Detailed information for compound 138464

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 645.743 | Formula: C29H61NO10P2
  • H donors: 1 H acceptors: 5 LogP: 5.15 Rotable bonds: 31
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCCCCCCCCCP(=O)(OC(COP(=O)(OCC[N+](C)(C)C)[O-])COCCCCCCCCCC(=O)OC)O
  • InChi: 1S/C29H61NO10P2/c1-6-7-8-9-10-14-17-20-25-41(32,33)40-28(27-39-42(34,35)38-24-22-30(2,3)4)26-37-23-19-16-13-11-12-15-18-21-29(31)36-5/h28H,6-27H2,1-5H3,(H-,32,33,34,35)
  • InChiKey: GUBMPMUEZUKTNI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis ecdysone induced protein 78C 0.0042 0.0067 0.0067
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.1306 0.3856 0.6552
Brugia malayi PHD-finger family protein 0.0038 0.0056 0.0145
Loa Loa (eye worm) hypothetical protein 0.0181 0.0484 0.0823
Plasmodium vivax protein kinase, putative 0.0027 0.0023 0.0375
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0042 0.0067 0.0067
Brugia malayi Bromodomain associated family protein 0.0029 0.0027 0.0071
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0027 0.0133
Echinococcus multilocularis GPCR, family 2 0.0231 0.0634 0.0634
Brugia malayi jmjC domain containing protein 0.0196 0.0529 0.1372
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0061 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0042 0.0067 0.0113
Loa Loa (eye worm) jmjC domain-containing protein 0.0196 0.0529 0.0899
Entamoeba histolytica hypothetical protein 0.0305 0.0854 1
Brugia malayi hypothetical protein 0.0022 0.0007 0.0019
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0067 0.0173
Onchocerca volvulus 0.0029 0.0027 0.0095
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0059 0.0117 0.0568
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0139 0.0357 0.0607
Onchocerca volvulus 0.0086 0.0199 0.0693
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0042 0.0067 0.0113
Entamoeba histolytica Ran family GTPase 0.0115 0.0286 0.335
Echinococcus multilocularis histone acetyltransferase MYST2 0.0157 0.041 0.041
Brugia malayi beta-lactamase family protein 0.0223 0.0611 0.1584
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0035 0.0045 0.0076
Mycobacterium ulcerans lipase LipD 0.0223 0.0611 0.8257
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0053 0.0099 0.0346
Onchocerca volvulus Huntingtin homolog 0.014 0.036 0.1255
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0035 0.0045 0.0116
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0042 0.0067 0.0113
Brugia malayi PHD-finger family protein 0.0029 0.0027 0.0071
Brugia malayi PHD-finger family protein 0.0029 0.0027 0.0071
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0806 0.2359 0.4008
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0115 0.0286 0.1389
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0231 0.0634 0.1644
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0115 0.0286 0.0742
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0115 0.0286 0.4686
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0042 0.0067 0.0067
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0035 0.0045 0.0116
Brugia malayi Putative carbonic anhydrase 5 precursor 0.1306 0.3856 1
Plasmodium falciparum SNF2 helicase, putative 0.0029 0.0027 0.0133
Mycobacterium tuberculosis Long conserved protein 0.007 0.015 0.0355
Onchocerca volvulus 0.0028 0.0023 0.0081
Schistosoma mansoni hypothetical protein 0.0083 0.0189 0.0321
Echinococcus multilocularis histone acetyltransferase myst3 0.0056 0.0109 0.0109
Echinococcus multilocularis mitogen activated protein kinase 0.0059 0.0117 0.0117
Mycobacterium tuberculosis Conserved hypothetical protein 0.007 0.015 0.0355
Loa Loa (eye worm) hypothetical protein 0.0022 0.0007 0.0012
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0045 0.0045
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0098 0.0234 0.0234
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.0514 0.1793
Onchocerca volvulus 0.0141 0.0364 0.1267
Onchocerca volvulus 0.0102 0.0247 0.086
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0042 0.0067 0.0173
Echinococcus multilocularis PHD finger protein 14 0.0029 0.0027 0.0027
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0007 0.0019
Loa Loa (eye worm) hypothetical protein 0.0022 0.0007 0.0012
Echinococcus multilocularis zinc finger protein 0.0046 0.0078 0.0078
Echinococcus granulosus translational activator gcn1 0.0035 0.0046 0.0078
Schistosoma mansoni hypothetical protein 0.0027 0.0023 0.0039
Mycobacterium tuberculosis Probable hydrolase 0.0223 0.0611 0.1447
Schistosoma mansoni hypothetical protein 0.0029 0.0027 0.0046
Loa Loa (eye worm) hypothetical protein 0.0042 0.0067 0.0113
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0145 0.0377 0.064
Loa Loa (eye worm) hypothetical protein 0.0065 0.0137 0.0233
Echinococcus multilocularis polyhomeotic proximal chromatin protein 0.0027 0.0023 0.0023
Brugia malayi Calcitonin receptor-like protein seb-1 0.0731 0.2131 0.5527
Brugia malayi nuclear receptor RXR 0.0022 0.0007 0.0019
Loa Loa (eye worm) hypothetical protein 0.0022 0.0007 0.0012
Mycobacterium leprae Probable lipase LipE 0.0223 0.0611 1
Trypanosoma brucei Ring finger domain/PHD-finger, putative 0.0029 0.0027 0.0071
Trichomonas vaginalis importin beta-1, putative 0.0151 0.0392 0.1368
Brugia malayi coiled-coil like protein 1 0.0027 0.0023 0.0059
Schistosoma mansoni hypothetical protein 0.0231 0.0634 0.1077
Echinococcus granulosus histone acetyltransferase myst3 0.0056 0.0109 0.0186
Echinococcus multilocularis high affinity choline transporter 1 0.0781 0.2281 0.2281
Loa Loa (eye worm) hypothetical protein 0.0065 0.0137 0.0233
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0127 0.0323 0.0764
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0005 0.0013
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0085 0.0195 0.0195
Onchocerca volvulus 0.0028 0.0023 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0062 0.0215
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0061 0.0123 0.021
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0035 0.0045 0.0076
Onchocerca volvulus 0.002 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0157 0.041 0.0697
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0022 0.0007 0.0012
Echinococcus multilocularis Sterile alpha motif type 0.0027 0.0023 0.0023
Entamoeba histolytica hypothetical protein 0.0151 0.0392 0.4592
Loa Loa (eye worm) AIDA-1b 0.0027 0.0023 0.0039
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0042 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0707 0.2061 0.3502
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0098 0.0234 0.0607
Schistosoma mansoni myst-related protein 0.004 0.006 0.0102
Schistosoma mansoni tar DNA-binding protein 0.0195 0.0526 0.0894
Mycobacterium ulcerans putative transglutaminase-like protein 0.007 0.015 0.0451
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0046
Schistosoma mansoni hepatitis B virus X associated protein hbxa 0.0029 0.0027 0.0046
Brugia malayi steroid hormone receptor 0.0042 0.0067 0.0173
Schistosoma mansoni hypothetical protein 0.0231 0.0634 0.1077
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0027 0.0133
Loa Loa (eye worm) hypothetical protein 0.0543 0.1568 0.2664
Loa Loa (eye worm) hypothetical protein 0.0035 0.0045 0.0076
Loa Loa (eye worm) hypothetical protein 0.0022 0.0007 0.0012
Loa Loa (eye worm) steroid hormone receptor 0.0042 0.0067 0.0113
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0027 0.0095
Mycobacterium ulcerans hypothetical protein 0.0223 0.0611 0.8257
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0123 0.032
Brugia malayi N-terminal motif family protein 0.0181 0.0484 0.1256
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0034 0.012
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0035 0.0045 0.0076
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0001 0.0001
Onchocerca volvulus 0.0976 0.2868 1
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0027 0.0447
Schistosoma mansoni jumonji/arid domain-containing protein 0.0149 0.0386 0.0656
Brugia malayi hypothetical protein 0.0185 0.0494 0.1282
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0035 0.0045 0.0076
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0042 0.0067 0.0067
Echinococcus multilocularis Transglutaminase 0.007 0.015 0.015
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0231 0.0634 0.1077
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0027 0.0133
Echinococcus multilocularis liprin alpha 2 0.0027 0.0023 0.0023
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0707 0.2061 0.5345
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0068 0.0145 0.0145
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0046
Brugia malayi PHD-finger family protein 0.0029 0.0029 0.0074
Echinococcus multilocularis mitogen activated protein kinase 3 0.0059 0.0117 0.0117
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0035 0.0045 0.0076
Schistosoma mansoni intermediate filament proteins 0.0141 0.0364 0.0618
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.0035 0.0046 0.012
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0022 0.0007 0.0007
Onchocerca volvulus 0.0029 0.0027 0.0095
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0042 0.0067 0.0113
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0025 0.0015 0.004
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0025 0.0015 0.004
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0098 0.0234 0.0555
Trichomonas vaginalis myo inositol monophosphatase, putative 0.008 0.018 0.0628
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0022 0.0007 0.0012
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0157 0.041 0.0697
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0123 0.032
Schistosoma mansoni gabp alpha 0.0085 0.0197 0.0335
Schistosoma mansoni RAR-like nuclear receptor 0.0042 0.0067 0.0113
Giardia lamblia Transglutaminase/protease, putative 0.007 0.015 0.5241
Mycobacterium ulcerans hypothetical protein 0.007 0.015 0.0451
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0115 0.0286 0.0286
Leishmania major hypothetical protein, conserved 0.0185 0.0494 0.1282
Schistosoma mansoni DNA polymerase eta 0.0061 0.0123 0.021
Loa Loa (eye worm) hypothetical protein 0.0223 0.0611 0.1038
Loa Loa (eye worm) hypothetical protein 0.0027 0.0023 0.0039
Echinococcus granulosus Transglutaminase 0.007 0.015 0.0255
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0043 0.0151
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0124 0.0311 0.0529
Schistosoma mansoni chromobox protein 0.0214 0.0583 0.099
Echinococcus multilocularis beta LACTamase domain containing family member 0.0223 0.0611 0.0611
Plasmodium vivax ataxin-2 like protein, putative 0.0185 0.0494 0.8096
Brugia malayi Ets-domain containing protein 0.0085 0.0197 0.0511
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0258 0.0714 0.1851
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0731 0.2131 0.3621
Brugia malayi Pre-SET motif family protein 0.0858 0.2514 0.652
Trypanosoma brucei DNA polymerase eta, putative 0.0061 0.0123 0.032
Schistosoma mansoni jumonji/arid domain-containing protein 0.0149 0.0386 0.0656
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0041 0.0065 0.011
Schistosoma mansoni bromodomain containing protein 0.0031 0.0034 0.0058
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0035 0.0045 0.0076
Echinococcus granulosus carbonic anhydrase 0.0707 0.2061 0.3502
Brugia malayi Bromodomain containing protein 0.0037 0.0052 0.0134
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.0514 0.1793
Trichomonas vaginalis glucosylceramidase, putative 0.0292 0.0815 0.2841
Echinococcus granulosus polycomb protein SCMH1 0.0335 0.0944 0.1605
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0042 0.0067 0.0173
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0806 0.2359 0.4008
Mycobacterium ulcerans aldehyde dehydrogenase 0.0258 0.0714 1
Brugia malayi Hypothetical C28H8.9 in chromosome III 0.0029 0.0027 0.0071
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0141 0.0364 0.0618
Echinococcus granulosus importin subunit beta 1 0.0186 0.0498 0.0846
Echinococcus multilocularis musashi 0.0141 0.0364 0.0364
Echinococcus granulosus uro adherence factor A 0.0029 0.0027 0.0046
Schistosoma mansoni hypothetical protein 0.002 0.0001 0.0001
Echinococcus multilocularis survival motor neuron protein 1 0.05 0.1441 0.1441
Brugia malayi Intermediate filament tail domain containing protein 0.0141 0.0364 0.0943
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0123 0.032
Echinococcus multilocularis GA binding protein alpha chain 0.0085 0.0197 0.0197
Echinococcus granulosus solute carrier family 5 0.0086 0.0199 0.0338
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0035 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0731 0.2131 0.3621
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0126 0.032 0.0543
Brugia malayi ImpB/MucB/SamB family protein 0.0061 0.0123 0.032
Schistosoma mansoni zinc finger protein 0.0046 0.0078 0.0133
Trypanosoma brucei PAB1-binding protein , putative 0.0185 0.0494 0.1282
Onchocerca volvulus 0.0028 0.0023 0.0081
Loa Loa (eye worm) hypothetical protein 0.0037 0.0052 0.0088
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0042 0.0067 0.0067
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0098 0.0234 0.1876
Schistosoma mansoni sodium/solute symporter 0.0086 0.0199 0.0338
Echinococcus granulosus sodium:myo inositol cotransporter 0.0086 0.0199 0.0338
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0127 0.0323 0.3745
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0035 0.0045 0.0076
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0042 0.0067 0.0173
Plasmodium falciparum histone-lysine N-methyltransferase, H3 lysine-4 specific 0.0029 0.0027 0.0133
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0027 0.0095
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0086 0.0199 0.0199
Toxoplasma gondii histone lysine methyltransferase SET1 0.0344 0.0973 0.4722
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0042 0.0067 0.0113
Schistosoma mansoni lip-related protein (liprin) alpha 0.0027 0.0023 0.0039
Brugia malayi cytoplasmic intermediate filament protein 0.0076 0.0167 0.0434
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 24 0.0027 0.0023 0.0059
Brugia malayi G-protein alpha subunit 0.0035 0.0045 0.0116
Loa Loa (eye worm) hypothetical protein 0.0073 0.016 0.0272
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0035 0.0045 0.0076
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0115 0.0286 0.0742
Trichomonas vaginalis inositol monophosphatase, putative 0.008 0.018 0.0628
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0258 0.0714 0.0714
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0062 0.0215
Plasmodium vivax SNF2 family N-terminal domain containing protein 0.0029 0.0027 0.0447
Plasmodium vivax transportin, putative 0.0035 0.0046 0.0755
Echinococcus multilocularis Zinc finger, DBF type 0.0029 0.0027 0.0027
Loa Loa (eye worm) mbt repeat family protein 0.0346 0.098 0.1664
Echinococcus granulosus chromobox protein 2 0.0214 0.0583 0.099
Trypanosoma cruzi Kinesin-13 5, putative 0.0027 0.0023 0.0059
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0035 0.0045 0.0156
Brugia malayi AIDA-1b 0.0027 0.0023 0.0059
Echinococcus multilocularis calcium release activated calcium channel 0.0927 0.2721 0.2721
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0029 0.0468
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0027 0.0095
Trichomonas vaginalis esterase, putative 0.0223 0.0611 0.2129
Trypanosoma brucei unspecified product 0.0042 0.0067 0.0173
Echinococcus multilocularis lamin dm0 0.0141 0.0364 0.0364
Echinococcus granulosus beta LACTamase domain containing family member 0.0223 0.0611 0.1038
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0053 0.0099 0.0346
Trichomonas vaginalis peptide N-glycanase, putative 0.007 0.015 0.0523
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0042 0.0067 0.0232
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0035 0.0045 0.0156
Trypanosoma cruzi hypothetical protein, conserved 0.0223 0.0611 0.1584
Mycobacterium tuberculosis Probable lipase LipD 0.0223 0.0611 0.1447
Echinococcus granulosus transportin 1 0.0035 0.0046 0.0078
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0035 0.0045 0.0116
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0123 0.032
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.008 0.018 0.0467
Schistosoma mansoni Protein orai-1 0.0927 0.2721 0.4624
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0023 0.008
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0045 0.0075 0.0362
Brugia malayi beta-lactamase family protein 0.0223 0.0611 0.1584
Echinococcus granulosus GTP binding nuclear protein Ran 0.0115 0.0286 0.0486
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0083 0.0189 0.0189
Trichomonas vaginalis glucosylceramidase, putative 0.0292 0.0815 0.2841
Leishmania major importin beta-1 subunit, putative 0.0151 0.0392 0.1017
Brugia malayi Nuclear hormone receptor-like 1 0.0042 0.0067 0.0173
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0115 0.0286 0.0742
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0042 0.0067 0.0173
Trichomonas vaginalis D-aminoacylase, putative 0.0223 0.0611 0.2129
Plasmodium falciparum ataxin-2 like protein, putative 0.0185 0.0494 0.2399
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0025 0.0015 0.004
Brugia malayi TAR-binding protein 0.0195 0.0526 0.1364
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.008 0.018 0.0963
Echinococcus multilocularis serine protein kinase ATM 0.0025 0.0015 0.0015
Echinococcus multilocularis lysine specific demethylase 5A 0.012 0.03 0.03
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0015 0.0053
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0041 0.0065 0.011
Onchocerca volvulus Huntingtin homolog 0.014 0.036 0.1255
Brugia malayi Steroid receptor seven-up type 2 0.0042 0.0067 0.0173
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0115 0.0286 0.0486
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0061 0.0123 0.043
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0059 0.0117 0.0304
Echinococcus multilocularis FTZ F1 alpha 0.0042 0.0067 0.0067
Entamoeba histolytica hypothetical protein 0.0305 0.0854 1
Mycobacterium tuberculosis Probable oxidoreductase 0.0142 0.0365 0.0865
Trypanosoma brucei SAM domain (Sterile alpha motif), putative 0.0027 0.0023 0.0059
Echinococcus multilocularis pdz domain containing protein 0.0027 0.0023 0.0023
Echinococcus multilocularis histone acetyltransferase myst4 0.0029 0.0027 0.0027
Brugia malayi hypothetical protein 0.0029 0.0027 0.0071
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0042 0.0067 0.0173
Mycobacterium tuberculosis Probable dehydrogenase 0.0127 0.0323 0.0764
Mycobacterium tuberculosis Probable lipase LipE 0.0223 0.0611 0.1447
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0042 0.0067 0.0113
Schistosoma mansoni dpf3 0.0029 0.0027 0.0046
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0151 0.0392 0.1368
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0062 0.0215
Loa Loa (eye worm) hypothetical protein 0.0068 0.0146 0.0247
Plasmodium vivax glutathione reductase, putative 0.0056 0.0108 0.1771
Loa Loa (eye worm) hypothetical protein 0.0499 0.1438 0.2444
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0063 0.0107
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0115 0.0286 1
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0045 0.0076
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0806 0.2359 0.4008
Onchocerca volvulus 0.0029 0.0027 0.0095
Echinococcus granulosus mitogen activated protein kinase 0.0059 0.0117 0.0199
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0007 0.0012
Brugia malayi bicaudal-C 0.0027 0.0023 0.0059
Schistosoma mansoni lamin 0.0141 0.0364 0.0618
Brugia malayi Latrophilin receptor protein 2 0.0231 0.0634 0.1644
Trypanosoma cruzi trypanothione reductase, putative 0.0056 0.0108 0.028
Schistosoma mansoni aldehyde dehydrogenase 0.0258 0.0714 0.1212
Brugia malayi Fli-1 protein 0.026 0.0719 0.1864
Trypanosoma cruzi hypothetical protein 0.0027 0.0023 0.0059
Brugia malayi Ets-domain containing protein 0.0085 0.0197 0.0511
Toxoplasma gondii ABC1 family protein 0.0223 0.0611 0.2963
Schistosoma mansoni polyhomeotic 0.0027 0.0023 0.0039
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0067 0.0173
Echinococcus multilocularis tar DNA binding protein 0.0195 0.0526 0.0526
Loa Loa (eye worm) hypothetical protein 0.0223 0.0611 0.1038
Loa Loa (eye worm) hypothetical protein 0.0781 0.2281 0.3876
Schistosoma mansoni hypothetical protein 0.0027 0.0023 0.0039
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0042 0.0067 0.0113
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0049 0.0087 0.0148
Schistosoma mansoni tar DNA-binding protein 0.0195 0.0526 0.0894
Echinococcus granulosus GA binding protein alpha chain 0.0085 0.0197 0.0335
Echinococcus granulosus sterile alpha and tir motif containing protein 0.0027 0.0023 0.0039
Brugia malayi photoreceptor-specific nuclear receptor 0.0042 0.0067 0.0173
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0035 0.0045 0.0076
Mycobacterium ulcerans aldehyde dehydrogenase 0.0258 0.0714 1
Loa Loa (eye worm) MBCTL1 0.0157 0.041 0.0697
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0059 0.0117 0.0304
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0305 0.0854 0.1452
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0043 0.0151
Echinococcus granulosus cpg binding protein 0.0207 0.0561 0.0954
Echinococcus granulosus FTZ F1 alpha 0.0042 0.0067 0.0113
Onchocerca volvulus 0.0178 0.0475 0.1656
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0035 0.0045 0.0076
Loa Loa (eye worm) latrophilin receptor protein 2 0.0231 0.0634 0.1077
Trypanosoma cruzi DNA polymerase kappa, putative 0.0061 0.0123 0.032
Brugia malayi CHD4 protein 0.0041 0.0065 0.0168
Echinococcus multilocularis importin subunit beta 1 0.0186 0.0498 0.0498
Echinococcus granulosus histone acetyltransferase myst4 0.0029 0.0027 0.0046
Schistosoma mansoni hypothetical protein 0.0029 0.0027 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0062 0.0215
Leishmania major trypanothione reductase 0.0056 0.0108 0.028
Brugia malayi mbt repeat family protein 0.0346 0.098 0.254
Onchocerca volvulus 0.0223 0.0611 0.2129
Loa Loa (eye worm) histone methyltransferase 0.006 0.012 0.0203
Schistosoma mansoni cpg binding protein 0.0207 0.0561 0.0954
Mycobacterium ulcerans transglutaminase family protein 0.007 0.015 0.0451
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0041 0.0065 0.0065
Schistosoma mansoni inositol transporter 0.0086 0.0199 0.0338
Plasmodium vivax hypothetical protein, conserved 0.002 0.0002 0.0033
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0035 0.0045 0.0116
Echinococcus granulosus sodium:glucose cotransporter 2 0.0086 0.0199 0.0338
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0124 0.0311 0.0311
Echinococcus granulosus phd finger protein 12 0.0029 0.0027 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0062 0.0215
Onchocerca volvulus 0.002 0 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0042 0.0067 0.0173
Trypanosoma cruzi hypothetical protein, conserved 0.0223 0.0611 0.1584
Loa Loa (eye worm) hypothetical protein 0.0223 0.0611 0.1038
Loa Loa (eye worm) inositol-1 0.008 0.018 0.0306
Trichomonas vaginalis ap endonuclease, putative 0.0098 0.0234 0.0816
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0098 0.0234 0.0607
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0046
Trypanosoma brucei DNA polymerase IV, putative 0.0061 0.0123 0.032
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0117 0.0408
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.1306 0.3856 1
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0223 0.0611 0.1447
Trypanosoma cruzi Kinesin-13 5, putative 0.0027 0.0023 0.0059
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0027 0.0046
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0053 0.0099 0.0346
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0117 0.0408
Trypanosoma brucei DNA polymerase IV, putative 0.0061 0.0123 0.032
Schistosoma mansoni Protein aveugle 0.0027 0.0023 0.0039
Echinococcus granulosus pdz domain containing protein 0.0027 0.0023 0.0039
Echinococcus granulosus polyhomeotic protein 2 0.0027 0.0023 0.0039
Giardia lamblia DINP protein human, muc B family 0.0061 0.0123 0.431
Plasmodium vivax importin-beta 2, putative 0.0186 0.0498 0.8148
Trypanosoma cruzi DNA polymerase kappa, putative 0.0061 0.0123 0.032
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0067 0.0173
Schistosoma mansoni inositol monophosphatase 0.008 0.018 0.0306
Brugia malayi Bromodomain containing protein 0.0032 0.0035 0.0092
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0035 0.0045 0.0156
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0035 0.0045 0.0076
Echinococcus granulosus serine protein kinase ATM 0.0025 0.0015 0.0026
Trypanosoma cruzi PAB1-binding protein , putative 0.0185 0.0494 0.1282
Schistosoma mansoni hypothetical protein 0.0231 0.0634 0.1077
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0123 0.032
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0707 0.2061 0.3502
Onchocerca volvulus 0.0223 0.0611 0.2129
Mycobacterium tuberculosis Hypothetical protein 0.007 0.015 0.0355
Mycobacterium ulcerans esterase/lipase LipP 0.0223 0.0611 0.8257
Echinococcus granulosus carbonic anhydrase II 0.1306 0.3856 0.6552
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0029 0.0139
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0123 0.032
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0098 0.0234 0.1136
Schistosoma mansoni GTP-binding protein alpha subunit 0.0035 0.0045 0.0076
Echinococcus granulosus tumor suppressor p53 binding protein 1 0.0356 0.1007 0.171
Onchocerca volvulus 0.0042 0.0067 0.0232
Brugia malayi RNA binding protein 0.0195 0.0526 0.1364
Schistosoma mansoni importin beta-1 0.0186 0.0498 0.0846
Trypanosoma cruzi PAB1-binding protein , putative 0.0185 0.0494 0.1282
Trichomonas vaginalis ran, putative 0.0115 0.0286 0.0998
Onchocerca volvulus 0.0035 0.0045 0.0156
Onchocerca volvulus Protein ultraspiracle homolog 0.0042 0.0067 0.0232
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0035 0.0045 0.0116
Loa Loa (eye worm) hypothetical protein 0.0027 0.0023 0.0039
Trichomonas vaginalis glucosylceramidase, putative 0.0292 0.0815 0.2841
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0731 0.2131 0.5527
Loa Loa (eye worm) hypothetical protein 0.0707 0.2061 0.3502
Loa Loa (eye worm) hypothetical protein 0.0035 0.0045 0.0076
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0223 0.0611 0.1038
Schistosoma mansoni ap endonuclease 0.0098 0.0234 0.0398
Echinococcus multilocularis lysine specific demethylase 5B 0.0029 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0231 0.0634 0.1077
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0042 0.0067 0.0173
Echinococcus multilocularis uro adherence factor A 0.0029 0.0027 0.0027
Onchocerca volvulus 0.0139 0.0357 0.1246
Echinococcus granulosus liprin alpha 2 0.0027 0.0023 0.0039
Trichomonas vaginalis DNA polymerase eta, putative 0.0061 0.0123 0.043
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0035 0.0045 0.0076
Echinococcus multilocularis polycomb protein SCMH1 0.0335 0.0944 0.0944
Echinococcus multilocularis importin 5 0.0035 0.0046 0.0046
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0258 0.0714 0.1691
Brugia malayi Thioredoxin reductase 0.0056 0.0108 0.028
Giardia lamblia Hypothetical protein 0.007 0.015 0.5241
Loa Loa (eye worm) hypothetical protein 0.0707 0.2061 0.3502
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0027 0.0133
Loa Loa (eye worm) hypothetical protein 0.0035 0.0045 0.0076
Mycobacterium tuberculosis Conserved protein 0.0223 0.0611 0.1447
Onchocerca volvulus 0.0035 0.0045 0.0156
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0042 0.0067 0.0173
Trypanosoma cruzi DNA polymerase eta, putative 0.0061 0.0123 0.032
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0035 0.0045 0.0045
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.006 0.012 0.012
Onchocerca volvulus 0.0141 0.0364 0.1267
Schistosoma mansoni zinc finger protein 0.0029 0.0027 0.0046
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0707 0.2061 0.5345
Leishmania major hypothetical protein, conserved 0.0223 0.0611 0.1584
Echinococcus multilocularis cpg binding protein 0.0207 0.0561 0.0561
Onchocerca volvulus 0.0035 0.0045 0.0156
Brugia malayi SET domain containing protein 0.0021 0.0003 0.0009
Toxoplasma gondii hypothetical protein 0.0028 0.0024 0.0117
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0035 0.0045 0.0045
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0042 0.0067 0.0113
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.002 0.0002 0.001
Plasmodium vivax SET domain protein, putative 0.0126 0.032 0.5238
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0053 0.0099 0.0346
Echinococcus multilocularis geminin 0.1626 0.4815 0.4815
Brugia malayi SET domain containing protein 0.0037 0.0053 0.0136
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0115 0.0286 0.1389
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.008 0.018 0.0467
Echinococcus multilocularis remodeling and spacing factor 1 0.0029 0.0027 0.0027
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0053 0.0099 0.0346
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0382 0.1087 0.1847
Toxoplasma gondii HEAT repeat-containing protein 0.0186 0.0498 0.2415
Plasmodium falciparum thioredoxin reductase 0.0056 0.0108 0.0525
Brugia malayi PHD-finger family protein 0.0029 0.0027 0.0071
Toxoplasma gondii thioredoxin reductase 0.0056 0.0108 0.0525
Schistosoma mansoni nuclear hormone receptor 0.0042 0.0067 0.0113
Onchocerca volvulus Bile acid receptor homolog 0.0042 0.0067 0.0232
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0035 0.0045 0.0045
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0142 0.0365 0.4669
Mycobacterium leprae conserved hypothetical protein 0.0223 0.0611 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0045 0.0076
Echinococcus granulosus dna polymerase eta 0.0061 0.0123 0.021
Mycobacterium tuberculosis Conserved protein 0.0223 0.0611 0.1447
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0035 0.0045 0.0076
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0059 0.0117 0.0304
Schistosoma mansoni steroid hormone receptor ad4bp 0.0042 0.0067 0.0113
Echinococcus granulosus carbonic anhydrase 0.0707 0.2061 0.3502
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0076 0.0167 0.0284
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.0297 0.0505
Trypanosoma brucei carbonic anhydrase-like protein 0.1306 0.3856 1
Echinococcus multilocularis PHD and RING finger domain containing protein 1 0.0029 0.0027 0.0027
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0086 0.0199 0.0199
Echinococcus granulosus Sterile alpha motif SAM 0.0027 0.0023 0.0039
Loa Loa (eye worm) hypothetical protein 0.0061 0.0123 0.021
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0035 0.0045 0.0116
Schistosoma mansoni hypothetical protein 0.0356 0.1007 0.171
Trichomonas vaginalis glucosylceramidase, putative 0.0202 0.0545 0.1901
Trypanosoma brucei unspecified product 0.0061 0.0123 0.032
Echinococcus multilocularis dna polymerase kappa 0.0061 0.0123 0.0123
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.008 0.018 0.0874
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.0297 0.0505
Echinococcus multilocularis dna polymerase eta 0.0061 0.0123 0.0123
Giardia lamblia PHD finger protein 15 0.0029 0.0029 0.0998
Plasmodium falciparum glutathione reductase 0.0056 0.0108 0.0525
Brugia malayi hypothetical protein 0.0022 0.0007 0.0019
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0071 0.0155 0.0367
Echinococcus multilocularis tumor suppressor p53 binding protein 1 0.0356 0.1007 0.1007
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0049 0.0087 0.0087
Echinococcus granulosus dna polymerase kappa 0.0061 0.0123 0.021
Brugia malayi PHD-finger family protein 0.0051 0.0094 0.0244
Echinococcus multilocularis phd finger protein 10 0.0029 0.0027 0.0027
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0059 0.0117 0.0304
Brugia malayi ImpB/MucB/SamB family protein 0.0061 0.0123 0.032
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0029 0.0049
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0127 0.0323 0.0764
Loa Loa (eye worm) TAR-binding protein 0.0195 0.0526 0.0894
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0102 0.0247 0.064
Echinococcus granulosus SAM and MBT domain containing protein 0.0464 0.1332 0.2264
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0042 0.0067 0.0113
Brugia malayi hypothetical protein 0.0028 0.0023 0.0061
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0083 0.0189 0.0321
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0143 0.0369 0.0627
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0806 0.2359 0.2359
Loa Loa (eye worm) hypothetical protein 0.0022 0.0007 0.0012
Schistosoma mansoni high-affinity choline transporter 0.0781 0.2281 0.3876
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0151 0.0392 0.1368
Brugia malayi hypothetical protein 0.014 0.036 0.0934
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.0514 0.1793
Echinococcus granulosus snurportin 1 0.1983 0.5885 1
Trichomonas vaginalis glucosylceramidase, putative 0.0202 0.0545 0.1901
Schistosoma mansoni Protein orai-1 0.0927 0.2721 0.4624
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0042 0.0067 0.0113
Schistosoma mansoni importin-beta 2 0.0035 0.0046 0.0078
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0145 0.0377 0.0377
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0046
Toxoplasma gondii hypothetical protein 0.0707 0.2061 1
Echinococcus granulosus lamin 0.0141 0.0364 0.0618
Schistosoma mansoni sex comb on midleg homolog 0.0335 0.0944 0.1605
Schistosoma mansoni ap endonuclease 0.0098 0.0234 0.0398
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.006 0.012 0.0203
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0707 0.2061 0.5345
Schistosoma mansoni inositol transporter 0.0086 0.0199 0.0338
Schistosoma mansoni hypothetical protein 0.1232 0.3633 0.6173
Loa Loa (eye worm) hypothetical protein 0.0223 0.0611 0.1038
Schistosoma mansoni retinoic acid receptor RXR 0.0042 0.0067 0.0113
Onchocerca volvulus 0.0037 0.0053 0.0183
Schistosoma mansoni transcription factor LCR-F1 0.0305 0.0854 0.1452
Echinococcus granulosus dnaJ subfamily B 0.1265 0.3732 0.6341
Trichomonas vaginalis hypothetical protein 0.0022 0.0006 0.002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0143 0.0369 0.0627
Schistosoma mansoni carbonic anhydrase-related 0.0707 0.2061 0.3502
Loa Loa (eye worm) hypothetical protein 0.0068 0.0145 0.0246
Leishmania major GTP-binding protein, putative 0.0115 0.0286 0.0742
Brugia malayi Bromodomain containing protein 0.0099 0.0239 0.062
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0042 0.0067 0.0113
Loa Loa (eye worm) toll and interleukin 1 receptor domain-containing protein isoform f 0.0027 0.0023 0.0039
Toxoplasma gondii FATC domain-containing protein 0.0025 0.0015 0.0074
Echinococcus multilocularis phd finger protein 12 0.0029 0.0027 0.0027
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0042 0.0067 0.0173
Loa Loa (eye worm) hypothetical protein 0.0028 0.0023 0.004
Loa Loa (eye worm) hypothetical protein 0.014 0.036 0.0612
Brugia malayi Thioredoxin family protein 0.007 0.015 0.0389
Loa Loa (eye worm) hypothetical protein 0.0058 0.0113 0.0193
Mycobacterium ulcerans aldehyde dehydrogenase 0.0258 0.0714 1
Toxoplasma gondii HEAT repeat-containing protein 0.0035 0.0046 0.0224
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0123 0.032
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0068 0.0145 0.0246
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.0514 0.1793
Echinococcus multilocularis snurportin 1 0.1983 0.5885 0.5885
Onchocerca volvulus 0.0029 0.0027 0.0095
Plasmodium falciparum phd finger protein, putative 0.0029 0.0029 0.0139
Echinococcus granulosus geminin 0.1626 0.4815 0.8181
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0042 0.0067 0.0173
Schistosoma mansoni inositol monophosphatase 0.008 0.018 0.0306
Loa Loa (eye worm) hypothetical protein 0.0039 0.0059 0.01
Echinococcus granulosus Sterile alpha motif type 0.0027 0.0023 0.0039
Loa Loa (eye worm) F/Y-rich family protein 0.0029 0.0027 0.0046
Trypanosoma cruzi DNA polymerase kappa, putative 0.0061 0.0123 0.032
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0035 0.0045 0.0156
Mycobacterium tuberculosis Conserved protein 0.007 0.015 0.0355
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0858 0.2514 0.4272
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0062 0.0215
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0042 0.0067 0.0113
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0042 0.0067 0.0113
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0071 0.0155 0.0111
Echinococcus multilocularis peregrin 0.0032 0.0035 0.0035
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0098 0.0234 0.818
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0292 0.0815 0.1384
Brugia malayi hypothetical protein 0.0119 0.0298 0.0773
Schistosoma mansoni carbonic anhydrase-related 0.0707 0.2061 0.3502
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0098 0.0234 0.0607
Schistosoma mansoni hypothetical protein 0.0029 0.0027 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0027 0.0095
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0768 0.2242 0.2242
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0035 0.0045 0.0156
Brugia malayi hypothetical protein 0.0927 0.2721 0.7058
Loa Loa (eye worm) hypothetical protein 0.0042 0.0067 0.0113
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0025 0.0015 0.0026
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0157 0.041 0.041
Onchocerca volvulus 0.007 0.015 0.0523
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0042 0.0067 0.0113
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0123 0.032
Brugia malayi kap beta 3 protein 0.0035 0.0046 0.012
Echinococcus granulosus peregrin 0.0032 0.0035 0.006
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0042 0.0067 0.0113
Schistosoma mansoni PHD zinc finger protein XAP135-related 0.0029 0.0027 0.0046
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0046
Schistosoma mansoni hypothetical protein 0.0231 0.0634 0.1077
Brugia malayi ecdysteroid receptor 0.0042 0.0067 0.0173
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.0514 0.1793
Brugia malayi hypothetical protein 0.0035 0.0045 0.0116
Brugia malayi MH2 domain containing protein 0.0119 0.0297 0.0771
Echinococcus multilocularis chromobox protein 2 0.0214 0.0583 0.0583
Trypanosoma cruzi DNA polymerase kappa, putative 0.0061 0.0123 0.032
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.002 0 0.0001
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0223 0.0611 0.1038
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0098 0.0234 0.0398
Echinococcus granulosus tar DNA binding protein 0.0195 0.0526 0.0894
Schistosoma mansoni hypothetical protein 0.0499 0.1438 0.2444
Schistosoma mansoni terminal deoxycytidyl transferase 0.0061 0.0123 0.021
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.008 0.018 0.0467
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0046
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0035 0.0045 0.0076
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0062 0.0215
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.1306 0.3856 0.6552
Loa Loa (eye worm) G protein alpha subunit 3 0.0035 0.0045 0.0076
Loa Loa (eye worm) glutathione reductase 0.0056 0.0108 0.0184
Schistosoma mansoni spingomyelin synthetase-related 0.0027 0.0023 0.0039
Brugia malayi RNA recognition motif domain containing protein 0.0195 0.0526 0.1364
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0117 0.0199
Schistosoma mansoni mixed-lineage leukemia protein mll 0.003 0.0031 0.0053
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0122 0.0207
Echinococcus granulosus histone lysine methyltransferase setb 0.0143 0.0369 0.0627
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0142 0.0365 0.0865
Schistosoma mansoni thyroid hormone receptor 0.0042 0.0067 0.0113
Brugia malayi Sphingomyelin synthase-related 1 0.0027 0.0023 0.0059
Trichomonas vaginalis set domain proteins, putative 0.0976 0.2868 1
Echinococcus multilocularis translational activator gcn1 0.0035 0.0046 0.0046
Echinococcus multilocularis carbonic anhydrase 0.0707 0.2061 0.2061
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0046
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0085 0.0195 0.0331
Trypanosoma brucei protein kinase, putative 0.0059 0.0117 0.0304
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0046
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0056 0.0108 0.0256
Brugia malayi nuclear receptor NHR-88 0.0042 0.0067 0.0173
Onchocerca volvulus 0.0223 0.0611 0.2129
Echinococcus granulosus ecdysone induced protein 78C 0.0042 0.0067 0.0113
Schistosoma mansoni hypothetical protein 0.0029 0.0027 0.0046
Trichomonas vaginalis D-aminoacylase, putative 0.0223 0.0611 0.2129
Loa Loa (eye worm) hypothetical protein 0.0141 0.0364 0.0618
Plasmodium vivax hypothetical protein, conserved 0.0223 0.0611 1
Mycobacterium tuberculosis Probable esterase LipL 0.0223 0.0611 0.1447
Loa Loa (eye worm) importin-beta domain-containing protein 0.0035 0.0046 0.0078
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0049 0.0087 0.0087
Brugia malayi cask-interacting protein 2 0.0027 0.0023 0.0059
Schistosoma mansoni DNAj-like protein 0.0027 0.0023 0.0039
Loa Loa (eye worm) CHromoDomain protein family member 0.0041 0.0065 0.011
Trypanosoma brucei importin beta-1 subunit, putative 0.0186 0.0498 0.1291
Loa Loa (eye worm) hypothetical protein 0.0186 0.0498 0.0846
Echinococcus multilocularis thioredoxin glutathione reductase 0.0056 0.0108 0.0108
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0042 0.0067 0.0067
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0035 0.0045 0.0116
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0035 0.0045 0.0076
Loa Loa (eye worm) hypothetical protein 0.0138 0.0356 0.0605
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0027 0.0095
Schistosoma mansoni aldehyde dehydrogenase 0.0258 0.0714 0.1212
Toxoplasma gondii HEAT repeat-containing protein 0.0035 0.0046 0.0224
Trichomonas vaginalis glucosylceramidase, putative 0.0292 0.0815 0.2841
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0127 0.0323 0.0764
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0035 0.0045 0.0156
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0223 0.0611 0.1447
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0035 0.0045 0.0076
Brugia malayi RNA, U transporter 1 0.0528 0.1524 0.3953
Schistosoma mansoni myelin transcription factor 1 myt1 0.0157 0.041 0.0697
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0042 0.0067 0.0173
Loa Loa (eye worm) hypothetical protein 0.0042 0.0067 0.0113
Brugia malayi hypothetical protein 0.0305 0.0854 0.2216
Echinococcus granulosus lysine specific demethylase 5A 0.0149 0.0386 0.0656
Loa Loa (eye worm) carbonic anhydrase 3 0.1306 0.3856 0.6552
Schistosoma mansoni ran 0.0115 0.0286 0.0486
Schistosoma mansoni zinc finger protein 0.0029 0.0027 0.0046
Echinococcus multilocularis carbonic anhydrase 0.0707 0.2061 0.2061
Schistosoma mansoni hypothetical protein 0.0029 0.0029 0.0049
Schistosoma mansoni jumonji domain containing protein 0.0104 0.0252 0.0428
Echinococcus granulosus intermediate filament protein 0.0141 0.0364 0.0618
Echinococcus granulosus carbonic anhydrase 0.0707 0.2061 0.3502
Echinococcus granulosus sphingomyelin synthase protein 1 0.0027 0.0023 0.0039
Schistosoma mansoni hypothetical protein 0.1265 0.3732 0.6341
Brugia malayi hypothetical protein 0.05 0.1441 0.3737
Onchocerca volvulus Alhambra homolog 0.0029 0.0029 0.01
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0035 0.0045 0.0076
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0806 0.2359 0.6117
Echinococcus granulosus survival motor neuron protein 1 0.05 0.1441 0.2448
Echinococcus granulosus expressed protein 0.0035 0.0045 0.0076
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0126 0.032 0.032
Trichomonas vaginalis penicillin-binding protein, putative 0.0223 0.0611 0.2129
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0098 0.0234 0.274
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0292 0.0815 0.2113
Loa Loa (eye worm) intermediate filament protein 0.0141 0.0364 0.0618
Loa Loa (eye worm) CXXC zinc finger family protein 0.0178 0.0475 0.0807
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0027 0.0095
Echinococcus multilocularis liprin alpha 2 0.0027 0.0023 0.0023
Trichomonas vaginalis glucosylceramidase, putative 0.0292 0.0815 0.2841
Trichomonas vaginalis D-aminoacylase, putative 0.0223 0.0611 0.2129
Schistosoma mansoni hypothetical protein 0.007 0.015 0.0255
Loa Loa (eye worm) hypothetical protein 0.05 0.1441 0.2448
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0223 0.0611 0.8257
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0036 0.0048 0.0124
Echinococcus granulosus polyhomeotic proximal chromatin protein 0.0027 0.0023 0.0039
Loa Loa (eye worm) hypothetical protein 0.0042 0.0067 0.0113
Trypanosoma brucei hypothetical protein, conserved 0.0223 0.0611 0.1584
Loa Loa (eye worm) thioredoxin reductase 0.0056 0.0108 0.0184
Loa Loa (eye worm) hypothetical protein 0.0068 0.0145 0.0247
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0707 0.2061 0.5345
Echinococcus granulosus GPCR family 2 0.0231 0.0634 0.1077
Plasmodium falciparum carbonic anhydrase 0.0707 0.2061 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0046
Mycobacterium ulcerans beta-lactamase 0.0223 0.0611 0.8257
Echinococcus granulosus TAF3 RNA polymerase II TATA box binding protein 0.0029 0.0027 0.0046
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0117 0.0408
Mycobacterium tuberculosis Probable reductase 0.0127 0.0323 0.0764
Loa Loa (eye worm) hypothetical protein 0.0038 0.0056 0.0095
Trichomonas vaginalis myo inositol monophosphatase, putative 0.008 0.018 0.0628
Loa Loa (eye worm) hypothetical protein 0.0029 0.0029 0.0049
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0098 0.0234 0.0607
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0223 0.0611 0.1038
Brugia malayi MAP kinase sur-1 0.0059 0.0117 0.0304
Echinococcus multilocularis solute carrier family 5 0.0086 0.0199 0.0199
Loa Loa (eye worm) hypothetical protein 0.0027 0.0023 0.0039
Schistosoma mansoni phd finger protein 0.0056 0.0109 0.0186
Schistosoma mansoni fyve-containing 0.0029 0.0027 0.0046
Brugia malayi Importin beta-1 subunit 0.0186 0.0498 0.1291
Loa Loa (eye worm) hypothetical protein 0.0035 0.0045 0.0076
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0085 0.0197 0.0335
Plasmodium falciparum zinc finger protein, putative 0.004 0.006 0.0291
Mycobacterium ulcerans hypothetical protein 0.007 0.015 0.0451
Loa Loa (eye worm) hypothetical protein 0.0042 0.0067 0.0113
Brugia malayi exodeoxyribonuclease III family protein 0.0098 0.0234 0.0607
Onchocerca volvulus 0.0027 0.0023 0.008
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0157 0.041 0.1064
Schistosoma mansoni hypothetical protein 0.1626 0.4815 0.8181
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0543 0.1568 0.5466
Mycobacterium tuberculosis Conserved hypothetical protein 0.007 0.015 0.0355
Echinococcus multilocularis transportin 1 0.0035 0.0046 0.0046
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0059 0.0117 0.0304
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0123 0.032
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0058 0.0116 0.0197
Toxoplasma gondii AP2 domain transcription factor AP2VIIa-7 0.0029 0.0027 0.0133
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0027 0.0046
Echinococcus granulosus importin 5 0.0035 0.0046 0.0078
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0035 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0027 0.0023 0.0039
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0035 0.0045 0.0156
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0053 0.0099 0.0346
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0029 0.0029
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0059 0.0117 0.0304
Leishmania major carbonic anhydrase-like protein 0.1306 0.3856 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0231 0.0634 0.0634
Plasmodium vivax JmjC domain containing protein 0.0041 0.0064 0.1045
Echinococcus multilocularis polyhomeotic protein 2 0.0027 0.0023 0.0023
Loa Loa (eye worm) RNA binding protein 0.0195 0.0526 0.0894
Loa Loa (eye worm) hypothetical protein 0.0042 0.0067 0.0113
Plasmodium falciparum transportin 0.0035 0.0046 0.0224
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0258 0.0714 0.1212
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0029 0.0139
Giardia lamblia Giardia trophozoite antigen GTA-1 0.0027 0.0023 0.08
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0061 0.0123 0.0292
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0223 0.0611 0.1447
Leishmania major DNA polymerase kappa, putative 0.0061 0.0123 0.032
Echinococcus multilocularis sphingomyelin synthase protein 1 0.0027 0.0023 0.0023
Entamoeba histolytica hypothetical protein 0.0025 0.0015 0.0179
Toxoplasma gondii LsmAD domain-containing protein 0.0185 0.0494 0.2399
Loa Loa (eye worm) kap beta 3 protein 0.0035 0.0046 0.0078
Onchocerca volvulus 0.0147 0.038 0.1326
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0053 0.0099 0.0346
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0035 0.0045 0.0076
Trypanosoma cruzi importin beta-1 subunit, putative 0.0151 0.0392 0.1017
Echinococcus granulosus lysine specific demethylase 5B 0.0029 0.0027 0.0046
Schistosoma mansoni tar DNA-binding protein 0.0195 0.0526 0.0894
Echinococcus granulosus Zinc finger DBF type 0.0029 0.0027 0.0046
Schistosoma mansoni hypothetical protein 0.1626 0.4815 0.8181
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0059 0.0117 0.0304
Echinococcus multilocularis TAF3 RNA polymerase II, TATA box binding protein 0.0029 0.0027 0.0027
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0127 0.0323 0.0764
Echinococcus multilocularis thyroid hormone receptor alpha 0.0042 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0927 0.2721 0.4624
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0042 0.0067 0.0113
Entamoeba histolytica hypothetical protein 0.004 0.006 0.0701
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.008 0.018 0.0467
Loa Loa (eye worm) beta-lactamase 0.0223 0.0611 0.1038
Trypanosoma brucei DNA polymerase IV, putative 0.0061 0.0123 0.032
Schistosoma mansoni hypothetical protein 0.0707 0.2061 0.3502
Echinococcus granulosus remodeling and spacing factor 1 0.0029 0.0027 0.0046
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.1983 0.5885 1
Echinococcus granulosus zinc finger protein 0.0046 0.0078 0.0133
Loa Loa (eye worm) hypothetical protein 0.0086 0.0199 0.0338
Schistosoma mansoni GTP-binding protein alpha subunit 0.0035 0.0045 0.0076
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0042 0.0067 0.0113
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0049 0.0087 0.0087
Brugia malayi PHD-finger family protein 0.0029 0.0027 0.0071
Loa Loa (eye worm) hypothetical protein 0.0027 0.0023 0.0039
Toxoplasma gondii exonuclease III APE 0.0098 0.0234 0.1136
Brugia malayi GH02984p 0.0781 0.2281 0.5915
Echinococcus multilocularis dnaJ subfamily B 0.1265 0.3732 0.3732
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0061 0.0123 0.032
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0042 0.0067 0.0173
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0181 0.0484 0.1688
Loa Loa (eye worm) hypothetical protein 0.0143 0.0369 0.0627
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0305 0.0854 0.0854
Trypanosoma cruzi Ring finger domain/PHD-finger, putative 0.0029 0.0027 0.0071
Brugia malayi hypothetical protein 0.0027 0.0023 0.0059
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0138 0.0353 0.1715
Trypanosoma cruzi Ring finger domain/PHD-finger, putative 0.0029 0.0027 0.0071
Echinococcus multilocularis Sterile alpha motif SAM 0.0027 0.0023 0.0023
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.0514 0.1793
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0035 0.0045 0.0076
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0098 0.0234 0.0398
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0231 0.0634 0.0634
Brugia malayi F/Y-rich N-terminus family protein 0.0087 0.0202 0.0524
Brugia malayi latrophilin 2 splice variant baaae 0.0499 0.1438 0.373
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.1306 0.3856 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1428 0.4221 1
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0029 0.0049
Onchocerca volvulus 0.0374 0.1062 0.3701
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0063 0.0063
Onchocerca volvulus Tankyrase homolog 0.0027 0.0023 0.008
Brugia malayi olfactory channel protein osm-9 0.0065 0.0137 0.0355
Loa Loa (eye worm) hypothetical protein 0.0223 0.0611 0.1038
Trypanosoma brucei unspecified product 0.0042 0.0067 0.0173
Brugia malayi hypothetical protein 0.0029 0.0027 0.0071
Brugia malayi mbt repeat family protein 0.0543 0.1568 0.4066
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0027 0.0095
Echinococcus granulosus lamin dm0 0.0141 0.0364 0.0618
Brugia malayi beta-lactamase 0.0223 0.0611 0.1584
Leishmania major DNA polymerase eta, putative 0.0061 0.0123 0.032
Schistosoma mansoni tar DNA-binding protein 0.0195 0.0526 0.0894
Schistosoma mansoni lamin 0.0141 0.0364 0.0618
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0806 0.2359 0.2359
Trypanosoma brucei importin beta-1 subunit, putative 0.0186 0.0498 0.1291
Leishmania major hypothetical protein, conserved 0.0035 0.0046 0.012
Loa Loa (eye worm) hypothetical protein 0.0042 0.0067 0.0113
Schistosoma mansoni ets-related 0.026 0.0719 0.1221
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0118 0.0295 0.0501
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0086 0.0199 0.0338
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0231 0.0634 0.1077
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0806 0.2359 0.4008
Entamoeba histolytica hypothetical protein 0.0305 0.0854 1
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0061 0.0123 0.021
Treponema pallidum exodeoxyribonuclease (exoA) 0.0098 0.0234 1
Trichomonas vaginalis c2h2 zinc finger protein, putative 0.0027 0.0023 0.008
Loa Loa (eye worm) hypothetical protein 0.0185 0.0494 0.084
Loa Loa (eye worm) tnks protein 0.0028 0.0023 0.004
Mycobacterium tuberculosis Conserved protein 0.0223 0.0611 0.1447
Loa Loa (eye worm) hypothetical protein 0.0027 0.0023 0.0039
Trichomonas vaginalis penicillin-binding protein, putative 0.0223 0.0611 0.2129
Trypanosoma brucei trypanothione reductase 0.0056 0.0108 0.028
Trichomonas vaginalis glucosylceramidase, putative 0.0292 0.0815 0.2841
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0707 0.2061 0.5345
Trichomonas vaginalis inhibitor of growth, putative 0.0029 0.0027 0.0095
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0806 0.2359 0.4008
Echinococcus multilocularis expressed protein 0.0035 0.0045 0.0045
Schistosoma mansoni tar DNA-binding protein 0.0195 0.0526 0.0894
Schistosoma mansoni myst histone acetyltransferase 0.0029 0.0027 0.0046
Plasmodium falciparum ataxin-2 like protein, putative 0.0185 0.0494 0.2399
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0027 0.0095
Schistosoma mansoni carbonic anhydrase 0.0707 0.2061 0.3502
Loa Loa (eye worm) hypothetical protein 0.0223 0.0611 0.1038
Loa Loa (eye worm) hypothetical protein 0.014 0.036 0.0612
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.1306 0.3856 1
Entamoeba histolytica hypothetical protein 0.0305 0.0854 1
Schistosoma mansoni lar interacting protein (lip)-related protein 0.0027 0.0023 0.0039
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0029 0.0027 0.0046
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0123 0.032
Echinococcus granulosus histone acetyltransferase MYST2 0.0157 0.041 0.0697
Trichomonas vaginalis hypothetical protein 0.0035 0.0046 0.0161
Entamoeba histolytica HEAT repeat domain containing protein 0.0035 0.0046 0.054
Loa Loa (eye worm) hypothetical protein 0.0065 0.0137 0.0233
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.1306 0.3856 0.6552
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0059 0.0117 0.0199
Echinococcus granulosus high affinity choline transporter 1 0.0781 0.2281 0.3876
Schistosoma mansoni cpg binding protein 0.0178 0.0475 0.0807
Loa Loa (eye worm) hypothetical protein 0.0021 0.0005 0.0008
Echinococcus multilocularis sterile alpha and tir motif containing protein 0.0027 0.0023 0.0023
Loa Loa (eye worm) fli-1 protein 0.026 0.0719 0.1221
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0022 0.0007 0.0012
Schistosoma mansoni sex comb on midleg homolog 0.0335 0.0944 0.1605
Plasmodium falciparum EELM2 domain-containing protein, putative 0.0029 0.0027 0.0133
Echinococcus granulosus fetal alzheimer antigen falz 0.0049 0.0087 0.0148
Entamoeba histolytica G protein alpha subunit, putative 0.0035 0.0045 0.0522
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0042 0.0067 0.0113
Echinococcus multilocularis lamin 0.0141 0.0364 0.0364
Brugia malayi Pre-SET motif family protein 0.0126 0.032 0.083
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0098 0.0234 0.3833
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0115 0.0286 0.0742
Brugia malayi CXXC zinc finger family protein 0.0178 0.0475 0.1232
Brugia malayi sterile alpha and TIR motif containing protein 1 isoform a 0.0027 0.0023 0.0059
Brugia malayi hypothetical protein 0.0147 0.038 0.0987
Brugia malayi Inositol-1 0.008 0.018 0.0467
Mycobacterium tuberculosis Conserved hypothetical protein 0.0061 0.0123 0.0292
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0042 0.0067 0.0113
Echinococcus multilocularis carbonic anhydrase 0.0707 0.2061 0.2061
Schistosoma mansoni hypothetical protein 0.1983 0.5885 1
Trichomonas vaginalis ap endonuclease, putative 0.0098 0.0234 0.0816
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0768 0.2242 0.381
Plasmodium falciparum JmjC domain-containing protein, putative 0.0041 0.0064 0.031
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0029 0.0027 0.0027
Schistosoma mansoni phd finger protein 0.0029 0.0027 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0062 0.0215
Trichomonas vaginalis helicase, putative 0.004 0.0062 0.0215
Echinococcus granulosus inositol monophosphatase 1 0.008 0.018 0.0306
Schistosoma mansoni SET domain protein 0.0037 0.0053 0.0089
Plasmodium vivax thioredoxin reductase, putative 0.0056 0.0108 0.1771
Brugia malayi intermediate filament protein 0.0141 0.0364 0.0943
Entamoeba histolytica myo-inositol monophosphatase, putative 0.008 0.018 0.2109
Plasmodium falciparum importin beta, putative 0.0186 0.0498 0.2415
Echinococcus multilocularis carbonic anhydrase II 0.1306 0.3856 0.3856
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.0514 0.1793
Schistosoma mansoni hypothetical protein 0.0102 0.0247 0.0419
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0223 0.0611 0.1584
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0464 0.1332 0.2264
Schistosoma mansoni hypothetical protein 0.0305 0.0854 0.1452
Echinococcus multilocularis SAM and MBT domain containing protein 0.0464 0.1332 0.1332
Schistosoma mansoni hypothetical protein 0.0029 0.0027 0.0046
Onchocerca volvulus 0.0027 0.0023 0.008
Toxoplasma gondii aldehyde dehydrogenase 0.0258 0.0714 0.3462
Entamoeba histolytica deoxycytidyl transferase, putative 0.0061 0.0123 0.1444
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0061 0.0123 0.021
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0195 0.0526 0.0894
Schistosoma mansoni coup transcription factor 0.0042 0.0067 0.0113
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0806 0.2359 0.4008
Toxoplasma gondii PLU-1 family protein 0.0048 0.0084 0.0407
Brugia malayi Liprin-alpha 2 0.0027 0.0023 0.0059
Brugia malayi jmjC domain containing protein 0.0124 0.0311 0.0807
Echinococcus multilocularis inositol monophosphatase 1 0.008 0.018 0.018
Echinococcus granulosus calcium release activated calcium channel 0.0927 0.2721 0.4624
Echinococcus granulosus liprin alpha 2 0.0027 0.0023 0.0039
Brugia malayi nuclear hormone receptor 0.0042 0.0067 0.0173
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.002 0 0.0001
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0086 0.0199 0.0199
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0098 0.0234 1
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0035 0.0045 0.0116
Echinococcus granulosus phd finger protein 10 0.0029 0.0027 0.0046
Echinococcus granulosus mitogen activated protein kinase 3 0.0059 0.0117 0.0199
Schistosoma mansoni Protein aveugle 0.0027 0.0023 0.0039
Brugia malayi Shank2E 0.0027 0.0023 0.0059
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0042 0.0067 0.0113
Echinococcus granulosus PHD and RING finger domain containing protein 1 0.0029 0.0027 0.0046
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0042 0.0067 0.0113
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0086 0.0199 0.0965
Schistosoma mansoni carbonic anhydrase-related 0.0707 0.2061 0.3502
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0049 0.0087 0.0148
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0035 0.0045 0.0076
Giardia lamblia Kinase, CMGC MAPK 0.0059 0.0117 0.409
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0035 0.0045 0.0156
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0053 0.0099 0.0346
Echinococcus granulosus mixed lineage leukemia protein mll 0.0049 0.0087 0.0148
Onchocerca volvulus 0.0027 0.0023 0.008
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0062 0.0215
Trichomonas vaginalis cgi-62, putative 0.0027 0.0023 0.008
Echinococcus granulosus thioredoxin glutathione reductase 0.0056 0.0108 0.0184
Schistosoma mansoni thyroid hormone receptor 0.0042 0.0067 0.0113
Schistosoma mansoni cpg binding protein 0.0207 0.0561 0.0954
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0007 0.0019
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0029 0.0049
Schistosoma mansoni requim req/dpf2 0.0029 0.0027 0.0046
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0142 0.0365 0.0865
Toxoplasma gondii SWI2/SNF2-containing PHD finger protein 0.0029 0.0027 0.0133
Brugia malayi glutathione reductase 0.0056 0.0108 0.028
Onchocerca volvulus Glucosylceramidase homolog 0.0191 0.0514 0.1793
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0117 0.0408
Schistosoma mansoni bromodomain containing protein 0.0088 0.0205 0.0348
Loa Loa (eye worm) hypothetical protein 0.0027 0.0023 0.0039
Echinococcus granulosus PHD finger protein 14 0.0029 0.0027 0.0046
Echinococcus granulosus sodium:glucose cotransporter 0.0086 0.0199 0.0338
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0042 0.0067 0.0173
Giardia lamblia Kinesin-13 0.0027 0.0023 0.08
Schistosoma mansoni ran 0.0115 0.0286 0.0486
Schistosoma mansoni myst-related protein 0.004 0.006 0.0102
Schistosoma mansoni survival motor neuron protein 0.0102 0.0247 0.0419
Loa Loa (eye worm) hypothetical protein 0.0031 0.0034 0.0058
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0035 0.0045 0.0116
Brugia malayi Sodium:solute symporter family protein 0.0086 0.0199 0.0516
Loa Loa (eye worm) hypothetical protein 0.0147 0.038 0.0647
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0143 0.0369 0.0369

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 9.75 mM Inhibitory activity of the compound against phospholipase A2 enzyme ChEMBL. No reference
IC50 (binding) = 9.75 mM Inhibitory activity of the compound against phospholipase A2 enzyme ChEMBL. No reference
Ki (ADMET) = 10 uM Compound was tested for the inhibition of antibody-catalyzed hydrolysis. ChEMBL. 10098662

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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