Detailed information for compound 1648287

Basic information

Technical information
  • TDR Targets ID: 1648287
  • Name: (4R)-1-furan-3-yl-4-hydroxypentan-1-one
  • MW: 168.19 | Formula: C9H12O3
  • H donors: 1 H acceptors: 2 LogP: 0.71 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: C[C@H](CCC(=O)c1cocc1)O
  • InChi: 1S/C9H12O3/c1-7(10)2-3-9(11)8-4-5-12-6-8/h4-7,10H,2-3H2,1H3/t7-/m1/s1
  • InChiKey: RJYQLMILDVERHH-SSDOTTSWSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (4R)-1-(3-furyl)-4-hydroxy-pentan-1-one
  • (4R)-1-(3-furyl)-4-hydroxypentan-1-one
  • (4R)-1-furan-3-yl-4-hydroxy-pentan-1-one
  • NSC644433
  • NCIMech_000305
  • NCI60_015057
  • (4(R)-(-)-Ipomeanol)
  • 1-(3-Furyl)-4(R)-(-)-hydroxy-1-pentanone

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0032 0.0024 0.0024
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0065 0.0065
Plasmodium falciparum JmjC domain-containing protein, putative 0.0032 0.0024 0.022
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0031 0.0031
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0061 0.0086 0.0086
Echinococcus multilocularis L aminoadipate semialdehyde 0.009 0.0149 0.0149
Echinococcus multilocularis Niemann Pick C1 protein 0.0206 0.0398 0.0398
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0312 0.0626 0.0828
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.005 0.0062 0.11
Giardia lamblia 20S proteasome alpha subunit 3 0.0055 0.0074 0.0074
Brugia malayi nuclear receptor NHR-88 0.0032 0.0024 0.0024
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0027 0.0012 0.0012
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0031 0.0031
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0034 0.0034
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0032 0.0024 0.0019
Giardia lamblia 20S proteasome alpha subunit 4 0.0055 0.0074 0.0074
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0332 0.067 0.067
Echinococcus granulosus Proteasome subunit alpha type 7 0.0055 0.0074 0.0074
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0312 0.0626 0.0828
Schistosoma mansoni transient receptor potential channel 0.0108 0.0188 0.0188
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0135 0.0246 0.3578
Brugia malayi Muscleblind-like protein 0.0145 0.0266 0.0266
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0032 0.0024 0.0024
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0068 0.0101 0.0101
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0055 0.0074 0.097
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0079 0.0125 0.1743
Brugia malayi jmjC domain containing protein 0.0032 0.0024 0.0024
Loa Loa (eye worm) phosphatidylinositol 3 0.0063 0.009 0.009
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0034 0.0547
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0135 0.0246 0.0246
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0039 0.0039 0.0039
Entamoeba histolytica hypothetical protein 0.0147 0.0271 0.0271
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0055 0.0074 0.0074
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0032 0.0024 0.0024
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0027 0.0012 0.0012
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0032 0.0024 0.0024
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0039 0.0039
Leishmania major proteasome beta 3 subunit, putative 0.0055 0.0074 0.0074
Onchocerca volvulus Notchless protein homolog 0.0055 0.0074 0.0681
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0027 0.0013 0.0062
Schistosoma mansoni aldehyde dehydrogenase 0.0189 0.0361 0.0361
Schistosoma mansoni retinoic acid receptor RXR 0.0032 0.0024 0.0024
Loa Loa (eye worm) phosphatidylinositol 3 0.0312 0.0626 0.0626
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0031 0.0031
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0312 0.0626 0.0626
Echinococcus granulosus neuropeptide receptor A26 0.1446 0.3069 0.3069
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0121 0.0215 0.344
Trichomonas vaginalis bromodomain-containing protein, putative 0.0044 0.0049 0.0049
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0135 0.0246 0.0246
Plasmodium falciparum proteasome subunit beta type-5 0.0281 0.0559 0.8324
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0034 0.0034
Brugia malayi intermediate filament protein 0.0028 0.0014 0.0014
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0055 0.0074 0.0074
Schistosoma mansoni hypothetical protein 0.0023 0.0004 0.0004
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0055 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0037 0.0035 0.0035
Brugia malayi glutaminase DH11.1 0.028 0.0558 0.0558
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0032 0.0024 0.0024
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0031 0.0031
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0055 0.0074 0.0074
Mycobacterium tuberculosis Probable dehydrogenase 0.0109 0.0189 0.3022
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0188 0.036 0.036
Echinococcus multilocularis Niemann Pick C1 protein 0.0294 0.0588 0.0588
Echinococcus granulosus Niemann Pick C1 protein 0.0206 0.0398 0.0398
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0027 0.0012 0.0012
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0218 0.0425 0.0425
Schistosoma mansoni voltage-gated potassium channel 0.0027 0.0012 0.0012
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0312 0.0626 0.0626
Trichomonas vaginalis conserved hypothetical protein 0.0122 0.0217 0.0217
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0374 0.076 0.076
Onchocerca volvulus 0.0036 0.0031 0.0271
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0281 0.0559 0.0559
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0332 0.067 0.067
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0032 0.0024 0.0024
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0036 0.0036
Echinococcus multilocularis ecdysone induced protein 78C 0.0032 0.0024 0.0024
Trypanosoma cruzi hypothetical protein, conserved 0.0095 0.016 0.016
Schistosoma mansoni tyrosine kinase 0.0226 0.0442 0.0442
Plasmodium vivax acyl-CoA synthetase, putative 0.0037 0.0035 0.0379
Plasmodium falciparum acyl-CoA synthetase 0.0037 0.0035 0.0379
Schistosoma mansoni coup transcription factor 0.0032 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0108 0.0188 0.0188
Echinococcus granulosus L aminoadipate semialdehyde 0.009 0.0149 0.0149
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0027 0.0013 0.0058
Echinococcus granulosus geminin 0.0523 0.108 0.108
Trichomonas vaginalis PIKK family atypical protein kinase 0.372 0.7964 0.7964
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0121 0.0216 0.0216
Brugia malayi beta-lactamase 0.0037 0.0034 0.0034
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.4666 1 1
Entamoeba histolytica hypothetical protein 0.0036 0.0031 0.0031
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0031 0.0031
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0063 0.009 0.009
Entamoeba histolytica hypothetical protein 0.0469 0.0964 0.0964
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0032 0.0024 0.0019
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0036 0.0031 0.0031
Brugia malayi glutathione reductase 0.0048 0.0058 0.0058
Trichomonas vaginalis esterase, putative 0.0037 0.0034 0.0034
Trichomonas vaginalis chromobox protein, putative 0.0217 0.0423 0.0423
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.1647 0.35 0.35
Trichomonas vaginalis PIKK family atypical protein kinase 0.372 0.7964 0.7964
Leishmania major phosphatidylinositol kinase related protein, putative 0.0312 0.0626 0.0626
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0024 0.0024
Schistosoma mansoni steroid hormone receptor ad4bp 0.0032 0.0024 0.0024
Brugia malayi Glycosyl hydrolases family 31 protein 0.0039 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.059 0.1225 0.1225
Onchocerca volvulus 0.0037 0.0034 0.0298
Leishmania major proteasome beta-1 subunit, putative 0.0055 0.0074 0.0074
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0055 0.0074 0.097
Giardia lamblia Kinase, PLK 0.0199 0.0384 0.0384
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0079 0.0125 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0039 0.0039
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.0116 0.0206 0.0206
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0039 0.0039
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0027 0.0012 0.0012
Echinococcus multilocularis lysine specific demethylase 6a 0.0032 0.0024 0.0024
Echinococcus multilocularis voltage gated potassium channel 0.0038 0.0036 0.0036
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0218 0.0425 0.0425
Echinococcus multilocularis short transient receptor potential channel 6 0.0074 0.0115 0.0115
Echinococcus granulosus subfamily T1A non peptidase ue 0.0055 0.0074 0.0074
Entamoeba histolytica serine/threonine protein kinase, putative 0.0199 0.0384 0.0384
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.4666 1 1
Entamoeba histolytica hypothetical protein 0.0312 0.0626 0.0626
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0116 0.0206 0.0206
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0199 0.0384 0.0384
Echinococcus multilocularis proteasome subunit alpha type 2 0.0055 0.0074 0.0074
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0037 0.0035 0.0618
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0031 0.0031
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.4666 1 1
Echinococcus granulosus Protein patched homolog 1 0.0088 0.0145 0.0145
Brugia malayi Valyl-tRNA synthetase 0.0036 0.0031 0.0031
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0055 0.0074 0.0074
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0055 0.0074 0.097
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0052 0.0066 0.0919
Echinococcus granulosus FTZ F1 alpha 0.0032 0.0024 0.0024
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0218 0.0425 0.0425
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0121 0.0214 0.0214
Brugia malayi Associated with TFs and helicases family protein 0.0036 0.0031 0.0031
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0281 0.0561 0.0561
Echinococcus granulosus proteasome subunit beta type 7 0.0055 0.0074 0.0074
Trichomonas vaginalis PIKK family atypical protein kinase 0.3028 0.6474 0.6474
Schistosoma mansoni lamin 0.0028 0.0014 0.0014
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0063 0.0091 0.0109
Echinococcus granulosus citrate lyase subunit beta protein 0.0025 0.0009 0.0009
Leishmania major 4-coumarate:coa ligase-like protein 0.005 0.0062 0.0062
Onchocerca volvulus 0.0102 0.0174 0.1658
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0055 0.0074 0.0074
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.005 0.0062 0.0844
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0036 0.0036
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0065 0.0075
Toxoplasma gondii non-specific serine/threonine protein kinase 0.1004 0.2116 0.2831
Schistosoma mansoni chromobox protein 0.0036 0.0031 0.0031
Mycobacterium ulcerans proteasome PrcB 0.0281 0.0559 1
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.001 0.001
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0034 0.0547
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0109 0.0189 0.3022
Loa Loa (eye worm) hypothetical protein 0.0052 0.0066 0.0066
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0025 0.001 0.0153
Echinococcus granulosus intermediate filament protein 0.0028 0.0014 0.0014
Echinococcus multilocularis transient receptor potential gamma protein 0.0108 0.0188 0.0188
Mycobacterium tuberculosis Probable reductase 0.0109 0.0189 0.3022
Echinococcus granulosus voltage gated potassium channel 0.0038 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0032 0.0024 0.0024
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0079 0.0125 0.1743
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0116 0.0206 0.0206
Plasmodium vivax proteasome subunit beta type-3, putative 0.0055 0.0074 0.097
Trichomonas vaginalis PIKK family atypical protein kinase 0.3481 0.745 0.745
Leishmania major hypothetical protein, conserved 0.0218 0.0425 0.0425
Trypanosoma brucei proteasome beta 6 subunit 0.0218 0.0425 0.0425
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0312 0.0626 0.0626
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0036 0.0036
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.003 0.0483
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0312 0.0626 0.0626
Entamoeba histolytica hypothetical protein 0.0147 0.0271 0.0271
Brugia malayi proteasome subunit alpha type 3 0.0055 0.0074 0.0074
Brugia malayi Proteasome A-type and B-type family protein 0.0055 0.0074 0.0074
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0034 0.0612
Loa Loa (eye worm) hypothetical protein 0.0032 0.0024 0.0024
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0055 0.0074 0.097
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0055 0.0074 0.0074
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0055 0.0074 0.0074
Schistosoma mansoni hypothetical protein 0.0085 0.0138 0.0138
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0055 0.0074 0.097
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0055 0.0074 0.1177
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0181 0.0344 0.0344
Echinococcus multilocularis muscleblind protein 0.0145 0.0266 0.0266
Echinococcus granulosus lysine specific demethylase 5A 0.0121 0.0214 0.0214
Loa Loa (eye worm) heterochromatin protein 1 0.0217 0.0423 0.0423
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.4666 1 1
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0062 0.11
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0031 0.0031
Entamoeba histolytica acyl-CoA synthetase, putative 0.005 0.0062 0.0062
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0027 0.0012 0.0012
Echinococcus multilocularis thyroid hormone receptor alpha 0.0032 0.0024 0.0024
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0065 0.0065
Schistosoma mansoni immunophilin 0.01 0.0171 0.0171
Giardia lamblia Proteasome subunit beta type 4 precursor 0.0055 0.0074 0.0074
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0027 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0038 0.0036 0.0036
Trichomonas vaginalis fk506-binding protein, putative 0.0116 0.0206 0.0206
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0446 0.0916 0.0916
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0027 0.0012 0.0012
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0438 0.0899 0.0899
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0055 0.0074 0.0074
Mycobacterium leprae Probable lipase LipE 0.0037 0.0034 0.04
Trichomonas vaginalis PIKK family atypical protein kinase 0.4666 1 1
Echinococcus multilocularis tumor protein p63 0.0696 0.1452 0.1452
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0025 0.0009 0.016
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0055 0.0074 0.0074
Echinococcus granulosus hyperpolarization activated cyclic 0.0027 0.0012 0.0012
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0031 0.0031
Echinococcus multilocularis phd:f box containing protein 0.0032 0.0024 0.0024
Giardia lamblia Proteasome subunit beta type 2 0.0135 0.0246 0.0246
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0312 0.0626 0.0626
Trichomonas vaginalis glutaminase, putative 0.028 0.0558 0.0558
Plasmodium falciparum heterochromatin protein 1 0.0036 0.0031 0.0332
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0055 0.0074 0.0074
Trichomonas vaginalis PIKK family atypical protein kinase 0.1253 0.2653 0.2653
Trichomonas vaginalis chromobox protein, putative 0.0131 0.0237 0.0237
Echinococcus granulosus proteasome subunit alpha type 6 0.0055 0.0074 0.0074
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0189 0.0361 0.0361
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0032 0.0024 0.0024
Trypanosoma cruzi polo-like protein kinase, putative 0.0199 0.0384 0.0384
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0135 0.0246 0.0246
Echinococcus granulosus Niemann Pick C1 protein 0.0294 0.0588 0.0588
Giardia lamblia Proteasome subunit beta type 7 precursor 0.0055 0.0074 0.0074
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0147 0.0271 0.0271
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0055 0.0074 0.0074
Schistosoma mansoni hypothetical protein 0.0085 0.0138 0.0138
Schistosoma mansoni transient receptor potential channel 0.0074 0.0115 0.0115
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0332 0.067 0.067
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0055 0.0074 0.0074
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0332 0.067 0.067
Trichomonas vaginalis sucrase-isomaltase, putative 0.0039 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0035 0.0031 0.0031
Echinococcus granulosus Chromo domain 0.0036 0.0031 0.0031
Brugia malayi CHD4 protein 0.0036 0.0031 0.0031
Schistosoma mansoni hypothetical protein 0.0692 0.1445 0.1445
Trichomonas vaginalis PIKK family atypical protein kinase 0.3481 0.745 0.745
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0055 0.0074 0.0074
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0055 0.0074 0.0074
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0032 0.0024 0.0024
Brugia malayi beta-lactamase family protein 0.0037 0.0034 0.0034
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0374 0.076 0.076
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0135 0.0246 0.0246
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0031 0.0332
Plasmodium vivax JmjC domain containing protein 0.0032 0.0024 0.022
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.0024 0.0024
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0034 0.0034
Entamoeba histolytica acyl-CoA synthetase, putative 0.005 0.0062 0.0062
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0116 0.0206 0.0206
Loa Loa (eye worm) glutaminase 2 0.028 0.0558 0.0558
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0055 0.0074 0.0074
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0312 0.0626 0.0626
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.0384 0.0384
Schistosoma mansoni hypothetical protein 0.0036 0.0031 0.0031
Brugia malayi Glycosyl hydrolases family 31 protein 0.0177 0.0336 0.0336
Brugia malayi Thioredoxin reductase 0.0048 0.0058 0.0058
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0692 0.1445 0.1445
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0902 0.1896 0.1896
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.058 0.1203 0.1203
Trichomonas vaginalis rotamase, putative 0.0035 0.0029 0.0029
Plasmodium vivax SET domain protein, putative 0.0063 0.0091 0.1227
Trichomonas vaginalis PIKK family atypical protein kinase 0.2778 0.5936 0.5936
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0312 0.0626 0.9327
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0055 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0079 0.0125 0.0125
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0036 0.0031 0.0031
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0135 0.0246 0.0246
Echinococcus multilocularis lysosomal alpha glucosidase 0.0177 0.0336 0.0336
Echinococcus multilocularis lamin 0.0028 0.0014 0.0014
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.005 0.0062 0.11
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0034 0.0028 0.0028
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0079 0.0125 0.2229
Trichomonas vaginalis chromobox protein, putative 0.0131 0.0237 0.0237
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0189 0.0361 0.0361
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0511 0.1054 0.1054
Trichomonas vaginalis PIKK family atypical protein kinase 0.0312 0.0626 0.0626
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.0055 0.0074 0.0074
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0281 0.0559 0.0559
Echinococcus granulosus Proteasome subunit alpha beta 0.0055 0.0074 0.0074
Plasmodium vivax proteasome subunit beta type-1, putative 0.0218 0.0425 0.6283
Leishmania major phosphatidylinositol 3-related kinase, putative 0.1605 0.3411 0.3411
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0068 0.0101 0.0101
Echinococcus multilocularis lysine specific demethylase 5A 0.0121 0.0214 0.0214
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0058 0.0058
Echinococcus granulosus TRP transient receptor potential channel 0.0045 0.0052 0.0052
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0902 0.1896 0.1896
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.1647 0.35 0.35
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0055 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.1004 0.2116 0.2116
Brugia malayi proteasome subunit beta type 2 0.0135 0.0246 0.0246
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.4666 1 1
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0055 0.0074 0.0074
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0036 0.0031 0.0031
Trypanosoma cruzi polo-like protein kinase, putative 0.0199 0.0384 0.0384
Onchocerca volvulus 0.0037 0.0034 0.0298
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0312 0.0626 0.0626
Loa Loa (eye worm) hypothetical protein 0.0028 0.0014 0.0014
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0034 0.04
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0068 0.0101 0.0101
Trypanosoma cruzi hypothetical protein, conserved 0.0218 0.0425 0.0425
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0312 0.0626 0.0626
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0055 0.0074 0.0074
Trichomonas vaginalis PIKK family atypical protein kinase 0.3481 0.745 0.745
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0332 0.067 1
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0055 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0106 0.0183 0.0183
Loa Loa (eye worm) proteasome subunit beta type 2 0.0135 0.0246 0.0246
Onchocerca volvulus Protein ultraspiracle homolog 0.0032 0.0024 0.0196
Echinococcus multilocularis protein patched 0.0088 0.0145 0.0145
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0374 0.076 0.076
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0099 0.0167 0.0167
Brugia malayi nuclear hormone receptor 0.0032 0.0024 0.0024
Entamoeba histolytica hypothetical protein 0.0312 0.0626 0.0626
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0032 0.0024 0.0024
Mycobacterium ulcerans glutaminase 0.028 0.0558 0.9982
Schistosoma mansoni hypothetical protein 0.0312 0.0626 0.0626
Trypanosoma brucei hypothetical protein, conserved 0.0218 0.0425 0.0425
Schistosoma mansoni jumonji/arid domain-containing protein 0.0121 0.0214 0.0214
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0058 0.0058
Leishmania major proteasome beta 5 subunit, putative 0.0281 0.0559 0.0559
Giardia lamblia 20S proteasome alpha subunit 6 0.0055 0.0074 0.0074
Schistosoma mansoni jumonji domain containing protein 0.0032 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0122 0.0217 0.0217
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0055 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0032 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0072 0.011 0.011
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0031 0.0031
Entamoeba histolytica hypothetical protein 0.0902 0.1896 0.1896
Schistosoma mansoni chromobox protein 0.0217 0.0423 0.0423
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.005 0.0062 0.0984
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0091 0.0091
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0031 0.0031
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0036 0.0031 0.0031
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0013 0.0195
Toxoplasma gondii proteasome beta subunit 0.0055 0.0074 0.0086
Loa Loa (eye worm) hypothetical protein 0.0036 0.0031 0.0031
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0055 0.0074 0.0074
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.011 0.0193 0.0193
Loa Loa (eye worm) steroid hormone receptor 0.0032 0.0024 0.0024
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0036 0.0036
Echinococcus granulosus hyperpolarization activated cyclic 0.0027 0.0012 0.0012
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0035 0.0029 0.0029
Loa Loa (eye worm) phosphatidylinositol 3 0.0312 0.0626 0.0626
Trichomonas vaginalis PIKK family atypical protein kinase 0.3481 0.745 0.745
Loa Loa (eye worm) phosphatidylinositol kinase 0.0312 0.0626 0.0626
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0942 0.1983 0.1983
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0032 0.0024 0.0024
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0055 0.0074 0.0074
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0177 0.0336 0.0336
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0032 0.0024 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.372 0.7964 0.7964
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0055 0.0074 0.0074
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.0024 0.0024
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0116 0.0206 0.0206
Loa Loa (eye worm) proteasome subunit beta type 3 0.0055 0.0074 0.0074
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0188 0.036 0.036
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0055 0.0074 0.0074
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0032 0.0024 0.0024
Leishmania major proteasome alpha 1 subunit, putative 0.0055 0.0074 0.0074
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0044 0.0049 0.0049
Schistosoma mansoni inositol monophosphatase 0.0038 0.0036 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0031 0.0031
Schistosoma mansoni hypothetical protein 0.0523 0.108 0.108
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0036 0.0031 0.0029
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0068 0.0101 0.0101
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0032 0.0024 0.0024
Brugia malayi photoreceptor-specific nuclear receptor 0.0032 0.0024 0.0024
Echinococcus multilocularis musashi 0.0028 0.0014 0.0014
Schistosoma mansoni phosphatidylserine receptor 0.0032 0.0024 0.0024
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0068 0.0101 0.0101
Plasmodium falciparum proteasome subunit beta type-4 0.0055 0.0074 0.097
Trichomonas vaginalis immunophilin, putative 0.0116 0.0206 0.0206
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.01 0.0171 0.0171
Trichomonas vaginalis PIKK family atypical protein kinase 0.313 0.6694 0.6694
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0034 0.0034
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0281 0.0559 0.8925
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1647 0.35 0.35
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0027 0.0012 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.0024 0.0024
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0135 0.0246 0.0246
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0034 0.0373
Leishmania major proteasome alpha 7 subunit, putative 0.0055 0.0074 0.0074
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.4666 1 1
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0045 0.0052 0.0052
Schistosoma mansoni hypothetical protein 0.0147 0.0271 0.0271
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.0116 0.0206 1
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.0028 0.0295
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0281 0.0559 0.8941
Echinococcus multilocularis expressed protein 0.0035 0.0029 0.0029
Plasmodium falciparum thioredoxin reductase 0.0048 0.0058 0.0727
Trichomonas vaginalis PIKK family atypical protein kinase 0.2536 0.5414 0.5414
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0404 0.0826 0.0826
Mycobacterium tuberculosis Conserved protein 0.0037 0.0034 0.0547
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0332 0.067 0.0888
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0056 0.0075 0.0075
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0065 0.0065
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0052 0.0066 0.1058
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0902 0.1896 0.1896
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0312 0.0626 0.9327
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0902 0.1896 0.1896
Mycobacterium tuberculosis Conserved hypothetical protein 0.0312 0.0626 1
Echinococcus granulosus ecdysone induced protein 78C 0.0032 0.0024 0.0024
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.0055 0.0074 0.0074
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.0024 0.0024
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0396 0.0808 0.0808
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0063 0.0091 0.0091
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0312 0.0626 0.0626
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0034 0.0612
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0312 0.0626 0.9327
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0055 0.0074 0.097
Trypanosoma cruzi target of rapamycin kinase 3 0.3724 0.7972 0.7972
Echinococcus multilocularis Chromobox protein 3 0.0036 0.0031 0.0031
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0374 0.076 0.076
Giardia lamblia Proteasome subunit beta type 3 0.0055 0.0074 0.0074
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0055 0.0074 0.0074
Brugia malayi proteasome subunit alpha type 2 0.0055 0.0074 0.0074
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0109 0.0189 0.3022
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0469 0.0964 0.0964
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.1647 0.35 0.35
Onchocerca volvulus 0.0032 0.0024 0.0196
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0055 0.0074 0.0074
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0312 0.0626 0.0626
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0055 0.0074 0.0086
Trichomonas vaginalis PIKK family atypical protein kinase 0.372 0.7964 0.7964
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0088 0.0145 0.0145
Echinococcus multilocularis microtubule associated protein 2 0.215 0.4583 0.4583
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0374 0.076 0.076
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0031 0.0031
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0027 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0032 0.0024 0.0024
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0332 0.067 0.067
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0032 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0088 0.0145 0.0145
Brugia malayi M-phase phosphoprotein, mpp8 0.0036 0.0031 0.0031
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0032 0.0024 0.0196
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0332 0.067 0.067
Trichomonas vaginalis PIKK family atypical protein kinase 0.4666 1 1
Schistosoma mansoni peptidase Clp (S14 family) 0.0079 0.0125 0.0125
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0199 0.0384 0.0384
Echinococcus granulosus expressed conserved protein 0.0193 0.0371 0.0371
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0055 0.0074 0.0074
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0055 0.0074 0.0074
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0116 0.0206 0.0206
Echinococcus granulosus expressed protein 0.0035 0.0029 0.0029
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0032 0.0024 0.0024
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0147 0.0271 0.0271
Loa Loa (eye worm) hypothetical protein 0.0037 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0036 0.0031 0.0031
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0312 0.0626 0.0626
Echinococcus multilocularis protein dispatched 1 0.0101 0.0172 0.0172
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0039 0.0039
Echinococcus granulosus jumonji domain containing 1A 0.0032 0.0024 0.0024
Toxoplasma gondii aldehyde dehydrogenase 0.0189 0.0361 0.0472
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0024 0.0024
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.4666 1 1
Echinococcus multilocularis chromobox protein 1 0.0217 0.0423 0.0423
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0511 0.1054 0.1054
Loa Loa (eye worm) acetyltransferase 0.0149 0.0275 0.0275
Schistosoma mansoni voltage-gated potassium channel 0.0038 0.0036 0.0036
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0312 0.0626 0.9327
Entamoeba histolytica hypothetical protein 0.0147 0.0271 0.0271
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0121 0.0216 0.0216
Trypanosoma brucei proteasome beta 7 subunit 0.0055 0.0074 0.0074
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0041 0.0041
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0116 0.0206 0.0206
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0055 0.0074 0.0086
Trypanosoma brucei target of rapamycin kinase 3, putative 0.3724 0.7972 0.7972
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0312 0.0626 0.0626
Schistosoma mansoni cellular tumor antigen P53 0.0102 0.0174 0.0174
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0691 0.1443 0.1443
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0116 0.0206 0.0206
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0031 0.0031
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.005 0.0062 0.11
Loa Loa (eye worm) hypothetical protein 0.0036 0.0031 0.0031
Loa Loa (eye worm) transcription factor SMAD2 0.0126 0.0226 0.0226
Plasmodium vivax glutathione reductase, putative 0.0048 0.0058 0.0727
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0055 0.0074 0.0074
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0091 0.0091
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0039 0.0039
Echinococcus granulosus chromobox protein 1 0.0217 0.0423 0.0423
Loa Loa (eye worm) beta-lactamase 0.0037 0.0034 0.0034
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0055 0.0074 0.0074
Trichomonas vaginalis PIKK family atypical protein kinase 0.0913 0.192 0.192
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0116 0.0206 0.3677
Leishmania major phosphatidylinositol 3-kinase, putative 0.1594 0.3386 0.3386
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0009 0.0009
Toxoplasma gondii peptidylprolyl isomerase 0.0034 0.0028 0.0024
Loa Loa (eye worm) inositol-1 0.0038 0.0036 0.0036
Brugia malayi FAT domain containing protein 0.0692 0.1445 0.1445
Schistosoma mansoni chromobox protein 0.0217 0.0423 0.0423
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0032 0.0024 0.0024
Schistosoma mansoni inositol monophosphatase 0.0038 0.0036 0.0036
Toxoplasma gondii hypothetical protein 0.0027 0.0013 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.1605 0.3411 0.3411
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0058 0.0058
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0014 0.0014
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.003 0.0483
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0353 0.0716 0.0716
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.0055 0.0074 0.5568
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0218 0.0425 0.0425
Echinococcus granulosus chromobox protein 1 0.0217 0.0423 0.0423
Echinococcus granulosus lamin 0.0028 0.0014 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0122 0.0217 0.0217
Mycobacterium ulcerans hypothetical protein 0.0025 0.0009 0.016
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0188 0.036 0.036
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.0055 0.0074 0.0074
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0121 0.0215 0.344
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0332 0.067 0.067
Mycobacterium ulcerans aldehyde dehydrogenase 0.0189 0.0361 0.6454
Brugia malayi Steroid receptor seven-up type 2 0.0032 0.0024 0.0024
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0032 0.0024 0.0024
Onchocerca volvulus 0.0102 0.0175 0.1669
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0038 0.0036 0.232
Brugia malayi hypothetical protein 0.0036 0.0031 0.0031
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0188 0.036 0.036
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0032 0.0024 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.2789 0.596 0.596
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0121 0.0215 0.3338
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0101 0.0101
Echinococcus multilocularis Chromo domain 0.0036 0.0031 0.0031
Giardia lamblia Hypothetical protein 0.0312 0.0626 0.0626
Brugia malayi Niemann-Pick C1 protein precursor 0.0206 0.0398 0.0398
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0902 0.1896 0.1896
Echinococcus multilocularis sterol regulatory element binding protein 0.0088 0.0145 0.0145
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0109 0.0189 0.3022
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0039 0.0039
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0122 0.0217 0.2078
Trichomonas vaginalis chromobox protein, putative 0.0036 0.0031 0.0031
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0055 0.0074 0.0074
Mycobacterium ulcerans hypothetical protein 0.005 0.0062 0.11
Echinococcus granulosus muscleblind protein 0.0145 0.0266 0.0266
Toxoplasma gondii proteasome subunit alpha1, putative 0.0055 0.0074 0.0086
Loa Loa (eye worm) jmjC domain-containing protein 0.0121 0.0214 0.0214
Toxoplasma gondii proteasome subunit 0.0055 0.0074 0.0086
Entamoeba histolytica hypothetical protein 0.0036 0.0031 0.0031
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.1647 0.35 0.35
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0025 0.001 0.0171
Loa Loa (eye worm) hypothetical protein 0.0063 0.0091 0.0091
Brugia malayi Cytochrome P450 family protein 0.0053 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0032 0.0024 0.0024
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0055 0.0074 0.0074
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0121 0.0216 0.0216
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0055 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0037 0.0035 0.0035
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.0055 0.0074 0.0074
Schistosoma mansoni alpha-glucosidase 0.0152 0.0283 0.0283
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0312 0.0626 0.0828
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0511 0.1054 0.1054
Echinococcus multilocularis FTZ F1 alpha 0.0032 0.0024 0.0024
Onchocerca volvulus 0.009 0.0149 0.1417
Loa Loa (eye worm) hypothetical protein 0.0027 0.0013 0.0013
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0055 0.0074 0.0074
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0002 0.0002
Brugia malayi Protein cec-1. 0.0036 0.0031 0.0031
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0692 0.1445 0.1445
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0036 0.0036
Mycobacterium ulcerans hypothetical protein 0.0025 0.0009 0.016
Trichomonas vaginalis PIKK family atypical protein kinase 0.254 0.5422 0.5422
Giardia lamblia Phosphatidylinositol 4-kinase 0.0312 0.0626 0.0626
Loa Loa (eye worm) hypothetical protein 0.0032 0.0024 0.0024
Mycobacterium ulcerans beta-lactamase 0.0037 0.0034 0.0612
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.059 0.1225 0.1225
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0055 0.0074 0.097
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0034 0.0034
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0199 0.0384 0.0384
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0039 0.0039
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0055 0.0074 0.0074
Echinococcus multilocularis citrate lyase subunit beta protein 0.0025 0.0009 0.0009
Brugia malayi MH2 domain containing protein 0.0126 0.0226 0.0226
Loa Loa (eye worm) hypothetical protein 0.0051 0.0065 0.0065
Trypanosoma cruzi hypothetical protein, conserved 0.0218 0.0425 0.0425
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.003 0.0483
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0038 0.0036 0.0648
Loa Loa (eye worm) glutaminase 0.028 0.0558 0.0558
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0913 0.192 0.192
Giardia lamblia Proteasome subunit beta type 9 precursor 0.0055 0.0074 0.0074
Echinococcus multilocularis jumonji domain containing 1A 0.0032 0.0024 0.0024
Onchocerca volvulus 0.0036 0.0031 0.0271
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0032 0.0024 0.0024
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0055 0.0074 0.0074
Schistosoma mansoni lamin 0.0028 0.0014 0.0014
Brugia malayi Proteasome A-type and B-type family protein 0.0281 0.0559 0.0559
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.0028 0.0028
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0055 0.0074 0.097
Brugia malayi AMP-binding enzyme family protein 0.005 0.0062 0.0062
Onchocerca volvulus 0.0099 0.0167 0.1591
Loa Loa (eye worm) hypothetical protein 0.0037 0.0035 0.0035
Brugia malayi chromobox protein homolog 3 0.0122 0.0217 0.0217
Loa Loa (eye worm) hypothetical protein 0.0902 0.1896 0.1896
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0058 0.0058
Echinococcus granulosus proteasome subunit beta t family 0.0055 0.0074 0.0074
Trichomonas vaginalis PIKK family atypical protein kinase 0.3481 0.745 0.745
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0079 0.0125 0.0125
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0032 0.0024 0.0024
Echinococcus multilocularis lysosomal alpha glucosidase 0.0177 0.0336 0.0336
Schistosoma mansoni transient receptor potential channel 0.0074 0.0115 0.0115
Plasmodium vivax proteasome subunit beta type-5, putative 0.0281 0.0559 0.8324
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0055 0.0074 0.097
Trichomonas vaginalis PIKK family atypical protein kinase 0.059 0.1225 0.1225
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0025 0.0009 0.0009
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0116 0.0206 0.0206
Echinococcus multilocularis hyperpolarization activated cyclic 0.0027 0.0012 0.0012
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0691 0.1443 0.1443
Giardia lamblia GTOR 0.4666 1 1
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0055 0.0074 0.0074
Trypanosoma cruzi 20S proteasome subunit 0.0135 0.0246 0.0246
Echinococcus granulosus JmjC domain containing protein 4 0.0032 0.0024 0.0024
Echinococcus multilocularis proteasome subunit alpha type 6 0.0055 0.0074 0.0074
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0055 0.0074 0.097
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0034 0.0034
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0038 0.0036 0.0036
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0055 0.0074 0.0074
Onchocerca volvulus 0.0312 0.0626 0.605
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0034 0.0034
Schistosoma mansoni alpha-glucosidase 0.0152 0.0283 0.0283
Brugia malayi hypothetical protein 0.0033 0.0026 0.0026
Schistosoma mansoni patched 1 0.0088 0.0145 0.0145
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0312 0.0626 0.9327
Echinococcus multilocularis neutral alpha glucosidase AB 0.0039 0.0039 0.0039
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0109 0.0189 0.2914
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0055 0.0074 0.0074
Toxoplasma gondii thioredoxin reductase 0.0048 0.0058 0.0064
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0027 0.0012 0.0012
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0131 0.0237 0.2271
Entamoeba histolytica protein kinase rad3, putative 0.0902 0.1896 0.1896
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.011 0.0193 0.0193
Schistosoma mansoni voltage-gated potassium channel 0.0132 0.024 0.024
Schistosoma mansoni immunophilin 0.0116 0.0206 0.0206
Loa Loa (eye worm) hypothetical protein 0.0692 0.1445 0.1445
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0055 0.0074 0.0074
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0025 0.001 0.0171
Trichomonas vaginalis PIKK family atypical protein kinase 0.3481 0.745 0.745
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0902 0.1896 0.1896
Brugia malayi jmjC domain containing protein 0.0032 0.0024 0.0024
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.1647 0.35 0.35
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0031 0.0031
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0055 0.0074 0.0074
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0055 0.0074 0.097
Trichomonas vaginalis PIKK family atypical protein kinase 0.254 0.5422 0.5422
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.0384 0.0384
Leishmania major 4-coumarate:coa ligase-like protein 0.005 0.0062 0.0062
Trichomonas vaginalis PIKK family atypical protein kinase 0.2536 0.5414 0.5414
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0032 0.0024 0.0024
Toxoplasma gondii heat shock protein hslv, putative 0.0055 0.0074 0.0086
Brugia malayi 20S proteasome alpha5 subunit 0.0055 0.0074 0.0074
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0058 0.0727
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0004 0.0004
Echinococcus multilocularis hyperpolarization activated cyclic 0.0027 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0037 0.0035 0.0035
Schistosoma mansoni alpha glucosidase 0.0039 0.0039 0.0039
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0065 0.0842
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0055 0.0074 0.0074
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0032 0.0024 0.0024
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0055 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.005 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0096 0.0161 0.0161
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0332 0.067 0.0888
Leishmania major proteasome alpha 7 subunit, putative 0.0055 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0037 0.0034 0.0034
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0038 0.0036 0.0036
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0055 0.0074 0.0074
Echinococcus granulosus transient receptor potential ion channel A 0.0097 0.0164 0.0164
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0036 0.0031 0.0031
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0013 0.0058
Toxoplasma gondii peptidase, T1 family protein 0.0055 0.0074 0.0086
Loa Loa (eye worm) hypothetical protein 0.0037 0.0035 0.0035
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0188 0.036 0.036
Echinococcus multilocularis transient receptor potential ion channel A 0.0097 0.0164 0.0164
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0055 0.0074 0.0074
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0109 0.0189 0.3022
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0055 0.0074 0.0074
Echinococcus granulosus histone lysine methyltransferase setb 0.0063 0.0091 0.0091
Trichomonas vaginalis PIKK family atypical protein kinase 0.0312 0.0626 0.0626
Schistosoma mansoni serine/threonine protein kinase 0.0199 0.0384 0.0384
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0055 0.0074 0.0074
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0055 0.0074 0.0074
Mycobacterium tuberculosis Conserved protein 0.0037 0.0034 0.0547
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.4666 1 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0032 0.0024 0.0024
Echinococcus multilocularis fk506 binding protein 0.0116 0.0206 0.0206
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0511 0.1054 0.1054
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0116 0.0206 0.2969
Trichomonas vaginalis chromobox protein, putative 0.0036 0.0031 0.0031
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0055 0.0074 0.0074
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0121 0.0214 0.0214
Trypanosoma brucei glucosidase, putative 0.0039 0.0039 0.0039
Mycobacterium ulcerans lipase LipD 0.0037 0.0034 0.0612
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0055 0.0074 0.0074
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0055 0.0074 0.0074
Schistosoma mansoni thyroid hormone receptor 0.0032 0.0024 0.0024
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0065 0.0842
Echinococcus multilocularis muscleblind protein 1 0.0145 0.0266 0.0266
Loa Loa (eye worm) hypothetical protein 0.0037 0.0034 0.0034
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0055 0.0074 0.0086
Echinococcus granulosus tyrosine protein kinase shark 0.0226 0.0442 0.0442
Plasmodium falciparum glutathione reductase 0.0048 0.0058 0.0727
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0079 0.0125 0.1869
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0374 0.076 0.076
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0116 0.0206 0.0206
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0031 0.0031
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0031 0.0031
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0332 0.067 0.067
Entamoeba histolytica hypothetical protein 0.0025 0.001 0.001
Brugia malayi jmjC domain containing protein 0.0032 0.0024 0.0024
Echinococcus multilocularis chromobox protein 2 0.0036 0.0031 0.0031
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0101 0.0101
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0032 0.0024 0.0024
Brugia malayi steroid hormone receptor 0.0032 0.0024 0.0024
Leishmania major phosphatidylinositol kinase, putative 0.0312 0.0626 0.0626
Loa Loa (eye worm) hypothetical protein 0.0063 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0036 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0312 0.0626 0.0626
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0031 0.0031
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0039 0.0039
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0188 0.036 0.036
Echinococcus granulosus proteasome prosome macropain 0.0281 0.0559 0.0559
Mycobacterium tuberculosis Conserved protein 0.0025 0.0009 0.0143
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0135 0.0246 0.0318
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0055 0.0074 0.0074
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0055 0.0074 0.0086
Schistosoma mansoni hypothetical protein 0.0523 0.108 0.108
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0116 0.0206 0.2969
Loa Loa (eye worm) hypothetical protein 0.0145 0.0266 0.0266
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0068 0.0101 0.0101
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0041 0.0041
Leishmania major proteasome alpha 3 subunit, putative 0.0055 0.0074 0.0074
Trichomonas vaginalis PIKK family atypical protein kinase 0.2789 0.596 0.596
Echinococcus granulosus proteasome subunit beta type 6 0.0055 0.0074 0.0074
Trichomonas vaginalis Heterochromatin protein, putative 0.0036 0.0031 0.0031
Leishmania major hypothetical protein, conserved 0.0051 0.0065 0.0065
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0332 0.067 0.067
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0036 0.0036
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0068 0.0101 0.0101
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0034 0.0547
Schistosoma mansoni tyrosine kinase 0.0221 0.0431 0.0431
Echinococcus granulosus neutral alpha glucosidase AB 0.0039 0.0039 0.0039
Leishmania major proteasome alpha 1 subunit, putative 0.0055 0.0074 0.0074
Schistosoma mansoni rotamase 0.0035 0.0029 0.0029
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0055 0.0074 0.097
Leishmania major trypanothione reductase 0.0048 0.0058 0.0058
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0188 0.036 0.036
Trichomonas vaginalis PIKK family atypical protein kinase 0.2536 0.5414 0.5414
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0036 0.0031 0.0029
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0055 0.0074 0.0074
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0439 0.0901 0.0901
Schistosoma mansoni microtubule-associated protein tau 0.215 0.4583 0.4583
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0031 0.0031
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0039 0.0039 0.004
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0032 0.0024 0.0024
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.003 0.0483
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0036 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0036 0.0031 0.0031
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0035 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.01 0.0171 0.0171
Brugia malayi acetyltransferase, GNAT family protein 0.0149 0.0275 0.0275
Echinococcus granulosus tumor protein p63 0.0696 0.1452 0.1452
Brugia malayi proteasome subunit beta type 3 0.0055 0.0074 0.0074
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0079 0.0125 0.2229
Echinococcus granulosus sterol regulatory element binding protein 0.0088 0.0145 0.0145
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0036 0.0031 0.0332
Schistosoma mansoni jumonji domain containing protein 0.0121 0.0214 0.0214
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0189 0.0361 0.5771
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0034 0.0034
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0034 0.0034
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0079 0.0125 0.0155
Schistosoma mansoni voltage-gated potassium channel 0.0132 0.024 0.024
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0199 0.0384 0.0384
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0055 0.0074 0.0074
Loa Loa (eye worm) phosphatidylinositol 3 0.0312 0.0626 0.0626
Echinococcus granulosus histone acetyltransferase KAT2B 0.0144 0.0266 0.0266
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0149 0.0275 0.0275
Echinococcus multilocularis JmjC domain containing protein 4 0.0032 0.0024 0.0024
Trichomonas vaginalis maltase-glucoamylase, putative 0.0039 0.0039 0.0039
Schistosoma mansoni hypothetical protein 0.0085 0.0138 0.0138
Trichomonas vaginalis PIKK family atypical protein kinase 0.4666 1 1
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.005 0.0062 0.0844
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.0024 0.0024
Schistosoma mansoni transient receptor potential channel 4 0.0108 0.0188 0.0188
Echinococcus multilocularis tyrosine protein kinase shark 0.0226 0.0442 0.0442
Toxoplasma gondii ABC1 family protein 0.0037 0.0034 0.0033
Brugia malayi Proteasome A-type and B-type family protein 0.0055 0.0074 0.0074
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0036 0.0031 0.0332
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0055 0.0074 0.097
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.0055 0.0074 0.0074
Trichomonas vaginalis rotamase, putative 0.0034 0.0028 0.0028
Brugia malayi hypothetical protein 0.0051 0.0065 0.0065
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0312 0.0626 0.0626
Loa Loa (eye worm) hypothetical protein 0.0206 0.0398 0.0398
Mycobacterium tuberculosis Probable oxidoreductase 0.0121 0.0215 0.344
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0032 0.0024 0.0024
Mycobacterium ulcerans hypothetical protein 0.0037 0.0034 0.0612
Echinococcus granulosus phd:f box containing protein 0.0032 0.0024 0.0024
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0116 0.0206 0.0206
Echinococcus multilocularis peptidase Clp (S14 family) 0.0052 0.0066 0.0066
Brugia malayi CHE-14 protein 0.0088 0.0145 0.0145
Brugia malayi Proteasome A-type and B-type family protein 0.0055 0.0074 0.0074
Loa Loa (eye worm) phosphatidylinositol 3 0.0312 0.0626 0.0626
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0189 0.0361 0.0361
Schistosoma mansoni jumonji/arid domain-containing protein 0.0121 0.0214 0.0214
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.0384 0.0384
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0032 0.0024 0.0024
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0091 0.0091
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0332 0.067 0.067
Loa Loa (eye worm) hypothetical protein 0.0108 0.0188 0.0188
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0027 0.0012 0.0012
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0218 0.0425 0.6283
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0029 0.0029
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.2199 0.4689 0.4689
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0055 0.0074 0.0074
Loa Loa (eye worm) phosphatidylinositol 3 0.1605 0.3411 0.3411
Brugia malayi beta-lactamase family protein 0.0037 0.0034 0.0034
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.009 0.0149 0.0149
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.0055 0.0074 0.0074
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0116 0.0206 0.0206
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0188 0.036 0.036
Brugia malayi Heterochromatin protein 1 0.0217 0.0423 0.0423
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0024 0.0024
Schistosoma mansoni kinase 0.0101 0.0173 0.0173
Loa Loa (eye worm) hypothetical protein 0.005 0.0062 0.0062
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.058 0.1203 0.1203
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0055 0.0074 0.0074
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0085 0.0137 0.0137
Echinococcus granulosus neuropeptide s receptor 0.1446 0.3069 0.3069
Trichomonas vaginalis conserved hypothetical protein 0.0692 0.1445 0.1445
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0209 0.0405 0.0405
Trichomonas vaginalis chromobox protein, putative 0.0217 0.0423 0.0423
Loa Loa (eye worm) hypothetical protein 0.0027 0.0012 0.0012
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0374 0.076 0.076
Trichomonas vaginalis PIKK family atypical protein kinase 0.3973 0.8509 0.8509
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.009 0.0149 0.0149
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0438 0.0899 0.0899
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0121 0.0216 0.0216
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0055 0.0074 0.0074
Schistosoma mansoni aldehyde dehydrogenase 0.0189 0.0361 0.0361
Schistosoma mansoni RAR-like nuclear receptor 0.0032 0.0024 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.059 0.1225 0.1225
Echinococcus multilocularis proteasome subunit beta type 7 0.0055 0.0074 0.0074
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0079 0.0125 0.0155
Trichomonas vaginalis hypothetical protein 0.0036 0.0031 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.2778 0.5936 0.5936
Echinococcus multilocularis neuropeptide receptor A26 0.1446 0.3069 0.3069
Trichomonas vaginalis PIKK family atypical protein kinase 0.372 0.7964 0.7964
Entamoeba histolytica hypothetical protein 0.0312 0.0626 0.0626
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0038 0.0036 0.0036
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0031 0.0031
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.0024 0.0024
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0034 0.0034
Echinococcus granulosus transient receptor potential gamma protein 0.0108 0.0188 0.0188
Leishmania major hypothetical protein, unknown function 0.0312 0.0626 0.0626
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0281 0.0559 0.0559
Loa Loa (eye worm) phosphatidylinositol 3 0.4666 1 1
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0037 0.0035 0.0553
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0036 0.0036
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0014 0.0014
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0055 0.0074 0.0074
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0014 0.0014
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0281 0.0559 0.0559
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0063 0.0091 0.0091
Onchocerca volvulus 0.0312 0.0626 0.605
Schistosoma mansoni nuclear hormone receptor 0.0032 0.0024 0.0024
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0446 0.0916 0.0916
Echinococcus multilocularis serine protein kinase ATM 0.0902 0.1896 0.1896
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0065 0.0842
Trichomonas vaginalis PIKK family atypical protein kinase 0.2789 0.596 0.596
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0135 0.0246 0.0246
Trichomonas vaginalis PIKK family atypical protein kinase 0.1594 0.3386 0.3386
Plasmodium vivax proteasome subunit beta type-6, putative 0.0055 0.0074 0.097
Trichomonas vaginalis conserved hypothetical protein 0.0088 0.0145 0.0145
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0034 0.0547
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0034 0.0547
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0332 0.067 0.067
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0039 0.0039
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0167 0.0167
Schistosoma mansoni glutaminase 0.028 0.0558 0.0558
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0037 0.0034 0.0034
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0052 0.0066 0.0066
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0281 0.0559 0.0559
Echinococcus granulosus lamin dm0 0.0028 0.0014 0.0014
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0036 0.0036
Trypanosoma brucei trypanothione reductase 0.0048 0.0058 0.0058
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0135 0.0246 0.0246
Brugia malayi AMP-binding enzyme family protein 0.005 0.0062 0.0062
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0027 0.0012 0.0012
Echinococcus multilocularis chromobox protein 1 0.0217 0.0423 0.0423
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0032 0.0024 0.0024
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0312 0.0626 0.0626
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0055 0.0074 0.0074
Toxoplasma gondii target of rapamycin (TOR), putative 0.3481 0.745 1
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0332 0.067 1
Schistosoma mansoni chromobox protein 0.0036 0.0031 0.0031
Echinococcus multilocularis expressed conserved protein 0.0193 0.0371 0.0371
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0036 0.0036
Onchocerca volvulus 0.0096 0.0161 0.1526
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0079 0.0125 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0062 0.0984
Trichomonas vaginalis PIKK family atypical protein kinase 0.1594 0.3386 0.3386
Leishmania major proteasome alpha 2 subunit, putative 0.0055 0.0074 0.0074
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0055 0.0074 0.0074
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0055 0.0074 0.0074
Loa Loa (eye worm) cytochrome P450 family protein 0.0053 0.0069 0.0069
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.0024 0.0024
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0031 0.0031
Echinococcus multilocularis neuropeptide s receptor 0.1446 0.3069 0.3069
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0079 0.0125 0.0125
Loa Loa (eye worm) phosphatidylinositol 3 0.0649 0.1353 0.1353
Onchocerca volvulus 0.0028 0.0014 0.0104
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0312 0.0626 0.0626
Trichomonas vaginalis PIKK family atypical protein kinase 0.1594 0.3386 0.3386
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.0384 0.0384
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0062 0.11
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0055 0.0074 0.0074
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.4666 1 1
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0025 0.0009 0.0143
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0024 0.0024
Schistosoma mansoni intermediate filament proteins 0.0028 0.0014 0.0014
Entamoeba histolytica hypothetical protein 0.0036 0.0031 0.0031
Loa Loa (eye worm) FKBP5 protein 0.0116 0.0206 0.0206
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0031 0.0332
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3298 0.7055 0.7055
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0312 0.0626 0.0626
Leishmania major phosphopantetheinyl transferase-like protein 0.0025 0.001 0.001
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0044 0.0049 0.0053
Loa Loa (eye worm) hypothetical protein 0.0032 0.0024 0.0024
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0511 0.1054 0.1054
Echinococcus multilocularis proteasome (prosome, macropain) 0.0281 0.0559 0.0559
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0055 0.0074 0.0074
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0511 0.1054 0.1054
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0009 0.0009
Leishmania major hypothetical protein, conserved 0.0407 0.083 0.083
Schistosoma mansoni 60S ribosomal protein L21 0.0022 0.0002 0.0002
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.0055 0.0074 0.104
Mycobacterium ulcerans aldehyde dehydrogenase 0.0189 0.0361 0.6454
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0902 0.1896 0.1896
Onchocerca volvulus Serine\/threonine kinase homolog 0.0199 0.0384 0.3703
Brugia malayi AMP-binding enzyme family protein 0.005 0.0062 0.0062
Onchocerca volvulus 0.005 0.0062 0.0563
Loa Loa (eye worm) hypothetical protein 0.0037 0.0034 0.0034
Leishmania major proteasome beta 7 subunit, putative 0.0055 0.0074 0.0074
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0312 0.0626 0.0626
Onchocerca volvulus 0.0037 0.0034 0.0298
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.009 0.0149 0.0149
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.0384 0.0384
Leishmania major phosphatidylinositol 4-kinase, putative 0.0312 0.0626 0.0626
Brugia malayi jmjC domain containing protein 0.0121 0.0214 0.0214
Trichomonas vaginalis PIKK family atypical protein kinase 0.0902 0.1896 0.1896
Leishmania major proteasome beta 2 subunit, putative 0.0135 0.0246 0.0246
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0034 0.0034
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0116 0.0206 0.0206
Giardia lamblia 20S proteasome alpha subunit 1 0.0055 0.0074 0.0074
Loa Loa (eye worm) MH2 domain-containing protein 0.0126 0.0226 0.0226
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0235 0.0462 0.7381
Brugia malayi proteasome subunit alpha type 6 0.0055 0.0074 0.0074
Brugia malayi proteasome subunit alpha type 1 0.0055 0.0074 0.0074
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.0384 0.0384
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0032 0.0024 0.0024
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0055 0.0074 0.0074
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0332 0.067 0.067
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0055 0.0074 0.0074
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0055 0.0074 0.0074
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0027 0.0012 0.0012
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0167 0.0167
Brugia malayi Pre-SET motif family protein 0.0063 0.0091 0.0091
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0055 0.0074 0.0074
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0032 0.0024 0.0024
Brugia malayi Probable ClpP-like protease 0.0079 0.0125 0.0125
Loa Loa (eye worm) glutathione reductase 0.0048 0.0058 0.0058
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0004 0.0004
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0052 0.0066 0.1058
Echinococcus granulosus lysine specific demethylase 6a 0.0032 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0085 0.0137 0.0137
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0218 0.0425 0.0425
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0032 0.0024 0.0024
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.1605 0.3411 0.3411
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0332 0.067 0.067
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0045 0.0052 0.0052
Leishmania major proteasome beta 2 subunit, putative 0.0055 0.0074 0.0074
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0218 0.0425 0.0425
Schistosoma mansoni thyroid hormone receptor 0.0032 0.0024 0.0024
Echinococcus granulosus peptidase Clp S14 family 0.0052 0.0066 0.0066
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.01 0.0171 0.0171
Plasmodium vivax proteasome subunit beta type-7, putative 0.0055 0.0074 0.097
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0058 0.092
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0116 0.0206 0.0206
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0028 0.0443
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0055 0.0074 0.0074
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.0024 0.0024
Mycobacterium ulcerans proteasome PrcA 0.0055 0.0074 0.1317
Schistosoma mansoni hypothetical protein 0.0035 0.0031 0.0031
Giardia lamblia Proteasome subunit beta type 1 0.0218 0.0425 0.0425
Trichomonas vaginalis chromobox protein, putative 0.0036 0.0031 0.0031
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.0055 0.0074 0.0074
Leishmania major hypothetical protein, conserved 0.0037 0.0034 0.0034
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0027 0.0012 0.0012
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0055 0.0074 0.0074
Mycobacterium tuberculosis Conserved protein 0.0037 0.0034 0.0547
Onchocerca volvulus 0.05 0.1032 1
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0332 0.067 0.067
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0149 0.0275 0.0275
Trichomonas vaginalis conserved hypothetical protein 0.1004 0.2116 0.2116
Loa Loa (eye worm) helicase 0.0036 0.0031 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.254 0.5422 0.5422
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0031 0.0031
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0034 0.0547
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0218 0.0425 0.0558
Schistosoma mansoni fkbp-rapamycin associated protein 0.0902 0.1896 0.1896
Leishmania major alpha glucosidase II subunit, putative 0.0039 0.0039 0.0039
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0037 0.0035 0.2174
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0055 0.0074 0.0074
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0218 0.0425 0.0425
Brugia malayi jmjC domain containing protein 0.0032 0.0024 0.0024
Loa Loa (eye worm) proteasome subunit beta type 1 0.0218 0.0425 0.0425
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0055 0.0074 0.0086
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0079 0.0125 1
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0039 0.0039
Entamoeba histolytica hypothetical protein 0.0147 0.0271 0.0271
Loa Loa (eye worm) hypothetical protein 0.0032 0.0024 0.0024
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0032 0.0024 0.0024
Brugia malayi proteasome subunit beta type 1 0.0218 0.0425 0.0425
Leishmania major peptidylprolyl isomerase-like protein 0.0116 0.0206 0.0206
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0031 0.0031
Brugia malayi jmjC domain containing protein 0.0121 0.0214 0.0214
Echinococcus granulosus proteasome subunit alpha type 2 0.0055 0.0074 0.0074
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0044 0.0049 0.0597
Trichomonas vaginalis set domain proteins, putative 0.05 0.1032 0.1032
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0032 0.0024 0.0024
Echinococcus granulosus short transient receptor potential channel 6 0.0074 0.0115 0.0115
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0027 0.0012 0.0012
Schistosoma mansoni transcription factor LCR-F1 0.0147 0.0271 0.0271
Schistosoma mansoni hypothetical protein 0.0085 0.0138 0.0138
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0055 0.0074 0.0074
Trypanosoma brucei proteasome alpha 7 subunit 0.0055 0.0074 0.0074
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0055 0.0074 0.0074
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.1594 0.3386 0.3386
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0055 0.0074 0.0074
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.195 0.4152 0.4152
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0511 0.1054 0.1054
Echinococcus granulosus short transient receptor potential channel 6 0.0074 0.0115 0.0115
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0032 0.0024 0.0024
Plasmodium vivax proteasome subunit beta type-2, putative 0.0135 0.0246 0.3578
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0055 0.0074 0.0074
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0902 0.1896 0.1896
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.0055 0.0074 0.097
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0438 0.0899 0.0899
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0025 0.0009 0.016
Loa Loa (eye worm) hypothetical protein 0.0032 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0037 0.0034 0.0034
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.3724 0.7972 0.7972
Echinococcus multilocularis 0.0312 0.0626 0.0626
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0055 0.0074 0.097
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0055 0.0074 0.0074
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0055 0.0074 0.0074
Onchocerca volvulus Bile acid receptor homolog 0.0032 0.0024 0.0196
Trichomonas vaginalis conserved hypothetical protein 0.0086 0.0141 0.0141
Entamoeba histolytica acyl-coA synthetase, putative 0.005 0.0062 0.0062
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0031 0.0031
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0055 0.0074 0.097
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0055 0.0074 0.0074
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0044 0.0049 0.0053
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0027 0.0012 0.0012
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0034 0.0547
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0332 0.067 0.067
Giardia lamblia 20S proteasome alpha subunit 7 0.0055 0.0074 0.0074
Echinococcus multilocularis geminin 0.0523 0.108 0.108
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0034 0.0034
Brugia malayi Calcitonin receptor-like protein seb-1 0.0052 0.0066 0.0066
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0312 0.0626 0.0626
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0034 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0031 0.0031
Echinococcus granulosus lysosomal alpha glucosidase 0.0177 0.0336 0.0336
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0116 0.0206 0.0206
Toxoplasma gondii FATC domain-containing protein 0.0902 0.1896 0.2535
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.0024 0.0024
Mycobacterium leprae conserved hypothetical protein 0.0312 0.0626 1
Brugia malayi SET domain containing protein 0.0038 0.0036 0.0036
Entamoeba histolytica proteasome subunit beta type 3, putative 0.0055 0.0074 0.0074
Echinococcus multilocularis proteasome subunit beta type 6 0.0055 0.0074 0.0074
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0188 0.036 0.036
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0102 0.0174 0.0174
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0374 0.076 0.076
Toxoplasma gondii proteasome subunit alpha type, putative 0.0055 0.0074 0.0086
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0055 0.0074 0.0074
Plasmodium vivax hypothetical protein 0.0312 0.0626 0.9327
Plasmodium vivax hypothetical protein, conserved 0.0312 0.0626 0.9327
Loa Loa (eye worm) hypothetical protein 0.0036 0.0031 0.0031
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0312 0.0626 0.0626
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.0024 0.0024
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0055 0.0074 0.0074
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.0055 0.0074 0.0074
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0085 0.0137 0.0137
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0374 0.076 0.076
Echinococcus multilocularis Zinc finger, PHD finger 0.0332 0.067 0.067
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0055 0.0074 0.0074
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0009 0.0009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0032 0.0024 0.0024
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.4666 1 1
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0055 0.0074 0.0074
Plasmodium vivax heterochromatin protein 1, putative 0.0036 0.0031 0.0332
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0281 0.0559 0.0559
Trypanosoma brucei polo-like protein kinase 0.0199 0.0384 0.0384
Leishmania major hypothetical protein, conserved 0.0032 0.0024 0.0024
Onchocerca volvulus 0.0028 0.0014 0.0104
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0036 0.0031 0.0031
Schistosoma mansoni immunophilin 0.0116 0.0206 0.0206
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0281 0.0559 0.0559
Brugia malayi serine/threonine-protein kinase plk-2 0.0199 0.0384 0.0384
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0199 0.0383 0.0383
Mycobacterium ulcerans fatty-acid-CoA ligase 0.005 0.0062 0.11
Echinococcus granulosus histone acetyltransferase KAT2B 0.0044 0.0049 0.0049
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.0062 0.11
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0055 0.0074 0.0074
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0055 0.0074 0.0074
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0135 0.0246 0.0246
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0206 0.0398 0.0398
Trichomonas vaginalis PIKK family atypical protein kinase 0.1594 0.3386 0.3386
Brugia malayi Proteasome subunit alpha type 7-1 0.0055 0.0074 0.0074
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0041 0.0478
Loa Loa (eye worm) hypothetical protein 0.0034 0.0028 0.0028
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0116 0.0206 0.0206
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0055 0.0074 0.097
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0116 0.0206 0.0206
Brugia malayi Pre-SET motif family protein 0.0439 0.0901 0.0901
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0055 0.0074 0.0074
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0312 0.0626 0.0626
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0031 0.0031
Loa Loa (eye worm) PAS-3 protein 0.0055 0.0074 0.0074
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0332 0.067 0.067
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0032 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0438 0.0899 0.0899
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.4666 1 1
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0055 0.0074 0.097
Leishmania major fk506-binding protein 1-like protein 0.0116 0.0206 0.0206
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0055 0.0074 0.0074
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0039 0.0039
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0116 0.0206 0.0206
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0055 0.0074 0.0074
Brugia malayi Cyclic-nucleotide gated cation channel 0.0027 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0036 0.0031 0.0031
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0055 0.0074 0.0074
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0036 0.0036
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.0384 0.0384
Brugia malayi Transient-receptor-potential like protein 0.0045 0.0052 0.0052
Loa Loa (eye worm) CHromoDomain protein family member 0.0036 0.0031 0.0031
Echinococcus granulosus serine protein kinase ATM 0.0902 0.1896 0.1896
Brugia malayi hypothetical protein 0.0147 0.0271 0.0271
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0101 0.0101
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0032 0.0024 0.0024
Plasmodium vivax proteasome subunit beta type-4, putative 0.0055 0.0074 0.097
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0218 0.0425 0.0425
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0116 0.0206 0.0206
Echinococcus granulosus Chromobox protein 3 0.0036 0.0031 0.0031
Toxoplasma gondii proteasome subunit beta type, putative 0.0281 0.0559 0.0739
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0691 0.1443 0.1443
Echinococcus granulosus chromobox protein 2 0.0036 0.0031 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.3481 0.745 0.745
Trichomonas vaginalis PIKK family atypical protein kinase 0.254 0.5422 0.5422
Giardia lamblia 20S proteasome alpha subunit 5 0.0055 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.005 0.0062 0.0062
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0036 0.0031 0.0031
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0079 0.0125 0.587
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0052 0.0066 0.0066
Schistosoma mansoni protein phosphatase 2C 0.0032 0.0024 0.0024
Leishmania major phosphatidylinositol 3-kinase, putative 0.0332 0.067 0.067
Trichomonas vaginalis PIKK family atypical protein kinase 0.0902 0.1896 0.1896
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0034 0.0028 0.0028
Leishmania major 4-coumarate:coa ligase-like protein 0.005 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0145 0.0266 0.0266
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0055 0.0074 0.0074
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0034 0.0034
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0025 0.0009 0.016
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0055 0.0074 0.0074
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0036 0.0031 0.0029
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0055 0.0074 0.097
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0055 0.0074 0.0074
Brugia malayi ecdysteroid receptor 0.0032 0.0024 0.0024
Schistosoma mansoni phd/f-box containing protein 0.0032 0.0024 0.0024
Echinococcus granulosus microtubule associated protein 2 0.215 0.4583 0.4583
Mycobacterium ulcerans aldehyde dehydrogenase 0.0189 0.0361 0.6454
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0055 0.0074 0.0074
Giardia lamblia 20S proteasome alpha subunit 2 0.0055 0.0074 0.0074
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0036 0.0031 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0086 0.0141 0.0141
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0312 0.0626 0.0626
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0034 0.0028 0.0028
Brugia malayi proteasome subunit alpha type 4 0.0055 0.0074 0.0074
Brugia malayi Proteasome subunit alpha type 1 0.0055 0.0074 0.0074
Echinococcus multilocularis short transient receptor potential channel 6 0.0074 0.0115 0.0115
Brugia malayi Inositol-1 0.0038 0.0036 0.0036
Echinococcus multilocularis lamin dm0 0.0028 0.0014 0.0014

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

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