Detailed information for compound 1964007

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 513.472 | Formula: C24H22F3N7O3
  • H donors: 3 H acceptors: 7 LogP: 1 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 2
  • SMILES: OCC(n1cc(c2c1nc(N)nc2)C(=O)c1cncc(c1)NC(=O)Cc1ccc(cn1)C(F)(F)F)(C)C
  • InChi: 1S/C24H22F3N7O3/c1-23(2,12-35)34-11-18(17-10-31-22(28)33-21(17)34)20(37)13-5-16(9-29-7-13)32-19(36)6-15-4-3-14(8-30-15)24(25,26)27/h3-5,7-11,35H,6,12H2,1-2H3,(H,32,36)(H2,28,31,33)
  • InChiKey: IJERLKDAMJMGBO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens neurotrophic tyrosine kinase, receptor, type 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi putative serine/threonine kinase SADA gamma 0.011 0.0202 0.0202
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0092 0.0083 0.0134
Trichomonas vaginalis AGC family protein kinase 0.0152 0.0473 0.0446
Schistosoma mansoni vam6/vps39 related 0.011 0.0204 0.033
Trichomonas vaginalis CMGC family protein kinase 0.0149 0.0455 0.0428
Echinococcus multilocularis serine:threonine protein kinase N2 0.0128 0.0319 0.0516
Schistosoma mansoni unc-13 (munc13) 0.0092 0.0087 0.014
Schistosoma mansoni serine/threonine protein kinase 0.0295 0.1408 0.2276
Entamoeba histolytica protein kinase, putative 0.0143 0.0413 0.0391
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0615 0.0995
Schistosoma mansoni tyrosine kinase 0.0331 0.1644 0.2658
Entamoeba histolytica protein kinase, putative 0.0162 0.0543 0.0521
Onchocerca volvulus 0.0301 0.1444 0.4636
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0121 0.0276 0.0439
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0152 0.0475 0.0475
Echinococcus multilocularis unc 13 (munc13) 0.0092 0.0087 0.014
Brugia malayi casein kinase 1, delta 0.0129 0.0326 0.0326
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0259 0.1172 0.1895
Leishmania major casein kinase, putative 0.0129 0.0326 0.0769
Trichomonas vaginalis AGC family protein kinase 0.1614 1 1
Entamoeba histolytica protein kinase domain containing protein 0.0149 0.0455 0.0433
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.013 0.0334 0.0334
Trichomonas vaginalis CAMK family protein kinase 0.0289 0.1366 0.1342
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0165 0.0559 0.0903
Loa Loa (eye worm) TK/FER protein kinase 0.0121 0.027 0.027
Entamoeba histolytica protein kinase, putative 0.0238 0.1035 0.1014
Schistosoma mansoni casein kinase II beta subunit 0.0083 0.0028 0.0045
Loa Loa (eye worm) TK/EGFR protein kinase 0.0462 0.2494 0.2494
Trichomonas vaginalis CAMK family protein kinase 0.011 0.0202 0.0175
Entamoeba histolytica protein kinase, putative 0.0092 0.0083 0.006
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0083 0.0028 0.0005
Echinococcus multilocularis nervana 2 0.0897 0.5329 0.8616
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0156 0.0503 0.084
Trichomonas vaginalis AGC family protein kinase 0.0102 0.0151 0.0124
Schistosoma mansoni protein kinase C 0.0092 0.0087 0.014
Echinococcus multilocularis Immunoglobulin 0.0082 0.0022 0.0035
Brugia malayi protein kinase C II. 0.0968 0.5789 0.5789
Entamoeba histolytica protein kinase, putative 0.0102 0.0151 0.0129
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0184 0.0683 0.1103
Echinococcus granulosus cyclin dependent kinase 0.0334 0.1661 0.2685
Loa Loa (eye worm) TK protein kinase 0.0268 0.1233 0.1233
Echinococcus multilocularis epidermal growth factor receptor 0.0462 0.2494 0.4032
Schistosoma mansoni tyrosine kinase 0.0256 0.1152 0.1863
Echinococcus granulosus cyclin dependent kinase 7 0.013 0.0334 0.054
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0159 0.0521 0.0801
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0205 0.0822 0.1329
Brugia malayi Doublecortin family protein 0.0171 0.0597 0.0597
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0215 0.0882 0.2203
Onchocerca volvulus 0.011 0.0198 0.0559
Schistosoma mansoni protein kinase 0.0105 0.0172 0.0278
Entamoeba histolytica protein kinase, putative 0.064 0.3654 0.364
Trypanosoma brucei casein kinase I, isoform 2 0.0129 0.0326 0.0299
Plasmodium falciparum calcium-dependent protein kinase 4 0.0121 0.0276 0.0439
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0275 0.1279 0.1279
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0102 0.0148 0.0213
Schistosoma mansoni tyrosine kinase 0.0325 0.1601 0.2588
Echinococcus multilocularis c src tyrosine kinase 0.0174 0.0617 0.0997
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0418 0.2205 0.3565
Giardia lamblia Kinase, CMGC GSK 0.0149 0.0455 0.0755
Trypanosoma cruzi casein kinase, putative 0.0129 0.0326 0.0485
Echinococcus multilocularis casein kinase I delta 0.0129 0.0326 0.0527
Schistosoma mansoni serine/threonine protein kinase 0.011 0.0202 0.0327
Toxoplasma gondii AGC kinase 0.0679 0.3907 0.4099
Trichomonas vaginalis AGC family protein kinase 0.0152 0.0473 0.0446
Trichomonas vaginalis CAMK family protein kinase 0.011 0.0202 0.0175
Schistosoma mansoni serine/threonine protein kinase 0.0129 0.0326 0.0527
Trypanosoma cruzi polo-like protein kinase, putative 0.0289 0.1366 0.2173
Schistosoma mansoni protein kinase 0.0424 0.2249 0.3637
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0205 0.0822 0.0822
Echinococcus granulosus FERM and pleckstrin domain containing protein 0.0083 0.0026 0.0042
Brugia malayi Hr1 repeat family protein 0.0768 0.4488 0.4488
Loa Loa (eye worm) TK/FER protein kinase 0.042 0.2222 0.2222
Echinococcus granulosus protein kinase shaggy 0.0149 0.0455 0.0735
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0289 0.1366 0.2208
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0121 0.0276 0.0446
Trichomonas vaginalis CAMK family protein kinase 0.0289 0.1366 0.1342
Toxoplasma gondii AGC kinase 0.0679 0.3907 0.4099
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0143 0.0413 0.0413
Trichomonas vaginalis AGC family protein kinase 0.1614 1 1
Trichomonas vaginalis CMGC family protein kinase 0.0163 0.0548 0.0522
Trichomonas vaginalis CMGC family protein kinase 0.0159 0.0521 0.0495
Schistosoma mansoni tyrosine kinase 0.0082 0.002 0.0032
Plasmodium falciparum calcium-dependent protein kinase 7 0.0131 0.0341 0.0554
Echinococcus granulosus serine:threonine protein kinase 0.0135 0.0361 0.0584
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0121 0.0276 0.0446
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.022 0.0918 0.1485
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0179 0.0651 0.0651
Echinococcus granulosus serine/threonine protein kinase 0.1029 0.6185 1
Trichomonas vaginalis AGC family protein kinase 0.064 0.3654 0.3637
Echinococcus granulosus tyrosine protein kinase Fps85D 0.042 0.2222 0.3593
Echinococcus multilocularis cyclin dependent kinase 0.0334 0.1661 0.2685
Onchocerca volvulus 0.0149 0.0455 0.1398
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0952 0.5687 0.5687
Loa Loa (eye worm) hypothetical protein 0.0082 0.0022 0.0022
Echinococcus granulosus hypothetical protein 0.0119 0.0262 0.0423
Onchocerca volvulus 0.0141 0.0404 0.1232
Entamoeba histolytica hypothetical protein 0.0375 0.193 0.1912
Trichomonas vaginalis CAMK family protein kinase 0.0135 0.0367 0.0341
Schistosoma mansoni serine/threonine protein kinase 0.0205 0.0822 0.133
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0104 0.0162 0.0134
Schistosoma mansoni atypical protein kinase C 0.0811 0.4764 0.7704
Onchocerca volvulus 0.0121 0.027 0.0795
Echinococcus granulosus serine:threonine kinase SAD 1 0.011 0.0202 0.0327
Loa Loa (eye worm) TK protein kinase 0.0307 0.1487 0.1487
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0411 0.2163 0.2163
Schistosoma mansoni tyrosine kinase 0.0361 0.1834 0.2965
Echinococcus multilocularis serine:threonine protein kinase 38 0.064 0.3654 0.5908
Echinococcus multilocularis casein kinase ii subunit beta 0.0083 0.0028 0.0044
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0104 0.0162 0.0162
Trichomonas vaginalis CAMK family protein kinase 0.0135 0.0367 0.0341
Brugia malayi Immunoglobulin I-set domain containing protein 0.0098 0.0123 0.0123
Brugia malayi Tyrosine-protein kinase abl-1 0.0252 0.1127 0.1127
Onchocerca volvulus 0.0099 0.0129 0.0333
Schistosoma mansoni serine/threonine protein kinase 0.0166 0.0563 0.091
Brugia malayi STE20-like kinase MST 0.0275 0.1279 0.1279
Brugia malayi Serine/threonine-protein kinase SULU 0.0241 0.1057 0.1057
Echinococcus multilocularis FERM and pleckstrin domain containing protein 0.0083 0.0026 0.0042
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0104 0.0162 0.0346
Brugia malayi Protein kinase domain containing protein 0.0121 0.027 0.027
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0614 0.3487 0.3487
Onchocerca volvulus 0.0121 0.027 0.0795
Schistosoma mansoni protein kinase 0.0384 0.1987 0.3212
Echinococcus granulosus raf serine:threonine protein kinase 0.0134 0.0356 0.0575
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.011 0.0202 0.045
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0235 0.1017 0.1644
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0625 0.3553 0.5744
Schistosoma mansoni serine/threonine protein kinase 0.011 0.0205 0.0331
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0384 0.1987 0.3212
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.011 0.0204 0.033
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0149 0.0455 0.0455
Plasmodium falciparum serine/threonine protein kinase KIN 0.011 0.0202 0.0309
Trichomonas vaginalis CAMK family protein kinase 0.011 0.0202 0.0175
Brugia malayi Protein kinase domain containing protein 0.0236 0.1023 0.1023
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0092 0.0083 0.0134
Brugia malayi Protein kinase domain containing protein 0.0952 0.5687 0.5687
Trichomonas vaginalis AGC family protein kinase 0.0679 0.3907 0.389
Giardia lamblia Kinase, STE STE20 0.0107 0.018 0.027
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.037 0.1895 0.3064
Echinococcus multilocularis protein kinase shaggy 0.0149 0.0455 0.0735
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0174 0.0615 0.0955
Echinococcus granulosus Vam6:Vps39 protein 0.011 0.0204 0.033
Echinococcus multilocularis serine threonine protein kinase 0.0824 0.485 0.7841
Echinococcus multilocularis dual specificity 0.0159 0.0521 0.0842
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0289 0.1366 0.2208
Echinococcus granulosus casein kinase I delta 0.0129 0.0326 0.0527
Loa Loa (eye worm) SRC-1 0.0361 0.1834 0.1834
Loa Loa (eye worm) hypothetical protein 0.011 0.0204 0.0204
Trypanosoma cruzi rac serine-threonine kinase, putative 0.1029 0.6185 1
Entamoeba histolytica hypothetical protein 0.0131 0.0341 0.0319
Echinococcus granulosus STE20 serine:threonine protein kinase 0.051 0.2808 0.4539
Trichomonas vaginalis CMGC family protein kinase 0.0163 0.0548 0.0522
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0131 0.0341 0.0336
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0679 0.3907 0.686
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0121 0.0276 0.0446
Echinococcus multilocularis protein kinase c eta type 0.0083 0.0023 0.0037
Loa Loa (eye worm) AGC/PKA protein kinase 0.0679 0.3907 0.3907
Trypanosoma brucei polo-like protein kinase 0.0289 0.1366 0.1342
Echinococcus multilocularis rho associated protein kinase 0.0343 0.1719 0.2779
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0247 0.1093 0.1767
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0163 0.0548 0.0846
Toxoplasma gondii aurora kinase 0.0166 0.0563 0.057
Trichomonas vaginalis AGC family protein kinase 0.1614 1 1
Loa Loa (eye worm) TK/FER protein kinase 0.0121 0.027 0.027
Loa Loa (eye worm) TK/FER protein kinase 0.0121 0.027 0.027
Echinococcus granulosus Diacylglycerol kinase theta 0.0083 0.0023 0.0037
Echinococcus granulosus N chimaerin 0.0152 0.0475 0.0768
Trichomonas vaginalis AGC family protein kinase 0.0131 0.0341 0.0314
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0165 0.0559 0.0903
Entamoeba histolytica PH domain containing protein kinase, putative 0.0131 0.0341 0.0319
Loa Loa (eye worm) AUR protein kinase 0.0166 0.0563 0.0563
Echinococcus granulosus epidermal growth factor receptor 0.0462 0.2494 0.4032
Echinococcus multilocularis protein kinase c iota type 0.0805 0.4725 0.764
Echinococcus multilocularis Rac GTPase activating protein 1 0.0083 0.0023 0.0037
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0679 0.3907 0.6317
Brugia malayi serine/threonine protein kinase 6 0.0166 0.0563 0.0563
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0205 0.0822 0.1329
Entamoeba histolytica cell division protein kinase 2, putative 0.0334 0.1661 0.1642
Trichomonas vaginalis CAMK family protein kinase 0.0121 0.0276 0.0249
Echinococcus multilocularis casein kinase I alpha 0.0129 0.0326 0.0527
Trichomonas vaginalis AGC family protein kinase 0.0166 0.0563 0.0537
Schistosoma mansoni tyrosine kinase 0.0091 0.0075 0.0122
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0614 0.3487 0.3487
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0241 0.1057 0.1708
Plasmodium vivax casein kinase 1, putative 0.0129 0.0326 0.0528
Trypanosoma cruzi Protein kinase B 0.1029 0.6185 1
Loa Loa (eye worm) hypothetical protein 0.0142 0.0409 0.0409
Echinococcus granulosus casein kinase I alpha 0.0129 0.0326 0.0527
Echinococcus granulosus tyrosine protein kinase Src64B 0.0361 0.1834 0.2965
Brugia malayi Fibronectin type III domain containing protein 0.0098 0.0123 0.0123
Plasmodium vivax calcium-dependent protein kinase, putative 0.0121 0.0276 0.0439
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0679 0.3907 0.389
Loa Loa (eye worm) TK/FER protein kinase 0.0121 0.027 0.027
Trypanosoma cruzi NIMA-related kinase, putative 0.0131 0.0341 0.0509
Schistosoma mansoni serine/threonine protein kinase 0.0235 0.1017 0.1644
Echinococcus multilocularis mitogen activated protein kinase 14 0.0179 0.0651 0.1052
Loa Loa (eye worm) TK/EPH protein kinase 0.0132 0.0343 0.0343
Brugia malayi diacylglycerol kinase 0.0083 0.0023 0.0023
Entamoeba histolytica protein kinase, putative 0.0124 0.0292 0.0269
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0897 0.5329 0.8616
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0083 0.0028 0.0005
Loa Loa (eye worm) CAMK/PIM protein kinase 0.037 0.1895 0.1895
Schistosoma mansoni serine/threonine protein kinase 0.0679 0.3907 0.6317
Brugia malayi p70 ribosomal S6 kinase beta 0.1537 0.9498 0.9498
Schistosoma mansoni rap gtpase-activating protein 0.011 0.0204 0.033
Loa Loa (eye worm) hypothetical protein 0.0237 0.1028 0.1028
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0163 0.0548 0.1342
Giardia lamblia Kinase, CMGC MAPK 0.0163 0.0548 0.0921
Loa Loa (eye worm) hypothetical protein 0.0206 0.0824 0.0824
Loa Loa (eye worm) raf kinase 0.0083 0.0023 0.0023
Schistosoma mansoni protein kinase C mu 0.0083 0.0023 0.0037
Trichomonas vaginalis CAMK family protein kinase 0.011 0.0202 0.0175
Plasmodium vivax serine/threonine kinase-1, putative 0.0174 0.0615 0.1039
Schistosoma mansoni vesicular amine transporter 0.0082 0.0022 0.0035
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0411 0.2163 0.3497
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0465 0.2513 0.2513
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0082 0.0022 0.0035
Echinococcus granulosus CDC7 cell division cycle 7 0.011 0.0205 0.033
Echinococcus granulosus mitogen activated protein kinase 11 0.0179 0.0651 0.1052
Plasmodium falciparum calcium-dependent protein kinase 5 0.0121 0.0276 0.0439
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0124 0.0292 0.0269
Brugia malayi Casein kinase II, alpha chain 0.0424 0.2249 0.2249
Trichomonas vaginalis CK1 family protein kinase 0.0129 0.0326 0.0299
Echinococcus granulosus tyrosine protein kinase shark 0.0331 0.1644 0.2658
Trichomonas vaginalis CMGC family protein kinase 0.0159 0.0521 0.0495
Loa Loa (eye worm) hypothetical protein 0.0101 0.0141 0.0141
Schistosoma mansoni tyrosine kinase 0.0325 0.1601 0.2588
Schistosoma mansoni serine/threonine protein kinase 0.013 0.0334 0.0541
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0606 0.3432 0.3414
Schistosoma mansoni tyrosine kinase 0.0174 0.0617 0.0997
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0152 0.0473 0.0446
Trichomonas vaginalis AGC family protein kinase 0.0152 0.0473 0.0446
Schistosoma mansoni serine/threonine protein kinase 0.0155 0.0495 0.08
Entamoeba histolytica PH domain containing protein kinase, putative 0.0756 0.4409 0.4396
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0174 0.0615 0.0955
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0123 0.0284 0.0459
Brugia malayi Temporarily assigned gene name protein 59 0.011 0.0204 0.0204
Brugia malayi Protein kinase domain containing protein 0.0135 0.0361 0.0361
Brugia malayi Variant SH3 domain containing protein 0.0156 0.0504 0.0504
Echinococcus granulosus protein kinase C gamma type 0.0824 0.485 0.7841
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0166 0.0563 0.0541
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0165 0.0558 0.0902
Entamoeba histolytica protein kinase , putative 0.0166 0.0563 0.0541
Trypanosoma cruzi SNF1-related protein kinases, putative 0.011 0.0202 0.0284
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0092 0.0087 0.014
Schistosoma mansoni serine/threonine protein kinase 0.0906 0.5387 0.8711
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.064 0.3654 0.5908
Schistosoma mansoni serine/threonine protein kinase 0.0155 0.0493 0.0797
Schistosoma mansoni hypothetical protein 0.0101 0.0141 0.0227
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0174 0.0615 0.0955
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0131 0.0341 0.0314
Plasmodium vivax unspecified product 0.0424 0.2249 0.3928
Leishmania major protein kinase, putative 0.0105 0.0172 0.0372
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0123 0.0284 0.0284
Schistosoma mansoni protein kinase 0.0259 0.1172 0.1895
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0135 0.0367 0.0594
Onchocerca volvulus 0.0137 0.0378 0.1147
Echinococcus multilocularis CDC7 cell division cycle 7 0.011 0.0205 0.033
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0104 0.0162 0.0147
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0679 0.3907 0.389
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.013 0.0333 0.0539
Trichomonas vaginalis CMGC family protein kinase 0.0163 0.0548 0.0522
Schistosoma mansoni serine/threonine protein kinase 0.0906 0.5387 0.8711
Echinococcus multilocularis myosin iiia 0.0105 0.0172 0.0277
Echinococcus granulosus casein kinase ii subunit beta 0.0083 0.0028 0.0044
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.064 0.3654 0.5908
Brugia malayi Protein kinase c protein 2 0.032 0.1572 0.1572
Trichomonas vaginalis CMGC family protein kinase 0.0159 0.0521 0.0495
Loa Loa (eye worm) hypothetical protein 0.022 0.0916 0.0916
Leishmania major protein kinase A catalytic subunit isoform 2 0.0679 0.3907 1
Echinococcus granulosus rho-associated protein kinase 1 0.0343 0.1719 0.2779
Schistosoma mansoni tyrosine kinase 0.0262 0.1191 0.1926
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.013 0.0333 0.0539
Brugia malayi ephrin receptor 1 precursor 0.0081 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0141 0.0404 0.0404
Trypanosoma cruzi cdc2-related kinase 3 0.0334 0.1661 0.2653
Schistosoma mansoni diacylglycerol kinase theta 0.0083 0.0023 0.0037
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0131 0.0341 0.0509
Brugia malayi Protein kinase domain containing protein 0.0384 0.1987 0.1987
Echinococcus multilocularis casein kinase I delta 0.0129 0.0326 0.0527
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0222 0.0931 0.0931
Brugia malayi Tyrosine-protein kinase abl-1 0.0127 0.0309 0.0309
Onchocerca volvulus 0.0091 0.0079 0.017
Echinococcus granulosus dual specificity 0.0159 0.0521 0.0842
Schistosoma mansoni serine/threonine protein kinase 0.0134 0.0356 0.0575
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0149 0.0455 0.0456
Onchocerca volvulus 0.0121 0.027 0.0795
Trichomonas vaginalis STE family protein kinase 0.0107 0.018 0.0153
Schistosoma mansoni serine/threonine protein kinase 0.064 0.3654 0.5908
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0174 0.0617 0.0997
Echinococcus multilocularis casein kinase I gamma 0.0232 0.0999 0.1615
Schistosoma mansoni kinase 0.0307 0.1484 0.24
Schistosoma mansoni serine/threonine protein kinase 0.0104 0.0162 0.0261
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0897 0.5329 0.8616
Trichomonas vaginalis CK1 family protein kinase 0.0129 0.0326 0.0299
Echinococcus multilocularis cyclin dependent kinase 1 0.0334 0.1661 0.2685
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0102 0.0151 0.0151
Brugia malayi cell division control protein 2 homolog 0.0334 0.1661 0.1661
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.022 0.0919 0.0919
Echinococcus granulosus serine:threonine protein kinase 3 0.0275 0.1279 0.2068
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.011 0.0204 0.033
Giardia lamblia Kinase, CMGC DYRK 0.0159 0.0521 0.0873
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0283 0.1327 0.2146
Echinococcus multilocularis tyrosine protein kinase 0.0288 0.136 0.2199
Plasmodium falciparum glycogen synthase kinase 3 0.0149 0.0455 0.0755
Loa Loa (eye worm) hypothetical protein 0.0083 0.0026 0.0026
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0212 0.0867 0.0867
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0083 0.0023 0.0023
Echinococcus multilocularis casein kinase i 0.0129 0.0326 0.0527
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0952 0.5683 0.9188
Trichomonas vaginalis AGC family protein kinase 0.0152 0.0473 0.0446
Echinococcus granulosus cGMP dependent protein kinase 1 0.0155 0.0493 0.0797
Echinococcus granulosus titin 0.0091 0.0079 0.0128
Entamoeba histolytica protein kinase, putative 0.0131 0.0341 0.0319
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0163 0.0548 0.0846
Schistosoma mansoni serine/threonine protein kinase 0.0241 0.1057 0.1708
Onchocerca volvulus 0.0511 0.2815 0.9125
Trypanosoma cruzi NIMA-related kinase, putative 0.0131 0.0341 0.0509
Echinococcus multilocularis tyrosine protein kinase HCK 0.0238 0.1035 0.1673
Entamoeba histolytica PH domain containing protein kinase, putative 0.0756 0.4409 0.4396
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0159 0.0521 0.0521
Loa Loa (eye worm) hypothetical protein 0.0137 0.0378 0.0378
Schistosoma mansoni unc-13 (munc13) 0.0092 0.0087 0.014
Brugia malayi Pleckstrin Homology Domain 0.016 0.0525 0.0525
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0259 0.1172 0.1895
Giardia lamblia Kinase, NEK 0.0156 0.0503 0.084
Entamoeba histolytica protein kinase, putative 0.0131 0.0341 0.0319
Plasmodium falciparum calcium-dependent protein kinase 2 0.0121 0.0276 0.0439
Trichomonas vaginalis AGC family protein kinase 0.0152 0.0473 0.0446
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0334 0.1661 0.1661
Loa Loa (eye worm) RasGEF domain-containing protein 0.0083 0.0023 0.0023
Loa Loa (eye worm) AGC/AKT protein kinase 0.1614 1 1
Giardia lamblia Kinase, CDC7 0.011 0.0205 0.0313
Loa Loa (eye worm) hypothetical protein 0.0369 0.189 0.189
Echinococcus multilocularis rac serine:threonine kinase 0.1029 0.6185 1
Trichomonas vaginalis CAMK family protein kinase 0.0289 0.1366 0.1342
Onchocerca volvulus 0.011 0.0205 0.0579
Entamoeba histolytica serine/threonine protein kinase, putative 0.0289 0.1366 0.1346
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0174 0.0615 0.0589
Echinococcus granulosus tyrosine protein kinase Fyn 0.0361 0.1834 0.2965
Leishmania major protein kinase, putative 0.0131 0.0341 0.0808
Trichomonas vaginalis CAMK family protein kinase 0.0289 0.1366 0.1342
Entamoeba histolytica protein kinase domain containing protein 0.0424 0.2249 0.2231
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0082 0.0022 0.0035
Loa Loa (eye worm) hypothetical protein 0.0083 0.0023 0.0023
Brugia malayi SH2 domain containing protein 0.042 0.2222 0.2222
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.011 0.0202 0.0175
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0163 0.0548 0.1342
Entamoeba histolytica hypothetical protein 0.013 0.0333 0.0311
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.011 0.0202 0.0309
Echinococcus granulosus mitogen activated protein kinase 14 0.0179 0.0651 0.1052
Echinococcus granulosus tyrosine kinase 0.0307 0.1487 0.2405
Schistosoma mansoni serine/threonine kinase 0.064 0.3654 0.5908
Echinococcus multilocularis serine:threonine protein kinase 0.0135 0.0361 0.0584
Schistosoma mansoni tyrosine kinase 0.0274 0.1268 0.205
Trypanosoma cruzi casein kinase, putative 0.0129 0.0326 0.0485
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0166 0.0563 0.091
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0334 0.1661 0.1661
Schistosoma mansoni serine/threonine protein kinase 0.0184 0.0683 0.1104
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0083 0.0028 0.0005
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0149 0.0455 0.0735
Echinococcus multilocularis growth factor receptor bound protein 2 0.0123 0.0284 0.0459
Trichomonas vaginalis STE family protein kinase 0.0105 0.0172 0.0144
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.0079 0.0128
Echinococcus multilocularis Pleckstrin y 0.0083 0.0026 0.0042
Schistosoma mansoni hypothetical protein 0.0083 0.0023 0.0037
Echinococcus multilocularis dual specificity 0.0159 0.0521 0.0842
Echinococcus granulosus nervana 2 0.0897 0.5329 0.8616
Giardia lamblia Kinase, AGC PKA 0.0679 0.3907 0.686
Schistosoma mansoni serine/threonine protein kinase 0.0968 0.5789 0.9361
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0129 0.0326 0.0326
Schistosoma mansoni tyrosine kinase 0.0274 0.1268 0.205
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0163 0.0548 0.0548
Trichomonas vaginalis AGC family protein kinase 0.0152 0.0473 0.0446
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0329 0.1628 0.1628
Giardia lamblia Kinase, NEK 0.0156 0.0503 0.084
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0334 0.1661 0.2685
Onchocerca volvulus Serine\/threonine kinase homolog 0.0289 0.1366 0.4381
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0131 0.0341 0.0314
Entamoeba histolytica protein kinase, putative 0.0092 0.0083 0.006
Loa Loa (eye worm) hypothetical protein 0.016 0.0525 0.0525
Brugia malayi RhoGEF domain containing protein 0.0083 0.0023 0.0023
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.013 0.0333 0.0539
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0135 0.0361 0.0361
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0092 0.0083 0.0133
Trichomonas vaginalis CAMK family protein kinase 0.0135 0.0361 0.0334
Schistosoma mansoni serine/threonine protein kinase 0.0289 0.1366 0.2208
Loa Loa (eye worm) hypothetical protein 0.0147 0.044 0.044
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0155 0.0493 0.0797
Loa Loa (eye worm) hypothetical protein 0.0083 0.0023 0.0023
Echinococcus granulosus growth factor receptor bound protein 2 0.0125 0.0297 0.048
Schistosoma mansoni serine/threonine protein kinase 0.0411 0.2163 0.3497
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0109 0.0197 0.0197
Plasmodium falciparum casein kinase 2, alpha subunit 0.0424 0.2249 0.3928
Brugia malayi phosphoinositide-dependent protein kinase I 0.0102 0.0151 0.0151
Echinococcus multilocularis titin 0.0091 0.0079 0.0128
Loa Loa (eye worm) casein kinase 0.0178 0.0645 0.0645
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0149 0.0455 0.1101
Echinococcus granulosus serine:threonine protein kinase N2 0.029 0.1373 0.2219
Loa Loa (eye worm) hypothetical protein 0.0083 0.0023 0.0023
Trypanosoma cruzi aurora B kinase, putative 0.0166 0.0563 0.087
Echinococcus granulosus calcium activated potassium channel 0.0155 0.0495 0.0799
Trichomonas vaginalis AGC family protein kinase 0.0156 0.0503 0.0477
Loa Loa (eye worm) hypothetical protein 0.0256 0.1154 0.1154
Giardia lamblia Kinase, NEK 0.0156 0.0503 0.084
Schistosoma mansoni serine/threonine protein kinase 0.0232 0.0999 0.1615
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0107 0.018 0.0291
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0325 0.1601 0.2588
Schistosoma mansoni tyrosine kinase 0.0274 0.1268 0.205
Onchocerca volvulus 0.0343 0.1719 0.5536
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0129 0.0326 0.0326
Brugia malayi Protein kinase domain containing protein 0.0288 0.136 0.136
Schistosoma mansoni serine/threonine protein kinase 0.013 0.0334 0.0541
Schistosoma mansoni tyrosine kinase 0.0462 0.2494 0.4032
Plasmodium vivax glycogen synthase kinase 3, putative 0.0149 0.0455 0.0755
Trichomonas vaginalis CAMK family protein kinase 0.0289 0.1366 0.1342
Trichomonas vaginalis AGC family protein kinase 0.0152 0.0473 0.0446
Schistosoma mansoni serine/threonine kinase 0.0236 0.1023 0.1654
Trichomonas vaginalis AGC family protein kinase 0.1614 1 1
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0102 0.0151 0.0244
Trichomonas vaginalis AGC family protein kinase 0.0152 0.0473 0.0446
Plasmodium vivax serine/threonine protein kinase, putative 0.0104 0.0162 0.0237
Schistosoma mansoni nck2/grb4 0.0123 0.0284 0.0459
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0251 0.112 0.112
Plasmodium vivax protein kinase Crk2 0.0334 0.1661 0.2888
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0361 0.1834 0.2965
Echinococcus multilocularis nervana 2 0.0897 0.5329 0.8616
Echinococcus multilocularis mitogen activated protein kinase 11 0.0179 0.0651 0.1052
Brugia malayi hypothetical protein 0.0241 0.1057 0.1057
Echinococcus granulosus serine:threonine protein kinase 0.0135 0.0361 0.0584
Loa Loa (eye worm) hypothetical protein 0.0119 0.0262 0.0262
Brugia malayi Protein kinase domain 0.0107 0.018 0.018
Plasmodium falciparum protein kinase 5 0.0334 0.1661 0.2888
Leishmania major serine/threonine-protein kinase a, putative 0.0131 0.0341 0.0808
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0235 0.1017 0.1644
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0295 0.1408 0.2276
Echinococcus granulosus tyrosine protein kinase 0.0288 0.136 0.2199
Trichomonas vaginalis CAMK family protein kinase 0.011 0.0202 0.0175
Trypanosoma cruzi casein kinase, putative 0.0129 0.0326 0.0485
Schistosoma mansoni serine/threonine protein kinase 0.0163 0.0548 0.0886
Brugia malayi Egg laying defective protein 4 0.0155 0.0493 0.0493
Entamoeba histolytica serine/threonine protein kinase, putative 0.011 0.0202 0.018
Entamoeba histolytica protein kinase, putative 0.0131 0.034 0.0318
Loa Loa (eye worm) TK protein kinase 0.0288 0.136 0.136
Echinococcus granulosus tyrosine protein kinase Lyn 0.0415 0.2188 0.3537
Echinococcus granulosus casein kinase ii subunit alpha 0.0424 0.2249 0.3636
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0131 0.0341 0.0509
Trichomonas vaginalis CMGC family protein kinase 0.0424 0.2249 0.2228
Trichomonas vaginalis AGC family protein kinase 0.0152 0.0473 0.0446
Echinococcus granulosus serine:threonine protein kinase N2 0.0768 0.4488 0.7257
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0241 0.1057 0.1057
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.051 0.2808 0.4539
Brugia malayi intracellular kinase 0.0149 0.0455 0.0455
Loa Loa (eye worm) AGC/NDR protein kinase 0.064 0.3654 0.3654
Echinococcus granulosus tyrosine protein kinase Blk 0.0307 0.1487 0.2405
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0121 0.0276 0.0276
Trichomonas vaginalis AGC family protein kinase 0.0152 0.0473 0.0446
Trichomonas vaginalis AGC family protein kinase 0.1614 1 1
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0361 0.1834 0.2965
Echinococcus multilocularis NCK adaptor protein 0.0125 0.0297 0.048
Onchocerca volvulus Tyrosine kinase homolog 0.0552 0.3082 1
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0334 0.1661 0.1661
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0083 0.0028 0.0005
Echinococcus granulosus casein kinase I alpha 0.0129 0.0326 0.0527
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0092 0.0087 0.014
Brugia malayi Protein kinase domain containing protein 0.0083 0.0025 0.0025
Trichomonas vaginalis CMGC family protein kinase 0.0159 0.0521 0.0495
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.011 0.0202 0.0202
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0278 0.1296 0.1296
Trypanosoma cruzi cdc2-related kinase 1 0.0334 0.1661 0.2653
Echinococcus multilocularis raf serine:threonine protein kinase 0.0134 0.0356 0.0575
Loa Loa (eye worm) hypothetical protein 0.0137 0.0378 0.0378
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0171 0.0597 0.0597
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0121 0.027 0.0248
Schistosoma mansoni serine/threonine protein kinase 0.064 0.3654 0.5908
Loa Loa (eye worm) hypothetical protein 0.011 0.0204 0.0204
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0082 0.0022 0.0035
Brugia malayi Protein kinase domain containing protein 0.0193 0.0741 0.0741
Loa Loa (eye worm) CAMK/PIM protein kinase 0.037 0.1895 0.1895
Trypanosoma brucei protein kinase, putative 0.0105 0.0172 0.0145
Echinococcus multilocularis tyrosine protein kinase shark 0.0331 0.1644 0.2658
Brugia malayi Protein kinase domain containing protein 0.064 0.3654 0.3654
Brugia malayi casein kinase I 0.0129 0.0326 0.0326
Trichomonas vaginalis CMGC family protein kinase 0.0424 0.2249 0.2228
Echinococcus granulosus epidermal growth factor receptor 0.0325 0.1601 0.2588
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0205 0.0177
Entamoeba histolytica PH domain containing protein kinase, putative 0.1029 0.6185 0.6176
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0121 0.0276 0.0446
Leishmania major protein kinase, putative 0.0121 0.0276 0.064
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0283 0.1327 0.1327
Schistosoma mansoni protein kinase 0.0173 0.0612 0.099
Brugia malayi Ras association domain family 1 isoform A 0.0083 0.0023 0.0023
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0121 0.0276 0.0439
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0205 0.0177
Loa Loa (eye worm) hypothetical protein 0.0614 0.3487 0.3487
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0143 0.0413 0.0627
Brugia malayi Protein kinase domain containing protein 0.0121 0.027 0.027
Plasmodium falciparum serine/threonine protein kinase 0.0104 0.0162 0.0237
Giardia lamblia Kinase, AGC AKT 0.0137 0.038 0.0623
Schistosoma mansoni serine/threonine-protein kinase 0.1029 0.6185 1
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0156 0.0503 0.0507
Brugia malayi RhoGAP domain containing protein 0.0083 0.0023 0.0023
Echinococcus multilocularis tyrosine kinase 0.0121 0.027 0.0437
Echinococcus granulosus c-Jun N-terminal kinases 0.0283 0.1327 0.2146
Brugia malayi Furin-like cysteine rich region family protein 0.0462 0.2494 0.2494
Echinococcus multilocularis ephrin type A receptor 4 A 0.0114 0.023 0.0371
Echinococcus granulosus protein kinase 0.0173 0.0612 0.099
Trichomonas vaginalis CAMK family protein kinase 0.0147 0.044 0.0414
Brugia malayi Protein kinase domain containing protein 0.0212 0.0867 0.0867
Entamoeba histolytica protein kinase domain containing protein 0.0143 0.0413 0.0391
Giardia lamblia Kinase, CMGC CK2 0.0424 0.2249 0.3928
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0159 0.0521 0.0495
Schistosoma mansoni serine/threonine protein kinase 0.0343 0.1719 0.2779
Brugia malayi protein-tyrosine kinase 0.0307 0.1487 0.1487
Entamoeba histolytica protein kinase, putative 0.1614 1 1
Entamoeba histolytica protein kinase, putative 0.0166 0.0563 0.0541
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0155 0.0493 0.0797
Mycobacterium ulcerans hypothetical protein 0.01 0.0139 0.5
Echinococcus multilocularis calcium activated potassium channel 0.0155 0.0495 0.0799
Giardia lamblia Kinase, CAMK CAMKL 0.011 0.0202 0.0309
Plasmodium falciparum serine/threonine protein kinase, putative 0.0166 0.0563 0.0947
Echinococcus multilocularis PAK box P21 Rho binding 0.0085 0.0041 0.0066
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0184 0.0683 0.1103
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0104 0.0162 0.0218
Echinococcus multilocularis neuroglian 0.0104 0.0161 0.0261
Entamoeba histolytica hypothetical protein 0.0143 0.0413 0.0391
Brugia malayi serine/threonine-protein kinase PAK 7 0.0251 0.112 0.112
Brugia malayi diacylglycerol kinase 0.0083 0.0023 0.0023
Echinococcus multilocularis dual specificity 0.0159 0.0521 0.0842
Trichomonas vaginalis CMGC family protein kinase 0.0334 0.1661 0.1638
Echinococcus granulosus tyrosine protein kinase Fyn 0.0361 0.1834 0.2965
Schistosoma mansoni serine/threonine protein kinase 0.0143 0.0413 0.0668
Loa Loa (eye worm) hypothetical protein 0.0082 0.0022 0.0022
Schistosoma mansoni serine/threonine protein kinase 0.011 0.0202 0.0327
Trichomonas vaginalis AGC family protein kinase 0.0152 0.0473 0.0446
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0131 0.0341 0.0554
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0679 0.3907 0.6317
Brugia malayi Variant SH3 domain containing protein 0.0123 0.0284 0.0284
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0952 0.5683 0.9188
Brugia malayi map kinase activated protein kinase protein 2 0.0411 0.2163 0.2163
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0166 0.0563 0.0541
Echinococcus multilocularis pdz domain containing protein 0.0092 0.0084 0.0136
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0105 0.0172 0.0234
Loa Loa (eye worm) hypothetical protein 0.0369 0.189 0.189
Echinococcus multilocularis myotubularin protein 13 0.016 0.0525 0.0848
Loa Loa (eye worm) hypothetical protein 0.0122 0.0279 0.0279
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0625 0.3553 0.5744
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0615 0.0995
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0205 0.0177
Schistosoma mansoni tyrosine kinase 0.0402 0.2104 0.3402
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.0083 0.0134
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0163 0.0548 0.0522
Trichomonas vaginalis AGC family protein kinase 0.0102 0.0151 0.0124
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0121 0.0276 0.0267
Schistosoma mansoni protein kinase 0.0166 0.0563 0.091
Echinococcus granulosus tyrosine protein kinase Srms 0.0523 0.2893 0.4678
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0906 0.5387 0.8711
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0289 0.1366 0.1366
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.066 0.3786 0.3786
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0241 0.1057 0.1708
Loa Loa (eye worm) TK/INSR protein kinase 0.0402 0.2104 0.2104
Entamoeba histolytica protein kinase domain containing protein 0.0222 0.0931 0.091
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0723 0.4195 0.4195
Schistosoma mansoni serine/threonine protein kinase 0.022 0.0919 0.1485
Echinococcus granulosus insulin receptor 0.0402 0.2104 0.3402
Brugia malayi probable protein kinase 0.0283 0.1331 0.1331
Schistosoma mansoni protein kinase 0.0107 0.018 0.0292
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0166 0.0563 0.091
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0679 0.3907 0.6317
Loa Loa (eye worm) protein kinase domain-containing protein 0.0232 0.0999 0.0999
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0165 0.0558 0.0902
Trypanosoma cruzi cdc2-related kinase 3 0.0334 0.1661 0.2653
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0105 0.0172 0.0145
Loa Loa (eye worm) hypothetical protein 0.0083 0.0024 0.0024
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0131 0.0341 0.0509
Brugia malayi Protein kinase domain containing protein 0.0143 0.0413 0.0413
Echinococcus granulosus tyrosine protein kinase HCK 0.0238 0.1035 0.1673
Schistosoma mansoni serine/threonine protein kinase 0.0155 0.0493 0.0797
Brugia malayi Temporarily assigned gene name protein 59 0.0127 0.0315 0.0315
Trichomonas vaginalis CAMK family protein kinase 0.011 0.0202 0.0175
Giardia lamblia Kinase, CAMK CAMKL 0.011 0.0202 0.0309
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0384 0.1987 0.3212
Onchocerca volvulus 0.0224 0.0942 0.2992
Echinococcus granulosus myotubularin protein 13 0.016 0.0525 0.0848
Entamoeba histolytica hypothetical protein 0.0131 0.0341 0.0319
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0679 0.3907 0.4099
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0121 0.0276 0.0276
Leishmania major folate/biopterin transporter, putative 0.0131 0.0341 0.0808
Echinococcus granulosus fibroblast growth factor receptor 4 0.0247 0.1093 0.1767
Schistosoma mansoni vav2 0.0229 0.0977 0.158
Loa Loa (eye worm) TK/FER protein kinase 0.0121 0.027 0.027
Schistosoma mansoni rac gtpase activating protein 0.0083 0.0023 0.0037
Loa Loa (eye worm) hypothetical protein 0.0141 0.0404 0.0404
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0307 0.1487 0.2405
Schistosoma mansoni serine/threonine protein kinase 0.0235 0.1017 0.1644
Echinococcus granulosus casein kinase I gamma 0.0232 0.0999 0.1615
Loa Loa (eye worm) hypothetical protein 0.0092 0.0087 0.0087
Trichomonas vaginalis CMGC family protein kinase 0.0424 0.2249 0.2228
Loa Loa (eye worm) TK protein kinase 0.0238 0.1035 0.1035
Loa Loa (eye worm) hypothetical protein 0.0088 0.0059 0.0059
Echinococcus granulosus activin receptor type 0.0105 0.0172 0.0277
Leishmania major protein kinase A catalytic subunit 0.0679 0.3907 1
Trypanosoma cruzi casein kinase, putative 0.0129 0.0326 0.0485
Toxoplasma gondii AGC kinase 0.1537 0.9498 1
Loa Loa (eye worm) Csnk2b protein 0.0083 0.0028 0.0028
Loa Loa (eye worm) CAMK/CAMKL/PASK protein kinase 0.0099 0.0129 0.0129
Brugia malayi Fes/CIP4 homology domain containing protein 0.0128 0.032 0.032
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.064 0.3654 0.5908
Echinococcus multilocularis cyclin dependent kinase 7 0.013 0.0334 0.054
Plasmodium falciparum protein kinase, putative 0.0105 0.0172 0.0255
Loa Loa (eye worm) hypothetical protein 0.0083 0.0023 0.0023
Trichomonas vaginalis STE family protein kinase 0.0107 0.018 0.0153
Brugia malayi Protein kinase domain containing protein 0.0334 0.1661 0.1661
Loa Loa (eye worm) hypothetical protein 0.0129 0.0328 0.0328
Brugia malayi Protein kinase domain containing protein 0.0184 0.0683 0.0683
Schistosoma mansoni tyrosine kinase 0.0174 0.0617 0.0997
Echinococcus granulosus dual specificity 0.0159 0.0521 0.0842
Giardia lamblia Kinase, AGC PKA 0.0952 0.5683 1
Trichomonas vaginalis CMGC family protein kinase 0.0334 0.1661 0.1638
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0163 0.0548 0.0846
Echinococcus multilocularis casein kinase I alpha 0.0129 0.0326 0.0527
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.045 0.2419 0.391
Plasmodium falciparum protein serine/threonine kinase-1 0.0174 0.0615 0.1039
Brugia malayi serine/threonine-protein kinase 6 0.0166 0.0563 0.0563
Echinococcus granulosus tyrosine kinase 0.0121 0.027 0.0437
Giardia lamblia Kinase, PLK 0.0289 0.1366 0.2366
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0334 0.1661 0.1729
Echinococcus multilocularis protein tyrosine kinase 0.0551 0.3074 0.497
Echinococcus multilocularis expressed protein 0.0104 0.0162 0.0261
Trichomonas vaginalis CAMK family protein kinase 0.0289 0.1366 0.1342
Echinococcus granulosus Immunoglobulin 0.0082 0.0022 0.0035
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0631 0.3597 0.3597
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.037 0.1895 0.6114
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.1537 0.9498 0.9498
Trichomonas vaginalis CK1 family protein kinase 0.0129 0.0326 0.0299
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0179 0.0651 0.1606
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1011 0.6068 0.9811
Schistosoma mansoni protein kinase 0.0107 0.018 0.0292
Trypanosoma brucei protein kinase, putative 0.0131 0.0341 0.0314
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0723 0.4195 0.6783
Onchocerca volvulus 0.0121 0.027 0.0795
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0952 0.5683 0.9185
Echinococcus multilocularis 0.0126 0.0304 0.0491
Schistosoma mansoni serine/threonine protein kinase 0.0679 0.3907 0.6317
Loa Loa (eye worm) hypothetical protein 0.0088 0.0059 0.0059
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0229 0.0977 0.158
Brugia malayi Protein kinase domain containing protein 0.0121 0.027 0.027
Trichomonas vaginalis AGC family protein kinase 0.0152 0.0473 0.0446
Echinococcus multilocularis mitogen activated protein kinase 14 0.0179 0.0651 0.1052
Onchocerca volvulus 0.0129 0.0326 0.0977
Echinococcus multilocularis serine:threonine protein kinase N2 0.0876 0.5188 0.8388
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0152 0.0475 0.0768
Brugia malayi Protein kinase domain containing protein 0.0121 0.027 0.027
Trichomonas vaginalis AGC family protein kinase 0.0131 0.0341 0.0314
Trichomonas vaginalis AGC family protein kinase 0.0152 0.0473 0.0446
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0174 0.0615 0.0955
Loa Loa (eye worm) hypothetical protein 0.011 0.0204 0.0204
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0152 0.0473 0.0446
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0174 0.0615 0.0615
Trypanosoma cruzi cdc2-related kinase 1 0.0334 0.1661 0.2653
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0105 0.0172 0.0149
Brugia malayi Protein kinase domain containing protein 0.0121 0.027 0.027
Trichomonas vaginalis CAMK family protein kinase 0.011 0.0202 0.0175
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0437 0.2333 0.3772
Echinococcus multilocularis casein kinase I alpha 0.0129 0.0326 0.0527
Entamoeba histolytica protein kinase, putative 0.0121 0.0276 0.0254
Echinococcus granulosus protein kinase c epsilon type 0.0968 0.5789 0.9361
Leishmania major protein kinase, putative 0.0131 0.0341 0.0808
Brugia malayi Protein kinase domain containing protein 0.0174 0.0615 0.0615
Trichomonas vaginalis AGC family protein kinase 0.0102 0.0151 0.0124
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0361 0.1834 0.2965
Loa Loa (eye worm) hypothetical protein 0.0229 0.0977 0.0977
Schistosoma mansoni serine/threonine protein kinase 0.0102 0.0151 0.0244
Schistosoma mansoni hypothetical protein 0.011 0.0204 0.033
Brugia malayi C1-like domain containing protein 0.0278 0.1296 0.1296
Echinococcus granulosus dual specificity 0.0159 0.0521 0.0842
Trichomonas vaginalis CMGC family protein kinase 0.0159 0.0521 0.0495
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0179 0.0651 0.1012
Loa Loa (eye worm) hypothetical protein 0.01 0.014 0.014
Brugia malayi P38 map kinase family protein 2 0.0179 0.0651 0.0651
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0102 0.0148 0.0132
Brugia malayi Protein kinase domain containing protein 0.066 0.3786 0.3786
Trichomonas vaginalis CAMK family protein kinase 0.011 0.0202 0.0175
Brugia malayi Protein kinase domain containing protein 0.0104 0.0162 0.0162
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0418 0.2205 0.3565
Brugia malayi protein kinase C3,putative 0.0219 0.091 0.091
Brugia malayi Protein kinase domain containing protein 0.037 0.1895 0.1895
Loa Loa (eye worm) CDC7 protein kinase 0.011 0.0205 0.0205
Schistosoma mansoni serine/threonine protein kinase 0.0295 0.1408 0.2276
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0149 0.0455 0.0455
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0159 0.0521 0.0526
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0149 0.0455 0.0735
Entamoeba histolytica protein kinase, putative 0.0104 0.0162 0.0139
Toxoplasma gondii CMGC kinase, CK2 family 0.0424 0.2249 0.235
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0129 0.0326 0.0326
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0679 0.3907 0.63
Schistosoma mansoni protein kinase 0.0085 0.0041 0.0066
Brugia malayi Kinase associated domain 1 family protein 0.0101 0.0141 0.0141
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0329 0.1628 0.1628
Echinococcus granulosus protein tyrosine kinase 0.0551 0.3074 0.497
Echinococcus granulosus mitogen activated protein kinase 3 0.0163 0.0548 0.0886
Echinococcus granulosus protein kinase c iota type 0.0805 0.4725 0.764
Schistosoma mansoni serine/threonine protein kinase 0.0159 0.0521 0.0843
Loa Loa (eye worm) AUR protein kinase 0.0166 0.0563 0.0563
Entamoeba histolytica PH domain containing protein kinase, putative 0.1029 0.6185 0.6176
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0334 0.1661 0.4211
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0361 0.1834 0.2965
Echinococcus granulosus Pleckstrin y 0.0083 0.0026 0.0042
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0105 0.0172 0.0234
Echinococcus multilocularis expressed conserved protein 0.0155 0.0493 0.0797
Trichomonas vaginalis CMGC family protein kinase 0.0424 0.2249 0.2228
Trichomonas vaginalis AGC family protein kinase 0.0152 0.0473 0.0446
Echinococcus granulosus casein kinase i 0.0129 0.0326 0.0527
Onchocerca volvulus 0.011 0.0205 0.0579
Loa Loa (eye worm) hypothetical protein 0.0224 0.0942 0.0942
Trichomonas vaginalis AGC family protein kinase 0.0166 0.0563 0.0537
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0195 0.0758 0.0758
Trichomonas vaginalis AGC family protein kinase 0.1614 1 1
Loa Loa (eye worm) TK/ABL protein kinase 0.0325 0.1605 0.1605
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0105 0.0172 0.0149
Echinococcus granulosus serine threonine protein kinase nrc 0.0952 0.5683 0.9188
Brugia malayi Serine/threonine-protein kinase Pim-3 0.037 0.1895 0.1895
Echinococcus multilocularis Glutaredoxin protein 5 0.0897 0.5329 0.8616
Entamoeba histolytica casein kinase, putative 0.0424 0.2249 0.2231
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0679 0.3907 0.6317
Loa Loa (eye worm) hypothetical protein 0.0777 0.4547 0.4547
Entamoeba histolytica protein kinase, putative 0.0085 0.0041 0.0018
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0679 0.3907 0.63
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.045 0.2419 0.391
Onchocerca volvulus 0.0121 0.027 0.0795
Trichomonas vaginalis CAMK family protein kinase 0.011 0.0202 0.0175
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.037 0.1895 0.3064
Brugia malayi Protein kinase domain containing protein 0.011 0.0205 0.0205
Schistosoma mansoni serine/threonine protein kinase 0.0768 0.4488 0.7257
Giardia lamblia Aurora kinase 0.0166 0.0563 0.0947
Loa Loa (eye worm) TK protein kinase 0.0351 0.177 0.177
Echinococcus multilocularis tyrosine protein kinase Blk 0.0307 0.1487 0.2405
Trichomonas vaginalis CAMK family protein kinase 0.0289 0.1366 0.1342
Trypanosoma brucei protein kinase, putative 0.0149 0.0455 0.0428
Schistosoma mansoni serine/threonine protein kinase 0.0723 0.4195 0.6783
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0129 0.0326 0.0485
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0152 0.0475 0.0768
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0166 0.0563 0.0541
Schistosoma mansoni tyrosine kinase 0.0551 0.3074 0.497
Loa Loa (eye worm) hypothetical protein 0.0137 0.0378 0.0378
Trypanosoma cruzi casein kinase, putative 0.0129 0.0326 0.0485
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0083 0.0023 0.0023
Echinococcus multilocularis aurora kinase A 0.0166 0.0563 0.091
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0679 0.3907 0.63
Loa Loa (eye worm) CAMK protein kinase 0.0091 0.0079 0.0079
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0149 0.0455 0.0735
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0815 0.4796 0.4796
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0679 0.3907 0.63
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0384 0.1987 0.1987
Brugia malayi serine/threonine-protein kinase plk-2 0.0289 0.1366 0.1366
Toxoplasma gondii histone kinase SNF1, putative 0.011 0.0202 0.0189
Brugia malayi Protein kinase domain containing protein 0.022 0.0919 0.0919
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0152 0.0475 0.0769
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.01 0.014 0.0225
Trichomonas vaginalis CAMK family protein kinase 0.011 0.0202 0.0175
Echinococcus granulosus aurora kinase A 0.0166 0.0563 0.091
Brugia malayi protein unc-22 0.0091 0.0079 0.0079
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0238 0.1034 0.1034
Echinococcus multilocularis RNA directed DNA polymerase 0.0174 0.0617 0.0997
Toxoplasma gondii ck2 beta subunit 0.0083 0.0028 0.0005
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0222 0.0931 0.0931
Brugia malayi Protein kinase domain containing protein 0.0465 0.2513 0.2513
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0092 0.0083 0.0133
Trichomonas vaginalis CMGC family protein kinase 0.0424 0.2249 0.2228
Entamoeba histolytica protein kinase, putative 0.0143 0.0413 0.0391
Loa Loa (eye worm) hypothetical protein 0.0118 0.025 0.025
Echinococcus granulosus NCK adaptor protein 0.0123 0.0284 0.0459
Brugia malayi SH2 domain containing protein 0.0121 0.027 0.027
Loa Loa (eye worm) TK/FER protein kinase 0.0121 0.027 0.027
Trichomonas vaginalis CAMK family protein kinase 0.0236 0.1023 0.0998
Loa Loa (eye worm) TK/FER protein kinase 0.0121 0.027 0.027
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0156 0.0504 0.0504
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0679 0.3907 0.389
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0679 0.3907 0.3907
Schistosoma mansoni adapter molecule crk 0.0123 0.0284 0.0459
Schistosoma mansoni cell adhesion molecule 0.0116 0.024 0.0389
Schistosoma mansoni serine/threonine protein kinase 0.011 0.0202 0.0327
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0107 0.018 0.0291
Loa Loa (eye worm) hypothetical protein 0.0098 0.0123 0.0123
Echinococcus multilocularis hypothetical protein 0.0101 0.0141 0.0227
Echinococcus granulosus tyrosine protein kinase ABL1 0.0325 0.1605 0.2594
Echinococcus multilocularis casein kinase ii subunit alpha 0.0424 0.2249 0.3636
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0131 0.0341 0.0509
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0235 0.1017 0.1644
Echinococcus multilocularis insulin receptor 0.0402 0.2104 0.3402
Entamoeba histolytica protein kinase, putative 0.0107 0.018 0.0158
Echinococcus multilocularis Immunoglobulin 0.0082 0.0022 0.0035
Echinococcus multilocularis 0.0173 0.0612 0.099
Schistosoma mansoni serine/threonine protein kinase 0.0283 0.1327 0.2146
Echinococcus granulosus expressed protein 0.0104 0.0162 0.0261
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0107 0.018 0.0291
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0131 0.0341 0.0509
Loa Loa (eye worm) hypothetical protein 0.0098 0.0123 0.0123
Entamoeba histolytica protein kinase, putative 0.0104 0.0162 0.0139
Loa Loa (eye worm) hypothetical protein 0.0083 0.0023 0.0023
Onchocerca volvulus 0.0092 0.0087 0.0194
Echinococcus multilocularis cyclin dependent kinase 1 0.0334 0.1661 0.2685
Schistosoma mansoni serine/threonine protein kinase 0.037 0.1895 0.3064
Schistosoma mansoni serine/threonine protein kinase 0.0679 0.3907 0.6317
Echinococcus granulosus titin 0.0091 0.0079 0.0128
Schistosoma mansoni tyrosine kinase 0.0386 0.1999 0.3233
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0105 0.0172 0.0234
Echinococcus multilocularis death associated protein kinase 1 0.086 0.5085 0.8222
Echinococcus granulosus cGMP dependent protein kinase 0.0155 0.0493 0.0797
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0334 0.1661 0.4211
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0143 0.0413 0.0995
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.011 0.0204 0.033
Giardia lamblia Kinase, CMGC SRPK 0.0104 0.0162 0.0237
Trypanosoma brucei protein kinase, putative 0.0163 0.0548 0.0522
Brugia malayi Immunoglobulin I-set domain containing protein 0.0091 0.0079 0.0079
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0295 0.1408 0.2276
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0424 0.2249 0.2249
Trichomonas vaginalis STE family protein kinase 0.0107 0.018 0.0153
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0952 0.5683 1
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0121 0.0276 0.0446
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0091 0.0079 0.0079
Brugia malayi Protein kinase domain containing protein 0.0102 0.0151 0.0151
Leishmania major protein kinase, putative 0.0174 0.0615 0.1515
Plasmodium falciparum casein kinase 1 0.0129 0.0326 0.0528
Echinococcus granulosus tyrosine protein kinase Src42A 0.0258 0.1168 0.1888
Brugia malayi SRC-1 0.0361 0.1834 0.1834
Echinococcus granulosus defective proboscis extension response 0.0082 0.0022 0.0035
Leishmania major protein kinase, putative 0.0105 0.0172 0.0371
Brugia malayi hypothetical protein 0.0121 0.027 0.027
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0361 0.1834 0.2965
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0679 0.3907 0.6317
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0289 0.1366 0.345
Giardia lamblia Kinase, CMGC CDK 0.0334 0.1661 0.2888
Echinococcus granulosus cyclin dependent kinase 1 0.0334 0.1661 0.2685
Echinococcus granulosus unc 13 munc13 0.0092 0.0087 0.014
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0105 0.0172 0.0234
Loa Loa (eye worm) hypothetical protein 0.0083 0.0023 0.0023
Echinococcus multilocularis mitogen activated protein kinase 11 0.0179 0.0651 0.1052
Echinococcus multilocularis tyrosine protein kinase Abl 0.0252 0.1127 0.1822
Echinococcus granulosus dual specificity 0.0143 0.0413 0.0668
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0131 0.0341 0.0509
Echinococcus granulosus serine:threonine protein kinase N2 0.0128 0.0319 0.0516
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0105 0.0172 0.0144
Trypanosoma brucei SNF1-related protein kinases, putative 0.011 0.0202 0.0175
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0121 0.0276 0.0446
Trichomonas vaginalis CMGC family protein kinase 0.0149 0.0455 0.0428
Trichomonas vaginalis CAMK family protein kinase 0.011 0.0202 0.0175
Brugia malayi Variant SH3 domain containing protein 0.0152 0.0475 0.0475
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0163 0.0548 0.0846
Schistosoma mansoni ephrin receptor 0.0114 0.023 0.0371
Schistosoma mansoni protein kinase 0.045 0.2419 0.3911
Brugia malayi Variant SH3 domain containing protein 0.0123 0.0284 0.0284
Brugia malayi hypothetical protein 0.011 0.0204 0.0204
Loa Loa (eye worm) hypothetical protein 0.0098 0.0123 0.0123
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0184 0.0683 0.0683
Entamoeba histolytica protein kinase domain containing protein 0.0166 0.0563 0.0541
Trichomonas vaginalis AGC family protein kinase 0.0166 0.0563 0.0537
Trichomonas vaginalis CAMK family protein kinase 0.011 0.0202 0.0175
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0131 0.0341 0.0314
Plasmodium falciparum calcium-dependent protein kinase 1 0.0121 0.0276 0.0439
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0121 0.0276 0.0276
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0258 0.1168 0.1888
Schistosoma mansoni protein kinase 0.0283 0.1331 0.2152
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0222 0.0931 0.1504
Echinococcus multilocularis serine:threonine kinase SAD 1 0.011 0.0202 0.0327
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.064 0.3654 0.5908
Echinococcus granulosus Protein kinase C brain isozyme 0.0906 0.5387 0.8711
Echinococcus granulosus twitchin 0.0158 0.0515 0.0833
Brugia malayi Protein kinase domain containing protein 0.0614 0.3487 0.3487
Trypanosoma brucei cdc2-related kinase 1 0.0334 0.1661 0.1638
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0679 0.3907 0.686
Onchocerca volvulus Serine\/threonine kinase homolog 0.0184 0.0683 0.2144
Plasmodium falciparum calcium-dependent protein kinase 3 0.0121 0.0276 0.0439
Loa Loa (eye worm) thyroid receptor interactor 0.0128 0.032 0.032
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0278 0.1296 0.1296
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0174 0.0615 0.0625
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0121 0.0276 0.0267
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0131 0.0341 0.0509
Leishmania major protein kinase, putative 0.0174 0.0615 0.1515
Brugia malayi Protein kinase domain containing protein 0.0557 0.3113 0.3113
Brugia malayi Protein kinase domain containing protein 0.0511 0.2815 0.2815
Trichomonas vaginalis AGC family protein kinase 0.0131 0.0341 0.0314
Brugia malayi Csnk2b protein 0.0083 0.0028 0.0028
Echinococcus granulosus mitogen activated protein kinase 0.0163 0.0548 0.0886
Giardia lamblia Kinase, STE STE20 0.0105 0.0172 0.0255
Loa Loa (eye worm) TK/FER protein kinase 0.0121 0.027 0.027
Leishmania major casein kinase II, putative 0.0424 0.2249 0.5727
Loa Loa (eye worm) hypothetical protein 0.0456 0.2454 0.2454
Giardia lamblia Kinase, CMGC CDK 0.0334 0.1661 0.2888
Schistosoma mansoni tyrosine kinase 0.0402 0.2104 0.3402
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0205 0.0822 0.0822
Trichomonas vaginalis STE family protein kinase 0.0107 0.018 0.0153
Schistosoma mansoni ste20-related kinase 0.0224 0.0947 0.1531
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0247 0.1093 0.1767
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0173 0.0612 0.0612
Brugia malayi serine/threonine kinase 12 0.0166 0.0563 0.0563
Echinococcus multilocularis dual specificity 0.0143 0.0413 0.0668
Echinococcus multilocularis dual specificity protein kinase clk2 0.0174 0.0615 0.0995
Trypanosoma cruzi casein kinase II, putative 0.0424 0.2249 0.3608
Entamoeba histolytica protein kinase domain containing protein 0.0105 0.0172 0.0149
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0155 0.0493 0.0496
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0131 0.0341 0.0509
Schistosoma mansoni serine/threonine protein kinase 0.0155 0.0495 0.08
Giardia lamblia Kinase, CK1 Casein kinase 0.0129 0.0326 0.0528
Loa Loa (eye worm) hypothetical protein 0.0174 0.0617 0.0617
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.042 0.2222 0.3593
Entamoeba histolytica casein kinase, putative 0.0129 0.0326 0.0304
Echinococcus granulosus nervana 2 0.0897 0.5329 0.8616
Brugia malayi MAP kinase sur-1 0.0163 0.0548 0.0548
Trypanosoma brucei aurora B kinase 0.0166 0.0563 0.0537
Onchocerca volvulus 0.0289 0.1365 0.4377
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0679 0.3907 0.6317
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0143 0.0413 0.0387
Brugia malayi Immunoglobulin I-set domain containing protein 0.0631 0.3597 0.3597
Schistosoma mansoni protein kinase 0.045 0.2419 0.3911
Entamoeba histolytica casein kinase 1, putative 0.0129 0.0326 0.0304
Schistosoma mansoni growth factor receptor-bound protein 0.0123 0.0284 0.0459
Schistosoma mansoni serine/threonine protein kinase 0.0121 0.0276 0.0446
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.022 0.0918 0.1485
Entamoeba histolytica protein kinase, putative 0.0131 0.0341 0.0319
Entamoeba histolytica protein kinase, putative 0.1614 1 1
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0121 0.0276 0.0439
Brugia malayi Cam kinase protein 1 0.0121 0.0276 0.0276
Loa Loa (eye worm) hypothetical protein 0.0123 0.0284 0.0284
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0102 0.0151 0.0244
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0236 0.1023 0.1023
Trichomonas vaginalis AGC family protein kinase 0.066 0.3786 0.3769
Loa Loa (eye worm) hypothetical protein 0.0301 0.1444 0.1444
Schistosoma mansoni hypothetical protein 0.0101 0.0141 0.0227
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0143 0.0413 0.0627
Trichomonas vaginalis AGC family protein kinase 0.0152 0.0473 0.0446
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0102 0.0151 0.0151
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0179 0.0651 0.1012
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.011 0.0202 0.045
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0123 0.0284 0.0284
Schistosoma mansoni titin 0.0091 0.0079 0.0128
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0411 0.2163 0.3497
Schistosoma mansoni serine/threonine protein kinase 0.0493 0.2696 0.4358
Trichomonas vaginalis AGC family protein kinase 0.0152 0.0473 0.0446
Echinococcus granulosus tyrosine protein kinase Fyn 0.0361 0.1834 0.2965
Trichomonas vaginalis STE family protein kinase 0.0085 0.0041 0.0013
Echinococcus granulosus dual specificity protein kinase clk2 0.0174 0.0615 0.0995
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0163 0.0548 0.0555
Trichomonas vaginalis CAMK family protein kinase 0.011 0.0202 0.0175
Echinococcus granulosus casein kinase I delta 0.0129 0.0326 0.0527
Echinococcus granulosus ephrin type A receptor 4 A 0.0114 0.023 0.0371
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0137 0.038 0.038
Schistosoma mansoni serine/threonine protein kinase 0.0274 0.1268 0.205
Loa Loa (eye worm) TK/FER protein kinase 0.0121 0.027 0.027
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0361 0.1834 0.2965
Trichomonas vaginalis CMGC family protein kinase 0.0424 0.2249 0.2228
Echinococcus multilocularis mitogen activated protein kinase 3 0.0163 0.0548 0.0886
Schistosoma mansoni serine/threonine-protein kinase 0.1029 0.6185 1
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0149 0.0455 0.0694
Brugia malayi Protein kinase domain containing protein 0.0402 0.2104 0.2104
Plasmodium falciparum cGMP-dependent protein kinase 0.0155 0.0493 0.0823
Echinococcus granulosus neuroglian 0.0104 0.0161 0.0261
Echinococcus granulosus cGMP dependent protein kinase 1 0.0155 0.0493 0.0797
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0159 0.0521 0.0521
Brugia malayi Protein kinase domain containing protein 0.0254 0.1142 0.1142
Loa Loa (eye worm) AGC/PKA protein kinase 0.0679 0.3907 0.3907
Entamoeba histolytica protein kinase, putative 0.0159 0.0521 0.0499
Toxoplasma gondii casein kinase I 0.0129 0.0326 0.032
Schistosoma mansoni protein kinase C mu 0.0278 0.1296 0.2095
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0179 0.0651 0.0625
Echinococcus multilocularis 0.0119 0.0262 0.0423
Schistosoma mansoni protein kinase 0.0212 0.0867 0.1403
Echinococcus granulosus RNA directed DNA polymerase 0.0174 0.0617 0.0997
Echinococcus granulosus casein kinase I alpha 0.0129 0.0326 0.0527
Echinococcus multilocularis roundabout 2 0.0137 0.038 0.0614
Schistosoma mansoni nephrin 0.0119 0.0262 0.0424
Trichomonas vaginalis CMGC family protein kinase 0.0174 0.0615 0.0589
Leishmania major protein kinase, putative 0.0166 0.0563 0.138
Trypanosoma cruzi polo-like protein kinase, putative 0.0289 0.1366 0.2173
Plasmodium falciparum NIMA related kinase 1 0.0156 0.0503 0.084
Trichomonas vaginalis STE family protein kinase 0.0156 0.0503 0.0477
Loa Loa (eye worm) TK/ALK protein kinase 0.0285 0.1339 0.1339
Entamoeba histolytica p21-activated kinase 0.0184 0.0682 0.0661
Entamoeba histolytica protein kinase domain containing protein 0.0159 0.0521 0.0499
Trichomonas vaginalis AGC family protein kinase 0.0152 0.0473 0.0446
Schistosoma mansoni serine/threonine protein kinase 0.0222 0.0931 0.1505
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0159 0.0521 0.1272
Echinococcus multilocularis protein kinase c epsilon type 0.0968 0.5789 0.9361
Echinococcus multilocularis N chimaerin 0.0152 0.0475 0.0768
Leishmania major protein kinase A catalytic subunit isoform 1 0.0679 0.3907 1
Echinococcus multilocularis epidermal growth factor receptor 0.0325 0.1601 0.2588
Schistosoma mansoni protein kinase 0.0259 0.1172 0.1895
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0152 0.0475 0.0769
Echinococcus multilocularis serine:threonine protein kinase N2 0.0768 0.4488 0.7257
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0166 0.0563 0.0947
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0131 0.0341 0.0808
Echinococcus granulosus protein kinase c eta type 0.0083 0.0023 0.0037
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0107 0.018 0.0291
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0437 0.2333 0.3772
Brugia malayi RhoGAP domain containing protein 0.0152 0.0475 0.0475
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0225 0.0949 0.0949
Trichomonas vaginalis AGC family protein kinase 0.1614 1 1
Entamoeba histolytica protein kinase, putative 0.0149 0.0455 0.0433
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0361 0.1834 0.2965
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0361 0.1834 0.2965
Loa Loa (eye worm) hypothetical protein 0.028 0.1307 0.1307
Trichomonas vaginalis CAMK family protein kinase 0.0147 0.044 0.0414
Loa Loa (eye worm) hypothetical protein 0.0122 0.0279 0.0279
Brugia malayi Protein kinase domain containing protein 0.0285 0.134 0.134
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.011 0.0204 0.0177
Loa Loa (eye worm) AUR protein kinase 0.0166 0.0563 0.0563
Brugia malayi cyclin-dependent kinase 7 homolog 0.013 0.0334 0.0334
Entamoeba histolytica protein kinase 2, putative 0.0952 0.5683 0.5673
Echinococcus granulosus c src tyrosine kinase 0.0174 0.0617 0.0997
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.011 0.0204 0.0287
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0121 0.0276 0.0249
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0361 0.1834 0.2965
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0325 0.1605 0.2594
Echinococcus granulosus NDR protein kinase 0.064 0.3654 0.5908
Onchocerca volvulus 0.011 0.0204 0.0577
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0174 0.0617 0.0997
Schistosoma mansoni protein kinase 0.045 0.2419 0.3911
Entamoeba histolytica protein kinase, putative 0.0162 0.0543 0.0521
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0247 0.1093 0.1767
Trichomonas vaginalis CMGC family protein kinase 0.0424 0.2249 0.2228
Loa Loa (eye worm) hypothetical protein 0.0121 0.0276 0.0276
Plasmodium vivax tyrosine kinase-like protein, putative 0.0102 0.0148 0.0213
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0361 0.1834 0.2965
Trichomonas vaginalis AGC family protein kinase 0.0166 0.0563 0.0537
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0307 0.1487 0.2405
Schistosoma mansoni tyrosine kinase 0.0247 0.1093 0.1768
Echinococcus granulosus pdz domain containing protein 0.0092 0.0084 0.0136
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.011 0.0202 0.0284
Schistosoma mansoni serine/threonine protein kinase 0.0334 0.1661 0.2686
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0174 0.0615 0.0589
Trichomonas vaginalis CAMK family protein kinase 0.011 0.0202 0.0175
Trichomonas vaginalis CMGC family protein kinase 0.0163 0.0548 0.0522
Echinococcus granulosus Rac GTPase activating protein 1 0.0083 0.0023 0.0037
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0424 0.2249 0.3928
Trichomonas vaginalis CAMK family protein kinase 0.011 0.0202 0.0175
Echinococcus granulosus tyrosine protein kinase Src42A 0.0361 0.1834 0.2965
Trichomonas vaginalis CAMK family protein kinase 0.011 0.0202 0.0175
Loa Loa (eye worm) hypothetical protein 0.011 0.0202 0.0202
Brugia malayi Sex muscle abnormal protein 5 0.0123 0.0284 0.0284
Echinococcus multilocularis Diacylglycerol kinase theta 0.0083 0.0023 0.0037
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0968 0.5789 0.5789
Entamoeba histolytica protein kinase, putative 0.0166 0.0563 0.0541
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0135 0.0367 0.0594
Loa Loa (eye worm) AGC/PKG protein kinase 0.0155 0.0493 0.0493
Giardia lamblia Kinase, CMGC GSK 0.0149 0.0455 0.0755
Onchocerca volvulus 0.048 0.261 0.8454
Schistosoma mansoni serine/threonine protein kinase 0.0334 0.1661 0.2686
Toxoplasma gondii protein kinase domain-containing protein 0.0131 0.0341 0.0336
Loa Loa (eye worm) IKK protein kinase 0.0511 0.2815 0.2815
Trypanosoma brucei cdc2-related kinase 3 0.0334 0.1661 0.1638
Brugia malayi Protein kinase domain containing protein 0.0232 0.0999 0.0999
Onchocerca volvulus 0.0121 0.027 0.0795
Schistosoma mansoni serine/threonine protein kinase 0.0135 0.0366 0.0592
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.011 0.0204 0.0287
Entamoeba histolytica protein kinase domain containing protein 0.0149 0.0455 0.0433
Schistosoma mansoni serine/threonine protein kinase 0.0155 0.0495 0.08
Brugia malayi Stress-activated protein kinase jnk-1 0.0283 0.1327 0.1327
Trypanosoma brucei rac serine-threonine kinase, putative 0.1614 1 1
Schistosoma mansoni tyrosine kinase 0.0361 0.1834 0.2965
Schistosoma mansoni serine/threonine protein kinase 0.011 0.0202 0.0327
Trichomonas vaginalis CAMK family protein kinase 0.011 0.0202 0.0175
Echinococcus multilocularis activin receptor type 0.0105 0.0172 0.0277
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0121 0.0276 0.0267
Trichomonas vaginalis AGC family protein kinase 0.066 0.3786 0.3769
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0952 0.5683 1
Entamoeba histolytica protein kinase, putative 0.1537 0.9498 0.9497
Giardia lamblia Kinase, CMGC CLK 0.0174 0.0615 0.1039
Brugia malayi Protein kinase domain containing protein 0.0614 0.3487 0.3487
Loa Loa (eye worm) TK/FAK protein kinase 0.0557 0.3113 0.3113
Loa Loa (eye worm) hypothetical protein 0.0135 0.0361 0.0361
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0222 0.0931 0.1504
Entamoeba histolytica PH domain containing protein kinase, putative 0.0367 0.1875 0.1856
Echinococcus multilocularis serine:threonine protein kinase 0.0135 0.0361 0.0584
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0105 0.0172 0.0157
Entamoeba histolytica cell division protein kinase 2, putative 0.0334 0.1661 0.1642
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0361 0.1834 0.2965
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0107 0.018 0.0291
Trypanosoma brucei Casein kinase II 0.0424 0.2249 0.2228
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0679 0.3907 0.6317
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0723 0.4195 0.6783
Loa Loa (eye worm) hypothetical protein 0.0679 0.3907 0.3907
Echinococcus granulosus roundabout 2 0.0137 0.038 0.0614
Echinococcus granulosus Glutaredoxin protein 5 0.0897 0.5329 0.8616
Loa Loa (eye worm) AGC/PKN protein kinase 0.0768 0.4488 0.4488
Schistosoma mansoni diacylglycerol kinase theta 0.0083 0.0023 0.0037
Brugia malayi hypothetical protein 0.0098 0.0123 0.0123
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0131 0.0341 0.0314
Echinococcus granulosus cyclin dependent kinase 5 0.0334 0.1661 0.2685
Loa Loa (eye worm) hypothetical protein 0.0121 0.027 0.027
Trichomonas vaginalis AGC family protein kinase 0.0737 0.4288 0.4272
Echinococcus multilocularis tyrosine protein kinase Srms 0.0307 0.1487 0.2405
Echinococcus multilocularis serine:threonine protein kinase 3 0.0275 0.1279 0.2068
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0107 0.018 0.0291
Echinococcus multilocularis cyclin dependent kinase 5 0.0334 0.1661 0.2685
Brugia malayi Immunoglobulin I-set domain containing protein 0.0268 0.1233 0.1233
Echinococcus multilocularis mitogen activated protein kinase 0.0163 0.0548 0.0886
Trichomonas vaginalis CMGC family protein kinase 0.0334 0.1661 0.1638
Schistosoma mansoni protein kinase 0.0129 0.0326 0.0527
Trichomonas vaginalis CMGC family protein kinase 0.0159 0.0521 0.0495
Schistosoma mansoni growth factor receptor-bound protein 0.0125 0.0297 0.048
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0235 0.1017 0.1644
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.011 0.0204 0.033

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 3.75 nM BindingDB_Patents: Enzyme Assay. Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat# 62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor sourced from Invitrogen (see table below). This activity-assay measures the phosphorylation of tyrosine residues within a substrate from the HTRF kit which has been validated by Cisbio for a variety of tyrosine kinases including the TRK receptors. Assay details: Target:TRKA; Invitrogen Cat# PV3144; Amino acids:aa 441-796; FAC enzyme:4nM; FAC ATP:40uM; Assay Reaction Time:35min. ChEMBL. No reference
IC50 (binding) = 3.75 nM Enzyme Assay BINDINGDB. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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