Detailed information for compound 1568366

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 585.733 | Formula: C28H51N5O8
  • H donors: 7 H acceptors: 8 LogP: 1.17 Rotable bonds: 27
    Rule of 5 violations (Lipinski): 3
  • SMILES: CCCCCCCCCCC[C@H](CC(=O)N[C@H](C(=O)N[C@@H](C(CC(=O)N)O)C(=O)N[C@@H](C(C)C)C=O)CC(=O)N)O
  • InChi: 1S/C28H51N5O8/c1-4-5-6-7-8-9-10-11-12-13-19(35)14-25(39)31-20(15-23(29)37)27(40)33-26(22(36)16-24(30)38)28(41)32-21(17-34)18(2)3/h17-22,26,35-36H,4-16H2,1-3H3,(H2,29,37)(H2,30,38)(H,31,39)(H,32,41)(H,33,40)/t19-,20+,21-,22?,26+/m1/s1
  • InChiKey: DRAFAQFSRNBNLD-UZAKACFQSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0007 0.0017 0.0021
Echinococcus granulosus Endonuclease G 0.0008 0.0036 0.0037
Mycobacterium ulcerans carbohydrate kinase CbhK 0.0074 0.0878 0.2519
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0007 0.0021 0.0018
Schistosoma mansoni gliotactin 0.0023 0.0228 0.027
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0007 0.0029 0.0028
Mycobacterium ulcerans beta-lactamase 0.0035 0.0381 0.108
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0276 0.346 1
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0096 0.1162 0.1406
Echinococcus multilocularis replication factor c subunit 1 0.001 0.0056 0.005
Onchocerca volvulus 0.0024 0.0243 0.0289
Echinococcus multilocularis neuroligin 0.0023 0.0228 0.0222
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0056 0.0055
Loa Loa (eye worm) hypothetical protein 0.0074 0.0878 0.1062
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0007 0.0017 0.0011
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.015 0.1858 0.5359
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0013 0.0104 0.012
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.001 0.0056 0.0055
Loa Loa (eye worm) MH2 domain-containing protein 0.0324 0.4082 0.4963
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0087 0.1042 0.1268
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0308 0.3873 0.5513
Loa Loa (eye worm) hypothetical protein 0.0136 0.1675 0.2033
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0381 0.108
Schistosoma mansoni inositol monophosphatase 0.0036 0.0392 0.047
Schistosoma mansoni adenosine kinase 0.0648 0.8219 1
Loa Loa (eye worm) MH2 domain-containing protein 0.001 0.006 0.0066
Brugia malayi cytochrome P450 0.0006 0.0008 0.0003
Schistosoma mansoni survival motor neuron protein 0.0047 0.0532 0.0641
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0007 0.0017 0.0014
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0532 0.6746 0.9622
Brugia malayi glutathione reductase 0.0019 0.0174 0.0206
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0065 0.0763 0.0922
Echinococcus granulosus histone acetyltransferase KAT2B 0.0156 0.1931 0.2344
Brugia malayi neuropeptide F receptor 0.0024 0.0243 0.0289
Brugia malayi Type I phosphodiesterase / nucleotide pyrophosphatase family protein 0.0013 0.0104 0.012
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0052 0.0057
Onchocerca volvulus 0.0035 0.0381 0.0479
Onchocerca volvulus 0.0013 0.0104 0.0097
Echinococcus granulosus neuropeptide Y receptor 0.0024 0.0243 0.0289
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0007 0.0021 0.0018
Echinococcus granulosus alpha 1A adrenergic receptor 0.0024 0.0243 0.0289
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0056 0.0055
Mycobacterium ulcerans hypothetical protein 0.0026 0.0271 0.0761
Schistosoma mansoni Smad4 0.001 0.006 0.0066
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0024 0.0243 0.0289
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.002 0.0005
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0381 0.108
Trypanosoma cruzi nucleobase transporter, putative 0.0096 0.1162 0.1412
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0065 0.0763 0.0922
Onchocerca volvulus 0.001 0.0063 0.004
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0065 0.0763 0.0925
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.001 0.0063 0.0067
Schistosoma mansoni hypothetical protein 0.0177 0.2201 0.2672
Brugia malayi G protein-coupled receptor F59B2.13 0.0024 0.0243 0.0289
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0065 0.0763 0.1066
Schistosoma mansoni hypothetical protein 0.0029 0.0302 0.0361
Brugia malayi larval opioid receptor 0.0024 0.0243 0.0289
Loa Loa (eye worm) hypothetical protein 0.0018 0.0159 0.0187
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0007 0.0021 0.0005
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0087 0.1042 1
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.1956 0.1951
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.001 0.0063 0.0159
Trypanosoma brucei ribokinase, putative 0.0074 0.0878 0.1059
Loa Loa (eye worm) MH1 domain-containing protein 0.0022 0.0216 0.0256
Entamoeba histolytica acetyltransferase, GNAT family 0.0043 0.0487 0.0668
Leishmania major adenosine kinase-like protein 0.0074 0.0878 0.1065
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0007 0.0021 0.0005
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.001 0.0056 0.0055
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0065 0.0763 0.7274
Brugia malayi AKH receptor 0.0024 0.0243 0.0289
Brugia malayi MH1 domain containing protein 0.0022 0.0216 0.0256
Trichomonas vaginalis adenosine diphosphatase, putative 0.0017 0.0156 0.0198
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0381 0.108
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0381 0.108
Onchocerca volvulus Huntingtin homolog 0.0119 0.1454 0.1962
Toxoplasma gondii GDA1/CD39 (nucleoside phosphatase) family protein 0.0017 0.0156 0.0189
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0159 0.0439
Loa Loa (eye worm) isocitrate dehydrogenase 0.0029 0.031 0.037
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0026 0.0271 0.0761
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0065 0.0763 0.1066
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0087 0.1042 0.2659
Brugia malayi hypothetical protein 0.0024 0.0243 0.0289
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0101 0.012
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0268 0.032
Plasmodium falciparum thioredoxin reductase 0.0019 0.0174 0.1536
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0022 0.0216 0.0211
Trypanosoma cruzi hypothetical protein, conserved 0.0065 0.0763 0.0925
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0007 0.0017 0.0018
Mycobacterium tuberculosis Conserved protein 0.0035 0.0381 0.108
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0553 0.7011 1
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0065 0.0763 0.0919
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.003 0.0315 0.0774
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0029 0.031 0.037
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.002 0.0005
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0308 0.3873 0.5513
Trypanosoma brucei endonuclease G, putative 0.0008 0.0036 0.0034
Trichomonas vaginalis adenosine diphosphatase, putative 0.0017 0.0156 0.0198
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.001 0.0056 0.0138
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0065 0.0763 0.0922
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0013 0.0104 0.012
Trypanosoma cruzi nucleoside transporter-like, putative 0.0096 0.1162 0.1412
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0381 0.052
Loa Loa (eye worm) hypothetical protein 0.0018 0.0159 0.0187
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0065 0.0763 0.1066
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0185 0.0223
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.001 0.0063 0.0159
Trichomonas vaginalis DNA helicase recq1, putative 0.0008 0.0033 0.0023
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.001 0.0056 0.0258
Mycobacterium tuberculosis 6-phosphofructokinase PfkB (phosphohexokinase) (phosphofructokinase) 0.0074 0.0878 0.2519
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0065 0.0763 0.0922
Trypanosoma brucei PAB1-binding protein , putative 0.0047 0.0534 0.0641
Entamoeba histolytica ribokinase, putative 0.0074 0.0878 0.1226
Trypanosoma cruzi FHA domain containing protein, putative 0.001 0.0056 0.0065
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0243 0.0289
Schistosoma mansoni smad 0.001 0.006 0.0066
Loa Loa (eye worm) hypothetical protein 0.0023 0.0228 0.027
Plasmodium vivax acetyl-CoA synthetase, putative 0.001 0.0063 0.0594
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0185 0.0216
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0141 0.0387
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0156 0.0198
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0024 0.0243 0.0237
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0007 0.0017 0.0026
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0065 0.0763 0.0757
Onchocerca volvulus Putative pyridoxal kinase 0.0074 0.0878 0.1165
Plasmodium falciparum replication factor C subunit 1, putative 0.001 0.0056 0.0377
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0185 0.0218
Echinococcus multilocularis acetylcholinesterase 0.0136 0.1675 0.167
Trypanosoma brucei hypothetical protein, conserved 0.0065 0.0763 0.0919
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0006 0.0008 0.0007
Schistosoma mansoni opsin-like receptor 0.0024 0.0243 0.0289
Schistosoma mansoni cpg binding protein 0.0032 0.034 0.0407
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0022 0.0215 0.0209
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0159 0.0439
Leishmania major glycosyl hydrolase-like protein 0.0013 0.0101 0.012
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0065 0.0763 0.0925
Mycobacterium ulcerans acyl-CoA synthetase 0.001 0.0063 0.0159
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0013 0.0104 0.0119
Brugia malayi beta-lactamase family protein 0.0035 0.0381 0.0457
Toxoplasma gondii GDA1/CD39 (nucleoside phosphatase) family protein 0.0017 0.0156 0.0189
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0065 0.0763 0.1066
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0087 0.1042 0.1037
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0185 0.177
Echinococcus multilocularis neuropeptide receptor 0.0024 0.0243 0.0237
Onchocerca volvulus Equilibrative nucleoside transporter, putative homolog 0.0553 0.7011 0.9635
Echinococcus granulosus acetylcholinesterase 0.0136 0.1675 0.2033
Entamoeba histolytica fructokinase, putative 0.0074 0.0878 0.1226
Plasmodium falciparum glutathione reductase 0.0019 0.0174 0.1536
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0013 0.0101 0.012
Loa Loa (eye worm) cytochrome P450 family protein 0.0006 0.0008 0.0003
Giardia lamblia Fructose-bisphosphate aldolase 0.0308 0.3873 0.5513
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0268 0.032
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0141 0.0387
Loa Loa (eye worm) hypothetical protein 0.0018 0.0159 0.0187
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0185 0.0223
Echinococcus granulosus g protein coupled receptor 0.0024 0.0243 0.0289
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0065 0.0763 0.0928
Loa Loa (eye worm) hypothetical protein 0.0074 0.0878 0.1062
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0013 0.0104 0.0099
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0013 0.01 0.0112
Trichomonas vaginalis adenosine diphosphatase, putative 0.0017 0.0156 0.0198
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0026 0.0271 0.0761
Onchocerca volvulus Mothers against decapentaplegic homolog 0.001 0.006 0.0036
Brugia malayi MH2 domain containing protein 0.0022 0.0216 0.0256
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0023 0.0228 0.027
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0043 0.0483 0.1377
Trichomonas vaginalis ribokinase, putative 0.0074 0.0878 0.1231
Brugia malayi DKFZp564C0469 protein 0.001 0.0056 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0763 0.1066
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0007 0.0017 0.0011
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0007 0.0017 0.0018
Echinococcus multilocularis lysosomal alpha glucosidase 0.0158 0.1956 0.1951
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0308 0.3873 0.5513
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.002 0.0005
Echinococcus multilocularis neuropeptide Y receptor 0.0024 0.0243 0.0237
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0048 0.0552 0.0665
Brugia malayi AMP-binding enzyme family protein 0.001 0.0063 0.0069
Onchocerca volvulus 0.0024 0.0243 0.0289
Loa Loa (eye worm) G-protein coupled receptor 0.0024 0.0243 0.0289
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0161 0.1988 0.1984
Toxoplasma gondii GDA1/CD39 (nucleoside phosphatase) family protein 0.0026 0.0271 0.0329
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0007 0.0017 0.0018
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.015 0.1858 1
Onchocerca volvulus 0.0024 0.0243 0.0289
Echinococcus multilocularis neuropeptide Y receptor 0.0024 0.0243 0.0237
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0024 0.0243 0.0289
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0007 0.0021 0.0015
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0087 0.1042 0.2996
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0129 0.0124
Loa Loa (eye worm) hypothetical protein 0.0006 0.0013 0.0009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0243 0.0289
Echinococcus multilocularis neuropeptides capa receptor 0.0024 0.0243 0.0237
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0013 0.0101 0.012
Echinococcus multilocularis Polycystic kidney disease protein 0.0008 0.0034 0.0028
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0007 0.0021 0.0005
Entamoeba histolytica hypothetical protein 0.0035 0.038 0.0514
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0052 0.0596 0.0719
Toxoplasma gondii nucleoside transporter protein 0.0096 0.1162 0.1414
Onchocerca volvulus 0.0047 0.0532 0.0688
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.002 0.0005
Toxoplasma gondii DNA/RNA non-specific endonuclease 0.0008 0.0036 0.0044
Loa Loa (eye worm) hypothetical protein 0.0035 0.0381 0.0457
Trypanosoma brucei glycosyl hydrolase-like protein 0.0013 0.0101 0.0113
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0101 0.012
Schistosoma mansoni neuropeptide f receptor 76f 0.0024 0.0243 0.0289
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0024 0.0243 0.0237
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0065 0.0767 0.0927
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0048 0.0545 0.1555
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0532 0.0641
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0057 0.066 0.1889
Toxoplasma gondii LsmAD domain-containing protein 0.0047 0.0534 0.065
Echinococcus granulosus g-protein coupled receptor 0.0024 0.0243 0.0289
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0029 0.031 0.0374
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0024 0.0243 0.0289
Trichomonas vaginalis ribokinase, putative 0.0074 0.0878 0.1231
Echinococcus multilocularis BC026374 protein (S09 family) 0.0023 0.0228 0.0222
Echinococcus granulosus histone acetyltransferase KAT2B 0.0047 0.0538 0.0648
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0243 0.0237
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.015 0.1858 0.5359
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0007 0.0021 0.0018
Echinococcus granulosus 7TM GPCR rhodopsin 0.0024 0.0243 0.0289
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0243 0.0289
Echinococcus granulosus lamin 0.0026 0.0268 0.032
Echinococcus granulosus tar DNA binding protein 0.0052 0.0596 0.0719
Onchocerca volvulus 0.001 0.0063 0.004
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0013 0.0104 0.0099
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.001 0.0063 0.0076
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Brugia malayi Smad1 0.0022 0.0216 0.0256
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0007 0.0021 0.0018
Toxoplasma gondii exonuclease III APE 0.002 0.0185 0.0225
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0007 0.0021 0.0005
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0185 0.0436
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0013 0.0104 0.0099
Trypanosoma brucei nucleobase/nucleoside transporter 8.1 0.0096 0.1162 0.1406
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Brugia malayi Bloom's syndrome protein homolog 0.0008 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0017 0.0156 0.0183
Loa Loa (eye worm) MH1 domain-containing protein 0.001 0.006 0.0066
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0243 0.0289
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0158 0.1956 0.2374
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0243 0.0289
Echinococcus multilocularis expressed protein 0.0013 0.0104 0.0098
Onchocerca volvulus 0.0574 0.7275 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0129 0.015
Loa Loa (eye worm) hypothetical protein 0.0087 0.1042 0.1262
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0007 0.0021 0.0018
Leishmania major trypanothione reductase 0.0019 0.0174 0.021
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0013 0.0104 0.012
Loa Loa (eye worm) RNA binding protein 0.0052 0.0596 0.0719
Entamoeba histolytica kinase, PfkB family 0.0074 0.0878 0.1226
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0065 0.0763 0.1066
Echinococcus multilocularis equilibrative nucleoside transporter 3 0.0457 0.5782 0.5779
Trypanosoma brucei adenosine transporter 2, putative 0.0096 0.1162 0.1406
Entamoeba histolytica Hypothetical protein T24C12.3, putative 0.0074 0.0878 0.1226
Loa Loa (eye worm) hypothetical protein 0.0047 0.0534 0.0643
Echinococcus granulosus geminin 0.0177 0.2201 0.2672
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0043 0.0483 0.1377
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.1187 0.1438
Schistosoma mansoni tar DNA-binding protein 0.0052 0.0596 0.0719
Echinococcus granulosus 3'partial|ectonucleoside triphosphate diphosphohydrolase 0.0017 0.0156 0.0183
Echinococcus multilocularis neuropeptides capa receptor 0.0024 0.0243 0.0237
Loa Loa (eye worm) hypothetical protein 0.0035 0.0381 0.0457
Schistosoma mansoni smad1 5 8 and 0.0022 0.0216 0.0256
Onchocerca volvulus 0.001 0.0063 0.004
Schistosoma mansoni hypothetical protein 0.0015 0.0129 0.015
Loa Loa (eye worm) hypothetical protein 0.0007 0.0021 0.0018
Schistosoma mansoni cpg binding protein 0.0032 0.034 0.0407
Echinococcus granulosus ribokinase 0.0074 0.0878 0.1062
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0185 0.0235
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0065 0.0763 0.0925
Onchocerca volvulus 0.0035 0.0381 0.0479
Brugia malayi hypothetical protein 0.0119 0.1454 0.1764
Brugia malayi hypothetical protein 0.0047 0.0534 0.0643
Onchocerca volvulus 0.0035 0.0381 0.0479
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0065 0.0763 0.1066
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0185 0.164
Trichomonas vaginalis helicase, putative 0.0007 0.002 0.0005
Toxoplasma gondii ATPase, AAA family protein 0.001 0.0056 0.0068
Echinococcus granulosus smad 0.0022 0.0216 0.0256
Brugia malayi beta-lactamase family protein 0.0035 0.0381 0.0457
Entamoeba histolytica hypothetical protein 0.0035 0.038 0.0514
Brugia malayi hypothetical protein 0.0024 0.0243 0.0289
Trypanosoma cruzi hypothetical protein, conserved 0.0065 0.0763 0.0925
Brugia malayi RE15519p 0.0024 0.0243 0.0289
Echinococcus multilocularis neuropeptide receptor 0.0024 0.0243 0.0237
Loa Loa (eye worm) CYP4Cod1 0.0006 0.0008 0.0003
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0308 0.3873 0.5511
Echinococcus granulosus dro:myosuppressin receptor 0.0024 0.0243 0.0289
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0271 0.0761
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0024 0.0243 0.0237
Brugia malayi neuropeptide F receptor 0.0024 0.0243 0.0289
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0047 0.0538 0.0654
Leishmania major hypothetical protein, conserved 0.0035 0.0381 0.0461
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Mycobacterium ulcerans acetyl-CoA synthetase 0.001 0.0063 0.0159
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0532 0.6746 0.8208
Echinococcus granulosus tm gpcr rhodopsin 0.0024 0.0243 0.0289
Schistosoma mansoni hypothetical protein 0.0177 0.2201 0.2672
Onchocerca volvulus 0.0024 0.0243 0.0289
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0013 0.0104 0.012
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0006 0.0008 0.0007
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0136 0.1675 0.2033
Plasmodium vivax nucleoside-diphosphatase mig-23, putative 0.0017 0.0156 0.1487
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0007 0.0017 0.0011
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0047 0.0538 0.5156
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0065 0.0763 0.0925
Loa Loa (eye worm) carboxylesterase 0.0023 0.0228 0.027
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0024 0.0243 0.0289
Echinococcus multilocularis equilibrative nucleoside transporter 3 0.0553 0.7011 0.7009
Echinococcus granulosus ectonucleoside triphosphate diphosphohydrolase 0.0017 0.0156 0.0183
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0382 0.0465
Echinococcus multilocularis dro:myosuppressin receptor 0.0024 0.0243 0.0237
Schistosoma mansoni smad1 5 8 and 0.0022 0.0216 0.0256
Trypanosoma brucei unspecified product 0.0096 0.1162 0.1406
Echinococcus multilocularis mothers against decapentaplegic 2 0.001 0.006 0.0054
Trypanosoma cruzi trypanothione reductase, putative 0.0019 0.0174 0.021
Brugia malayi hypothetical protein 0.001 0.0056 0.0061
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0024 0.0243 0.0237
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0382 0.0522
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0382 0.0462
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0007 0.0029 0.0028
Schistosoma mansoni polycystin 1-related 0.0008 0.0034 0.0034
Echinococcus multilocularis RUN 0.0008 0.0034 0.0028
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0532 0.6746 0.6744
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0029 0.031 0.037
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0065 0.0763 0.0928
Trypanosoma cruzi cytochrome P450, putative 0.0006 0.0008 0.0007
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.038 0.0456
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0024 0.0243 0.0289
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0096 0.1162 0.1406
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0344 0.1816
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0392 0.0531
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0065 0.0763 0.0922
Loa Loa (eye worm) hypothetical protein 0.0553 0.7011 0.8529
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0381 0.108
Loa Loa (eye worm) hypothetical protein 0.0008 0.0034 0.0034
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0021 0.0203 0.0197
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0096 0.1162 0.1406
Leishmania major putative PfkB family sugar kinase 0.0074 0.0878 0.1065
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Brugia malayi hypothetical protein 0.0553 0.7011 0.8529
Plasmodium falciparum acetyl-CoA synthetase, putative 0.001 0.0063 0.0446
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0065 0.0763 0.1066
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.001 0.0063 0.0159
Brugia malayi Cytochrome P450 family protein 0.0006 0.0008 0.0003
Echinococcus multilocularis G-protein coupled receptor, putative 0.0024 0.0243 0.0237
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0763 0.1066
Plasmodium falciparum apyrase, putative 0.0017 0.0156 0.1353
Onchocerca volvulus 0.001 0.0056 0.003
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0065 0.0763 0.0922
Trypanosoma brucei adenosine transporter 2 0.0096 0.1162 0.1406
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0007 0.0017 0.0018
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0096 0.1162 0.1638
Trichomonas vaginalis antibiotic synthetase, putative 0.001 0.0063 0.0065
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0029 0.031 0.0374
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.001 0.0063 0.0159
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.0767 0.0927
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.001 0.0063 0.0074
Leishmania major endonuclease G, putative 0.0008 0.0036 0.0041
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0382 0.0522
Echinococcus multilocularis mothers against decapentaplegic 5 0.0022 0.0216 0.0211
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0007 0.0021 0.0015
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0098 0.1187 0.1182
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0024 0.0243 0.0237
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.001 0.0063 0.0159
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0382 0.0458
Brugia malayi hypothetical protein 0.0023 0.0228 0.027
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0065 0.0767 0.0931
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0381 0.108
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0007 0.0017 0.0018
Echinococcus granulosus allatostatin A receptor 0.0024 0.0243 0.0289
Loa Loa (eye worm) hypothetical protein 0.0532 0.6746 0.8206
Onchocerca volvulus 0.0023 0.0228 0.0268
Onchocerca volvulus 0.003 0.0318 0.0392
Brugia malayi hypothetical protein 0.0035 0.038 0.0456
Onchocerca volvulus 0.0023 0.0228 0.0268
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0087 0.1042 1
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0104 0.0124
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0007 0.0021 0.0015
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0065 0.0763 0.0922
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0057 0.066 0.3526
Trypanosoma cruzi endonuclease G, putative 0.0008 0.0036 0.0041
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0129 0.015
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0065 0.0763 0.0922
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.038 0.0375
Brugia malayi Carboxylesterase family protein 0.0023 0.0228 0.027
Leishmania major hypothetical protein, conserved 0.0065 0.0763 0.0925
Toxoplasma gondii NTPase II 0.0017 0.0156 0.0189
Echinococcus multilocularis g-protein coupled receptor 0.0024 0.0243 0.0237
Brugia malayi RNA recognition motif domain containing protein 0.0052 0.0596 0.0719
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0087 0.1042 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0024 0.0243 0.0289
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0056 0.0065
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0013 0.0101 0.012
Loa Loa (eye worm) beta-lactamase 0.0035 0.0381 0.0457
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.001 0.0063 0.0069
Echinococcus granulosus survival motor neuron protein 1 0.0229 0.2869 0.3486
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.002 0.0005
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0767 0.2198
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0065 0.0763 0.0922
Brugia malayi Glycosyl hydrolases family 31 protein 0.0158 0.1956 0.2374
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0271 0.0761
Brugia malayi ORL1-like opioid receptor 0.0024 0.0243 0.0289
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0392 0.0536
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0029 0.031 0.0304
Onchocerca volvulus Equilibrative nucleoside transporter, putative homolog 0.0553 0.7011 0.9635
Brugia malayi hypothetical protein 0.0024 0.0243 0.0289
Trichomonas vaginalis bromodomain-containing protein, putative 0.0047 0.0538 0.0745
Toxoplasma gondii isocitrate dehydrogenase 0.0029 0.031 0.0377
Brugia malayi Serotonin receptor 0.0024 0.0243 0.0289
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0023 0.0228 0.0637
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0065 0.0763 0.1066
Trypanosoma cruzi endonuclease G, putative 0.0008 0.0036 0.0041
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0065 0.0767 0.2198
Schistosoma mansoni acetyl-CoA synthetase 0.001 0.0063 0.0069
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0065 0.0763 0.1066
Leishmania major cAMP-specific phosphodiesterase, putative 0.0065 0.0763 0.0925
Trypanosoma brucei unspecified product 0.0096 0.1162 0.1406
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0026 0.0271 0.0761
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0185 0.0218
Brugia malayi Dopamine receptor 0.0024 0.0243 0.0289
Plasmodium vivax ataxin-2 like protein, putative 0.0047 0.0534 0.5119
Schistosoma mansoni adenosine kinase 0.0648 0.8219 1
Echinococcus granulosus acetylcholinesterase 0.0136 0.1675 0.2033
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0096 0.1162 0.1406
Schistosoma mansoni ap endonuclease 0.002 0.0185 0.0218
Schistosoma mansoni blooms syndrome DNA helicase 0.0006 0.0012 0.0008
Plasmodium falciparum phosphodiesterase delta, putative 0.0065 0.0763 0.7274
Plasmodium falciparum histone acetyltransferase GCN5 0.0043 0.0487 0.4589
Mycobacterium tuberculosis Adenosine kinase 0.0074 0.0878 0.2519
Leishmania major nucleobase transporter 0.0096 0.1162 0.1412
Trypanosoma cruzi nucleobase transporter, putative 0.0096 0.1162 0.1412
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0243 0.0289
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0019 0.0174 0.0483
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0065 0.0763 0.0928
Schistosoma mansoni neuropeptide receptor 0.0024 0.0243 0.0289
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0098 0.1187 0.1438
Echinococcus granulosus thioredoxin glutathione reductase 0.0019 0.0174 0.0206
Echinococcus multilocularis g protein coupled receptor 0.0024 0.0243 0.0237
Entamoeba histolytica hypothetical protein 0.0035 0.038 0.0514
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0532 0.6746 0.8206
Brugia malayi Nucleoside transporter family protein 0.0553 0.7011 0.8529
Plasmodium falciparum ataxin-2 like protein, putative 0.0047 0.0534 0.5043
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Loa Loa (eye worm) hypothetical protein 0.001 0.0056 0.0061
Echinococcus multilocularis isocitrate dehydrogenase 0.0029 0.031 0.0304
Loa Loa (eye worm) carboxylesterase 0.0023 0.0228 0.027
Echinococcus multilocularis lipoxygenase domain containing protein 0.0008 0.0034 0.0028
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0065 0.0763 0.1066
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0223 0.2791 0.8063
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0065 0.0763 0.0922
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0029 0.031 0.0368
Loa Loa (eye worm) PDE1B protein 0.0065 0.0763 0.0922
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0065 0.0763 0.0928
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0024 0.0243 0.0289
Schistosoma mansoni ap endonuclease 0.002 0.0185 0.0218
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0065 0.0763 0.0928
Echinococcus multilocularis ectonucleoside triphosphate diphosphohydrolase 0.0017 0.0156 0.015
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0009 0.0045 0.0107
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0243 0.0289
Echinococcus multilocularis sex peptide receptor 0.0024 0.0243 0.0237
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0065 0.0763 0.0928
Echinococcus multilocularis acetylcholinesterase 0.0136 0.1675 0.167
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0024 0.0243 0.0289
Echinococcus multilocularis geminin 0.0177 0.2201 0.2196
Schistosoma mansoni hypothetical protein 0.0428 0.5406 0.6575
Brugia malayi hypothetical protein 0.0229 0.2869 0.3486
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0101 0.012
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.001 0.0063 0.0076
Brugia malayi GnHR receptor homolog 0.0024 0.0243 0.0289
Toxoplasma gondii nucleoside transporter protein 0.0096 0.1162 0.1414
Trypanosoma brucei acetyl-CoA synthetase, putative 0.001 0.0063 0.0067
Toxoplasma gondii NADPH-glutathione reductase 0.0007 0.0017 0.0021
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0381 0.0457
Loa Loa (eye worm) hypothetical protein 0.0026 0.0271 0.0323
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0024 0.0243 0.0289
Echinococcus multilocularis equilibrative nucleoside transporter protein 0.0553 0.7011 0.7009
Loa Loa (eye worm) hypothetical protein 0.0012 0.0089 0.0101
Loa Loa (eye worm) hypothetical protein 0.0007 0.0021 0.0018
Mycobacterium ulcerans acyl-CoA synthetase 0.001 0.0063 0.0159
Schistosoma mansoni smad 0.0022 0.0216 0.0256
Plasmodium falciparum phosphodiesterase gamma, putative 0.0065 0.0763 0.7274
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0022 0.0215 0.0255
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Schistosoma mansoni adenosine diphosphatase 0.0026 0.0271 0.0322
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0065 0.0763 0.1066
Onchocerca volvulus Ribokinase homolog 0.0074 0.0878 0.1165
Brugia malayi MH2 domain containing protein 0.001 0.006 0.0066
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0023 0.0228 0.0301
Brugia malayi MH1 domain containing protein 0.0022 0.0216 0.0256
Trypanosoma brucei adenosine kinase, putative 0.0648 0.8219 1
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0023 0.0228 0.027
Onchocerca volvulus 0.0024 0.0243 0.0289
Schistosoma mansoni biogenic amine receptor 0.0024 0.0243 0.0289
Brugia malayi hypothetical protein 0.0024 0.0243 0.0289
Echinococcus granulosus lipoxygenase domain containing protein 0.0008 0.0034 0.0034
Brugia malayi hypothetical protein 0.0008 0.0034 0.0034
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0065 0.0763 0.0925
Trypanosoma cruzi PAB1-binding protein , putative 0.0047 0.0534 0.0647
Trypanosoma brucei adenosine transporter 2 0.0096 0.1162 0.1406
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0024 0.0243 0.0289
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0065 0.0763 0.0922
Loa Loa (eye worm) hypothetical protein 0.0008 0.0034 0.0034
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0056 0.0065
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0065 0.0763 0.1066
Echinococcus multilocularis allatostatin A receptor 0.0024 0.0243 0.0237
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0468 0.5917 0.5914
Leishmania major nucleoside phosphatase, putative,guanosine diphosphatase, putative 0.0026 0.0271 0.0327
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0098 0.1187 0.1438
Schistosoma mansoni alpha-glucosidase 0.0136 0.1674 0.2032
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0392 0.0386
Leishmania major inosine-guanosine transporter;with=GeneDB:LinJ36_V3.2040 0.0096 0.1162 0.1412
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0065 0.0763 0.0925
Trypanosoma cruzi DNA/RNA non-specific endonuclease protein-like, putative 0.0008 0.0036 0.0041
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0024 0.0243 0.0237
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0047 0.0538 0.0745
Loa Loa (eye worm) Smad1 0.0022 0.0216 0.0256
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0007 0.0017 0.0011
Loa Loa (eye worm) doublecortin family protein 0.0008 0.0034 0.0034
Echinococcus multilocularis orexin receptor type 2 0.0024 0.0243 0.0237
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0763 0.1066
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0065 0.0763 0.0757
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.001 0.0056 0.0055
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0392 0.0474
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0185 0.164
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0065 0.0763 0.0928
Echinococcus granulosus pseudouridine metabolizing bifunctional protein 0.0074 0.0878 0.1062
Schistosoma mansoni hypothetical protein 0.0047 0.0532 0.0641
Brugia malayi RNA binding protein 0.0052 0.0596 0.0719
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0382 0.0522
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0096 0.1162 0.1406
Schistosoma mansoni cytochrome P450 0.0006 0.0008 0.0003
Toxoplasma gondii thioredoxin reductase 0.0019 0.0174 0.0212
Toxoplasma gondii hypothetical protein 0.003 0.0315 0.0384
Echinococcus multilocularis neuropeptide FF receptor 2 0.0024 0.0243 0.0237
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0096 0.1162 0.1638
Schistosoma mansoni hypothetical protein 0.0008 0.0034 0.0034
Brugia malayi beta-lactamase 0.0035 0.0381 0.0457
Trypanosoma cruzi nucleoside transporter 1, putative 0.0096 0.1162 0.1412
Echinococcus granulosus mixed lineage leukemia protein mll 0.0007 0.0029 0.0028
Trypanosoma brucei adenosine transporter 2, putative 0.0096 0.1162 0.1406
Echinococcus granulosus neuropeptide Y receptor 0.0024 0.0243 0.0289
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0013 0.0104 0.012
Mycobacterium ulcerans acyl-CoA synthetase 0.001 0.0063 0.0159
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0024 0.0243 0.0237
Toxoplasma gondii ABC1 family protein 0.0035 0.0381 0.0463
Echinococcus granulosus lipoxygenase domain containing protein 0.0008 0.0034 0.0034
Echinococcus granulosus sex peptide receptor 0.0024 0.0243 0.0289
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0056 0.0055
Schistosoma mansoni Smad4 0.0022 0.0216 0.0256
Brugia malayi G protein-coupled receptor 0.0024 0.0243 0.0289
Echinococcus granulosus g protein coupled receptor 0.0024 0.0243 0.0289
Loa Loa (eye worm) AMP-binding enzyme family protein 0.001 0.0063 0.0069
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Onchocerca volvulus 0.0024 0.0243 0.0289
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0007 0.0017 0.0014
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0023 0.0228 0.0637
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0185 0.024
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0013 0.0104 0.0099
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.0712 0.0866
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0381 0.0461
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0185 0.0513
Schistosoma mansoni hypothetical protein 0.0015 0.0129 0.015
Schistosoma mansoni neuropeptide receptor 0.0024 0.0243 0.0289
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0065 0.0763 0.0928
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0065 0.0763 0.1066
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0007 0.0017 0.0018
Toxoplasma gondii aldehyde dehydrogenase 0.0065 0.0767 0.0933
Schistosoma mansoni opsin-like receptor 0.0024 0.0243 0.0289
Onchocerca volvulus 0.0023 0.0228 0.0268
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0141 0.0387
Loa Loa (eye worm) inositol-1 0.0036 0.0392 0.047
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0382 0.0377
Loa Loa (eye worm) hypothetical protein 0.0035 0.0381 0.0457
Onchocerca volvulus 0.0024 0.0243 0.0289
Schistosoma mansoni loxhd1 0.0008 0.0034 0.0034
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0096 0.1162 0.1638
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Brugia malayi Pax transcription activation domain interacting protein 0.001 0.0056 0.0061
Schistosoma mansoni acetylcholinesterase 0.0023 0.0228 0.027
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.001 0.0063 0.0159
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0026 0.0271 0.0761
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.003 0.0315 0.2911
Loa Loa (eye worm) hypothetical protein 0.0018 0.0159 0.0187
Schistosoma mansoni ribokinase 0.0074 0.0878 0.1062
Brugia malayi sulfakinin receptor protein 0.0024 0.0243 0.0289
Schistosoma mansoni intermediate filament proteins 0.0026 0.0268 0.032
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0007 0.0021 0.0018
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0029 0.031 0.2967
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0006 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0026 0.0262 0.0312
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0029 0.031 0.0875
Entamoeba histolytica nucleoside transporter, putative 0.0553 0.7011 1
Echinococcus granulosus RUN 0.0008 0.0034 0.0034
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0243 0.0237
Loa Loa (eye worm) hypothetical protein 0.0065 0.0763 0.0922
Schistosoma mansoni biogenic amine receptor 0.0024 0.0243 0.0289
Onchocerca volvulus 0.0024 0.0243 0.0289
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0065 0.0763 0.0919
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0087 0.1042 0.1262
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.038 0.0456
Brugia malayi Cytochrome P450 family protein 0.003 0.0312 0.0373
Loa Loa (eye worm) melatonin receptor type 1A 0.0024 0.0243 0.0289
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.002 0.0005
Brugia malayi MH2 domain containing protein 0.0022 0.0216 0.0256
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0271 0.0327
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0271 0.142
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0065 0.0763 0.1066
Entamoeba histolytica hypothetical protein 0.0035 0.038 0.0514
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0381 0.052
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0024 0.0243 0.0289
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0024 0.0243 0.0289
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0065 0.0763 0.1066
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0065 0.0763 0.1066
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0392 0.0468
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0381 0.0457
Onchocerca volvulus 0.0024 0.0243 0.0289
Brugia malayi Cytochrome P450 family protein 0.0006 0.0008 0.0003
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0381 0.108
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0029 0.031 0.0304
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0065 0.0763 0.0757
Loa Loa (eye worm) hypothetical protein 0.0136 0.1675 0.2033
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Brugia malayi AMP-binding enzyme family protein 0.001 0.0063 0.0069
Trypanosoma brucei purine nucleoside transporter 0.0096 0.1162 0.1406
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0243 0.0289
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0096 0.1162 0.1638
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Leishmania major tagatose-6-phosphate kinase-like protein 0.0074 0.0878 0.1065
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0382 0.0517
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0065 0.0763 0.1066
Echinococcus granulosus carboxylesterase 5A 0.0136 0.1675 0.2033
Leishmania major cytochrome p450-like protein 0.0006 0.0008 0.0007
Echinococcus multilocularis dnaJ subfamily B 0.0428 0.5406 0.5404
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0381 0.052
Brugia malayi hypothetical protein 0.003 0.0321 0.0384
Brugia malayi Thioredoxin reductase 0.0019 0.0174 0.0206
Loa Loa (eye worm) hypothetical protein 0.0096 0.1162 0.1408
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0024 0.0243 0.0289
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0271 0.0357
Schistosoma mansoni lamin 0.0026 0.0268 0.032
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0007 0.0017 0.0018
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0382 0.0522
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0382 0.0522
Schistosoma mansoni hypothetical protein 0.0024 0.0243 0.0289
Onchocerca volvulus 0.0026 0.0271 0.0327
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0065 0.0763 0.0919
Schistosoma mansoni rotamase 0.0013 0.0104 0.0119
Brugia malayi Ribokinase 0.0074 0.0878 0.1062
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0013 0.0101 0.012
Toxoplasma gondii nucleoside transporter protein 0.0096 0.1162 0.1414
Echinococcus granulosus ectonucleoside triphosphate diphosphohydrolase 0.0017 0.0156 0.0183
Mycobacterium tuberculosis Conserved protein 0.0035 0.0381 0.108
Brugia malayi hypothetical protein 0.0024 0.0243 0.0289
Schistosoma mansoni neuropeptide F-like receptor 0.0024 0.0243 0.0289
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Brugia malayi Carboxylesterase family protein 0.0023 0.0228 0.027
Loa Loa (eye worm) hypothetical protein 0.0048 0.0552 0.0665
Onchocerca volvulus Huntingtin homolog 0.0119 0.1454 0.1962
Schistosoma mansoni guanosine-diphosphatase 0.0017 0.0156 0.0183
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Loa Loa (eye worm) hypothetical protein 0.001 0.0056 0.0061
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0007 0.0029 0.0023
Trichomonas vaginalis guanosine-diphosphatase, putative 0.0017 0.0156 0.0198
Giardia lamblia Replication factor C, subunit 1 0.001 0.0056 0.0055
Schistosoma mansoni chromosome transmission fidelity factor 0.001 0.0056 0.0061
Giardia lamblia hypothetical protein 0.0065 0.0763 0.1066
Echinococcus multilocularis G protein coupled receptor 139 0.0024 0.0243 0.0237
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0243 0.0289
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0043 0.0483 0.257
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0024 0.0243 0.0237
Leishmania major adenosine kinase, putative 0.0648 0.8219 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0243 0.0237
Plasmodium falciparum LCCL domain-containing protein 0.0008 0.0034 0.0166
Echinococcus granulosus equilibrative nucleoside transporter 0.0553 0.7011 0.8529
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0007 0.0021 0.0018
Trypanosoma cruzi nucleoside transporter 1, putative 0.0096 0.1162 0.1412
Schistosoma mansoni tar DNA-binding protein 0.0052 0.0596 0.0719
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0381 0.0375
Echinococcus multilocularis serotonin receptor 0.0024 0.0243 0.0237
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0013 0.01 0.0119
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0382 0.0522
Loa Loa (eye worm) hypothetical protein 0.0012 0.0089 0.0101
Loa Loa (eye worm) hypothetical protein 0.0119 0.1454 0.1764
Schistosoma mansoni inositol monophosphatase 0.0036 0.0392 0.047
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0065 0.0763 0.0928
Echinococcus multilocularis ribokinase 0.0074 0.0878 0.0872
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.002 0.0005
Echinococcus multilocularis adenosine kinase 0.0648 0.8219 0.8218
Schistosoma mansoni alpha-glucosidase 0.0136 0.1674 0.2032
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0007 0.0017 0.0018
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Loa Loa (eye worm) hypothetical protein 0.0013 0.0101 0.0116
Trypanosoma brucei endonuclease G, putative 0.0008 0.0036 0.0034
Loa Loa (eye worm) transcription factor SMAD2 0.0324 0.4082 0.4963
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0024 0.0243 0.0237
Loa Loa (eye worm) hypothetical protein 0.001 0.0056 0.0061
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0161 0.1988 0.2414
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0048 0.0545 0.2902
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0013 0.0104 0.012
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0382 0.0462
Schistosoma mansoni adenoreceptor 0.0024 0.0243 0.0289
Echinococcus granulosus neuropeptide s receptor 0.0024 0.0243 0.0289
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0243 0.0237
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Schistosoma mansoni alpha-1 adrenergic receptor 0.0024 0.0243 0.0289
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0065 0.0763 0.7274
Echinococcus multilocularis ectonucleoside triphosphate diphosphohydrolase 0.0017 0.0156 0.015
Brugia malayi mothers against decapentaplegic homolog 3 0.001 0.006 0.0066
Echinococcus granulosus fmrfamide receptor 0.0024 0.0243 0.0289
Brugia malayi Doublecortin family protein 0.0008 0.0034 0.0034
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0318 0.038
Brugia malayi acetyltransferase, GNAT family protein 0.0161 0.1988 0.2414
Echinococcus granulosus equilibrative nucleoside transporter 3 0.0553 0.7011 0.8529
Echinococcus granulosus TGF beta signal transducer SmadC 0.0022 0.0216 0.0256
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0065 0.0763 0.0919
Trypanosoma cruzi DNA/RNA non-specific endonuclease protein-like, putative 0.0008 0.0036 0.0041
Trypanosoma brucei adenosine transporter 2, putative 0.0096 0.1162 0.1406
Echinococcus granulosus peptide allatostatin:somatostatin 0.0024 0.0243 0.0289
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.002 0.0005
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0381 0.2016
Loa Loa (eye worm) hypothetical protein 0.0023 0.0228 0.027
Echinococcus granulosus mothers against decapentaplegic 6 0.001 0.006 0.0066
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0308 0.3873 0.5513
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0271 0.0327
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0065 0.0763 0.1066
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.001 0.0063 0.0074
Echinococcus multilocularis pseudouridine metabolizing bifunctional protein 0.0074 0.0878 0.0872
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0185 0.0223
Loa Loa (eye worm) acetylcholinesterase 1 0.0136 0.1675 0.2033
Brugia malayi hypothetical protein 0.0024 0.0243 0.0289
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0381 0.108
Echinococcus granulosus biogenic amine 5HT receptor 0.0024 0.0243 0.0289
Loa Loa (eye worm) hypothetical protein 0.0033 0.0356 0.0427
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0007 0.0021 0.0018
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0308 0.3873 0.5513
Entamoeba histolytica nucleoside transporter, putative 0.0096 0.1162 0.1633
Loa Loa (eye worm) hypothetical protein 0.0013 0.0095 0.0109
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0271 0.0761
Echinococcus granulosus biogenic amine 5HT receptor 0.0024 0.0243 0.0289
Trichomonas vaginalis esterase, putative 0.0035 0.0381 0.052
Echinococcus granulosus adenosine kinase 0.0648 0.8219 1
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0065 0.0763 0.0925
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0057 0.066 0.1889
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0344 0.0973
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0243 0.0237
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0024 0.0243 0.0237
Onchocerca volvulus 0.0024 0.0243 0.0289
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0065 0.0763 0.1066
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.002 0.0005
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0007 0.0017 0.0018
Loa Loa (eye worm) nuclear factor I 0.0012 0.009 0.0102
Echinococcus multilocularis carboxylesterase 5A 0.0136 0.1675 0.167
Echinococcus granulosus bloom syndrome protein 0.0008 0.0033 0.0033
Schistosoma mansoni histamine h1 receptor 0.0024 0.0243 0.0289
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0185 0.024
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0087 0.1042 0.5591
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0007 0.0021 0.0018
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0767 0.2198
Trichomonas vaginalis guanosine-diphosphatase, putative 0.0017 0.0156 0.0198
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0381 0.0457
Echinococcus granulosus intermediate filament protein 0.0026 0.0268 0.032
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.001 0.0063 0.0159
Brugia malayi Carboxylesterase family protein 0.0023 0.0228 0.027
Loa Loa (eye worm) hypothetical protein 0.0035 0.0381 0.0457
Schistosoma mansoni hypothetical protein 0.0033 0.0356 0.0427
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.001 0.0063 0.0074
Schistosoma mansoni hypothetical protein 0.0015 0.0129 0.015
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0468 0.5917 0.7197
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0098 0.1187 0.1182
Echinococcus multilocularis survival motor neuron protein 1 0.0229 0.2869 0.2865
Mycobacterium leprae Probable lipase LipE 0.0035 0.0381 0.2016
Trypanosoma cruzi nucleoside phosphatase, putative 0.0026 0.0271 0.0327
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0308 0.3873 0.5513
Schistosoma mansoni neuropeptide receptor 0.0024 0.0243 0.0289
Loa Loa (eye worm) hypothetical protein 0.0035 0.0381 0.0457
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Schistosoma mansoni neuroligin 3 (S09 family) 0.0023 0.0228 0.027
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0065 0.0763 0.0922
Trypanosoma brucei purine nucleoside transporter 0.0096 0.1162 0.1406
Trypanosoma brucei nucleoside diphosphatase, putative 0.0026 0.0271 0.032
Mycobacterium tuberculosis Probable reductase 0.0043 0.0483 0.1377
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0065 0.0763 0.0925
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0767 0.2198
Echinococcus granulosus lysosomal alpha glucosidase 0.0158 0.1956 0.2374
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0007 0.0021 0.0018
Loa Loa (eye worm) hypothetical protein 0.0013 0.0104 0.012
Echinococcus granulosus neuropeptide receptor 0.0024 0.0243 0.0289
Loa Loa (eye worm) hypothetical protein 0.001 0.0063 0.0069
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.003 0.0315 0.1662
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0468 0.5917 0.7197
Plasmodium vivax thioredoxin reductase, putative 0.0019 0.0174 0.1668
Schistosoma mansoni opsin-like receptor 0.0024 0.0243 0.0289
Entamoeba histolytica hypothetical protein 0.001 0.0056 0.005
Onchocerca volvulus 0.001 0.0063 0.004
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.001 0.0063 0.0159
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0159 0.1522
Loa Loa (eye worm) MH2 domain-containing protein 0.0022 0.0216 0.0256
Schistosoma mansoni neuropeptide receptor 0.0024 0.0243 0.0289
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0007 0.0021 0.0018
Loa Loa (eye worm) acetyltransferase 0.0161 0.1988 0.2414
Loa Loa (eye worm) hypothetical protein 0.0011 0.0077 0.0087
Schistosoma mansoni equilibrative nucleoside transporter 0.0096 0.1162 0.1408
Echinococcus multilocularis ectonucleotide 0.0011 0.0077 0.0072
Toxoplasma gondii kinase, pfkB family protein 0.0074 0.0878 0.1068
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0381 0.3649
Schistosoma mansoni endonuclease related 0.0008 0.0036 0.0037
Leishmania major cytochrome p450-like protein 0.0006 0.0008 0.0007
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0007 0.0017 0.0155
Onchocerca volvulus 0.0023 0.0228 0.0268
Trichomonas vaginalis maltase-glucoamylase, putative 0.0013 0.0101 0.012
Mycobacterium tuberculosis Probable oxidoreductase 0.0048 0.0545 0.1555
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0023 0.0228 0.027
Brugia malayi MH1 domain containing protein 0.0012 0.009 0.0102
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.003 0.0315 0.3021
Echinococcus multilocularis cpg binding protein 0.0032 0.034 0.0334
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0392 0.0474
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0024 0.0243 0.0289
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.001 0.0056 0.005
Echinococcus multilocularis musashi 0.0026 0.0268 0.0263
Schistosoma mansoni DNA ligase IV 0.001 0.0056 0.0061
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.001 0.0063 0.0296
Echinococcus granulosus lamin dm0 0.0026 0.0268 0.032
Schistosoma mansoni alpha glucosidase 0.0035 0.0382 0.0458
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.0051 0.0055
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0065 0.0763 0.7316
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.001 0.0063 0.0296
Loa Loa (eye worm) RecQ helicase 0.0008 0.0033 0.0033
Onchocerca volvulus 0.0091 0.1103 0.1477
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Brugia malayi AMP-binding enzyme family protein 0.001 0.0063 0.0069
Echinococcus granulosus neuropeptide FF receptor 2 0.0024 0.0243 0.0289
Trypanosoma cruzi nucleobase transporter, putative 0.0096 0.1162 0.1412
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.0271 0.0761
Trichomonas vaginalis adenosine diphosphatase, putative 0.0017 0.0156 0.0198
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0065 0.0763 0.0922
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0381 0.0454
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0243 0.0237
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.001 0.0056 0.0058
Loa Loa (eye worm) hypothetical protein 0.0023 0.0228 0.027
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0007 0.0017 0.0026
Loa Loa (eye worm) TYRA-2 protein 0.0024 0.0243 0.0289
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0065 0.0763 0.0928
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0065 0.0763 0.0922
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0096 0.1162 0.1638
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0392 0.0536
Brugia malayi hypothetical protein 0.0008 0.0034 0.0034
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0065 0.0767 0.0762
Brugia malayi intermediate filament protein 0.0026 0.0268 0.032
Schistosoma mansoni ATP-diphosphohydrolase 1 0.0017 0.0156 0.0183
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0129 0.015
Schistosoma mansoni rab6-interacting 0.0008 0.0034 0.0034
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0308 0.3873 0.5511
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0007 0.0017 0.0014
Schistosoma mansoni guanosine-diphosphatase 0.0017 0.0156 0.0183
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.001 0.0063 0.0159
Loa Loa (eye worm) hypothetical protein 0.0553 0.7011 0.8529
Schistosoma mansoni topbp1 0.001 0.0056 0.0061
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.001 0.0063 0.0069
Schistosoma mansoni lipoxygenase 0.0022 0.0215 0.0255
Entamoeba histolytica nucleoside transporter, putative 0.0096 0.1162 0.1633
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0129 0.015
Loa Loa (eye worm) hypothetical protein 0.0013 0.0104 0.012
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0382 0.0517
Leishmania major ribokinase, putative 0.0074 0.0878 0.1065
Brugia malayi Dopamine receptor protein 1 0.0024 0.0243 0.0289
Echinococcus granulosus neuropeptide receptor A26 0.0024 0.0243 0.0289
Brugia malayi Nucleoside-diphosphatase mig-23 0.0017 0.0156 0.0183
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0065 0.0763 0.0922
Leishmania major acetyl-CoA synthetase, putative 0.001 0.0063 0.0074
Echinococcus granulosus hypothetical protein 0.0024 0.0243 0.0289
Trypanosoma brucei nucleobase/nucleoside transporter 8.1 0.0096 0.1162 0.1406
Echinococcus multilocularis fmrfamide receptor 0.0024 0.0243 0.0237
Echinococcus multilocularis Smad4 0.0022 0.0216 0.0211
Trypanosoma brucei trypanothione reductase 0.0019 0.0174 0.0203
Echinococcus granulosus mothers against decapentaplegic 2 0.001 0.006 0.0066
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.001 0.0063 0.0159
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0065 0.0763 0.1066
Echinococcus granulosus neuropeptides capa receptor 0.0024 0.0243 0.0289
Brugia malayi Inositol-1 0.0036 0.0392 0.047
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0381 0.052
Giardia lamblia Histone acetyltransferase GCN5 0.0043 0.0487 0.0673
Toxoplasma gondii isocitrate dehydrogenase 0.0029 0.031 0.0377
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0381 0.0457
Plasmodium vivax phosphodiesterase gamma, putative 0.0065 0.0763 0.7316
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0029 0.031 0.0368
Echinococcus multilocularis g protein coupled receptor 0.0024 0.0243 0.0237
Giardia lamblia Hypothetical protein 0.0065 0.0763 0.1066
Brugia malayi hypothetical protein 0.0024 0.0243 0.0289
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0024 0.0243 0.0289
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0129 0.015
Loa Loa (eye worm) neuropeptide F receptor 0.0024 0.0243 0.0289
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0065 0.0763 0.7274
Leishmania major cytochrome p450-like protein 0.0006 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.001 0.0063 0.0069
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0024 0.0243 0.0289
Schistosoma mansoni BC026374 protein (S09 family) 0.0023 0.0228 0.027
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0007 0.0017 0.0018
Echinococcus multilocularis GPCR, family 2 0.0015 0.0129 0.0124
Echinococcus granulosus BC026374 protein S09 family 0.0023 0.0228 0.027
Schistosoma mansoni topbp1 0.001 0.0056 0.0061
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0024 0.0243 0.0237
Loa Loa (eye worm) TAR-binding protein 0.0052 0.0596 0.0719
Trichomonas vaginalis rotamase, putative 0.0013 0.0104 0.0124
Echinococcus multilocularis Endonuclease G 0.0008 0.0036 0.003
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.001 0.0063 0.0159
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0024 0.0243 0.0289
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0356 0.0427
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0065 0.0763 0.1066
Loa Loa (eye worm) hypothetical protein 0.001 0.006 0.0066
Mycobacterium ulcerans acyl-CoA synthetase 0.001 0.0063 0.0159
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0006 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.001 0.0056 0.0061
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0113 0.0131
Brugia malayi putative neuropeptide receptor 0.0024 0.0243 0.0289
Trypanosoma cruzi adenosine kinase, putative 0.0648 0.8219 1
Brugia malayi Tachykinin-like peptides receptor 99D 0.0024 0.0243 0.0289
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0065 0.0763 0.0757
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0024 0.0243 0.0289
Loa Loa (eye worm) hypothetical protein 0.001 0.0056 0.0061
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.0748 0.0904
Echinococcus multilocularis ectonucleoside triphosphate diphosphohydrolase 0.0017 0.0156 0.015
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0065 0.0763 0.1066
Schistosoma mansoni tar DNA-binding protein 0.0052 0.0596 0.0719
Echinococcus multilocularis ectonucleoside triphosphate diphosphohydrolase 0.0017 0.0156 0.015
Loa Loa (eye worm) hypothetical protein 0.0035 0.0381 0.0457
Onchocerca volvulus 0.0074 0.0878 0.1165
Trypanosoma brucei nucleoside transporter 1, putative 0.0096 0.1162 0.1406
Brugia malayi MH1 domain containing protein 0.0012 0.009 0.0102
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0007 0.0017 0.0155
Brugia malayi hypothetical protein 0.0074 0.0878 0.1062
Schistosoma mansoni amine GPCR 0.0024 0.0243 0.0289
Plasmodium falciparum nucleoside-diphosphatase, putative 0.0017 0.0156 0.1353
Loa Loa (eye worm) hypothetical protein 0.0023 0.0228 0.027
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0065 0.0763 0.0922
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0308 0.3873 0.5513
Onchocerca volvulus 0.0024 0.0243 0.0289
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0243 0.0289
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.001 0.0063 0.0159
Echinococcus multilocularis bloom syndrome protein 0.0008 0.0033 0.0027
Loa Loa (eye worm) thioredoxin reductase 0.0019 0.0174 0.0206
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.001 0.0063 0.0057
Plasmodium vivax replication factor C subunit 1, putative 0.001 0.0056 0.0527
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0392 0.3658
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0022 0.0216 0.0256
Echinococcus granulosus neuroligin 0.0023 0.0228 0.027
Brugia malayi Melatonin receptor type 1A 0.0024 0.0243 0.0289
Onchocerca volvulus 0.0024 0.0243 0.0289
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0532 0.6746 0.8206
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0048 0.0552 0.0665
Schistosoma mansoni hypothetical protein 0.0015 0.0129 0.015
Loa Loa (eye worm) hypothetical protein 0.0023 0.0228 0.027
Leishmania major nucleoside transporter 1, putative 0.0096 0.1162 0.1412
Trichomonas vaginalis ribokinase, putative 0.0074 0.0878 0.1231
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0048 0.0545 0.1555
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0024 0.0243 0.0289
Brugia malayi Carboxylesterase family protein 0.0023 0.0228 0.027
Echinococcus multilocularis thioredoxin glutathione reductase 0.0019 0.0174 0.0169
Echinococcus multilocularis fmrfamide receptor 0.0024 0.0243 0.0237
Loa Loa (eye worm) hypothetical protein 0.0012 0.009 0.0102
Onchocerca volvulus 0.0024 0.0243 0.0289
Giardia lamblia Ribokinase 0.0074 0.0878 0.1231
Loa Loa (eye worm) AMP-binding enzyme family protein 0.001 0.0063 0.0069
Trypanosoma cruzi nucleoside transporter 1, putative 0.0096 0.1162 0.1412
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0007 0.0017 0.0026
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0065 0.0763 0.1066
Echinococcus multilocularis neuropeptide s receptor 0.0024 0.0243 0.0237
Brugia malayi Dopamine receptor protein 2 0.0024 0.0243 0.0289
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0065 0.0763 0.1066
Schistosoma mansoni amine GPCR 0.0024 0.0243 0.0289
Brugia malayi Carboxylesterase family protein 0.0136 0.1675 0.2033
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0308 0.3873 0.5513
Leishmania major tagatose-6-phosphate kinase-like protein 0.0074 0.0878 0.1065
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0065 0.0763 0.1066
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0392 0.0477
Brugia malayi AMP-binding enzyme family protein 0.001 0.0063 0.0069
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0101 0.012
Trypanosoma brucei endonuclease G, putative 0.0008 0.0036 0.0034
Brugia malayi Probable ClpP-like protease 0.0087 0.1042 0.1262
Loa Loa (eye worm) G-protein coupled receptor 0.0024 0.0243 0.0289
Brugia malayi Carboxylesterase family protein 0.0136 0.1675 0.2033
Echinococcus granulosus para nitrobenzyl esterase 0.0023 0.0228 0.027
Brugia malayi hypothetical protein 0.0024 0.0243 0.0289
Mycobacterium tuberculosis Carboxylesterase LipT 0.0023 0.0228 0.0637
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0243 0.0289
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.0878 0.1231
Loa Loa (eye worm) hypothetical protein 0.001 0.0056 0.0061
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.001 0.0063 0.0296
Trichomonas vaginalis antibiotic synthetase, putative 0.001 0.0063 0.0065
Echinococcus multilocularis 0.0006 0.0008 0.0002
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.001 0.0063 0.0159
Onchocerca volvulus 0.0024 0.0243 0.0289
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0553 0.7011 1
Trypanosoma brucei glucosidase, putative 0.0035 0.0382 0.0456
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0065 0.0763 0.0928
Brugia malayi Serotonin receptor 0.0024 0.0243 0.0289
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0532 0.6746 0.6744
Leishmania major adenosine kinase-like protein 0.0074 0.0878 0.1065
Trypanosoma brucei adenosine transporter, putative 0.0096 0.1162 0.1406
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0024 0.0243 0.0289
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0024 0.0243 0.0289
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0243 0.0237
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0056 0.0055
Loa Loa (eye worm) cytochrome P450 family protein 0.003 0.0312 0.0373
Trypanosoma cruzi adenosine kinase, putative 0.0648 0.8219 1
Onchocerca volvulus 0.0029 0.0302 0.0371
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0011 0.0077 0.0072
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0007 0.0021 0.0018
Brugia malayi endonuclease G, mitochondrial precursor 0.0008 0.0036 0.0037
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0043 0.0483 0.1377
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.001 0.0063 0.006
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0381 0.052
Toxoplasma gondii propionate-CoA ligase 0.001 0.0063 0.0076
Trypanosoma cruzi hypothetical protein, conserved 0.0065 0.0763 0.0925
Schistosoma mansoni biogenic amine receptor 0.0024 0.0243 0.0289
Schistosoma mansoni biogenic amine (5HT) receptor 0.0024 0.0243 0.0289
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0129 0.0124
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0013 0.0101 0.0114
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0029 0.031 0.0304
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0065 0.0763 0.1066
Echinococcus granulosus Smad4 0.0022 0.0216 0.0256
Loa Loa (eye worm) hypothetical protein 0.0013 0.0104 0.012
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0065 0.0763 0.0928
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0553 0.7011 1
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.0767 0.0927
Onchocerca volvulus 0.0023 0.0228 0.0268
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0024 0.0243 0.0237
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0024 0.0243 0.0289
Schistosoma mansoni Smad4 0.001 0.006 0.0066
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0087 0.1042 1
Brugia malayi hypothetical protein 0.001 0.0056 0.0061
Mycobacterium ulcerans fructokinase, PfkB 0.0074 0.0878 0.2519
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0392 0.047
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.1187 0.1438
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0185 0.024
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0065 0.0763 0.7316
Echinococcus multilocularis g protein coupled receptor 0.0024 0.0243 0.0237
Echinococcus granulosus mothers against decapentaplegic 5 0.0022 0.0216 0.0256
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0011 0.0077 0.0087
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.1187 0.1438
Schistosoma mansoni biogenic amine (5HT) receptor 0.0024 0.0243 0.0289
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0021 0.0203 0.024
Onchocerca volvulus 0.0024 0.0243 0.0289
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0056 0.0055
Treponema pallidum fructose-bisphosphate aldolase 0.0308 0.3873 1
Brugia malayi TAR-binding protein 0.0052 0.0596 0.0719
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0382 0.0462
Leishmania major hypothetical protein, conserved 0.0047 0.0534 0.0647
Trypanosoma cruzi hypothetical protein, conserved 0.0065 0.0763 0.0925
Echinococcus granulosus neuropeptides capa receptor 0.0024 0.0243 0.0289
Schistosoma mansoni hypothetical protein 0.0006 0.0008 0.0003
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Trichomonas vaginalis adenosine/guanosine diphosphatase, putative 0.0017 0.0156 0.0198
Echinococcus multilocularis lamin 0.0026 0.0268 0.0263
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.0159 0.1388
Leishmania major hypothetical protein, conserved 0.0065 0.0763 0.0925
Echinococcus multilocularis peptidase Clp (S14 family) 0.0057 0.066 0.0655
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0065 0.0763 0.0922
Brugia malayi Adenosine kinase-like 0.0648 0.8219 1
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0065 0.0763 0.1066
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0026 0.0271 0.0761
Brugia malayi hypothetical protein 0.0024 0.0243 0.0289
Brugia malayi Calcitonin receptor-like protein seb-1 0.0048 0.0552 0.0665
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0065 0.0763 0.1066
Trypanosoma brucei adenosine transporter, putative 0.0096 0.1162 0.1406
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0007 0.0017 0.0018
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0243 0.0289
Toxoplasma gondii kinase, pfkB family protein 0.0648 0.8219 1
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0065 0.0763 0.0919
Trypanosoma cruzi nucleoside transporter-like, putative 0.0096 0.1162 0.1412
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0276 0.346 1
Schistosoma mansoni tar DNA-binding protein 0.0052 0.0596 0.0719
Brugia malayi hypothetical protein 0.0096 0.1162 0.1408
Mycobacterium ulcerans acyl-CoA synthetase 0.001 0.0063 0.0159
Chlamydia trachomatis DNA ligase 0.001 0.0056 0.0377
Echinococcus multilocularis lamin dm0 0.0026 0.0268 0.0263
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0024 0.0243 0.0289
Trypanosoma brucei nucleoside transporter 1, putative 0.0096 0.1162 0.1406
Echinococcus multilocularis somatostatin receptor 0.0024 0.0243 0.0237
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0065 0.0763 0.0922
Echinococcus granulosus 7tm_1 domain containing protein 0.0024 0.0243 0.0289
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0087 0.1042 0.2996
Trypanosoma cruzi ribokinase, putative 0.0074 0.0878 0.1065
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0087 0.1042 0.1268
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0065 0.0763 0.1066
Onchocerca volvulus 0.0026 0.0268 0.0324
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.001 0.0056 0.0055
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0023 0.0228 0.0222
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0065 0.0763 0.1066
Echinococcus granulosus nibrin 0.001 0.0056 0.0061
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0065 0.0763 0.1066
Schistosoma mansoni lamin 0.0026 0.0268 0.032
Echinococcus granulosus orexin receptor type 2 0.0024 0.0243 0.0289
Loa Loa (eye worm) hypothetical protein 0.0023 0.0228 0.027
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0243 0.0289
Schistosoma mansoni cpg binding protein 0.003 0.0318 0.038
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.001 0.0063 0.0159
Loa Loa (eye worm) hypothetical protein 0.0023 0.0228 0.027
Echinococcus granulosus Polycystic kidney disease protein 0.0008 0.0034 0.0034
Brugia malayi Cytochrome P450 family protein 0.0006 0.0008 0.0003
Schistosoma mansoni lipoxygenase 0.0008 0.0034 0.0034
Leishmania major ATP diphosphohydrolase 0.0026 0.0271 0.0327
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0007 0.0021 0.0018
Leishmania major DNA/RNA non-specific endonuclease-like protein 0.0008 0.0036 0.0041
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0065 0.0763 0.0928
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0065 0.0763 0.7274
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0024 0.0243 0.0289
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0024 0.0243 0.0289
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0159 0.1388
Trypanosoma cruzi nucleoside phosphatase, putative 0.0017 0.0156 0.0187
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0013 0.0104 0.012
Echinococcus granulosus peptidase Clp S14 family 0.0057 0.066 0.0797
Mycobacterium ulcerans hypothetical protein 0.0035 0.0381 0.108
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0392 0.1113
Echinococcus granulosus expressed protein 0.0013 0.0104 0.0119
Loa Loa (eye worm) hypothetical protein 0.0026 0.0271 0.0323
Echinococcus multilocularis para nitrobenzyl esterase 0.0023 0.0228 0.0222
Leishmania major nucleobase transporter 0.0096 0.1162 0.1412
Loa Loa (eye worm) neuropeptide F receptor 0.0024 0.0243 0.0289
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0381 0.0457
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0113 0.0131
Echinococcus multilocularis nibrin 0.001 0.0056 0.005
Mycobacterium ulcerans lipase LipD 0.0035 0.0381 0.108
Mycobacterium tuberculosis Ribokinase RbsK 0.0074 0.0878 0.2519
Brugia malayi isocitrate dehydrogenase 0.0029 0.031 0.037
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0185 0.0179
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.002 0.0005
Trypanosoma cruzi adenosine kinase, putative 0.0074 0.0878 0.1065
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0468 0.5917 0.7197
Echinococcus granulosus tachykinin peptides receptor 99D 0.0024 0.0243 0.0289
Brugia malayi G-protein coupled receptor 0.0024 0.0243 0.0289
Loa Loa (eye worm) hypothetical protein 0.0119 0.1454 0.1764
Giardia lamblia Hypothetical protein 0.0553 0.7011 1
Schistosoma mansoni neuropeptide F-like receptor 0.0024 0.0243 0.0289
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0271 0.0323
Schistosoma mansoni growth hormone secretagogue receptor 0.0024 0.0243 0.0289
Loa Loa (eye worm) cytochrome P450 0.0006 0.0008 0.0003
Leishmania major nucleoside transporter 1, putative 0.0096 0.1162 0.1412
Loa Loa (eye worm) glutathione reductase 0.0019 0.0174 0.0206
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0024 0.0243 0.0237
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0013 0.0104 0.012
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0382 0.0522
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0065 0.0763 0.1066
Echinococcus granulosus cytochrome P450 2K1 0.0006 0.0008 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0243 0.0237
Schistosoma mansoni smad1 5 8 and 0.0022 0.0216 0.0256
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.002 0.0005
Echinococcus multilocularis serotonin receptor 0.0024 0.0243 0.0237
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.001 0.0063 0.0074
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0381 0.108
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0065 0.0763 0.0922
Trypanosoma brucei adenosine kinase, putative 0.0648 0.8219 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0271 0.0323
Trichomonas vaginalis guanosine-diphosphatase, putative 0.0017 0.0156 0.0198
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0024 0.0243 0.0289
Mycobacterium tuberculosis Probable dehydrogenase 0.0043 0.0483 0.1377
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.001 0.0063 0.0159
Schistosoma mansoni peptidase Clp (S14 family) 0.0087 0.1042 0.1262
Brugia malayi Isocitrate dehydrogenase 0.0029 0.031 0.037
Trypanosoma cruzi hypothetical protein, conserved 0.0065 0.0763 0.0925
Onchocerca volvulus 0.0024 0.0243 0.0289
Leishmania major acetyl-CoA synthetase, putative 0.001 0.0063 0.0074
Schistosoma mansoni protein kinase 0.0096 0.1162 0.1408
Schistosoma mansoni amine GPCR 0.0024 0.0243 0.0289
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0382 0.0522
Trypanosoma cruzi cytochrome P450, putative 0.0006 0.0008 0.0007
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0065 0.0763 0.1066
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0095 0.0109
Echinococcus multilocularis neuropeptide receptor A26 0.0024 0.0243 0.0237
Mycobacterium leprae Probable adenosine kinase adk 0.0074 0.0878 0.4701
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0553 0.7011 1
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0065 0.0763 0.1066
Echinococcus multilocularis smad 0.0022 0.0216 0.0211
Toxoplasma gondii cytochrome p450 superfamily protein 0.0006 0.0008 0.001
Mycobacterium ulcerans acyl-CoA synthetase 0.001 0.0063 0.0159
Echinococcus granulosus tm gpcr rhodopsin 0.0024 0.0243 0.0289
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0024 0.0243 0.0237
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0024 0.0243 0.0289
Loa Loa (eye worm) hypothetical protein 0.0648 0.8219 1
Mycobacterium ulcerans carboxylesterase, LipT 0.0023 0.0228 0.0637
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0065 0.0763 0.0928
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0095 0.0089
Trypanosoma brucei nucleoside phosphatase, putative 0.0026 0.0271 0.032
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0007 0.0021 0.0039
Schistosoma mansoni hypothetical protein 0.0024 0.0243 0.0289
Loa Loa (eye worm) hypothetical protein 0.0229 0.2869 0.3486
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0029 0.031 0.0374
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0268 0.032
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0065 0.0763 0.0757
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0141 0.0387
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0007 0.0029 0.0023
Trypanosoma brucei adenosine transporter 2, putative 0.0096 0.1162 0.1406
Brugia malayi CXXC zinc finger family protein 0.003 0.0318 0.038
Schistosoma mansoni tar DNA-binding protein 0.0052 0.0596 0.0719
Echinococcus granulosus neuropeptide receptor 0.0024 0.0243 0.0289
Echinococcus multilocularis tar DNA binding protein 0.0052 0.0596 0.0591
Trichomonas vaginalis replication factor C large subunit, putative 0.001 0.0056 0.0055
Echinococcus granulosus tm gpcr rhodopsin 0.0024 0.0243 0.0289
Trypanosoma brucei ribokinase, putative 0.0074 0.0878 0.1059
Echinococcus granulosus cpg binding protein 0.0032 0.034 0.0407
Onchocerca volvulus Neuropeptide F receptor homolog 0.0024 0.0243 0.0289
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0087 0.1042 1
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0013 0.0101 0.0092
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.001 0.0063 0.0159
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0065 0.0763 0.1066
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0065 0.0763 0.0919
Schistosoma mansoni hypothetical protein 0.0024 0.0243 0.0289
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0065 0.0763 0.1066
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0382 0.0458
Schistosoma mansoni hypothetical protein 0.0035 0.038 0.0456
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0065 0.0763 0.0922
Loa Loa (eye worm) hypothetical protein 0.0018 0.0159 0.0187
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0047 0.0538 0.0654
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0065 0.0763 0.0922
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0156 0.0198
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Brugia malayi MH2 domain containing protein 0.0324 0.4082 0.4963
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0065 0.0763 0.0928
Toxoplasma gondii peptidylprolyl isomerase 0.0013 0.01 0.0121
Loa Loa (eye worm) thrombospondin type 1 domain-containing protein 0.0029 0.0302 0.0361
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0185 0.0218
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0098 0.1187 0.1438
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.001 0.0056 0.0377
Schistosoma mansoni amine GPCR 0.0024 0.0243 0.0289
Brugia malayi hypothetical protein 0.0024 0.0243 0.0289
Onchocerca volvulus 0.0024 0.0243 0.0289
Trichomonas vaginalis rotamase, putative 0.0013 0.01 0.0118
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0065 0.0763 0.0925
Plasmodium falciparum ataxin-2 like protein, putative 0.0047 0.0534 0.5043
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0243 0.0289
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Entamoeba histolytica tagatose-6-phosphate kinase, putative 0.0074 0.0878 0.1226
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.001 0.0063 0.0159
Schistosoma mansoni myosin xvIII 0.0024 0.0243 0.0289
Echinococcus multilocularis lipoxygenase domain containing protein 0.0008 0.0034 0.0028
Echinococcus granulosus g protein coupled receptor 0.0024 0.0243 0.0289
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.002 0.0005
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0013 0.01 0.0119
Echinococcus granulosus serotonin receptor 0.0024 0.0243 0.0289
Onchocerca volvulus 0.0026 0.0268 0.0324
Schistosoma mansoni rab6-interacting 0.0008 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0532 0.6746 0.8206
Echinococcus granulosus replication factor c subunit 1 0.001 0.0056 0.0061
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0271 0.0357
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0065 0.0763 0.1066
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0029 0.031 0.0304
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0013 0.0104 0.0099
Brugia malayi follicle stimulating hormone receptor 0.0024 0.0243 0.0289
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0013 0.0104 0.0099
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0392 0.0474
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0065 0.0763 0.1066
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0043 0.0483 0.1377
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0065 0.0763 0.1066
Trichomonas vaginalis spcc417.12 protein, putative 0.0023 0.0228 0.0301
Loa Loa (eye worm) oxidoreductase 0.001 0.0063 0.0069
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0052 0.0057
Mycobacterium ulcerans acyl-CoA synthetase 0.001 0.0063 0.0159
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Trypanosoma cruzi adenosine kinase, putative 0.0074 0.0878 0.1065
Schistosoma mansoni hypothetical protein 0.0021 0.0203 0.024
Trypanosoma brucei adenosine transporter 2, putative 0.0096 0.1162 0.1406
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0065 0.0763 0.1066
Onchocerca volvulus 0.0013 0.0104 0.0097
Loa Loa (eye worm) hypothetical protein 0.0026 0.0268 0.032
Treponema pallidum DNA ligase (lig) 0.001 0.0056 0.01
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0243 0.0289
Brugia malayi Thrombospondin type 1 domain containing protein 0.0029 0.0302 0.0361
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0013 0.0104 0.012
Echinococcus granulosus GPCR family 2 0.0015 0.0129 0.015
Schistosoma mansoni amine GPCR 0.0024 0.0243 0.0289
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.002 0.0005
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.001 0.0056 0.0061
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0243 0.0289
Echinococcus granulosus somatostatin receptor 0.0024 0.0243 0.0289
Schistosoma mansoni hypothetical protein 0.0024 0.0243 0.0289
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0129 0.015
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0065 0.0763 0.1066
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0007 0.0017 0.0018
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0065 0.0763 0.0928
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0271 0.0323
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0065 0.0763 0.0922
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.001 0.0056 0.0065
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0065 0.0763 0.1066
Trypanosoma cruzi PAB1-binding protein , putative 0.0047 0.0534 0.0647
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0271 0.0323
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0185 0.0513
Trypanosoma cruzi trypanothione reductase, putative 0.0007 0.0017 0.0018
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0052 0.0047
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Trypanosoma cruzi hypothetical protein, conserved 0.0065 0.0763 0.0925
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.001 0.0056 0.0068
Entamoeba histolytica acyl-coA synthetase, putative 0.0026 0.0271 0.0357
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0007 0.0017 0.0026
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0065 0.0763 0.0757
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0271 0.142
Echinococcus multilocularis mothers against decapentaplegic 6 0.001 0.006 0.0054
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0013 0.0104 0.0119
Loa Loa (eye worm) cytochrome P450 family protein 0.0006 0.0008 0.0003
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0382 0.0522
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0065 0.0763 0.1066
Toxoplasma gondii Nucleoside-diphosphatase 0.0017 0.0156 0.0189
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.002 0.0005
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0024 0.0243 0.0289
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0381 0.0461
Brugia malayi Glycosyl hydrolases family 31 protein 0.0013 0.0101 0.0116
Brugia malayi topoisomerase 0.001 0.0056 0.0061
Mycobacterium ulcerans acyl-CoA synthetase 0.001 0.0063 0.0159
Plasmodium vivax multidomain scavenger receptor, putative 0.0008 0.0034 0.0318
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0065 0.0763 0.0928
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0382 0.0458
Loa Loa (eye worm) hypothetical protein 0.0007 0.0021 0.0018
Loa Loa (eye worm) hypothetical protein 0.0065 0.0763 0.0922
Echinococcus granulosus G protein coupled receptor 139 0.0024 0.0243 0.0289
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0065 0.0763 0.0922
Mycobacterium tuberculosis Conserved protein 0.0035 0.0381 0.108
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0023 0.0228 0.027
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0024 0.0243 0.0289
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0098 0.1187 0.1438
Trichomonas vaginalis DNA helicase recq, putative 0.0008 0.0033 0.0023
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0029 0.031 0.2857
Brugia malayi G-protein coupled receptor 0.0024 0.0243 0.0289
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.002 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.002 0.0005
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0065 0.0763 0.7316
Loa Loa (eye worm) hypothetical protein 0.0024 0.0243 0.0289
Loa Loa (eye worm) hypothetical protein 0.0065 0.0763 0.0922
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.001 0.0063 0.0074
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0013 0.01 0.0119
Brugia malayi putative neuropeptide receptor NPR1 0.0024 0.0243 0.0289
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0024 0.0243 0.0289
Plasmodium vivax glutathione reductase, putative 0.0019 0.0174 0.1668
Loa Loa (eye worm) hypothetical protein 0.0553 0.7011 0.8529
Loa Loa (eye worm) carboxylesterase 0.0136 0.1675 0.2033
Echinococcus granulosus dnaJ subfamily B 0.0428 0.5406 0.6575
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0007 0.0017 0.0011
Brugia malayi acetyl-Coenzyme A synthetase 2 0.001 0.0063 0.0069
Echinococcus granulosus ectonucleotide 0.0011 0.0077 0.0087
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0101 0.012
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0271 0.0327
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0013 0.01 0.0113
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0392 0.0536

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 440 nM Growth inhibition of human PC3 cells ChEMBL. 21761939
MIC (functional) = 1.25 ug ml-1 Antifungal activity against Candida albicans after 24 hrs by NCCLS M27-P broth macrodilution method ChEMBL. 21761939
MIC (functional) = 2.5 ug ml-1 Antifungal activity against Candida albicans harboring heterozygous deletion of PRE4/orf19.4230 after 24 hrs by NCCLS M27-P broth macrodilution method ChEMBL. 21761939
MIC (functional) = 2.5 ug ml-1 Antifungal activity against Candida albicans harboring heterozygous deletion of orf19.5378/SCL1 after 24 hrs by NCCLS M27-P broth macrodilution method ChEMBL. 21761939
MIC (functional) = 2.5 ug ml-1 Antifungal activity against Candida albicans harboring heterozygous deletion of orf19.3168/RPN8 after 24 hrs by NCCLS M27-P broth macrodilution method ChEMBL. 21761939
MIC (functional) = 2.5 ug ml-1 Antifungal activity against Candida albicans harboring heterozygous deletion of orf19.4088/NUP188 after 24 hrs by NCCLS M27-P broth macrodilution method ChEMBL. 21761939
MIC (functional) = 4 ug ml-1 Antifungal activity against Candida albicans 2323 after 24 hrs by NCCLS M27-P broth macrodilution method ChEMBL. 21761939

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 21761939

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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