Detailed information for compound 1543586

Basic information

Technical information
  • TDR Targets ID: 1543586
  • Name: 2,3-bis(4-methoxyphenyl)-1,3-thiazolidin-4-on e
  • MW: 315.387 | Formula: C17H17NO3S
  • H donors: 0 H acceptors: 1 LogP: 3.3 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)C1SCC(=O)N1c1ccc(cc1)OC
  • InChi: 1S/C17H17NO3S/c1-20-14-7-3-12(4-8-14)17-18(16(19)11-22-17)13-5-9-15(21-2)10-6-13/h3-10,17H,11H2,1-2H3
  • InChiKey: ISZRKOJOHOJKNC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2,3-bis(4-methoxyphenyl)thiazolidin-4-one
  • 2,3-bis(4-methoxyphenyl)-4-thiazolidinone
  • Oprea1_036229

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens parathyroid hormone 1 receptor Starlite/ChEMBL No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum ko:K04588 secretin receptor, putative Get druggable targets OG5_139196 All targets in OG5_139196
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi ecdysteroid receptor 0.0103 0.0179 0.115
Brugia malayi hypothetical protein 0.0049 0.0066 0.0423
Brugia malayi Patched family protein 0.0018 0.0002 0.0008
Brugia malayi G-protein coupled receptor 0.0031 0.0031 0.0192
Schistosoma mansoni smad1 5 8 and 0.0034 0.0036 0.0053
Schistosoma mansoni myst histone acetyltransferase 0.0017 0.0001 0.0001
Onchocerca volvulus Huntingtin homolog 0.0244 0.0468 0.5275
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0031 0.003
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0031 0.0031 0.003
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0091 0.0152 0.0399
Schistosoma mansoni smad1 5 8 and 0.0034 0.0036 0.0053
Mycobacterium ulcerans hypothetical protein 0.0071 0.0112 0.0255
Brugia malayi Nuclear hormone receptor-like 1 0.0055 0.0078 0.0501
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0103 0.0179 0.115
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0005
Loa Loa (eye worm) intermediate filament protein 0.0026 0.002 0.0052
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0091 0.0152 0.0221
Plasmodium falciparum importin beta, putative 0.0029 0.0027 0.0834
Trypanosoma brucei DNA polymerase kappa, putative 0.0069 0.0108 0.0441
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0038 0.0038
Trypanosoma brucei phosphoglycerate kinase 0.0167 0.0308 0.1268
Onchocerca volvulus 0.0026 0.002 0.0215
Brugia malayi orphan nuclear receptor NR2E1 0.0049 0.0066 0.0423
Entamoeba histolytica hypothetical protein 0.0081 0.0133 0.0323
Schistosoma mansoni biogenic amine (5HT) receptor 0.0031 0.0031 0.0045
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0017 0.0001 0.0001
Leishmania major sphingosine kinase A, B, putative 0.0073 0.0116 0.0467
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0103 0.0179 0.115
Leishmania major importin beta-1 subunit, putative 0.0024 0.0015 0.005
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0005
Trypanosoma cruzi heat shock protein 85, putative 0.0026 0.002 0.008
Onchocerca volvulus 0.0071 0.0112 0.1258
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0168 0.0312 0.1282
Echinococcus granulosus snurportin 1 0.0315 0.0612 0.0889
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.006 0.0089 0.1642
Loa Loa (eye worm) hypothetical protein 0.029 0.0562 0.1472
Brugia malayi PHD-finger family protein 0.0047 0.0062 0.0395
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0011 0.004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0094 0.0382
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0112 0.2068
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0094 0.0382
Brugia malayi CHD4 protein 0.0017 0.0001 0.000000000076113
Echinococcus granulosus smad 0.0034 0.0036 0.0052
Loa Loa (eye worm) hypothetical protein 0.0148 0.027 0.0707
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0295 0.0572 0.0572
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0031 0.0031 0.008
Brugia malayi nuclear receptor NHR-88 0.0103 0.0179 0.115
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0031 0.003
Loa Loa (eye worm) hypothetical protein 0.0071 0.0112 0.0294
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0043 0.0055 0.1356
Schistosoma mansoni SET domain protein 0.0024 0.0015 0.0022
Schistosoma mansoni ferritin 0.0027 0.0022 0.0032
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0024 0.0035
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0037 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0071 0.0112 0.0294
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0031 0.003
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0043 0.0055 0.0104
Brugia malayi MH1 domain containing protein 0.0019 0.0005 0.0025
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0043 0.0055 0.0104
Echinococcus granulosus G protein coupled receptor 139 0.0031 0.0031 0.0044
Leishmania major diacylglycerol kinase-like protein 0.0073 0.0116 0.0467
Schistosoma mansoni zinc finger protein 0.0041 0.0051 0.0074
Echinococcus multilocularis ceramide kinase 0.0073 0.0116 0.0116
Echinococcus multilocularis peptidase Clp (S14 family) 0.0055 0.0079 0.0079
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0043 0.0055 0.0352
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Onchocerca volvulus 0.0024 0.0015 0.0159
Brugia malayi nuclear hormone receptor 0.0103 0.0179 0.115
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0035 0.0038 0.0056
Leishmania major cathepsin L-like protease 0.0062 0.0094 0.0375
Brugia malayi hypothetical protein 0.0031 0.0031 0.0192
Echinococcus granulosus histone lysine methyltransferase setb 0.0052 0.0073 0.0105
Brugia malayi Patched related family protein 12 0.0018 0.0002 0.0008
Trypanosoma brucei heat shock protein, putative 0.0033 0.0034 0.0138
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0029 0.0025 0.0331
Schistosoma mansoni adenoreceptor 0.0031 0.0031 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0089 0.1642
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0103 0.0179 0.115
Echinococcus granulosus tm gpcr rhodopsin 0.0031 0.0031 0.0044
Entamoeba histolytica NLI interacting factor-like phosphatase domain-containing protein 0.0025 0.0017 0.0018
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0103 0.0179 0.115
Brugia malayi neuropeptide F receptor 0.0031 0.0031 0.0192
Echinococcus granulosus g-protein coupled receptor 0.0031 0.0031 0.0044
Giardia lamblia Nuclear LIM interactor-interacting factor 1 0.0025 0.0017 0.0226
Loa Loa (eye worm) patched family protein 0.0018 0.0002 0.0005
Loa Loa (eye worm) MH2 domain-containing protein 0.0501 0.0995 0.2608
Echinococcus granulosus bloom syndrome protein 0.0021 0.0009 0.0013
Echinococcus granulosus sex peptide receptor 0.0031 0.0031 0.0044
Mycobacterium ulcerans glutaminase 0.0279 0.054 0.1379
Giardia lamblia DINP protein human, muc B family 0.0097 0.0166 0.5207
Entamoeba histolytica acyl-coA synthetase, putative 0.0148 0.027 0.0682
Trypanosoma brucei phosphoglycerate kinase 0.0167 0.0308 0.1268
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0027 0.0022 0.0017
Brugia malayi Latrophilin receptor protein 2 0.0243 0.0466 0.301
Schistosoma mansoni hepatitis B virus X associated protein hbxa 0.0017 0.0001 0.0001
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0103 0.0179 0.0178
Trichomonas vaginalis ap endonuclease, putative 0.0059 0.0087 0.16
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0023 0.0414
Schistosoma mansoni phosphoglycerate kinase 0.0167 0.0308 0.0448
Onchocerca volvulus 0.0018 0.0002 0.0014
Trypanosoma brucei ISWI complex protein 0.0028 0.0023 0.0092
Toxoplasma gondii hypothetical protein 0.0193 0.0363 0.3552
Loa Loa (eye worm) 6-phosphofructokinase 0.0113 0.0198 0.0517
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0094 0.0382
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0168 0.0312 0.1282
Echinococcus granulosus muscleblind protein 0.0147 0.0268 0.0389
Loa Loa (eye worm) hypothetical protein 0.0103 0.0179 0.0467
Echinococcus multilocularis endoplasmin 0.0026 0.002 0.002
Trypanosoma brucei hypothetical protein, conserved 0.0071 0.0112 0.046
Brugia malayi GnHR receptor homolog 0.0031 0.0031 0.0192
Brugia malayi ImpB/MucB/SamB family protein 0.0142 0.0258 0.1661
Trypanosoma brucei phosphoglycerate kinase, putative 0.0061 0.0092 0.0374
Brugia malayi RE15519p 0.0031 0.0031 0.0192
Onchocerca volvulus 0.0043 0.0055 0.0614
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0043 0.0055 0.0104
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0015 0.0263
Loa Loa (eye worm) hypothetical protein 0.0103 0.0179 0.0467
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0094 0.0382
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0031 0.003
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0103 0.0179 0.0259
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0059 0.0087 0.2805
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0059 0.0087 0.0126
Loa Loa (eye worm) hypothetical protein 0.0111 0.0193 0.0506
Loa Loa (eye worm) histone methyltransferase 0.0083 0.0137 0.0358
Trypanosoma brucei heat shock protein, putative 0.0033 0.0034 0.0138
Schistosoma mansoni hypothetical protein 0.0073 0.0116 0.0169
Loa Loa (eye worm) nuclear receptor NHR-67 0.0049 0.0066 0.0173
Trichomonas vaginalis ran, putative 0.0022 0.0011 0.0179
Onchocerca volvulus 0.0086 0.0143 0.1598
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0243 0.0466 0.0676
Entamoeba histolytica hypothetical protein 0.0081 0.0133 0.0323
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0055 0.0079 0.0166
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0099 0.0404
Echinococcus multilocularis Diacylglycerol kinase theta 0.0073 0.0116 0.0116
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0027 0.0252
Loa Loa (eye worm) hypothetical protein 0.0049 0.0066 0.0173
Echinococcus granulosus lamin 0.0026 0.002 0.0029
Echinococcus granulosus histone acetyltransferase myst4 0.0017 0.0001 0.0001
Schistosoma mansoni ferritin 0.0027 0.0022 0.0032
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0049 0.0066 0.0738
Loa Loa (eye worm) hypothetical protein 0.0148 0.027 0.0707
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0148 0.027 0.067
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0001 0.0002
Loa Loa (eye worm) patched family protein 0.0018 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0769 0.1545 0.4051
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0049 0.0066 0.0066
Trichomonas vaginalis heat shock protein, putative 0.002 0.0008 0.0129
Echinococcus multilocularis muscleblind protein 1 0.0147 0.0268 0.0267
Echinococcus multilocularis serotonin receptor 0.0031 0.0031 0.003
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Echinococcus granulosus PHD finger protein 14 0.0017 0.0001 0.0001
Brugia malayi Nuclear hormone receptor E75 0.0049 0.0066 0.0423
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0043 0.0055 0.0224
Echinococcus granulosus nuclear receptor nhr 48 0.0049 0.0066 0.0096
Trypanosoma brucei phosphoglycerate kinase 0.0061 0.0092 0.0374
Schistosoma mansoni cpg binding protein 0.0282 0.0545 0.0792
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0043 0.0055 0.0144
Loa Loa (eye worm) hypothetical protein 0.0071 0.0112 0.0294
Mycobacterium tuberculosis Conserved protein 0.0071 0.0112 0.0255
Leishmania major heat shock protein 83-1 0.0033 0.0034 0.013
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0103 0.0179 0.0467
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0031 0.0031 0.0045
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0031 0.0031 0.003
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0069
Echinococcus granulosus sphingosine kinase 1 0.1874 0.3814 0.5541
Onchocerca volvulus 0.0049 0.0066 0.0738
Trichomonas vaginalis dullard protein, putative 0.0025 0.0017 0.0304
Mycobacterium ulcerans acyl-CoA synthetase 0.0043 0.0055 0.0104
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0103 0.0179 0.0467
Schistosoma mansoni cpg binding protein 0.0282 0.0545 0.0792
Trypanosoma brucei DNA polymerase eta, putative 0.0142 0.0258 0.1059
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0228 0.0434 0.0631
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0029 0.09
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0071 0.0112 0.0255
Schistosoma mansoni neuropeptide receptor 0.0031 0.0031 0.0045
Schistosoma mansoni glutaminase 0.0279 0.054 0.0784
Echinococcus multilocularis g protein coupled receptor 0.0031 0.0031 0.003
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0038 0.0038
Trypanosoma brucei hypothetical protein, conserved 0.0028 0.0024 0.0095
Echinococcus multilocularis histone acetyltransferase myst3 0.0017 0.0001 0.0001
Mycobacterium ulcerans hypothetical protein 0.063 0.1261 0.3278
Schistosoma mansoni hypothetical protein 0.012 0.0212 0.0309
Schistosoma mansoni growth hormone secretagogue receptor 0.0031 0.0031 0.0045
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0017 0.0064
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0002
Schistosoma mansoni biogenic amine receptor 0.0031 0.0031 0.0045
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0073 0.0116 0.0169
Onchocerca volvulus 0.0031 0.0031 0.0335
Mycobacterium ulcerans acetyl-CoA synthetase 0.0043 0.0055 0.0104
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0011 0.0314
Loa Loa (eye worm) nuclear hormone receptor 0.0049 0.0066 0.0173
Toxoplasma gondii histone lysine methyltransferase SET1 0.0513 0.1019 1
Trichomonas vaginalis heat shock protein, putative 0.0026 0.002 0.0361
Loa Loa (eye worm) patched family protein 0.0018 0.0002 0.0005
Loa Loa (eye worm) PHD-finger family protein 0.0017 0.0001 0.0002
Echinococcus granulosus geminin 0.0701 0.1406 0.2042
Schistosoma mansoni alpha-1 adrenergic receptor 0.0031 0.0031 0.0045
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0011 0.0063
Brugia malayi Myosin head containing protein 0.0018 0.0002 0.0008
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0228 0.0434 0.2805
Echinococcus granulosus 6 phosphofructokinase 0.0113 0.0198 0.0286
Schistosoma mansoni myosin xvIII 0.0031 0.0031 0.0045
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0027 0.0022 0.0218
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0105 0.0181 0.0435
Toxoplasma gondii diacylglycerol kinase accessory domain (presumed) domain-containing protein 0.0073 0.0116 0.113
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0031 0.0031 0.0044
Schistosoma mansoni hypothetical protein 0.0243 0.0466 0.0677
Leishmania major 4-coumarate:coa ligase-like protein 0.0148 0.027 0.1103
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Brugia malayi AMP-binding enzyme family protein 0.0043 0.0055 0.0352
Mycobacterium ulcerans beta-lactamase 0.0071 0.0112 0.0255
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0005
Schistosoma mansoni neuropeptide f receptor 76f 0.0031 0.0031 0.0045
Loa Loa (eye worm) TYRA-2 protein 0.0031 0.0031 0.008
Echinococcus multilocularis Niemann Pick C1 protein 0.0415 0.0817 0.0817
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Leishmania major acetyl-CoA synthetase, putative 0.0043 0.0055 0.0216
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0065 0.01 0.01
Schistosoma mansoni neuropeptide F-like receptor 0.0031 0.0031 0.0045
Plasmodium vivax SNF2 family N-terminal domain containing protein 0.0017 0.0001 0.00000000038261
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0094 0.0382
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0028 0.0024 0.0225
Loa Loa (eye worm) endoplasmin 0.0033 0.0034 0.0089
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0088 0.0148 0.2724
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0089 0.1642
Loa Loa (eye worm) hypothetical protein 0.0043 0.0055 0.0144
Onchocerca volvulus 0.0031 0.0031 0.0335
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0005
Leishmania major heat shock protein 83-1 0.0033 0.0034 0.013
Trypanosoma brucei DNA polymerase kappa, putative 0.0069 0.0108 0.0441
Schistosoma mansoni jumonji/arid domain-containing protein 0.0017 0.0001 0.0001
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0059 0.0087 0.0201
Trichomonas vaginalis ap endonuclease, putative 0.0059 0.0087 0.16
Echinococcus granulosus tm gpcr rhodopsin 0.0031 0.0031 0.0044
Trypanosoma cruzi DNA polymerase eta, putative 0.0142 0.0258 0.1059
Echinococcus granulosus beta LACTamase domain containing family member 0.0071 0.0112 0.0163
Loa Loa (eye worm) hypothetical protein 0.0049 0.0066 0.0173
Leishmania major cathepsin L-like protease 0.0062 0.0094 0.0375
Echinococcus granulosus tachykinin peptides receptor 99D 0.0031 0.0031 0.0044
Loa Loa (eye worm) hypothetical protein 0.0103 0.0179 0.0467
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0017 0.0064
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0059 0.0087 0.0356
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0103 0.0179 0.0259
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0084 0.0138 0.1348
Echinococcus granulosus histone acetyltransferase KAT2B 0.0285 0.0551 0.0799
Brugia malayi nuclear hormone receptor family member odr-7 0.0049 0.0066 0.0423
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0094 0.0382
Echinococcus granulosus lamin dm0 0.0026 0.002 0.0029
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0043 0.0055 0.0104
Onchocerca volvulus 0.0035 0.0038 0.0421
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0043 0.0055 0.177
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0167 0.0308 1
Trypanosoma cruzi diacylglycerol kinase, putative 0.0073 0.0116 0.0475
Trypanosoma cruzi Sphingosine kinase 0.0073 0.0116 0.0475
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0055 0.0078 0.0113
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0031 0.0044
Echinococcus granulosus endoplasmin 0.0026 0.002 0.0029
Mycobacterium ulcerans bacterioferritin BfrA 0.0027 0.0022 0.0017
Brugia malayi MH2 domain containing protein 0.0034 0.0036 0.0228
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0049 0.0066 0.0096
Leishmania major hypothetical protein, conserved 0.0073 0.0116 0.0467
Loa Loa (eye worm) F/Y-rich family protein 0.0017 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0055 0.0078 0.0205
Echinococcus multilocularis microtubule associated protein 2 0.2867 0.5853 0.5853
Plasmodium vivax phosphoglycerate kinase, putative 0.0167 0.0308 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0042
Schistosoma mansoni apoferritin-2 0.0027 0.0022 0.0032
Brugia malayi Patched family protein 0.0018 0.0002 0.0008
Leishmania major 4-coumarate:coa ligase-like protein 0.0148 0.027 0.1103
Brugia malayi Patched family protein 0.0018 0.0002 0.0008
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0031 0.0031 0.0044
Echinococcus granulosus dna polymerase eta 0.0142 0.0258 0.0374
Onchocerca volvulus 0.0048 0.0064 0.071
Loa Loa (eye worm) hypothetical protein 0.0055 0.0078 0.0205
Brugia malayi Patched family protein 0.0018 0.0002 0.0008
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0067 0.0104 0.0103
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0005
Schistosoma mansoni terminal deoxycytidyl transferase 0.0091 0.0152 0.0221
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0031 0.0031 0.0044
Schistosoma mansoni hypothetical protein 0.0243 0.0466 0.0677
Schistosoma mansoni apoferritin-2 0.0027 0.0022 0.0032
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0035 0.0037 0.0355
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0103 0.0179 0.0467
Brugia malayi hypothetical protein 0.0018 0.0002 0.0008
Trypanosoma cruzi Heat shock protein 83, putative 0.0033 0.0034 0.0138
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.002 0.0123
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0031 0.0044
Loa Loa (eye worm) hypothetical protein 0.0054 0.0077 0.0202
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0029 0.0272
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.006 0.0089 0.1642
Toxoplasma gondii diacylglycerol kinase catalytic domain-containing protein 0.0073 0.0116 0.113
Leishmania major heat shock protein 83-1 0.0033 0.0034 0.013
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0055 0.0078 0.0114
Echinococcus multilocularis phosphoglycerate kinase 1 0.0167 0.0308 0.0308
Loa Loa (eye worm) Smad1 0.0034 0.0036 0.0094
Loa Loa (eye worm) diacylglycerol kinase 2 0.0073 0.0116 0.0303
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0103 0.0179 0.0178
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0043 0.0055 0.0224
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0049 0.0066 0.0096
Leishmania major heat shock protein 83-1 0.0033 0.0034 0.013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0094 0.0382
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0043 0.0055 0.0104
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0025 0.0017 0.0534
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Leishmania major DNA polymerase eta, putative 0.0142 0.0258 0.1052
Echinococcus granulosus 7TM GPCR rhodopsin 0.0031 0.0031 0.0044
Brugia malayi CHE-14 protein 0.0124 0.0222 0.1429
Echinococcus granulosus Protein patched homolog 1 0.0124 0.0222 0.0322
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0094 0.0382
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0094 0.0382
Brugia malayi Patched family protein 0.0018 0.0002 0.0008
Echinococcus granulosus CTD small phosphatase protein like 0.0025 0.0017 0.0025
Echinococcus granulosus dnaJ subfamily B 0.3369 0.6883 1
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0031 0.0031 0.003
Trypanosoma brucei hypothetical protein, conserved 0.0028 0.0024 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0089 0.1642
Mycobacterium ulcerans acyl-CoA synthetase 0.0148 0.027 0.067
Loa Loa (eye worm) hypothetical protein 0.0167 0.0308 0.0807
Loa Loa (eye worm) beta-lactamase 0.0071 0.0112 0.0294
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0043 0.0055 0.0104
Echinococcus granulosus FTZ F1 alpha 0.0103 0.0179 0.0259
Schistosoma mansoni coup transcription factor 0.0103 0.0179 0.0259
Schistosoma mansoni 6-phosphofructokinase 0.0113 0.0198 0.0287
Trypanosoma cruzi Sphingosine kinase 0.0073 0.0116 0.0475
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.0016 0.0053
Echinococcus granulosus lysine specific demethylase 5B 0.0017 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0026 0.002 0.0052
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0031 0.0045
Onchocerca volvulus Neuropeptide F receptor homolog 0.0031 0.0031 0.0335
Schistosoma mansoni retinoic acid receptor RXR 0.0103 0.0179 0.0259
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0198 0.3649
Onchocerca volvulus 0.0018 0.0002 0.0014
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0031 0.0031 0.0045
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0024 0.0095
Onchocerca volvulus Protein patched homolog 0.0018 0.0002 0.0014
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0167 0.0308 0.3018
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0065 0.0099 0.0098
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0243 0.0466 0.301
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0043 0.0055 0.0224
Brugia malayi Probable ClpP-like protease 0.0084 0.0138 0.0889
Loa Loa (eye worm) G-protein coupled receptor 0.0031 0.0031 0.008
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0061 0.0092 0.0374
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0065 0.0099 0.0232
Mycobacterium ulcerans DNA polymerase IV 0.0117 0.0206 0.05
Echinococcus granulosus neuropeptide s receptor 0.0979 0.1975 0.287
Brugia malayi ORL1-like opioid receptor 0.0031 0.0031 0.0192
Echinococcus multilocularis G protein coupled receptor 139 0.0031 0.0031 0.003
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0205 0.0387 0.1594
Leishmania major 4-coumarate:coa ligase-like protein 0.0148 0.027 0.1103
Loa Loa (eye worm) hypothetical protein 0.0049 0.0066 0.0173
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0005
Schistosoma mansoni endoplasmin 0.0033 0.0034 0.005
Loa Loa (eye worm) PHD-finger family protein 0.0017 0.0001 0.0002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.006 0.0089 0.1642
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0029 0.0442
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0038 0.0055
Loa Loa (eye worm) hypothetical protein 0.0064 0.0098 0.0255
Echinococcus granulosus expressed protein 0.0027 0.0022 0.0032
Schistosoma mansoni amine GPCR 0.0031 0.0031 0.0045
Mycobacterium ulcerans acyl-CoA synthetase 0.0043 0.0055 0.0104
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0112 0.2068
Onchocerca volvulus 0.0031 0.0031 0.0335
Loa Loa (eye worm) hypothetical protein 0.0049 0.0066 0.0173
Trichomonas vaginalis dullard protein, putative 0.0025 0.0017 0.0304
Mycobacterium ulcerans DNA polymerase IV 0.0117 0.0206 0.05
Onchocerca volvulus Huntingtin homolog 0.0244 0.0468 0.5275
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0031 0.0031 0.003
Schistosoma mansoni cellular tumor antigen P53 0.0098 0.0168 0.0243
Leishmania major diacylglycerol kinase, putative 0.0073 0.0116 0.0467
Schistosoma mansoni neuropeptide receptor 0.0031 0.0031 0.0045
Brugia malayi protein C24B5.3 0.0018 0.0002 0.0008
Trypanosoma brucei heat shock protein, putative 0.0033 0.0034 0.0138
Schistosoma mansoni hypothetical protein 0.012 0.0212 0.0309
Brugia malayi AMP-binding enzyme family protein 0.0043 0.0055 0.0352
Trypanosoma brucei heat shock protein, putative 0.0033 0.0034 0.0138
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0031 0.0031 0.0044
Toxoplasma gondii isocitrate dehydrogenase 0.0065 0.01 0.0976
Loa Loa (eye worm) hypothetical protein 0.0147 0.0268 0.0701
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0002
Onchocerca volvulus 0.0103 0.0179 0.2005
Echinococcus granulosus mothers against decapentaplegic 5 0.0034 0.0036 0.0052
Trypanosoma cruzi DNA polymerase kappa, putative 0.0117 0.0206 0.0845
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0031 0.0031 0.0045
Schistosoma mansoni neuropeptide receptor 0.0031 0.0031 0.0045
Brugia malayi nuclear hormone receptor family member nhr-6 0.0049 0.0066 0.0423
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0566 0.1129 0.4657
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0061 0.0092 0.0374
Brugia malayi MH2 domain containing protein 0.0034 0.0036 0.0228
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0065 0.01 0.3235
Trypanosoma cruzi Diacylglycerol kinase catalytic domain containing protein, putative 0.0073 0.0116 0.0475
Trichomonas vaginalis bromodomain-containing protein, putative 0.0088 0.0148 0.2724
Brugia malayi Pre-SET motif family protein 0.021 0.0398 0.2573
Brugia malayi hypothetical protein 0.0055 0.0078 0.0501
Brugia malayi F/Y-rich N-terminus family protein 0.0084 0.0138 0.089
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0077 0.0315
Schistosoma mansoni hypothetical protein 0.002 0.0008 0.0011
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0027 0.0026
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0198 0.0491
Echinococcus granulosus orexin receptor type 2 0.0031 0.0031 0.0044
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0061 0.0092 0.0374
Echinococcus granulosus Smad4 0.0034 0.0036 0.0052
Loa Loa (eye worm) hypothetical protein 0.0111 0.0193 0.0506
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0025 0.0017 0.0534
Brugia malayi Dopamine receptor protein 2 0.0031 0.0031 0.0192
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0067 0.0104 0.0103
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0005
Trypanosoma cruzi heat shock protein 85, putative 0.0033 0.0034 0.0138
Brugia malayi AMP-binding enzyme family protein 0.0148 0.027 0.1743
Toxoplasma gondii propionate-CoA ligase 0.0043 0.0055 0.0534
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.006 0.0089 0.1642
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0103 0.0179 0.0259
Trypanosoma brucei DNA polymerase kappa, putative 0.0117 0.0206 0.0845
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0065 0.0099 0.0633
Echinococcus granulosus ceramide kinase 0.0073 0.0116 0.0168
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0089 0.1642
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0009 0.0052
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0043 0.0055 0.0104
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0071 0.0112 0.0255
Echinococcus multilocularis thyroid hormone receptor alpha 0.0103 0.0179 0.0178
Brugia malayi G-protein coupled receptor 0.0031 0.0031 0.0192
Brugia malayi hypothetical protein 0.0055 0.0078 0.0501
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0029 0.09
Leishmania major GTP-binding protein, putative 0.0022 0.0011 0.0032
Echinococcus granulosus g protein coupled receptor 0.0031 0.0031 0.0044
Entamoeba histolytica hypothetical protein 0.0024 0.0016 0.0013
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0079 0.0129 0.1259
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0089 0.1642
Schistosoma mansoni biogenic amine receptor 0.0031 0.0031 0.0045
Trypanosoma brucei hypothetical protein, conserved 0.0073 0.0116 0.0475
Plasmodium falciparum phosphoglycerate kinase 0.0167 0.0308 1
Echinococcus granulosus Diacylglycerol kinase theta 0.0073 0.0116 0.0168
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Mycobacterium tuberculosis Conserved protein 0.1874 0.3814 1
Trypanosoma brucei heat shock protein 90, putative 0.0033 0.0034 0.0138
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0049 0.0066 0.0096
Loa Loa (eye worm) RecQ helicase 0.0021 0.0009 0.0023
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0015 0.0263
Entamoeba histolytica phosphoglycerate kinase, putative 0.0167 0.0308 0.0782
Loa Loa (eye worm) hypothetical protein 0.0071 0.0112 0.0294
Onchocerca volvulus 0.0043 0.0055 0.0614
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0016 0.0061
Loa Loa (eye worm) hypothetical protein 0.0111 0.0193 0.0506
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0055 0.0078 0.0114
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0031 0.0031 0.0192
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0086 0.0143 0.0207
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0043 0.0055 0.0534
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0052 0.0073 0.0072
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0031 0.0031 0.0192
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.006 0.0089 0.1642
Schistosoma mansoni Smad4 0.0034 0.0036 0.0053
Echinococcus multilocularis g protein coupled receptor 0.0031 0.0031 0.003
Echinococcus granulosus mixed lineage leukemia protein mll 0.0067 0.0104 0.015
Loa Loa (eye worm) hypothetical protein 0.0026 0.0019 0.0049
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0031 0.0031 0.0044
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0031 0.0031 0.008
Trypanosoma brucei DNA damage repair protein, putative 0.0028 0.0024 0.0095
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0031 0.0031 0.0045
Mycobacterium ulcerans hypothetical protein 0.0148 0.027 0.067
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0015 0.0263
Schistosoma mansoni amine GPCR 0.0031 0.0031 0.0045
Brugia malayi Diacylglycerol kinase protein 2 0.0073 0.0116 0.0745
Echinococcus multilocularis geminin 0.0701 0.1406 0.1406
Brugia malayi protein C24B5.3 0.0018 0.0002 0.0008
Leishmania major DNA damage repair protein, putative 0.0028 0.0024 0.0087
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0043 0.0055 0.0104
Brugia malayi hypothetical protein 0.0233 0.0445 0.2877
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0073 0.0116 0.0475
Loa Loa (eye worm) hypothetical protein 0.0084 0.0138 0.0362
Echinococcus granulosus acylglycerol kinase mitochondrial 0.0073 0.0116 0.0168
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0455 0.0901 0.233
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0043 0.0055 0.0144
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0025 0.0017 0.0304
Brugia malayi MH2 domain containing protein 0.0501 0.0995 0.6437
Echinococcus granulosus ecdysone induced protein 78C 0.0103 0.0179 0.0259
Loa Loa (eye worm) hypothetical protein 0.0049 0.0066 0.0173
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0017 0.0505
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0094 0.0382
Schistosoma mansoni phd finger protein 0.0017 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0295 0.0572 0.0831
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0031 0.0031 0.0045
Loa Loa (eye worm) hypothetical protein 0.0244 0.0468 0.1226
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0148 0.027 0.8698
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0071 0.0112 0.0255
Mycobacterium ulcerans acyl-CoA synthetase 0.0043 0.0055 0.0104
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0089 0.1642
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Trypanosoma brucei unspecified product 0.0063 0.0095 0.0386
Trichomonas vaginalis antibiotic synthetase, putative 0.0043 0.0055 0.101
Loa Loa (eye worm) CHromoDomain protein family member 0.0017 0.0001 0.0002
Echinococcus granulosus TGF beta signal transducer SmadC 0.0034 0.0036 0.0052
Plasmodium falciparum endoplasmin, putative 0.002 0.0008 0.0227
Brugia malayi hypothetical protein 0.0031 0.0031 0.0192
Toxoplasma gondii hypothetical protein 0.0029 0.0025 0.024
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0059 0.0087 0.2572
Echinococcus granulosus transcription factor Dp 1 0.0037 0.0043 0.0062
Trypanosoma brucei chrX additional, unordered contigs 0.0028 0.0024 0.0095
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Brugia malayi nuclear receptor RXR 0.0055 0.0078 0.0501
Mycobacterium tuberculosis Probable lipase LipE 0.0071 0.0112 0.0255
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.006 0.0089 0.1642
Leishmania major heat shock protein 83-1 0.0033 0.0034 0.013
Brugia malayi putative neuropeptide receptor 0.0031 0.0031 0.0192
Brugia malayi Phosphoglycerate kinase 0.0061 0.0092 0.0587
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0002
Onchocerca volvulus 0.0071 0.0112 0.1258
Onchocerca volvulus 0.0098 0.0168 0.188
Echinococcus multilocularis ferritin 0.0027 0.0022 0.0022
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0031 0.003
Mycobacterium tuberculosis Probable esterase LipL 0.0071 0.0112 0.0255
Echinococcus granulosus tumor protein p63 0.067 0.1342 0.1949
Leishmania major hypothetical protein, conserved 0.0025 0.0017 0.0056
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0005
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0084 0.0138 0.4189
Entamoeba histolytica hypothetical protein, conserved 0.1874 0.3814 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0066 0.027
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0026 0.002 0.0029
Echinococcus multilocularis survival motor neuron protein 1 0.0233 0.0445 0.0445
Plasmodium vivax importin-beta 2, putative 0.0029 0.0027 0.0834
Schistosoma mansoni diacylglycerol kinase theta 0.0073 0.0116 0.0169
Leishmania major DNA polymerase kappa, putative 0.0028 0.0024 0.0087
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0005
Echinococcus granulosus peptidase Clp S14 family 0.0055 0.0079 0.0114
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0228 0.0434 0.0631
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0113 0.0198 0.6218
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0031 0.0044
Schistosoma mansoni phd finger protein 0.0017 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0097 0.0166 0.0679
Echinococcus multilocularis heat shock protein 0.0033 0.0034 0.0034
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0113 0.0198 0.0479
Brugia malayi Bromodomain containing protein 0.0045 0.0058 0.0368
Leishmania major heat shock protein 83-1 0.0033 0.0034 0.013
Echinococcus multilocularis phd finger protein 12 0.0017 0.0001 0.0001
Trypanosoma brucei heat shock protein, putative 0.0033 0.0034 0.0138
Loa Loa (eye worm) hypothetical protein 0.0055 0.0078 0.0205
Toxoplasma gondii patched family protein 0.0018 0.0002 0.0012
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0043 0.0055 0.0104
Echinococcus granulosus uro adherence factor A 0.0017 0.0001 0.0001
Loa Loa (eye worm) neuropeptide F receptor 0.0031 0.0031 0.008
Schistosoma mansoni hypothetical protein 0.0243 0.0466 0.0677
Toxoplasma gondii hypothetical protein 0.0018 0.0002 0.0012
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0084 0.0138 0.0138
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0029 0.0047
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0037 0.0042 0.0062
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0052 0.0073 0.0105
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0005
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0073 0.0116 0.2135
Leishmania major heat shock protein 83-1 0.0033 0.0034 0.013
Trichomonas vaginalis conserved hypothetical protein 0.0124 0.0222 0.4097
Brugia malayi Patched family protein 0.0018 0.0002 0.0008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0002
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0071 0.0112 0.0721
Schistosoma mansoni nuclear receptor nhr-48 0.0049 0.0066 0.0096
Plasmodium vivax endoplasmin, putative 0.0033 0.0034 0.1085
Onchocerca volvulus 0.0031 0.0031 0.0335
Trypanosoma cruzi heat shock protein 90, putative 0.002 0.0006 0.0022
Schistosoma mansoni heat shock protein 0.0033 0.0034 0.005
Trypanosoma cruzi heat shock protein 90, putative 0.0026 0.002 0.008
Trypanosoma brucei mitochondrial DNA polymerase beta 0.1197 0.2424 1
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0198 0.3649
Loa Loa (eye worm) hypothetical protein 0.0147 0.0268 0.0701
Schistosoma mansoni ferritin light chain 0.0027 0.0022 0.0032
Trichomonas vaginalis hypothetical protein 0.0032 0.0032 0.0581
Trichomonas vaginalis diacylglycerol kinase, epsilon, putative 0.0073 0.0116 0.2135
Loa Loa (eye worm) melatonin receptor type 1A 0.0031 0.0031 0.008
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0563 0.1123 0.1631
Schistosoma mansoni bromodomain containing protein 0.0084 0.0139 0.0202
Trichomonas vaginalis antibiotic synthetase, putative 0.0043 0.0055 0.101
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0005
Echinococcus granulosus GPCR family 2 0.0243 0.0466 0.0676
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0167 0.0308 0.1268
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0113 0.0198 0.0811
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0018 0.0003 0.0008
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0065 0.01 0.3235
Brugia malayi 6-phosphofructokinase 0.0113 0.0198 0.1273
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0023 0.0414
Onchocerca volvulus 0.0031 0.0031 0.0335
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0113 0.0198 0.6218
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0043 0.0055 0.0352
Brugia malayi neuropeptide F receptor 0.0031 0.0031 0.0192
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0031 0.0045
Onchocerca volvulus Ceramide kinase 1 homolog 0.0073 0.0116 0.1299
Echinococcus multilocularis 6 phosphofructokinase 0.0113 0.0198 0.0197
Entamoeba histolytica acyl-CoA synthetase, putative 0.0148 0.027 0.0682
Echinococcus multilocularis mothers against decapentaplegic 5 0.0034 0.0036 0.0036
Schistosoma mansoni heat shock protein 0.0033 0.0034 0.005
Brugia malayi Tachykinin-like peptides receptor 99D 0.0031 0.0031 0.0192
Mycobacterium leprae Probable lipase LipE 0.0071 0.0112 0.3306
Loa Loa (eye worm) hypothetical protein 0.0055 0.0078 0.0205
Echinococcus granulosus cpg binding protein 0.0282 0.0545 0.0792
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0005
Leishmania major heat shock protein 83-1 0.0033 0.0034 0.013
Schistosoma mansoni nuclear hormone receptor 0.0103 0.0179 0.0259
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0029 0.0513
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0043 0.0055 0.0104
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0025 0.0017 0.0304
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0084 0.0138 0.4189
Echinococcus multilocularis lamin dm0 0.0026 0.002 0.002
Echinococcus granulosus zinc finger protein 0.0041 0.0051 0.0074
Leishmania major heat shock protein 83-1 0.0033 0.0034 0.013
Schistosoma mansoni bromodomain containing protein 0.0026 0.002 0.003
Onchocerca volvulus 0.0031 0.0031 0.0335
Onchocerca volvulus 0.0239 0.0456 0.5143
Echinococcus multilocularis cpg binding protein 0.0282 0.0545 0.0545
Trichomonas vaginalis esterase, putative 0.0071 0.0112 0.2068
Trichomonas vaginalis helicase, putative 0.006 0.0089 0.1642
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0228 0.0434 0.0434
Mycobacterium ulcerans acyl-CoA synthetase 0.0043 0.0055 0.0104
Echinococcus multilocularis lysine specific demethylase 5B 0.0017 0.0001 0.0001
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0103 0.0179 0.115
Loa Loa (eye worm) hypothetical protein 0.0073 0.0116 0.0303
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Brugia malayi Importin beta-1 subunit 0.0029 0.0027 0.0166
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0103 0.0179 0.115
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0103 0.0179 0.0259
Schistosoma mansoni biogenic amine (5HT) receptor 0.0031 0.0031 0.0045
Loa Loa (eye worm) hypothetical protein 0.0071 0.0112 0.0294
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0043 0.0055 0.0216
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0228 0.0434 0.063
Loa Loa (eye worm) hypothetical protein 0.0103 0.0179 0.0467
Trypanosoma brucei DNA polymerase kappa, putative 0.0054 0.0077 0.0315
Schistosoma mansoni phosphoglycerate kinase 0.0167 0.0308 0.0448
Giardia lamblia Histone acetyltransferase GCN5 0.0079 0.0128 0.3952
Mycobacterium tuberculosis Conserved protein 0.0071 0.0112 0.0255
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.1197 0.2424 1
Chlamydia trachomatis phosphoglycerate kinase 0.0167 0.0308 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0002
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0031 0.0031 0.0045
Toxoplasma gondii heat shock protein 90, putative 0.0033 0.0034 0.0327
Trypanosoma brucei DNA polymerase kappa, putative 0.0117 0.0206 0.0845
Echinococcus multilocularis neuropeptide s receptor 0.0979 0.1975 0.1975
Trichomonas vaginalis glutaminase, putative 0.0279 0.054 1
Loa Loa (eye worm) hypothetical protein 0.0526 0.1046 0.2741
Brugia malayi MH1 domain containing protein 0.0019 0.0005 0.0025
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0103 0.0179 0.0467
Trypanosoma cruzi DNA polymerase kappa, putative 0.0117 0.0206 0.0845
Brugia malayi beta-lactamase family protein 0.0071 0.0112 0.0721
Brugia malayi exodeoxyribonuclease III family protein 0.0059 0.0087 0.0558
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0045
Brugia malayi AMP-binding enzyme family protein 0.0043 0.0055 0.0352
Schistosoma mansoni diacylglycerol kinase zeta iota 0.0073 0.0116 0.0169
Echinococcus granulosus PHD and RING finger domain containing protein 1 0.0017 0.0001 0.0001
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0031 0.0031 0.003
Brugia malayi hypothetical protein 0.0031 0.0031 0.0192
Echinococcus multilocularis neuropeptide receptor 0.0031 0.0031 0.003
Schistosoma mansoni thyroid hormone receptor 0.0103 0.0179 0.0259
Entamoeba histolytica hypothetical protein 0.0081 0.0133 0.0323
Plasmodium falciparum NLI interacting factor-like phosphatase, putative 0.0025 0.0017 0.0534
Trichomonas vaginalis DNA polymerase eta, putative 0.0117 0.0206 0.3801
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0043 0.0055 0.008
Echinococcus granulosus neuropeptide Y receptor 0.0031 0.0031 0.0044
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0029 0.0513
Trichomonas vaginalis diacylglycerol kinase, putative 0.0073 0.0116 0.2135
Loa Loa (eye worm) hypothetical protein 0.0148 0.027 0.0707
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0099 0.0404
Echinococcus multilocularis somatostatin receptor 0.0031 0.0031 0.003
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0103 0.0179 0.0259
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0081 0.0132 0.0131
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0025 0.0017 0.0025
Onchocerca volvulus 0.0051 0.0071 0.0795
Onchocerca volvulus 0.0448 0.0887 1
Echinococcus granulosus neuropeptide Y receptor 0.0031 0.0031 0.0044
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0111 0.0193 0.0467
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0103 0.0179 0.0178
Leishmania major hypothetical protein, conserved 0.0073 0.0116 0.0467
Schistosoma mansoni nuclear hormone receptor 0.0049 0.0066 0.0096
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0112 0.046
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0005
Trypanosoma cruzi heat shock protein 85, putative 0.0033 0.0034 0.0138
Echinococcus granulosus heat shock protein 90 0.0033 0.0034 0.0049
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0016 0.048
Brugia malayi Patched related family protein 4 0.0018 0.0002 0.0008
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.029 0.0562 0.1449
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0034 0.0036 0.0053
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0017 0.0505
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0031 0.0031 0.0045
Brugia malayi hypothetical protein 0.0049 0.0066 0.0423
Echinococcus granulosus Niemann Pick C1 protein 0.0415 0.0817 0.1187
Brugia malayi Phosphoglycerate kinase 0.0167 0.0308 0.1989
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0031 0.0045
Brugia malayi hypothetical protein 0.0448 0.0887 0.5734
Trichomonas vaginalis heat shock protein, putative 0.0026 0.002 0.0361
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0103 0.0179 0.0178
Echinococcus multilocularis zinc finger protein 0.0041 0.0051 0.0051
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0065 0.01 0.01
Brugia malayi hypothetical protein 0.0031 0.0031 0.0192
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0103 0.0179 0.0467
Plasmodium falciparum histone acetyltransferase GCN5 0.0079 0.0128 0.4142
Brugia malayi G protein-coupled receptor 0.0031 0.0031 0.0192
Brugia malayi beta-lactamase family protein 0.0071 0.0112 0.0721
Mycobacterium tuberculosis Probable hydrolase 0.0071 0.0112 0.0255
Schistosoma mansoni ap endonuclease 0.0059 0.0087 0.0127
Loa Loa (eye worm) hypothetical protein 0.0243 0.0466 0.122
Leishmania major DNA polymerase kappa, putative 0.0097 0.0166 0.0672
Echinococcus multilocularis acylglycerol kinase, mitochondrial 0.0073 0.0116 0.0116
Echinococcus granulosus peptide allatostatin:somatostatin 0.0031 0.0031 0.0044
Echinococcus granulosus 7tm_1 domain containing protein 0.0031 0.0031 0.0044
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0031 0.0031 0.0045
Echinococcus granulosus somatostatin receptor 0.0031 0.0031 0.0044
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0024 0.0016 0.0145
Loa Loa (eye worm) hypothetical protein 0.0111 0.0193 0.0506
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0073 0.0116 0.2135
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0043 0.0055 0.0104
Mycobacterium ulcerans hypothetical protein 0.1874 0.3814 1
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0112 0.2068
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0034 0.0036 0.0036
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0031 0.003
Echinococcus granulosus L aminoadipate semialdehyde 0.0086 0.0143 0.0206
Echinococcus granulosus dna polymerase kappa 0.0117 0.0206 0.0298
Brugia malayi ImpB/MucB/SamB family protein 0.0091 0.0152 0.098
Loa Loa (eye worm) hypothetical protein 0.0049 0.0066 0.0173
Schistosoma mansoni ran 0.0022 0.0011 0.0015
Loa Loa (eye worm) hypothetical protein 0.0103 0.0179 0.0467
Trichomonas vaginalis dullard protein, putative 0.0025 0.0017 0.0304
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0084 0.0138 0.4189
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0071 0.0112 0.0294
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0032 0.0581
Schistosoma mansoni nuclear hormone receptor 0.0049 0.0066 0.0096
Echinococcus multilocularis isocitrate dehydrogenase 0.0065 0.01 0.01
Echinococcus multilocularis remodeling and spacing factor 1 0.0017 0.0001 0.0001
Brugia malayi hypothetical protein 0.0031 0.0031 0.0192
Entamoeba histolytica heat shock protein 90, putative 0.0033 0.0034 0.0062
Treponema pallidum exodeoxyribonuclease (exoA) 0.0059 0.0087 0.2442
Brugia malayi Patched family protein 0.0018 0.0002 0.0008
Brugia malayi G protein-coupled receptor F59B2.13 0.0031 0.0031 0.0192
Echinococcus multilocularis sterol regulatory element binding protein 0.0124 0.0222 0.0221
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0065 0.0099 0.0144
Treponema pallidum phosphoglycerate kinase 0.0167 0.0308 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0031 0.003
Schistosoma mansoni nuclear receptor 0.0049 0.0066 0.0096
Echinococcus multilocularis fmrfamide receptor 0.0031 0.0031 0.003
Echinococcus multilocularis dna polymerase kappa 0.0117 0.0206 0.0205
Brugia malayi hypothetical protein 0.0244 0.0468 0.3025
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0018 0.0004 0.0091
Onchocerca volvulus 0.0018 0.0002 0.0014
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0167 0.0308 0.5703
Echinococcus granulosus tm gpcr rhodopsin 0.0031 0.0031 0.0044
Echinococcus granulosus neuropeptide receptor A26 0.0979 0.1975 0.287
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0002
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0065 0.01 0.01
Schistosoma mansoni patched 1 0.0124 0.0222 0.0322
Loa Loa (eye worm) patched family protein 0.0018 0.0002 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0117 0.0206 0.0845
Onchocerca volvulus 0.0031 0.0031 0.0335
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0061 0.0092 0.0366
Echinococcus multilocularis snurportin 1 0.0315 0.0612 0.0612
Leishmania major phosphoglycerate kinase C, glycosomal 0.0167 0.0308 0.1261
Entamoeba histolytica diacylglycerol kinase, putative 0.0073 0.0116 0.0277
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0059 0.0087 0.2442
Schistosoma mansoni ran 0.0022 0.0011 0.0015
Mycobacterium ulcerans heat shock protein 90 0.0026 0.002 0.0012
Onchocerca volvulus 0.0049 0.0066 0.0738
Loa Loa (eye worm) hypothetical protein 0.0049 0.0066 0.0173
Trypanosoma brucei Mitochondrial import inner membrane translocase subunit TIM50 0.0025 0.0017 0.0068
Echinococcus granulosus TAF3 RNA polymerase II TATA box binding protein 0.0017 0.0001 0.0001
Schistosoma mansoni opsin-like receptor 0.0031 0.0031 0.0045
Echinococcus multilocularis uro adherence factor A 0.0017 0.0001 0.0001
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0167 0.0308 0.5703
Schistosoma mansoni hypothetical protein 0.0315 0.0612 0.0889
Toxoplasma gondii ABC1 family protein 0.0071 0.0112 0.1094
Brugia malayi Nuclear hormone receptor-like 1 0.0055 0.0078 0.0501
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0769 0.1545 0.4051
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0566 0.1129 0.4657
Echinococcus granulosus Zinc finger DBF type 0.0017 0.0001 0.0001
Mycobacterium ulcerans diacylglycerol kinase 0.0073 0.0116 0.0264
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0091 0.0152 0.0221
Echinococcus multilocularis dnaJ subfamily B 0.3369 0.6883 0.6883
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0038 0.0056
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0061 0.0092 0.0374
Entamoeba histolytica hypothetical protein 0.0033 0.0034 0.0062
Treponema pallidum heat shock protein 90 0.0026 0.002 0.0161
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0084 0.0138 0.4468
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0029 0.09
Brugia malayi acetyltransferase, GNAT family protein 0.0295 0.0572 0.3699
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Loa Loa (eye worm) phosphofructokinase 0.0113 0.0198 0.0517
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0005
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0026 0.002 0.0161
Schistosoma mansoni jumonji/arid domain-containing protein 0.0017 0.0001 0.0001
Brugia malayi larval opioid receptor 0.0031 0.0031 0.0192
Loa Loa (eye worm) hypothetical protein 0.0448 0.0887 0.2324
Onchocerca volvulus 0.0043 0.0055 0.0614
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0031 0.0044
Loa Loa (eye worm) 6-phosphofructokinase 0.0113 0.0198 0.0517
Echinococcus granulosus alpha 1A adrenergic receptor 0.0031 0.0031 0.0044
Echinococcus granulosus remodeling and spacing factor 1 0.0017 0.0001 0.0001
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0015 0.0059
Brugia malayi hypothetical protein 0.0073 0.0116 0.0745
Onchocerca volvulus 0.0026 0.002 0.0215
Echinococcus granulosus sterol regulatory element binding protein 0.0124 0.0222 0.0322
Loa Loa (eye worm) CXXC zinc finger family protein 0.0265 0.051 0.1337
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0043 0.0055 0.1356
Plasmodium vivax acetyl-CoA synthetase, putative 0.0043 0.0055 0.177
Schistosoma mansoni myst-related protein 0.0033 0.0034 0.005
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0065 0.0099 0.0143
Brugia malayi AMP-binding enzyme family protein 0.0148 0.027 0.1743
Echinococcus granulosus phosphoglycerate kinase 1 0.0167 0.0308 0.0447
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0017 0.0001 0.0001
Echinococcus multilocularis serotonin receptor 0.0031 0.0031 0.003
Loa Loa (eye worm) hypothetical protein 0.0098 0.0168 0.0438
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0049 0.0066 0.0738
Echinococcus multilocularis expressed protein 0.0027 0.0022 0.0022
Echinococcus multilocularis neuropeptides capa receptor 0.0031 0.0031 0.003
Echinococcus multilocularis expressed conserved protein 0.0272 0.0526 0.0525
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0117 0.0206 0.3801
Echinococcus granulosus g protein coupled receptor 0.0031 0.0031 0.0044
Loa Loa (eye worm) hypothetical protein 0.0047 0.0063 0.0164
Schistosoma mansoni zinc finger protein 0.0017 0.0001 0.0001
Brugia malayi diacylglycerol kinase 0.0073 0.0116 0.0745
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0005
Brugia malayi nuclear receptor RXR 0.0049 0.0066 0.0423
Brugia malayi Calcitonin receptor-like protein seb-1 0.0769 0.1545 1
Echinococcus multilocularis lamin 0.0026 0.002 0.002
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0065 0.01 0.041
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0031 0.0031 0.008
Schistosoma mansoni opsin-like receptor 0.0031 0.0031 0.0045
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0228 0.0434 0.0434
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0001 0.0001
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0031 0.0031 0.0045
Leishmania major heat shock protein 83-1 0.0033 0.0034 0.013
Brugia malayi MH1 domain containing protein 0.0034 0.0036 0.0228
Trypanosoma cruzi cruzipain precursor, putative 0.0062 0.0094 0.0382
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Echinococcus multilocularis FTZ F1 alpha 0.0103 0.0179 0.0178
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0089 0.1642
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0009 0.0009
Plasmodium vivax diacylglycerol kinase, putative 0.0073 0.0116 0.3744
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0065 0.0099 0.0258
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0065 0.01 0.0223
Onchocerca volvulus 0.0031 0.0031 0.0335
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Echinococcus multilocularis Diacylglycerol kinase zeta 0.0073 0.0116 0.0116
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0112 0.0163
Onchocerca volvulus 0.0018 0.0002 0.0014
Giardia lamblia Phosphoglycerate kinase 0.0167 0.0308 1
Onchocerca volvulus 0.0031 0.0031 0.0335
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0084 0.0138 0.4189
Trichomonas vaginalis diacylglycerol kinase, putative 0.0073 0.0116 0.2135
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.006 0.0089 0.1642
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0148 0.027 0.8698
Echinococcus multilocularis tumor protein p63 0.067 0.1342 0.1342
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0043 0.0055 0.0104
Schistosoma mansoni hypothetical protein 0.012 0.0212 0.0309
Brugia malayi intermediate filament protein 0.0026 0.002 0.0123
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0105 0.0181 0.0435
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0065 0.01 0.041
Echinococcus granulosus heat shock protein 0.0033 0.0034 0.0049
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0081 0.0133 0.0193
Loa Loa (eye worm) hypothetical protein 0.0049 0.0066 0.0173
Brugia malayi 6-phosphofructokinase 0.0113 0.0198 0.1273
Brugia malayi Pre-SET motif family protein 0.0035 0.0038 0.0242
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0081 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.0124 0.0222 0.058
Trypanosoma brucei DNA polymerase IV, putative 0.011 0.0192 0.079
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0111 0.0193 0.6071
Schistosoma mansoni hypothetical protein 0.0017 0.0001 0.0001
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0017 0.0505
Brugia malayi Patched family protein 0.0018 0.0002 0.0008
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Trypanosoma brucei DNA polymerase kappa, putative 0.0117 0.0206 0.0845
Echinococcus granulosus Diacylglycerol kinase zeta 0.0073 0.0116 0.0168
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0094 0.0382
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0031 0.0044
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0029 0.0513
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0059 0.0087 0.0087
Schistosoma mansoni amine GPCR 0.0031 0.0031 0.0045
Schistosoma mansoni histamine h1 receptor 0.0031 0.0031 0.0045
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0099 0.0404
Loa Loa (eye worm) oxidoreductase 0.0043 0.0055 0.0144
Brugia malayi steroid hormone receptor 0.0103 0.0179 0.115
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0031 0.0045
Schistosoma mansoni hypothetical protein 0.0243 0.0466 0.0677
Brugia malayi Patched family protein 0.0018 0.0002 0.0008
Loa Loa (eye worm) hypothetical protein 0.0069 0.0108 0.0283
Echinococcus multilocularis dro:myosuppressin receptor 0.0031 0.0031 0.003
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0049 0.0066 0.0096
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0005
Echinococcus granulosus ferritin 0.0027 0.0022 0.0032
Mycobacterium tuberculosis Conserved hypothetical protein 0.063 0.1261 0.3278
Brugia malayi Patched family protein 0.0018 0.0002 0.0008
Trypanosoma cruzi DNA polymerase kappa, putative 0.0117 0.0206 0.0845
Echinococcus granulosus allatostatin A receptor 0.0031 0.0031 0.0044
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0029 0.0513
Onchocerca volvulus 0.0018 0.0002 0.0014
Leishmania major heat shock protein 83-1 0.0033 0.0034 0.013
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0031 0.0031 0.003
Schistosoma mansoni amine GPCR 0.0031 0.0031 0.0045
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0043
Giardia lamblia DNA damage repair protein 0.0028 0.0024 0.0446
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0052 0.0073 0.0105
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0029 0.0025 0.0795
Echinococcus multilocularis neuropeptide FF receptor 2 0.0031 0.0031 0.003
Brugia malayi beta-lactamase 0.0071 0.0112 0.0721
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0167 0.0308 0.077
Schistosoma mansoni hypothetical protein 0.012 0.0212 0.0309
Plasmodium vivax DNA repair protein REV1, putative 0.0028 0.0024 0.0746
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0083 0.0137 0.0198
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0049 0.0066 0.0066
Plasmodium falciparum heat shock protein 90 0.0033 0.0034 0.1085
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0103 0.0179 0.0259
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0032 0.0032 0.0581
Brugia malayi hypothetical protein 0.0031 0.0031 0.0192
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0055 0.0079 0.2162
Echinococcus multilocularis G-protein coupled receptor, putative 0.0031 0.0031 0.003
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0228 0.0434 0.0631
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0011 0.004
Trypanosoma brucei DNA polymerase kappa, putative 0.0117 0.0206 0.0845
Loa Loa (eye worm) transcription factor SMAD2 0.0501 0.0995 0.2608
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0024 0.0095
Leishmania major heat shock protein 83-1 0.0033 0.0034 0.013
Trichomonas vaginalis set domain proteins, putative 0.0239 0.0456 0.8454
Echinococcus multilocularis orexin receptor type 2 0.0031 0.0031 0.003
Loa Loa (eye worm) hypothetical protein 0.0049 0.0066 0.0173
Brugia malayi hypothetical protein 0.0025 0.0017 0.01
Brugia malayi CXXC zinc finger family protein 0.0265 0.051 0.3299
Plasmodium vivax acyl-CoA synthetase, putative 0.0111 0.0193 0.6259
Toxoplasma gondii heat shock protein HSP90 0.0033 0.0034 0.0327
Brugia malayi Carboxy-terminal domain RNA polymerase II polypeptide A smallphosphatase 1 0.0025 0.0017 0.0106
Toxoplasma gondii Dullard family phosphatase domain-containing protein 0.0025 0.0017 0.0161
Echinococcus granulosus neuropeptide receptor 0.0031 0.0031 0.0044
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0103 0.0179 0.115
Loa Loa (eye worm) hypothetical protein 0.0043 0.0055 0.0144
Brugia malayi ecdysone receptor 0.0049 0.0066 0.0423
Echinococcus multilocularis transcription factor Dp 1 0.0037 0.0043 0.0043
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0243 0.0466 0.0676
Trichomonas vaginalis heat shock protein, putative 0.0026 0.002 0.0361
Brugia malayi hypothetical protein 0.0081 0.0133 0.0857
Brugia malayi follicle stimulating hormone receptor 0.0031 0.0031 0.0192
Onchocerca volvulus 0.0073 0.0116 0.1299
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0043 0.0055 0.0104
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0055 0.0078 0.0205
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0031 0.0044
Schistosoma mansoni 6-phosphofructokinase 0.0113 0.0198 0.0287
Onchocerca volvulus 0.0031 0.0031 0.0335
Loa Loa (eye worm) hypothetical protein 0.0052 0.0073 0.0189
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0031 0.0031 0.003
Echinococcus granulosus rhodopsin orphan GPCR 0.0031 0.0031 0.0044
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0008 0.0019
Loa Loa (eye worm) latrophilin receptor protein 2 0.0243 0.0466 0.122
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0103 0.0179 0.0259
Trypanosoma brucei DNA polymerase kappa, putative 0.0117 0.0206 0.0845
Echinococcus granulosus fmrfamide receptor 0.0031 0.0031 0.0044
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0067 0.0104 0.015
Schistosoma mansoni lamin 0.0026 0.002 0.0029
Trypanosoma brucei Diacylglycerol kinase catalytic domain containing protein, putative 0.0073 0.0116 0.0475
Brugia malayi latrophilin 2 splice variant baaae 0.0526 0.1046 0.6764
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0103 0.0179 0.0178
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Brugia malayi putative neuropeptide receptor NPR1 0.0031 0.0031 0.0192
Leishmania major heat shock protein 83-1 0.0033 0.0034 0.013
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0043 0.0055 0.0055
Echinococcus granulosus histone acetyltransferase KAT2B 0.0088 0.0148 0.0214
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0059 0.0087 0.0356
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0031 0.0045
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0081 0.0132 0.0191
Trypanosoma brucei heat shock protein 90, putative 0.0033 0.0034 0.0138
Giardia lamblia Heat shock protein HSP 90-alpha 0.0026 0.002 0.0329
Entamoeba histolytica diacylglycerol kinase, putative 0.0073 0.0116 0.0277
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0112 0.0163
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0017 0.0001 0.0001
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0043 0.0055 0.0224
Toxoplasma gondii isocitrate dehydrogenase 0.0065 0.01 0.0976
Trypanosoma cruzi ISWI complex protein 0.0028 0.0023 0.0092
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0295 0.0571 0.0829
Schistosoma mansoni neuropeptide F-like receptor 0.0031 0.0031 0.0045
Entamoeba histolytica acetyltransferase, GNAT family 0.0079 0.0128 0.0309
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0059 0.0087 0.0228
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.0083 0.0337
Schistosoma mansoni zinc finger protein 0.0049 0.0066 0.0096
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0097 0.0166 0.0672
Brugia malayi hypothetical protein 0.0031 0.0031 0.0192
Schistosoma mansoni ferritin light chain 0.0027 0.0022 0.0032
Trypanosoma cruzi DNA polymerase eta, putative 0.0079 0.0129 0.0529
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0043 0.0055 0.0104
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.006 0.0089 0.1642
Echinococcus multilocularis neuropeptide Y receptor 0.0031 0.0031 0.003
Brugia malayi Nuclear hormone receptor-like 1 0.0103 0.0179 0.115
Loa Loa (eye worm) MH1 domain-containing protein 0.0034 0.0036 0.0094
Brugia malayi isocitrate dehydrogenase 0.0065 0.01 0.0644
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0089 0.1642
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0005
Schistosoma mansoni dpf3 0.0017 0.0001 0.0001
Echinococcus granulosus fetal alzheimer antigen falz 0.0037 0.0042 0.0061
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0083 0.0137 0.0136
Echinococcus granulosus g protein coupled receptor 0.0031 0.0031 0.0044
Mycobacterium ulcerans acyl-CoA synthetase 0.0043 0.0055 0.0104
Echinococcus granulosus neuropeptides capa receptor 0.0031 0.0031 0.0044
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0073 0.0116 0.0475
Trichomonas vaginalis sphingosine kinase, putative 0.0073 0.0116 0.2135
Loa Loa (eye worm) hypothetical protein 0.0233 0.0445 0.1167
Trypanosoma brucei DNA polymerase kappa, putative 0.0117 0.0206 0.0845
Schistosoma mansoni intermediate filament proteins 0.0026 0.002 0.0029
Leishmania major heat shock protein 83-1 0.0033 0.0034 0.013
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Toxoplasma gondii patched family protein 0.0018 0.0002 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0103 0.0179 0.115
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0243 0.0466 0.0465
Brugia malayi Endoplasmin precursor 0.0033 0.0034 0.0216
Trypanosoma cruzi hypothetical protein, conserved 0.0025 0.0017 0.0068
Plasmodium falciparum DNA repair protein REV1, putative 0.0028 0.0024 0.0746
Echinococcus multilocularis Niemann Pick C1 protein 0.029 0.0562 0.0561
Echinococcus granulosus hypothetical protein 0.0031 0.0031 0.0044
Schistosoma mansoni diacylglycerol kinase theta 0.0073 0.0116 0.0169
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0002
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0049 0.0066 0.0066
Schistosoma mansoni cpg binding protein 0.0265 0.051 0.0742
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0031 0.0031 0.0192
Schistosoma mansoni hypothetical protein 0.0081 0.0133 0.0194
Onchocerca volvulus 0.0031 0.0031 0.0335
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0103 0.0179 0.115
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0059 0.0087 0.0356
Brugia malayi photoreceptor-specific nuclear receptor 0.0103 0.0179 0.115
Loa Loa (eye worm) hypothetical protein 0.0152 0.0279 0.0731
Echinococcus granulosus neuropeptide FF receptor 2 0.0031 0.0031 0.0044
Onchocerca volvulus 0.0031 0.0031 0.0335
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0029 0.0605
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0039 0.0046 0.0067
Echinococcus granulosus Niemann Pick C1 protein 0.029 0.0562 0.0816
Loa Loa (eye worm) eye-specific diacylglycerol kinase 0.0073 0.0116 0.0303
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Mycobacterium ulcerans bacterioferritin BfrB 0.0027 0.0022 0.0017
Loa Loa (eye worm) G-protein coupled receptor 0.0031 0.0031 0.008
Loa Loa (eye worm) hypothetical protein 0.0103 0.0179 0.0467
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0148 0.027 0.067
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0103 0.0179 0.0178
Echinococcus granulosus Nuclear hormone receptor HR96 0.0049 0.0066 0.0096
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0009 0.0149
Trypanosoma brucei Sphingosine kinase 0.0073 0.0116 0.0475
Trypanosoma cruzi DNA damage repair protein, putative 0.0028 0.0024 0.0095
Onchocerca volvulus 0.0018 0.0002 0.0014
Brugia malayi Patched protein homolog 1 0.0018 0.0002 0.0008
Loa Loa (eye worm) DR-78 0.0049 0.0066 0.0173
Loa Loa (eye worm) steroid hormone receptor 0.0103 0.0179 0.0467
Loa Loa (eye worm) hypothetical protein 0.0103 0.0179 0.0467
Echinococcus multilocularis sphingosine kinase 1 0.1874 0.3814 0.3814
Mycobacterium ulcerans lipase LipD 0.0071 0.0112 0.0255
Mycobacterium ulcerans acyl-CoA synthetase 0.0148 0.027 0.067
Onchocerca volvulus 0.0031 0.0031 0.0335
Brugia malayi Serotonin receptor 0.0031 0.0031 0.0192
Echinococcus granulosus histone acetyltransferase myst3 0.0017 0.0001 0.0001
Plasmodium vivax hypothetical protein, conserved 0.0071 0.0112 0.3627
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Entamoeba histolytica acyl-CoA synthetase, putative 0.0148 0.027 0.0682
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0031 0.0031 0.003
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0005
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0029 0.0513
Echinococcus multilocularis allatostatin A receptor 0.0031 0.0031 0.003
Loa Loa (eye worm) MH2 domain-containing protein 0.0034 0.0036 0.0094
Loa Loa (eye worm) ceramide kinase 0.0073 0.0116 0.0303
Echinococcus granulosus neuropeptide receptor 0.0031 0.0031 0.0044
Onchocerca volvulus 0.0148 0.027 0.3039
Brugia malayi hypothetical protein 0.0031 0.0031 0.0192
Entamoeba histolytica deoxycytidyl transferase, putative 0.0091 0.0152 0.0372
Echinococcus multilocularis g protein coupled receptor 0.0031 0.0031 0.003
Echinococcus granulosus biogenic amine 5HT receptor 0.0031 0.0031 0.0044
Brugia malayi diacylglycerol kinase 0.0073 0.0116 0.0745
Brugia malayi Patched family protein 0.0018 0.0002 0.0008
Brugia malayi nuclear receptor NHR-88 0.0049 0.0066 0.0423
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0148 0.027 0.067
Leishmania major heat shock protein 83-1 0.0033 0.0034 0.013
Brugia malayi Bromodomain containing protein 0.0096 0.0163 0.1047
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0168 0.0312 0.1282
Schistosoma mansoni requim req/dpf2 0.0017 0.0001 0.0001
Schistosoma mansoni steroid hormone receptor ad4bp 0.0103 0.0179 0.0259
Echinococcus multilocularis Zinc finger, DBF type 0.0017 0.0001 0.0001
Schistosoma mansoni sphingosine kinase A B 0.1874 0.3814 0.5541
Echinococcus multilocularis fmrfamide receptor 0.0031 0.0031 0.003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0103 0.0179 0.0467
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.1197 0.2424 1
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0059 0.0087 0.0188
Brugia malayi Ceramide kinase 0.0073 0.0116 0.0745
Trypanosoma brucei unspecified product 0.0063 0.0095 0.0386
Brugia malayi MH1 domain containing protein 0.0034 0.0036 0.0228
Entamoeba histolytica hypothetical protein 0.0081 0.0133 0.0323
Mycobacterium tuberculosis Conserved hypothetical protein 0.0091 0.0152 0.036
Brugia malayi SET domain containing protein 0.0024 0.0015 0.0091
Schistosoma mansoni ferritin 0.0027 0.0022 0.0032
Leishmania major cathepsin L-like protease 0.0062 0.0094 0.0375
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0065 0.01 0.01
Brugia malayi Dopamine receptor protein 1 0.0031 0.0031 0.0192
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0228 0.0434 0.063
Schistosoma mansoni smad 0.0034 0.0036 0.0053
Loa Loa (eye worm) neuropeptide F receptor 0.0031 0.0031 0.008
Echinococcus multilocularis g-protein coupled receptor 0.0031 0.0031 0.003
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0024 0.0016 0.0145
Schistosoma mansoni hypothetical protein 0.0017 0.0001 0.0001
Echinococcus multilocularis muscleblind protein 0.0147 0.0268 0.0267
Echinococcus multilocularis neuropeptide receptor A26 0.0979 0.1975 0.1975
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0 0.0001
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0105 0.0181 0.0435
Plasmodium vivax heat shock protein 86, putative 0.0033 0.0034 0.1085
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0031 0.0031 0.003
Echinococcus multilocularis TAF3 RNA polymerase II, TATA box binding protein 0.0017 0.0001 0.0001
Schistosoma mansoni smad1 5 8 and 0.0034 0.0036 0.0053
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0029 0.0272
Echinococcus multilocularis beta LACTamase domain containing family member 0.0071 0.0112 0.0112
Toxoplasma gondii diacylglycerol kinase, putative 0.0073 0.0116 0.113
Echinococcus multilocularis smad 0.0034 0.0036 0.0036
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0103 0.0179 0.0259
Toxoplasma gondii patched family protein 0.0018 0.0002 0.0012
Echinococcus multilocularis histone acetyltransferase myst4 0.0017 0.0001 0.0001
Brugia malayi polk-prov protein 0.0054 0.0077 0.0494
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0027 0.0022 0.0017
Brugia malayi hypothetical protein 0.0031 0.0031 0.0192
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0005
Schistosoma mansoni hypothetical protein 0.0025 0.0017 0.0024
Mycobacterium leprae conserved hypothetical protein 0.0071 0.0112 0.3306
Schistosoma mansoni fyve-containing 0.0017 0.0001 0.0001
Leishmania major mitochondrial DNA polymerase beta 0.1197 0.2424 1
Schistosoma mansoni opsin-like receptor 0.0031 0.0031 0.0045
Brugia malayi sulfakinin receptor protein 0.0031 0.0031 0.0192
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0103 0.0179 0.0259
Leishmania major acetyl-CoA synthetase, putative 0.0043 0.0055 0.0216
Brugia malayi Eye-specific diacylglycerol kinase 0.0073 0.0116 0.0745
Schistosoma mansoni hypothetical protein 0.3369 0.6883 1
Trypanosoma brucei DNA polymerase IV, putative 0.0117 0.0206 0.0845
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0103 0.0179 0.0259
Trypanosoma brucei DNA polymerase kappa, putative 0.0069 0.0108 0.0441
Brugia malayi nuclear hormone receptor 0.0049 0.0066 0.0423
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0198 0.0491
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0031 0.0045
Giardia lamblia Grp94/Hsp90 0.0026 0.002 0.0329
Plasmodium falciparum diacylglycerol kinase, putative 0.0073 0.0116 0.3744
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0103 0.0179 0.115
Echinococcus multilocularis heat shock protein 90 0.0026 0.002 0.002
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0031 0.0031 0.008
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0043 0.0055 0.1356
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0055 0.0078 0.0078
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0148 0.027 0.067
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0198 0.3649
Plasmodium falciparum SNF2 helicase, putative 0.0017 0.0001 0.00000000038261
Echinococcus granulosus serotonin receptor 0.0031 0.0031 0.0044
Mycobacterium ulcerans phosphoglycerate kinase 0.0167 0.0308 0.077
Schistosoma mansoni transcription factor LCR-F1 0.0081 0.0133 0.0194
Echinococcus multilocularis protein patched 0.0124 0.0222 0.0221
Echinococcus multilocularis PHD finger protein 14 0.0017 0.0001 0.0001
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0029 0.09
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0005
Schistosoma mansoni hypothetical protein 0.0017 0.0001 0.0001
Echinococcus multilocularis Carboxy terminal domain RNA polymerase II 0.0025 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0111 0.0193 0.0506
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0071 0.0112 0.0255
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0031 0.0031 0.003
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0002
Leishmania major heat shock protein 83-1 0.0033 0.0034 0.013
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Brugia malayi Patched family protein 0.0018 0.0002 0.0008
Mycobacterium tuberculosis Diacylglycerol kinase 0.0073 0.0116 0.0264
Echinococcus multilocularis musashi 0.0026 0.002 0.002
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0769 0.1545 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.021 0.0398 0.1044
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0005
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0029 0.0442
Leishmania major hypothetical protein, conserved 0.0071 0.0112 0.0452
Trichomonas vaginalis sphingosine kinase, putative 0.0073 0.0116 0.2135
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Schistosoma mansoni myst-related protein 0.0033 0.0034 0.005
Giardia lamblia Heat shock protein HSP 90-alpha 0.0033 0.0034 0.0795
Loa Loa (eye worm) acetyltransferase 0.0295 0.0572 0.15
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0103 0.0179 0.115
Brugia malayi hypothetical protein 0.0031 0.0031 0.0192
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0031 0.0031 0.0045
Loa Loa (eye worm) hypothetical protein 0.0038 0.0043 0.0113
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Leishmania major phosphoglycerate kinase B, cytosolic 0.0167 0.0308 0.1261
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.002 0.0052
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0065 0.0099 0.0396
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0005
Schistosoma mansoni hypothetical protein 0.0031 0.0031 0.0045
Schistosoma mansoni hypothetical protein 0.0031 0.0031 0.0045
Echinococcus granulosus microtubule associated protein 2 0.2867 0.5853 0.8503
Loa Loa (eye worm) nuclear factor I 0.0019 0.0005 0.0012
Trypanosoma brucei heat shock protein, putative 0.0033 0.0034 0.0138
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0043 0.0055 0.0224
Echinococcus multilocularis 0.0025 0.0017 0.0017
Toxoplasma gondii patched family protein 0.0018 0.0002 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0023 0.0414
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0094 0.0382
Plasmodium falciparum zinc finger protein, putative 0.0033 0.0034 0.108
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0005
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0027 0.0106
Brugia malayi hypothetical protein 0.0018 0.0002 0.0008
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0012
Schistosoma mansoni DNA polymerase eta 0.0142 0.0258 0.0374
Schistosoma mansoni hypothetical protein 0.0031 0.0031 0.0045
Trypanosoma cruzi DNA polymerase kappa, putative 0.0117 0.0206 0.0845
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Loa Loa (eye worm) hypothetical protein 0.0103 0.0179 0.0467
Brugia malayi hypothetical protein 0.0018 0.0002 0.0008
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0029 0.0025 0.0795
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0031 0.0031 0.0192
Schistosoma mansoni survival motor neuron protein 0.0048 0.0064 0.0093
Schistosoma mansoni DNA polymerase IV / kappa 0.0028 0.0024 0.0035
Onchocerca volvulus 0.0031 0.0031 0.0335
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0049 0.0066 0.0066
Entamoeba histolytica hypothetical protein 0.0024 0.0015 0.0012
Loa Loa (eye worm) heat shock protein 90 0.0033 0.0034 0.0089
Brugia malayi phosphofructokinase 0.0113 0.0198 0.1273
Echinococcus multilocularis L aminoadipate semialdehyde 0.0086 0.0143 0.0142
Brugia malayi Smad1 0.0034 0.0036 0.0228
Trypanosoma brucei diacylglycerol kinase, putative 0.0073 0.0116 0.0475
Brugia malayi glutaminase DH11.1 0.0279 0.054 0.3488
Loa Loa (eye worm) bromodomain containing protein 0.0024 0.0016 0.0042
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0103 0.0179 0.115
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0029 0.0272
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0113 0.0198 0.0811
Echinococcus granulosus Carboxy terminal domain RNA polymerase II 0.0025 0.0017 0.0025
Schistosoma mansoni RAR-like nuclear receptor 0.0103 0.0179 0.0259
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0103 0.0179 0.2005
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0025 0.0017 0.0304
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0059 0.0087 0.2805
Trichomonas vaginalis bmru protein, putative 0.0073 0.0116 0.2135
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0031 0.0031 0.0045
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0017 0.0064
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Mycobacterium ulcerans 6-phosphofructokinase 0.0113 0.0198 0.0479
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0103 0.0179 0.0259
Echinococcus multilocularis dna polymerase eta 0.0142 0.0258 0.0257
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0112 0.046
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0026 0.002 0.0161
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0065 0.01 0.0146
Schistosoma mansoni amine GPCR 0.0031 0.0031 0.0045
Brugia malayi hypothetical protein 0.0018 0.0002 0.0008
Plasmodium falciparum lipid/sterol:H+ symporter 0.0018 0.0002 0.0041
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0043 0.0055 0.0534
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0031 0.0031 0.003
Schistosoma mansoni lamin 0.0026 0.002 0.0029
Plasmodium vivax patched family protein, putative 0.0018 0.0002 0.0041
Loa Loa (eye worm) hypothetical protein 0.0049 0.0066 0.0173
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0025 0.0017 0.0025
Trichomonas vaginalis heat shock protein, putative 0.0033 0.0034 0.0619
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0031 0.0031 0.0045
Echinococcus granulosus importin subunit beta 1 0.0029 0.0027 0.0038
Loa Loa (eye worm) hypothetical protein 0.0049 0.0066 0.0173
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0043 0.0055 0.0104
Loa Loa (eye worm) isocitrate dehydrogenase 0.0065 0.01 0.0262
Echinococcus multilocularis sex peptide receptor 0.0031 0.0031 0.003
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.0104 0.015
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0088 0.0148 0.4776
Loa Loa (eye worm) hypothetical protein 0.0086 0.0143 0.0373
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0011 0.0027
Schistosoma mansoni hypothetical protein 0.0017 0.0001 0.0001
Echinococcus multilocularis protein dispatched 1 0.0142 0.0258 0.0257
Trichomonas vaginalis bmru protein, putative 0.0073 0.0116 0.2135
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0148 0.027 0.067
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0049 0.0066 0.0423
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0059 0.0087 0.0348
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0088 0.0148 0.1441
Trypanosoma brucei Heat shock protein 83, putative 0.0033 0.0034 0.0138
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0084 0.0138 0.02
Schistosoma mansoni endoplasmin 0.0033 0.0034 0.005
Brugia malayi Isocitrate dehydrogenase 0.0065 0.01 0.0644
Loa Loa (eye worm) hypothetical protein 0.0031 0.0031 0.008
Loa Loa (eye worm) hypothetical protein 0.0071 0.0112 0.0294
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0244 0.0468 0.1226
Echinococcus granulosus phd finger protein 12 0.0017 0.0001 0.0001
Echinococcus granulosus survival motor neuron protein 1 0.0233 0.0445 0.0646
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0037 0.0043 0.0072
Onchocerca volvulus Bile acid receptor homolog 0.0103 0.0179 0.2005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0031 0.0045
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0103 0.0179 0.0259
Trypanosoma brucei DNA polymerase IV, putative 0.0117 0.0206 0.0845
Echinococcus granulosus lysine specific demethylase 5A 0.0017 0.0001 0.0001
Brugia malayi Patched family protein 0.0018 0.0002 0.0008
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0111 0.0193 0.0467
Echinococcus granulosus thyroid hormone receptor alpha 0.0049 0.0066 0.0096
Trypanosoma cruzi diacylglycerol kinase, putative 0.0073 0.0116 0.0475
Loa Loa (eye worm) patched family protein 0.0018 0.0002 0.0005
Onchocerca volvulus 0.0031 0.0031 0.0335
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0043 0.0055 0.0104
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0097 0.0166 0.0394
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0084 0.0138 0.4189
Mycobacterium tuberculosis Probable lipase LipD 0.0071 0.0112 0.0255
Brugia malayi Melatonin receptor type 1A 0.0031 0.0031 0.0192
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0043 0.0055 0.0104
Schistosoma mansoni hypothetical protein 0.0526 0.1046 0.1519
Mycobacterium ulcerans acyl-CoA synthetase 0.0148 0.027 0.067
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0065 0.01 0.041
Echinococcus granulosus dro:myosuppressin receptor 0.0031 0.0031 0.0044
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0228 0.0434 0.1138
Plasmodium falciparum diacylglycerol kinase, putative 0.0073 0.0116 0.3744
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0065 0.01 0.0402
Brugia malayi Niemann-Pick C1 protein precursor 0.029 0.0562 0.3631
Trichomonas vaginalis endoplasmin, putative 0.002 0.0008 0.0129
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0103 0.0179 0.115
Brugia malayi tailless protein 0.0049 0.0066 0.0423
Entamoeba histolytica phosphofructokinase, putative 0.0113 0.0198 0.0491
Schistosoma mansoni nuclear receptor 0.0049 0.0066 0.0096
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0168 0.0312 0.1282
Trypanosoma brucei DNA polymerase kappa, putative 0.0117 0.0206 0.0845
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0103 0.0179 0.0467
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0084 0.0138 0.0323
Mycobacterium tuberculosis Conserved protein 0.0071 0.0112 0.0255
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0031 0.0031 0.0044
Onchocerca volvulus 0.0031 0.0031 0.0335
Brugia malayi Muscleblind-like protein 0.0147 0.0268 0.1728
Brugia malayi Dopamine receptor 0.0031 0.0031 0.0192
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0103 0.0179 0.0259
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0031 0.0031 0.0045
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0094 0.0382
Schistosoma mansoni microtubule-associated protein tau 0.2867 0.5853 0.8504
Brugia malayi RNA, U transporter 1 0.0084 0.0138 0.0888
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0094 0.0382
Echinococcus granulosus expressed conserved protein 0.0272 0.0526 0.0763
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0315 0.0612 0.1604
Onchocerca volvulus 0.0265 0.051 0.5753
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0011 0.0015
Plasmodium vivax SET domain protein, putative 0.0035 0.0038 0.1215
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0038 0.0366
Plasmodium falciparum acyl-CoA synthetase 0.0111 0.0193 0.6259
Mycobacterium ulcerans hypothetical protein 0.0028 0.0024 0.0022
Loa Loa (eye worm) hypothetical protein 0.0026 0.002 0.0053
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0026 0.002 0.0072
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0026 0.002 0.0012
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0011 0.0314
Brugia malayi Patched family protein 0.0018 0.0002 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0117 0.0206 0.0845
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0084 0.0138 0.4468
Schistosoma mansoni thyroid hormone receptor 0.0103 0.0179 0.0259
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0031 0.0031 0.003
Echinococcus multilocularis ecdysone induced protein 78C 0.0103 0.0179 0.0178
Brugia malayi nuclear receptor NHR-67 0.0049 0.0066 0.0423
Schistosoma mansoni PHD zinc finger protein XAP135-related 0.0017 0.0001 0.0001
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0084 0.0138 0.0323
Echinococcus multilocularis nuclear receptor nhr 48 0.0049 0.0066 0.0066
Loa Loa (eye worm) glutaminase 2 0.0279 0.054 0.1414
Brugia malayi AKH receptor 0.0031 0.0031 0.0192
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0027 0.0022 0.0218
Echinococcus granulosus biogenic amine 5HT receptor 0.0031 0.0031 0.0044
Echinococcus multilocularis Smad4 0.0034 0.0036 0.0036
Brugia malayi AMP-binding enzyme family protein 0.0148 0.027 0.1743
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0049 0.0066 0.0173
Echinococcus granulosus phd finger protein 10 0.0017 0.0001 0.0001
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0148 0.027 0.067
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0001 0.0001
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0016 0.048
Onchocerca volvulus 0.0071 0.0112 0.1258
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0112 0.2068
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0059 0.0087 0.0188
Loa Loa (eye worm) hypothetical protein 0.0049 0.0066 0.0173
Leishmania major ATP-dependent phosphofructokinase 0.0113 0.0198 0.0804
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0088 0.0148 0.1441
Mycobacterium ulcerans acyl-CoA synthetase 0.0043 0.0055 0.0104
Schistosoma mansoni zinc finger protein 0.0017 0.0001 0.0001
Echinococcus multilocularis heat shock protein 90 0.0033 0.0034 0.0034
Echinococcus multilocularis neuropeptides capa receptor 0.0031 0.0031 0.003
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0031 0.0031 0.008
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0025 0.0017 0.0304
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0167 0.0308 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0031 0.0045
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0084 0.0138 0.1348
Schistosoma mansoni ferritin 0.0027 0.0022 0.0032
Trypanosoma brucei heat shock protein, putative 0.0033 0.0034 0.0138
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0031 0.0031 0.003
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0049 0.0066 0.0066
Brugia malayi Nuclear hormone receptor E75 0.0049 0.0066 0.0423
Schistosoma mansoni hypothetical protein 0.0701 0.1406 0.2043
Echinococcus multilocularis GPCR, family 2 0.0243 0.0466 0.0465
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0009 0.0149
Onchocerca volvulus 0.0018 0.0002 0.0014
Brugia malayi Serotonin receptor 0.0031 0.0031 0.0192
Schistosoma mansoni hypothetical protein 0.0031 0.0031 0.0045
Schistosoma mansoni hypothetical protein 0.0048 0.0064 0.0093
Echinococcus multilocularis phd finger protein 10 0.0017 0.0001 0.0001
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0065 0.01 0.0145
Echinococcus multilocularis neuropeptide receptor 0.0031 0.0031 0.003
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0031 0.0031 0.0192
Toxoplasma gondii exonuclease III APE 0.0059 0.0087 0.0846
Schistosoma mansoni ap endonuclease 0.0059 0.0087 0.0127
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0091 0.0152 0.0152
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0124 0.0222 0.058
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0005
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0043 0.0055 0.0104
Schistosoma mansoni sphingoid long chain base kinase 0.1874 0.3814 0.5541
Brugia malayi Steroid receptor seven-up type 2 0.0103 0.0179 0.115
Echinococcus multilocularis PHD and RING finger domain containing protein 1 0.0017 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0005
Leishmania major DNA polymerase eta, putative 0.0079 0.0129 0.0521
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0086 0.0143 0.0916
Onchocerca volvulus Protein ultraspiracle homolog 0.0103 0.0179 0.2005
Echinococcus granulosus intermediate filament protein 0.0026 0.002 0.0029
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0011 0.004
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0043 0.0055 0.0224
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0055 0.0079 0.0166
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0011 0.001
Brugia malayi Patched related family protein 10 0.0018 0.0002 0.0008
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0112 0.2068
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0064 0.0407
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0167 0.0308 0.1268
Leishmania major hypothetical protein, conserved 0.0025 0.0017 0.006
Brugia malayi heat shock protein 90 0.0033 0.0034 0.0216
Plasmodium vivax diacylglycerol kinase, putative 0.0073 0.0116 0.3744
Loa Loa (eye worm) hypothetical protein 0.0049 0.0066 0.0173
Schistosoma mansoni importin beta-1 0.0029 0.0027 0.0039
Loa Loa (eye worm) hypothetical protein 0.0073 0.0116 0.0303
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0017 0.0001 0.0001
Schistosoma mansoni acetyl-CoA synthetase 0.0043 0.0055 0.008
Echinococcus multilocularis neuropeptide Y receptor 0.0031 0.0031 0.003
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0029 0.0513
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0043 0.0055 0.0104
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0031 0.0031 0.0045
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0005
Schistosoma mansoni peptidase Clp (S14 family) 0.0084 0.0138 0.0201
Schistosoma mansoni biogenic amine receptor 0.0031 0.0031 0.0045
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0029 0.0513
Echinococcus multilocularis rhodopsin orphan GPCR 0.0031 0.0031 0.003
Onchocerca volvulus Protein patched homolog 0.0018 0.0002 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0089 0.1642
Trypanosoma cruzi DNA damage repair protein, putative 0.0028 0.0024 0.0095
Echinococcus granulosus heat shock protein 90 0.0026 0.002 0.0029
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0243 0.0466 0.0465
Entamoeba histolytica heat shock protein 90, putative 0.0033 0.0034 0.0062
Loa Loa (eye worm) hypothetical protein 0.1874 0.3814 1
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0061 0.0092 0.0374
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0029 0.0442
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0167 0.0308 0.3018
Toxoplasma gondii SWI2/SNF2-containing PHD finger protein 0.0017 0.0001 0.00000000011546
Echinococcus granulosus Nuclear hormone receptor HR96 0.0049 0.0066 0.0096
Loa Loa (eye worm) hypothetical protein 0.0073 0.0116 0.0303
Trypanosoma brucei DNA damage repair protein, putative 0.0028 0.0024 0.0095
Mycobacterium ulcerans acyl-CoA synthetase 0.0043 0.0055 0.0104
Schistosoma mansoni hypothetical protein 0.0017 0.0001 0.0001
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0031 0.0031 0.0335
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0566 0.1129 0.4653
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0065 0.01 0.041
Brugia malayi conserved hypotetical protein 0.0049 0.0066 0.0423
Trypanosoma brucei heat shock protein, putative 0.0033 0.0034 0.0138
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0029 0.0025 0.0331
Trichomonas vaginalis phosphofructokinase, putative 0.0113 0.0198 0.3649
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0002
Schistosoma mansoni neuropeptide receptor 0.0031 0.0031 0.0045
Loa Loa (eye worm) glutaminase 0.0279 0.054 0.1414
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0005
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0043 0.0055 0.0118
Trypanosoma cruzi heat shock protein 85, putative 0.0033 0.0034 0.0138
Mycobacterium ulcerans acyl-CoA synthetase 0.0043 0.0055 0.0104
Entamoeba histolytica diacylglycerol kinase, putative 0.0073 0.0116 0.0277
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0017 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0116 0.2135
Loa Loa (eye worm) hypothetical protein 0.0018 0.0002 0.0005
Onchocerca volvulus 0.0031 0.0031 0.0335
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0027 0.0106
Brugia malayi AMP-binding enzyme family protein 0.0043 0.0055 0.0352
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0011 0.0095
Treponema pallidum bacterioferrin (TpF1) 0.0027 0.0022 0.0218
Entamoeba histolytica diacylglycerol kinase, putative 0.0073 0.0116 0.0277
Brugia malayi Patched family protein 0.0018 0.0002 0.0008
Echinococcus granulosus neuropeptides capa receptor 0.0031 0.0031 0.0044
Leishmania major heat shock protein 83-1 0.0033 0.0034 0.013
Loa Loa (eye worm) hypothetical protein 0.0142 0.0258 0.0674
Trypanosoma brucei unspecified product 0.011 0.0192 0.079
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0105 0.0181 0.0435
Loa Loa (eye worm) hypothetical protein 0.0055 0.0078 0.0205
Schistosoma mansoni hypothetical protein 0.0701 0.1406 0.2043
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0116 0.0475
Mycobacterium ulcerans esterase/lipase LipP 0.0071 0.0112 0.0255
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0017 0.0152
Trichomonas vaginalis ferritin, putative 0.0027 0.0022 0.0392
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0031 0.0031 0.003
Trypanosoma cruzi heat shock protein 90, putative 0.0033 0.0034 0.0138

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 1.0418 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 14.1254 uM PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 14.581 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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