0.1202
Onchocerca volvulus 0.0062 0.0036 0.0102
Plasmodium falciparum serine/threonine protein kinase 0.0096 0.0187 0.1409
Loa Loa (eye worm) hypothetical protein 0.0054 0.0004 0.0003
Trichomonas vaginalis CAMK family protein kinase 0.0127 0.0323 0.245
Brugia malayi Variant SH3 domain containing protein 0.0096 0.0185 0.0184
Brugia malayi Protein kinase domain containing protein 0.0054 0.0004 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0321 0.1174 0.2226
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0096 0.0186 0.0442
Onchocerca volvulus 0.0278 0.0987 0.2819
Echinococcus granulosus mitogen activated protein kinase 0.0097 0.019 0.0452
Brugia malayi RhoGAP domain containing protein 0.0096 0.0185 0.0184
Plasmodium vivax casein kinase 1, putative 0.0121 0.0295 0.2241
Trichomonas vaginalis AGC family protein kinase 0.0095 0.018 0.1356
Giardia lamblia Kinase, NEK 0.0065 0.005 0.0355
Brugia malayi C1-like domain containing protein 0.0226 0.0757 0.0757
Echinococcus multilocularis epidermal growth factor receptor 0.0599 0.2398 0.6849
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0056 0.0012 0.0024
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0214 0.1614
Loa Loa (eye worm) hypothetical protein 0.0079 0.0111 0.011
Echinococcus granulosus tyrosine protein kinase shark 0.0315 0.1151 0.2787
Brugia malayi Protein kinase domain containing protein 0.0054 0.0004 0.0003
Echinococcus multilocularis CDC7 cell division cycle 7 0.0278 0.0987 0.2812
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0097 0.019 0.1429
Plasmodium falciparum calcium-dependent protein kinase 3 0.0113 0.0262 0.1986
Trichomonas vaginalis CMGC family protein kinase 0.0097 0.019 0.1429
Brugia malayi Protein kinase domain containing protein 0.0225 0.0754 0.0754
Echinococcus granulosus tyrosine protein kinase Lyn 0.0282 0.1003 0.2428
Loa Loa (eye worm) TK protein kinase 0.0054 0.0004 0.0003
Schistosoma mansoni tyrosine kinase 0.0344 0.1277 0.2423
Trichomonas vaginalis CAMK family protein kinase 0.0277 0.098 0.7501
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0012 0.0068
Loa Loa (eye worm) TK/ROR protein kinase 0.0075 0.0094 0.0093
Loa Loa (eye worm) hypothetical protein 0.0116 0.0276 0.0275
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0065 0.005 0.0355
Brugia malayi Protein kinase domain containing protein 0.0054 0.0004 0.0003
Echinococcus granulosus tyrosine protein kinase Fyn 0.0234 0.0793 0.1918
Echinococcus granulosus serine threonine protein kinase nrc 0.0167 0.0499 0.1202
Trypanosoma cruzi NIMA-related kinase, putative 0.0065 0.005 0.0355
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0234 0.0793 0.2259
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0246 0.0844 0.2403
Schistosoma mansoni tensin 0.0055 0.0007 0.0014
Loa Loa (eye worm) RGC/RGC protein kinase 0.0054 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0116 0.0276 0.0275
Loa Loa (eye worm) hypothetical protein 0.0055 0.0007 0.0007
Brugia malayi Protein kinase domain containing protein 0.0054 0.0004 0.0003
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0195 0.0622 0.1503
Loa Loa (eye worm) hypothetical protein 0.0079 0.0112 0.0111
Mycobacterium ulcerans hypothetical protein 0.0098 0.0195 0.5
Schistosoma mansoni protein kinase 0.0448 0.1732 0.3286
Echinococcus multilocularis cyclin dependent kinase 0.0263 0.0921 0.2625
Entamoeba histolytica protein kinase, putative 0.0096 0.0187 0.0613
Echinococcus multilocularis SH2 domain containing protein 7 0.0055 0.0007 0.0011
Entamoeba histolytica hypothetical protein 0.0055 0.0005 0.0004
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0097 0.019 0.1429
Brugia malayi SH2 domain containing protein 0.0055 0.0007 0.0007
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0277 0.098 0.7501
Echinococcus multilocularis casein kinase I delta 0.0121 0.0295 0.0834
Brugia malayi Protein kinase domain containing protein 0.0054 0.0004 0.0003
Brugia malayi tRNA modification GTPase TrmE family protein 0.0055 0.0007 0.0007
Trichomonas vaginalis CMGC family protein kinase 0.015 0.0424 0.3228
Schistosoma mansoni serine/threonine protein kinase 0.0146 0.0406 0.0771
Schistosoma mansoni serine/threonine protein kinase 0.1253 0.5271 1
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0055 0.0007 0.0011
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0099 0.0199 0.0476
Brugia malayi Fes/CIP4 homology domain containing protein 0.0113 0.026 0.026
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0117 0.0277 0.2102
Echinococcus granulosus protein kinase C gamma type 0.0204 0.0661 0.1596
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0054 0.0004 0.0007
Loa Loa (eye worm) TK protein kinase 0.0054 0.0004 0.0003
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0186 0.0581 0.1102
Onchocerca volvulus 0.0781 0.3197 0.9135
Echinococcus multilocularis tyrosine protein kinase 0.0286 0.102 0.2906
Loa Loa (eye worm) hypothetical protein 0.0348 0.1293 0.1293
Brugia malayi Immunoglobulin I-set domain containing protein 0.0593 0.2369 0.2369
Plasmodium falciparum casein kinase 1 0.0121 0.0295 0.2241
Trypanosoma cruzi cdc2-related kinase 3 0.0263 0.0921 0.7049
Onchocerca volvulus 0.0286 0.1022 0.292
Loa Loa (eye worm) hypothetical protein 0.0445 0.172 0.172
Trypanosoma cruzi casein kinase, putative 0.0121 0.0295 0.2241
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0249 0.0858 0.6559
Echinococcus granulosus neuroglian 0.0099 0.0201 0.0478
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0249 0.0858 0.6559
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0121 0.0295 0.0295
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0396 0.1505 0.3648
Schistosoma mansoni serine/threonine protein kinase 0.0396 0.1505 0.2856
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0096 0.0187 0.1409
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0102 0.0214 0.1614
Echinococcus multilocularis N chimaerin 0.0096 0.0185 0.0518
Trichomonas vaginalis CAMK family protein kinase 0.0127 0.0323 0.245
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0251 0.0869 0.0869
Loa Loa (eye worm) TK/FER protein kinase 0.011 0.0246 0.0246
Entamoeba histolytica protein kinase domain containing protein 0.0288 0.103 0.3428
Schistosoma mansoni protein kinase 0.0054 0.0004 0.0007
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0055 0.0007 0.0009
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0195 0.0622 0.177
Entamoeba histolytica hypothetical protein 0.0056 0.0012 0.0029
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0271 0.0955 0.2721
Loa Loa (eye worm) hypothetical protein 0.0186 0.0581 0.0581
Trichomonas vaginalis CMGC family protein kinase 0.015 0.0424 0.3228
Brugia malayi Protein kinase domain containing protein 0.0095 0.018 0.018
Entamoeba histolytica PH domain containing protein kinase, putative 0.0056 0.0012 0.0029
Brugia malayi phosphoinositide-dependent protein kinase I 0.0095 0.018 0.018
Echinococcus granulosus protein kinase shaggy 0.0288 0.103 0.2494
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0288 0.103 0.103
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0234 0.0793 0.2259
Schistosoma mansoni protein kinase 0.0271 0.0955 0.1812
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0099 0.0199 0.056
Plasmodium vivax protein kinase, putative 0.0069 0.0068 0.0491
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0487 0.3714
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0263 0.0921 0.0921
Schistosoma mansoni tyrosine kinase 0.0054 0.0004 0.0007
Trichomonas vaginalis CAMK family protein kinase 0.0065 0.005 0.0355
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0234 0.0793 0.2259
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0097 0.019 0.0189
Schistosoma mansoni tyrosine kinase 0.0054 0.0004 0.0007
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0055 0.0007 0.0014
Giardia lamblia Kinase, CMGC CDK 0.0263 0.0921 0.7049
Echinococcus multilocularis 0.0349 0.13 0.3708
Brugia malayi hypothetical protein 0.0094 0.0177 0.0177
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0169 0.0509 0.3883
Loa Loa (eye worm) TK protein kinase 0.0054 0.0004 0.0003
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0054 0.0004 0.0003
Echinococcus multilocularis dual specificity 0.015 0.0424 0.1202
Echinococcus multilocularis tensin 0.0055 0.0007 0.0011
Schistosoma mansoni serine/threonine protein kinase 0.0289 0.1037 0.1967
Loa Loa (eye worm) AGC/NDR protein kinase 0.0164 0.0487 0.0487
Loa Loa (eye worm) TK/FER protein kinase 0.0054 0.0004 0.0003
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0594 0.2378 0.2377
Entamoeba histolytica casein kinase, putative 0.0112 0.0259 0.0853
Trichomonas vaginalis CMGC family protein kinase 0.0097 0.019 0.1429
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0174 0.0529 0.0529
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0214 0.1614
Brugia malayi hypothetical protein 0.0054 0.0004 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0271 0.0955 0.1811
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0214 0.1614
Echinococcus granulosus casein kinase I alpha 0.0121 0.0295 0.0709
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0249 0.0858 0.2074
Schistosoma mansoni protein kinase 0.0054 0.0004 0.0007
Giardia lamblia Kinase, CMGC MAPK 0.0097 0.019 0.1429
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0084 0.0135 0.0319
Echinococcus granulosus dual specificity 0.0134 0.0353 0.0848
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0288 0.103 0.7885
Brugia malayi Protein kinase domain containing protein 0.085 0.35 0.3499
Echinococcus granulosus casein kinase I gamma 0.0222 0.0739 0.1785
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0121 0.0295 0.2241
Loa Loa (eye worm) hypothetical protein 0.0055 0.0007 0.0007
Leishmania major protein kinase, putative 0.0271 0.0955 0.7309
Echinococcus granulosus aurora kinase A 0.0271 0.0955 0.2311
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0249 0.0858 0.2443
Echinococcus granulosus hypothetical protein 0.0055 0.0007 0.0009
Echinococcus granulosus insulin receptor 0.0442 0.1709 0.4143
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0167 0.0499 0.3802
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0113 0.0262 0.1986
Entamoeba histolytica protein kinase, putative 0.0056 0.0012 0.0029
Schistosoma mansoni shc transforming protein 0.0055 0.0007 0.0014
Trichomonas vaginalis AGC family protein kinase 0.0147 0.0412 0.3135
Echinococcus multilocularis tyrosine protein kinase Blk 0.0194 0.0619 0.1761
Brugia malayi Protein kinase c protein 2 0.0128 0.0325 0.0325
Echinococcus multilocularis c src tyrosine kinase 0.0149 0.0421 0.1192
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0209 0.0686 0.1656
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0126 0.0319 0.0318
Schistosoma mansoni tyrosine kinase 0.0599 0.2398 0.4549
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0402 0.1532 0.3713
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.024 0.0818 0.0818
Giardia lamblia Kinase, CMGC CDK 0.0263 0.0921 0.7049
Onchocerca volvulus 0.0054 0.0004 0.0009
Entamoeba histolytica protein kinase domain containing protein 0.0134 0.0353 0.1166
Echinococcus multilocularis cyclin dependent kinase 5 0.0263 0.0921 0.2625
Onchocerca volvulus 0.0442 0.1709 0.4884
Loa Loa (eye worm) TK protein kinase 0.0054 0.0004 0.0003
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0245 0.0844 0.204
Schistosoma mansoni serine/threonine protein kinase 0.0084 0.0135 0.0256
Trypanosoma cruzi cdc2-related kinase 3 0.0263 0.0921 0.7049
Loa Loa (eye worm) TK/FER protein kinase 0.011 0.0246 0.0246
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.015 0.0424 0.0424
Echinococcus granulosus Protein kinase C brain isozyme 0.0244 0.0838 0.2026
Plasmodium falciparum protein kinase 5 0.0263 0.0921 0.7049
Brugia malayi Egg laying defective protein 4 0.0146 0.0405 0.0405
Schistosoma mansoni serine/threonine kinase 0.0225 0.0754 0.1431
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0102 0.0214 0.1614
Brugia malayi Protein kinase domain containing protein 0.0054 0.0004 0.0003
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0096 0.0185 0.044
Onchocerca volvulus 0.0121 0.0295 0.0843
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0351 0.1306 1
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0434 0.1674 0.4057
Echinococcus multilocularis protein tyrosine kinase 0.0542 0.2149 0.6135
Schistosoma mansoni tyrosine kinase 0.0442 0.1709 0.3242
Entamoeba histolytica protein kinase, putative 0.0056 0.0012 0.0029
Brugia malayi Cam kinase protein 1 0.0113 0.0262 0.0262
Schistosoma mansoni protein kinase 0.0054 0.0004 0.0007
Brugia malayi Variant SH3 domain containing protein 0.0065 0.0051 0.005
Brugia malayi Immunoglobulin I-set domain containing protein 0.0266 0.0934 0.0934
Leishmania major protein kinase, putative 0.0098 0.0194 0.1459
Onchocerca volvulus Serine\/threonine kinase homolog 0.0277 0.098 0.28
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0084 0.0135 0.0319
Brugia malayi intracellular kinase 0.0288 0.103 0.103
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0351 0.1306 1
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0102 0.0214 0.0601
Echinococcus granulosus Immunoglobulin 0.0079 0.0111 0.026
Echinococcus granulosus dual specificity protein kinase clk2 0.0351 0.1306 0.3162
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.085 0.35 1
Brugia malayi Protein kinase domain containing protein 0.0594 0.2378 0.2377
Loa Loa (eye worm) casein kinase 0.0174 0.0529 0.0528
Loa Loa (eye worm) TK/ABL protein kinase 0.031 0.1125 0.1125
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0321 0.1174 0.2842
Loa Loa (eye worm) hypothetical protein 0.0115 0.0269 0.0268
Trichomonas vaginalis CAMK family protein kinase 0.0277 0.098 0.7501
Echinococcus granulosus protein kinase c epsilon type 0.0206 0.067 0.1618
Entamoeba histolytica protein kinase, putative 0.0114 0.0268 0.0881
Echinococcus granulosus serine:threonine protein kinase 3 0.0264 0.0923 0.2234
Echinococcus granulosus titin 0.0083 0.0131 0.0309
Echinococcus multilocularis nervana 2 0.0119 0.0289 0.0816
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0097 0.019 0.1429
Echinococcus multilocularis NCK adaptor protein 0.0097 0.019 0.0533
Entamoeba histolytica protein kinase, putative 0.0054 0.0004 0.000000022164
Trypanosoma cruzi casein kinase, putative 0.0121 0.0295 0.2241
Trichomonas vaginalis AGC family protein kinase 0.0249 0.0858 0.6559
Loa Loa (eye worm) hypothetical protein 0.0138 0.037 0.037
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.2329 1 1
Schistosoma mansoni nck2/grb4 0.0095 0.0182 0.0345
Trichomonas vaginalis CAMK family protein kinase 0.0277 0.098 0.7501
Plasmodium vivax serine/threonine protein kinase, putative 0.0096 0.0187 0.1409
Echinococcus granulosus SH2 domain containing protein 7 0.0055 0.0007 0.0009
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0271 0.0955 0.2722
Trypanosoma brucei rac serine-threonine kinase, putative 0.0292 0.1049 0.803
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0113 0.0262 0.074
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0054 0.0004 0.0003
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0271 0.0955 0.3178
Schistosoma mansoni tyrosine kinase 0.0054 0.0004 0.0007
Schistosoma mansoni serine/threonine protein kinase 0.0224 0.075 0.1423
Brugia malayi Protein kinase domain containing protein 0.0164 0.0487 0.0487
Echinococcus granulosus ephrin type A receptor 4 A 0.0116 0.0275 0.0659
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0134 0.0353 0.2683
Trypanosoma cruzi casein kinase, putative 0.0121 0.0295 0.2241
Entamoeba histolytica SH2 domain containing protein 0.0055 0.0007 0.0013
Schistosoma mansoni tensin 0.0055 0.0007 0.0014
Loa Loa (eye worm) hypothetical protein 0.0054 0.0004 0.0003
Trichomonas vaginalis AGC family protein kinase 0.0292 0.1049 0.803
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0277 0.098 0.2794
Trichomonas vaginalis AGC family protein kinase 0.0095 0.018 0.1356
Schistosoma mansoni serine/threonine protein kinase 0.0102 0.0214 0.0406
Trichomonas vaginalis AGC family protein kinase 0.0095 0.018 0.1356
Brugia malayi Protein kinase domain containing protein 0.0054 0.0004 0.0003
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0012 0.0068
Brugia malayi Furin-like cysteine rich region family protein 0.0599 0.2398 0.2398
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0098 0.0194 0.0635
Schistosoma mansoni vesicular amine transporter 0.0079 0.0111 0.021
Entamoeba histolytica protein kinase domain containing protein 0.015 0.0424 0.1403
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0288 0.103 0.7885
Schistosoma mansoni tyrosine kinase 0.0054 0.0004 0.0007
Brugia malayi Hr1 repeat family protein 0.0289 0.1037 0.1036
Echinococcus granulosus CDC7 cell division cycle 7 0.0278 0.0987 0.2388
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0264 0.0923 0.0923
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0087 0.0148 0.0148
Schistosoma mansoni serine/threonine protein kinase 0.0195 0.0622 0.118
Brugia malayi P38 map kinase family protein 2 0.0169 0.0509 0.0509
Loa Loa (eye worm) protein kinase domain-containing protein 0.0222 0.0739 0.0738
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0234 0.0793 0.2259
Schistosoma mansoni serine/threonine-protein kinase 0.0176 0.0537 0.1018
Echinococcus multilocularis activin receptor type 0.0102 0.0214 0.06
Brugia malayi Protein kinase domain containing protein 0.0054 0.0004 0.0003
Onchocerca volvulus 0.0055 0.0007 0.002
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0262 0.0498
Echinococcus granulosus integrin linked protein kinase 0.0054 0.0004 0.000000016121
Echinococcus granulosus tyrosine protein kinase ABL1 0.031 0.1125 0.2725
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0186 0.0581 0.1652
Plasmodium vivax unspecified product 0.0112 0.0259 0.1963
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0056 0.0012 0.0068
Echinococcus multilocularis integrin linked protein kinase 0.0054 0.0004 0.000000018985
Schistosoma mansoni kinase 0.0294 0.1058 0.2008
Echinococcus granulosus protein kinase 0.0349 0.13 0.3149
Echinococcus granulosus cGMP dependent protein kinase 0.0146 0.0405 0.0976
Schistosoma mansoni tyrosine kinase 0.0542 0.2149 0.4076
Entamoeba histolytica protein kinase, putative 0.0271 0.0955 0.3178
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0321 0.1176 0.1176
Loa Loa (eye worm) hypothetical protein 0.0187 0.0585 0.0585
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0396 0.1505 0.1505
Echinococcus granulosus SH2 motif 0.0055 0.0007 0.0009
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0246 0.0844 0.2041
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0214 0.1614
Leishmania major protein kinase, putative 0.0102 0.0214 0.1612
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0055 0.0007 0.002
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0214 0.1614
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0054 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0249 0.0858 0.0857
Echinococcus granulosus tyrosine protein kinase Src42A 0.0234 0.0793 0.1918
Brugia malayi Kinase associated domain 1 family protein 0.0098 0.0197 0.0196
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0054 0.0004 0.000000050977
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0209 0.0686 0.195
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0095 0.018 0.0505
Loa Loa (eye worm) TK protein kinase 0.0054 0.0004 0.0003
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0194 0.0619 0.1761
Toxoplasma gondii NEK kinase 0.0065 0.005 0.0355
Brugia malayi Protein kinase domain containing protein 0.0164 0.0487 0.0487
Echinococcus granulosus NDR protein kinase 0.0164 0.0487 0.1175
Brugia malayi Variant SH3 domain containing protein 0.0095 0.0182 0.0181
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0113 0.0262 0.0262
Entamoeba histolytica protein kinase, putative 0.0134 0.0353 0.1166
Brugia malayi Receptor family ligand binding region containing protein 0.0054 0.0004 0.0003
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.015 0.0424 0.3228
Schistosoma mansoni protein kinase 0.0054 0.0004 0.0007
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0097 0.019 0.1429
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0096 0.0187 0.1409
Loa Loa (eye worm) AGC/PKN protein kinase 0.0289 0.1037 0.1036
Echinococcus granulosus signal transduction protein lnk realted 0.0055 0.0007 0.0009
Schistosoma mansoni protein kinase 0.0102 0.0214 0.0405
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0102 0.0214 0.1614
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0113 0.0262 0.0628
Brugia malayi Protein kinase domain containing protein 0.0054 0.0004 0.0003
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0084 0.0135 0.0376
Echinococcus granulosus growth factor receptor bound protein 2 0.0097 0.019 0.0453
Onchocerca volvulus 0.0054 0.0004 0.0009
Trichomonas vaginalis STE family protein kinase 0.0098 0.0194 0.1459
Brugia malayi casein kinase 1, delta 0.0121 0.0295 0.0295
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0095 0.0182 0.0345
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0252 0.0872 0.2485
Echinococcus multilocularis serine:threonine protein kinase 3 0.0264 0.0923 0.2631
Echinococcus multilocularis aurora kinase A 0.0271 0.0955 0.2722
Loa Loa (eye worm) hypothetical protein 0.0054 0.0004 0.0003
Trichomonas vaginalis CAMK family protein kinase 0.0065 0.005 0.0355
Brugia malayi Immunoglobulin I-set domain containing protein 0.0083 0.0131 0.0131
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0186 0.0581 0.1402
Echinococcus granulosus tyrosine protein kinase Fyn 0.0234 0.0793 0.1918
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0012 0.0068
Trichomonas vaginalis CK1 family protein kinase 0.0121 0.0295 0.2241
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0097 0.019 0.1429
Echinococcus multilocularis Glutaredoxin protein 5 0.0119 0.0289 0.0816
Echinococcus multilocularis mitogen activated protein kinase 14 0.0169 0.0509 0.1446
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0174 0.053 0.053
Brugia malayi Pre-SET motif family protein 0.0251 0.0869 0.0869
Loa Loa (eye worm) AGC/PKG protein kinase 0.0146 0.0405 0.0405
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0249 0.0858 0.2074
Entamoeba histolytica protein kinase, putative 0.0139 0.0376 0.1245
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0234 0.0793 0.1918
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0351 0.1306 1
Trichomonas vaginalis STE family protein kinase 0.0147 0.0412 0.3135
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0055 0.0007 0.0009
Echinococcus granulosus tyrosine kinase 0.011 0.0246 0.059
Echinococcus granulosus fibroblast growth factor receptor 4 0.0246 0.0844 0.2041
Onchocerca volvulus 0.0187 0.0585 0.1671
Loa Loa (eye worm) TK/FER protein kinase 0.011 0.0246 0.0246
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0174 0.053 0.1279
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0097 0.019 0.1429
Loa Loa (eye worm) hypothetical protein 0.0201 0.0647 0.0647
Echinococcus granulosus rho-associated protein kinase 1 0.0781 0.3197 0.7757
Trichomonas vaginalis CMGC family protein kinase 0.015 0.0424 0.3228
Entamoeba histolytica ankyrin repeat protein 0.0054 0.0004 0.000000022164
Loa Loa (eye worm) protein kinase domain-containing protein 0.0054 0.0004 0.0003
Echinococcus multilocularis serine:threonine protein kinase N2 0.0125 0.0314 0.0888
Echinococcus multilocularis tyrosine protein kinase HCK 0.0139 0.0376 0.1066
Brugia malayi Protein kinase domain containing protein 0.0278 0.0987 0.0987
Trichomonas vaginalis STE family protein kinase 0.0078 0.0108 0.0798
Loa Loa (eye worm) transcription factor SMAD2 0.0136 0.0362 0.0362
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0147 0.0412 0.3135
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.053 0.1006
Echinococcus granulosus dual specificity 0.015 0.0424 0.1021
Schistosoma mansoni adapter molecule crk 0.0095 0.0182 0.0345
Onchocerca volvulus 0.0054 0.0004 0.0009
Loa Loa (eye worm) TK/FER protein kinase 0.011 0.0246 0.0246
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.019 0.036
Echinococcus multilocularis casein kinase i 0.0121 0.0295 0.0834
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0245 0.0844 0.2403
Trichomonas vaginalis STE family protein kinase 0.0099 0.0199 0.1504
Trichomonas vaginalis CMGC family protein kinase 0.0288 0.103 0.7885
Toxoplasma gondii aurora kinase 0.0271 0.0955 0.7309
Echinococcus granulosus casein kinase I delta 0.0121 0.0295 0.0709
Echinococcus granulosus serine:threonine protein kinase 0.0126 0.0319 0.0765
Schistosoma mansoni serine/threonine protein kinase 0.0068 0.0065 0.0123
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0186 0.0581 0.4435
Trichomonas vaginalis CMGC family protein kinase 0.0097 0.019 0.1429
Giardia lamblia Kinase, CAMK CAMKL 0.0102 0.0214 0.1614
Brugia malayi Protein kinase domain containing protein 0.0282 0.1006 0.1006
Plasmodium falciparum calcium-dependent protein kinase 7 0.0056 0.0012 0.0068
Trichomonas vaginalis AGC family protein kinase 0.0292 0.1049 0.803
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0056 0.0012 0.0068
Brugia malayi serine/threonine protein kinase 6 0.0271 0.0955 0.0955
Loa Loa (eye worm) hypothetical protein 0.0131 0.034 0.0339
Schistosoma mansoni serine/threonine protein kinase 0.0102 0.0214 0.0406
Loa Loa (eye worm) TK/FER protein kinase 0.011 0.0246 0.0246
Trypanosoma brucei Casein kinase II 0.0112 0.0259 0.1963
Brugia malayi Protein kinase domain containing protein 0.0202 0.0652 0.0652
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0099 0.0199 0.0476
Brugia malayi Protein kinase domain 0.0099 0.0199 0.0199
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.1303 0.5492 0.5492
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0214 0.1614
Schistosoma mansoni serine/threonine protein kinase 0.0069 0.0067 0.0126
Giardia lamblia Kinase, CAMK CAMKL 0.0102 0.0214 0.1614
Schistosoma mansoni protein kinase C mu 0.0226 0.0757 0.1436
Schistosoma mansoni serine/threonine protein kinase 0.0351 0.1306 0.2477
Schistosoma mansoni serine/threonine protein kinase 0.0262 0.0916 0.1737
Loa Loa (eye worm) hypothetical protein 0.0055 0.0007 0.0007
Echinococcus multilocularis signal transduction protein lnk realted 0.0055 0.0007 0.0011
Trypanosoma brucei Serine/threonine-protein kinase NEK11, putative 0.0065 0.005 0.0355
Brugia malayi Protein kinase domain containing protein 0.0054 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0174 0.053 0.053
Onchocerca volvulus 0.011 0.0246 0.0703
Echinococcus granulosus protein kinase c iota type 0.0285 0.1016 0.2458
Echinococcus multilocularis tyrosine kinase 0.011 0.0246 0.0694
Echinococcus multilocularis mitogen activated protein kinase 14 0.0169 0.0509 0.1446
Echinococcus granulosus dual specificity 0.015 0.0424 0.1021
Schistosoma mansoni protein kinase 0.0535 0.2116 0.4015
Plasmodium falciparum protein serine/threonine kinase-1 0.0351 0.1306 1
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0249 0.0858 0.6559
Echinococcus granulosus casein kinase I delta 0.0121 0.0295 0.0709
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0335 0.1239 0.1239
Echinococcus granulosus serine:threonine protein kinase N2 0.0289 0.1037 0.2509
Loa Loa (eye worm) RGC/RGC protein kinase 0.0054 0.0004 0.0003
Brugia malayi protein kinase C3,putative 0.0168 0.0503 0.0503
Echinococcus multilocularis casein kinase I alpha 0.0121 0.0295 0.0834
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0169 0.0509 0.3883
Plasmodium vivax glycogen synthase kinase 3, putative 0.0288 0.103 0.7885
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0079 0.0111 0.021
Trichomonas vaginalis CAMK family protein kinase 0.0138 0.0371 0.2818
Loa Loa (eye worm) hypothetical protein 0.0113 0.0262 0.0262
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0137 0.0369 0.2806
Schistosoma mansoni tyrosine kinase 0.0054 0.0004 0.0007
Brugia malayi Protein kinase domain containing protein 0.011 0.0246 0.0246
Echinococcus multilocularis serine:threonine protein kinase N2 0.0164 0.0487 0.1383
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0012 0.0068
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0398 0.1516 0.3673
Leishmania major casein kinase, putative 0.0121 0.0295 0.2241
Leishmania major protein kinase, putative 0.0056 0.0012 0.0068
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0271 0.0955 0.2311
Echinococcus multilocularis cyclin dependent kinase 1 0.0263 0.0921 0.2625
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0054 0.0004 0.0007
Echinococcus multilocularis serine:threonine protein kinase 0.0126 0.0319 0.0901
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0249 0.0858 0.0857
Schistosoma mansoni protein kinase 0.0434 0.1674 0.3175
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0055 0.0007 0.0014
Loa Loa (eye worm) hypothetical protein 0.0055 0.0007 0.0007
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0055 0.0007 0.0011
Loa Loa (eye worm) hypothetical protein 0.0134 0.0353 0.0352
Brugia malayi hypothetical protein 0.011 0.0246 0.0246
Echinococcus granulosus hypothetical protein 0.0303 0.1096 0.2653
Schistosoma mansoni serine/threonine protein kinase 0.0164 0.0487 0.0924
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0119 0.0289 0.0693
Echinococcus multilocularis serine:threonine protein kinase N2 0.0289 0.1037 0.2955
Brugia malayi bone morphogenetic protein type 1 receptor 0.0054 0.0004 0.0003
Echinococcus multilocularis 0.0055 0.0007 0.0011
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0096 0.0185 0.0518
Trypanosoma brucei protein kinase, putative 0.0097 0.019 0.1429
Echinococcus multilocularis mitogen activated protein kinase 0.0097 0.019 0.0532
Loa Loa (eye worm) hypothetical protein 0.0054 0.0004 0.0003
Loa Loa (eye worm) TK/FER protein kinase 0.0054 0.0004 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0277 0.098 0.186
Loa Loa (eye worm) hypothetical protein 0.0054 0.0004 0.0003
Giardia lamblia Kinase, NEK 0.0054 0.0004 0.000000050977
Brugia malayi Protein kinase domain containing protein 0.0442 0.1709 0.1709
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0164 0.0487 0.1175
Echinococcus multilocularis casein kinase I gamma 0.0222 0.0739 0.2102
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0054 0.0004 0.0003
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0194 0.0619 0.1495
Brugia malayi Serine/threonine-protein kinase Pim-3 0.085 0.35 0.3499
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0487 0.3714
Onchocerca volvulus 0.0083 0.0131 0.0373
Entamoeba histolytica cell division protein kinase 2, putative 0.0263 0.0921 0.3065
Loa Loa (eye worm) hypothetical protein 0.0594 0.2378 0.2377
Loa Loa (eye worm) hypothetical protein 0.0054 0.0004 0.0003
Trypanosoma cruzi polo-like protein kinase, putative 0.0277 0.098 0.7501
Giardia lamblia Kinase, CMGC GSK 0.0288 0.103 0.7885
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0351 0.1306 1
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0448 0.1732 0.4944
Echinococcus granulosus tyrosine protein kinase Srms 0.0503 0.1974 0.4786
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0055 0.0007 0.0011
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0056 0.0012 0.0068
Echinococcus granulosus epidermal growth factor receptor 0.0398 0.1516 0.3673
Loa Loa (eye worm) hypothetical protein 0.0054 0.0004 0.0003
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0164 0.0487 0.0487
Schistosoma mansoni serine/threonine protein kinase 0.0736 0.2998 0.5688
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0054 0.0004 0.0003
Giardia lamblia Aurora kinase 0.0271 0.0955 0.7309
Brugia malayi serine/threonine-protein kinase 6 0.0271 0.0955 0.0955
Echinococcus granulosus titin 0.0083 0.0131 0.0309
Brugia malayi Protein kinase domain containing protein 0.0134 0.0353 0.0353
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0012 0.0068
Brugia malayi Protein kinase domain containing protein 0.0126 0.0319 0.0318
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0288 0.103 0.103
Brugia malayi Fibronectin type III domain containing protein 0.0094 0.0177 0.0177
Loa Loa (eye worm) TK/FER protein kinase 0.011 0.0246 0.0246
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0056 0.0012 0.0068
Schistosoma mansoni serine/threonine protein kinase 0.0263 0.0921 0.1748
Plasmodium falciparum NIMA related kinase 2 0.0065 0.005 0.0355
Brugia malayi Protein kinase domain containing protein 0.0054 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0303 0.1096 0.1095
Entamoeba histolytica protein kinase, putative 0.015 0.0424 0.1403
Trichomonas vaginalis TKL family protein kinase 0.0054 0.0004 0.000000050977
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0448 0.1732 0.4198
Echinococcus granulosus twitchin 0.0147 0.041 0.0988
Echinococcus multilocularis protein kinase c iota type 0.0285 0.1016 0.2895
Schistosoma mansoni protein kinase 0.0202 0.0652 0.1237
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0095 0.018 0.018
Trypanosoma cruzi polo-like protein kinase, putative 0.0277 0.098 0.7501
Entamoeba histolytica PH domain containing protein kinase, putative 0.0257 0.0896 0.2978
Onchocerca volvulus 0.0055 0.0007 0.002
Toxoplasma gondii casein kinase I 0.0121 0.0295 0.2241
Brugia malayi Protein kinase domain containing protein 0.0076 0.0097 0.0097
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0288 0.103 0.2494
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0147 0.0412 0.3135
Trypanosoma brucei casein kinase I, isoform 2 0.0121 0.0295 0.2241
Brugia malayi C-terminal src kinase protein 1 0.0054 0.0004 0.0003
Entamoeba histolytica p21-activated kinase 0.0108 0.0237 0.078
Schistosoma mansoni tyrosine kinase 0.0398 0.1516 0.2876
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0249 0.0858 0.2443
Schistosoma mansoni serine/threonine protein kinase 0.0146 0.0405 0.0769
Giardia lamblia Kinase, NEK 0.0147 0.0412 0.3135
Schistosoma mansoni serine/threonine protein kinase 0.0351 0.1306 0.2477
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0069 0.0067 0.0066
Leishmania major protein kinase, putative 0.0065 0.005 0.0355
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0186 0.0581 0.4435
Brugia malayi Temporarily assigned gene name protein 59 0.0186 0.0581 0.0581
Schistosoma mansoni growth factor receptor-bound protein 0.0095 0.0182 0.0345
Echinococcus multilocularis Immunoglobulin 0.0079 0.0111 0.0306
Brugia malayi Tyrosine-protein kinase PR2 0.0054 0.0004 0.0003
Plasmodium falciparum serine/threonine protein kinase, putative 0.0271 0.0955 0.7309
Echinococcus multilocularis growth factor receptor bound protein 2 0.0095 0.0182 0.0509
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0075 0.0094 0.0219
Entamoeba histolytica tyrosin kinase, putative 0.0057 0.0017 0.0045
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0156 0.0449 0.1273
Echinococcus granulosus casein kinase I alpha 0.0121 0.0295 0.0709
Schistosoma mansoni tyrosine kinase 0.0085 0.0137 0.0259
Echinococcus granulosus epidermal growth factor receptor 0.0599 0.2398 0.5816
Giardia lamblia Kinase, STE STE20 0.0098 0.0194 0.1459
Echinococcus granulosus tyrosine protein kinase 0.0286 0.102 0.2468
Schistosoma mansoni protein kinase 0.0252 0.0872 0.1655
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0069 0.0067 0.0483
Onchocerca volvulus 0.0186 0.0581 0.1659
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0056 0.0012 0.0068
Brugia malayi ephrin receptor 1 precursor 0.0083 0.0132 0.0131
Echinococcus granulosus tyrosine protein kinase Fyn 0.0234 0.0793 0.1918
Loa Loa (eye worm) TK/FER protein kinase 0.011 0.0246 0.0246
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0055 0.0007 0.0007
Trichomonas vaginalis CAMK family protein kinase 0.0277 0.098 0.7501
Loa Loa (eye worm) hypothetical protein 0.0054 0.0004 0.0003
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0214 0.1614
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0271 0.0955 0.7309
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0351 0.1306 1
Onchocerca volvulus 0.0089 0.0157 0.0449
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0113 0.0262 0.0262
Toxoplasma gondii NEK kinase 0.0065 0.005 0.0355
Echinococcus multilocularis PAK box P21 Rho binding 0.0078 0.0108 0.0297
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.0029 0.0029
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0012 0.0068
Brugia malayi serine/threonine-protein kinase plk-2 0.0277 0.098 0.098
Trypanosoma cruzi cdc2-related kinase 1 0.0263 0.0921 0.7049
Schistosoma mansoni titin 0.0083 0.0131 0.0248
Trichomonas vaginalis CMGC family protein kinase 0.0278 0.0987 0.7552
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0056 0.0012 0.0068
Entamoeba histolytica hypothetical protein 0.0366 0.1375 0.4581
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0134 0.0353 0.2683
Schistosoma mansoni serine/threonine protein kinase 0.0476 0.1856 0.3521
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0055 0.0005 0.0004
Entamoeba histolytica protein kinase, putative 0.0087 0.0145 0.0473
Brugia malayi SH2 domain containing protein 0.0055 0.0007 0.0007
Loa Loa (eye worm) AGC/PKA protein kinase 0.0249 0.0858 0.0857
Entamoeba histolytica protein kinase, putative 0.0078 0.0108 0.0347
Echinococcus granulosus mitogen activated protein kinase 14 0.0169 0.0509 0.1228
Trichomonas vaginalis TKL family protein kinase 0.0054 0.0004 0.000000050977
Echinococcus granulosus N chimaerin 0.0096 0.0185 0.044
Loa Loa (eye worm) hypothetical protein 0.0055 0.0007 0.0007
Leishmania major serine/threonine-protein kinase, putative 0.0065 0.005 0.0355
Schistosoma mansoni tyrosine kinase 0.0092 0.0169 0.032
Plasmodium vivax serine/threonine-protein kinase NEK4, putative 0.0065 0.005 0.0355
Entamoeba histolytica cell division protein kinase 2, putative 0.0263 0.0921 0.3065
Trichomonas vaginalis set domain proteins, putative 0.0286 0.1022 0.7822
Loa Loa (eye worm) hypothetical protein 0.0055 0.0007 0.0007
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0262 0.1986
Schistosoma mansoni hypothetical protein 0.0055 0.0007 0.0014
Trichomonas vaginalis CMGC family protein kinase 0.0278 0.0987 0.7552
Trichomonas vaginalis CAMK family protein kinase 0.0225 0.0754 0.5766
Trichomonas vaginalis CK1 family protein kinase 0.0121 0.0295 0.2241
Brugia malayi Protein kinase domain containing protein 0.0286 0.102 0.1019
Loa Loa (eye worm) hypothetical protein 0.0064 0.0045 0.0045
Entamoeba histolytica serine/threonine protein kinase, putative 0.0102 0.0214 0.0702
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0214 0.1614
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0097 0.019 0.1429
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0099 0.0199 0.056
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0226 0.0757 0.0757
Schistosoma mansoni hypothetical protein 0.0098 0.0197 0.0373
Echinococcus multilocularis epidermal growth factor receptor 0.0398 0.1516 0.4326
Loa Loa (eye worm) TK/FER protein kinase 0.0054 0.0004 0.0003
Brugia malayi SH2 domain containing protein 0.0402 0.1532 0.1532
Loa Loa (eye worm) TK protein kinase 0.0139 0.0376 0.0376
Brugia malayi MAP kinase sur-1 0.0097 0.019 0.0189
Echinococcus granulosus activin receptor type 0.0102 0.0214 0.051
Entamoeba histolytica hypothetical protein 0.0055 0.0005 0.0004
Entamoeba histolytica protein kinase 2, putative 0.0167 0.0499 0.1653
Schistosoma mansoni protein kinase 0.0054 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.006 0.0029 0.0029
Trichomonas vaginalis AGC family protein kinase 0.0173 0.0525 0.4005
Schistosoma mansoni serine/threonine protein kinase 0.023 0.0777 0.1473
Loa Loa (eye worm) TK/DDR protein kinase 0.0054 0.0004 0.0003
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0056 0.0012 0.0068
Onchocerca volvulus 0.0054 0.0004 0.0009
Schistosoma mansoni serine/threonine protein kinase 0.0206 0.067 0.1271
Trichomonas vaginalis AGC family protein kinase 0.0292 0.1049 0.803
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0206 0.067 0.0669
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0096 0.0187 0.1409
Entamoeba histolytica protein kinase, putative 0.0134 0.0353 0.1166
Leishmania major protein kinase, putative,serine/threonine-protein kinase Nek1, putative 0.0065 0.005 0.0355
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.018 0.0342
Schistosoma mansoni tyrosine kinase 0.0054 0.0004 0.0007
Loa Loa (eye worm) TK/Met protein kinase 0.0054 0.0004 0.0003
Brugia malayi Protein kinase domain containing protein 0.0448 0.1732 0.1732
Schistosoma mansoni tyrosine kinase 0.0398 0.1516 0.2876
Echinococcus granulosus tensin 0.0055 0.0007 0.0009
Onchocerca volvulus 0.0278 0.0987 0.2819
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0249 0.0858 0.6559
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0054 0.0004 0.0003
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0065 0.005 0.0355
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0054 0.0004 0.0007
Trypanosoma brucei protein kinase, putative 0.0102 0.0214 0.1612
Schistosoma mansoni tyrosine kinase 0.0344 0.1277 0.2423
Trichomonas vaginalis CMGC family protein kinase 0.0112 0.0259 0.1963
Brugia malayi Protein kinase domain containing protein 0.0054 0.0004 0.0003
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0012 0.0068
Entamoeba histolytica protein kinase, putative 0.0084 0.0135 0.0439
Loa Loa (eye worm) hypothetical protein 0.0086 0.0143 0.0143
Loa Loa (eye worm) serine/threonine protein kinase 0.0054 0.0004 0.0003
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0288 0.103 0.2936
Echinococcus multilocularis calcium dependent protein kinase 0.0065 0.0052 0.0139
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0056 0.0012 0.0068
Echinococcus granulosus serine:threonine protein kinase TAO1 0.023 0.0777 0.1877
Loa Loa (eye worm) CAMK protein kinase 0.0083 0.0131 0.0131
Brugia malayi Protein kinase domain containing protein 0.011 0.0246 0.0246
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0402 0.1532 0.4372
Loa Loa (eye worm) CAMK/PIM protein kinase 0.085 0.35 0.3499
Trichomonas vaginalis AGC family protein kinase 0.0056 0.0012 0.0068
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0113 0.0262 0.1986
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0224 0.075 0.2136
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0234 0.0793 0.2259
Echinococcus multilocularis neuroglian 0.0099 0.0201 0.0563
Echinococcus multilocularis casein kinase I delta 0.0121 0.0295 0.0834
Entamoeba histolytica hypothetical protein 0.0056 0.0012 0.0029
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0224 0.075 0.1814
Echinococcus multilocularis cyclin dependent kinase 1 0.0263 0.0921 0.2625
Echinococcus multilocularis tyrosine protein kinase Abl 0.0226 0.0757 0.2154
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0056 0.0012 0.0068
Loa Loa (eye worm) hypothetical protein 0.0055 0.0007 0.0007
Schistosoma mansoni tyrosine kinase 0.0054 0.0004 0.0007
Brugia malayi hypothetical protein 0.023 0.0777 0.0776
Loa Loa (eye worm) hypothetical protein 0.0138 0.037 0.037
Entamoeba histolytica casein kinase, putative 0.0121 0.0295 0.0974
Entamoeba histolytica protein kinase, putative 0.0113 0.0262 0.0864
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.0181 0.0343
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0102 0.0214 0.1612
Loa Loa (eye worm) hypothetical protein 0.0215 0.0712 0.0711
Trypanosoma brucei polo-like protein kinase 0.0277 0.098 0.7501
Loa Loa (eye worm) hypothetical protein 0.0096 0.0186 0.0185
Leishmania major casein kinase II, putative 0.0112 0.0259 0.1963
Schistosoma mansoni tyrosine kinase 0.0149 0.0421 0.0798
Loa Loa (eye worm) hypothetical protein 0.0054 0.0004 0.0004
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0099 0.0199 0.056
Brugia malayi map kinase activated protein kinase protein 2 0.0396 0.1505 0.1505
Echinococcus multilocularis serine:threonine protein kinase 38 0.0164 0.0487 0.1383
Trichomonas vaginalis AGC family protein kinase 0.0271 0.0955 0.7309
Entamoeba histolytica protein kinase, putative 0.0084 0.0135 0.0439
Giardia lamblia Kinase, AGC PKA 0.0249 0.0858 0.6559
Loa Loa (eye worm) hypothetical protein 0.0094 0.0177 0.0177
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0164 0.0487 0.1383
Brugia malayi Protein kinase domain containing protein 0.0351 0.1306 0.1305
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0224 0.075 0.1814
Echinococcus granulosus protein tyrosine kinase 0.0542 0.2149 0.521
Loa Loa (eye worm) hypothetical protein 0.0298 0.1075 0.1075
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0249 0.0858 0.6559
Loa Loa (eye worm) hypothetical protein 0.0231 0.0781 0.078
Giardia lamblia Kinase, CMGC CLK 0.0351 0.1306 1
Brugia malayi protein kinase C II. 0.0206 0.067 0.0669
Schistosoma mansoni protein kinase 0.0434 0.1674 0.3175
Echinococcus multilocularis protein kinase c epsilon type 0.0206 0.067 0.1905
Trichomonas vaginalis CMGC family protein kinase 0.0278 0.0987 0.7552
Giardia lamblia Kinase, CDC7 0.0278 0.0987 0.7552
Schistosoma mansoni tyrosine kinase 0.0054 0.0004 0.0007
Entamoeba histolytica protein kinase, putative 0.0095 0.018 0.059
Schistosoma mansoni serine/threonine protein kinase 0.0278 0.0987 0.1872
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0156 0.0449 0.1081
Entamoeba histolytica serine/threonine protein kinase, putative 0.0065 0.005 0.0154
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0069 0.0067 0.0066
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0167 0.0499 0.1202
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0102 0.0214 0.0213
Onchocerca volvulus 0.0733 0.2987 0.8536
Plasmodium vivax calcium-dependent protein kinase, putative 0.0113 0.0262 0.1986
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0176 0.0537 0.4093
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0069 0.0067 0.0066
Echinococcus granulosus c-Jun N-terminal kinases 0.0271 0.0955 0.231
Schistosoma mansoni serine/threonine protein kinase 0.0222 0.0739 0.1401
Schistosoma mansoni serine/threonine protein kinase 0.0069 0.0067 0.0126
Loa Loa (eye worm) TK/CSK protein kinase 0.0054 0.0004 0.0003
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0096 0.0185 0.035
Echinococcus multilocularis titin 0.0083 0.0131 0.0364
Trypanosoma brucei protein kinase, putative 0.0288 0.103 0.7885
Brugia malayi Protein kinase domain containing protein 0.0054 0.0004 0.0003
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0214 0.1614
Echinococcus granulosus raf serine:threonine protein kinase 0.0095 0.0181 0.0431
Giardia lamblia Kinase, STE STE20 0.0099 0.0199 0.1504
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0103 0.0217 0.0714
Echinococcus granulosus suppressor of cytokine signaling 6 0.0055 0.0007 0.0009
Loa Loa (eye worm) hypothetical protein 0.0487 0.1907 0.1906
Loa Loa (eye worm) hypothetical protein 0.0102 0.0214 0.0213
Loa Loa (eye worm) hypothetical protein 0.0126 0.0319 0.0318
Loa Loa (eye worm) hypothetical protein 0.0134 0.0353 0.0352
Schistosoma mansoni protein kinase 0.0112 0.0259 0.0492
Echinococcus multilocularis roundabout 2 0.0131 0.0342 0.0968
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0174 0.053 0.1506
Loa Loa (eye worm) hypothetical protein 0.0095 0.0182 0.0181
Loa Loa (eye worm) hypothetical protein 0.0178 0.0547 0.0547
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0055 0.0007 0.0007
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0054 0.0004 0.0009
Trichomonas vaginalis AGC family protein kinase 0.0271 0.0955 0.7309
Echinococcus multilocularis myosin iiia 0.0098 0.0194 0.0544
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0113 0.0262 0.074
Schistosoma mansoni protein kinase 0.0434 0.1674 0.3175
Loa Loa (eye worm) TK/EGFR protein kinase 0.0599 0.2398 0.2398
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0102 0.0214 0.1612
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0396 0.1505 0.4296
Leishmania major folate/biopterin transporter, putative 0.0056 0.0012 0.0068
Schistosoma mansoni vam6/vps39 related 0.0186 0.0581 0.1102
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.0214 0.1614
Echinococcus granulosus serine:threonine protein kinase 0.0126 0.0319 0.0765
Brugia malayi Protein kinase domain containing protein 0.0222 0.0739 0.0738
Trypanosoma brucei SNF1-related protein kinases, putative 0.0102 0.0214 0.1614
Brugia malayi Protein kinase domain containing protein 0.0054 0.0004 0.0003
Trichomonas vaginalis CAMK family protein kinase 0.0277 0.098 0.7501
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0321 0.1176 0.1176
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.085 0.35 1
Onchocerca volvulus 0.011 0.0246 0.0703
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0186 0.0581 0.4435
Entamoeba histolytica protein kinase domain containing protein 0.0736 0.2998 1
Loa Loa (eye worm) hypothetical protein 0.0094 0.0177 0.0177
Trichomonas vaginalis TKL family protein kinase 0.0054 0.0004 0.000000050977
Leishmania major protein kinase A catalytic subunit isoform 1 0.0249 0.0858 0.6559
Entamoeba histolytica protein kinase, putative 0.0099 0.0199 0.0654
Loa Loa (eye worm) AUR protein kinase 0.0271 0.0955 0.0955
Echinococcus multilocularis 0.0303 0.1096 0.3124
Schistosoma mansoni protein tyrosine kinase 0.0054 0.0004 0.0007
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0075 0.0094 0.0257
Leishmania major protein kinase A catalytic subunit isoform 2 0.0249 0.0858 0.6559
Brugia malayi SH2 domain containing protein 0.0055 0.0007 0.0007
Schistosoma mansoni suppressor of cytokine signaling 0.0055 0.0007 0.0014
Loa Loa (eye worm) hypothetical protein 0.0186 0.0581 0.0581
Loa Loa (eye worm) hypothetical protein 0.0054 0.0004 0.0003
Schistosoma mansoni tyrosine kinase 0.0054 0.0004 0.0007
Loa Loa (eye worm) TK/FER protein kinase 0.0054 0.0004 0.0003
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0167 0.0499 0.3802
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0271 0.0955 0.0954
Echinococcus granulosus tyrosine protein kinase Blk 0.0194 0.0619 0.1495
Schistosoma mansoni vav2 0.0104 0.0223 0.0422
Entamoeba histolytica PH domain containing protein kinase, putative 0.0176 0.0537 0.178
Trypanosoma brucei cdc2-related kinase 1 0.0263 0.0921 0.7049
Giardia lamblia Kinase, NEK 0.0147 0.0412 0.3135
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0594 0.2378 0.2377
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.015 0.0424 0.3228
Plasmodium falciparum protein kinase, putative 0.0102 0.0214 0.1612
Plasmodium falciparum glycogen synthase kinase 3 0.0288 0.103 0.7885

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.1122 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) 10 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.2202 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) 14.1254 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (binding) = 22.3872 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference
Potency (functional) 44.6684 uM PubChem BioAssay. A Novel Cell-Based Assay to Identify Small Molecules for B -Galactocerebrosidase. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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