Detailed information for compound 280796

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 279.785 | Formula: C15H20ClN2O-
  • H donors: 1 H acceptors: 2 LogP: 3.26 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCC(c1ccc(cc1)C(Cn1cncc1)O)C.[Cl-]
  • InChi: 1S/C15H20N2O.ClH/c1-3-12(2)13-4-6-14(7-5-13)15(18)10-17-9-8-16-11-17;/h4-9,11-12,15,18H,3,10H2,1-2H3;1H/p-1
  • InChiKey: WRXFXMSPVDMHIR-UHFFFAOYSA-M  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus adenylate cyclase type IX 0.0117 0.0474 0.0473
Schistosoma mansoni hypothetical protein 0.0312 0.1405 0.1405
Trypanosoma cruzi cytochrome P450, putative 0.0051 0.0159 0.1005
Schistosoma mansoni adenoreceptor 0.071 0.3298 0.3298
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0136 0.1551
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0066 0.0229 0.213
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0086 0.0328 0.0536
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Brugia malayi Melatonin receptor type 1A 0.071 0.3298 0.6149
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0018 0.0002 0.0012
Brugia malayi cytoplasmic intermediate filament protein 0.0061 0.0207 0.0385
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0034 0.0077 0.0787
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0166 0.0706 0.4447
Entamoeba histolytica hypothetical protein 0.0021 0.0018 0.0212
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0048 0.0143 0.0266
Schistosoma mansoni rhodopsin-like orphan GPCR 0.071 0.3298 0.3298
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0066 0.0229 0.213
Plasmodium falciparum glutathione reductase 0.0034 0.008 0.2757
Loa Loa (eye worm) nuclear hormone receptor 0.0117 0.0473 0.0881
Mycobacterium tuberculosis Probable lipase LipD 0.0112 0.045 0.1313
Loa Loa (eye worm) hypothetical protein 0.0034 0.0081 0.015
Schistosoma mansoni inositol monophosphatase 0.0035 0.0082 0.0081
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0035 0.0082 0.0514
Echinococcus granulosus survival motor neuron protein 1 0.0435 0.1989 0.1989
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0115 0.0465 0.293
Toxoplasma gondii ribosomal protein RPL19 0.0024 0.003 0.0277
Loa Loa (eye worm) cytochrome P450 family protein 0.0051 0.0159 0.0297
Schistosoma mansoni rab6-interacting 0.0022 0.0019 0.0019
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0034 0.0077 0.0787
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0028
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0034 0.0077 0.0185
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.0084
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0066 0.0229 0.213
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0086 0.0328 0.0536
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0243 0.1074 0.6779
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0023 0.0024 0.014
Mycobacterium leprae Probable lipase LipE 0.0112 0.045 0.8666
Onchocerca volvulus 0.1301 0.6115 1
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0035 0.0082 0.0985
Loa Loa (eye worm) calpain family protein 1 0.0061 0.0205 0.0381
Trypanosoma cruzi hypothetical protein, conserved 0.0112 0.045 0.2842
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0048 0.0143 0.0143
Echinococcus multilocularis g protein coupled receptor 0.071 0.3298 0.3298
Plasmodium vivax hypothetical protein, conserved 0.0112 0.045 0.4192
Schistosoma mansoni rhodopsin-like orphan GPCR 0.071 0.3298 0.3298
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0024 0.0152
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0126 0.0517 0.1516
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0023 0.0024 0.0825
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1143 0.5363 1
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0066 0.0229 0.0374
Trypanosoma cruzi kinesin, putative 0.0018 0.0002 0.0012
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0087 0.0333 0.0958
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0034 0.0077 0.0185
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0123 0.0501 0.082
Schistosoma mansoni hypothetical protein 0.0145 0.0605 0.0605
Trichomonas vaginalis conserved hypothetical protein 0.0123 0.0501 0.082
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0189 0.0309
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0034 0.0077 0.0185
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.0084
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0079 0.0129
Toxoplasma gondii aldehyde dehydrogenase 0.0158 0.0668 0.622
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0123 0.0501 0.082
Loa Loa (eye worm) cytochrome P450 0.0034 0.0077 0.0142
Schistosoma mansoni jumonji domain containing protein 0.0059 0.0198 0.0197
Echinococcus granulosus histone acetyltransferase KAT2B 0.0284 0.1269 0.1269
Schistosoma mansoni hypothetical protein 0.0191 0.0827 0.0827
Echinococcus multilocularis somatostatin receptor 0.071 0.3298 0.3298
Schistosoma mansoni hypothetical protein 0.0145 0.0605 0.0605
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0086 0.0328 0.0328
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0112 0.045 0.1313
Echinococcus multilocularis transfer RNA-Lys 0.0039 0.0101 0.0101
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0126 0.0517 0.3264
Loa Loa (eye worm) hypothetical protein 0.0025 0.0036 0.0067
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0123 0.0501 0.082
Brugia malayi hypothetical protein 0.0051 0.0157 0.0293
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0015 0.0025
Brugia malayi conserved hypotetical protein 0.0022 0.0023 0.0043
Brugia malayi neuropeptide F receptor 0.071 0.3298 0.6149
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2108 0.9961 0.9961
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Brugia malayi nuclear receptor NHR-88 0.0048 0.0143 0.0266
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0034 0.0077 0.0185
Schistosoma mansoni rhodopsin-like orphan GPCR 0.071 0.3298 0.3298
Brugia malayi GnHR receptor homolog 0.071 0.3298 0.6149
Loa Loa (eye worm) transcription factor SMAD2 0.0608 0.2812 0.5245
Brugia malayi MH2 domain containing protein 0.0019 0.0004 0.0008
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0072 0.017
Leishmania major cytochrome p450-like protein 0.0034 0.0077 0.0482
Schistosoma mansoni hypothetical protein 0.0329 0.1483 0.1483
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.071 0.3298 0.3298
Plasmodium vivax glutathione reductase, putative 0.0034 0.008 0.0747
Schistosoma mansoni amine GPCR 0.071 0.3298 0.3298
Plasmodium falciparum 60S ribosomal protein L19 0.0024 0.003 0.1021
Onchocerca volvulus 0.0297 0.1332 0.2179
Mycobacterium tuberculosis Probable reductase 0.0079 0.0291 0.0832
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0123 0.0501 0.082
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0015 0.0096
Brugia malayi MAP kinase sur-1 0.0115 0.0465 0.0866
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0046 0.0136 0.0254
Echinococcus granulosus allatostatin A receptor 0.071 0.3298 0.3298
Echinococcus multilocularis inositol monophosphatase 1 0.0035 0.0082 0.0081
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0023 0.0024 0.0045
Leishmania major cathepsin L-like protease 0.0067 0.0236 0.1489
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0048 0.0143 0.0266
Echinococcus multilocularis 0.0034 0.0077 0.0076
Loa Loa (eye worm) 6-phosphofructokinase 0.0126 0.0517 0.0965
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0021 0.0018 0.0008
Brugia malayi TAR-binding protein 0.0197 0.0856 0.1596
Schistosoma mansoni biogenic amine receptor 0.071 0.3298 0.3298
Brugia malayi hypothetical protein 0.071 0.3298 0.6149
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0066 0.0229 0.0229
Trichomonas vaginalis 60S ribosomal protein L19, putative 0.0024 0.003 0.0049
Brugia malayi Latrophilin receptor protein 2 0.0145 0.0605 0.1128
Brugia malayi hypothetical protein 0.0033 0.0072 0.0134
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0066 0.0229 0.0374
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.071 0.3298 0.3298
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0048 0.0143 0.0143
Trichomonas vaginalis 60S ribosomal protein L19, putative 0.0024 0.003 0.0049
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0015 0.0028
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0043
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.071 0.3298 0.3298
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0091 0.0349 0.3245
Brugia malayi Dopamine receptor 0.071 0.3298 0.6149
Echinococcus granulosus rhodopsin orphan GPCR 0.071 0.3298 0.3298
Loa Loa (eye worm) hypothetical protein 0.012 0.0486 0.0905
Onchocerca volvulus 0.071 0.3298 0.5393
Echinococcus multilocularis serotonin receptor 0.071 0.3298 0.3298
Onchocerca volvulus 0.071 0.3298 0.5393
Echinococcus granulosus biogenic amine 5HT receptor 0.071 0.3298 0.3298
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0064 0.0219 0.0219
Brugia malayi glutathione reductase 0.0034 0.008 0.015
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0022 0.0023 0.0023
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0034 0.0077 0.0185
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0153 0.0646 0.0646
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0035 0.0083 0.052
Leishmania major phosphopantetheinyl transferase-like protein 0.0021 0.0018 0.0111
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0055 0.0178 0.0178
Brugia malayi beta-lactamase family protein 0.0112 0.045 0.084
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0115 0.0465 0.293
Loa Loa (eye worm) 6-phosphofructokinase 0.0126 0.0517 0.0965
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.071 0.3298 0.3298
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0165 0.0704 0.6554
Echinococcus granulosus mitogen activated protein kinase 0.0115 0.0465 0.0464
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0048 0.0143 0.0266
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0123 0.0501 0.0501
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0243 0.1074 0.6779
Leishmania major cathepsin L-like protease 0.0067 0.0236 0.1489
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0015 0.0025
Entamoeba histolytica 60S ribosomal protein L19, putative 0.0024 0.003 0.036
Brugia malayi Inositol-1 0.0035 0.0082 0.0152
Echinococcus multilocularis G-protein coupled receptor, putative 0.071 0.3298 0.3298
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0034 0.0077 0.0787
Onchocerca volvulus Protein ultraspiracle homolog 0.0048 0.0143 0.0233
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0123 0.0501 0.082
Loa Loa (eye worm) hypothetical protein 0.0066 0.0229 0.0427
Schistosoma mansoni hypothetical protein 0.0089 0.0339 0.0339
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0034 0.0076 0.0076
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0048 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Echinococcus granulosus lamin 0.0114 0.0458 0.0458
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0.0019 0.0019
Brugia malayi hypothetical protein 0.0022 0.0023 0.0043
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0034 0.0076 0.048
Trypanosoma cruzi trypanothione reductase, putative 0.0034 0.008 0.0507
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0049 0.0151 0.094
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0123 0.0501 0.082
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Loa Loa (eye worm) hypothetical protein 0.0176 0.0755 0.1407
Schistosoma mansoni rhodopsin-like orphan GPCR 0.071 0.3298 0.3298
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0066 0.0229 0.0374
Loa Loa (eye worm) hypothetical protein 0.0201 0.0873 0.1627
Echinococcus multilocularis sex peptide receptor 0.071 0.3298 0.3298
Echinococcus multilocularis allatostatin A receptor 0.071 0.3298 0.3298
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.071 0.3298 0.3298
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.071 0.3298 0.3298
Echinococcus granulosus tm gpcr rhodopsin 0.071 0.3298 0.3298
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0123 0.0501 0.082
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0066 0.0229 0.1434
Onchocerca volvulus 0.0039 0.0101 0.0165
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0048 0.0143 0.0266
Brugia malayi Bromodomain containing protein 0.0167 0.0712 0.1327
Echinococcus granulosus TGF beta signal transducer SmadC 0.0041 0.0114 0.0113
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0041 0.0114 0.0113
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0048 0.0143 0.0143
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0048 0.0143 0.0266
Onchocerca volvulus 0.0022 0.0019 0.0031
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0019 0.0019
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0123 0.0501 0.082
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0091 0.0349 0.3245
Brugia malayi phosphofructokinase 0.0126 0.0517 0.0965
Trypanosoma brucei hypothetical protein, conserved 0.0021 0.0018 0.0099
Brugia malayi 6-phosphofructokinase 0.0126 0.0517 0.0965
Echinococcus granulosus calpain A 0.0064 0.0219 0.0219
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0243 0.1074 1
Echinococcus multilocularis g-protein coupled receptor 0.071 0.3298 0.3298
Brugia malayi MH1 domain containing protein 0.0023 0.0025 0.0047
Brugia malayi Importin beta-1 subunit 0.0031 0.0063 0.0117
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0023 0.0024 0.0197
Onchocerca volvulus 0.071 0.3298 0.5393
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0035 0.0083 0.0082
Echinococcus multilocularis biogenic amine (5HT) receptor 0.071 0.3298 0.3298
Echinococcus granulosus neuropeptide receptor 0.071 0.3298 0.3298
Echinococcus multilocularis beta LACTamase domain containing family member 0.0112 0.045 0.045
Echinococcus granulosus mothers against decapentaplegic 6 0.0019 0.0004 0.0004
Schistosoma mansoni biogenic amine (5HT) receptor 0.071 0.3298 0.3298
Loa Loa (eye worm) hypothetical protein 0.0053 0.0168 0.0313
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0034 0.0077 0.0787
Brugia malayi RE15519p 0.071 0.3298 0.6149
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0034 0.0077 0.0787
Echinococcus granulosus tachykinin peptides receptor 99D 0.071 0.3298 0.3298
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0061 0.0208 0.1314
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0123 0.0501 0.082
Loa Loa (eye worm) isocitrate dehydrogenase 0.0035 0.0083 0.0154
Echinococcus multilocularis ribosomal protein L19 0.0024 0.003 0.003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.071 0.3298 0.3298
Loa Loa (eye worm) MH2 domain-containing protein 0.0019 0.0004 0.0008
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0123 0.0501 0.082
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0243 0.1074 0.6775
Entamoeba histolytica 60S ribosomal protein L19, putative 0.0024 0.003 0.036
Echinococcus multilocularis tachykinin peptides receptor 99D 0.071 0.3298 0.3298
Echinococcus granulosus muscleblind protein 0.0398 0.1813 0.1813
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.071 0.3298 0.3298
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0035 0.0082 0.0514
Mycobacterium ulcerans aldehyde dehydrogenase 0.0158 0.0668 0.8374
Loa Loa (eye worm) thioredoxin reductase 0.0034 0.008 0.015
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0135 0.0561 0.0561
Loa Loa (eye worm) hypothetical protein 0.008 0.0295 0.055
Leishmania major 60S ribosomal protein L19, putative 0.0024 0.003 0.0188
Loa Loa (eye worm) hypothetical protein 0.0048 0.0143 0.0266
Entamoeba histolytica acetyltransferase, GNAT family 0.0079 0.0291 0.3522
Echinococcus granulosus calpain 7 C02 family 0.0018 0.0002 0.0002
Trypanosoma cruzi cysteine peptidase, putative 0.0067 0.0236 0.1489
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0066 0.0229 0.7858
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0297 0.1331 0.1331
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0034 0.0077 0.0787
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0189 0.0309
Loa Loa (eye worm) hypothetical protein 0.0051 0.0157 0.0293
Brugia malayi hypothetical protein 0.071 0.3298 0.6149
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0025 0.0036 0.0036
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0031 0.0064 0.0978
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0051 0.016 0.016
Brugia malayi hypothetical protein 0.0435 0.1989 0.371
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0112 0.045 0.045
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Trichomonas vaginalis bromodomain-containing protein, putative 0.0091 0.0349 0.0571
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0034 0.0077 0.0185
Brugia malayi nuclear hormone receptor family member odr-7 0.0022 0.0023 0.0043
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0126 0.0517 0.3256
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0066 0.0229 0.1444
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0236 0.1479
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0157 0.1464
Echinococcus granulosus GPCR family 2 0.0145 0.0605 0.0605
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0019 0.0019
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0035 0.0083 0.0082
Leishmania major kinesin, putative 0.0018 0.0002 0.0012
Schistosoma mansoni opsin-like receptor 0.071 0.3298 0.3298
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Onchocerca volvulus 0.071 0.3298 0.5393
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Loa Loa (eye worm) hypothetical protein 0.0112 0.045 0.084
Schistosoma mansoni tar DNA-binding protein 0.0197 0.0856 0.0856
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0034 0.0081 0.0197
Entamoeba histolytica calpain large subunit domain III containing protein 0.0018 0.0002 0.0023
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0022 0.0023 0.0023
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0066 0.0229 0.213
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0135 0.0561 0.0561
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0034 0.0077 0.0787
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0076 0.0277 0.0517
Brugia malayi calpain 7 0.0018 0.0002 0.0003
Loa Loa (eye worm) doublecortin family protein 0.0022 0.0019 0.0036
Loa Loa (eye worm) hypothetical protein 0.01 0.0392 0.0732
Echinococcus granulosus snurportin 1 0.0329 0.1483 0.1483
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0142 0.0592 0.0592
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0243 0.1074 1
Brugia malayi steroid hormone receptor 0.0048 0.0143 0.0266
Echinococcus granulosus neuropeptide receptor 0.071 0.3298 0.3298
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0123 0.0501 0.082
Schistosoma mansoni lamin 0.0114 0.0458 0.0458
Mycobacterium ulcerans beta-lactamase 0.0112 0.045 0.5581
Loa Loa (eye worm) hypothetical protein 0.0024 0.003 0.0055
Schistosoma mansoni inositol monophosphatase 0.0035 0.0082 0.0081
Trypanosoma cruzi cysteine peptidase, putative 0.0067 0.0236 0.1489
Onchocerca volvulus 0.0022 0.0019 0.0031
Trypanosoma brucei 60S ribosomal protein L19, putative 0.0024 0.003 0.0176
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0024 0.0031 0.0031
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0015 0.0084
Loa Loa (eye worm) adenylyl cyclase 3 0.0197 0.0853 0.1591
Schistosoma mansoni aldehyde dehydrogenase 0.0158 0.0668 0.0668
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0023 0.0024 0.0224
Schistosoma mansoni cpg binding protein 0.0078 0.0286 0.0286
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0066 0.0229 0.0374
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Loa Loa (eye worm) G-protein coupled receptor 0.071 0.3298 0.6149
Echinococcus granulosus nuclear receptor nhr 48 0.0022 0.0023 0.0023
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0015 0.0025
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0165 0.0704 0.0704
Echinococcus multilocularis neuropeptides capa receptor 0.071 0.3298 0.3298
Schistosoma mansoni transcription factor LCR-F1 0.0191 0.0827 0.0827
Echinococcus multilocularis mothers against decapentaplegic 5 0.0041 0.0114 0.0113
Brugia malayi nuclear receptor NHR-67 0.0022 0.0023 0.0043
Mycobacterium tuberculosis Conserved protein 0.0112 0.045 0.1313
Brugia malayi RNA, U transporter 1 0.0088 0.0334 0.0622
Brugia malayi Pre-SET motif family protein 0.1143 0.5363 1
Echinococcus multilocularis tar DNA binding protein 0.0197 0.0856 0.0856
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0051 0.0159 0.185
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.0084
Schistosoma mansoni calpain (C02 family) 0.0018 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.0112 0.045 0.2842
Loa Loa (eye worm) hypothetical protein 0.0048 0.0143 0.0266
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0019 0.0019
Giardia lamblia Histone acetyltransferase GCN5 0.0079 0.0291 0.6144
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0002 0.0012
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0034 0.0076 0.0142
Loa Loa (eye worm) histone methyltransferase 0.003 0.0059 0.011
Loa Loa (eye worm) MH2 domain-containing protein 0.0041 0.0114 0.0211
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0035 0.0083 0.0508
Loa Loa (eye worm) hypothetical protein 0.0112 0.045 0.084
Plasmodium falciparum importin beta, putative 0.0031 0.0063 0.2156
Leishmania major DNA polymerase kappa, putative 0.0021 0.0015 0.0096
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0153 0.0646 0.0646
Schistosoma mansoni loxhd1 0.0022 0.0019 0.0019
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0035 0.0082 0.0514
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0123 0.0501 0.3163
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0236 0.1479
Brugia malayi hypothetical protein 0.071 0.3298 0.6149
Onchocerca volvulus 0.071 0.3298 0.5393
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0189 0.0309
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0112 0.045 0.1313
Onchocerca volvulus 0.0043 0.0119 0.0194
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.071 0.3298 0.3298
Schistosoma mansoni cellular tumor antigen P53 0.0297 0.1332 0.1332
Trichomonas vaginalis phosphofructokinase, putative 0.0126 0.0517 0.0846
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0049 0.0151 0.0951
Giardia lamblia Ribosomal protein L19 0.0024 0.003 0.0325
Echinococcus granulosus thyrotropin releasing hormone receptor 0.071 0.3298 0.3298
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0035 0.0082 0.0758
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0079 0.0291 0.0832
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0043
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0136 0.1551
Onchocerca volvulus 0.0022 0.0023 0.0038
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0046 0.0136 0.1551
Entamoeba histolytica protein kinase, putative 0.0019 0.0007 0.0083
Mycobacterium ulcerans hypothetical protein 0.0184 0.0795 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.071 0.3298 0.3298
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0061 0.0205 0.0205
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0115 0.0465 0.293
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Echinococcus multilocularis rhodopsin orphan GPCR 0.071 0.3298 0.3298
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0034 0.0076 0.048
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0066 0.0229 0.213
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0041 0.0114 0.0113
Loa Loa (eye worm) phosphofructokinase 0.0126 0.0517 0.0965
Schistosoma mansoni Mername-AA248 (C02 family) 0.0018 0.0002 0.0002
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0112 0.045 0.084
Echinococcus granulosus neuropeptide FF receptor 2 0.071 0.3298 0.3298
Schistosoma mansoni cytochrome P450 0.0034 0.0077 0.0076
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0136 0.0254
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0124 0.0506 0.0505
Echinococcus multilocularis mothers against decapentaplegic 2 0.0019 0.0004 0.0004
Schistosoma mansoni biogenic amine (dopamine) receptor 0.071 0.3298 0.3298
Brugia malayi calpain family protein 1 0.0061 0.0205 0.0381
Brugia malayi ORL1-like opioid receptor 0.071 0.3298 0.6149
Echinococcus multilocularis rhodopsin orphan GPCR 0.071 0.3298 0.3298
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0048 0.0143 0.0266
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0066 0.0229 0.213
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0023 0.0024 0.0024
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0034 0.0077 0.0787
Brugia malayi Intermediate filament tail domain containing protein 0.0114 0.0458 0.0854
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0123 0.0501 0.3155
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0066 0.0229 0.0427
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0015 0.0096
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.0084
Onchocerca volvulus 0.071 0.3298 0.5393
Schistosoma mansoni smad1 5 8 and 0.0041 0.0114 0.0113
Trypanosoma cruzi cytochrome P450, putative 0.0051 0.0159 0.1005
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0123 0.0501 0.082
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0066 0.0229 0.0229
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0243 0.1074 0.6779
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0086 0.0328 0.0328
Echinococcus granulosus g protein coupled receptor 0.071 0.3298 0.3298
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0136 0.0254
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0035 0.0083 0.052
Echinococcus granulosus inositol monophosphatase 1 0.0035 0.0082 0.0081
Schistosoma mansoni importin beta-1 0.0031 0.0063 0.0063
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0048 0.0143 0.0266
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0022 0.0023 0.0043
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0035 0.0083 0.052
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0034 0.0077 0.0787
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0022 0.0023 0.0038
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0123 0.0501 0.082
Brugia malayi Adenylyl cyclase protein 0.0083 0.0313 0.0583
Echinococcus multilocularis microtubule associated protein 2 0.2117 1 1
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0076 0.0277 0.0277
Brugia malayi Doublecortin family protein 0.0022 0.0019 0.0036
Onchocerca volvulus 0.071 0.3298 0.5393
Mycobacterium ulcerans hypothetical protein 0.0046 0.0136 0.1551
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0034 0.0077 0.0787
Echinococcus multilocularis musashi 0.0114 0.0458 0.0458
Echinococcus multilocularis neuropeptide s receptor 0.1107 0.519 0.519
Echinococcus multilocularis rhodopsin orphan GPCR 0.071 0.3298 0.3298
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0034 0.0077 0.0185
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.006 0.0202 0.1275
Plasmodium vivax thioredoxin reductase, putative 0.0034 0.008 0.0747
Loa Loa (eye worm) hypothetical protein 0.0022 0.0019 0.0036
Echinococcus granulosus thioredoxin glutathione reductase 0.0035 0.0083 0.0082
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0145 0.0605 0.0605
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0015 0.0015
Echinococcus granulosus methyl CpG binding domain protein 2 0.0035 0.0085 0.0084
Loa Loa (eye worm) hypothetical protein 0.0083 0.0313 0.0583
Entamoeba histolytica acyl-coA synthetase, putative 0.0046 0.0136 0.1644
Loa Loa (eye worm) hypothetical protein 0.0112 0.045 0.084
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0142 0.0592 0.0592
Schistosoma mansoni rhodopsin-like orphan GPCR 0.071 0.3298 0.3298
Schistosoma mansoni biogenic amine (5HT) receptor 0.071 0.3298 0.3298
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0046 0.0136 0.0365
Brugia malayi nuclear receptor RXR 0.0025 0.0036 0.0067
Echinococcus granulosus calpain 0.0018 0.0002 0.0002
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0015 0.0015
Onchocerca volvulus 0.0089 0.0339 0.0554
Loa Loa (eye worm) hypothetical protein 0.0043 0.0119 0.0221
Schistosoma mansoni survival motor neuron protein 0.0089 0.0339 0.0339
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0153 0.0646 0.1204
Echinococcus granulosus importin subunit beta 1 0.0031 0.0063 0.0063
Schistosoma mansoni growth hormone secretagogue receptor 0.071 0.3298 0.3298
Loa Loa (eye worm) hypothetical protein 0.008 0.0296 0.0552
Onchocerca volvulus 0.0048 0.0143 0.0233
Trypanosoma cruzi 60S ribosomal protein L19, putative 0.0024 0.003 0.0188
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0034 0.0077 0.0787
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0048 0.0143 0.0143
Loa Loa (eye worm) calpain 0.0018 0.0002 0.0003
Echinococcus granulosus ribosomal protein L19 0.0024 0.003 0.003
Schistosoma mansoni hypothetical protein 0.0452 0.2068 0.2068
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0035 0.0085 0.0084
Schistosoma mansoni rab6-interacting 0.0022 0.0019 0.0019
Schistosoma mansoni coup transcription factor 0.0048 0.0143 0.0143
Mycobacterium tuberculosis Probable lipase LipE 0.0112 0.045 0.1313
Echinococcus granulosus intermediate filament protein 0.0114 0.0458 0.0458
Trichomonas vaginalis penicillin-binding protein, putative 0.0112 0.045 0.0737
Leishmania major cytochrome p450-like protein 0.0034 0.0077 0.0482
Giardia lamblia hypothetical protein 0.0066 0.0229 0.4756
Giardia lamblia Hypothetical protein 0.0066 0.0229 0.4756
Toxoplasma gondii ABC1 family protein 0.0112 0.045 0.4192
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0015 0.0096
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0023 0.0023
Onchocerca volvulus 0.0114 0.0458 0.0749
Loa Loa (eye worm) calpain family protein 1 0.0043 0.0119 0.0221
Brugia malayi PHD-finger family protein 0.0063 0.0217 0.0405
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0236 0.1479
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0158 0.0668 0.1971
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0034 0.0079 0.9699
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.063 0.2919 0.2919
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0158 0.0668 0.0667
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Trypanosoma brucei ISWI complex protein 0.0032 0.0067 0.0412
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.003 0.0059 0.0059
Echinococcus multilocularis adenylate cyclase type IX 0.0117 0.0474 0.0473
Echinococcus multilocularis rhodopsin orphan GPCR 0.071 0.3298 0.3298
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.063 0.2919 0.2919
Echinococcus multilocularis calpain 5 0.0018 0.0002 0.0002
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0072 0.017
Loa Loa (eye worm) hypothetical protein 0.0112 0.045 0.084
Echinococcus granulosus tm gpcr rhodopsin 0.071 0.3298 0.3298
Plasmodium falciparum phosphodiesterase gamma, putative 0.0066 0.0229 0.7858
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0123 0.0501 0.3163
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0034 0.0077 0.0185
Trichomonas vaginalis CMGC family protein kinase 0.0115 0.0465 0.076
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0034 0.0079 0.0949
Toxoplasma gondii HEAT repeat-containing protein 0.0031 0.0063 0.0584
Schistosoma mansoni single-minded 0.0052 0.0166 0.0166
Schistosoma mansoni ran 0.0023 0.0024 0.0024
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0079 0.0291 0.0832
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.071 0.3298 0.6149
Brugia malayi beta-lactamase family protein 0.0112 0.045 0.084
Onchocerca volvulus 0.071 0.3298 0.5393
Loa Loa (eye worm) hypothetical protein 0.0061 0.0205 0.0381
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0035 0.0082 0.0133
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0024 0.0031 0.0031
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0086 0.0328 0.0328
Brugia malayi hypothetical protein 0.0176 0.0755 0.1407
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0236 0.1479
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0145 0.0605 0.0605
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0059 0.0198 0.0197
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0123 0.0501 0.082
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0031 0.0064 0.0148
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0034 0.0077 0.0482
Trypanosoma brucei DNA polymerase eta, putative 0.0021 0.0015 0.0084
Schistosoma mansoni microtubule-associated protein tau 0.2117 1 1
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0066 0.0229 0.0427
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0153 0.0646 0.0646
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0297 0.1331 0.1331
Schistosoma mansoni smad1 5 8 and 0.0041 0.0114 0.0113
Mycobacterium leprae putative cytochrome p450 0.0034 0.0077 0.1221
Echinococcus multilocularis thioredoxin glutathione reductase 0.0035 0.0083 0.0082
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0025 0.0037 0.0037
Echinococcus multilocularis rhodopsin orphan GPCR 0.071 0.3298 0.3298
Loa Loa (eye worm) calpain 5 0.0018 0.0002 0.0003
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0034 0.0076 0.9172
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0123 0.0501 0.082
Brugia malayi Cytochrome P450 family protein 0.0093 0.0361 0.0672
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.071 0.3298 0.3298
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0022 0.0023 0.0038
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Schistosoma mansoni biogenic amine receptor 0.071 0.3298 0.3298
Echinococcus granulosus dnaJ subfamily B 0.1106 0.5185 0.5185
Loa Loa (eye worm) hypothetical protein 0.0076 0.0277 0.0517
Toxoplasma gondii isocitrate dehydrogenase 0.0035 0.0083 0.0767
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0048 0.0143 0.0266
Echinococcus granulosus histone lysine methyltransferase setb 0.0201 0.0873 0.0873
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0034 0.0077 0.0185
Echinococcus granulosus biogenic amine 5HT receptor 0.071 0.3298 0.3298
Trypanosoma brucei protein kinase, putative 0.0115 0.0465 0.2922
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Brugia malayi nuclear receptor NHR-88 0.0022 0.0023 0.0043
Brugia malayi gonadotropin-releasing hormone receptor 2 0.071 0.3298 0.6149
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.071 0.3298 0.3298
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0034 0.0077 0.0185
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0043 0.0119 0.0221
Echinococcus granulosus sex peptide receptor 0.071 0.3298 0.3298
Entamoeba histolytica acyl-CoA synthetase, putative 0.0046 0.0136 0.1644
Mycobacterium tuberculosis Conserved hypothetical protein 0.0184 0.0795 0.2353
Loa Loa (eye worm) hypothetical protein 0.0048 0.0143 0.0266
Echinococcus multilocularis neuropeptides capa receptor 0.071 0.3298 0.3298
Echinococcus multilocularis lysine specific demethylase 5A 0.0059 0.0198 0.0197
Echinococcus multilocularis orexin receptor type 2 0.071 0.3298 0.3298
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.071 0.3298 0.3298
Schistosoma mansoni neuropeptide F-like receptor 0.071 0.3298 0.3298
Loa Loa (eye worm) hypothetical protein 0.0061 0.0205 0.0381
Schistosoma mansoni amine GPCR 0.071 0.3298 0.3298
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0072 0.017
Brugia malayi hypothetical protein 0.071 0.3298 0.6149
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0002 0.0012
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0034 0.0079 0.2695
Brugia malayi MH2 domain containing protein 0.0041 0.0114 0.0211
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0024 0.0152
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.071 0.3298 0.3298
Treponema pallidum exodeoxyribonuclease (exoA) 0.0034 0.0076 0.1172
Onchocerca volvulus 0.0078 0.0286 0.0468
Brugia malayi cytochrome P450 0.0034 0.0077 0.0142
Loa Loa (eye worm) hypothetical protein 0.0368 0.1671 0.3116
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0021 0.0018 0.0163
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Trichomonas vaginalis D-aminoacylase, putative 0.0112 0.045 0.0737
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.071 0.3298 0.6149
Loa Loa (eye worm) PHD-finger family protein 0.0043 0.012 0.0223
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0023 0.0023
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0066 0.0229 0.0374
Loa Loa (eye worm) cytochrome P450 family protein 0.0093 0.0361 0.0672
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0022 0.0023 0.0023
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0035 0.0221
Schistosoma mansoni DNA polymerase eta 0.0021 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0043
Schistosoma mansoni zinc finger protein 0.0052 0.0165 0.0165
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0066 0.0229 0.213
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0066 0.0229 0.0229
Brugia malayi photoreceptor-specific nuclear receptor 0.026 0.1155 0.2154
Echinococcus granulosus 7tm_1 domain containing protein 0.071 0.3298 0.3298
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.035 0.1585 1
Schistosoma mansoni hypothetical protein 0.071 0.3298 0.3298
Brugia malayi Nuclear hormone receptor-like 1 0.0025 0.0036 0.0067
Echinococcus granulosus ribosomal protein L19 0.0024 0.003 0.003
Echinococcus granulosus neuropeptide s receptor 0.1107 0.519 0.519
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0048 0.0143 0.0266
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0025 0.0037 0.0037
Brugia malayi jmjC domain containing protein 0.0059 0.0198 0.0368
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Schistosoma mansoni neuropeptide receptor 0.071 0.3298 0.3298
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0022 0.0023 0.0023
Echinococcus granulosus neuropeptide Y receptor 0.071 0.3298 0.3298
Brugia malayi 60S ribosomal protein L19 0.0024 0.003 0.0055
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0066 0.0229 0.0374
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0034 0.0077 0.0787
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.071 0.3298 0.3298
Brugia malayi larval opioid receptor 0.071 0.3298 0.6149
Loa Loa (eye worm) hypothetical protein 0.026 0.1155 0.2154
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0015 0.0028
Echinococcus granulosus rhodopsin orphan GPCR 0.071 0.3298 0.3298
Schistosoma mansoni opsin-like receptor 0.071 0.3298 0.3298
Echinococcus granulosus g protein coupled receptor 0.071 0.3298 0.3298
Brugia malayi putative neuropeptide receptor NPR1 0.071 0.3298 0.6149
Loa Loa (eye worm) glutathione reductase 0.0034 0.008 0.015
Schistosoma mansoni steroid hormone receptor ad4bp 0.0048 0.0143 0.0143
Loa Loa (eye worm) nuclear factor I 0.0023 0.0025 0.0047
Leishmania major 4-coumarate:coa ligase-like protein 0.0046 0.0136 0.0858
Toxoplasma gondii cytochrome p450 superfamily protein 0.0034 0.0077 0.0711
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0112 0.045 0.1313
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0145 0.0605 0.0605
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0049 0.0151 0.0951
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0158 0.0668 0.4216
Echinococcus multilocularis calpain family protein 1, d 0.0043 0.0119 0.0119
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0048 0.0143 0.0266
Plasmodium falciparum GAF domain-related protein, putative 0.0021 0.0015 0.0515
Loa Loa (eye worm) hypothetical protein 0.0297 0.1332 0.2484
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0002 0.0012
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0126 0.0517 1
Schistosoma mansoni neuropeptide F-like receptor 0.071 0.3298 0.3298
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0035 0.0083 0.0082
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0066 0.0229 0.1444
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0048 0.0143 0.0266
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0153 0.0646 0.1204
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0236 0.1479
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0066 0.0229 0.0374
Echinococcus multilocularis G protein coupled receptor 139 0.071 0.3298 0.3298
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0022 0.0023 0.0023
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0035 0.0058
Loa Loa (eye worm) hypothetical protein 0.0092 0.0353 0.0657
Echinococcus granulosus Nuclear hormone receptor HR96 0.0022 0.0023 0.0023
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0034 0.0077 0.0185
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0157 0.0982
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0043
Echinococcus granulosus neuropeptide receptor A26 0.1107 0.519 0.519
Leishmania major 4-coumarate:coa ligase-like protein 0.0046 0.0136 0.0858
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0034 0.0077 0.0787
Echinococcus granulosus L aminoadipate semialdehyde 0.0076 0.0277 0.0277
Brugia malayi hypothetical protein 0.0025 0.0036 0.0067
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0034 0.0076 0.2615
Brugia malayi Nuclear hormone receptor E75 0.0022 0.0023 0.0043
Mycobacterium leprae conserved hypothetical protein 0.0112 0.045 0.8666
Schistosoma mansoni jumonji/arid domain-containing protein 0.0067 0.0238 0.0237
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0102 0.0402 0.2539
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0043
Echinococcus granulosus single minded 2 0.0039 0.0101 0.0101
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0457 0.2094 0.3904
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0716 0.333 1
Schistosoma mansoni neuropeptide receptor 0.071 0.3298 0.3298
Schistosoma mansoni biogenic amine (dopamine) receptor 0.071 0.3298 0.3298
Schistosoma mansoni amine GPCR 0.071 0.3298 0.3298
Schistosoma mansoni smad1 5 8 and 0.0041 0.0114 0.0113
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0015 0.0096
Loa Loa (eye worm) intermediate filament protein 0.0114 0.0458 0.0854
Entamoeba histolytica phosphofructokinase, putative 0.0126 0.0517 0.6257
Echinococcus granulosus tar DNA binding protein 0.0197 0.0856 0.0856
Echinococcus multilocularis RUN 0.0022 0.0019 0.0019
Schistosoma mansoni zinc finger protein 0.0022 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0043
Toxoplasma gondii GAF domain-containing protein 0.0021 0.0015 0.014
Entamoeba histolytica hypothetical protein 0.0191 0.0827 1
Echinococcus granulosus tumor protein p63 0.2031 0.9591 0.9591
Mycobacterium ulcerans 6-phosphofructokinase 0.0126 0.0517 0.644
Trichomonas vaginalis set domain proteins, putative 0.1301 0.6114 1
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0112 0.045 0.5581
Brugia malayi ecdysteroid receptor 0.0048 0.0143 0.0266
Trypanosoma cruzi ISWI complex protein 0.0032 0.0067 0.0423
Plasmodium vivax 6-phosphofructokinase, putative 0.0034 0.0079 0.073
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0066 0.0229 0.213
Onchocerca volvulus Adenylate cyclase type 2 homolog 0.0083 0.0313 0.0511
Leishmania major importin beta-1 subunit, putative 0.0025 0.0035 0.0221
Echinococcus granulosus 7TM GPCR rhodopsin 0.071 0.3298 0.3298
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0191 0.0827 0.0827
Brugia malayi Serotonin receptor 0.071 0.3298 0.6149
Leishmania major cathepsin L-like protease 0.0067 0.0236 0.1489
Echinococcus multilocularis GPCR, family 2 0.0145 0.0605 0.0605
Schistosoma mansoni retinoic acid receptor RXR 0.0048 0.0143 0.0143
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0066 0.0229 0.0229
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0115 0.0465 0.293
Brugia malayi putative neuropeptide receptor 0.071 0.3298 0.6149
Mycobacterium ulcerans esterase/lipase LipP 0.0112 0.045 0.5581
Brugia malayi hypothetical protein 0.0022 0.0019 0.0036
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0123 0.0501 0.082
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0035 0.0058
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0079 0.0291 0.0832
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0015 0.014
Onchocerca volvulus 0.0022 0.0023 0.0038
Trypanosoma cruzi kinesin, putative 0.0018 0.0002 0.0012
Brugia malayi G protein-coupled receptor 0.071 0.3298 0.6149
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0061 0.0205 0.0205
Echinococcus granulosus mothers against decapentaplegic 5 0.0041 0.0114 0.0113
Mycobacterium ulcerans hypothetical protein 0.0112 0.045 0.5581
Brugia malayi Isocitrate dehydrogenase 0.0035 0.0083 0.0154
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0018 0.0002 0.0012
Leishmania major trypanothione reductase 0.0034 0.008 0.0507
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.0084
Loa Loa (eye worm) DR-78 0.0022 0.0023 0.0043
Schistosoma mansoni peptide (allatostatin)-like receptor 0.071 0.3298 0.3298
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0034 0.0077 0.0787
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0145 0.0605 0.0605
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0043
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0066 0.0229 0.213
Echinococcus granulosus rhodopsin orphan GPCR 0.071 0.3298 0.3298
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0023 0.0024 0.0224
Schistosoma mansoni hypothetical protein 0.0032 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Schistosoma mansoni hypothetical protein 0.1106 0.5185 0.5185
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0046 0.0136 0.2408
Loa Loa (eye worm) MH1 domain-containing protein 0.0019 0.0004 0.0008
Brugia malayi calpain family protein 1 0.0061 0.0205 0.0381
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0018 0.0002 0.0012
Echinococcus multilocularis fmrfamide receptor 0.071 0.3298 0.3298
Schistosoma mansoni Smad4 0.0019 0.0004 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0236 0.1479
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0048 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.0147 0.0614 0.1146
Schistosoma mansoni nuclear receptor nhr-48 0.0022 0.0023 0.0023
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0048 0.0143 0.0143
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.0084
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0034 0.0077 0.0185
Brugia malayi G-protein coupled receptor 0.071 0.3298 0.6149
Schistosoma mansoni polycystin 1-related 0.0022 0.0019 0.0019
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.071 0.3298 0.3298
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0048 0.0143 0.0266
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0034 0.0077 0.0185
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0066 0.0229 0.213
Echinococcus granulosus somatostatin receptor 0.071 0.3298 0.3298
Echinococcus granulosus adenylate cyclase 9 0.0083 0.0313 0.0313
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0048 0.0143 0.0266
Echinococcus granulosus GTP binding nuclear protein Ran 0.0023 0.0024 0.0024
Schistosoma mansoni lipoxygenase 0.0022 0.0019 0.0019
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0034 0.0076 0.0185
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0066 0.0229 0.213
Loa Loa (eye worm) nuclear receptor NHR-67 0.0022 0.0023 0.0043
Echinococcus granulosus g protein coupled receptor 0.071 0.3298 0.3298
Brugia malayi Serotonin receptor 0.071 0.3298 0.6149
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0066 0.0229 0.1434
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0034 0.0081 1
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0066 0.0229 0.7858
Plasmodium falciparum phosphodiesterase delta, putative 0.0066 0.0229 0.7858
Trypanosoma cruzi hypothetical protein, conserved 0.0066 0.0229 0.1444
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0035 0.0082 0.0852
Echinococcus granulosus dro:myosuppressin receptor 0.071 0.3298 0.3298
Echinococcus multilocularis lamin dm0 0.0114 0.0458 0.0458
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0022 0.0023 0.0043
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0126 0.0517 1
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0024 0.0024
Loa Loa (eye worm) G-protein coupled receptor 0.071 0.3298 0.6149
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0048 0.0143 0.0266
Trypanosoma brucei hypothetical protein, conserved 0.0066 0.0229 0.1434
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0034 0.0076 0.0469
Loa Loa (eye worm) jmjC domain-containing protein 0.0067 0.0238 0.0443
Loa Loa (eye worm) hypothetical protein 0.0086 0.0328 0.0611
Brugia malayi MH1 domain containing protein 0.0023 0.0025 0.0047
Brugia malayi Thioredoxin reductase 0.0034 0.008 0.015
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.071 0.3298 0.3298
Mycobacterium tuberculosis Conserved protein 0.0112 0.045 0.1313
Echinococcus granulosus nuclear factor of activated T cells 5 0.0086 0.0324 0.0323
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Echinococcus granulosus geminin 0.0452 0.2068 0.2068
Toxoplasma gondii isocitrate dehydrogenase 0.0035 0.0083 0.0767
Echinococcus multilocularis hypothetical protein 0.0018 0.0002 0.0002
Loa Loa (eye worm) RNA binding protein 0.0197 0.0856 0.1596
Brugia malayi jmjC domain containing protein 0.0067 0.0238 0.0443
Loa Loa (eye worm) hypothetical protein 0.0145 0.0605 0.1128
Schistosoma mansoni amine GPCR 0.071 0.3298 0.3298
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0025 0.0037 0.0037
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0243 0.1074 0.1074
Leishmania major hypothetical protein, conserved 0.0051 0.0157 0.0993
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0115 0.0465 0.2922
Echinococcus granulosus rhodopsin orphan GPCR 0.071 0.3298 0.3298
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0079 0.0129
Loa Loa (eye worm) hypothetical protein 0.0066 0.0229 0.0427
Echinococcus granulosus Nuclear hormone receptor HR96 0.0022 0.0023 0.0023
Trichomonas vaginalis CMGC family protein kinase 0.0115 0.0465 0.076
Entamoeba histolytica hypothetical protein 0.0025 0.0035 0.0423
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0022 0.0023 0.0023
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0002 0.0012
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0023 0.0024 0.0045
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0201 0.0873 0.0873
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0123 0.0501 0.0501
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0048 0.0143 0.0233
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0066 0.0229 0.0427
Brugia malayi hypothetical protein 0.0025 0.0036 0.0067
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Schistosoma mansoni neuropeptide receptor 0.071 0.3298 0.3298
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0019 0.0004 0.0007
Echinococcus granulosus calpain 5 0.0018 0.0002 0.0002
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.071 0.3298 0.3298
Loa Loa (eye worm) hypothetical protein 0.0048 0.0143 0.0266
Schistosoma mansoni hypothetical protein 0.071 0.3298 0.3298
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0035 0.0083 0.0082
Loa Loa (eye worm) beta-lactamase 0.0112 0.045 0.084
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0115 0.0465 0.4323
Echinococcus granulosus beta LACTamase domain containing family member 0.0112 0.045 0.045
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0123 0.0501 0.082
Echinococcus multilocularis calpain 7 (C02 family) 0.0018 0.0002 0.0002
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.063 0.2919 0.2919
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0229 0.0374
Echinococcus multilocularis cpg binding protein 0.0086 0.0326 0.0326
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0035 0.0082 0.0503
Brugia malayi hypothetical protein 0.071 0.3298 0.6149
Onchocerca volvulus 0.071 0.3298 0.5393
Loa Loa (eye worm) hypothetical protein 0.0034 0.0081 0.015
Brugia malayi nuclear receptor RXR 0.0022 0.0023 0.0043
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0048 0.0143 0.0266
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0048 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.0457 0.2094 0.3904
Echinococcus granulosus cytochrome P450 2K1 0.0034 0.0077 0.0076
Trypanosoma cruzi major cysteine proteinase, putative 0.0053 0.0168 0.1057
Brugia malayi Nuclear hormone receptor-like 1 0.0048 0.0143 0.0266
Loa Loa (eye worm) TYRA-2 protein 0.071 0.3298 0.6149
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0079 0.0291 0.5488
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0025 0.0036 0.0036
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0034 0.0077 0.0482
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0197 0.0856 0.1596
Trichomonas vaginalis CMGC family protein kinase 0.0115 0.0465 0.076
Brugia malayi Nuclear hormone receptor-like 1 0.0025 0.0036 0.0067
Brugia malayi Bromodomain containing protein 0.0087 0.0328 0.0612
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0034 0.0077 0.047
Brugia malayi bHLH-PAS transcription factor 0.0039 0.0101 0.0188
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0034 0.0076 0.0784
Echinococcus multilocularis muscleblind protein 1 0.0398 0.1813 0.1813
Onchocerca volvulus 0.071 0.3298 0.5393
Brugia malayi beta-lactamase 0.0112 0.045 0.084
Echinococcus multilocularis L aminoadipate semialdehyde 0.0076 0.0277 0.0277
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0051 0.016 0.016
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0091 0.0349 0.0571
Trichomonas vaginalis esterase, putative 0.0112 0.045 0.0737
Echinococcus multilocularis serotonin receptor 0.071 0.3298 0.3298
Brugia malayi calpain 5 0.0018 0.0002 0.0003
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0048 0.0143 0.0143
Onchocerca volvulus Adenylate cyclase type 3 homolog 0.0083 0.0313 0.0511
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0153 0.0646 0.0646
Echinococcus granulosus orexin receptor type 2 0.071 0.3298 0.3298
Leishmania major hypothetical protein, conserved 0.0112 0.045 0.2842
Brugia malayi MH1 domain containing protein 0.0041 0.0114 0.0211
Brugia malayi Nuclear hormone receptor E75 0.0022 0.0023 0.0043
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0034 0.0077 0.0185
Schistosoma mansoni hypothetical protein 0.0043 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Mycobacterium tuberculosis Probable oxidoreductase 0.0087 0.0333 0.0958
Plasmodium vivax phosphodiesterase gamma, putative 0.0066 0.0229 0.213
Onchocerca volvulus 0.0076 0.0277 0.0453
Trichomonas vaginalis CMGC family protein kinase 0.0115 0.0465 0.076
Schistosoma mansoni rhodopsin-like orphan GPCR 0.071 0.3298 0.3298
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0034 0.0076 0.048
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0074 0.0271 0.0271
Trichomonas vaginalis ap endonuclease, putative 0.0034 0.0076 0.0125
Leishmania major hypothetical protein, conserved 0.0066 0.0229 0.1444
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0158 0.0668 0.0668
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0034 0.0076 0.0709
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0061 0.0205 0.0205
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0236 0.1479
Loa Loa (eye worm) latrophilin receptor protein 2 0.0145 0.0605 0.1128
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0166 0.0706 0.4454
Brugia malayi follicle stimulating hormone receptor 0.0958 0.4479 0.8353
Echinococcus granulosus ecdysone induced protein 78C 0.0048 0.0143 0.0143
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0091 0.0349 0.3245
Schistosoma mansoni methyl-cpg binding protein mbd 0.0035 0.0085 0.0084
Entamoeba histolytica deoxycytidyl transferase, putative 0.0021 0.0015 0.0183
Loa Loa (eye worm) neuropeptide F receptor 0.071 0.3298 0.6149
Brugia malayi hypothetical protein 0.0022 0.0023 0.0043
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0022 0.0023 0.0023
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0123 0.0501 0.082
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0123 0.0501 0.082
Schistosoma mansoni hypothetical protein 0.0034 0.0077 0.0076
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0046 0.0136 0.1551
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0048 0.0143 0.0266
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0064 0.0219 0.0219
Schistosoma mansoni hypothetical protein 0.0145 0.0605 0.0605
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0066 0.0229 0.0229
Plasmodium vivax acyl-CoA synthetase, putative 0.0034 0.0081 0.0748
Schistosoma mansoni smad 0.0041 0.0114 0.0113
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0112 0.045 0.084
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0157 0.1464
Echinococcus granulosus dna polymerase kappa 0.0021 0.0015 0.0015
Entamoeba histolytica phosphofructokinase, putative 0.0126 0.0517 0.6257
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0958 0.4479 0.8353
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0034 0.0077 0.0787
Schistosoma mansoni cpg binding protein 0.0086 0.0326 0.0326
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0066 0.0229 0.7858
Brugia malayi mothers against decapentaplegic homolog 3 0.0019 0.0004 0.0008
Echinococcus multilocularis rhodopsin orphan GPCR 0.071 0.3298 0.3298
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0034 0.0077 0.0787
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0034 0.0079 0.1409
Leishmania major DNA polymerase eta, putative 0.0021 0.0015 0.0096
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0034 0.0081 0.0838
Echinococcus multilocularis muscleblind protein 0.0398 0.1813 0.1813
Mycobacterium tuberculosis Probable hydrolase 0.0112 0.045 0.1313
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0066 0.0229 0.0229
Trypanosoma cruzi DNA polymerase eta, putative 0.0021 0.0015 0.0096
Echinococcus granulosus mitogen activated protein kinase 3 0.0115 0.0465 0.0464
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0153 0.0646 0.0646
Trichomonas vaginalis phosphofructokinase, putative 0.0126 0.0517 0.0846
Loa Loa (eye worm) TAR-binding protein 0.0197 0.0856 0.1596
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.071 0.3298 0.3298
Echinococcus multilocularis nuclear receptor nhr 48 0.0022 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Brugia malayi Smad1 0.0041 0.0114 0.0211
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0123 0.0501 0.082
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0035 0.0083 0.0203
Schistosoma mansoni bromodomain containing protein 0.0143 0.0596 0.0596
Brugia malayi G protein-coupled receptor F59B2.13 0.071 0.3298 0.6149
Echinococcus granulosus rhodopsin orphan GPCR 0.071 0.3298 0.3298
Brugia malayi AKH receptor 0.071 0.3298 0.6149
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0153 0.0646 0.0646
Plasmodium vivax calpain, putative 0.0018 0.0002 0.0017
Loa Loa (eye worm) CXXC zinc finger family protein 0.0078 0.0286 0.0533
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.063 0.2919 0.5444
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0043
Leishmania major cAMP-specific phosphodiesterase, putative 0.0066 0.0229 0.1444
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0018 0.0002 0.0012
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0063 0.0385
Trypanosoma cruzi cruzipain precursor, putative 0.0067 0.0236 0.1489
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.0084
Brugia malayi hypothetical protein 0.071 0.3298 0.6149
Trypanosoma brucei 60S ribosomal protein L19, putative 0.0024 0.003 0.0176
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0079 0.0129
Loa Loa (eye worm) hypothetical protein 0.0112 0.0448 0.0836
Toxoplasma gondii exonuclease III APE 0.0034 0.0076 0.0709
Brugia malayi hypothetical protein 0.0022 0.0019 0.0036
Loa Loa (eye worm) steroid hormone receptor 0.0048 0.0143 0.0266
Echinococcus multilocularis survival motor neuron protein 1 0.0435 0.1989 0.1989
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.071 0.3298 0.3298
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0048 0.0143 0.0266
Leishmania major mitochondrial DNA polymerase beta 0.035 0.1585 1
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0123 0.0501 0.082
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0043
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0034 0.0079 0.9699
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0153 0.0646 0.0646
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0028
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0066 0.0229 0.213
Schistosoma mansoni amine GPCR 0.071 0.3298 0.3298
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0034 0.0077 0.0787
Entamoeba histolytica acyl-CoA synthetase, putative 0.0046 0.0136 0.1644
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0066 0.0229 0.213
Entamoeba histolytica hypothetical protein 0.0191 0.0827 1
Trypanosoma cruzi 60S ribosomal protein L19, putative 0.0024 0.003 0.0188
Mycobacterium ulcerans aldehyde dehydrogenase 0.0158 0.0668 0.8374
Mycobacterium ulcerans aldehyde dehydrogenase 0.0158 0.0668 0.8374
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0079 0.0291 0.0832
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0158 0.0668 0.0668
Brugia malayi MH1 domain containing protein 0.0041 0.0114 0.0211
Trypanosoma cruzi hypothetical protein, conserved 0.0066 0.0229 0.1444
Echinococcus multilocularis zinc finger protein 0.0052 0.0165 0.0165
Trichomonas vaginalis phosphofructokinase, putative 0.0126 0.0517 0.0846
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.071 0.3298 0.6149
Leishmania major 60S ribosomal protein L19, putative 0.0024 0.003 0.0188
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0086 0.0328 0.0536
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0229 0.0374
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0201 0.0873 0.0873
Echinococcus granulosus serotonin receptor 0.071 0.3298 0.3298
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0048 0.0143 0.0143
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0079 0.0129
Leishmania major 4-coumarate:coa ligase-like protein 0.0046 0.0136 0.0858
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0145 0.0605 0.1128
Echinococcus granulosus rhodopsin orphan GPCR 0.071 0.3298 0.3298
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0102 0.0402 0.0658
Brugia malayi RNA binding protein 0.0197 0.0856 0.1596
Onchocerca volvulus 0.0112 0.045 0.0736
Loa Loa (eye worm) hypothetical protein 0.0025 0.0036 0.0067
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0079 0.0129
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0066 0.0229 0.0229
Loa Loa (eye worm) melatonin receptor type 1A 0.071 0.3298 0.6149
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0066 0.0229 0.0374
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0123 0.0501 0.082
Echinococcus granulosus thyroid hormone receptor alpha 0.0022 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0046 0.0136 0.0254
Brugia malayi hypothetical protein 0.071 0.3298 0.6149
Loa Loa (eye worm) hypothetical protein 0.0034 0.0081 0.015
Loa Loa (eye worm) MH1 domain-containing protein 0.0041 0.0114 0.0211
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.071 0.3298 0.3298
Loa Loa (eye worm) neuropeptide F receptor 0.071 0.3298 0.6149
Echinococcus granulosus smad 0.0041 0.0114 0.0113
Schistosoma mansoni smad 0.0019 0.0004 0.0004
Echinococcus granulosus Smad4 0.0041 0.0114 0.0113
Loa Loa (eye worm) hypothetical protein 0.0025 0.0036 0.0067
Schistosoma mansoni nuclear hormone receptor 0.0048 0.0143 0.0143
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0087 0.0333 0.0958
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0.0019 0.0019
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0035 0.0083 0.2828
Schistosoma mansoni hypothetical protein 0.071 0.3298 0.3298
Echinococcus granulosus cpg binding protein 0.0086 0.0326 0.0326
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.071 0.3298 0.6149
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0048 0.0143 0.0143
Schistosoma mansoni Smad4 0.0019 0.0004 0.0004
Echinococcus granulosus histone acetyltransferase KAT2B 0.0091 0.0349 0.0349
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0035 0.0083 0.0767
Echinococcus granulosus Solute carrier family 22 5 0.1087 0.5095 0.5095
Trypanosoma brucei trypanothione reductase 0.0034 0.008 0.0495
Leishmania major hypothetical protein, conserved 0.0032 0.0067 0.0423
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0046 0.0136 0.2408
Echinococcus multilocularis neuropeptide Y receptor 0.071 0.3298 0.3298
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0072 0.017
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0086 0.0328 0.0611
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0066 0.0229 0.213
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0112 0.045 0.045
Echinococcus multilocularis snurportin 1 0.0329 0.1483 0.1483
Trypanosoma brucei cytochrome P450, putative 0.0051 0.0159 0.0995
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0034 0.0077 0.0185
Brugia malayi sulfakinin receptor protein 0.071 0.3298 0.6149
Leishmania major cytochrome p450-like protein 0.0051 0.0159 0.1005
Loa Loa (eye worm) hypothetical protein 0.0312 0.1405 0.2619
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0034 0.0076 0.0921
Onchocerca volvulus 0.071 0.3298 0.5393
Schistosoma mansoni tar DNA-binding protein 0.0197 0.0856 0.0856
Plasmodium vivax 60S ribosomal protein L19, putative 0.0024 0.003 0.0277
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0115 0.0465 0.0866
Brugia malayi 6-phosphofructokinase 0.0126 0.0517 0.0965
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0066 0.0229 0.0427
Trypanosoma brucei mitochondrial DNA polymerase beta 0.035 0.1585 1
Toxoplasma gondii hypothetical protein 0.0056 0.0185 0.1724
Schistosoma mansoni ap endonuclease 0.0034 0.0076 0.0076
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0018 0.0002 0.0012
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0034 0.0077 0.0482
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0066 0.0229 0.213
Echinococcus granulosus neuropeptide Y receptor 0.071 0.3298 0.3298
Brugia malayi RNA recognition motif domain containing protein 0.0197 0.0856 0.1596
Entamoeba histolytica phosphofructokinase, putative 0.0126 0.0517 0.6257
Schistosoma mansoni hypothetical protein 0.0145 0.0605 0.0605
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0066 0.0229 0.0229
Onchocerca volvulus 0.0024 0.003 0.0048
Loa Loa (eye worm) hypothetical protein 0.0053 0.0168 0.0313
Brugia malayi MH2 domain containing protein 0.0608 0.2812 0.5245
Brugia malayi MH2 domain containing protein 0.0041 0.0114 0.0211
Echinococcus multilocularis ribosomal protein L19 0.0024 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0048 0.0143 0.0266
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0124 0.0506 0.0505
Schistosoma mansoni calpain-7 (C02 family) 0.0024 0.0031 0.0031
Mycobacterium leprae conserved hypothetical protein 0.0021 0.0018 0.0051
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0043
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0048 0.0143 0.0266
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0035 0.0083 0.0508
Echinococcus granulosus G protein coupled receptor 139 0.071 0.3298 0.3298
Mycobacterium ulcerans putative regulatory protein 0.0039 0.0101 0.1102
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0123 0.0501 0.3163
Brugia malayi Dopamine receptor protein 2 0.071 0.3298 0.6149
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0015 0.0084
Echinococcus granulosus dna polymerase eta 0.0021 0.0015 0.0015
Echinococcus granulosus fetal alzheimer antigen falz 0.0051 0.016 0.016
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0089 0.0339 0.0632
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0066 0.0229 0.213
Echinococcus multilocularis smad 0.0041 0.0114 0.0113
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.071 0.3298 0.5393
Plasmodium vivax importin-beta 2, putative 0.0031 0.0063 0.0584
Onchocerca volvulus 0.071 0.3298 0.5393
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.071 0.3298 0.3298
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0074 0.0271 0.0271
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0034 0.0077 0.0482
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0048 0.0143 0.0143
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0021 0.0018 0.0163
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.071 0.3298 0.3298
Mycobacterium tuberculosis Probable dehydrogenase 0.0079 0.0291 0.0832
Schistosoma mansoni zinc finger protein 0.0032 0.0067 0.0067
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0034 0.0077 0.0185
Echinococcus granulosus FTZ F1 alpha 0.0048 0.0143 0.0143
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0064 0.0219 0.0219
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0035 0.0082 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0002 0.0012
Onchocerca volvulus Neuropeptide F receptor homolog 0.071 0.3298 0.5393
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0066 0.0229 0.0229
Echinococcus multilocularis neuropeptide receptor A26 0.1107 0.519 0.519
Brugia malayi hypothetical protein 0.071 0.3298 0.6149
Schistosoma mansoni biogenic amine (dopamine) receptor 0.071 0.3298 0.3298
Echinococcus multilocularis dnaJ subfamily B 0.1106 0.5185 0.5185
Loa Loa (eye worm) hypothetical protein 0.0031 0.0063 0.0117
Onchocerca volvulus 0.071 0.3298 0.5393
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0034 0.0077 0.0787
Loa Loa (eye worm) hypothetical protein 0.0435 0.1989 0.371
Schistosoma mansoni thyroid hormone receptor 0.0171 0.0732 0.0732
Schistosoma mansoni tar DNA-binding protein 0.0197 0.0856 0.0856
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0019 0.0019
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.071 0.3298 0.3298
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0034 0.0077 0.0787
Trichomonas vaginalis D-aminoacylase, putative 0.0112 0.045 0.0737
Brugia malayi hypothetical protein 0.0141 0.059 0.1099
Toxoplasma gondii hypothetical protein 0.0021 0.0015 0.014
Schistosoma mansoni hypothetical protein 0.071 0.3298 0.3298
Brugia malayi Dopamine receptor protein 1 0.071 0.3298 0.6149
Echinococcus multilocularis thyroid hormone receptor alpha 0.0171 0.0732 0.0732
Schistosoma mansoni ran 0.0023 0.0024 0.0024
Trichomonas vaginalis ran, putative 0.0023 0.0024 0.004
Loa Loa (eye worm) PDE1B protein 0.063 0.2919 0.5444
Loa Loa (eye worm) hypothetical protein 0.0398 0.1813 0.338
Schistosoma mansoni jumonji/arid domain-containing protein 0.0067 0.0238 0.0237
Brugia malayi Steroid receptor seven-up type 2 0.0142 0.0592 0.1105
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0015 0.0002
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.071 0.3298 0.6149
Echinococcus multilocularis neuropeptide Y receptor 0.071 0.3298 0.3298
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0191 0.0827 0.0827
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0157 0.5403
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0236 0.1479
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0236 0.1479
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0015 0.0084
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0123 0.0501 0.082
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.071 0.3298 0.3298
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0123 0.0501 0.0501
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0243 0.1074 1
Brugia malayi neuropeptide F receptor 0.071 0.3298 0.6149
Brugia malayi hypothetical protein 0.071 0.3298 0.6149
Echinococcus granulosus g-protein coupled receptor 0.071 0.3298 0.3298
Toxoplasma gondii hypothetical protein 0.0057 0.0189 0.1755
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0034 0.0079 0.073
Echinococcus granulosus tm gpcr rhodopsin 0.071 0.3298 0.3298
Echinococcus granulosus lamin dm0 0.0114 0.0458 0.0458
Brugia malayi Cytochrome P450 family protein 0.0051 0.0159 0.0297
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0046 0.0136 0.1551
Schistosoma mansoni aryl hydrocarbon receptor 0.0052 0.0166 0.0166
Loa Loa (eye worm) hypothetical protein 0.0023 0.0025 0.0047
Brugia malayi isocitrate dehydrogenase 0.0035 0.0083 0.0154
Schistosoma mansoni aldehyde dehydrogenase 0.0158 0.0668 0.0668
Trypanosoma cruzi hypothetical protein, conserved 0.0066 0.0229 0.1444
Brugia malayi Pre-SET motif family protein 0.0165 0.0704 0.1313
Schistosoma mansoni 60S ribosomal protein L19 0.0024 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0102 0.0402 0.0658
Echinococcus multilocularis Smad4 0.0041 0.0114 0.0113
Loa Loa (eye worm) cytochrome P450 family protein 0.0051 0.0159 0.0297
Echinococcus multilocularis dro:myosuppressin receptor 0.071 0.3298 0.3298
Schistosoma mansoni intermediate filament proteins 0.0114 0.0458 0.0458
Trichomonas vaginalis penicillin-binding protein, putative 0.0112 0.045 0.0737
Echinococcus multilocularis ecdysone induced protein 78C 0.0048 0.0143 0.0143
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0236 0.1479
Schistosoma mansoni tar DNA-binding protein 0.0197 0.0856 0.0856
Entamoeba histolytica hypothetical protein 0.0191 0.0827 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0066 0.0229 0.213
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.003 0.0059 0.0059
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0457 0.2094 0.3904
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0165 0.0704 0.0704
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0021 0.0018 0.0163
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0136 0.0254
Loa Loa (eye worm) hypothetical protein 0.0034 0.0081 0.015
Loa Loa (eye worm) CYP4Cod1 0.0051 0.0159 0.0297
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0046 0.0136 0.0365
Mycobacterium tuberculosis Probable esterase LipL 0.0112 0.045 0.1313
Schistosoma mansoni Smad4 0.0041 0.0114 0.0113
Loa Loa (eye worm) Smad1 0.0041 0.0114 0.0211
Brugia malayi orphan nuclear receptor NR2E1 0.0022 0.0023 0.0043
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0021 0.0018 0.0033
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0066 0.0229 0.0229
Brugia malayi exodeoxyribonuclease III family protein 0.0034 0.0076 0.0142
Echinococcus granulosus RUN 0.0022 0.0019 0.0019
Echinococcus multilocularis fmrfamide receptor 0.071 0.3298 0.3298
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0048 0.0143 0.0266
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0049 0.0151 0.0951
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0043
Loa Loa (eye worm) acetyltransferase 0.0297 0.1331 0.2482
Brugia malayi CXXC zinc finger family protein 0.0078 0.0286 0.0533
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0066 0.0229 0.213
Echinococcus multilocularis alpha 1A adrenergic receptor 0.071 0.3298 0.3298
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0034 0.0077 0.0185
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0157 0.0993
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.1219 0.5726 0.5726
Schistosoma mansoni hypothetical protein 0.0022 0.0019 0.0019
Trichomonas vaginalis D-aminoacylase, putative 0.0112 0.045 0.0737
Schistosoma mansoni RAR-like nuclear receptor 0.0048 0.0143 0.0143
Brugia malayi Tachykinin-like peptides receptor 99D 0.071 0.3298 0.6149
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0046 0.0136 0.1551
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Schistosoma mansoni myosin xvIII 0.071 0.3298 0.3298
Echinococcus granulosus calpain A 0.0018 0.0002 0.0002
Schistosoma mansoni nuclear receptor 0.0022 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0112 0.045 0.084
Echinococcus multilocularis isocitrate dehydrogenase 0.0035 0.0083 0.0082
Trypanosoma brucei unspecified product 0.0021 0.0015 0.0084
Brugia malayi PAS domain containing protein 0.0052 0.0166 0.0309
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0165 0.0704 0.0704
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0021 0.0018 0.0603
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0066 0.0229 0.4756
Onchocerca volvulus 0.0165 0.0704 0.1152
Echinococcus granulosus hypothetical protein 0.071 0.3298 0.3298
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0034 0.0079 0.2695
Brugia malayi G-protein coupled receptor 0.071 0.3298 0.6149
Echinococcus granulosus zinc finger protein 0.0052 0.0165 0.0165
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0025 0.0036 0.0036
Loa Loa (eye worm) MH2 domain-containing protein 0.0608 0.2812 0.5245
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0048 0.0143 0.0143
Schistosoma mansoni methyl-cpg binding protein mbd 0.0035 0.0085 0.0084
Brugia malayi tailless protein 0.0022 0.0023 0.0043
Echinococcus multilocularis neuropeptide FF receptor 2 0.071 0.3298 0.3298
Onchocerca volvulus 0.0112 0.045 0.0736
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0048 0.0143 0.0143
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.1219 0.5726 0.5726
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0034 0.0077 0.0787
Schistosoma mansoni ap endonuclease 0.0034 0.0076 0.0076
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0048 0.0143 0.0143
Schistosoma mansoni neuropeptide receptor 0.071 0.3298 0.3298
Schistosoma mansoni rhodopsin-like orphan GPCR 0.071 0.3298 0.3298
Trichomonas vaginalis ap endonuclease, putative 0.0034 0.0076 0.0125
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0123 0.0501 0.3155
Leishmania major GTP-binding protein, putative 0.0023 0.0024 0.0152
Loa Loa (eye worm) hypoxia-induced factor 1 0.0162 0.069 0.1286
Schistosoma mansoni histamine h1 receptor 0.071 0.3298 0.3298
Brugia malayi Serotonin/octopamine receptor family protein 7 0.071 0.3298 0.6149
Echinococcus multilocularis geminin 0.0452 0.2068 0.2068
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0079 0.0129
Loa Loa (eye worm) hypothetical protein 0.0055 0.0178 0.0331
Brugia malayi Muscleblind-like protein 0.0398 0.1813 0.338
Echinococcus multilocularis g protein coupled receptor 0.071 0.3298 0.3298
Loa Loa (eye worm) hypothetical protein 0.0112 0.045 0.084
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0066 0.0229 0.1434
Echinococcus granulosus fmrfamide receptor 0.071 0.3298 0.3298
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0043
Schistosoma mansoni hypothetical protein 0.0023 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0114 0.0458 0.0854
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Plasmodium vivax multidomain scavenger receptor, putative 0.0022 0.0019 0.0178
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0063 0.0385
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0021 0.0018 0.0033
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0123 0.0501 0.082
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Trypanosoma cruzi hypothetical protein, conserved 0.0066 0.0229 0.1444
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0035 0.0082 0.0133
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0329 0.1483 0.2765
Echinococcus granulosus rhodopsin orphan GPCR 0.071 0.3298 0.3298
Echinococcus granulosus mothers against decapentaplegic 2 0.0019 0.0004 0.0004
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0157 0.5403
Plasmodium falciparum LCCL domain-containing protein 0.0022 0.0019 0.0657
Echinococcus granulosus mixed lineage leukemia protein mll 0.0025 0.0037 0.0037
Brugia malayi nuclear hormone receptor 0.0022 0.0023 0.0043
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0034 0.0077 0.0185
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.0084
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0034 0.008 0.0197
Echinococcus multilocularis rhodopsin orphan GPCR 0.071 0.3298 0.3298
Plasmodium falciparum acyl-CoA synthetase 0.0034 0.0081 0.276
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0066 0.0229 0.7858
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0066 0.0229 0.0229
Toxoplasma gondii 6-phosphofructokinase 0.0034 0.0079 0.073
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0015 0.0096
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Schistosoma mansoni biogenic amine receptor 0.071 0.3298 0.3298
Brugia malayi F/Y-rich N-terminus family protein 0.0034 0.0077 0.0143
Schistosoma mansoni opsin-like receptor 0.071 0.3298 0.3298
Echinococcus multilocularis adenylate cyclase 9 0.0083 0.0313 0.0313
Onchocerca volvulus 0.071 0.3298 0.5393
Mycobacterium tuberculosis Conserved protein 0.0112 0.045 0.1313
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0035 0.0083 0.0082
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.071 0.3298 0.3298
Onchocerca volvulus 0.008 0.0296 0.0484
Brugia malayi acetyltransferase, GNAT family protein 0.0297 0.1331 0.2482
Plasmodium falciparum thioredoxin reductase 0.0034 0.008 0.2757
Trypanosoma cruzi hypothetical protein, conserved 0.0066 0.0229 0.1444
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0024 0.0024
Echinococcus multilocularis FTZ F1 alpha 0.0048 0.0143 0.0143
Schistosoma mansoni alpha-1 adrenergic receptor 0.071 0.3298 0.3298
Brugia malayi hypothetical protein 0.071 0.3298 0.6149
Brugia malayi nuclear hormone receptor 0.0048 0.0143 0.0266
Schistosoma mansoni tar DNA-binding protein 0.0197 0.0856 0.0856
Onchocerca volvulus 0.071 0.3298 0.5393
Schistosoma mansoni neuropeptide f receptor 76f 0.071 0.3298 0.3298
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0061 0.0207 0.0385
Brugia malayi hypothetical protein 0.0191 0.0827 0.1542
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.035 0.1585 1
Loa Loa (eye worm) bromodomain containing protein 0.0044 0.0125 0.0232
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.071 0.3298 0.3298
Echinococcus multilocularis neuropeptide receptor 0.071 0.3298 0.3298
Entamoeba histolytica Ran family GTPase 0.0023 0.0024 0.0291
Echinococcus granulosus 6 phosphofructokinase 0.0126 0.0517 0.0517
Echinococcus granulosus lysine specific demethylase 5A 0.0067 0.0238 0.0237
Plasmodium vivax SET domain containing protein 0.002 0.001 0.0096
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0034 0.0076 0.1358
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0066 0.0229 0.0374
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0035 0.0058
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0025 0.0036 0.0036
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0171 0.073 0.0729
Brugia malayi Cytochrome P450 family protein 0.0034 0.0077 0.0142
Mycobacterium leprae Conserved hypothetical protein 0.0034 0.0077 0.1221
Toxoplasma gondii thioredoxin reductase 0.0034 0.008 0.0747
Toxoplasma gondii hypothetical protein 0.0021 0.0015 0.014
Mycobacterium ulcerans lipase LipD 0.0112 0.045 0.5581
Echinococcus multilocularis 6 phosphofructokinase 0.0126 0.0517 0.0517
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0018 0.0002 0.0012
Trypanosoma cruzi cysteine peptidase, putative 0.0067 0.0236 0.1489
Schistosoma mansoni thyroid hormone receptor 0.0171 0.0732 0.0732
Brugia malayi intermediate filament protein 0.0114 0.0458 0.0854
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Echinococcus multilocularis lamin 0.0114 0.0458 0.0458
Trichomonas vaginalis inositol monophosphatase, putative 0.0035 0.0082 0.0133
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Echinococcus multilocularis mitogen activated protein kinase 0.0115 0.0465 0.0464
Onchocerca volvulus 0.071 0.3298 0.5393
Loa Loa (eye worm) hypothetical protein 0.0048 0.0143 0.0266
Echinococcus multilocularis importin subunit beta 1 0.0031 0.0063 0.0063
Echinococcus multilocularis tumor protein p63 0.2031 0.9591 0.9591
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0015 0.0015
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0123 0.0501 0.082
Schistosoma mansoni lamin 0.0114 0.0458 0.0458
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0002 0.0012
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0015 0.0002
Trichomonas vaginalis phosphofructokinase, putative 0.0126 0.0517 0.0846
Toxoplasma gondii histone lysine methyltransferase SET1 0.0165 0.0703 0.6544
Giardia lamblia Kinase, CMGC MAPK 0.0115 0.0465 1
Echinococcus granulosus neuropeptides capa receptor 0.071 0.3298 0.3298
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0048 0.0143 0.0143
Brugia malayi Cytochrome P450 family protein 0.0051 0.0159 0.0297
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0114 0.0458 0.0854
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0066 0.0229 0.0229
Trypanosoma cruzi ISWI complex protein 0.0032 0.0067 0.0423
Leishmania major hypothetical protein, conserved 0.0066 0.0229 0.1444
Loa Loa (eye worm) hypothetical protein 0.0046 0.0136 0.0254
Loa Loa (eye worm) hypothetical protein 0.0022 0.0023 0.0043
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0066 0.0229 0.0229
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.071 0.3298 0.6149
Echinococcus multilocularis mothers against decapentaplegic 6 0.0019 0.0004 0.0004
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0015 0.0015
Echinococcus granulosus neuropeptides capa receptor 0.071 0.3298 0.3298
Schistosoma mansoni hypothetical protein 0.0124 0.0506 0.0505
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0034 0.0079 0.1219
Loa Loa (eye worm) hypothetical protein 0.0398 0.1813 0.338
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0115 0.0465 0.293
Entamoeba histolytica hypothetical protein 0.0191 0.0827 1
Brugia malayi hypoxia-induced factor 1 0.0162 0.069 0.1286
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0059 0.0198 0.0197
Trypanosoma cruzi 60S ribosomal protein L19, putative 0.0024 0.003 0.0188
Trichomonas vaginalis 60S ribosomal protein L19, putative 0.0024 0.003 0.0049
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0015 0.0028
Loa Loa (eye worm) hypothetical protein 0.0048 0.0143 0.0266
Onchocerca volvulus 0.0112 0.045 0.0736
Loa Loa (eye worm) hypothetical protein 0.002 0.0014 0.0025
Brugia malayi latrophilin 2 splice variant baaae 0.0312 0.1405 0.2619
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0034 0.0079 0.0129
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.0084
Schistosoma mansoni cpg binding protein 0.0086 0.0326 0.0326
Plasmodium vivax 6-phosphofructokinase, putative 0.0034 0.0079 0.073
Onchocerca volvulus 0.0046 0.0136 0.0222
Loa Loa (eye worm) inositol-1 0.0035 0.0082 0.0152
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0123 0.0501 0.082
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0034 0.0076 0.0076
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0048 0.0143 0.0143
Echinococcus multilocularis neuropeptide receptor 0.071 0.3298 0.3298
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0034 0.0077 0.0185
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0025 0.0037 0.0037
Echinococcus granulosus peptide allatostatin:somatostatin 0.071 0.3298 0.3298
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0035 0.0083 0.0082
Schistosoma mansoni calpain-7 (C02 family) 0.0024 0.0031 0.0031
Trypanosoma cruzi 60S ribosomal protein L19, putative 0.0024 0.003 0.0188
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0087 0.0333 0.6321
Leishmania major ATP-dependent phosphofructokinase 0.0126 0.0517 0.3264
Echinococcus multilocularis calpain A 0.0064 0.0219 0.0219
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0243 0.1074 0.1074
Onchocerca volvulus Bile acid receptor homolog 0.0048 0.0143 0.0233
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0067 0.0236 0.1479
Schistosoma mansoni 6-phosphofructokinase 0.0126 0.0517 0.0517
Schistosoma mansoni 6-phosphofructokinase 0.0126 0.0517 0.0517
Loa Loa (eye worm) hypothetical protein 0.0034 0.0081 0.015
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0066 0.0229 0.0427
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0064 0.0219 0.0219
Schistosoma mansoni nuclear receptor 0.0022 0.0023 0.0023
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0166 0.0706 0.4454
Echinococcus multilocularis calpain 0.0018 0.0002 0.0002
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0066 0.0229 0.0374
Schistosoma mansoni lipoxygenase 0.0061 0.0205 0.0205
Brugia malayi Protein kinase domain containing protein 0.0018 0.0001 0.0001
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.071 0.3298 0.6149
Onchocerca volvulus 0.071 0.3298 0.5393
Toxoplasma gondii phosphofructokinase PFKII 0.0034 0.0079 0.073
Schistosoma mansoni bromodomain containing protein 0.002 0.0014 0.0013
Brugia malayi nuclear hormone receptor family member nhr-6 0.0022 0.0023 0.0043
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0015 0.0084
Echinococcus multilocularis rhodopsin orphan GPCR 0.071 0.3298 0.3298
Echinococcus multilocularis dna polymerase eta 0.0021 0.0015 0.0015
Plasmodium vivax SET domain protein, putative 0.0165 0.0704 0.6554
Loa Loa (eye worm) hypothetical protein 0.071 0.3298 0.6149
Loa Loa (eye worm) hypothetical protein 0.0025 0.0036 0.0067
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0123 0.0501 0.082
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0157 0.0993
Loa Loa (eye worm) hypothetical protein 0.0022 0.0019 0.0036
Trichomonas vaginalis 60S ribosomal protein L19, putative 0.0024 0.003 0.0049
Echinococcus multilocularis g protein coupled receptor 0.071 0.3298 0.3298
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0086 0.0328 0.0611
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0048 0.0143 0.0266
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0123 0.0501 0.082
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0034 0.0077 0.0185
Schistosoma mansoni calpain C (C02 family) 0.0018 0.0002 0.0002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0201 0.0873 0.0873
Trypanosoma cruzi hypothetical protein, conserved 0.0066 0.0229 0.1444
Trypanosoma brucei hypothetical protein, conserved 0.0112 0.045 0.2833
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0115 0.0465 0.293
Echinococcus multilocularis mitogen activated protein kinase 3 0.0115 0.0465 0.0464
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0066 0.0229 0.0229
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0055 0.0178 0.0178
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0025 0.0036 0.0067
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.0465 0.0464
Plasmodium falciparum histone acetyltransferase GCN5 0.0079 0.0291 1
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0086 0.0324 0.0323
Echinococcus granulosus alpha 1A adrenergic receptor 0.071 0.3298 0.3298
Onchocerca volvulus 0.0114 0.0458 0.0749
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0002 0.0012
Brugia malayi ecdysone receptor 0.0022 0.0023 0.0043
Brugia malayi Calcitonin receptor-like protein seb-1 0.0457 0.2094 0.3904
Onchocerca volvulus 0.0083 0.0313 0.0511
Schistosoma mansoni hypothetical protein 0.0452 0.2068 0.2068
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0136 0.1551

Activities

Activity type Activity value Assay description Source Reference
ED50 (functional) = 28.5 mg kg-1 Anticonvulsant activity by the maximal electroshock test in mice by intraperitoneal administration ChEMBL. 7252982
ED50 (functional) = 31.2 mg kg-1 Anticonvulsant activity was evaluated by the maximal electroshock test in mice,administered orally ChEMBL. 7252982
LD50 (ADMET) = 210 mg kg-1 Lethal dose in mice determined after intraperitoneal administration. ChEMBL. 7252982

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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