Detailed information for compound 156781

Basic information

Technical information
  • TDR Targets ID: 156781
  • Name: N-[2-[4-[[3-butyl-5-oxo-1-[2-(trifluoromethyl )phenyl]-1,2,4-triazol-4-yl]methyl]phenyl]phe nyl]sulfonylcyclopentanecarboxamide
  • MW: 626.689 | Formula: C32H33F3N4O4S
  • H donors: 1 H acceptors: 4 LogP: 6.78 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCCCc1nn(c(=O)n1Cc1ccc(cc1)c1ccccc1S(=O)(=O)NC(=O)C1CCCC1)c1ccccc1C(F)(F)F
  • InChi: 1S/C32H33F3N4O4S/c1-2-3-16-29-36-39(27-14-8-7-13-26(27)32(33,34)35)31(41)38(29)21-22-17-19-23(20-18-22)25-12-6-9-15-28(25)44(42,43)37-30(40)24-10-4-5-11-24/h6-9,12-15,17-20,24H,2-5,10-11,16,21H2,1H3,(H,37,40)
  • InChiKey: BPMHTBBVCZRJAP-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[2-[4-[[3-butyl-5-keto-1-[2-(trifluoromethyl)phenyl]-1,2,4-triazol-4-yl]methyl]phenyl]phenyl]sulfonylcyclopentanecarboxamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Angiotensin II type 2 (AT-2) receptor Starlite/ChEMBL References
Oryctolagus cuniculus Angiotensin II type 1a (AT-1a) receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Onchocerca volvulus Angiotensin II type 1a (AT-1a) receptor   359 aa 341 aa 23.2 %
Onchocerca volvulus E3 ubiquitin-protein ligase rpm-1 homolog Angiotensin II type 1a (AT-1a) receptor   359 aa 328 aa 20.7 %
Loa Loa (eye worm) neuropeptide F receptor Angiotensin II type 2 (AT-2) receptor   363 aa 356 aa 23.3 %
Onchocerca volvulus Angiotensin II type 2 (AT-2) receptor   363 aa 306 aa 22.5 %
Echinococcus granulosus thyrotropin releasing hormone receptor Angiotensin II type 2 (AT-2) receptor   363 aa 308 aa 22.1 %
Schistosoma mansoni peptide (allatostatin)-like receptor Angiotensin II type 2 (AT-2) receptor   363 aa 364 aa 20.9 %
Schistosoma japonicum ko:K04134 cholinergic receptor, invertebrate, putative Angiotensin II type 1a (AT-1a) receptor   359 aa 325 aa 20.9 %
Schistosoma japonicum Rhodopsin, putative Angiotensin II type 2 (AT-2) receptor   363 aa 341 aa 22.0 %
Echinococcus granulosus pyroglutamylated rfamide peptide receptor Angiotensin II type 2 (AT-2) receptor   363 aa 398 aa 18.3 %
Onchocerca volvulus Angiotensin II type 1a (AT-1a) receptor   359 aa 296 aa 23.0 %
Echinococcus granulosus tm gpcr rhodopsin Angiotensin II type 1a (AT-1a) receptor   359 aa 306 aa 21.9 %
Onchocerca volvulus Angiotensin II type 2 (AT-2) receptor   363 aa 311 aa 23.8 %
Echinococcus granulosus growth hormone secretagogue receptor type 1 Angiotensin II type 1a (AT-1a) receptor   359 aa 342 aa 22.2 %
Brugia malayi putative neuropeptide receptor NPR1 Angiotensin II type 1a (AT-1a) receptor   359 aa 295 aa 27.1 %
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily Angiotensin II type 1a (AT-1a) receptor   359 aa 306 aa 21.9 %
Echinococcus granulosus allatostatin A receptor Angiotensin II type 2 (AT-2) receptor   363 aa 340 aa 24.1 %
Echinococcus multilocularis G-protein coupled receptor, putative Angiotensin II type 1a (AT-1a) receptor   359 aa 307 aa 22.5 %
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor Angiotensin II type 1a (AT-1a) receptor   359 aa 346 aa 18.2 %
Brugia malayi GnHR receptor homolog Angiotensin II type 1a (AT-1a) receptor   359 aa 364 aa 20.3 %
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor Angiotensin II type 2 (AT-2) receptor   363 aa 398 aa 18.1 %
Onchocerca volvulus Angiotensin II type 1a (AT-1a) receptor   359 aa 313 aa 25.6 %
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor Angiotensin II type 1a (AT-1a) receptor   359 aa 364 aa 23.1 %
Echinococcus multilocularis neuropeptide receptor Angiotensin II type 2 (AT-2) receptor   363 aa 308 aa 21.4 %
Schistosoma mansoni adenoreceptor Angiotensin II type 2 (AT-2) receptor   363 aa 328 aa 22.0 %
Echinococcus multilocularis thyrotropin releasing hormone receptor Angiotensin II type 2 (AT-2) receptor   363 aa 308 aa 21.8 %
Schistosoma japonicum ko:K04209 neuropeptide Y receptor, invertebrate, putative Angiotensin II type 2 (AT-2) receptor   363 aa 310 aa 23.5 %
Onchocerca volvulus Angiotensin II type 1a (AT-1a) receptor   359 aa 399 aa 25.3 %
Loa Loa (eye worm) hypothetical protein Angiotensin II type 1a (AT-1a) receptor   359 aa 308 aa 27.3 %
Loa Loa (eye worm) hypothetical protein Angiotensin II type 1a (AT-1a) receptor   359 aa 335 aa 23.0 %
Echinococcus granulosus neuropeptide receptor Angiotensin II type 2 (AT-2) receptor   363 aa 306 aa 22.2 %
Onchocerca volvulus Angiotensin II type 2 (AT-2) receptor   363 aa 305 aa 21.6 %
Echinococcus multilocularis allatostatin A receptor Angiotensin II type 2 (AT-2) receptor   363 aa 342 aa 24.6 %
Brugia malayi ORL1-like opioid receptor Angiotensin II type 1a (AT-1a) receptor   359 aa 333 aa 21.3 %
Schistosoma mansoni opsin-like receptor Angiotensin II type 1a (AT-1a) receptor   359 aa 299 aa 25.1 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0074 0.0158
Trichomonas vaginalis mercuric reductase, putative 0.0051 0.0116 0.0247
Trypanosoma cruzi heat shock protein 90, putative 0.0097 0.0297 0.1017
Loa Loa (eye worm) hypothetical protein 0.0036 0.0054 0.0065
Trypanosoma cruzi major cysteine proteinase, putative 0.0097 0.0295 0.101
Toxoplasma gondii histone lysine methyltransferase SET1 0.0367 0.1358 0.9948
Loa Loa (eye worm) hypothetical protein 0.0039 0.0067 0.0082
Echinococcus granulosus inositol monophosphatase 1 0.0073 0.0203 0.02
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0073 0.0203 0.0431
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0111 0.035 0.0744
Echinococcus granulosus neuropeptide s receptor 0.0466 0.1748 0.1746
Plasmodium vivax unspecified product 0.0052 0.012 0.0823
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0011 0.0024
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0061 0.0154 0.02
Schistosoma mansoni hypothetical protein 0.0073 0.0203 0.02
Echinococcus multilocularis cpg binding protein 0.0204 0.0716 0.0713
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.004 0.0073 0.0155
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0061 0.0154 0.0151
Brugia malayi Cathepsin L-like precursor 0.0111 0.035 0.0463
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0026 0.0017 0.0036
Trypanosoma cruzi cysteine peptidase, putative 0.0157 0.0532 0.1845
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0051 0.0113 0.0145
Loa Loa (eye worm) acetyltransferase 0.0163 0.0557 0.074
Echinococcus multilocularis cathepsin L 0.0103 0.0319 0.0316
Schistosoma mansoni inositol monophosphatase 0.0073 0.0203 0.02
Echinococcus granulosus insulin receptor 0.0615 0.2338 0.2336
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0024 0.0008 0.0005
Plasmodium falciparum ataxin-2 like protein, putative 0.0075 0.0211 0.1493
Loa Loa (eye worm) cathepsin B 0.0265 0.0959 0.1281
Brugia malayi Immunoglobulin I-set domain containing protein 0.0024 0.0009 0.0005
Brugia malayi Matrixin family protein 0.0036 0.0054 0.0065
Schistosoma mansoni jumonji/arid domain-containing protein 0.0131 0.043 0.0427
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0033 0.007
Trichomonas vaginalis heat shock protein, putative 0.0057 0.0137 0.029
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0051 0.0113 0.0145
Loa Loa (eye worm) hypothetical protein 0.0176 0.0608 0.081
Brugia malayi photoreceptor-specific nuclear receptor 0.0061 0.0154 0.02
Brugia malayi AF-10 protein 0.0029 0.0028 0.003
Loa Loa (eye worm) heterochromatin protein 1 0.0069 0.0187 0.0244
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0043 0.0085 0.0106
Trypanosoma cruzi trypanothione reductase, putative 0.0148 0.0498 0.1724
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0143 0.0477 0.0474
Trichomonas vaginalis heat shock protein, putative 0.0083 0.0242 0.0513
Echinococcus granulosus epidermal growth factor receptor 0.1031 0.3974 0.3972
Loa Loa (eye worm) hypothetical protein 0.003 0.0034 0.0038
Echinococcus multilocularis neuropeptide receptor A26 0.0466 0.1748 0.1746
Echinococcus granulosus cathepsin b 0.0745 0.2848 0.2846
Schistosoma mansoni lamin 0.0026 0.0018 0.0015
Loa Loa (eye worm) CXXC zinc finger family protein 0.018 0.0622 0.0828
Loa Loa (eye worm) TK/INSR protein kinase 0.0615 0.2338 0.3133
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0439 0.1644 0.1642
Trypanosoma cruzi cruzipain precursor, putative 0.0157 0.0532 0.1845
Trichomonas vaginalis glucosylceramidase, putative 0.0798 0.3057 0.649
Echinococcus granulosus jumonji domain containing protein 0.0123 0.04 0.0397
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0078 0.0167
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0083 0.0242 0.0238
Schistosoma mansoni hypothetical protein 0.1732 0.6737 0.6736
Leishmania major heat shock protein 83-1 0.0097 0.0297 0.3056
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0025 0.0011 0.0008
Entamoeba histolytica cysteine protease, putative 0.0103 0.0319 0.3517
Loa Loa (eye worm) matrixin family protein 0.0086 0.0253 0.0332
Echinococcus multilocularis insulin receptor 0.0615 0.2338 0.2336
Brugia malayi Pre-SET motif family protein 0.0157 0.0532 0.0707
Echinococcus multilocularis Zinc finger, DBF type 0.0024 0.0008 0.0005
Giardia lamblia Cathepsin B precursor 0.0051 0.0113 0.0495
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0051 0.0116 0.0113
Plasmodium falciparum thioredoxin reductase 0.0051 0.0116 0.0798
Echinococcus granulosus intermediate filament protein 0.0026 0.0018 0.0015
Schistosoma mansoni hepatitis B virus X associated protein hbxa 0.0024 0.0008 0.0005
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.025 0.0897 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0061 0.0154 0.02
Onchocerca volvulus Alhambra homolog 0.0089 0.0263 0.0547
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0265 0.0959 0.2036
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0059 0.0147 0.0313
Trypanosoma cruzi heat shock protein, putative 0.0065 0.0168 0.0565
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0026 0.0017 0.0014
Echinococcus multilocularis jumonji domain containing 1A 0.0029 0.0027 0.0023
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0029 0.0027 0.0024
Trichomonas vaginalis glucosylceramidase, putative 0.0524 0.1976 0.4195
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.035 0.0744
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0061 0.0154 0.02
Schistosoma mansoni hypothetical protein 0.0024 0.0008 0.0005
Leishmania major cysteine peptidase A (CPA) 0.0111 0.035 0.3616
Loa Loa (eye worm) thioredoxin reductase 0.0148 0.0498 0.0661
Loa Loa (eye worm) hypothetical protein 0.0032 0.0041 0.0048
Brugia malayi Steroid receptor seven-up type 2 0.0061 0.0154 0.02
Echinococcus multilocularis neuropeptide s receptor 0.0466 0.1748 0.1746
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0082 0.0235 0.0309
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0027 0.0024
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0313
Echinococcus granulosus histone acetyltransferase myst4 0.0024 0.0008 0.0005
Plasmodium vivax vivapain-2 0.0111 0.035 0.2522
Leishmania major cathepsin L-like protease 0.0157 0.0532 0.552
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0029
Echinococcus granulosus neuropeptide receptor A26 0.0466 0.1748 0.1746
Schistosoma mansoni tyrosine kinase 0.0615 0.2338 0.2336
Echinococcus granulosus PHD and RING finger domain containing protein 1 0.0024 0.0008 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0113 0.024
Loa Loa (eye worm) matrix metalloproteinase 0.0036 0.0054 0.0065
Trypanosoma brucei heat shock protein 84, putative 0.0065 0.0168 0.1687
Giardia lamblia Cathepsin L precursor 0.0051 0.0113 0.0495
Entamoeba histolytica cysteine protease, putative 0.0103 0.0319 0.3517
Schistosoma mansoni tar DNA-binding protein 0.0252 0.0907 0.0904
Entamoeba histolytica cysteine protease, putative 0.0103 0.0319 0.3517
Brugia malayi Nuclear hormone receptor E75 0.0029 0.0027 0.0029
Echinococcus multilocularis PHD and RING finger domain containing protein 1 0.0024 0.0008 0.0005
Echinococcus multilocularis protein kinase c iota type 0.0094 0.0286 0.0283
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0103 0.0319 0.1095
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.0041 0.0048
Loa Loa (eye worm) F/Y-rich family protein 0.0024 0.0008 0.0003
Schistosoma mansoni hypothetical protein 0.0089 0.0263 0.026
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0029
Plasmodium falciparum serine repeat antigen 2 0.0051 0.0113 0.0776
Echinococcus granulosus cathepsin L 0.0051 0.0113 0.011
Entamoeba histolytica transcription factor BTF3, putative 0.0071 0.0192 0.2098
Onchocerca volvulus Glucosylceramidase homolog 0.0524 0.1976 0.4188
Schistosoma mansoni bromodomain containing protein 0.0465 0.1745 0.1742
Plasmodium vivax serine-repeat antigen (SERA) 0.0051 0.0113 0.0776
Plasmodium vivax vivapain-1 0.0103 0.0319 0.2291
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0051 0.0113 0.0776
Toxoplasma gondii preprocathepsin c precursor, putative 0.0051 0.0113 0.0776
Plasmodium falciparum serine repeat antigen 9 0.0051 0.0113 0.0776
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0051 0.0116 0.0381
Onchocerca volvulus 0.0168 0.0577 0.1214
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0033 0.0044 0.0153
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0061 0.0154 0.0151
Echinococcus granulosus cysteine protease 0.0103 0.0319 0.0316
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0157 0.0532 0.5509
Loa Loa (eye worm) hypothetical protein 0.0029 0.0029 0.0032
Brugia malayi cathepsin L-like precursor 0.0059 0.0145 0.0187
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0029 0.0029 0.0026
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0163 0.0555 0.0738
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0129 0.0423 0.042
Entamoeba histolytica hypothetical protein 0.0035 0.0051 0.0512
Onchocerca volvulus 0.0051 0.0113 0.0229
Loa Loa (eye worm) hypothetical protein 0.0036 0.0054 0.0065
Echinococcus multilocularis Immunoglobulin 0.0029 0.0029 0.0026
Giardia lamblia Cathepsin B precursor 0.0051 0.0113 0.0495
Echinococcus multilocularis lysine specific demethylase 5B 0.0024 0.0008 0.0005
Echinococcus granulosus endoplasmin 0.0091 0.0273 0.027
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.004 0.0073 0.0229
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0111 0.035 0.0744
Echinococcus granulosus lysine specific demethylase 6a 0.0029 0.0027 0.0023
Brugia malayi Hemopexin family protein 0.005 0.0113 0.0144
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0029
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0657 0.25 1
Echinococcus granulosus chromobox protein 1 0.0069 0.0187 0.0184
Loa Loa (eye worm) hypothetical protein 0.0441 0.1652 0.2212
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0043 0.0085 0.0317
Loa Loa (eye worm) hypothetical protein 0.0032 0.0041 0.0048
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0157 0.0532 0.5509
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0142 0.0473 0.1004
Trypanosoma cruzi cysteine peptidase, putative 0.0157 0.0532 0.1845
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0029 0.0027 0.0023
Brugia malayi nuclear receptor RXR 0.0032 0.0041 0.0048
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.004 0.0073 0.0155
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0035 0.0053 0.0049
Onchocerca volvulus Cathepsin L homolog 0.0051 0.0113 0.0229
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0059 0.0147 0.0144
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0376 0.1394 0.5565
Brugia malayi Thioredoxin reductase 0.0148 0.0498 0.0661
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0051 0.0116 0.0381
Onchocerca volvulus 0.0024 0.0008 0.0005
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0059 0.0147 0.0144
Onchocerca volvulus 0.0111 0.035 0.0733
Loa Loa (eye worm) hypothetical protein 0.0152 0.0512 0.0681
Schistosoma mansoni jumonji domain containing protein 0.0029 0.0027 0.0023
Echinococcus multilocularis roundabout 2 0.0046 0.0096 0.0093
Loa Loa (eye worm) hypothetical protein 0.0032 0.0041 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0067 0.0142
Schistosoma mansoni endoplasmin 0.0097 0.0297 0.0294
Brugia malayi Cathepsin L-like precursor 0.0111 0.035 0.0463
Loa Loa (eye worm) hypothetical protein 0.005 0.0111 0.0141
Schistosoma mansoni tyrosine kinase 0.0808 0.3094 0.3092
Brugia malayi acetyltransferase, GNAT family protein 0.0163 0.0557 0.074
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0051 0.0113 0.011
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0061 0.0154 0.0151
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0032 0.0041 0.0038
Loa Loa (eye worm) hypothetical protein 0.0051 0.0113 0.0145
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0082 0.0235 0.0232
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0069 0.0452
Schistosoma mansoni sex comb on midleg homolog 0.0143 0.0477 0.0474
Brugia malayi PHD-finger family protein 0.0024 0.0008 0.0003
Brugia malayi Papain family cysteine protease containing protein 0.0051 0.0113 0.0145
Plasmodium vivax hypothetical protein, conserved 0.0089 0.0263 0.1879
Echinococcus granulosus neuroglian 0.0037 0.0058 0.0055
Schistosoma mansoni tyrosine kinase 0.0034 0.0047 0.0044
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0082 0.0235 0.0232
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0157 0.0532 0.5509
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0113 0.024
Schistosoma mansoni myst histone acetyltransferase 0.0024 0.0008 0.0005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0157 0.0532 0.5509
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0157 0.0532 0.5509
Entamoeba histolytica cysteine proteinase, putative 0.0103 0.0319 0.3517
Entamoeba histolytica cysteine proteinase 1, putative 0.0103 0.0319 0.3517
Trichomonas vaginalis glucosylceramidase, putative 0.0524 0.1976 0.4195
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0338 0.1245 0.497
Plasmodium falciparum cysteine proteinase falcipain 1 0.0103 0.0319 0.2291
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.035 0.0744
Brugia malayi Calcitonin receptor-like protein seb-1 0.0258 0.0929 0.1241
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0745 0.2848 0.2846
Entamoeba histolytica cysteine proteinase 2 0.0103 0.0319 0.3517
Plasmodium falciparum heat shock protein 90, putative 0.0369 0.1365 1
Brugia malayi Latrophilin receptor protein 2 0.0082 0.0235 0.0309
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.035 0.0744
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0051 0.0116 0.0113
Brugia malayi hypothetical protein 0.0049 0.0105 0.0134
Loa Loa (eye worm) hypothetical protein 0.0143 0.0477 0.0633
Schistosoma mansoni hypothetical protein 0.0082 0.0235 0.0232
Plasmodium vivax serine-repeat antigen (SERA) 0.0051 0.0113 0.0776
Brugia malayi hypothetical protein 0.0461 0.1731 0.2317
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.0203 0.0686
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0059 0.0147 0.0313
Leishmania major cathepsin L-like protease 0.0157 0.0532 0.552
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0051 0.0113 0.0776
Entamoeba histolytica cysteine protease, putative 0.0103 0.0319 0.3517
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0119 0.0252
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0113 0.024
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0061 0.0154 0.0151
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0059 0.0147 0.0491
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0192 0.0408
Trypanosoma cruzi cysteine proteinase, putative 0.0103 0.0319 0.1095
Echinococcus granulosus lysine specific demethylase 5B 0.0024 0.0008 0.0005
Echinococcus multilocularis nuclear receptor nhr 48 0.0029 0.0027 0.0024
Brugia malayi hypothetical protein 0.0029 0.0027 0.0029
Leishmania major cathepsin L-like protease 0.0111 0.035 0.3616
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0103 0.0319 0.0316
Entamoeba histolytica cysteine protease, putative 0.0103 0.0319 0.3517
Brugia malayi conserved hypotetical protein 0.0029 0.0027 0.0029
Loa Loa (eye worm) hypothetical protein 0.0061 0.0154 0.02
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0051 0.0113 0.0776
Trypanosoma cruzi ISWI complex protein 0.0109 0.0343 0.1181
Entamoeba histolytica cysteine proteinase, putative 0.0103 0.0319 0.3517
Trichomonas vaginalis bromodomain-containing protein, putative 0.006 0.015 0.0318
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0029 0.0027 0.0137
Echinococcus granulosus microtubule associated protein 2 0.1364 0.5286 0.5284
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0489 0.1841 0.2465
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0059 0.0147 0.0313
Mycobacterium ulcerans hydrolase 0.0043 0.0085 0.0317
Trypanosoma cruzi cysteine peptidase, putative 0.0103 0.0319 0.1095
Plasmodium vivax SET domain containing protein 0.003 0.0032 0.0178
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0171 0.0587 0.0584
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0033 0.0044 0.0153
Echinococcus granulosus mixed lineage leukemia protein mll 0.005 0.0112 0.0109
Onchocerca volvulus 0.005 0.0111 0.0223
Brugia malayi jmjC domain containing protein 0.0029 0.0027 0.0028
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0026 0.0017 0.0014
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0059 0.0147 0.0313
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.029 0.1057 0.1054
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.0119 0.0253
Trichomonas vaginalis inhibitor of growth, putative 0.0024 0.0008 0.0017
Onchocerca volvulus Matrilysin homolog 0.0036 0.0054 0.0103
Loa Loa (eye worm) hypothetical protein 0.025 0.0897 0.1197
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.0119 0.0253
Loa Loa (eye worm) hypothetical protein 0.0082 0.0235 0.0309
Schistosoma mansoni inositol monophosphatase 0.0073 0.0203 0.02
Trichomonas vaginalis glucosylceramidase, putative 0.0798 0.3057 0.649
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0142 0.0473 0.1004
Echinococcus granulosus heat shock protein 90 0.0097 0.0297 0.0294
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0052 0.0121 0.0117
Leishmania major heat shock protein 83-1 0.0097 0.0297 0.3056
Echinococcus multilocularis polycomb protein SCMH1 0.0143 0.0477 0.0474
Brugia malayi PHD-finger family protein 0.0089 0.0263 0.0346
Loa Loa (eye worm) PHD-finger family protein 0.0024 0.0008 0.0003
Onchocerca volvulus 0.0024 0.0008 0.0005
Plasmodium vivax heat shock protein 86, putative 0.0097 0.0297 0.2129
Echinococcus granulosus defective proboscis extension response 0.0029 0.0029 0.0026
Schistosoma mansoni zinc finger protein 0.0029 0.0027 0.0024
Echinococcus granulosus cathepsin l cysteine peptidase 0.0111 0.035 0.0347
Echinococcus granulosus histone acetyltransferase myst3 0.0024 0.0008 0.0005
Schistosoma mansoni cell adhesion molecule 0.0039 0.0067 0.0063
Onchocerca volvulus 0.0143 0.0477 0.1001
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0258 0.0929 0.1241
Toxoplasma gondii cathepsin CPC1 0.0051 0.0113 0.0776
Echinococcus granulosus cathepsin l1 0.0111 0.035 0.0347
Echinococcus multilocularis remodeling and spacing factor 1 0.0024 0.0008 0.0005
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0051 0.0116 0.0444
Schistosoma mansoni tyrosine kinase 0.1014 0.3908 0.3906
Leishmania major heat shock protein 83-1 0.0097 0.0297 0.3056
Brugia malayi Cathepsin L-like precursor 0.0052 0.012 0.0153
Trichomonas vaginalis set domain proteins, putative 0.1218 0.4711 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0157 0.0532 0.0529
Loa Loa (eye worm) hypothetical protein 0.0278 0.1011 0.135
Schistosoma mansoni zinc finger protein 0.0024 0.0008 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0119 0.0252
Brugia malayi nuclear receptor NHR-88 0.0061 0.0154 0.02
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0051 0.0116 0.0381
Entamoeba histolytica cysteine protease, putative 0.0103 0.0319 0.3517
Brugia malayi Endoplasmin precursor 0.0097 0.0297 0.0392
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0031 0.0038 0.0034
Brugia malayi hypothetical protein 0.0441 0.1652 0.2212
Echinococcus granulosus protein tyrosine kinase 0.0808 0.3094 0.3092
Loa Loa (eye worm) hypothetical protein 0.0052 0.012 0.0153
Trichomonas vaginalis glucosylceramidase, putative 0.0524 0.1976 0.4195
Entamoeba histolytica cysteine proteinase, putative 0.0059 0.0145 0.1562
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0051 0.0113 0.011
Echinococcus granulosus polycomb protein SCMH1 0.0143 0.0477 0.0474
Trypanosoma brucei heat shock protein 90, putative 0.0097 0.0297 0.3038
Loa Loa (eye worm) hypothetical protein 0.0051 0.0113 0.0145
Echinococcus multilocularis JmjC domain containing protein 4 0.0029 0.0027 0.0023
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0065 0.0168 0.0346
Echinococcus multilocularis heat shock protein 0.0097 0.0297 0.0294
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0313
Brugia malayi Hsp90 protein 0.0065 0.0168 0.0219
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0061 0.0154 0.02
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0051 0.0116 0.0381
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0657 0.25 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0029 0.0032
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0052 0.0119 0.0253
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0051 0.0116 0.0798
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0113 0.024
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0051 0.0116 0.0381
Brugia malayi MH2 domain containing protein 0.0241 0.0862 0.115
Schistosoma mansoni zinc finger protein 0.0024 0.0008 0.0005
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0078 0.0167
Giardia lamblia Cathepsin L precursor 0.0051 0.0113 0.0495
Entamoeba histolytica cysteine proteinase, putative 0.0103 0.0319 0.3517
Onchocerca volvulus 0.0024 0.0008 0.0005
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0067 0.0131
Loa Loa (eye worm) glutathione reductase 0.0148 0.0498 0.0661
Echinococcus granulosus twitchin 0.0037 0.0059 0.0056
Trypanosoma brucei heat shock protein, putative 0.0097 0.0297 0.3038
Plasmodium vivax histone acetyltransferase GCN5, putative 0.006 0.015 0.1045
Schistosoma mansoni hypothetical protein 0.0872 0.335 0.3348
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0066 0.0173 0.067
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0111 0.035 0.0347
Schistosoma mansoni methyl-cpg binding protein mbd 0.0122 0.0393 0.039
Loa Loa (eye worm) hypothetical protein 0.0504 0.1899 0.2544
Loa Loa (eye worm) TK/FAK protein kinase 0.0817 0.3131 0.4199
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0061 0.0154 0.02
Brugia malayi Inositol-1 0.0073 0.0203 0.0265
Entamoeba histolytica cysteine proteinase, putative 0.0103 0.0319 0.3517
Brugia malayi ecdysteroid receptor 0.0061 0.0154 0.02
Leishmania major heat shock protein 83-1 0.0097 0.0297 0.3056
Entamoeba histolytica hypothetical protein 0.0073 0.0203 0.2213
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0028
Brugia malayi nuclear hormone receptor family member nhr-6 0.0029 0.0027 0.0029
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.006 0.015 0.0318
Toxoplasma gondii PHD-finger domain-containing protein 0.0089 0.0263 0.1879
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0567 0.2146 0.2144
Loa Loa (eye worm) jmjC domain-containing protein 0.0029 0.0027 0.0028
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0111 0.035 0.0744
Echinococcus granulosus thioredoxin glutathione reductase 0.0148 0.0498 0.0495
Echinococcus multilocularis phd:f box containing protein 0.0029 0.0027 0.0023
Plasmodium falciparum glutathione reductase 0.0148 0.0498 0.3607
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0152 0.0149
Entamoeba histolytica cysteine protease, putative 0.0103 0.0319 0.3517
Schistosoma mansoni hypothetical protein 0.1732 0.6737 0.6736
Loa Loa (eye worm) MH2 domain-containing protein 0.0241 0.0862 0.115
Echinococcus multilocularis chromobox protein 1 0.0069 0.0187 0.0184
Onchocerca volvulus 0.005 0.0113 0.0228
Entamoeba histolytica cysteine protease, putative 0.0051 0.0113 0.121
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0008 0.0017
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0111 0.035 0.0744
Schistosoma mansoni thyroid hormone receptor 0.0061 0.0154 0.0151
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0051 0.0116 0.1138
Plasmodium vivax glutathione reductase, putative 0.0148 0.0498 0.3607
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0051 0.0116 0.1161
Schistosoma mansoni requim req/dpf2 0.0024 0.0008 0.0005
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0051 0.0113 0.0495
Trichomonas vaginalis heat shock protein, putative 0.0097 0.0297 0.063
Trichomonas vaginalis glucosylceramidase, putative 0.0798 0.3057 0.649
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0313
Echinococcus multilocularis heat shock protein 90 0.0083 0.0242 0.0238
Echinococcus granulosus lamin dm0 0.0026 0.0018 0.0015
Loa Loa (eye worm) RNA binding protein 0.0252 0.0907 0.1211
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.0203 0.2049
Schistosoma mansoni PHD zinc finger protein XAP135-related 0.0024 0.0008 0.0005
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0092 0.0277 0.0365
Loa Loa (eye worm) hypothetical protein 0.0051 0.0113 0.0145
Loa Loa (eye worm) hypothetical protein 0.0318 0.1166 0.1558
Echinococcus multilocularis jumonji domain containing protein 0.0123 0.04 0.0397
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0028
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0024 0.0008 0.0005
Giardia lamblia Hypothetical protein 0.0051 0.0113 0.0495
Leishmania major hypothetical protein, conserved 0.0109 0.0343 0.3544
Schistosoma mansoni SET domain protein 0.0033 0.0046 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0008 0.0017
Echinococcus granulosus heat shock protein 90 0.0083 0.0242 0.0238
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0111 0.035 0.2522
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0051 0.0116 0.0798
Loa Loa (eye worm) hypothetical protein 0.0039 0.0067 0.0083
Toxoplasma gondii thioredoxin reductase 0.0148 0.0498 0.3607
Schistosoma mansoni hypothetical protein 0.0109 0.0343 0.034
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0171 0.0587 0.0584
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0113 0.024
Brugia malayi PHD-finger family protein 0.0191 0.0668 0.089
Brugia malayi nuclear hormone receptor 0.0029 0.0027 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0113 0.024
Brugia malayi hypothetical protein 0.0075 0.0211 0.0276
Schistosoma mansoni heat shock protein 0.0097 0.0297 0.0294
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0142 0.0473 0.0628
Brugia malayi Protein kinase domain containing protein 0.0817 0.3131 0.4199
Schistosoma mansoni nuclear receptor 0.0029 0.0027 0.0024
Brugia malayi hypothetical protein 0.0024 0.0008 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0051 0.0113 0.024
Plasmodium falciparum serine repeat antigen 5 0.0051 0.0113 0.0776
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0051 0.0113 0.024
Loa Loa (eye worm) hypothetical protein 0.0151 0.0508 0.0675
Brugia malayi TAR-binding protein 0.0252 0.0907 0.1211
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0029 0.0027 0.0024
Loa Loa (eye worm) DR-78 0.0029 0.0027 0.0029
Schistosoma mansoni steroid hormone receptor ad4bp 0.0061 0.0154 0.0151
Echinococcus granulosus chromobox protein 1 0.0069 0.0187 0.0184
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0152 0.0588
Echinococcus multilocularis PHD finger protein rhinoceros 0.0089 0.0263 0.026
Echinococcus granulosus cathepsin L cysteine protease 0.0103 0.0319 0.0316
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0008 0.0017
Brugia malayi mbt repeat family protein 0.0143 0.0477 0.0633
Echinococcus multilocularis phd finger protein 10 0.0024 0.0008 0.0005
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0059 0.0147 0.0144
Loa Loa (eye worm) hypothetical protein 0.0258 0.0929 0.1241
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0142 0.0473 0.047
Echinococcus granulosus muscleblind protein 0.0151 0.0508 0.0505
Giardia lamblia Cathepsin L precursor 0.0051 0.0113 0.0495
Loa Loa (eye worm) hypothetical protein 0.0029 0.0029 0.0032
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0113 0.024
Schistosoma mansoni hypothetical protein 0.2561 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0192 0.0408
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.035 0.0744
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0152 0.0149
Loa Loa (eye worm) hypothetical protein 0.0024 0.0008 0.0003
Giardia lamblia Cathepsin L precursor 0.0051 0.0113 0.0495
Schistosoma mansoni cathepsin S (C01 family) 0.0051 0.0113 0.011
Loa Loa (eye worm) hypothetical protein 0.0061 0.0154 0.02
Mycobacterium leprae PROBABLE HYDROLASE 0.0043 0.0085 0.0317
Treponema pallidum fructose-bisphosphate aldolase 0.0142 0.0473 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0061 0.0154 0.0151
Entamoeba histolytica cysteine protease, putative 0.0103 0.0319 0.3517
Echinococcus multilocularis zinc finger protein 0.0153 0.0518 0.0515
Loa Loa (eye worm) hypothetical protein 0.0273 0.0991 0.1324
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0061 0.0155 0.0152
Giardia lamblia Cathepsin B precursor 0.0265 0.0959 1
Loa Loa (eye worm) heat shock protein 90 0.0097 0.0297 0.0392
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0798 0.3057 0.4099
Echinococcus multilocularis microtubule associated protein 2 0.1364 0.5286 0.5284
Echinococcus multilocularis tumor protein p63 0.0341 0.1257 0.1254
Brugia malayi fibroinase precursor 0.0051 0.0113 0.0145
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0074 0.0158
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0439 0.1644 0.1642
Schistosoma mansoni jumonji domain containing protein 0.0231 0.0822 0.0819
Echinococcus multilocularis mixed lineage leukemia protein mll 0.005 0.0112 0.0109
Echinococcus multilocularis muscleblind protein 0.0151 0.0508 0.0505
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0051 0.0113 0.0776
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0142 0.0473 0.047
Echinococcus granulosus Zinc finger DBF type 0.0024 0.0008 0.0005
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0035 0.0053 0.0049
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0061 0.0154 0.0316
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0567 0.2146 0.2144
Brugia malayi nuclear receptor NHR-88 0.0029 0.0027 0.0029
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0061 0.0154 0.02
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0745 0.2848 0.2846
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0376 0.1394 0.5565
Trichomonas vaginalis glucosylceramidase, putative 0.0524 0.1976 0.4195
Giardia lamblia Encystation-specific protease 0.0051 0.0113 0.0495
Loa Loa (eye worm) hypothetical protein 0.0052 0.012 0.0153
Echinococcus multilocularis lamin 0.0026 0.0018 0.0015
Plasmodium vivax unspecified product 0.0103 0.0319 0.2291
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0073 0.0203 0.2214
Giardia lamblia Fructose-bisphosphate aldolase 0.0142 0.0473 0.4539
Plasmodium falciparum ataxin-2 like protein, putative 0.0075 0.0211 0.1493
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0111 0.035 0.0347
Loa Loa (eye worm) hypothetical protein 0.0059 0.0145 0.0187
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0142 0.0473 0.1004
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.005 0.0112 0.0109
Echinococcus multilocularis PHD finger protein 14 0.0024 0.0008 0.0005
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0111 0.035 0.0463
Brugia malayi Bromodomain containing protein 0.0548 0.2074 0.2778
Leishmania major cathepsin L-like protease 0.0111 0.035 0.3616
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0061 0.0154 0.0151
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0029 0.0027 0.0137
Toxoplasma gondii heat shock protein 90, putative 0.0097 0.0297 0.2129
Onchocerca volvulus Cathepsin F homolog 0.0111 0.035 0.0733
Schistosoma mansoni bromodomain containing protein 0.0044 0.0088 0.0085
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0034 0.0047 0.0044
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0142 0.0473 0.047
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0142 0.0473 0.5247
Brugia malayi Papain family cysteine protease containing protein 0.0111 0.035 0.0463
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0051 0.0113 0.024
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0061 0.0154 0.0151
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0051 0.0113 0.011
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0051 0.0113 0.121
Echinococcus granulosus roundabout 2 0.0046 0.0096 0.0093
Onchocerca volvulus 0.0026 0.0018 0.0027
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0059 0.0147 0.0491
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.0119 0.0253
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.025 0.0897 1
Plasmodium falciparum serine repeat antigen 7 0.0051 0.0113 0.0776
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0029
Giardia lamblia NADH oxidase lateral transfer candidate 0.0051 0.0116 0.0527
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0051 0.0116 0.0113
Loa Loa (eye worm) hypothetical protein 0.0024 0.0008 0.0003
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0082 0.0235 0.0232
Brugia malayi Hypothetical C28H8.9 in chromosome III 0.0024 0.0008 0.0003
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0066 0.0173 0.067
Onchocerca volvulus Protein ultraspiracle homolog 0.0061 0.0154 0.0316
Trichomonas vaginalis glutathione reductase, putative 0.0051 0.0116 0.0247
Trypanosoma cruzi heat shock protein 85, putative 0.0083 0.0242 0.0823
Loa Loa (eye worm) hypothetical protein 0.0089 0.0263 0.0346
Schistosoma mansoni myst-related protein 0.0035 0.0051 0.0048
Leishmania major heat shock protein 83-1 0.0097 0.0297 0.3056
Entamoeba histolytica cysteine protease, putative 0.0103 0.0319 0.3517
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0051 0.0113 0.0145
Echinococcus multilocularis uro adherence factor A 0.0024 0.0008 0.0005
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0051 0.0113 0.0776
Onchocerca volvulus 0.0111 0.035 0.0733
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.035 0.0744
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0008 0.0017
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0051 0.0116 0.1161
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0026 0.0017 0.0036
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.035 0.0744
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0051 0.0116 0.1161
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.0119 0.0253
Loa Loa (eye worm) jmjC domain-containing protein 0.0029 0.0027 0.0028
Onchocerca volvulus Tyrosine kinase homolog 0.0458 0.1717 0.3638
Leishmania major heat shock protein 83-1 0.0097 0.0297 0.3056
Trypanosoma brucei cysteine peptidase C (CPC) 0.0265 0.0959 1
Schistosoma mansoni sex comb on midleg homolog 0.0143 0.0477 0.0474
Plasmodium falciparum endoplasmin, putative 0.0071 0.0192 0.1355
Brugia malayi cathepsin B-like cysteine proteinase 0.0745 0.2848 0.3819
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0338 0.1245 0.497
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0258 0.0929 0.1241
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0313
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0029 0.0028 0.0211
Schistosoma mansoni endoplasmin 0.0097 0.0297 0.0294
Giardia lamblia Cathepsin B precursor 0.0265 0.0959 1
Loa Loa (eye worm) TK/ROR protein kinase 0.0024 0.0009 0.0005
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0059 0.0147 0.1465
Loa Loa (eye worm) hypothetical protein 0.0026 0.0016 0.0014
Trypanosoma brucei heat shock protein, putative 0.0097 0.0297 0.3038
Brugia malayi cathepsin F-like cysteine proteinase 0.0051 0.0113 0.0145
Brugia malayi PHD-finger family protein 0.0024 0.0008 0.0003
Brugia malayi Bromodomain containing protein 0.0109 0.0343 0.0454
Entamoeba histolytica cysteine protease, putative 0.0103 0.0319 0.3517
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0091 0.0273 0.1074
Leishmania major heat shock protein 83-1 0.0097 0.0297 0.3056
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0111 0.0107
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0142 0.0473 0.5247
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0157 0.0532 0.5509
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0252 0.0907 0.1211
Loa Loa (eye worm) hypothetical protein 0.0024 0.0008 0.0003
Schistosoma mansoni cpg binding protein 0.0204 0.0716 0.0713
Onchocerca volvulus Matrix metalloproteinase homolog 0.0079 0.0225 0.0466
Trypanosoma cruzi heat shock protein 90, putative 0.0041 0.0074 0.0234
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0051 0.0113 0.0776
Brugia malayi Cathepsin L-like cysteine proteinase 0.0059 0.0145 0.0187
Echinococcus multilocularis transcription factor btf3 0.0071 0.0192 0.0189
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0192 0.0408
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0078 0.0155
Schistosoma mansoni cpg binding protein 0.0204 0.0716 0.0713
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0091 0.0273 0.1074
Loa Loa (eye worm) hypothetical protein 0.0061 0.0154 0.02
Plasmodium falciparum phd finger protein, putative 0.0089 0.0263 0.1879
Echinococcus multilocularis tar DNA binding protein 0.0252 0.0907 0.0904
Echinococcus granulosus histone lysine methyltransferase setb 0.0278 0.1011 0.1008
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0061 0.0154 0.0151
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.035 0.0744
Onchocerca volvulus 0.0441 0.1652 0.35
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0745 0.2848 0.2846
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0079 0.0226 0.0223
Trichomonas vaginalis heat shock protein, putative 0.0091 0.0273 0.058
Loa Loa (eye worm) hypothetical protein 0.0053 0.0122 0.0157
Echinococcus granulosus histone acetyltransferase MYST2 0.0163 0.0555 0.0552
Trypanosoma cruzi cruzipain precursor, putative 0.0052 0.012 0.0393
Echinococcus multilocularis heat shock protein 90 0.0097 0.0297 0.0294
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0025 0.0011 0.0037
Brugia malayi Matrixin family protein 0.0036 0.0054 0.0065
Schistosoma mansoni intermediate filament proteins 0.0026 0.0018 0.0015
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0029 0.0027 0.0046
Leishmania major cathepsin L-like protease 0.0111 0.035 0.3616
Plasmodium vivax vivapain-3 0.0103 0.0319 0.2291
Echinococcus granulosus tumor protein p63 0.0341 0.1257 0.1254
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0038 0.0062 0.0077
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0051 0.0116 0.0444
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0051 0.0116 0.0381
Brugia malayi Furin-like cysteine rich region family protein 0.1913 0.745 1
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0051 0.0113 0.0145
Brugia malayi cathepsin Z-like cysteine proteinase 0.0051 0.0113 0.0145
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0313
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0103 0.0319 0.327
Brugia malayi PHD-finger family protein 0.0053 0.0122 0.0157
Plasmodium falciparum serine repeat antigen 3 0.0051 0.0113 0.0776
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0148 0.0498 0.1973
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0065 0.0168 0.0165
Onchocerca volvulus 0.003 0.0034 0.006
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0032 0.0041 0.0038
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0163 0.0557 0.0554
Brugia malayi RNA recognition motif domain containing protein 0.0252 0.0907 0.1211
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0051 0.0113 0.0776
Entamoeba histolytica cysteine protease, putative 0.0051 0.0113 0.121
Brugia malayi nuclear hormone receptor 0.0061 0.0154 0.02
Trypanosoma cruzi Heat shock protein 83, putative 0.0097 0.0297 0.1017
Echinococcus multilocularis neuroglian 0.0037 0.0058 0.0055
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0061 0.0154 0.0151
Brugia malayi glutathione reductase 0.0148 0.0498 0.0661
Schistosoma mansoni hypothetical protein 0.0176 0.0608 0.0605
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0051 0.0113 0.0776
Loa Loa (eye worm) fibroinase 0.0111 0.035 0.0463
Loa Loa (eye worm) steroid hormone receptor 0.0061 0.0154 0.02
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0051 0.0113 0.121
Schistosoma mansoni lozenge 0.0055 0.0132 0.0129
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0051 0.0113 0.024
Entamoeba histolytica heat shock protein 90, putative 0.0097 0.0297 0.327
Loa Loa (eye worm) matrixin family protein 0.0079 0.0225 0.0295
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.0203 0.02
Schistosoma mansoni chromobox protein 0.0069 0.0187 0.0184
Plasmodium vivax hypothetical protein, conserved 0.004 0.0071 0.0466
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0157 0.0532 0.5509
Brugia malayi steroid hormone receptor 0.0061 0.0154 0.02
Entamoeba histolytica hypothetical protein 0.0071 0.0192 0.2098
Loa Loa (eye worm) hypothetical protein 0.0024 0.0008 0.0003
Plasmodium vivax ataxin-2 like protein, putative 0.0075 0.0211 0.1493
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1071 0.413 0.5541
Plasmodium vivax unspecified product 0.0051 0.0113 0.0776
Trypanosoma brucei heat shock protein 90, putative 0.0097 0.0297 0.3038
Giardia lamblia Heat shock protein HSP 90-alpha 0.0097 0.0297 0.2558
Loa Loa (eye worm) runx1 0.0055 0.0132 0.017
Leishmania major heat shock protein 83-1 0.0097 0.0297 0.3056
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.035 0.0744
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0059 0.0147 0.0313
Loa Loa (eye worm) nuclear hormone receptor 0.0029 0.0027 0.0029
Entamoeba histolytica hypothetical protein 0.0073 0.0203 0.2213
Mycobacterium tuberculosis Probable oxidoreductase 0.0376 0.1394 0.5565
Onchocerca volvulus Cathepsin L homolog 0.0111 0.035 0.0733
Echinococcus granulosus transcription factor btf3 0.0071 0.0192 0.0189
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0111 0.035 0.0744
Trypanosoma brucei transcription factor BTF3, putative 0.0071 0.0192 0.194
Brugia malayi Cathepsin L-like precursor 0.0111 0.035 0.0463
Loa Loa (eye worm) endoplasmin 0.0097 0.0297 0.0392
Trichomonas vaginalis heat shock protein, putative 0.0091 0.0273 0.058
Loa Loa (eye worm) hypothetical protein 0.0061 0.0154 0.02
Schistosoma mansoni cathepsin B (C01 family) 0.0051 0.0113 0.011
Brugia malayi Protein kinase domain containing protein 0.0615 0.2338 0.3133
Plasmodium falciparum basic transcription factor 3b, putative 0.0071 0.0192 0.1359
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0111 0.035 0.0744
Loa Loa (eye worm) hypothetical protein 0.0029 0.0029 0.0032
Trypanosoma brucei heat shock protein, putative 0.0097 0.0297 0.3038
Giardia lamblia Cysteine protease 0.0051 0.0113 0.0495
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0022 0.0047
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0061 0.0154 0.0151
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0157 0.0532 0.0529
Schistosoma mansoni hypothetical protein 0.005 0.0113 0.0109
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0387 0.1438 0.1435
Trichomonas vaginalis glucosylceramidase, putative 0.0524 0.1976 0.4195
Schistosoma mansoni cathepsin F (C01 family) 0.0059 0.0145 0.0141
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0008 0.0017
Trypanosoma cruzi PAB1-binding protein , putative 0.0075 0.0211 0.0713
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0059 0.0147 0.0313
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0256 0.0923 0.092
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0051 0.0113 0.024
Brugia malayi Pre-SET motif family protein 0.1071 0.413 0.5541
Echinococcus multilocularis Protein lozenge 0.0055 0.0132 0.0129
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0008 0.0017
Trypanosoma brucei trypanothione reductase 0.0148 0.0498 0.5148
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0051 0.0113 0.0776
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0051 0.0113 0.0776
Toxoplasma gondii PHD-finger domain-containing protein 0.0089 0.0263 0.1879
Echinococcus granulosus geminin 0.1732 0.6737 0.6736
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0147 0.0494 0.0491
Trypanosoma cruzi ISWI complex protein 0.0109 0.0343 0.1181
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0082 0.0235 0.0232
Brugia malayi Cathepsin L-like precursor 0.0111 0.035 0.0463
Schistosoma mansoni nuclear receptor nhr-48 0.0029 0.0027 0.0024
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0376 0.1394 0.5565
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0051 0.0113 0.011
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0615 0.2338 0.2336
Schistosoma mansoni tar DNA-binding protein 0.0252 0.0907 0.0904
Giardia lamblia Heat shock protein HSP 90-alpha 0.0083 0.0242 0.1936
Schistosoma mansoni hypothetical protein 0.0082 0.0235 0.0232
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0147 0.0313
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0059 0.0145 0.0307
Brugia malayi Nuclear hormone receptor E75 0.0029 0.0027 0.0029
Leishmania major heat shock protein, putative 0.0065 0.0168 0.1708
Leishmania major heat shock protein 83-1 0.0097 0.0297 0.3056
Echinococcus granulosus histone acetyltransferase KAT2B 0.0142 0.0474 0.0471
Echinococcus multilocularis endoplasmin 0.0091 0.0273 0.027
Schistosoma mansoni nuclear receptor 0.0029 0.0027 0.0024
Plasmodium vivax heat shock protein, putative 0.0369 0.1365 1
Loa Loa (eye worm) hypothetical protein 0.0059 0.0145 0.0187
Onchocerca volvulus 0.1218 0.4711 1
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0265 0.0959 0.3349
Echinococcus multilocularis lysine specific demethylase 5A 0.0107 0.0336 0.0333
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0024 0.0009 0.0006
Loa Loa (eye worm) hypothetical protein 0.0032 0.0041 0.0048
Toxoplasma gondii hypothetical protein 0.0052 0.0119 0.0815
Trypanosoma cruzi heat shock protein 90, putative 0.0083 0.0242 0.0823
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0051 0.0113 0.0776
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0103 0.0319 0.0316
Leishmania major hypothetical protein, conserved 0.0029 0.0027 0.0222
Brugia malayi heat shock protein 90 0.0097 0.0297 0.0392
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0061 0.0154 0.0151
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0059 0.0147 0.0491
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0051 0.0116 0.0798
Echinococcus granulosus serine protein kinase ATM 0.0025 0.0011 0.0008
Brugia malayi Papain family cysteine protease containing protein 0.0051 0.0113 0.0145
Trichomonas vaginalis glucosylceramidase, putative 0.0524 0.1976 0.4195
Echinococcus multilocularis muscleblind protein 1 0.0151 0.0508 0.0505
Schistosoma mansoni myst-related protein 0.0035 0.0051 0.0048
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0029
Plasmodium falciparum heat shock protein 90, putative 0.0057 0.0137 0.0948
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0061 0.0154 0.02
Loa Loa (eye worm) hypothetical protein 0.0441 0.1652 0.2212
Schistosoma mansoni microtubule-associated protein tau 0.1364 0.5286 0.5284
Plasmodium vivax SET domain protein, putative 0.0157 0.0532 0.386
Brugia malayi hypothetical protein 0.0029 0.0027 0.0029
Echinococcus granulosus uro adherence factor A 0.0024 0.0008 0.0005
Loa Loa (eye worm) hypothetical protein 0.0745 0.2848 0.3819
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0051 0.0116 0.0798
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0113 0.024
Brugia malayi nuclear receptor NHR-67 0.0029 0.0027 0.0029
Schistosoma mansoni phosphatidylserine receptor 0.0029 0.0027 0.0023
Trypanosoma brucei PAB1-binding protein , putative 0.0075 0.0211 0.213
Loa Loa (eye worm) latrophilin receptor protein 2 0.0082 0.0235 0.0309
Leishmania major heat shock protein 83-1 0.0097 0.0297 0.3056
Brugia malayi Papain family cysteine protease containing protein 0.0103 0.0319 0.0421
Giardia lamblia Cathepsin B precursor 0.0051 0.0113 0.0495
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0029 0.0029 0.0026
Schistosoma mansoni tar DNA-binding protein 0.0252 0.0907 0.0904
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0157 0.0532 0.5509
Schistosoma mansoni phd/f-box containing protein 0.0029 0.0027 0.0023
Trypanosoma brucei heat shock protein, putative 0.0097 0.0297 0.3038
Loa Loa (eye worm) hypothetical protein 0.0024 0.0008 0.0003
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0313
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0265 0.0959 0.0956
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0029
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0073 0.0203 0.0431
Echinococcus granulosus lysine specific demethylase 5A 0.0131 0.043 0.0427
Loa Loa (eye worm) hypothetical protein 0.0036 0.0054 0.0065
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0142 0.0473 0.047
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0029
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0024 0.0009 0.0006
Echinococcus granulosus cpg binding protein 0.0204 0.0716 0.0713
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0052 0.012 0.0153
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0051 0.0113 0.0776
Trypanosoma cruzi heat shock protein 85, putative 0.0097 0.0297 0.1017
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0051 0.0116 0.1161
Echinococcus granulosus Immunoglobulin 0.0029 0.0029 0.0026
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0051 0.0113 0.0495
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0029 0.0027 0.0024
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0029 0.0027 0.0029
Trichomonas vaginalis endoplasmin, putative 0.0071 0.0192 0.0407
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0061 0.0154 0.02
Brugia malayi intermediate filament protein 0.0026 0.0018 0.0017
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0065 0.0168 0.0165
Trypanosoma brucei heat shock protein, putative 0.0097 0.0297 0.3038
Echinococcus granulosus phd finger protein 10 0.0024 0.0008 0.0005
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0029 0.0028 0.0211
Mycobacterium tuberculosis Probable dehydrogenase 0.0338 0.1245 0.497
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0745 0.2848 1
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0033 0.0044 0.0153
Giardia lamblia PHD finger protein 15 0.0089 0.0263 0.2176
Entamoeba histolytica cysteine protease, putative 0.0051 0.0113 0.121
Schistosoma mansoni hypothetical protein 0.0082 0.0235 0.0232
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0657 0.25 1
Leishmania major basic transcription factor 3a, putative 0.0071 0.0192 0.1961
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0061 0.0154 0.02
Loa Loa (eye worm) PHD-finger family protein 0.0089 0.0263 0.0346
Plasmodium falciparum serine repeat antigen 1 0.0051 0.0113 0.0776
Giardia lamblia Cysteine protease 0.0051 0.0113 0.0495
Trypanosoma brucei heat shock protein, putative 0.0097 0.0297 0.3038
Trichomonas vaginalis glucosylceramidase, putative 0.0552 0.2087 0.4431
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0051 0.0116 0.0798
Echinococcus multilocularis cathepsin L cysteine protease 0.0111 0.035 0.0347
Loa Loa (eye worm) TK protein kinase 0.0024 0.0009 0.0005
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.006 0.015 0.1045
Brugia malayi CXXC zinc finger family protein 0.018 0.0622 0.0828
Loa Loa (eye worm) hypothetical protein 0.0046 0.0096 0.0122
Schistosoma mansoni hypothetical protein 0.0024 0.0008 0.0005
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0036 0.0054 0.0051
Trypanosoma brucei heat shock protein, putative 0.0097 0.0297 0.3038
Loa Loa (eye worm) ICD-1 protein 0.0071 0.0192 0.0251
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0798 0.3057 0.4099
Trypanosoma cruzi PAB1-binding protein , putative 0.0075 0.0211 0.0713
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0074 0.0158
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0313
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0018 0.0017
Brugia malayi PHD-finger family protein 0.0024 0.0008 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0074 0.0158
Loa Loa (eye worm) hypothetical protein 0.0061 0.0154 0.02
Loa Loa (eye worm) hypothetical protein 0.0051 0.0113 0.0145
Trichomonas vaginalis glucosylceramidase, putative 0.0524 0.1976 0.4195
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0152 0.0149
Schistosoma mansoni hypothetical protein 0.0024 0.0008 0.0005
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0018 0.0017
Schistosoma mansoni hypothetical protein 0.0147 0.0493 0.049
Echinococcus multilocularis cysteine protease 0.0111 0.035 0.0347
Brugia malayi Immunoglobulin I-set domain containing protein 0.0489 0.1841 0.2465
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0278 0.1011 0.1008
Loa Loa (eye worm) inositol-1 0.0073 0.0203 0.0265
Schistosoma mansoni methyl-cpg binding protein mbd 0.0122 0.0393 0.039
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0103 0.0319 0.327
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0029 0.0027 0.0029
Onchocerca volvulus 0.0026 0.0018 0.0027
Giardia lamblia Cathepsin B precursor 0.0051 0.0113 0.0495
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0061 0.0154 0.02
Giardia lamblia Hypothetical protein 0.0051 0.0113 0.0495
Brugia malayi hypothetical protein 0.0032 0.0041 0.0048
Loa Loa (eye worm) hypothetical protein 0.0075 0.0211 0.0276
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0051 0.0116 0.0149
Leishmania major cathepsin L-like protease 0.0111 0.035 0.3616
Trypanosoma brucei heat shock protein, putative 0.0097 0.0297 0.3038
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0142 0.0473 0.047
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0152 0.0149
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0035 0.0053 0.0049
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.0119 0.0253
Trypanosoma cruzi cysteine peptidase, putative 0.0111 0.035 0.1205
Schistosoma mansoni RAR-like nuclear receptor 0.0061 0.0154 0.0151
Entamoeba histolytica hypothetical protein 0.0025 0.0011 0.0067
Echinococcus multilocularis lamin dm0 0.0026 0.0018 0.0015
Schistosoma mansoni tyrosine kinase 0.1913 0.745 0.7449
Schistosoma mansoni nuclear hormone receptor 0.0061 0.0154 0.0151
Onchocerca volvulus 0.0111 0.035 0.0733
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0313
Echinococcus multilocularis musashi 0.0026 0.0018 0.0015
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0313
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.0041 0.0048
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0061 0.0154 0.02
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0051 0.0113 0.0776
Trypanosoma cruzi cysteine proteinase, putative 0.0103 0.0319 0.1095
Brugia malayi nuclear hormone receptor family member odr-7 0.0029 0.0027 0.0029
Echinococcus multilocularis histone acetyltransferase myst4 0.0024 0.0008 0.0005
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0029 0.0027 0.0024
Echinococcus granulosus cathepsin L cysteine proteinase 0.0111 0.035 0.0347
Schistosoma mansoni hypothetical protein 0.0082 0.0235 0.0232
Echinococcus multilocularis serine protein kinase ATM 0.0025 0.0011 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0059 0.0145 0.0307
Onchocerca volvulus 0.0029 0.0027 0.0046
Brugia malayi jmjC domain containing protein 0.0029 0.0027 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0045 0.0095
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0113 0.024
Echinococcus granulosus tar DNA binding protein 0.0252 0.0907 0.0904
Onchocerca volvulus Cathepsin L homolog 0.0111 0.035 0.0733
Echinococcus multilocularis cysteine protease 0.0111 0.035 0.0347
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0142 0.0473 0.047
Loa Loa (eye worm) TAR-binding protein 0.0252 0.0907 0.1211
Leishmania major heat shock protein 83-1 0.0097 0.0297 0.3056
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0008 0.0017
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0038 0.0062 0.0077
Echinococcus granulosus Nuclear hormone receptor HR96 0.0029 0.0027 0.0024
Echinococcus multilocularis lysine specific demethylase 6a 0.0029 0.0027 0.0023
Schistosoma mansoni tyrosine kinase 0.1014 0.3908 0.3906
Trypanosoma cruzi transcription factor btf3, putative 0.0071 0.0192 0.065
Schistosoma mansoni hypothetical protein 0.0034 0.0047 0.0044
Schistosoma mansoni nephrin 0.0037 0.0058 0.0055
Loa Loa (eye worm) PHD-finger family protein 0.0024 0.0008 0.0003
Echinococcus multilocularis cathepsin b 0.0745 0.2848 0.2846
Loa Loa (eye worm) cysteine protease 0.0111 0.035 0.0463
Brugia malayi PHD-finger family protein 0.0024 0.0008 0.0003
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0059 0.0147 0.0313
Loa Loa (eye worm) hypothetical protein 0.0294 0.1072 0.1432
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0051 0.0116 0.1138
Loa Loa (eye worm) hypothetical protein 0.0043 0.0085 0.0106
Loa Loa (eye worm) hypothetical protein 0.0051 0.0113 0.0145
Onchocerca volvulus 0.0029 0.0027 0.0046
Treponema pallidum heat shock protein 90 0.0091 0.0273 0.4403
Leishmania major heat shock protein 83-1 0.0097 0.0297 0.3056
Schistosoma mansoni atypical protein kinase C 0.01 0.0309 0.0306
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0073 0.0203 0.1436
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0313
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0313
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0061 0.0154 0.0151
Loa Loa (eye worm) hypothetical protein 0.0163 0.0555 0.0738
Echinococcus granulosus protein kinase c iota type 0.0094 0.0286 0.0283
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0069 0.0716
Loa Loa (eye worm) jmjC domain-containing protein 0.0131 0.043 0.0571
Echinococcus granulosus Nuclear hormone receptor HR96 0.0029 0.0027 0.0024
Brugia malayi nuclear receptor RXR 0.0029 0.0027 0.0029
Leishmania major heat shock protein 83-1 0.0097 0.0297 0.3056
Loa Loa (eye worm) hypothetical protein 0.0029 0.0029 0.0032
Echinococcus granulosus TAF3 RNA polymerase II TATA box binding protein 0.0024 0.0008 0.0005
Loa Loa (eye worm) jmjC domain-containing protein 0.0183 0.0635 0.0845
Loa Loa (eye worm) hypothetical protein 0.0059 0.0145 0.0187
Toxoplasma gondii cathepsin CPL 0.0111 0.035 0.2522
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0061 0.0154 0.02
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0051 0.0113 0.024
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.0119 0.0253
Loa Loa (eye worm) hypothetical protein 0.0461 0.1731 0.2317
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0051 0.0113 0.0495
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0061 0.0154 0.02
Onchocerca volvulus 0.0461 0.1731 0.3666
Entamoeba histolytica cysteine proteinase, putative 0.0111 0.035 0.3869
Brugia malayi Papain family cysteine protease containing protein 0.0051 0.0113 0.0145
Schistosoma mansoni cathepsin F (C01 family) 0.0111 0.035 0.0347
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0152 0.1063
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0615 0.2338 0.2336
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0163 0.0555 0.0552
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0142 0.0473 0.1004
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0061 0.0154 0.0151
Trichomonas vaginalis glucosylceramidase, putative 0.0798 0.3057 0.649
Schistosoma mansoni myelin transcription factor 1 myt1 0.0163 0.0555 0.0552
Brugia malayi jmjC domain containing protein 0.029 0.1057 0.1412
Schistosoma mansoni tyrosine kinase 0.1031 0.3974 0.3972
Trypanosoma cruzi heat shock protein 85, putative 0.0097 0.0297 0.1017
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0008 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0103 0.0319 0.0677
Schistosoma mansoni lamin 0.0026 0.0018 0.0015
Loa Loa (eye worm) hypothetical protein 0.0061 0.0154 0.02
Onchocerca volvulus 0.0061 0.0154 0.0316
Brugia malayi cathepsin L precursor 0.0051 0.0113 0.0145
Leishmania major hypothetical protein, conserved 0.0075 0.0211 0.2151
Echinococcus granulosus epidermal growth factor receptor 0.1913 0.745 0.7449
Trichomonas vaginalis inositol monophosphatase, putative 0.0073 0.0203 0.0431
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0029 0.0027 0.0024
Toxoplasma gondii FATC domain-containing protein 0.0025 0.0011 0.0026
Loa Loa (eye worm) hypothetical protein 0.0061 0.0154 0.02
Trypanosoma cruzi cysteine peptidase, putative 0.0157 0.0532 0.1845
Plasmodium vivax JmjC domain containing protein 0.0029 0.0027 0.0137
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0051 0.0113 0.011
Loa Loa (eye worm) jmjC domain-containing protein 0.0029 0.0027 0.0028
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0026 0.0017 0.0014
Giardia lamblia Cathepsin L-like protease 0.0051 0.0113 0.0495
Leishmania major cathepsin L-like protease 0.0111 0.035 0.3616
Schistosoma mansoni tyrosine kinase 0.0615 0.2338 0.2336
Schistosoma mansoni cathepsin C 0.0051 0.0113 0.011
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0074 0.0158
Echinococcus multilocularis Immunoglobulin 0.0029 0.0029 0.0026
Leishmania major heat shock protein 83-1 0.0097 0.0297 0.3056
Schistosoma mansoni hypothetical protein 0.0024 0.0008 0.0005
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0152 0.0588
Echinococcus multilocularis TAF3 RNA polymerase II, TATA box binding protein 0.0024 0.0008 0.0005
Echinococcus granulosus nuclear receptor nhr 48 0.0029 0.0027 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.035 0.0744
Echinococcus granulosus peregrin 0.0109 0.0343 0.034
Plasmodium falciparum zinc finger protein, putative 0.0035 0.0051 0.0318
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0089 0.0263 0.026
Onchocerca volvulus 0.0111 0.035 0.0733
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0025 0.0011 0.0008
Brugia malayi CHD4 protein 0.0035 0.0053 0.0063
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0061 0.0154 0.0151
Brugia malayi chromobox protein homolog 3 0.0039 0.0067 0.0083
Brugia malayi Muscleblind-like protein 0.0151 0.0508 0.0675
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0278 0.1011 0.1008
Schistosoma mansoni vesicular amine transporter 0.0029 0.0029 0.0026
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0157 0.0532 0.5509
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0103 0.0319 0.0316
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0061 0.0154 0.0151
Entamoeba histolytica cysteine protease, putative 0.0051 0.0113 0.121
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0051 0.0113 0.011
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0157 0.0532 0.5509
Toxoplasma gondii cathepsin B 0.0265 0.0959 0.7007
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0025 0.0011 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0074 0.0158
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0051 0.0116 0.0381
Schistosoma mansoni protein phosphatase 2C 0.0029 0.0027 0.0023
Echinococcus multilocularis protein tyrosine kinase 0.0808 0.3094 0.3092
Brugia malayi F/Y-rich N-terminus family protein 0.0103 0.032 0.0423
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0034 0.0047 0.0044
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0113 0.024
Schistosoma mansoni thyroid hormone receptor 0.0061 0.0154 0.0151
Giardia lamblia Cathepsin B precursor 0.0051 0.0113 0.0495
Entamoeba histolytica cysteine protease, putative 0.0051 0.0113 0.121
Leishmania major cathepsin L-like protease 0.0157 0.0532 0.552
Giardia lamblia Cysteine protease 0.0051 0.0113 0.0495
Brugia malayi Bromodomain containing protein 0.0277 0.1003 0.134
Loa Loa (eye worm) TK/EGFR protein kinase 0.1913 0.745 1
Entamoeba histolytica cysteine proteinase, putative 0.0111 0.035 0.3869
Toxoplasma gondii heat shock protein 75, putative 0.0065 0.0168 0.1182
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0061 0.0154 0.02
Brugia malayi Papain family cysteine protease containing protein 0.0103 0.0319 0.0421
Schistosoma mansoni tar DNA-binding protein 0.0252 0.0907 0.0904
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0313
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0111 0.035 0.0744
Echinococcus granulosus cathepsin L 0.0103 0.0319 0.0316
Echinococcus granulosus histone acetyltransferase KAT2B 0.006 0.015 0.0147
Brugia malayi mbt repeat family protein 0.0143 0.0477 0.0633
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0152 0.0588
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0051 0.0113 0.011
Loa Loa (eye worm) hypothetical protein 0.0026 0.0017 0.0015
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0051 0.0116 0.0444
Echinococcus multilocularis cathepsin b 0.0745 0.2848 0.2846
Toxoplasma gondii heat shock protein HSP90 0.0097 0.0297 0.2129
Schistosoma mansoni zinc finger protein 0.0109 0.0343 0.034
Plasmodium vivax thioredoxin reductase, putative 0.0148 0.0498 0.3607
Trypanosoma brucei ISWI complex protein 0.0109 0.0343 0.3527
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0143 0.0477 0.1001
Plasmodium falciparum serine repeat antigen 4 0.0051 0.0113 0.0776
Brugia malayi Matrixin family protein 0.0036 0.0054 0.0065
Schistosoma mansoni heat shock protein 0.0065 0.0168 0.0165
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0074 0.0158
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0065 0.0168 0.1828
Echinococcus granulosus lamin 0.0026 0.0018 0.0015
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0059 0.0147 0.1465
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0168 0.0577 0.0574
Loa Loa (eye worm) MBCTL1 0.0163 0.0555 0.0738
Schistosoma mansoni cpg binding protein 0.018 0.0622 0.0619
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.035 0.0744
Trichomonas vaginalis heat shock protein, putative 0.0071 0.0192 0.0407
Giardia lamblia Cathepsin L precursor 0.0051 0.0113 0.0495
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0313
Onchocerca volvulus Matrilysin homolog 0.0079 0.0225 0.0466
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0313
Plasmodium falciparum serine repeat antigen 8 0.0051 0.0113 0.0776
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.035 0.0744
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0022 0.0047
Brugia malayi Cathepsin L-like precursor 0.0111 0.035 0.0463
Giardia lamblia Cathepsin B precursor 0.0265 0.0959 1
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0052 0.0121 0.0117
Echinococcus multilocularis epidermal growth factor receptor 0.1913 0.745 0.7449
Leishmania major trypanothione reductase 0.0148 0.0498 0.5161
Plasmodium vivax heat shock protein 90, putative 0.0065 0.0168 0.1182
Brugia malayi Nuclear hormone receptor-like 1 0.0061 0.0154 0.02
Trypanosoma cruzi trypanothione reductase, putative 0.0051 0.0116 0.0381
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0111 0.035 0.2522
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.029 0.1057 0.1054
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0105 0.0326 0.1121
Echinococcus multilocularis 0.059 0.2239 0.2237
Brugia malayi RNA binding protein 0.0252 0.0907 0.1211
Brugia malayi hypothetical protein 0.0024 0.0008 0.0003
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0018 0.0017
Entamoeba histolytica hypothetical protein 0.0073 0.0203 0.2213
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0051 0.0113 0.024
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.035 0.0744
Onchocerca volvulus 0.0033 0.0046 0.0085
Brugia malayi jmjC domain containing protein 0.0029 0.0027 0.0028
Onchocerca volvulus 0.0059 0.0145 0.0296
Brugia malayi orphan nuclear receptor NR2E1 0.0029 0.0027 0.0029
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0142 0.0473 0.1004
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0026 0.0017 0.0015
Giardia lamblia Grp94/Hsp90 0.0091 0.0273 0.2294
Echinococcus multilocularis FTZ F1 alpha 0.0061 0.0154 0.0151
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0061 0.0154 0.02
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0029 0.0027 0.0024
Loa Loa (eye worm) mbt repeat family protein 0.0143 0.0477 0.0633
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0338 0.1245 0.497
Loa Loa (eye worm) hypothetical protein 0.0046 0.0096 0.0122
Brugia malayi jmjC domain containing protein 0.0131 0.043 0.0571
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0029
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0157 0.0532 0.386
Leishmania major heat shock protein 83-1 0.0097 0.0297 0.3056
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0051 0.0116 0.5
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0027 0.0024
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0338 0.1245 0.497
Toxoplasma gondii cathepsin CPC2 0.0051 0.0113 0.0776
Brugia malayi cathepsin Z-like cysteine proteinase 0.0051 0.0113 0.0145
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.1031 0.3974 0.3972
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0129 0.0423 0.042
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0113 0.024
Echinococcus granulosus fetal alzheimer antigen falz 0.0171 0.0587 0.0584
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0313
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0029 0.0027 0.0024
Brugia malayi cathepsin L-like cysteine proteinase 0.0051 0.0113 0.0145
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0051 0.0113 0.024
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0091 0.0273 0.2809
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0029 0.0027 0.0066
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0111 0.035 0.0744
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0051 0.0116 0.0381
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0029
Trypanosoma cruzi transcription factor btf3, putative 0.0071 0.0192 0.065
Schistosoma mansoni tyrosine kinase 0.1031 0.3974 0.3972
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0061 0.0154 0.02
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0074 0.0158
Trypanosoma cruzi major cysteine proteinase, putative 0.0051 0.0113 0.0371
Echinococcus granulosus FTZ F1 alpha 0.0061 0.0154 0.0151
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0265 0.0959 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0061 0.0154 0.0151
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0091 0.0273 1
Entamoeba histolytica cysteine protease, putative 0.0051 0.0113 0.121
Echinococcus granulosus thyroid hormone receptor alpha 0.0029 0.0027 0.0024
Schistosoma mansoni tar DNA-binding protein 0.0252 0.0907 0.0904
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0111 0.035 0.0744
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0051 0.0113 0.011
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0029 0.0027 0.0066
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0187 0.0397
Onchocerca volvulus 0.0036 0.0054 0.0103
Brugia malayi protein kinase C3,putative 0.0086 0.0254 0.0334
Echinococcus granulosus methyl CpG binding domain protein 2 0.0122 0.0393 0.039
Echinococcus multilocularis dnaJ subfamily B 0.2561 1 1
Brugia malayi hypothetical protein 0.0073 0.0203 0.0265
Echinococcus multilocularis thioredoxin glutathione reductase 0.0148 0.0498 0.0495
Schistosoma mansoni hypothetical protein 0.0024 0.0008 0.0005
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0061 0.0155 0.0152
Plasmodium falciparum heat shock protein 90 0.0097 0.0297 0.2129
Brugia malayi latrophilin 2 splice variant baaae 0.0176 0.0608 0.081
Onchocerca volvulus 0.0111 0.035 0.0733
Brugia malayi Immunoglobulin I-set domain containing protein 0.0029 0.0029 0.0032
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0061 0.0154 0.0151
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0074 0.0158
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0039 0.0067 0.0063
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0085 0.0247 0.0244
Plasmodium falciparum JmjC domain-containing protein, putative 0.0029 0.0027 0.0137
Leishmania major heat shock protein 83-1 0.0097 0.0297 0.3056
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0187 0.0397
Plasmodium falciparum glutathione reductase 0.0051 0.0116 0.0798
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0051 0.0113 0.0495
Loa Loa (eye worm) hypothetical protein 0.0024 0.0008 0.0003
Echinococcus granulosus JmjC domain containing protein 4 0.0029 0.0027 0.0023
Echinococcus granulosus ecdysone induced protein 78C 0.0061 0.0154 0.0151
Loa Loa (eye worm) hypothetical protein 0.0151 0.0508 0.0675
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.0203 0.02
Loa Loa (eye worm) hypothetical protein 0.0024 0.0008 0.0003
Echinococcus granulosus PHD finger protein 14 0.0024 0.0008 0.0005
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0142 0.0473 0.1004
Trichomonas vaginalis glucosylceramidase, putative 0.0798 0.3057 0.649
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0163 0.0555 0.0552
Plasmodium falciparum serine repeat antigen 6 0.0051 0.0113 0.0776
Toxoplasma gondii Hsp90 domain-containing protein 0.0369 0.1365 1
Echinococcus granulosus cathepsin l1 0.0059 0.0145 0.0141
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0061 0.0154 0.02
Echinococcus granulosus heat shock protein 0.0097 0.0297 0.0294
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0051 0.0116 0.1138
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0278 0.1011 0.1008
Echinococcus granulosus zinc finger protein 0.0153 0.0518 0.0515
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0073 0.0203 0.5512
Loa Loa (eye worm) hypothetical protein 0.0044 0.0088 0.0112
Brugia malayi hypothetical protein 0.0032 0.0041 0.0048
Schistosoma mansoni phd finger protein 0.0024 0.0008 0.0005
Brugia malayi Matrixin family protein 0.0086 0.0253 0.0332
Entamoeba histolytica cysteine protease, putative 0.0103 0.0319 0.3517
Brugia malayi Cathepsin L-like precursor 0.0059 0.0145 0.0187
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0157 0.0532 0.5509
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0119 0.0252
Brugia malayi ecdysone receptor 0.0029 0.0027 0.0029
Echinococcus granulosus SAM and MBT domain containing protein 0.0143 0.0477 0.0474
Echinococcus granulosus phd:f box containing protein 0.0029 0.0027 0.0023
Loa Loa (eye worm) hypothetical protein 0.0061 0.0154 0.02
Echinococcus multilocularis phd finger protein 12 0.0024 0.0008 0.0005
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0313
Echinococcus multilocularis SAM and MBT domain containing protein 0.0143 0.0477 0.0474
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0122 0.0393 0.039
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.004 0.0071 0.0466
Entamoeba histolytica cysteine protease, putative 0.0103 0.0319 0.3517
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0142 0.0473 0.0628
Brugia malayi Matrixin family protein 0.0036 0.0054 0.0065
Trypanosoma cruzi cysteine peptidase, putative 0.0052 0.012 0.0393
Echinococcus granulosus cathepsin b 0.0745 0.2848 0.2846
Entamoeba histolytica heat shock protein 90, putative 0.0097 0.0297 0.327
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.005 0.0112 0.0109
Mycobacterium tuberculosis Probable reductase 0.0338 0.1245 0.497
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0029
Echinococcus multilocularis thyroid hormone receptor alpha 0.0061 0.0154 0.0151
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0061 0.0154 0.02
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0051 0.0113 0.011
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0032 0.0041 0.0038
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.0203 0.02
Loa Loa (eye worm) hypothetical protein 0.0052 0.012 0.0153
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0061 0.0154 0.02
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0029 0.0028 0.0148
Brugia malayi Fibronectin type III domain containing protein 0.0029 0.0029 0.0032
Trypanosoma brucei Heat shock protein 83, putative 0.0097 0.0297 0.3038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.035 0.0744
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0111 0.035 0.0744
Entamoeba histolytica hypothetical protein 0.0073 0.0203 0.2213
Giardia lamblia Cysteine protease 0.0051 0.0113 0.0495
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0103 0.0319 0.0677
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0111 0.035 0.0463
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0032 0.0041 0.0048
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0059 0.0147 0.0313
Brugia malayi Heterochromatin protein 1 0.0069 0.0187 0.0244
Loa Loa (eye worm) heat shock protein 75 0.0065 0.0168 0.0219
Loa Loa (eye worm) hypothetical protein 0.0024 0.0008 0.0003
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0052 0.0119 0.0253
Trichomonas vaginalis glucosylceramidase, putative 0.0798 0.3057 0.649
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0029 0.0027 0.0046
Plasmodium vivax basic transcription factor 3b, putative 0.0071 0.0192 0.1359
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.0203 0.207
Onchocerca volvulus 0.0111 0.035 0.0733
Loa Loa (eye worm) CHromoDomain protein family member 0.0035 0.0053 0.0063
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0073 0.0203 0.0791
Onchocerca volvulus 0.0024 0.0008 0.0005
Loa Loa (eye worm) histone methyltransferase 0.0061 0.0155 0.0201
Trichomonas vaginalis glucosylceramidase, putative 0.0552 0.2087 0.4431
Brugia malayi Cathepsin L-like precursor 0.0059 0.0145 0.0187
Trypanosoma cruzi cysteine protease, putative 0.0103 0.0319 0.1095
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0256 0.0923 0.092
Echinococcus multilocularis GPCR, family 2 0.0082 0.0235 0.0232
Echinococcus multilocularis peregrin 0.0109 0.0343 0.034
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.035 0.0744
Echinococcus multilocularis epidermal growth factor receptor 0.1031 0.3974 0.3972
Loa Loa (eye worm) hypothetical protein 0.0051 0.0113 0.0145
Brugia malayi Bromodomain associated family protein 0.0024 0.0008 0.0003
Schistosoma mansoni zinc finger protein 0.0153 0.0518 0.0515
Echinococcus multilocularis geminin 0.1732 0.6737 0.6736
Giardia lamblia Cathepsin L-like protease 0.0051 0.0113 0.0495
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0142 0.0473 0.1004
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0028 0.0148
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0059 0.0147 0.0313
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0152 0.1539
Toxoplasma gondii NADPH-glutathione reductase 0.0051 0.0116 0.0798
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.006 0.015 0.1045
Plasmodium falciparum thioredoxin reductase 0.0148 0.0498 0.3607
Schistosoma mansoni heat shock protein 0.0097 0.0297 0.0294
Schistosoma mansoni cathepsin F (C01 family) 0.0111 0.035 0.0347
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0313
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0163 0.0557 0.0554
Entamoeba histolytica hypothetical protein 0.0051 0.0113 0.121
Echinococcus granulosus GPCR family 2 0.0082 0.0235 0.0232
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0026 0.0017 0.0036
Onchocerca volvulus 0.018 0.0622 0.1311
Echinococcus granulosus jumonji domain containing 1A 0.0029 0.0027 0.0023
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0029 0.0029 0.0026
Entamoeba histolytica cysteine protease, putative 0.0111 0.035 0.3869
Echinococcus multilocularis cathepsin L cysteine protease 0.0111 0.035 0.0347
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0059 0.0147 0.0313
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0061 0.0154 0.0151
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0338 0.1245 0.497
Echinococcus multilocularis histone acetyltransferase myst3 0.0024 0.0008 0.0005
Plasmodium falciparum cysteine proteinase falcipain 3 0.0111 0.035 0.2522
Giardia lamblia Cathepsin L precursor 0.0051 0.0113 0.0495
Trypanosoma cruzi heat shock protein 85, putative 0.0097 0.0297 0.1017
Schistosoma mansoni dpf3 0.0024 0.0008 0.0005
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0142 0.0473 0.1004
Echinococcus granulosus PHD finger protein rhinoceros 0.0089 0.0263 0.026
Loa Loa (eye worm) hypothetical protein 0.0024 0.0008 0.0003
Onchocerca volvulus 0.0434 0.1622 0.3435
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0745 0.2848 0.2846
Schistosoma mansoni tyrosine kinase 0.1014 0.3908 0.3906
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0029
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0029 0.0027 0.0024
Brugia malayi hypothetical protein 0.0029 0.0029 0.0032
Echinococcus multilocularis inositol monophosphatase 1 0.0073 0.0203 0.02
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0032 0.0041 0.0038
Schistosoma mansoni retinoic acid receptor RXR 0.0061 0.0154 0.0151
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0051 0.0116 0.1138
Trichomonas vaginalis helicase, putative 0.0041 0.0074 0.0158
Leishmania major heat shock protein 83-1 0.0097 0.0297 0.3056
Brugia malayi jmjC domain containing protein 0.0029 0.0027 0.0028
Schistosoma mansoni jumonji/arid domain-containing protein 0.0131 0.043 0.0427
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0152 0.0588
Toxoplasma gondii LsmAD domain-containing protein 0.0075 0.0211 0.1493
Brugia malayi cathepsin F-like cysteine proteinase 0.0052 0.012 0.0153
Loa Loa (eye worm) ctsf protein 0.0111 0.035 0.0463
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0029
Echinococcus multilocularis ecdysone induced protein 78C 0.0061 0.0154 0.0151
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0061 0.0154 0.0151
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0059 0.0147 0.0313
Brugia malayi SET domain containing protein 0.0033 0.0046 0.0054
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0073 0.0203 0.0686
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0029 0.0027 0.0196
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0033 0.0045 0.0095
Onchocerca volvulus Bile acid receptor homolog 0.0061 0.0154 0.0316
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0029
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0111 0.035 0.0744
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0142 0.0473 0.047
Toxoplasma gondii NAC domain-containing protein 0.0071 0.0192 0.1359
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0051 0.0116 0.0444
Loa Loa (eye worm) transcription factor SMAD2 0.0241 0.0862 0.115
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.0017
Echinococcus granulosus remodeling and spacing factor 1 0.0024 0.0008 0.0005
Schistosoma mansoni fyve-containing 0.0024 0.0008 0.0005
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0052 0.012 0.0153
Echinococcus multilocularis histone acetyltransferase MYST2 0.0163 0.0555 0.0552
Schistosoma mansoni hypothetical protein 0.0029 0.0028 0.0025
Echinococcus multilocularis chromobox protein 1 0.0069 0.0187 0.0184
Schistosoma mansoni coup transcription factor 0.0061 0.0154 0.0151
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0026 0.0017 0.0015
Plasmodium vivax vivapain-2 0.0111 0.035 0.2522
Brugia malayi tailless protein 0.0029 0.0027 0.0029
Mycobacterium ulcerans heat shock protein 90 0.0091 0.0273 0.1074
Brugia malayi Cathepsin L-like precursor 0.0111 0.035 0.0463
Schistosoma mansoni phd finger protein 0.0024 0.0008 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0061 0.0154 0.02
Plasmodium vivax endoplasmin, putative 0.0097 0.0297 0.2129
Loa Loa (eye worm) hypothetical protein 0.0032 0.0041 0.0048
Loa Loa (eye worm) hypothetical protein 0.0029 0.0029 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0067 0.0142
Echinococcus granulosus phd finger protein 12 0.0024 0.0008 0.0005
Schistosoma mansoni cathepsin s 0.0052 0.012 0.0116
Loa Loa (eye worm) PHD-finger family protein 0.0147 0.0493 0.0655
Loa Loa (eye worm) bromodomain containing protein 0.013 0.0424 0.0562
Loa Loa (eye worm) nuclear receptor NHR-67 0.0029 0.0027 0.0029
Loa Loa (eye worm) hypothetical protein 0.0111 0.035 0.0463
Brugia malayi beta-NAC-like protein 0.0071 0.0192 0.0251
Entamoeba histolytica cysteine protease, putative 0.0103 0.0319 0.3517
Echinococcus multilocularis cathepsin L 0.0051 0.0113 0.011
Schistosoma mansoni chromobox protein 0.0069 0.0187 0.0184
Schistosoma mansoni transcription factor btf3 0.0071 0.0192 0.0189
Onchocerca volvulus 0.0111 0.035 0.0733
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0029 0.0027 0.0024

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.32 nM In vitro inhibitory activity against angiotensin II rabbit aorta AT1 receptor using radioligand [125I]-Sar Ile-AII ChEMBL. 8064808
IC50 (binding) = 0.32 nM In vitro inhibitory activity against angiotensin II rabbit aorta AT1 receptor using radioligand [125I]-Sar Ile-AII ChEMBL. 8064808
IC50 (binding) = 82 nM In vitro inhibitory activity against angiotensin II rat midbrain AT2 receptor using radioligand [125I]-Sar Ile-AII ChEMBL. 8064808
IC50 (binding) = 82 nM In vitro inhibitory activity against angiotensin II rat midbrain AT2 receptor using radioligand [125I]-Sar Ile-AII ChEMBL. 8064808

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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