Detailed information for compound 252946

Basic information

Technical information
  • TDR Targets ID: 252946
  • Name: 4-(6-methoxy-7-prop-2-enoxyquinazolin-4-yl)-N -(4-phenoxyphenyl)piperazine-1-carboxamide
  • MW: 511.572 | Formula: C29H29N5O4
  • H donors: 1 H acceptors: 3 LogP: 4.77 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 2
  • SMILES: C=CCOc1cc2ncnc(c2cc1OC)N1CCN(CC1)C(=O)Nc1ccc(cc1)Oc1ccccc1
  • InChi: 1S/C29H29N5O4/c1-3-17-37-27-19-25-24(18-26(27)36-2)28(31-20-30-25)33-13-15-34(16-14-33)29(35)32-21-9-11-23(12-10-21)38-22-7-5-4-6-8-22/h3-12,18-20H,1,13-17H2,2H3,(H,32,35)
  • InChiKey: MPDJGCLHGADASW-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-(7-allyloxy-6-methoxy-quinazolin-4-yl)-N-(4-phenoxyphenyl)piperazine-1-carboxamide
  • 4-(7-allyloxy-6-methoxy-4-quinazolinyl)-N-(4-phenoxyphenyl)-1-piperazinecarboxamide
  • 4-(6-methoxy-7-prop-2-enoxy-quinazolin-4-yl)-N-(4-phenoxyphenyl)piperazine-1-carboxamide
  • 4-(6-methoxy-7-prop-2-enoxyquinazolin-4-yl)-N-[4-(phenoxy)phenyl]piperazine-1-carboxamide
  • 4-(7-allyloxy-6-methoxy-quinazolin-4-yl)-N-[4-(phenoxy)phenyl]piperazine-1-carboxamide
  • 4-(7-allyloxy-6-methoxy-4-quinazolinyl)-N-[4-(phenoxy)phenyl]-1-piperazinecarboxamide
  • 4-(6-methoxy-7-prop-2-enoxy-quinazolin-4-yl)-N-[4-(phenoxy)phenyl]piperazine-1-carboxamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens platelet-derived growth factor receptor, beta polypeptide Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0034 0.0071 0.041
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0013 0.001 0.0005
Mycobacterium tuberculosis Probable dehydrogenase 0.0321 0.0923 0.1399
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0156
Schistosoma mansoni aryl hydrocarbon receptor 0.0023 0.0039 0.0067
Echinococcus multilocularis serotonin receptor 0.0047 0.011 0.0106
Brugia malayi Serotonin receptor 0.0047 0.011 0.0675
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0041 0.0093 0.0547
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0058 0.0143 0.0271
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0047 0.011 0.0207
Onchocerca volvulus 0.0047 0.011 0.0719
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0047 0.011 0.0207
Entamoeba histolytica acyl-CoA synthetase, putative 0.0016 0.0018 0.005
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0013 0.001 0.0005
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0047 0.011 0.0106
Echinococcus granulosus tm gpcr rhodopsin 0.0047 0.011 0.0106
Loa Loa (eye worm) hypothetical protein 0.0019 0.0029 0.0149
Loa Loa (eye worm) RGS-3 protein 0.0013 0.0011 0.0041
Brugia malayi Steroid receptor seven-up type 2 0.0041 0.0093 0.0573
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0047 0.011 0.0675
Entamoeba histolytica phosphofructokinase, putative 0.015 0.0418 0.2357
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0048 0.0114 0.0605
Schistosoma mansoni neuropeptide f receptor 76f 0.0047 0.011 0.0207
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0024 0.0042 0.0073
Wolbachia endosymbiont of Brugia malayi recombinase A 0.0071 0.0182 0.2412
Mycobacterium ulcerans esterase/lipase LipP 0.0024 0.0042 0.0255
Echinococcus multilocularis neuroglian 0.0014 0.0013 0.0009
Loa Loa (eye worm) hypothetical protein 0.0013 0.0011 0.0041
Trichomonas vaginalis glutaminase, putative 0.0558 0.1629 0.9339
Trypanosoma cruzi pyruvate kinase 2, putative 0.0045 0.0104 0.0274
Schistosoma mansoni DNA polymerase eta 0.0013 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Schistosoma mansoni hypothetical protein 0.0346 0.0999 0.1952
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0678 0.3855
Trichomonas vaginalis PIKK family atypical protein kinase 0.0135 0.0373 0.2101
Loa Loa (eye worm) pyruvate kinase-PB 0.0031 0.0064 0.0364
Mycobacterium ulcerans acyl-CoA synthetase 0.0016 0.0018 0.0107
Echinococcus granulosus histone acetyltransferase KAT2B 0.0099 0.0265 0.0261
Toxoplasma gondii NADPH-glutathione reductase 0.0049 0.0116 0.1597
Entamoeba histolytica pyruvate kinase, putative 0.0031 0.0064 0.0316
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0013 0.0011 0.0013
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0013 0.001 0.0005
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0022 0.0036 0.0061
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.011 0.0106
Mycobacterium ulcerans lipase LipD 0.0024 0.0042 0.0255
Giardia lamblia GTOR 0.0238 0.0678 0.3855
Mycobacterium tuberculosis Class a beta-lactamase BlaC 0.0181 0.0508 0.0769
Loa Loa (eye worm) hypothetical protein 0.0031 0.0064 0.0364
Loa Loa (eye worm) phosphatidylinositol kinase 0.0048 0.0114 0.0673
Trichomonas vaginalis glutamate synthase, putative 0.0013 0.001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0049 0.0116 0.1598
Mycobacterium tuberculosis Conserved protein 0.0015 0.0017 0.0025
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0013 0.001 0.0004
Giardia lamblia Pyruvate kinase 0.0023 0.0039 0.0175
Entamoeba histolytica disulphide oxidoreductase, putative 0.0013 0.001 0.0004
Echinococcus multilocularis X box binding protein 1 0.019 0.0535 0.053
Trichomonas vaginalis phosphofructokinase, putative 0.015 0.0418 0.2357
Echinococcus multilocularis neuropeptide Y receptor 0.0047 0.011 0.0106
Trichomonas vaginalis D-aminoacylase, putative 0.0024 0.0042 0.0188
Echinococcus multilocularis microtubule associated protein 2 0.1727 0.5099 0.5097
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.011 0.0106
Brugia malayi serine/threonine-protein kinase plk-2 0.0193 0.0544 0.334
Brugia malayi Regulator of G protein signaling domain containing protein 0.0013 0.0011 0.0069
Loa Loa (eye worm) hypothetical protein 0.0013 0.0011 0.0041
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0146 0.0141
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0238 0.0678 0.0673
Leishmania major hypothetical protein, conserved 0.0024 0.0042 0.0091
Echinococcus granulosus neuropeptide receptor 0.0047 0.011 0.0106
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0013 0.0009 0.0004
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0022 0.0036 0.0031
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0047 0.011 0.0675
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0014 0.0061
Mycobacterium leprae conserved hypothetical protein 0.0024 0.0042 0.0189
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0047 0.011 0.0649
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0047 0.011 0.0207
Loa Loa (eye worm) DR-78 0.0019 0.0029 0.0149
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.0093 0.0573
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0049 0.0116 0.2874
Loa Loa (eye worm) TAR-binding protein 0.0045 0.0103 0.0609
Mycobacterium leprae PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) 0.0016 0.0019 0.0084
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0077 0.0201 0.1107
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0041 0.0093 0.0174
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0013 0.001 0.0004
Leishmania major hypothetical protein, conserved 0.0013 0.001 0.0002
Echinococcus granulosus 7tm_1 domain containing protein 0.0047 0.011 0.0106
Schistosoma mansoni serine/threonine protein kinase 0.0014 0.0013 0.0017
Toxoplasma gondii pyruvate kinase PyK1 0.0045 0.0104 0.1417
Mycobacterium ulcerans pyruvate kinase 0.0045 0.0104 0.0637
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0054 0.0131 0.0199
Mycobacterium tuberculosis Probable conserved lipoprotein LpqF 0.0087 0.0229 0.0347
Treponema pallidum replicative DNA helicase (dnaB) 0.0255 0.0727 0.4138
Loa Loa (eye worm) melatonin receptor type 1A 0.0047 0.011 0.0649
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0047 0.011 0.0207
Echinococcus multilocularis g protein coupled receptor 0.0047 0.011 0.0106
Trypanosoma brucei polo-like protein kinase 0.0193 0.0544 0.8001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0116 0.0308
Echinococcus multilocularis pyruvate kinase 0.0045 0.0104 0.0099
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0049 0.0116 0.0296
Echinococcus granulosus somatostatin receptor 0.0047 0.011 0.0106
Mycobacterium tuberculosis Probable hydrolase 0.0024 0.0042 0.0063
Brugia malayi Cytochrome P450 family protein 0.0015 0.0014 0.0089
Schistosoma mansoni nephrin 0.0014 0.0013 0.0017
Mycobacterium tuberculosis Probable replicative DNA helicase DnaB 0.2232 0.66 1
Echinococcus multilocularis GPCR, family 2 0.0021 0.0034 0.0029
Mycobacterium tuberculosis Polyketide synthetase MbtD (polyketide synthase) 0.0016 0.0018 0.0027
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.011 0.0207
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.001 0.0002
Giardia lamblia Glutamate synthase 0.0013 0.001 0.0004
Trichomonas vaginalis CAMK family protein kinase 0.0193 0.0544 0.3085
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0048 0.0114 0.0605
Schistosoma mansoni histamine h1 receptor 0.0047 0.011 0.0207
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.015 0.0418 0.1179
Trichomonas vaginalis PIKK family atypical protein kinase 0.0135 0.0373 0.2101
Trypanosoma cruzi trypanothione reductase, putative 0.0049 0.0116 0.0308
Brugia malayi regulator of G-protein signaling rgs-7 0.0013 0.0011 0.0069
Brugia malayi Pyruvate kinase, muscle isozyme 0.0045 0.0104 0.0637
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0077 0.0201 0.2871
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0085 0.0222 0.1366
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0031 0.0064 0.0363
Loa Loa (eye worm) hypothetical protein 0.0019 0.0029 0.0149
Plasmodium falciparum pyruvate kinase 2 0.0023 0.0039 0.0873
Loa Loa (eye worm) hypothetical protein 0.0086 0.0227 0.137
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0135 0.0373 0.0369
Mycobacterium ulcerans DNA polymerase IV 0.0013 0.0009 0.0055
Trichomonas vaginalis bromodomain-containing protein, putative 0.003 0.006 0.0296
Loa Loa (eye worm) hypothetical protein 0.0012 0.0006 0.0008
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0013 0.001 0.0098
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0068 0.0172 0.0941
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.011 0.0106
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0193 0.0544 0.3321
Leishmania major phosphopantetheinyl transferase-like protein 0.0048 0.0113 0.0288
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0041 0.0093 0.0573
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0041 0.0093 0.0573
Echinococcus multilocularis g protein coupled receptor 0.0047 0.011 0.0106
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0013 0.001 0.0007
Echinococcus multilocularis G protein coupled receptor 139 0.0047 0.011 0.0106
Schistosoma mansoni growth hormone secretagogue receptor 0.0047 0.011 0.0207
Loa Loa (eye worm) 6-phosphofructokinase 0.015 0.0418 0.2544
Echinococcus multilocularis transcription factor eb 0.015 0.0415 0.0411
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0047 0.011 0.0207
Echinococcus multilocularis pyruvate kinase 0.0023 0.0039 0.0035
Entamoeba histolytica phosphofructokinase, putative 0.015 0.0418 0.2357
Brugia malayi beta-lactamase family protein 0.0024 0.0042 0.0255
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0041 0.0093 0.0089
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.0013 0.0009 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0678 0.3855
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.0181 0.0508 0.3118
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Plasmodium falciparum pyruvate kinase 0.0045 0.0104 0.256
Entamoeba histolytica hypothetical protein 0.0048 0.0113 0.06
Echinococcus granulosus thyroid hormone receptor alpha 0.0019 0.0029 0.0024
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0013 0.001 0.0058
Schistosoma mansoni amine GPCR 0.0047 0.011 0.0207
Loa Loa (eye worm) RNA binding protein 0.0045 0.0103 0.0609
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0029 0.0024
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.011 0.0207
Leishmania major cytochrome p450-like protein 0.0015 0.0014 0.0016
Giardia lamblia Histone acetyltransferase GCN5 0.0027 0.0053 0.0253
Brugia malayi nuclear receptor RXR 0.0019 0.0029 0.0177
Toxoplasma gondii target of rapamycin (TOR), putative 0.0238 0.0678 1
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0049 0.0116 0.0296
Plasmodium vivax SET domain protein, putative 0.0061 0.0152 0.3824
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0135 0.0373 0.2292
Leishmania major trypanothione reductase 0.0141 0.0389 0.1052
Echinococcus multilocularis sex peptide receptor 0.0047 0.011 0.0106
Trichomonas vaginalis phosphofructokinase, putative 0.0041 0.0092 0.0478
Leishmania major calcium/potassium channel (CAKC), putative 0.0025 0.0045 0.0099
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.0093 0.0089
Entamoeba histolytica hypothetical protein 0.0013 0.0011 0.0013
Trypanosoma cruzi polo-like protein kinase, putative 0.0193 0.0544 0.1543
Brugia malayi Serotonin receptor 0.0047 0.011 0.0675
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0238 0.0678 0.0673
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0016 0.0018 0.008
Mycobacterium ulcerans ferredoxin reductase 0.0013 0.001 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0156
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0047 0.011 0.0106
Toxoplasma gondii type I fatty acid synthase, putative 0.0055 0.0133 0.186
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0597 0.1744 1
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0047 0.011 0.0207
Brugia malayi hypothetical protein 0.0047 0.011 0.0675
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0135 0.0373 0.2292
Loa Loa (eye worm) hypothetical protein 0.0041 0.0093 0.0547
Brugia malayi nuclear receptor NHR-88 0.0019 0.0029 0.0177
Echinococcus granulosus tumor protein p63 0.023 0.0654 0.065
Loa Loa (eye worm) pyruvate kinase 0.0045 0.0104 0.0611
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0013 0.001 0.001
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0051 0.0122 0.075
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0058 0.0143 0.3575
Plasmodium vivax flap endonuclease 1, putative 0.0018 0.0026 0.0516
Brugia malayi hypothetical protein 0.0047 0.011 0.0675
Echinococcus multilocularis pyruvate kinase 0.0023 0.0039 0.0035
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0049 0.0116 0.0296
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0255 0.1417
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0013 0.0009 0.0055
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0015 0.0015 0.0011
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0013 0.0009 0.0027
Toxoplasma gondii ion channel protein 0.0025 0.0045 0.0534
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0011 0.0004 0.0006
Schistosoma mansoni adenoreceptor 0.0047 0.011 0.0207
Onchocerca volvulus 0.0048 0.0114 0.0746
Echinococcus granulosus muscleblind protein 0.0305 0.0877 0.0873
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0678 0.3855
Echinococcus multilocularis regulator of G protein signaling 3 0.0013 0.0011 0.0007
Mycobacterium leprae PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase 0.0255 0.0727 0.3305
Echinococcus multilocularis dro:myosuppressin receptor 0.0047 0.011 0.0106
Schistosoma mansoni regulator of G protein signaling 0.0013 0.0011 0.0013
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0047 0.011 0.0207
Schistosoma mansoni neuropeptide receptor 0.0047 0.011 0.0207
Entamoeba histolytica hypothetical protein 0.0048 0.0114 0.0605
Onchocerca volvulus Pyruvate kinase homolog 0.0045 0.0104 0.0674
Loa Loa (eye worm) hypothetical protein 0.0012 0.0006 0.0008
Schistosoma mansoni kinase 0.0098 0.0262 0.0506
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0013 0.001 0.0004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0041 0.0093 0.0547
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0238 0.0678 0.1321
Leishmania major phosphatidylinositol 3-kinase, putative 0.0058 0.0143 0.037
Onchocerca volvulus Pyruvate kinase homolog 0.0045 0.0104 0.0674
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0048 0.0113 0.0693
Echinococcus granulosus biogenic amine 5HT receptor 0.0047 0.011 0.0106
Brugia malayi hypothetical protein 0.0019 0.0029 0.0177
Brugia malayi ecdysone receptor 0.0019 0.0029 0.0177
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0013 0.0011 0.0013
Plasmodium falciparum 3-oxoacyl-acyl-carrier protein synthase I/II 0.0013 0.0009 0.0085
Onchocerca volvulus 0.0093 0.0248 0.1702
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0022 0.0038 0.0084
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Giardia lamblia Thioredoxin reductase 0.0013 0.001 0.0004
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.004 0.009 0.0224
Plasmodium vivax potassium channel, putative 0.0025 0.0045 0.1017
Schistosoma mansoni neuropeptide receptor 0.0047 0.011 0.0207
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0093 0.0248 0.1379
Trichomonas vaginalis penicillin-binding protein, putative 0.0024 0.0042 0.0188
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0041 0.0092 0.0474
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0119
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0042 0.0489
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0013 0.001 0.0007
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0013 0.001 0.0058
Echinococcus multilocularis geminin 0.0346 0.0999 0.0995
Trypanosoma brucei beta-ketoacyl-ACP synthase 0.0013 0.0009 0.0002
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0255 0.1417
Onchocerca volvulus Bile acid receptor homolog 0.0041 0.0093 0.06
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0061 0.0152 0.0148
Echinococcus multilocularis tumor protein p63 0.023 0.0654 0.065
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0151 0.0418 0.612
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0013 0.0009 0.0009
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0042 0.0094
Leishmania major phosphatidylinositol 3-kinase, putative 0.0238 0.0678 0.1853
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0292 0.0837 0.5138
Onchocerca volvulus 0.0024 0.0042 0.0229
Echinococcus granulosus potassium large conductance calcium activated 0.0093 0.0248 0.0244
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0114 0.0605
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0192
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0041 0.0092 0.2247
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0151 0.0418 0.6121
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0048 0.0114 0.157
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0019 0.0029 0.0048
Echinococcus multilocularis neuropeptide FF receptor 2 0.0047 0.011 0.0106
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0013 0.001 0.0007
Mycobacterium ulcerans acyl-CoA synthetase 0.0016 0.0018 0.0107
Loa Loa (eye worm) hypothetical protein 0.0016 0.0018 0.008
Trichomonas vaginalis pyruvate kinase, putative 0.0045 0.0104 0.0547
Mycobacterium tuberculosis Probable esterase LipL 0.0024 0.0042 0.0063
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0049 0.0116 0.1598
Schistosoma mansoni tar DNA-binding protein 0.0045 0.0103 0.0194
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0047 0.011 0.0106
Echinococcus granulosus dna polymerase kappa 0.0013 0.0009 0.0004
Echinococcus granulosus pyruvate kinase 0.0023 0.0039 0.0035
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0047 0.011 0.0106
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] synthase i/ii, putative 0.0013 0.0009 0.0085
Schistosoma mansoni calcium-activated potassium channel 0.0093 0.0248 0.0478
Loa Loa (eye worm) hypothetical protein 0.0045 0.0104 0.0611
Schistosoma mansoni myosin xvIII 0.0047 0.011 0.0207
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0047 0.011 0.0106
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0048 0.0113 0.1447
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0022 0.0036 0.0156
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0047 0.011 0.0106
Echinococcus granulosus g protein coupled receptor 0.0047 0.011 0.0106
Onchocerca volvulus 0.0103 0.0276 0.1909
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0047 0.011 0.0207
Brugia malayi nuclear hormone receptor family member odr-7 0.0019 0.0029 0.0177
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0077 0.0201 0.0385
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.011 0.0106
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0058 0.0143 0.0771
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0678 0.3855
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0051 0.0122 0.0555
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0052 0.0126 0.0747
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0041 0.0092 0.0478
Plasmodium falciparum thioredoxin reductase 0.0049 0.0116 0.2874
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Schistosoma mansoni axis inhibition protein axin 0.0013 0.0011 0.0013
Brugia malayi G protein-coupled receptor F59B2.13 0.0047 0.011 0.0675
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0048 0.0114 0.0699
Echinococcus granulosus alpha 1A adrenergic receptor 0.0047 0.011 0.0106
Brugia malayi hypothetical protein 0.0011 0.0005 0.0028
Schistosoma mansoni serine/threonine protein kinase 0.0014 0.0013 0.0017
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0015 0.0016 0.0272
Trichomonas vaginalis conserved hypothetical protein 0.0151 0.0418 0.236
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0047 0.011 0.0106
Entamoeba histolytica Flap nuclease, putative 0.0018 0.0026 0.0096
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0047 0.011 0.0649
Echinococcus multilocularis glutamate synthase 0.0013 0.001 0.0005
Treponema pallidum recombinase A 0.0071 0.0182 0.0996
Echinococcus granulosus serotonin receptor 0.0047 0.011 0.0106
Mycobacterium ulcerans polyketide synthase MbtD 0.0016 0.0018 0.0108
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0193 0.0544 0.054
Mycobacterium ulcerans acyl-CoA synthetase 0.0016 0.0018 0.0107
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0238 0.0678 0.1321
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0678 0.3855
Schistosoma mansoni biogenic amine receptor 0.0047 0.011 0.0207
Entamoeba histolytica hypothetical protein 0.0122 0.0333 0.1866
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0678 0.3855
Mycobacterium ulcerans DNA polymerase IV 0.0013 0.0009 0.0055
Leishmania major 4-coumarate:coa ligase-like protein 0.0016 0.0018 0.0024
Trichomonas vaginalis phosphofructokinase, putative 0.015 0.0418 0.2357
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0047 0.011 0.0207
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.0093 0.0089
Schistosoma mansoni tar DNA-binding protein 0.0045 0.0103 0.0194
Schistosoma mansoni 6-phosphofructokinase 0.015 0.0418 0.0811
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0077 0.0201 0.1107
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0013 0.001 0.0014
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0048 0.0114 0.2824
Schistosoma mansoni aldehyde dehydrogenase 0.004 0.009 0.0168
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0013 0.001 0.0098
Mycobacterium leprae Polyketide synthase Pks13 0.0076 0.0197 0.0895
Onchocerca volvulus 0.0047 0.011 0.0719
Echinococcus granulosus neuropeptide s receptor 0.0784 0.2298 0.2295
Echinococcus multilocularis fmrfamide receptor 0.0047 0.011 0.0106
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0013 0.001 0.0058
Onchocerca volvulus 0.0018 0.0023 0.0099
Schistosoma mansoni nuclear receptor 0.0019 0.0029 0.0048
Entamoeba histolytica phosphofructokinase, putative 0.015 0.0418 0.2357
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0019 0.0029 0.0149
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0678 0.3855
Loa Loa (eye worm) phosphatidylinositol 3 0.0048 0.0114 0.0673
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.003 0.006 0.0296
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0238 0.0678 1
Brugia malayi Pyruvate kinase, M2 isozyme 0.0045 0.0104 0.0637
Mycobacterium ulcerans replicative DNA helicase DnaB 0.0255 0.0727 0.4463
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0077 0.0201 0.1107
Trypanosoma brucei trypanothione reductase 0.0141 0.0389 0.5677
Onchocerca volvulus 0.0484 0.1408 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0021 0.0034 0.0029
Loa Loa (eye worm) pyruvate kinase 0.0045 0.0104 0.0611
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0018 0.0027
Loa Loa (eye worm) hypothetical protein 0.0019 0.0029 0.0149
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0013 0.001 0.0002
Mycobacterium ulcerans polyketide synthase Pks9 0.0034 0.0071 0.0436
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.003 0.006 0.0765
Treponema pallidum NADH oxidase 0.0049 0.0116 0.0613
Chlamydia trachomatis thioredoxin reductase 0.0013 0.001 0.0052
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0597 0.1744 1
Schistosoma mansoni hypothetical protein 0.019 0.0535 0.1041
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.015 0.0418 0.2354
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0029 0.0177
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0047 0.011 0.0106
Echinococcus granulosus axis inhibition protein axin 0.0013 0.0011 0.0007
Schistosoma mansoni hypothetical protein 0.0047 0.011 0.0207
Chlamydia trachomatis replicative DNA helicase 0.0255 0.0727 1
Onchocerca volvulus 0.0047 0.011 0.0719
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0114 0.0605
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0022 0.0036 0.0075
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0011 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.011 0.0106
Loa Loa (eye worm) neuropeptide F receptor 0.0047 0.011 0.0649
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0031 0.0064 0.0116
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0048 0.0113 0.1554
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0041 0.0093 0.0573
Echinococcus granulosus aryl hydrocarbon receptor 0.0074 0.019 0.0186
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0041 0.0093 0.0089
Loa Loa (eye worm) hypothetical protein 0.0025 0.0045 0.0248
Trichomonas vaginalis PIKK family atypical protein kinase 0.0135 0.0373 0.2101
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0047 0.011 0.0106
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0048 0.0114 0.0109
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0238 0.0678 1
Echinococcus granulosus tm gpcr rhodopsin 0.0047 0.011 0.0106
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0107 0.029 0.0286
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0048 0.0114 0.0699
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.0093 0.0089
Onchocerca volvulus 0.017 0.0475 0.3332
Brugia malayi photoreceptor-specific nuclear receptor 0.0041 0.0093 0.0573
Toxoplasma gondii aldehyde dehydrogenase 0.004 0.009 0.121
Brugia malayi PXA domain containing protein 0.0013 0.0011 0.0069
Onchocerca volvulus 0.0047 0.011 0.0719
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0013 0.001 0.0014
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0054 0.0131 0.0807
Mycobacterium ulcerans glutamate synthase subunit beta 0.0013 0.001 0.0058
Loa Loa (eye worm) hypothetical protein 0.0087 0.0231 0.1391
Brugia malayi steroid hormone receptor 0.0041 0.0093 0.0573
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0018 0.0026 0.0249
Brugia malayi Nuclear hormone receptor-like 1 0.0041 0.0093 0.0573
Mycobacterium tuberculosis Hypothetical protein 0.0015 0.0017 0.0025
Loa Loa (eye worm) hypothetical protein 0.0019 0.0029 0.0149
Schistosoma mansoni tar DNA-binding protein 0.0045 0.0103 0.0194
Echinococcus granulosus twitchin 0.0015 0.0015 0.001
Treponema pallidum fructose-bisphosphate aldolase 0.0597 0.1744 1
Loa Loa (eye worm) hypothetical protein 0.0135 0.0373 0.227
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0041 0.0093 0.0174
Loa Loa (eye worm) nuclear hormone receptor 0.0019 0.0029 0.0149
Schistosoma mansoni 3-oxoacyl-[ACP] synthase 0.0013 0.0009 0.0009
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0041 0.0093 0.0089
Echinococcus granulosus pyruvate kinase 0.0023 0.0039 0.0035
Echinococcus granulosus 6 phosphofructokinase 0.015 0.0418 0.0413
Onchocerca volvulus 0.0016 0.0018 0.0057
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0048 0.0113 0.0171
Loa Loa (eye worm) hypothetical protein 0.0041 0.0093 0.0547
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0356 0.103 0.468
Mycobacterium leprae Probable polyketide synthase Pks1 0.0054 0.0131 0.0598
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0013 0.001 0.0058
Onchocerca volvulus 0.0047 0.011 0.0719
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0013 0.001 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0678 0.3855
Entamoeba histolytica protein kinase rad3, putative 0.0135 0.0373 0.2101
Loa Loa (eye worm) hypothetical protein 0.0019 0.0029 0.0149
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0016 0.0018 0.0107
Brugia malayi hypothetical protein 0.0022 0.0036 0.0219
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0226 0.0642 0.0638
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0135 0.0373 0.0724
Brugia malayi Tachykinin-like peptides receptor 99D 0.0047 0.011 0.0675
Echinococcus granulosus regulator of G protein signaling 7 0.0013 0.0011 0.0007
Schistosoma mansoni single-minded 0.0022 0.0036 0.0062
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0678 0.3855
Loa Loa (eye worm) hypothetical protein 0.0073 0.0187 0.1124
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Loa Loa (eye worm) hypothetical protein 0.0028 0.0056 0.0315
Loa Loa (eye worm) hypothetical protein 0.0048 0.0114 0.0673
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.011 0.0106
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0597 0.1744 1
Trichomonas vaginalis CAMK family protein kinase 0.0193 0.0544 0.3085
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0051 0.0122 0.075
Schistosoma mansoni serine/threonine protein kinase 0.0193 0.0544 0.1059
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0048 0.0114 0.2824
Schistosoma mansoni thyroid hormone receptor 0.0041 0.0093 0.0174
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0141 0.0391 0.1102
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0597 0.1744 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0031 0.0064 0.0059
Schistosoma mansoni hypothetical protein 0.0346 0.0999 0.1952
Echinococcus granulosus dna polymerase eta 0.0013 0.0009 0.0004
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0238 0.0678 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0678 0.3855
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0238 0.0678 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0678 0.3855
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0114 0.0605
Schistosoma mansoni amine GPCR 0.0047 0.011 0.0207
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0192
Onchocerca volvulus Fatty acid synthase homolog 0.0092 0.0243 0.1672
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0048 0.0114 0.0303
Leishmania major pyruvate kinase 0.0045 0.0104 0.0263
Echinococcus granulosus roundabout 2 0.0018 0.0024 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0087 0.0231 0.1278
Mycobacterium ulcerans lipoprotein LpqF 0.0087 0.0229 0.1404
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Trypanosoma cruzi NADH dehydrogenase, putative 0.0013 0.001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0024 0.0042 0.0228
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0102 0.0276 0.0271
Mycobacterium tuberculosis Probable reductase 0.0321 0.0923 0.1399
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0049 0.0116 0.1598
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0013 0.001 0.0004
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0048 0.0113 0.28
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0062 0.0155 0.0952
Entamoeba histolytica hypothetical protein 0.0013 0.0011 0.0013
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase 0.0255 0.0727 1
Trichomonas vaginalis phosphofructokinase, putative 0.0041 0.0092 0.0478
Schistosoma mansoni RAR-like nuclear receptor 0.0041 0.0093 0.0174
Brugia malayi regulator of G-protein signaling egl-10 0.0013 0.0011 0.0069
Brugia malayi ImpB/MucB/SamB family protein 0.0013 0.0009 0.0055
Echinococcus multilocularis neuropeptide Y receptor 0.0047 0.011 0.0106
Loa Loa (eye worm) hypothetical protein 0.0012 0.0006 0.0008
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0049 0.0116 0.0111
Brugia malayi Latrophilin receptor protein 2 0.0021 0.0034 0.0208
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0041 0.0093 0.06
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0141 0.0391 0.2202
Onchocerca volvulus 0.0073 0.0187 0.127
Echinococcus granulosus 7TM GPCR rhodopsin 0.0047 0.011 0.0106
Schistosoma mansoni hypothetical protein 0.0048 0.0114 0.0215
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0135 0.0373 0.1051
Onchocerca volvulus 0.0047 0.011 0.0719
Mycobacterium tuberculosis Probable lipase LipD 0.0024 0.0042 0.0063
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0029 0.0024
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0013 0.001 0.001
Brugia malayi hypothetical protein 0.0086 0.0227 0.1393
Brugia malayi aryl hydrocarbon receptor AHR-1 0.0051 0.0122 0.0751
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0047 0.011 0.0675
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0021 0.0034 0.0029
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0029 0.0138
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0048 0.0114 0.157
Trichomonas vaginalis PIKK family atypical protein kinase 0.0151 0.0418 0.236
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0051 0.0122 0.0555
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0077 0.0201 0.1107
Onchocerca volvulus Neuropeptide F receptor homolog 0.0047 0.011 0.0719
Echinococcus multilocularis neuropeptide receptor A26 0.0784 0.2298 0.2295
Entamoeba histolytica hypothetical protein 0.0048 0.0114 0.0605
Brugia malayi nuclear hormone receptor 0.0041 0.0093 0.0573
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0102 0.0274 0.0529
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0022 0.0036 0.0078
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0048 0.0114 0.2824
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0076 0.0197 0.0298
Brugia malayi hypothetical protein 0.0013 0.0011 0.0069
Brugia malayi hypothetical protein 0.0052 0.0125 0.0768
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0041 0.0093 0.0547
Loa Loa (eye worm) phosphatidylinositol 3 0.0048 0.0114 0.0673
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0019 0.0029 0.0177
Loa Loa (eye worm) thioredoxin reductase 0.0141 0.0389 0.2364
Onchocerca volvulus 0.0061 0.0152 0.102
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0058 0.0143 0.0771
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Schistosoma mansoni glutamate synthase 0.0013 0.001 0.001
Schistosoma mansoni amine GPCR 0.0047 0.011 0.0207
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Echinococcus granulosus fmrfamide receptor 0.0047 0.011 0.0106
Trichomonas vaginalis phosphofructokinase, putative 0.0041 0.0092 0.0478
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0013 0.001 0.0005
Mycobacterium ulcerans aldehyde dehydrogenase 0.004 0.009 0.0552
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0321 0.0923 0.4197
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0193 0.0544 0.1482
Echinococcus granulosus histone acetyltransferase KAT2B 0.003 0.006 0.0056
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0042 0.0097 0.0441
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0022 0.0036 0.0156
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0013 0.001 0.001
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0014 0.0013 0.0052
Mycobacterium ulcerans recombinase A 0.0071 0.0182 0.1119
Schistosoma mansoni pyruvate kinase 0.0045 0.0104 0.0195
Brugia malayi putative neuropeptide receptor NPR1 0.0047 0.011 0.0675
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0321 0.0923 0.1399
Schistosoma mansoni cellular tumor antigen P53 0.0034 0.0071 0.0131
Loa Loa (eye worm) hypothetical protein 0.0051 0.0122 0.0725
Mycobacterium ulcerans aldehyde dehydrogenase 0.004 0.009 0.0552
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0048 0.0114 0.0215
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0041 0.0093 0.0089
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0074 0.019 0.1142
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0042 0.0094
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0031 0.0064 0.0116
Loa Loa (eye worm) hypothetical protein 0.0024 0.0042 0.0228
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0013 0.001 0.0043
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.011 0.0106
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0048 0.0114 0.0109
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0678 0.3855
Loa Loa (eye worm) hypothetical protein 0.0061 0.0152 0.0909
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0048 0.0114 0.0303
Trichomonas vaginalis D-aminoacylase, putative 0.0024 0.0042 0.0188
Schistosoma mansoni biogenic amine (5HT) receptor 0.0047 0.011 0.0207
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0045 0.0104 0.0157
Brugia malayi hypothetical protein 0.0047 0.011 0.0675
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0116 0.0308
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0058 0.0143 0.0271
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0029 0.0058 0.0142
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Mycobacterium tuberculosis Probable oxidoreductase 0.0356 0.103 0.156
Mycobacterium tuberculosis Polyketide synthetase MbtC (polyketide synthase) 0.0017 0.0023 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0135 0.0373 0.2101
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0678 0.3855
Echinococcus granulosus orexin receptor type 2 0.0047 0.011 0.0106
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.011 0.0106
Schistosoma mansoni disulfide oxidoreductase 0.0013 0.001 0.001
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0058 0.0143 0.0138
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.004 0.009 0.0136
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0013 0.001 0.0002
Brugia malayi hypothetical protein 0.0047 0.011 0.0675
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0013 0.001 0.0004
Schistosoma mansoni thyroid hormone receptor 0.0041 0.0093 0.0174
Trichomonas vaginalis D-aminoacylase, putative 0.0024 0.0042 0.0188
Schistosoma mansoni neuropeptide receptor 0.0047 0.011 0.0207
Mycobacterium ulcerans thioesterase 0.0042 0.0097 0.0595
Schistosoma mansoni hypothetical protein 0.0102 0.0276 0.0532
Onchocerca volvulus 0.0047 0.011 0.0719
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.017 0.0475 0.0924
Brugia malayi beta-lactamase family protein 0.0024 0.0042 0.0255
Brugia malayi hypothetical protein 0.0047 0.011 0.0675
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0022 0.0038 0.0084
Schistosoma mansoni 6-phosphofructokinase 0.015 0.0418 0.0811
Loa Loa (eye worm) MaxiK calcium-activated potassium channel 0.0062 0.0155 0.0927
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0041 0.0092 0.2247
Plasmodium falciparum histone acetyltransferase GCN5 0.0027 0.0053 0.1227
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0141 0.0391 0.2202
Schistosoma mansoni pyruvate kinase 0.0045 0.0104 0.0195
Brugia malayi Regulator of G protein signaling domain containing protein 0.0013 0.0011 0.0069
Brugia malayi FAT domain containing protein 0.0102 0.0276 0.1691
Trichomonas vaginalis CAMK family protein kinase 0.0193 0.0544 0.3085
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0013 0.001 0.0007
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0048 0.0113 0.1486
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0041 0.0093 0.0089
Schistosoma mansoni hypothetical protein 0.0047 0.011 0.0207
Onchocerca volvulus Pyruvate kinase homolog 0.0045 0.0104 0.0674
Echinococcus granulosus allatostatin A receptor 0.0047 0.011 0.0106
Loa Loa (eye worm) hypothetical protein 0.0041 0.0093 0.0547
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0058 0.0143 0.0138
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0022 0.0036 0.0156
Onchocerca volvulus 0.0047 0.011 0.0719
Leishmania major 4-coumarate:coa ligase-like protein 0.0016 0.0018 0.0024
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0029 0.0177
Brugia malayi hypothetical protein 0.0047 0.011 0.0675
Onchocerca volvulus 0.0014 0.0013 0.0021
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0042 0.0935
Schistosoma mansoni pyruvate kinase 0.0023 0.0039 0.0068
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0116 0.0308
Brugia malayi phosphofructokinase 0.015 0.0418 0.2564
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0025 0.0045 0.0103
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0013 0.001 0.0007
Trypanosoma cruzi calcium/potassium channel (CAKC), putative 0.0025 0.0045 0.0103
Schistosoma mansoni sulfide quinone reductase 0.0013 0.001 0.001
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0048 0.0113 0.1554
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.011 0.0106
Brugia malayi Calcitonin receptor-like protein seb-1 0.0067 0.0169 0.104
Brugia malayi MH2 domain containing protein 0.0079 0.0205 0.1256
Schistosoma mansoni opsin-like receptor 0.0047 0.011 0.0207
Brugia malayi larval opioid receptor 0.0047 0.011 0.0675
Plasmodium vivax glutathione reductase, putative 0.0141 0.0389 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.011 0.0207
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0049 0.0116 0.0711
Loa Loa (eye worm) hypothetical protein 0.0019 0.0029 0.0149
Schistosoma mansoni terminal deoxycytidyl transferase 0.0013 0.0009 0.0009
Mycobacterium leprae Probable lipase LipE 0.0024 0.0042 0.0189
Loa Loa (eye worm) hypothetical protein 0.0041 0.0093 0.0547
Echinococcus granulosus dro:myosuppressin receptor 0.0047 0.011 0.0106
Schistosoma mansoni amine GPCR 0.0047 0.011 0.0207
Mycobacterium ulcerans Type I modular polyketide synthase 0.0051 0.0122 0.075
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0013 0.001 0.0007
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0049 0.0116 0.1598
Loa Loa (eye worm) phosphatidylinositol 3 0.0029 0.0058 0.033
Trichomonas vaginalis adenylate cyclase, putative 0.0022 0.0036 0.0156
Leishmania major hypothetical protein, conserved 0.1228 0.3619 1
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0041 0.0093 0.0089
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Schistosoma mansoni z-protein (S1r protein) 0.0013 0.0011 0.0013
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0238 0.0678 0.0673
Trichomonas vaginalis glutathione reductase, putative 0.0049 0.0116 0.0616
Echinococcus granulosus pyruvate kinase 0.0023 0.0039 0.0035
Schistosoma mansoni opsin-like receptor 0.0047 0.011 0.0207
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0047 0.011 0.0719
Loa Loa (eye worm) hypothetical protein 0.017 0.0475 0.2898
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0048 0.0114 0.1568
Leishmania major pyruvate kinase 0.0045 0.0104 0.0263
Schistosoma mansoni biogenic amine (5HT) receptor 0.0047 0.011 0.0207
Loa Loa (eye worm) flap endonuclease-1 0.0018 0.0026 0.0129
Giardia lamblia Pyruvate kinase 0.0045 0.0104 0.0547
Echinococcus granulosus tachykinin peptides receptor 99D 0.0047 0.011 0.0106
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0016 0.0018 0.0086
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0022 0.0036 0.0419
Echinococcus granulosus neuropeptide Y receptor 0.0047 0.011 0.0106
Mycobacterium ulcerans thioesterase TesA 0.0042 0.0097 0.0595
Schistosoma mansoni regulator of G protein signaling 0.0013 0.0011 0.0013
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0041 0.0093 0.0569
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0041 0.0093 0.0421
Echinococcus multilocularis ecdysone induced protein 78C 0.0041 0.0093 0.0089
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0048 0.0114 0.1568
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.011 0.0207
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0047 0.011 0.0207
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0678 0.3855
Loa Loa (eye worm) glutaminase 2 0.0558 0.1629 1
Entamoeba histolytica hypothetical protein 0.0013 0.0011 0.0013
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0018 0.0113
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.011 0.0106
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0052 0.0125 0.0768
Trichomonas vaginalis mercuric reductase, putative 0.0049 0.0116 0.0616
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0049 0.0116 0.0308
Brugia malayi glutamate synthase 0.0013 0.001 0.0058
Echinococcus granulosus geminin 0.0346 0.0999 0.0995
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0077 0.0201 0.1233
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0013 0.001 0.0007
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0047 0.011 0.0649
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0321 0.0923 0.1399
Onchocerca volvulus 0.0047 0.011 0.0719
Echinococcus multilocularis Regulator of G protein signaling 20 0.0013 0.0011 0.0007
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0292 0.0837 0.1268
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0023 0.0039 0.0034
Toxoplasma gondii ion channel protein 0.0025 0.0045 0.0534
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0238 0.0678 0.416
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.011 0.0207
Schistosoma mansoni steroid hormone receptor ad4bp 0.0041 0.0093 0.0174
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0041 0.0092 0.0478
Onchocerca volvulus 0.0024 0.0042 0.0229
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0152 0.029
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0013 0.001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0041 0.0093 0.0547
Schistosoma mansoni fkbp-rapamycin associated protein 0.0135 0.0373 0.0724
Echinococcus multilocularis neuropeptides capa receptor 0.0047 0.011 0.0106
Echinococcus multilocularis G-protein coupled receptor, putative 0.0047 0.011 0.0106
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0011 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0192
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0047 0.011 0.0106
Trichomonas vaginalis apoptosis inducing factor, putative 0.0013 0.001 0.0004
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0019 0.0029 0.0024
Loa Loa (eye worm) beta-ketoacyl synthase domain-containing protein 0.0013 0.0009 0.0028
Echinococcus granulosus pyruvate kinase 0.0045 0.0104 0.0099
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0238 0.0678 0.3855
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0013 0.001 0.0004
Schistosoma mansoni aryl hydrocarbon receptor nuclear translocator homolog (darnt) 0.0052 0.0125 0.0237
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0041 0.0093 0.0573
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0049 0.0117 0.0178
Echinococcus granulosus glutamate synthase 0.0013 0.001 0.0005
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0149 0.0412 0.2511
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0048 0.0114 0.0215
Brugia malayi Cytochrome P450 family protein 0.0015 0.0014 0.0089
Mycobacterium tuberculosis Conserved hypothetical protein 0.0048 0.0114 0.0173
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0152 0.029
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.0021 0.0032 0.0049
Mycobacterium leprae conserved hypothetical protein 0.0048 0.0114 0.0518
Loa Loa (eye worm) glutaminase 0.0558 0.1629 1
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0058 0.0143 0.085
Echinococcus granulosus neuropeptide receptor A26 0.0784 0.2298 0.2295
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0014 0.0011 0.0069
Leishmania major NADH dehydrogenase, putative 0.0013 0.001 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0011 0.0013
Brugia malayi AMP-binding enzyme family protein 0.0016 0.0019 0.0119
Loa Loa (eye worm) hypothetical protein 0.0013 0.0011 0.0041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0678 0.3855
Echinococcus granulosus neuropeptide FF receptor 2 0.0047 0.011 0.0106
Trichomonas vaginalis PIKK family atypical protein kinase 0.0135 0.0373 0.2101
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0678 0.3855
Giardia lamblia Flap structure-specific endonuclease 0.0018 0.0026 0.0096
Giardia lamblia NADH oxidase lateral transfer candidate 0.0049 0.0116 0.0616
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0238 0.0678 0.1929
Brugia malayi hypothetical protein 0.0103 0.0276 0.1697
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0041 0.0093 0.0174
Leishmania major hypothetical protein, conserved 0.0013 0.001 0.0002
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0019 0.0029 0.0048
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Leishmania major hypothetical protein, conserved 0.0013 0.001 0.0002
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0096 0.0257 0.1579
Onchocerca volvulus 0.0047 0.011 0.0719
Trypanosoma cruzi NADH dehydrogenase, putative 0.0013 0.001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0024 0.0042 0.0228
Trichomonas vaginalis pyruvate kinase, putative 0.0045 0.0104 0.0547
Echinococcus multilocularis beta adrenergic receptor kinase 0.0014 0.0013 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0678 0.3855
Onchocerca volvulus Protein cycle homolog 0.0052 0.0125 0.0827
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0047 0.011 0.0649
Loa Loa (eye worm) nuclear receptor NHR-67 0.0019 0.0029 0.0149
Trichomonas vaginalis penicillin-binding protein, putative 0.0024 0.0042 0.0188
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0192
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0013 0.001 0.0005
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.0093 0.0089
Mycobacterium leprae conserved hypothetical protein 0.0048 0.0113 0.0513
Echinococcus granulosus neuropeptides capa receptor 0.0047 0.011 0.0106
Onchocerca volvulus 0.0047 0.011 0.0719
Mycobacterium ulcerans beta-lactamase 0.0024 0.0042 0.0255
Trichomonas vaginalis PIKK family atypical protein kinase 0.0135 0.0373 0.2101
Loa Loa (eye worm) hypothetical protein 0.0016 0.0018 0.008
Echinococcus multilocularis pyruvate kinase 0.0035 0.0076 0.0071
Brugia malayi hypothetical protein 0.0013 0.0011 0.0069
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0238 0.0678 0.0673
Plasmodium falciparum thioredoxin reductase 0.0141 0.0389 1
Schistosoma mansoni vesicular amine transporter 0.0018 0.0024 0.0038
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Schistosoma mansoni zinc finger protein 0.0019 0.0029 0.0048
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0048 0.0114 0.0215
Loa Loa (eye worm) hypothetical protein 0.0086 0.0227 0.137
Loa Loa (eye worm) steroid hormone receptor 0.0041 0.0093 0.0547
Echinococcus granulosus neuropeptide Y receptor 0.0047 0.011 0.0106
Brugia malayi conserved hypotetical protein 0.0019 0.0029 0.0177
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0678 0.3855
Onchocerca volvulus 0.0041 0.0093 0.06
Entamoeba histolytica acyl-coA synthetase, putative 0.0016 0.0018 0.005
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0047 0.011 0.0106
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0052 0.0125 0.0743
Brugia malayi nuclear receptor NHR-88 0.0041 0.0093 0.0573
Brugia malayi glutathione reductase 0.0141 0.0389 0.2385
Schistosoma mansoni regulator of G protein signaling 0.0013 0.0011 0.0013
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0321 0.0923 0.1399
Brugia malayi AMP-binding enzyme family protein 0.0016 0.0018 0.0107
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0678 0.3855
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0041 0.0092 0.1238
Brugia malayi AMP-binding enzyme family protein 0.0016 0.0018 0.0107
Echinococcus multilocularis g-protein coupled receptor 0.0047 0.011 0.0106
Brugia malayi Dopamine receptor protein 2 0.0047 0.011 0.0675
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.003 0.006 0.0765
Mycobacterium ulcerans polyketide synthase 0.0051 0.0122 0.075
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.011 0.0106
Echinococcus granulosus tm gpcr rhodopsin 0.0047 0.011 0.0106
Echinococcus multilocularis muscleblind protein 1 0.0305 0.0877 0.0873
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0041 0.0093 0.0569
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Echinococcus granulosus histone lysine methyltransferase setb 0.0061 0.0152 0.0148
Loa Loa (eye worm) hypothetical protein 0.0051 0.0122 0.0725
Schistosoma mansoni opsin-like receptor 0.0047 0.011 0.0207
Trypanosoma brucei cytochrome P450, putative 0.0015 0.0014 0.0084
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0047 0.011 0.0106
Echinococcus granulosus GPCR family 2 0.0021 0.0034 0.0029
Echinococcus multilocularis calcium activated potassium channel variant 0.0087 0.0229 0.0224
Brugia malayi Thioredoxin reductase 0.0141 0.0389 0.2385
Toxoplasma gondii ABC1 family protein 0.0024 0.0042 0.0487
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0678 0.3855
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0067 0.0169 0.104
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0192
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0036 0.0077 0.0475
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0041 0.0093 0.0573
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0047 0.011 0.0675
Loa Loa (eye worm) CYP4Cod1 0.0015 0.0014 0.0061
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0049 0.0116 0.2874
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0356 0.103 0.156
Plasmodium falciparum potassium channel 0.0025 0.0045 0.1017
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0051 0.0122 0.0185
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.0093 0.0573
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0058 0.0143 0.3575
Brugia malayi TAR-binding protein 0.0045 0.0103 0.0635
Echinococcus granulosus g-protein coupled receptor 0.0047 0.011 0.0106
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0049 0.0116 0.0711
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0048 0.0113 0.0596
Echinococcus granulosus beta-adrenergic receptor kinase 0.0014 0.0013 0.0009
Echinococcus granulosus calcium activated potassium channel variant 0.0087 0.0229 0.0224
Echinococcus granulosus sex peptide receptor 0.0047 0.011 0.0106
Echinococcus multilocularis calcium activated potassium channel 0.0094 0.025 0.0245
Onchocerca volvulus Serine\/threonine kinase homolog 0.0193 0.0544 0.3823
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0051 0.0122 0.0185
Loa Loa (eye worm) hypothetical protein 0.0019 0.0029 0.0149
Echinococcus multilocularis expressed protein 0.0262 0.0751 0.0747
Schistosoma mansoni tar DNA-binding protein 0.0045 0.0103 0.0194
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0029 0.0138
Loa Loa (eye worm) hypothetical protein 0.0024 0.0042 0.0228
Loa Loa (eye worm) hypothetical protein 0.0019 0.0029 0.0149
Brugia malayi Methyltransferase-like protein 4 0.0015 0.0017 0.0102
Trypanosoma cruzi DNA repair protein, putative 0.0022 0.0036 0.0079
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.015 0.0418 0.0633
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. 0.0071 0.0182 0.0828
Leishmania major hypothetical protein, unknown function 0.0048 0.0114 0.0291
Leishmania major protein kinase, putative 0.0022 0.0038 0.008
Brugia malayi AMP-binding enzyme family protein 0.0016 0.0018 0.0107
Mycobacterium ulcerans dehydrogenase 0.0013 0.001 0.0058
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0013 0.001 0.0004
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0049 0.0116 0.2874
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0067 0.0169 0.1015
Schistosoma mansoni glutamate synthase 0.0013 0.001 0.001
Brugia malayi ecdysteroid receptor 0.0041 0.0093 0.0573
Brugia malayi hypothetical protein 0.0047 0.011 0.0675
Schistosoma mansoni hypothetical protein 0.0047 0.011 0.0207
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0013 0.001 0.0031
Schistosoma mansoni calcium-activated potassium channel 0.0087 0.0229 0.044
Mycobacterium tuberculosis Conserved protein 0.0024 0.0042 0.0063
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0049 0.0116 0.0308
Toxoplasma gondii thioredoxin reductase 0.0141 0.0389 0.5676
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0678 0.3855
Leishmania major phosphatidylinositol kinase, putative 0.0048 0.0114 0.0291
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0014 0.0061
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0013 0.001 0.0005
Echinococcus granulosus tar DNA binding protein 0.0045 0.0103 0.0099
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0052 0.0126 0.0191
Brugia malayi beta-lactamase 0.0024 0.0042 0.0255
Trypanosoma cruzi pyruvate kinase 2, putative 0.0045 0.0104 0.0274
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0088 0.0232 0.1286
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0678 0.3855
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0041 0.0093 0.0174
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0013 0.001 0.0002
Plasmodium vivax 6-phosphofructokinase, putative 0.0041 0.0092 0.2247
Mycobacterium leprae Possible regulatory protein 0.0022 0.0036 0.0164
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0013 0.001 0.0004
Echinococcus multilocularis allatostatin A receptor 0.0047 0.011 0.0106
Trypanosoma cruzi target of rapamycin kinase 3 0.0238 0.0678 0.1929
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0041 0.0093 0.0547
Mycobacterium ulcerans hypothetical protein 0.0024 0.0042 0.0255
Schistosoma mansoni Replicative DNA helicase 0.0255 0.0727 0.1418
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0016 0.0018 0.0027
Plasmodium falciparum glutathione reductase 0.0049 0.0116 0.2874
Echinococcus multilocularis axis inhibition protein axin 0.0013 0.0011 0.0007
Loa Loa (eye worm) large conductance calcium-activated potassium channel alpha subunit ai 0.0087 0.0229 0.138
Plasmodium vivax 6-phosphofructokinase, putative 0.0041 0.0092 0.2247
Brugia malayi 6-phosphofructokinase 0.015 0.0418 0.2564
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0061 0.0152 0.0148
Loa Loa (eye worm) phosphatidylinositol 3 0.0238 0.0678 0.4144
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1104 0.3251 0.3248
Schistosoma mansoni hypothetical protein 0.0021 0.0034 0.0058
Brugia malayi hypothetical protein 0.0073 0.0187 0.1149
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0116 0.0308
Mycobacterium leprae Probable pyruvate kinase PykA 0.0045 0.0104 0.0472
Schistosoma mansoni neuropeptide F-like receptor 0.0047 0.011 0.0207
Giardia lamblia Fructose-bisphosphate aldolase 0.0597 0.1744 1
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0047 0.011 0.0106
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0013 0.001 0.0043
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0058 0.0143 0.0386
Brugia malayi hypothetical protein 0.0051 0.0122 0.0751
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0076 0.0197 0.0298
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.015 0.0418 0.6113
Mycobacterium leprae Conserved hypothetical protein 0.075 0.22 1
Loa Loa (eye worm) phosphatidylinositol 3 0.0048 0.0114 0.0673
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0029 0.0024
Toxoplasma gondii type I fatty acid synthase, putative 0.0036 0.0079 0.1041
Loa Loa (eye worm) hypothetical protein 0.0012 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Mycobacterium ulcerans polyketide synthase Pks13 0.0076 0.0197 0.1208
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0018 0.0026 0.0046
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.0013 0.0009 0.0055
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0152 0.0421 0.0638
Plasmodium vivax pyruvate kinase 2, putative 0.0023 0.0039 0.0873
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0048 0.0114 0.0109
Schistosoma mansoni hypothetical protein 0.0021 0.0034 0.0058
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0022 0.0036 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.0093 0.0573
Trichomonas vaginalis esterase, putative 0.0024 0.0042 0.0188
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0116 0.0308
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0011 0.0013
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0048 0.0114 0.0303
Brugia malayi 6-phosphofructokinase 0.015 0.0418 0.2564
Brugia malayi Cytochrome P450 family protein 0.0024 0.0043 0.0262
Loa Loa (eye worm) hypothetical protein 0.0041 0.0093 0.0547
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0058 0.0143 0.037
Brugia malayi nuclear hormone receptor family member nhr-6 0.0019 0.0029 0.0177
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0226 0.0642 0.1252
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0049 0.0116 0.0711
Echinococcus granulosus g protein coupled receptor 0.0047 0.011 0.0106
Plasmodium vivax thioredoxin reductase, putative 0.0141 0.0389 1
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0047 0.011 0.0207
Echinococcus granulosus nuclear receptor nhr 48 0.0019 0.0029 0.0024
Loa Loa (eye worm) hypothetical protein 0.0305 0.0877 0.5371
Trypanosoma brucei hypothetical protein, conserved 0.0013 0.001 0.001
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0011 0.0004 0.0006
Schistosoma mansoni regulator of G protein signaling 0.0013 0.0011 0.0013
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0013 0.0009 0.0013
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0047 0.011 0.0106
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Brugia malayi Muscleblind-like protein 0.0305 0.0877 0.5384
Mycobacterium tuberculosis Probable lipase LipE 0.0024 0.0042 0.0063
Trichomonas vaginalis CAMK family protein kinase 0.0193 0.0544 0.3085
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0048 0.0114 0.0109
Echinococcus granulosus biogenic amine 5HT receptor 0.0047 0.011 0.0106
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0597 0.1744 1
Giardia lamblia Kinase, PLK 0.0193 0.0544 0.3085
Brugia malayi nuclear receptor NHR-67 0.0019 0.0029 0.0177
Loa Loa (eye worm) G-protein coupled receptor 0.0047 0.011 0.0649
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0194
Toxoplasma gondii FATC domain-containing protein 0.0135 0.0373 0.5448
Echinococcus multilocularis thyroid hormone receptor alpha 0.0041 0.0093 0.0089
Echinococcus multilocularis thioredoxin glutathione reductase 0.0142 0.0392 0.0387
Brugia malayi Dopamine receptor 0.0047 0.011 0.0675
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0013 0.0011 0.0007
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0238 0.0678 0.1929
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0597 0.1744 1
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0013 0.001 0.0058
Trichomonas vaginalis CAMK family protein kinase 0.0193 0.0544 0.3085
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0024 0.0042 0.0073
Loa Loa (eye worm) hypothetical protein 0.0013 0.0011 0.0041
Brugia malayi hypothetical protein 0.0047 0.011 0.0675
Mycobacterium ulcerans 6-phosphofructokinase 0.015 0.0418 0.2564
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.0043 0.0235
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0111 0.0301 0.1686
Brugia malayi Fibronectin type III domain containing protein 0.0011 0.0005 0.0028
Mycobacterium tuberculosis Conserved protein 0.0024 0.0042 0.0063
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0321 0.0923 0.1399
Schistosoma mansoni tar DNA-binding protein 0.0045 0.0103 0.0194
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0049 0.0116 0.1487
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0013 0.001 0.0014
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0013 0.001 0.0043
Echinococcus multilocularis 6 phosphofructokinase 0.015 0.0418 0.0413
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0238 0.0678 0.1929
Echinococcus multilocularis neuropeptide receptor 0.0047 0.011 0.0106
Entamoeba histolytica serine/threonine protein kinase, putative 0.0193 0.0544 0.3085
Onchocerca volvulus 0.0047 0.011 0.0719
Echinococcus granulosus ecdysone induced protein 78C 0.0041 0.0093 0.0089
Brugia malayi Dopamine receptor protein 1 0.0047 0.011 0.0675
Echinococcus granulosus L aminoadipate semialdehyde 0.017 0.0475 0.0471
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0012 0.0006 0.0036
Brugia malayi Pre-SET motif family protein 0.0425 0.1233 0.7571
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0048 0.0114 0.0303
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0041 0.0092 0.1192
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0054 0.0131 0.0598
Echinococcus granulosus neuroglian 0.0014 0.0013 0.0009
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0058 0.0143 0.2
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0045 0.0103 0.0609
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.2049 0.6055 0.9175
Schistosoma mansoni biogenic amine receptor 0.0047 0.011 0.0207
Loa Loa (eye worm) hypothetical protein 0.0015 0.0015 0.0067
Loa Loa (eye worm) hypothetical protein 0.0013 0.001 0.0031
Onchocerca volvulus Protein ultraspiracle homolog 0.0041 0.0093 0.06
Echinococcus multilocularis regulator of G protein signaling 0.0013 0.0011 0.0007
Trypanosoma brucei recA bacterial DNA recombination protein, putative 0.0022 0.0036 0.0407
Echinococcus multilocularis muscleblind protein 0.0305 0.0877 0.0873
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0029 0.0024
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0111 0.0301 0.1686
Brugia malayi RE15519p 0.0047 0.011 0.0675
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0022 0.0038 0.0084
Loa Loa (eye worm) hypothetical protein 0.0034 0.0072 0.0414
Echinococcus multilocularis tar DNA binding protein 0.0045 0.0103 0.0099
Toxoplasma gondii 6-phosphofructokinase 0.0041 0.0092 0.1238
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0022 0.0038 0.0084
Schistosoma mansoni neuropeptide F-like receptor 0.0047 0.011 0.0207
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.011 0.0207
Loa Loa (eye worm) hypothetical protein 0.0067 0.0169 0.1015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0678 0.3855
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0024 0.0042 0.0063
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0049 0.0116 0.2874
Brugia malayi AKH receptor 0.0047 0.011 0.0675
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0027
Schistosoma mansoni regulator of G protein signaling 0.0013 0.0011 0.0013
Loa Loa (eye worm) hypothetical protein 0.0019 0.0029 0.0149
Loa Loa (eye worm) acyl carrier protein 0.0023 0.0041 0.0222
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0036 0.0219
Brugia malayi neuropeptide F receptor 0.0047 0.011 0.0675
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0061 0.0152 0.029
Echinococcus multilocularis serotonin receptor 0.0047 0.011 0.0106
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0021 0.0034 0.0208
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0024 0.0042 0.0255
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0135 0.0373 0.1051
Plasmodium vivax hypothetical protein, conserved 0.0015 0.0016 0.0272
Brugia malayi orphan nuclear receptor NR2E1 0.0019 0.0029 0.0177
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0238 0.0678 0.1853
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0597 0.1744 1
Echinococcus multilocularis neuropeptide receptor 0.0047 0.011 0.0106
Echinococcus multilocularis dna polymerase eta 0.0013 0.0009 0.0004
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0049 0.0116 0.1487
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0022 0.0036 0.0078
Loa Loa (eye worm) programmed cell death 8 0.0013 0.001 0.0031
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0013 0.001 0.0014
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0031 0.0064 0.0059
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0024 0.0042 0.0063
Schistosoma mansoni hypothetical protein 0.0047 0.011 0.0207
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0049 0.0116 0.1525
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0024 0.0042 0.0255
Echinococcus granulosus peptide allatostatin:somatostatin 0.0047 0.011 0.0106
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0018 0.0026 0.0048
Entamoeba histolytica acyl-CoA synthetase, putative 0.0021 0.0033 0.0138
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0011 0.0013
Brugia malayi hypothetical protein 0.0047 0.011 0.0675
Onchocerca volvulus 0.0047 0.011 0.0719
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0087 0.0231 0.0639
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0238 0.0678 0.3855
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0026 0.0049 0.0603
Brugia malayi ORL1-like opioid receptor 0.0047 0.011 0.0675
Echinococcus granulosus regulator of G protein signaling 3 0.0013 0.0011 0.0007
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0013 0.001 0.0004
Trichomonas vaginalis set domain proteins, putative 0.0484 0.1408 0.8063
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0141 0.0391 0.2202
Loa Loa (eye worm) hypothetical protein 0.0024 0.0042 0.0228
Leishmania major hypothetical protein, conserved 0.0015 0.0017 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.0093 0.0573
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0021 0.0034 0.0029
Onchocerca volvulus 0.0019 0.0029 0.0138
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0013 0.001 0.0058
Leishmania major phosphatidylinositol 4-kinase, putative 0.0048 0.0114 0.0291
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.011 0.0207
Echinococcus multilocularis L aminoadipate semialdehyde 0.017 0.0475 0.0471
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0048 0.0114 0.0699
Entamoeba histolytica hypothetical protein 0.0048 0.0114 0.0605
Mycobacterium ulcerans monoxygenase 0.0013 0.001 0.0058
Trichomonas vaginalis CAMK family protein kinase 0.0193 0.0544 0.3085
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0019 0.0029 0.0024
Mycobacterium ulcerans polyketide synthase 0.0054 0.0131 0.0807
Brugia malayi putative neuropeptide receptor 0.0047 0.011 0.0675
Trichomonas vaginalis phosphofructokinase, putative 0.0041 0.0092 0.0478
Mycobacterium ulcerans glutaminase 0.0558 0.1629 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.011 0.0106
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0102 0.0274 0.0269
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0141 0.0389 0.0589
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0017 0.0045
Trichomonas vaginalis guanylate cyclase, putative 0.0022 0.0036 0.0156
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0051 0.0122 0.0185
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0135 0.0373 0.2101
Trypanosoma brucei pyruvate kinase 1, putative 0.0045 0.0104 0.1419
Loa Loa (eye worm) hypothetical protein 0.0051 0.0122 0.0725
Loa Loa (eye worm) hypothetical protein 0.0012 0.0006 0.0008
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0013 0.001 0.0002
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0036 0.0219
Echinococcus granulosus 3 oxoacyl acyl carrier protein synthase 0.0013 0.0009 0.0005
Echinococcus multilocularis pyruvate kinase 0.0023 0.0039 0.0035
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0141 0.0391 0.2399
Echinococcus granulosus thioredoxin glutathione reductase 0.0142 0.0392 0.0387
Trichomonas vaginalis conserved hypothetical protein 0.0102 0.0276 0.1537
Loa Loa (eye worm) hypothetical protein 0.0103 0.0276 0.1674
Echinococcus granulosus Regulator of G protein signaling 20 0.0013 0.0011 0.0007
Mycobacterium ulcerans Type I modular polyketide synthase 0.0051 0.0122 0.075
Echinococcus granulosus expressed protein 0.0262 0.0751 0.0747
Brugia malayi hypothetical protein 0.0047 0.011 0.0675
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0052 0.0125 0.0768
Echinococcus multilocularis aryl hydrocarbon receptor 0.0074 0.019 0.0186
Echinococcus multilocularis 0.0048 0.0114 0.0109
Echinococcus multilocularis beta LACTamase domain containing family member 0.0024 0.0042 0.0037
Echinococcus granulosus calcium activated potassium channel 0.0094 0.025 0.0245
Trichomonas vaginalis PIKK family atypical protein kinase 0.0135 0.0373 0.2101
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0047 0.011 0.0649
Loa Loa (eye worm) phosphatidylinositol 3 0.0238 0.0678 0.4144
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0141 0.0391 0.2202
Onchocerca volvulus Huntingtin homolog 0.0086 0.0227 0.1555
Loa Loa (eye worm) hypothetical protein 0.0019 0.0029 0.0149
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.015 0.0418 0.1899
Schistosoma mansoni aldehyde dehydrogenase 0.004 0.009 0.0168
Loa Loa (eye worm) hypothetical protein 0.0305 0.0877 0.5371
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0238 0.0678 0.1929
Schistosoma mansoni sulfide quinone reductase 0.0013 0.001 0.001
Loa Loa (eye worm) pyruvate kinase 0.0045 0.0104 0.0611
Chlamydia trachomatis pyruvate kinase 0.0045 0.0104 0.1359
Onchocerca volvulus 0.0034 0.0071 0.044
Echinococcus multilocularis Zinc finger, PHD finger 0.0058 0.0143 0.0138
Schistosoma mansoni microtubule-associated protein tau 0.1727 0.5099 1
Schistosoma mansoni alpha-1 adrenergic receptor 0.0047 0.011 0.0207
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0238 0.0678 0.1853
Schistosoma mansoni amine GPCR 0.0047 0.011 0.0207
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0061 0.0152 0.2141
Echinococcus granulosus pyruvate kinase 0.0045 0.0104 0.0099
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0031 0.0064 0.039
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0077 0.0201 0.1107
Trypanosoma cruzi trypanothione reductase, putative 0.0141 0.0389 0.1095
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0238 0.0678 0.416
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0678 0.3855
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0107 0.029 0.0286
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0116 0.0308
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0011 0.0013
Mycobacterium ulcerans short-chain dehydrogenase 0.0011 0.0004 0.0024
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0013 0.001 0.0004
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0152 0.029
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0054 0.0131 0.0199
Brugia malayi RNA binding protein 0.0045 0.0103 0.0635
Loa Loa (eye worm) hypothetical protein 0.0019 0.0029 0.0149
Loa Loa (eye worm) beta-lactamase 0.0024 0.0042 0.0228
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0678 0.3855
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.004 0.009 0.0085
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0048 0.0114 0.0109
Echinococcus multilocularis g protein coupled receptor 0.0047 0.011 0.0106
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.015 0.0415 0.255
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0356 0.103 0.156
Brugia malayi sulfakinin receptor protein 0.0047 0.011 0.0675
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Loa Loa (eye worm) hypothetical protein 0.0151 0.0418 0.2547
Brugia malayi Immunoglobulin I-set domain containing protein 0.0011 0.0005 0.0028
Mycobacterium ulcerans hypothetical protein 0.0016 0.0018 0.0107
Loa Loa (eye worm) hypothetical protein 0.0024 0.0042 0.0228
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.0093 0.0573
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.017 0.0475 0.2918
Giardia lamblia Hypothetical protein 0.0048 0.0114 0.0605
Echinococcus granulosus neuropeptides capa receptor 0.0047 0.011 0.0106
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0058 0.0143 0.1998
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0135 0.0373 0.0369
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Toxoplasma gondii selenide, water dikinase 0.0013 0.001 0.0007
Onchocerca volvulus 0.0048 0.0114 0.0746
Loa Loa (eye worm) hypothetical protein 0.0041 0.0093 0.0547
Loa Loa (eye worm) hypothetical protein 0.0021 0.0034 0.0181
Echinococcus multilocularis axis inhibition protein axin 0.0013 0.0011 0.0007
Trichomonas vaginalis guanylate cyclase, putative 0.0022 0.0036 0.0156
Brugia malayi ImpB/MucB/SamB family protein 0.0013 0.0009 0.0055
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0193 0.0544 0.054
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0054 0.0131 0.0199
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0016 0.0018 0.0107
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0034 0.0071 0.0436
Schistosoma mansoni hypothetical protein 0.0046 0.0107 0.02
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0678 0.3855
Brugia malayi glutaminase DH11.1 0.0558 0.1629 1
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0013 0.0011 0.0013
Mycobacterium ulcerans NADH dehydrogenase 0.0013 0.001 0.0058
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0036 0.0077 0.0475
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0031 0.0064 0.0059
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0041 0.0092 0.0478
Schistosoma mansoni hypothetical protein 0.0021 0.0034 0.0058
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.011 0.0106
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0016 0.0018 0.0107
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0013 0.001 0.0098
Schistosoma mansoni methyltransferase-related 0.0015 0.0017 0.0024
Schistosoma mansoni cell adhesion molecule 0.0015 0.0015 0.0021
Loa Loa (eye worm) hypothetical protein 0.0107 0.029 0.1759
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0013 0.001 0.0005
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0135 0.0373 0.5449
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0013 0.001 0.0098
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0058 0.0143 0.0771
Onchocerca volvulus Huntingtin homolog 0.0086 0.0227 0.1555
Schistosoma mansoni hypothetical protein 0.0021 0.0034 0.0058
Echinococcus multilocularis fmrfamide receptor 0.0047 0.011 0.0106
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0238 0.0678 0.1853
Mycobacterium ulcerans aldehyde dehydrogenase 0.004 0.009 0.0552
Chlamydia trachomatis recombinase RecA 0.0071 0.0182 0.2446
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Mycobacterium tuberculosis Conserved hypothetical protein 0.0013 0.0009 0.0013
Brugia malayi AMP-binding enzyme family protein 0.0052 0.0126 0.0772
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0048 0.0114 0.0303
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0013 0.0011 0.0007
Onchocerca volvulus 0.0047 0.011 0.0719
Loa Loa (eye worm) phosphatidylinositol 3 0.0206 0.0584 0.3567
Trypanosoma brucei NADH dehydrogenase 0.0013 0.001 0.001
Schistosoma mansoni retinoic acid receptor RXR 0.0041 0.0093 0.0174
Loa Loa (eye worm) TYRA-2 protein 0.0047 0.011 0.0649
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0049 0.0116 0.0218
Trichomonas vaginalis flap endonuclease-1, putative 0.0018 0.0026 0.0096
Onchocerca volvulus 0.0019 0.0029 0.0138
Entamoeba histolytica acetyltransferase, GNAT family 0.0027 0.0053 0.0253
Loa Loa (eye worm) hypothetical protein 0.0046 0.0107 0.0629
Loa Loa (eye worm) hypothetical protein 0.0013 0.0011 0.0041
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0029 0.0048
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0047 0.011 0.0207
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0054 0.0131 0.0598
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0029 0.0048
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0031 0.0064 0.0059
Plasmodium falciparum flap endonuclease 1 0.0018 0.0026 0.0516
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0013 0.001 0.0005
Echinococcus multilocularis neuropeptide s receptor 0.0784 0.2298 0.2295
Trichomonas vaginalis phosphofructokinase, putative 0.0041 0.0092 0.0478
Schistosoma mansoni neuropeptide receptor 0.0047 0.011 0.0207
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0018 0.0026 0.0247
Trypanosoma cruzi polo-like protein kinase, putative 0.0193 0.0544 0.1543
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0016 0.0018 0.008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0678 0.3855
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0014 0.0013 0.008
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0047 0.011 0.0106
Brugia malayi G protein-coupled receptor 0.0047 0.011 0.0675
Echinococcus granulosus neuropeptide receptor 0.0047 0.011 0.0106
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0058 0.0143 0.0386
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0047 0.011 0.0106
Loa Loa (eye worm) hypothetical protein 0.0149 0.0412 0.2511
Loa Loa (eye worm) latrophilin receptor protein 2 0.0021 0.0034 0.0181
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0041 0.0093 0.0089
Loa Loa (eye worm) hypothetical protein 0.0051 0.0122 0.0725
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0011 0.0013
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0058 0.0143 0.0138
Brugia malayi Pre-SET motif family protein 0.0061 0.0152 0.0934
Mycobacterium ulcerans hypothetical protein 0.0013 0.001 0.0058
Brugia malayi RNA recognition motif domain containing protein 0.0045 0.0103 0.0635
Trypanosoma cruzi hypothetical protein, conserved 0.118 0.3476 1
Trypanosoma brucei beta lactamase 0.0087 0.0229 0.3288
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.011 0.0106
Schistosoma mansoni glutamate synthase 0.0013 0.001 0.001
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0013 0.001 0.0004
Giardia lamblia Phosphatidylinositol 4-kinase 0.0048 0.0114 0.0605
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0047 0.011 0.0106
Schistosoma mansoni serine/threonine protein kinase 0.0014 0.0013 0.0017
Schistosoma mansoni axis inhibition protein axin 0.0013 0.0011 0.0013
Echinococcus multilocularis neuropeptides capa receptor 0.0047 0.011 0.0106
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0048 0.0114 0.157
Loa Loa (eye worm) hypothetical protein 0.0019 0.0029 0.0149
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0013 0.0011 0.0041
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0049 0.0117 0.0178
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0049 0.0116 0.0111
Schistosoma mansoni hypothetical protein 0.0013 0.001 0.001
Trypanosoma cruzi cytochrome P450, putative 0.0015 0.0014 0.0016
Echinococcus multilocularis roundabout 2 0.0018 0.0024 0.0019
Echinococcus multilocularis orexin receptor type 2 0.0047 0.011 0.0106
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0102 0.0276 0.0271
Loa Loa (eye worm) hypothetical protein 0.0102 0.0276 0.1668
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0013 0.001 0.0004
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0024 0.0042 0.0228
Schistosoma mansoni nuclear hormone receptor 0.0041 0.0093 0.0174
Trichomonas vaginalis phosphofructokinase, putative 0.015 0.0418 0.2357
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.001 0.0002
Brugia malayi nuclear hormone receptor 0.0019 0.0029 0.0177
Trypanosoma cruzi cytochrome P450, putative 0.0015 0.0014 0.0016
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0041 0.0093 0.0174
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0049 0.0116 0.0296
Schistosoma mansoni glutaminase 0.0558 0.1629 0.3189
Echinococcus granulosus g protein coupled receptor 0.0047 0.011 0.0106
Loa Loa (eye worm) phosphatidylinositol 3 0.0048 0.0114 0.0673
Leishmania major phosphatidylinositol kinase related protein, putative 0.0048 0.0114 0.0291
Onchocerca volvulus 0.0047 0.011 0.0719
Leishmania major 4-coumarate:coa ligase-like protein 0.0016 0.0018 0.0024
Echinococcus multilocularis dna polymerase kappa 0.0013 0.0009 0.0004
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0047 0.011 0.0675
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0012 0.0006 0.0009
Loa Loa (eye worm) hypothetical protein 0.0019 0.0029 0.0149
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0425 0.1233 0.7564
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0041 0.0093 0.0089
Schistosoma mansoni flap endonuclease-1 0.0017 0.002 0.0031
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0122 0.0333 0.1866
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0033 0.0069 0.0898
Loa Loa (eye worm) PXA domain-containing protein 0.0013 0.0011 0.0041
Onchocerca volvulus 0.0047 0.011 0.0719
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0041 0.0093 0.0174
Brugia malayi latrophilin 2 splice variant baaae 0.0046 0.0107 0.0655
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0238 0.0678 0.1853
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0048 0.0114 0.1568
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0597 0.1744 1
Echinococcus multilocularis regulator of G protein signaling 3 0.0013 0.0011 0.0007
Echinococcus granulosus G protein coupled receptor 139 0.0047 0.011 0.0106
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0037 0.008 0.0121
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0016 0.0018 0.0107
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0013 0.001 0.0004
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0013 0.001 0.0002
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0049 0.0116 0.0711
Loa Loa (eye worm) transcription factor SMAD2 0.0079 0.0205 0.1232
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.3377 1 1
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0141 0.0391 0.1102
Brugia malayi G-protein coupled receptor 0.0047 0.011 0.0675
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Leishmania major hypothetical protein, conserved 0.0025 0.0045 0.0099
Echinococcus multilocularis FTZ F1 alpha 0.0041 0.0093 0.0089
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0047 0.011 0.0106
Loa Loa (eye worm) MH2 domain-containing protein 0.0079 0.0205 0.1232
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0014 0.0013 0.0052
Mycobacterium ulcerans Type I modular polyketide synthase 0.0051 0.0122 0.075
Echinococcus multilocularis potassium large conductance calcium activated 0.0093 0.0248 0.0244
Trichomonas vaginalis PIKK family atypical protein kinase 0.0135 0.0373 0.2101
Loa Loa (eye worm) hypothetical protein 0.0013 0.0011 0.0041
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0034 0.0071 0.0323
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0022 0.0036 0.0192
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0013 0.001 0.0014
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.011 0.0106
Echinococcus granulosus hypothetical protein 0.0047 0.011 0.0106
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.004 0.009 0.0085
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0678 0.3855
Mycobacterium tuberculosis Probable fatty acid synthase Fas (fatty acid synthetase) 0.0016 0.0019 0.0028
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.011 0.0207
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.011 0.0207
Echinococcus granulosus transcription factor eb 0.015 0.0415 0.0411
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0597 0.1744 1
Mycobacterium tuberculosis Probable thioesterase TesA 0.0042 0.0097 0.0147
Brugia malayi nuclear receptor RXR 0.0022 0.0036 0.0219
Brugia malayi tailless protein 0.0019 0.0029 0.0177
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0013 0.001 0.0043
Echinococcus multilocularis regulator of G protein signaling 7 0.0013 0.0011 0.0007
Schistosoma mansoni nuclear receptor 0.0019 0.0029 0.0048
Loa Loa (eye worm) acetyltransferase 0.0102 0.0274 0.1658
Echinococcus multilocularis 3 oxoacyl (acyl carrier protein) synthase 0.0013 0.0009 0.0005
Schistosoma mansoni coup transcription factor 0.0041 0.0093 0.0174
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0049 0.0116 0.1597
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0041 0.0093 0.0573
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0048 0.0113 0.0693
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0011 0.0013
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0077 0.0201 0.0554
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0042 0.0095 0.0143
Echinococcus multilocularis nuclear receptor nhr 48 0.0019 0.0029 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0238 0.0678 0.3855
Brugia malayi Flap endonuclease-1 0.0018 0.0026 0.0157
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0013 0.001 0.0058
Loa Loa (eye worm) fatty acid synthase 0.005 0.012 0.0712
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0013 0.001 0.0014
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0597 0.1744 1
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0022 0.0036 0.0156
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0041 0.0092 0.1192
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0041 0.0093 0.0089
Plasmodium vivax hypothetical protein 0.0048 0.0114 0.2824
Trypanosoma brucei hypothetical protein, conserved 0.0048 0.0113 0.1556
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0031 0.0064 0.0116
Trypanosoma brucei pyruvate kinase 1 0.0045 0.0104 0.1419
Brugia malayi PAS domain containing protein 0.0022 0.0036 0.0221
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0226 0.0642 0.0638
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0292 0.0837 0.3805
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0231 0.1278
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0041 0.0093 0.0547
Plasmodium vivax histone acetyltransferase GCN5, putative 0.003 0.006 0.142
Mycobacterium tuberculosis Conserved protein 0.0024 0.0042 0.0063
Echinococcus granulosus microtubule associated protein 2 0.1727 0.5099 0.5097
Echinococcus granulosus regulator of G protein signaling 7 0.0013 0.0011 0.0007
Trichomonas vaginalis phosphofructokinase, putative 0.0041 0.0092 0.0478
Plasmodium falciparum ferrodoxin reductase-like protein 0.0013 0.001 0.0098
Brugia malayi follicle stimulating hormone receptor 0.0047 0.011 0.0675
Mycobacterium ulcerans polyketide synthase MbtC 0.0013 0.0009 0.0055
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0013 0.0009 0.0004
Echinococcus granulosus beta LACTamase domain containing family member 0.0024 0.0042 0.0037
Echinococcus granulosus X box binding protein 1 0.019 0.0535 0.053
Echinococcus multilocularis serine protein kinase ATM 0.0135 0.0373 0.0369
Chlamydia trachomatis 3-oxoacyl-ACP synthase 0.0013 0.0009 0.0045
Trichomonas vaginalis CAMK family protein kinase 0.0193 0.0544 0.3085
Onchocerca volvulus 0.0052 0.0126 0.0832
Plasmodium falciparum glutathione reductase 0.0141 0.0389 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0029 0.0024
Plasmodium vivax hypothetical protein, conserved 0.0048 0.0114 0.2824
Brugia malayi hypothetical protein 0.0019 0.0029 0.0177
Toxoplasma gondii phosphofructokinase PFKII 0.0041 0.0092 0.1238
Mycobacterium tuberculosis Probable polyketide synthase Pks17 0.0012 0.0008 0.0012
Brugia malayi PXA domain containing protein 0.0013 0.0011 0.0069
Brugia malayi acetyltransferase, GNAT family protein 0.0102 0.0274 0.1681
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0013 0.001 0.0005
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0036 0.0061
Loa Loa (eye worm) hypothetical protein 0.0016 0.0018 0.008
Loa Loa (eye worm) neuropeptide F receptor 0.0047 0.011 0.0649
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0029 0.0024
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0013 0.001 0.0007
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0041 0.0093 0.0547
Echinococcus multilocularis somatostatin receptor 0.0047 0.011 0.0106
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0049 0.0116 0.0175
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0238 0.0678 1
Plasmodium vivax ferrodoxin reductase, putative 0.0013 0.001 0.0098
Entamoeba histolytica hypothetical protein 0.0135 0.0373 0.2101
Loa Loa (eye worm) hypothetical protein 0.0041 0.0093 0.0547
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0058 0.0143 0.0771
Echinococcus multilocularis pyruvate kinase 0.0045 0.0104 0.0099
Loa Loa (eye worm) hypothetical protein 0.0062 0.0155 0.0927
Brugia malayi A-kinase anchor protein 10, precursor 0.0013 0.0011 0.0069
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0048 0.0114 0.2824
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0047 0.011 0.0207
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0092 0.0243 0.135
Echinococcus granulosus serine protein kinase ATM 0.0135 0.0373 0.0369
Mycobacterium leprae PROBABLE CONSERVED LIPOPROTEIN LPQF 0.0087 0.0229 0.104
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0019 0.0029 0.0024
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0013 0.001 0.0002
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0107 0.029 0.1782
Schistosoma mansoni calcium-activated potassium channel 0.0025 0.0045 0.0079
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0013 0.001 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0156
Schistosoma mansoni biogenic amine receptor 0.0047 0.011 0.0207
Mycobacterium ulcerans fatty acid synthase Fas 0.0016 0.0019 0.0114
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0047 0.011 0.0106
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0013 0.001 0.0004
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0013 0.001 0.0058
Echinococcus granulosus flap endonuclease 1 0.0018 0.0026 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0041 0.0093 0.0573
Toxoplasma gondii pyruvate kinase PyKII 0.0023 0.0039 0.0451
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0013 0.001 0.0058
Trichomonas vaginalis phosphofructokinase, putative 0.015 0.0418 0.2357
Trypanosoma brucei calcium/potassium channel (CAKC), putative 0.0025 0.0045 0.0536
Loa Loa (eye worm) glutathione reductase 0.0141 0.0389 0.2364
Echinococcus granulosus axis inhibition protein axin 0.0013 0.0011 0.0007
Echinococcus granulosus regulator of G protein signaling 3 0.0013 0.0011 0.0007
Echinococcus multilocularis flap endonuclease 1 0.0018 0.0026 0.0021
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0022 0.0036 0.0156
Entamoeba histolytica thioredoxin reductase, putative 0.0013 0.001 0.0004
Loa Loa (eye worm) twinkle helicase 0.0073 0.0187 0.1124
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0013 0.0011 0.0013
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0058 0.0143 0.0771
Brugia malayi Melatonin receptor type 1A 0.0047 0.011 0.0675
Schistosoma mansoni nuclear receptor nhr-48 0.0019 0.0029 0.0048
Brugia malayi G-protein coupled receptor 0.0047 0.011 0.0675
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0058 0.0143 0.1998
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Leishmania major ATP-dependent phosphofructokinase 0.015 0.0418 0.1133
Echinococcus multilocularis regulator of G protein signaling 7 0.0013 0.0011 0.0007
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0013 0.001 0.0005
Loa Loa (eye worm) phosphofructokinase 0.015 0.0418 0.2544
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0048 0.0113 0.28
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0058 0.0143 0.0876
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.0093 0.0573
Leishmania major protein kinase, putative 0.0022 0.0038 0.008
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0047 0.011 0.0106
Trypanosoma cruzi DNA repair protein, putative 0.0022 0.0036 0.0079
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0013 0.001 0.0058
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0048 0.0114 0.0605
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0054 0.0131 0.0807
Echinococcus granulosus FTZ F1 alpha 0.0041 0.0093 0.0089
Brugia malayi neuropeptide F receptor 0.0047 0.011 0.0675
Giardia lamblia Methyltransferase like 2 0.0015 0.0017 0.0045
Brugia malayi GnHR receptor homolog 0.0047 0.011 0.0675
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0024 0.0042 0.0063
Trichomonas vaginalis glutamate synthase, putative 0.0013 0.001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0086 0.0227 0.1367
Loa Loa (eye worm) 6-phosphofructokinase 0.015 0.0418 0.2544
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0048 0.0114 0.2824
Onchocerca volvulus 0.0024 0.0042 0.0229
Onchocerca volvulus 0.0047 0.011 0.0719
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0015 0.0014 0.0089
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0021 0.0034 0.0029
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0013 0.001 0.0005
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0013 0.001 0.0002
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0041 0.0093 0.0547
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0013 0.001 0.0004
Loa Loa (eye worm) G-protein coupled receptor 0.0047 0.011 0.0649
Brugia malayi hypothetical protein 0.0022 0.0036 0.0219
Loa Loa (eye worm) hypothetical protein 0.0047 0.011 0.0649
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0023 0.0039 0.0034
Plasmodium vivax pyruvate kinase, putative 0.0045 0.0104 0.256
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0119
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0029 0.0057 0.0086

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.05 uM Inhibition of platelet-derived growth factor receptor beta phosphorylation was measured in intact cells using a two-site enzyme linked immunosorbent assay (ELISA) ChEMBL. 14584942
IC50 (binding) = 0.05 uM Inhibition of platelet-derived growth factor receptor beta phosphorylation was measured in intact cells using a two-site enzyme linked immunosorbent assay (ELISA) ChEMBL. 14584942

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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