Detailed information for compound 303437

Basic information

Technical information
  • TDR Targets ID: 303437
  • Name: (5aR,8aR,9R)-9-(3,4-dihydroxy-5-methoxyphenyl )-5-hydroxy-5a,6,8a,9-tetrahydro-5H-[2]benzof uro[5,6-f][1,3]benzodioxol-8-one
  • MW: 386.352 | Formula: C20H18O8
  • H donors: 3 H acceptors: 4 LogP: 1.52 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc(cc(c1O)O)[C@H]1[C@H]2C(=O)OC[C@@H]2C(c2c1cc1OCOc1c2)O
  • InChi: 1S/C20H18O8/c1-25-15-3-8(2-12(21)19(15)23)16-9-4-13-14(28-7-27-13)5-10(9)18(22)11-6-26-20(24)17(11)16/h2-5,11,16-18,21-23H,6-7H2,1H3/t11-,16+,17-,18?/m0/s1
  • InChiKey: UCILNJOMIKDJGF-KBRCUVENSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • (5aR,8aR,9R)-9-(3,4-dihydroxy-5-methoxy-phenyl)-5-hydroxy-5a,6,8a,9-tetrahydro-5H-isobenzofuro[5,6-f][1,3]benzodioxol-8-one
  • (5aR,8aR,9R)-9-(3,4-dihydroxy-5-methoxyphenyl)-5-hydroxy-5a,6,8a,9-tetrahydro-5H-isobenzofuro[5,6-f][1,3]benzodioxol-8-one
  • (5aR,8aR,9R)-9-(3,4-dihydroxy-5-methoxy-phenyl)-5-hydroxy-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one
  • (5aR,8aR,9R)-9-(3,4-dihydroxy-5-methoxy-phenyl)-5-hydroxy-5a,6,8a,9-tetrahydro-5H-isobenzofurano[5,6-f][1,3]benzodioxol-8-one
  • (5aR,8aR,9R)-9-(3,4-dihydroxy-5-methoxyphenyl)-5-hydroxy-5a,6,8a,9-tetrahydro-5H-isobenzofurano[5,6-f][1,3]benzodioxol-8-one
  • 3',4'-O,O-Didemethylpodophyllotoxin
  • AIDS-030823
  • AIDS030823

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0674 0.774 0.774
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0148 0.0191
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0212 1
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0013 0.000000000045487 0.000000000058772
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0144 0.1536 0.1985
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0084 0.0109
Plasmodium vivax DNA polymerase zeta catalytic subunit, putative 0.0015 0.0022 0.0028
Giardia lamblia Beta tubulin 0.0165 0.1775 0.2271
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0068 0.0637 0.3539
Giardia lamblia DNA polymerase alpha subunit A 0.0046 0.0388 0.0475
Trichomonas vaginalis tubulin alpha chain, putative 0.0067 0.0631 0.0816
Leishmania major beta tubulin 0.0165 0.1775 0.2278
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0073 0.0094
Trypanosoma brucei DNA polymerase zeta catalytic subunit, putative 0.0015 0.0022 0.0009
Onchocerca volvulus 0.002 0.0073 0.0094
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0212 0.0274
Loa Loa (eye worm) tubulin beta-4 chain 0.0165 0.1775 0.2293
Loa Loa (eye worm) hypothetical protein 0.0026 0.0146 0.0188
Trypanosoma brucei zeta tubulin 0.0052 0.0448 0.0561
Trichomonas vaginalis tubulin beta chain, putative 0.0144 0.1536 0.1985
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.005 0.0044
Leishmania major beta tubulin 0.0165 0.1775 0.2278
Mycobacterium tuberculosis Probable dehydrogenase 0.0115 0.1195 0.1528
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0073 0.0094
Toxoplasma gondii target of rapamycin (TOR), putative 0.0036 0.0263 0.034
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0073 0.0094
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0084 0.01
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0068 0.0637 0.075
Loa Loa (eye worm) hypothetical protein 0.0165 0.1773 0.2291
Brugia malayi Cytochrome P450 family protein 0.0024 0.012 0.0155
Echinococcus multilocularis peroxisome assembly protein 26 0.0144 0.1536 0.1536
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0268 0.2983 0.3842
Schistosoma mansoni tubulin subunit epsilon 0.0119 0.1235 0.1456
Trichomonas vaginalis tubulin, putative 0.0165 0.1775 0.2293
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0073 0.0094
Trypanosoma brucei trypanothione reductase 0.0051 0.0437 0.0545
Onchocerca volvulus 0.0067 0.0631 0.0816
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0229 0.0296
Echinococcus granulosus nuclear factor of activated T cells 5 0.0079 0.0767 0.0903
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0018 0.005 0.0044
Onchocerca volvulus 0.002 0.0073 0.0094
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0407 0.0526
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.005 0.0044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0263 0.034
Loa Loa (eye worm) hypothetical protein 0.0165 0.1773 0.2291
Loa Loa (eye worm) DNA-directed DNA polymerase III 0.0015 0.0022 0.0028
Schistosoma mansoni z-protein (S1r protein) 0.0021 0.0084 0.01
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0336 0.0434
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0674 0.774 1
Loa Loa (eye worm) 6-phosphofructokinase 0.0116 0.1206 0.1558
Plasmodium falciparum cysteine proteinase falcipain 3 0.002 0.0073 0.0094
Plasmodium vivax glutathione reductase, putative 0.0051 0.0437 0.0564
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0042 0.0336 0.0415
Loa Loa (eye worm) 6-phosphofructokinase 0.0116 0.1206 0.1558
Echinococcus granulosus tubulin subunit TubB 0.0144 0.1536 0.181
Loa Loa (eye worm) tubulin alpha 2 0.0093 0.0932 0.1204
Onchocerca volvulus Cathepsin L homolog 0.002 0.0073 0.0094
Loa Loa (eye worm) hypothetical protein 0.0036 0.0262 0.0339
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0082 0.0809 0.0809
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0027 0.0163 0.0843
Loa Loa (eye worm) BEN-1 protein 0.0165 0.1775 0.2293
Onchocerca volvulus 0.0165 0.1773 0.2291
Trichomonas vaginalis phosphofructokinase, putative 0.0116 0.1206 0.1558
Brugia malayi Protein kinase domain containing protein 0.0018 0.005 0.0065
Loa Loa (eye worm) latrophilin receptor protein 2 0.0033 0.0229 0.0296
Echinococcus multilocularis Protein lozenge 0.0063 0.0577 0.0577
Giardia lamblia Beta tubulin 0.0165 0.1775 0.2271
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0084 0.0109
Giardia lamblia Epsilon tubulin 0.0052 0.0448 0.0553
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0046 0.0377 0.0487
Echinococcus multilocularis tubulin gamma 1 chain 0.0119 0.1235 0.1235
Trypanosoma cruzi cysteine peptidase, putative 0.0074 0.0715 0.0906
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0033 0.0229 0.0277
Onchocerca volvulus DNA polymerase homolog 0.0015 0.0022 0.0028
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0336 0.0415
Leishmania major epsilon tubulin, putative 0.0119 0.1235 0.158
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.021 0.0271
Trypanosoma cruzi cysteine peptidase, putative 0.0074 0.0715 0.0906
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0016 0.0033 0.0039
Echinococcus multilocularis tubulin alpha 3 chain 0.0144 0.1536 0.1536
Loa Loa (eye worm) phosphatidylinositol 3 0.0048 0.0407 0.0526
Schistosoma mansoni 6-phosphofructokinase 0.0116 0.1206 0.1421
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0165 0.1775 0.1775
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0212 0.0274
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0084 0.01
Schistosoma mansoni hypothetical protein 0.0033 0.0229 0.027
Plasmodium falciparum cysteine repeat modular protein 1 0.0018 0.005 0.0065
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0715 0.0906
Loa Loa (eye worm) hypothetical protein 0.0071 0.0675 0.0872
Leishmania major alpha tubulin 0.0144 0.1536 0.1969
Schistosoma mansoni tubulin subunit beta 0.0165 0.1775 0.2091
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0084 0.01
Onchocerca volvulus 0.0543 0.6208 0.8021
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0044 0.0056
Schistosoma mansoni tar DNA-binding protein 0.0132 0.1388 0.1636
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0048 0.0407 0.0507
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0336 0.0434
Echinococcus multilocularis transmembrane protease serine 3 0.0165 0.1773 0.1773
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0027 0.0163 0.0211
Echinococcus granulosus tubulin alpha 0.0119 0.1235 0.1456
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0033 0.0229 0.0229
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0263 0.034
Trichomonas vaginalis DNA polymerase alpha catalytic subunit, putative 0.0024 0.0125 0.0161
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0021 0.0084 0.01
Entamoeba histolytica hypothetical protein 0.0013 0.000000000045487 0.000000000058772
Echinococcus multilocularis DNA polymerase delta catalytic subunit 0.0015 0.0022 0.0022
Brugia malayi Cathepsin L-like precursor 0.002 0.0073 0.0094
Brugia malayi latrophilin 2 splice variant baaae 0.0071 0.0675 0.0872
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0292 0.0377
Brugia malayi Trypsin family protein 0.0165 0.1773 0.2291
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.005 0.0044
Echinococcus multilocularis tar DNA binding protein 0.0132 0.1388 0.1388
Schistosoma mansoni chromobox protein 0.0081 0.0795 0.0937
Trypanosoma cruzi major cysteine proteinase, putative 0.0058 0.0529 0.0664
Trichomonas vaginalis tubulin gamma chain, putative 0.0119 0.1235 0.1596
Trichomonas vaginalis tubulin beta chain, putative 0.0144 0.1536 0.1985
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0148 0.0191
Echinococcus multilocularis lamin 0.0057 0.0509 0.0509
Echinococcus granulosus tissue type plasminogen activator 0.0018 0.005 0.0059
Loa Loa (eye worm) hypothetical protein 0.0499 0.5682 0.7342
Echinococcus granulosus Mastin 0.0165 0.1773 0.2089
Plasmodium vivax hypothetical protein, conserved 0.0013 0.000000000045487 0.000000000058772
Leishmania major beta tubulin 0.0165 0.1775 0.2278
Toxoplasma gondii DNA polymerase (pol2) superfamily protein 0.0044 0.0365 0.0472
Schistosoma mansoni cercarial elastase (S01 family) 0.0165 0.1773 0.2089
Schistosoma mansoni cercarial elastase (S01 family) 0.0165 0.1773 0.2089
Giardia lamblia NADH oxidase lateral transfer candidate 0.0018 0.005 0.0036
Echinococcus granulosus tubulin alpha chain 0.0144 0.1536 0.181
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0013 0.000000000045487 0.000000000058772
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.0112 0.0144
Echinococcus multilocularis tubulin subunit TubB 0.0144 0.1536 0.1536
Plasmodium vivax SET domain protein, putative 0.0069 0.0653 0.0844
Mycobacterium leprae conserved hypothetical protein 0.0042 0.0336 0.2407
Echinococcus multilocularis lamin dm0 0.0057 0.0509 0.0509
Leishmania major alpha tubulin 0.0144 0.1536 0.1969
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0148 0.0192
Loa Loa (eye worm) tubulin gamma chain 0.0119 0.1235 0.1596
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0069 0.0653 0.0769
Giardia lamblia Alpha-tubulin 0.0144 0.1536 0.1962
Loa Loa (eye worm) RGS-3 protein 0.0021 0.0084 0.0109
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0021 0.0084 0.01
Echinococcus granulosus L aminoadipate semialdehyde 0.0097 0.0979 0.1153
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0073 0.0073
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0073 0.0073
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0018 0.005 0.0064
Loa Loa (eye worm) hypothetical protein 0.0021 0.0084 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0222 0.0286
Trichomonas vaginalis tubulin gamma chain, putative 0.0165 0.1775 0.2293
Leishmania major beta tubulin 0.0165 0.1775 0.2278
Echinococcus granulosus lamin dm0 0.0057 0.0509 0.06
Brugia malayi Calcitonin receptor-like protein seb-1 0.0104 0.1059 0.1369
Loa Loa (eye worm) hypothetical protein 0.0057 0.0509 0.0658
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0016 0.0033 0.0033
Echinococcus multilocularis Tubulin beta 2C chain 0.0165 0.1775 0.1775
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0084 0.01
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0033 0.0043
Trichomonas vaginalis tubulin epsilon chain, putative 0.0144 0.1536 0.1985
Brugia malayi phosphofructokinase 0.0116 0.1206 0.1558
Echinococcus granulosus peroxisome assembly protein 26 0.0144 0.1536 0.181
Brugia malayi Tubulin alpha-2 chain 0.0144 0.1536 0.1985
Schistosoma mansoni hypothetical protein 0.0165 0.1773 0.2089
Loa Loa (eye worm) hypothetical protein 0.0027 0.016 0.0207
Plasmodium vivax vivapain-2 0.002 0.0073 0.0094
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0165 0.1773 0.1773
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0448 0.0579
Schistosoma mansoni laminin gamma-3 chain 0.0026 0.0146 0.0172
Echinococcus granulosus beta LACTamase domain containing family member 0.0042 0.0336 0.0395
Echinococcus granulosus tubulin alpha chain 0.0144 0.1536 0.181
Echinococcus granulosus cathepsin l cysteine peptidase 0.002 0.0073 0.0086
Echinococcus granulosus lamin 0.0057 0.0509 0.06
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0013 0.000000000045487 0.000000000058772
Schistosoma mansoni DNA polymerase zeta catalytic subunit 0.0015 0.0022 0.0026
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.005 0.0046
Trypanosoma brucei beta tubulin 0.0119 0.1235 0.158
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0033 0.0229 0.027
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0052 0.0448 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0066 0.0616 0.0725
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0084 0.01
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0093 0.0932 0.1204
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.012 0.0155
Leishmania major alpha tubulin 0.0144 0.1536 0.1969
Leishmania major zeta tubulin, putative 0.0052 0.0448 0.0561
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0068 0.0637 0.3539
Echinococcus multilocularis glycoprotein Antigen 5 0.0165 0.1773 0.1773
Schistosoma mansoni cercarial elastase (S01 family) 0.0165 0.1773 0.2089
Loa Loa (eye worm) glutathione reductase 0.0051 0.0437 0.0564
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0013 0.000000000045487 0.000000000045487
Trichomonas vaginalis chromobox protein, putative 0.0081 0.0795 0.1027
Trypanosoma cruzi DNA polymerase delta catalytic subunit, putative 0.0015 0.0022 0.0009
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.005 0.0044
Echinococcus multilocularis Tubulin alpha 1 chain 0.0144 0.1536 0.1536
Echinococcus granulosus tubulin beta 1 chain 0.0165 0.1775 0.2091
Echinococcus granulosus pikachurin 0.0026 0.0146 0.0172
Echinococcus granulosus tubulin alpha chain 0.0144 0.1536 0.181
Entamoeba histolytica tubulin family protein 0.0165 0.1775 0.2293
Brugia malayi Cytochrome P450 family protein 0.0053 0.047 0.0607
Loa Loa (eye worm) alpha-tubulin 0.0144 0.1536 0.1985
Echinococcus granulosus tubulin beta 4A class IVa 0.0165 0.1775 0.2091
Toxoplasma gondii cathepsin CPL 0.002 0.0073 0.0094
Echinococcus multilocularis geminin 0.0388 0.439 0.439
Loa Loa (eye worm) trypsin family protein 0.0165 0.1773 0.2291
Schistosoma mansoni tubulin subunit alpha 0.0144 0.1536 0.181
Brugia malayi beta-lactamase family protein 0.0042 0.0336 0.0434
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0165 0.0195
Loa Loa (eye worm) hypothetical protein 0.0075 0.0727 0.094
Onchocerca volvulus 0.0013 0.00000004398 0.000000056824
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0068 0.0637 0.0637
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0033 0.0229 0.027
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0084 0.0109
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.000000000045487 0.000000000058772
Echinococcus multilocularis dnaJ subfamily B 0.0437 0.4967 0.4967
Mycobacterium leprae conserved hypothetical protein 0.0027 0.0163 0.1114
Schistosoma mansoni 6-phosphofructokinase 0.0116 0.1206 0.1421
Brugia malayi beta-tubulin, identical 0.0165 0.1775 0.2293
Trypanosoma cruzi tubulin delta chain 0.0052 0.0448 0.0561
Entamoeba histolytica tubulin family protein 0.0165 0.1775 0.2293
Plasmodium falciparum glutathione reductase 0.0018 0.005 0.0064
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0073 0.0094
Onchocerca volvulus 0.0056 0.0502 0.0649
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0015 0.0023 0.003
Schistosoma mansoni cercarial elastase (S01 family) 0.0165 0.1773 0.2089
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0263 0.034
Echinococcus granulosus tubulin epsilon chain 0.0119 0.1235 0.1456
Echinococcus granulosus tumor protein p63 0.0361 0.4076 0.4803
Loa Loa (eye worm) MH2 domain-containing protein 0.0134 0.1418 0.1832
Echinococcus granulosus alpha tubulin 0.0144 0.1536 0.181
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0034
Leishmania major gamma-tubulin 0.0119 0.1235 0.158
Echinococcus multilocularis neuropeptide receptor A26 0.0539 0.6154 0.6154
Echinococcus multilocularis microtubule associated protein 2 0.0738 0.8487 0.8487
Leishmania major alpha tubulin 0.0144 0.1536 0.1969
Onchocerca volvulus 0.0018 0.005 0.0065
Trypanosoma brucei beta tubulin 0.0165 0.1775 0.2278
Entamoeba histolytica hypothetical protein 0.0021 0.0084 0.0109
Onchocerca volvulus 0.002 0.0073 0.0094
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0069 0.0653 0.0844
Trypanosoma cruzi trypanothione reductase, putative 0.0051 0.0437 0.0545
Schistosoma mansoni lamin 0.0057 0.0509 0.06
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0084 0.01
Mycobacterium ulcerans 6-phosphofructokinase 0.0116 0.1206 0.6773
Schistosoma mansoni tubulin subunit alpha 0.0144 0.1536 0.181
Leishmania major cytochrome p450-like protein 0.0024 0.012 0.0135
Echinococcus granulosus tubulin gamma 1 chain 0.0119 0.1235 0.1456
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0715 0.0906
Loa Loa (eye worm) hypothetical protein 0.0042 0.0336 0.0434
Schistosoma mansoni lamin 0.0057 0.0509 0.06
Entamoeba histolytica hypothetical protein 0.0082 0.0809 0.1046
Loa Loa (eye worm) cytochrome P450 0.0015 0.0015 0.002
Brugia malayi SET domain containing protein 0.0016 0.0037 0.0048
Brugia malayi Cytochrome P450 family protein 0.0024 0.012 0.0155
Schistosoma mansoni intermediate filament proteins 0.0057 0.0509 0.06
Echinococcus granulosus death domain containing protein 0.0015 0.0024 0.0029
Echinococcus multilocularis Chromo domain 0.0013 0.000000000045487 0.000000000045487
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0715 0.0906
Brugia malayi Intermediate filament tail domain containing protein 0.0057 0.0509 0.0658
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0027 0.0163 0.0148
Loa Loa (eye worm) hypothetical protein 0.0042 0.0336 0.0434
Leishmania major beta tubulin 0.0165 0.1775 0.2278
Brugia malayi eukaryotic initiation factor 4A 0.0674 0.774 1
Schistosoma mansoni hypothetical protein 0.0071 0.0675 0.0795
Leishmania major eukaryotic initiation factor 4a, putative 0.0674 0.774 1
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0018 0.005 0.0064
Trichomonas vaginalis chromobox protein, putative 0.0049 0.0418 0.054
Trichomonas vaginalis tubulin gamma chain, putative 0.0119 0.1235 0.1596
Plasmodium vivax thioredoxin reductase, putative 0.0051 0.0437 0.0564
Echinococcus multilocularis Regulator of G protein signaling 20 0.0021 0.0084 0.0084
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0048 0.0407 0.0507
Echinococcus granulosus tubulin alpha 3 chain 0.0144 0.1536 0.181
Loa Loa (eye worm) abnormal epIthelia family member 0.0026 0.0146 0.0188
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0033 0.0023
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0212 0.0274
Mycobacterium ulcerans beta-lactamase 0.0042 0.0336 0.1823
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0084 0.01
Echinococcus granulosus Chromobox protein 3 0.0013 0.00000004398 0.000000051821
Trypanosoma cruzi tubulin delta chain 0.0052 0.0448 0.0561
Echinococcus granulosus tar DNA binding protein 0.0132 0.1388 0.1636
Brugia malayi Kringle domain containing protein 0.0018 0.005 0.0065
Leishmania major hypothetical protein, conserved 0.0018 0.005 0.0046
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0024 0.0024
Echinococcus multilocularis beta tubulin 0.0165 0.1775 0.1775
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0212 0.0274
Leishmania major beta tubulin 0.0165 0.1775 0.2278
Echinococcus granulosus beta-adrenergic receptor kinase 0.0021 0.0084 0.01
Plasmodium vivax DNA polymerase alpha, putative 0.0044 0.0365 0.0472
Loa Loa (eye worm) cytochrome P450 family protein 0.0053 0.047 0.0607
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0018 0.005 0.0195
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0073 0.0094
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0042 0.0336 0.1823
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0212 0.0274
Loa Loa (eye worm) hypothetical protein 0.0026 0.0146 0.0188
Loa Loa (eye worm) hypothetical protein 0.0097 0.0979 0.1265
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0024 0.0024
Trypanosoma brucei alpha tubulin 0.0144 0.1536 0.1969
Echinococcus multilocularis survival motor neuron protein 1 0.0276 0.3071 0.3071
Schistosoma mansoni cellular tumor antigen P53 0.0053 0.0464 0.0547
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0084 0.0109
Brugia malayi Tubulin gamma chain 0.0119 0.1235 0.1596
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0165 0.1773 0.2089
Loa Loa (eye worm) hypothetical protein 0.0013 0.000000000045487 0.000000000058772
Entamoeba histolytica hypothetical protein 0.0021 0.0084 0.0109
Leishmania major beta tubulin 0.0165 0.1775 0.2278
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.02 0.0259
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.000000000045487 0.000000000058772
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0674 0.774 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0084 0.0109
Loa Loa (eye worm) hypothetical protein 0.0077 0.0749 0.0968
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0021 0.0084 0.0084
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0229 0.0296
Echinococcus granulosus eukaryotic initiation factor 4A 0.0674 0.774 0.912
Loa Loa (eye worm) tubulin alpha 2 0.0026 0.0145 0.0187
Brugia malayi tubulin alpha chain - mouse 0.0144 0.1536 0.1985
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0081 0.0105
Trichomonas vaginalis tubulin beta chain, putative 0.0165 0.1775 0.2293
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0181 0.0234
Leishmania major alpha tubulin 0.0144 0.1536 0.1969
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0033 0.0043
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.005 0.0044
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0715 0.0906
Brugia malayi hypothetical protein 0.0165 0.1773 0.2291
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0013 0.000000000045487 0.000000000058772
Loa Loa (eye worm) hypothetical protein 0.0026 0.0146 0.0188
Brugia malayi hypothetical protein 0.0276 0.3071 0.3967
Echinococcus multilocularis cysteine protease 0.002 0.0073 0.0073
Brugia malayi DNA polymerase alpha catalytic subunit 0.0044 0.0365 0.0472
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0057 0.0509 0.0658
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0377 0.0487
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0292 0.0377
Loa Loa (eye worm) hypothetical protein 0.0021 0.0084 0.0109
Echinococcus granulosus GPCR family 2 0.0033 0.0229 0.027
Leishmania major cathepsin L-like protease 0.0074 0.0715 0.0906
Brugia malayi hypothetical protein 0.0499 0.5682 0.7342
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.016 0.0187
Mycobacterium tuberculosis Cell division protein FtsZ 0.0052 0.0448 0.0561
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0038 0.0293 0.0359
Trypanosoma brucei beta tubulin 0.0165 0.1775 0.2278
Schistosoma mansoni hypothetical protein 0.0165 0.1773 0.2089
Mycobacterium tuberculosis Probable reductase 0.0115 0.1195 0.1528
Onchocerca volvulus 0.0031 0.0204 0.0264
Plasmodium falciparum eukaryotic initiation factor 4A 0.0674 0.774 1
Brugia malayi Tubulin beta chain 0.0067 0.0631 0.0816
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0024 0.0032
Loa Loa (eye worm) hypothetical protein 0.0046 0.0377 0.0487
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.0674 0.774 1
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0084 0.01
Entamoeba histolytica phosphofructokinase, putative 0.0116 0.1206 0.1558
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0115 0.1195 0.1528
Loa Loa (eye worm) fibroinase 0.002 0.0073 0.0094
Trichomonas vaginalis tubulin epsilon chain, putative 0.0052 0.0448 0.0579
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0068 0.0637 0.0805
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0165 0.1773 0.2089
Trypanosoma brucei beta tubulin 0.0165 0.1775 0.2278
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0033 0.0229 0.0229
Trypanosoma brucei hypothetical protein, conserved 0.0042 0.0336 0.0415
Leishmania major beta tubulin 0.0165 0.1775 0.2278
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0674 0.774 1
Onchocerca volvulus 0.002 0.0073 0.0094
Brugia malayi RNA recognition motif domain containing protein 0.0132 0.1388 0.1794
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0018 0.005 0.0195
Trichomonas vaginalis chromobox protein, putative 0.0049 0.0418 0.054
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0016 0.0033 0.0023
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0021 0.0084 0.0109
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0024 0.0032
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0081 0.0105
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0229 0.0277
Plasmodium vivax RNA helicase-1, putative 0.0674 0.774 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0033 0.0229 0.0296
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0027 0.0163 0.7002
Echinococcus granulosus tubulin alpha 1C chain 0.0144 0.1536 0.181
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0079 0.0767 0.0767
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0021 0.0084 0.0109
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0042 0.0336 0.0434
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0069 0.0653 0.0653
Brugia malayi Trypsin family protein 0.0165 0.1773 0.2291
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0018 0.005 0.0064
Schistosoma mansoni cpg binding protein 0.0031 0.0204 0.024
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0084 0.0109
Trypanosoma brucei epsilon tubulin 0.0119 0.1235 0.158
Echinococcus granulosus Regulator of G protein signaling 20 0.0021 0.0084 0.01
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0715 0.0906
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0073 0.0094
Entamoeba histolytica hypothetical protein 0.0082 0.0809 0.1046
Brugia malayi DNA polymerase family B, exonuclease domain containing protein 0.0015 0.0022 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0073 0.0094
Echinococcus multilocularis Tubulin beta 2C chain 0.0165 0.1775 0.1775
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0051 0.0437 0.0545
Leishmania major beta tubulin 0.0165 0.1775 0.2278
Loa Loa (eye worm) hypothetical protein 0.0021 0.0084 0.0109
Plasmodium falciparum tubulin beta chain 0.0165 0.1775 0.2293
Trichomonas vaginalis tubulin epsilon chain, putative 0.0165 0.1775 0.2293
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0015 0.0021 0.0021
Brugia malayi hypothetical protein 0.0013 0.0002 0.0002
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.016 0.0207
Echinococcus granulosus expressed protein 0.0399 0.4519 0.5325
Brugia malayi Trypsin family protein 0.0165 0.1773 0.2291
Echinococcus granulosus transmembrane protease serine 3 0.0165 0.1773 0.2089
Giardia lamblia Gamma tubulin 0.0119 0.1235 0.1572
Trypanosoma brucei cytochrome P450, putative 0.0024 0.012 0.0135
Loa Loa (eye worm) hypothetical protein 0.0165 0.1773 0.2291
Brugia malayi Tubulin beta-1 chain 0.0165 0.1775 0.2293
Echinococcus multilocularis enteropeptidase 0.0165 0.1773 0.1773
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0674 0.774 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0084 0.0109
Trypanosoma brucei tubulin gamma chain 0.0119 0.1235 0.158
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0165 0.1773 0.2291
Schistosoma mansoni cercarial elastase (S01 family) 0.0165 0.1773 0.2089
Entamoeba histolytica tubulin gamma chain 0.0119 0.1235 0.1596
Trichomonas vaginalis DNA helicase recq1, putative 0.0023 0.0112 0.0144
Echinococcus granulosus slit 2 protein 0.0026 0.0146 0.0172
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0212 0.0274
Brugia malayi laminin alpha chain 0.0026 0.0146 0.0188
Brugia malayi beta-lactamase family protein 0.0042 0.0336 0.0434
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0048 0.0407 0.0526
Loa Loa (eye worm) beta-tubulin 0.0165 0.1775 0.2293
Plasmodium falciparum tubulin gamma chain 0.0119 0.1235 0.1596
Trypanosoma cruzi DNA polymerase epsilon catalytic subunit, putative 0.0015 0.0022 0.0009
Onchocerca volvulus 0.0165 0.1773 0.2291
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0081 0.0105
Loa Loa (eye worm) TK/ROR protein kinase 0.0018 0.005 0.0065
Schistosoma mansoni hypothetical protein 0.0015 0.0024 0.0029
Echinococcus granulosus tubulin alpha 1C chain 0.0144 0.1536 0.181
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0033 0.0229 0.0296
Loa Loa (eye worm) papain family cysteine protease containing protein 0.002 0.0073 0.0094
Leishmania major beta tubulin 0.0165 0.1775 0.2278
Echinococcus granulosus dnaJ subfamily B 0.0437 0.4967 0.5853
Leishmania major beta tubulin 0.0165 0.1775 0.2278
Echinococcus multilocularis pikachurin 0.0026 0.0146 0.0146
Trichomonas vaginalis tubulin beta chain, putative 0.0144 0.1536 0.1985
Trypanosoma cruzi cytochrome P450, putative 0.0024 0.012 0.0135
Brugia malayi Tubulin alpha-2 chain 0.0144 0.1536 0.1985
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0073 0.0094
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0115 0.1195 0.8867
Entamoeba histolytica tubulin alpha chain, putative 0.0144 0.1536 0.1985
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0079 0.0102
Schistosoma mansoni tubulin subunit beta 0.0165 0.1775 0.2091
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0073 0.0094
Brugia malayi Tubulin alpha chain 0.0144 0.1536 0.1985
Schistosoma mansoni hypothetical protein 0.0437 0.4967 0.5853
Onchocerca volvulus 0.0165 0.1773 0.2291
Plasmodium falciparum tubulin delta chain, putative 0.0052 0.0448 0.0579
Plasmodium falciparum DNA polymerase alpha catalytic subunit A 0.0016 0.0026 0.0034
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0017 0.0044 0.0056
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0116 0.1206 0.1541
Echinococcus granulosus Tubulin beta 2C chain 0.0165 0.1775 0.2091
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0229 0.0277
Trypanosoma cruzi trypanothione reductase, putative 0.0018 0.005 0.0044
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0674 0.774 0.912
Leishmania major cathepsin L-like protease 0.002 0.0073 0.0075
Echinococcus multilocularis beta tubulin 0.0165 0.1775 0.1775
Leishmania major beta tubulin 0.0165 0.1775 0.2278
Brugia malayi beta-lactamase 0.0042 0.0336 0.0434
Leishmania major DNA polymerase epsilon catalytic subunit, putative 0.0015 0.0022 0.0009
Schistosoma mansoni hypothetical protein 0.0055 0.0492 0.058
Schistosoma mansoni cercarial elastase (S01 family) 0.0165 0.1773 0.2089
Loa Loa (eye worm) hypothetical protein 0.002 0.0073 0.0094
Plasmodium vivax tubulin epsilon chain, putative 0.0119 0.1235 0.1596
Brugia malayi cytochrome P450 0.0015 0.0015 0.002
Plasmodium falciparum thioredoxin reductase 0.0018 0.005 0.0064
Echinococcus granulosus Tubulin alpha 1 chain 0.0144 0.1536 0.181
Trypanosoma cruzi cytochrome P450, putative 0.0024 0.012 0.0135
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0056 0.0502 0.0649
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0715 0.0906
Schistosoma mansoni hypothetical protein 0.0033 0.0229 0.027
Brugia malayi Thrombospondin N-terminal -like domain containing protein 0.0026 0.0146 0.0188
Loa Loa (eye worm) heterochromatin protein 1 0.0081 0.0795 0.1027
Plasmodium falciparum DNA polymerase delta catalytic subunit 0.0015 0.0022 0.0028
Schistosoma mansoni microtubule-associated protein tau 0.0738 0.8487 1
Mycobacterium tuberculosis Probable hydrolase 0.0042 0.0336 0.0415
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0104 0.1059 0.1369
Echinococcus multilocularis tubulin alpha chain 0.0144 0.1536 0.1536
Echinococcus multilocularis thioredoxin glutathione reductase 0.0051 0.0437 0.0437
Echinococcus multilocularis slit 2 protein 0.0026 0.0146 0.0146
Schistosoma mansoni blooms syndrome DNA helicase 0.0018 0.0055 0.0065
Schistosoma mansoni netrin receptor unc5 0.0015 0.0024 0.0029
Mycobacterium leprae cell division protein FtsZ 0.0052 0.0448 0.3254
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0263 0.034
Trichomonas vaginalis set domain proteins, putative 0.0543 0.6206 0.8019
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0023 0.0111 0.0123
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0048 0.0407 0.0407
Trypanosoma brucei alpha tubulin, putative 0.0067 0.0631 0.0798
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0016 0.0033 0.0023
Echinococcus granulosus Tubulin beta 2C chain 0.0165 0.1775 0.2091
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0033 0.0229 0.0229
Loa Loa (eye worm) hypothetical protein 0.0053 0.0464 0.0599
Trypanosoma brucei alpha tubulin 0.0144 0.1536 0.1969
Brugia malayi hypothetical protein 0.0143 0.1516 0.1959
Entamoeba histolytica tubulin alpha-1 chain 0.0144 0.1536 0.1985
Onchocerca volvulus 0.0082 0.0809 0.1045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0148 0.0192
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0033 0.0229 0.027
Loa Loa (eye worm) hypothetical protein 0.0143 0.1516 0.1959
Trichomonas vaginalis DNA polymerase zeta catalytic subunit, putative 0.0015 0.0022 0.0028
Entamoeba histolytica hypothetical protein 0.0082 0.0809 0.1046
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0027 0.0163 0.0211
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.016 0.0207
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0048 0.0407 0.048
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0033 0.0043
Plasmodium falciparum glutathione reductase 0.0051 0.0437 0.0564
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0073 0.0094
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0049 0.0418 0.054
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0084 0.0084
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0448 0.0579
Plasmodium falciparum thioredoxin reductase 0.0051 0.0437 0.0564
Trichomonas vaginalis glutathione reductase, putative 0.0018 0.005 0.0064
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0084 0.0084
Schistosoma mansoni tar DNA-binding protein 0.0132 0.1388 0.1636
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0073 0.0086
Trypanosoma cruzi target of rapamycin kinase 3 0.0038 0.0293 0.0359
Schistosoma mansoni hypothetical protein 0.0013 0.000000000045487 0.000000000053597
Trichomonas vaginalis penicillin-binding protein, putative 0.0042 0.0336 0.0434
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0336 0.0434
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0073 0.0094
Leishmania major beta tubulin 0.0165 0.1775 0.2278
Trichomonas vaginalis chromobox protein, putative 0.0081 0.0795 0.1027
Toxoplasma gondii beta-1 tubulin, putative 0.0165 0.1775 0.2293
Toxoplasma gondii beta-tubulin, putative 0.0165 0.1775 0.2293
Entamoeba histolytica cysteine protease, putative 0.002 0.0073 0.0094
Onchocerca volvulus 0.0042 0.0336 0.0434
Trypanosoma cruzi cysteine peptidase, putative 0.0074 0.0715 0.0906
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0081 0.0105
Giardia lamblia GTOR 0.0048 0.0407 0.0499
Toxoplasma gondii DNA polymerase family B protein 0.0015 0.0022 0.0028
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0016 0.0033 0.0023
Trypanosoma brucei DNA polymerase alpha catalytic subunit 0.0024 0.0125 0.0142
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0715 0.0906
Toxoplasma gondii kringle domain-containing protein 0.0018 0.005 0.0065
Toxoplasma gondii NADPH-glutathione reductase 0.0018 0.005 0.0064
Mycobacterium ulcerans cell division protein FtsZ 0.0052 0.0448 0.2464
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0674 0.774 0.912
Echinococcus granulosus tubulin alpha 3 chain 0.0144 0.1536 0.181
Loa Loa (eye worm) tubulin alpha-2 chain 0.0144 0.1536 0.1985
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0013 0.000000000045487 0.000000000058772
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0073 0.0094
Mycobacterium tuberculosis Probable esterase LipL 0.0042 0.0336 0.0415
Loa Loa (eye worm) hypothetical protein 0.0056 0.0497 0.0642
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0033 0.0229 0.0277
Echinococcus granulosus microtubule associated protein 2 0.0738 0.8487 1
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0018 0.005 0.0064
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0018 0.005 0.0044
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0165 0.1773 0.2089
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0073 0.0094
Echinococcus multilocularis dna polymerase epsilon catalytic subunit a 0.0015 0.0022 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0084 0.0109
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0018 0.005 0.0044
Trichomonas vaginalis tubulin alpha chain, putative 0.0119 0.1235 0.1596
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0042 0.0336 0.0434
Leishmania major phosphopantetheinyl transferase-like protein 0.0027 0.0163 0.0192
Brugia malayi regulator of G-protein signaling rgs-7 0.0021 0.0084 0.0109
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.002 0.0073 0.0094
Schistosoma mansoni survival motor neuron protein 0.0056 0.0502 0.0592
Echinococcus granulosus tubulin delta chain 0.0052 0.0448 0.0528
Trichomonas vaginalis tubulin alpha chain, putative 0.0067 0.0631 0.0816
Schistosoma mansoni slit 0.0026 0.0146 0.0172
Loa Loa (eye worm) alpha-tubulin 0.0144 0.1536 0.1985
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.005 0.0044
Echinococcus granulosus neurogenic locus notch protein 0.0026 0.0146 0.0172
Echinococcus multilocularis tubulin alpha chain 0.0144 0.1536 0.1536
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0033 0.0043
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0084 0.0084
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0021 0.0084 0.0109
Trypanosoma cruzi beta tubulin, putative 0.0165 0.1775 0.2278
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0263 0.034
Loa Loa (eye worm) phosphatidylinositol 3 0.0016 0.0033 0.0043
Onchocerca volvulus 0.002 0.0073 0.0094
Echinococcus multilocularis tubulin alpha 3 chain 0.0144 0.1536 0.1536
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0212 1
Toxoplasma gondii alpha tubulin TUBA1 0.0144 0.1536 0.1985
Brugia malayi isocitrate dehydrogenase 0.0033 0.0229 0.0296
Echinococcus multilocularis tubulin alpha chain 0.0144 0.1536 0.1536
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0042 0.0336 0.0395
Schistosoma mansoni DNA polymerase alpha catalytic subunit 0.0021 0.0085 0.01
Loa Loa (eye worm) hypothetical protein 0.0165 0.1773 0.2291
Onchocerca volvulus Cathepsin F homolog 0.002 0.0073 0.0094
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.005 0.0044
Schistosoma mansoni hypothetical protein 0.0388 0.439 0.5172
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0067 0.0631 0.0816
Plasmodium falciparum cysteine proteinase falcipain 2b 0.002 0.0073 0.0094
Onchocerca volvulus Huntingtin homolog 0.0143 0.1516 0.1959
Echinococcus granulosus bloom syndrome protein 0.0023 0.0112 0.0132
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0081 0.0105
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.016 0.0187
Brugia malayi Cathepsin L-like precursor 0.002 0.0073 0.0094
Trichomonas vaginalis tubulin beta chain, putative 0.0067 0.0631 0.0816
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0068 0.0639 0.0808
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0181 0.0234
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0033 0.0043
Echinococcus granulosus Tubulin beta 2C chain 0.0165 0.1775 0.2091
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0116 0.1206 0.8946
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0715 0.0906
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0069 0.0653 0.0769
Plasmodium vivax delta tubulin, putative 0.0052 0.0448 0.0579
Trichomonas vaginalis DNA polymerase II, putative 0.0024 0.0125 0.0161
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0015 0.0021 0.0024
Plasmodium falciparum tubulin epsilon chain, putative 0.0119 0.1235 0.1596
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0212 0.0274
Schistosoma mansoni hypothetical protein 0.0015 0.0015 0.0018
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0119 0.1235 0.1596
Loa Loa (eye worm) hypothetical protein 0.0144 0.1536 0.1985
Entamoeba histolytica phosphofructokinase, putative 0.0116 0.1206 0.1558
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0212 0.0274
Loa Loa (eye worm) hypothetical protein 0.0042 0.0336 0.0434
Trypanosoma cruzi tubulin gamma chain 0.0119 0.1235 0.158
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0048 0.0407 0.0507
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0477 0.5435 0.7022
Brugia malayi hypothetical protein 0.0021 0.0084 0.0109
Brugia malayi hypothetical protein 0.0017 0.0048 0.0062
Brugia malayi hypothetical protein 0.0021 0.0084 0.0109
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0674 0.774 1
Toxoplasma gondii ABC1 family protein 0.0042 0.0336 0.0434
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.005 0.0044
Trichomonas vaginalis tubulin epsilon chain, putative 0.0144 0.1536 0.1985
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0073 0.0094
Echinococcus granulosus Ankyrin 0.0016 0.0026 0.0031
Trypanosoma cruzi alpha tubulin, putative 0.0144 0.1536 0.1969
Loa Loa (eye worm) beta-lactamase 0.0042 0.0336 0.0434
Loa Loa (eye worm) hypothetical protein 0.0021 0.0084 0.0109
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0021 0.0084 0.0109
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0018 0.005 0.0064
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0165 0.1773 0.2089
Mycobacterium ulcerans esterase/lipase LipP 0.0042 0.0336 0.1823
Leishmania major alpha tubulin 0.0144 0.1536 0.1969
Giardia lamblia Alpha-tubulin 0.0144 0.1536 0.1962
Echinococcus multilocularis cysteine protease 0.002 0.0073 0.0073
Brugia malayi tubulin alpha-2 chain 0.0144 0.1536 0.1985
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0073 0.0073
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0015 0.0024 0.0032
Loa Loa (eye worm) intermediate filament protein 0.0057 0.0509 0.0658
Echinococcus multilocularis tubulin subunit beta 0.0165 0.1775 0.1775
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0027 0.0163 0.0211
Mycobacterium ulcerans hypothetical protein 0.0165 0.1773 1
Brugia malayi laminin-like protein K08C7.3 precursor 0.0026 0.0146 0.0188
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0073 0.0094
Echinococcus granulosus neuropeptide receptor A26 0.0539 0.6154 0.7251
Brugia malayi 6-phosphofructokinase 0.0116 0.1206 0.1558
Leishmania major hypothetical protein, conserved 0.0042 0.0336 0.0415
Mycobacterium tuberculosis Conserved protein 0.0042 0.0336 0.0415
Onchocerca volvulus DNA polymerase alpha catalytic subunit homolog 0.0075 0.0727 0.094
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0165 0.1773 0.2089
Trypanosoma brucei alpha tubulin 0.0144 0.1536 0.1969
Echinococcus granulosus cytochrome P450 2K1 0.0015 0.0015 0.0018
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0165 0.1773 0.2089
Entamoeba histolytica hypothetical protein 0.0027 0.0163 0.0211
Brugia malayi 6-phosphofructokinase 0.0116 0.1206 0.1558
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0073 0.0094
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0024 0.0029
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0021 0.0084 0.0109
Brugia malayi A-kinase anchor protein 10, precursor 0.0021 0.0084 0.0109
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0212 0.0274
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0081 0.0105
Mycobacterium ulcerans hypothetical protein 0.0042 0.0336 0.1823
Loa Loa (eye worm) tubulin beta chain 0.0165 0.1775 0.2293
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0068 0.0637 0.0751
Echinococcus granulosus chromobox protein 1 0.0081 0.0795 0.0937
Schistosoma mansoni chromobox protein 0.0081 0.0795 0.0937
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0115 0.1195 0.1528
Echinococcus granulosus chromobox protein 1 0.0081 0.0795 0.0937
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0292 0.0377
Onchocerca volvulus DNA polymerase delta catalytic subunit homolog 0.0015 0.0022 0.0028
Schistosoma mansoni tubulin subunit beta 0.0165 0.1775 0.2091
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.02 0.0259
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0073 0.0094
Onchocerca volvulus 0.0057 0.0509 0.0658
Trypanosoma brucei epsilon tubulin 0.0119 0.1235 0.158
Echinococcus granulosus Tubulin alpha 1 chain 0.0144 0.1536 0.181
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0084 0.01
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0132 0.1388 0.1794
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0204 0.0264
Trichomonas vaginalis DNA polymerase delta catalytic subunit, putative 0.0015 0.0022 0.0028
Loa Loa (eye worm) tubulin alpha-3 chain 0.0077 0.0749 0.0968
Entamoeba histolytica DNA polymerase delta catalytic subunit, putative 0.0015 0.0022 0.0028
Echinococcus granulosus survival motor neuron protein 1 0.0276 0.3071 0.3618
Leishmania major cysteine peptidase A (CPA) 0.002 0.0073 0.0075
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0407 0.0526
Brugia malayi Protein kinase domain containing protein 0.0015 0.0024 0.0032
Onchocerca volvulus 0.0036 0.0262 0.0339
Echinococcus multilocularis tubulin alpha 1C chain 0.0144 0.1536 0.1536
Loa Loa (eye worm) hypothetical protein 0.0276 0.3071 0.3967
Echinococcus multilocularis chromobox protein 1 0.0081 0.0795 0.0795
Loa Loa (eye worm) hypothetical protein 0.0033 0.0229 0.0296
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0212 0.0274
Onchocerca volvulus 0.0499 0.5682 0.7342
Echinococcus granulosus Tubulin beta 2C chain 0.0165 0.1775 0.2091
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0018 0.005 0.0044
Leishmania major cathepsin L-like protease 0.0074 0.0715 0.0906
Trichomonas vaginalis phosphofructokinase, putative 0.0116 0.1206 0.1558
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0068 0.0637 0.0751
Trichomonas vaginalis tubulin beta chain, putative 0.0144 0.1536 0.1985
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0077 0.0749 0.0968
Loa Loa (eye worm) BEN-1 protein 0.0165 0.1775 0.2293
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0081 0.0105
Plasmodium falciparum alpha tubulin 2 0.0144 0.1536 0.1985
Loa Loa (eye worm) runx1 0.0063 0.0577 0.0745
Brugia malayi Tubulin alpha chain 0.0052 0.0448 0.0579
Schistosoma mansoni cell polarity protein 0.0026 0.0146 0.0172
Schistosoma mansoni cytochrome P450 0.0015 0.0015 0.0018
Brugia malayi Associated with TFs and helicases family protein 0.0013 0.000000000045487 0.000000000058772
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0128 0.1346 0.1723
Mycobacterium tuberculosis Probable lipase LipE 0.0042 0.0336 0.0415
Echinococcus granulosus Chromo domain 0.0013 0.000000000045487 0.000000000053597
Trichomonas vaginalis tubulin beta chain, putative 0.0144 0.1536 0.1985
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0674 0.774 1
Onchocerca volvulus 0.0162 0.1737 0.2244
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0068 0.0637 0.0805
Echinococcus multilocularis isocitrate dehydrogenase 0.0033 0.0229 0.0229
Loa Loa (eye worm) hypothetical protein 0.0042 0.0336 0.0434
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0013 0.000000000045487 0.000000000053597
Loa Loa (eye worm) thioredoxin reductase 0.0051 0.0437 0.0564
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0084 0.01
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0148 0.0192
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0715 0.0906
Onchocerca volvulus 0.0057 0.0509 0.0658
Plasmodium vivax DNA polymerase delta catalytic subunit, putative 0.0015 0.0022 0.0028
Schistosoma mansoni DNA polymerase alpha catalytic subunit 0.0055 0.0487 0.0574
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0073 0.0094
Leishmania major cathepsin L-like protease 0.002 0.0073 0.0075
Loa Loa (eye worm) ctsf protein 0.002 0.0073 0.0094
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0015 0.0025 0.0032
Brugia malayi hypothetical protein 0.0027 0.016 0.0207
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.005 0.0044
Mycobacterium leprae Probable lipase LipE 0.0042 0.0336 0.2407
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0084 0.0084
Onchocerca volvulus 0.0165 0.1773 0.2291
Loa Loa (eye worm) hypothetical protein 0.0162 0.1737 0.2244
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0715 0.0906
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0674 0.774 1
Onchocerca volvulus 0.0097 0.0979 0.1265
Toxoplasma gondii cytochrome p450 superfamily protein 0.0015 0.0015 0.002
Brugia malayi Isocitrate dehydrogenase 0.0033 0.0229 0.0296
Echinococcus multilocularis neurogenic locus notch protein 0.0026 0.0146 0.0146
Brugia malayi Latrophilin receptor protein 2 0.0033 0.0229 0.0296
Echinococcus granulosus DNA polymerase delta catalytic subunit 0.0015 0.0022 0.0026
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0212 0.0274
Brugia malayi Heterochromatin protein 1 0.0081 0.0795 0.1027
Schistosoma mansoni tubulin subunit beta 0.0165 0.1775 0.2091
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0052 0.0448 0.0579
Echinococcus multilocularis Ankyrin 0.0016 0.0026 0.0026
Trichomonas vaginalis penicillin-binding protein, putative 0.0042 0.0336 0.0434
Leishmania major alpha tubulin 0.0144 0.1536 0.1969
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0229 0.0277
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0177 0.0229
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.002 0.0078 0.0081
Trypanosoma brucei alpha tubulin 0.0144 0.1536 0.1969
Echinococcus multilocularis chromobox protein 1 0.0081 0.0795 0.0795
Echinococcus granulosus enteropeptidase 0.0165 0.1773 0.2089
Toxoplasma gondii thioredoxin reductase 0.0051 0.0437 0.0564
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0073 0.0094
Toxoplasma gondii alpha-tubulin I, putative 0.0144 0.1536 0.1985
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0048 0.0407 0.0526
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0042 0.0336 0.0395
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0325 0.042
Brugia malayi Cathepsin L-like precursor 0.002 0.0073 0.0094
Echinococcus multilocularis tubulin alpha chain 0.0144 0.1536 0.1536
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0084 0.01
Echinococcus granulosus thioredoxin glutathione reductase 0.0051 0.0437 0.0514
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0033 0.0229 0.0277
Onchocerca volvulus Cathepsin L homolog 0.002 0.0073 0.0094
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0033 0.0043
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0128 0.1346 0.1723
Echinococcus multilocularis DNA polymerase zeta catalytic subunit 0.0015 0.0022 0.0022
Trypanosoma brucei DNA polymerase epsilon catalytic subunit, putative 0.0015 0.0022 0.0009
Trichomonas vaginalis phosphofructokinase, putative 0.0116 0.1206 0.1558
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0336 0.0434
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0052 0.0448 0.0579
Schistosoma mansoni DNA polymerase delta catalytic subunit 0.0015 0.0022 0.0026
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0024 0.012 0.0594
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0084 0.0109
Brugia malayi Cathepsin L-like precursor 0.002 0.0073 0.0094
Brugia malayi Cathepsin L-like precursor 0.002 0.0073 0.0094
Brugia malayi TAR-binding protein 0.0132 0.1388 0.1794
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0263 0.034
Leishmania major alpha tubulin 0.0144 0.1536 0.1969
Echinococcus multilocularis Tubulin alpha 1 chain 0.0144 0.1536 0.1536
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0018 0.005 0.0044
Loa Loa (eye worm) hypothetical protein 0.0499 0.5682 0.7342
Loa Loa (eye worm) CHromoDomain protein family member 0.0015 0.0021 0.0026
Onchocerca volvulus Huntingtin homolog 0.0143 0.1516 0.1959
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0165 0.0165
Mycobacterium tuberculosis Conserved protein 0.0042 0.0336 0.0415
Schistosoma mansoni cercarial elastase (S01 family) 0.0165 0.1773 0.2089
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0048 0.0407 0.0507
Trypanosoma cruzi zeta tubulin, putative 0.0052 0.0448 0.0561
Echinococcus multilocularis musashi 0.0057 0.0509 0.0509
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0048 0.0407 0.0526
Loa Loa (eye worm) hypothetical protein 0.0018 0.0058 0.0074
Leishmania major cathepsin L-like protease 0.002 0.0073 0.0075
Toxoplasma gondii beta tubulin 0.0165 0.1775 0.2293
Echinococcus granulosus cathepsin l1 0.002 0.0073 0.0086
Leishmania major alpha tubulin 0.0144 0.1536 0.1969
Schistosoma mansoni cercarial elastase (S01 family) 0.0165 0.1773 0.2089
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0212 0.0247
Leishmania major ATP-dependent phosphofructokinase 0.0116 0.1206 0.1541
Schistosoma mansoni lozenge 0.0063 0.0577 0.068
Loa Loa (eye worm) hypothetical protein 0.0165 0.1773 0.2291
Onchocerca volvulus 0.0053 0.0464 0.0599
Brugia malayi Cell division protein ftsZ 0.0052 0.0448 0.0579
Echinococcus granulosus dna polymerase epsilon catalytic subunit a 0.0015 0.0022 0.0026
Brugia malayi EGF-like domain containing protein 0.0026 0.0146 0.0188
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0084 0.0109
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0116 0.1206 0.1541
Trichomonas vaginalis phosphofructokinase, putative 0.0116 0.1206 0.1558
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0229 0.0229
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.005 0.0044
Plasmodium vivax tubulin beta chain, putative 0.0165 0.1775 0.2293
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0074 0.0715 0.0906
Leishmania major trypanothione reductase 0.0051 0.0437 0.0545
Echinococcus multilocularis Tubulin beta 2C chain 0.0165 0.1775 0.1775
Schistosoma mansoni tar DNA-binding protein 0.0132 0.1388 0.1636
Mycobacterium ulcerans lipase LipD 0.0042 0.0336 0.1823
Trypanosoma brucei DNA polymerase delta catalytic subunit, putative 0.0015 0.0022 0.0009
Leishmania major beta tubulin 0.0165 0.1775 0.2278
Leishmania major alpha tubulin 0.0144 0.1536 0.1969
Plasmodium falciparum alpha tubulin 1 0.0144 0.1536 0.1985
Echinococcus multilocularis beta LACTamase domain containing family member 0.0042 0.0336 0.0336
Plasmodium falciparum cysteine proteinase falcipain 2a 0.002 0.0073 0.0094
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0222 0.0287
Entamoeba histolytica DNA polymerase alpha catalytic subunit, putative 0.0016 0.0026 0.0034
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0229 0.0229
Echinococcus granulosus beta tubulin 0.0165 0.1775 0.2091
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0018 0.005 0.0058
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0031 0.0212 0.0211
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0069 0.0653 0.0769
Trypanosoma brucei zeta tubulin, putative 0.0052 0.0448 0.0561
Schistosoma mansoni cpg binding protein 0.0032 0.0225 0.0265
Schistosoma mansoni cpg binding protein 0.0032 0.0225 0.0265
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0165 0.1773 0.2089
Trichomonas vaginalis DNA polymerase alpha catalytic subunit, putative 0.0015 0.0022 0.0028
Trypanosoma brucei beta tubulin 0.0165 0.1775 0.2278
Echinococcus granulosus cpg binding protein 0.0032 0.0225 0.0265
Trypanosoma cruzi cysteine peptidase, putative 0.002 0.0073 0.0075
Onchocerca volvulus 0.0042 0.0336 0.0434
Giardia lamblia Beta tubulin 0.0165 0.1775 0.2271
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0016 0.0033 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0177 0.0229
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0038 0.0293 0.0359
Schistosoma mansoni tar DNA-binding protein 0.0132 0.1388 0.1636
Brugia malayi RNA binding protein 0.0132 0.1388 0.1794
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0073 0.0094
Mycobacterium tuberculosis Probable lipase LipD 0.0042 0.0336 0.0415
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0292 0.0377
Loa Loa (eye worm) hypothetical protein 0.0165 0.1773 0.2291
Echinococcus multilocularis tubulin delta chain 0.0052 0.0448 0.0448
Trypanosoma cruzi zeta tubulin, putative 0.0052 0.0448 0.0561
Leishmania major hypothetical protein, conserved 0.0027 0.016 0.0187
Loa Loa (eye worm) CYP4Cod1 0.0024 0.012 0.0155
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0212 0.0274
Leishmania major delta tubulin, putative 0.0052 0.0448 0.0561
Schistosoma mansoni tubulin subunit delta 0.0052 0.0448 0.0528
Brugia malayi Thioredoxin reductase 0.0051 0.0437 0.0564
Echinococcus granulosus tubulin alpha chain 0.0144 0.1536 0.181
Loa Loa (eye worm) hypothetical protein 0.0042 0.0336 0.0434
Entamoeba histolytica hypothetical protein 0.0021 0.0084 0.0109
Brugia malayi regulator of G-protein signaling egl-10 0.0021 0.0084 0.0109
Echinococcus granulosus DNA polymerase alpha catalytic subunit 0.0055 0.0487 0.0574
Echinococcus multilocularis Chromobox protein 3 0.0013 0.00000004398 0.00000004398
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0116 0.1206 0.1541
Brugia malayi alpha-tubulin 0.0144 0.1536 0.1985
Loa Loa (eye worm) hypothetical protein 0.0093 0.0932 0.1204
Loa Loa (eye worm) hypothetical protein 0.0165 0.1773 0.2291
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.0555 0.0717
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0027 0.0163 0.0843
Loa Loa (eye worm) hypothetical protein 0.0026 0.0153 0.0198
Echinococcus multilocularis L aminoadipate semialdehyde 0.0097 0.0979 0.0979
Echinococcus multilocularis tubulin alpha 1C chain 0.0144 0.1536 0.1536
Brugia malayi CHD4 protein 0.0015 0.0021 0.0026
Echinococcus granulosus neuropeptide s receptor 0.0539 0.6154 0.7251
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0212 0.0274
Loa Loa (eye worm) hypothetical protein 0.0069 0.0653 0.0844
Echinococcus multilocularis 0.0015 0.0015 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0148 0.0192
Echinococcus granulosus cathepsin L cysteine proteinase 0.002 0.0073 0.0086
Schistosoma mansoni hypothetical protein 0.0033 0.0229 0.027
Echinococcus granulosus histone lysine methyltransferase setb 0.0069 0.0653 0.0769
Trichomonas vaginalis esterase, putative 0.0042 0.0336 0.0434
Brugia malayi Pre-SET motif family protein 0.0069 0.0653 0.0844
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0148 0.0191
Echinococcus multilocularis tubulin alpha 0.0119 0.1235 0.1235
Echinococcus granulosus glycoprotein Antigen 5 0.0165 0.1773 0.2089
Trichomonas vaginalis mercuric reductase, putative 0.0018 0.005 0.0064
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0084 0.0084
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.000000000045487 0.000000000058772
Schistosoma mansoni alpha tubulin 0.0144 0.1536 0.181
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0033 0.0023
Schistosoma mansoni hypothetical protein 0.0056 0.0502 0.0592
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0018 0.005 0.0058
Toxoplasma gondii DNA polymerase 0.0015 0.0022 0.0028
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0073 0.0094
Loa Loa (eye worm) hypothetical protein 0.0042 0.0336 0.0434
Leishmania major cathepsin L-like protease 0.002 0.0073 0.0075
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0042 0.0336 0.0415
Leishmania major DNA polymerase I alpha catalytic subunit, putative 0.0024 0.0125 0.0142
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0024 0.0029
Trypanosoma cruzi epsilon tubulin, putative 0.0119 0.1235 0.158
Mycobacterium tuberculosis Probable oxidoreductase 0.0128 0.1346 0.1723
Schistosoma mansoni DNA polymerase epsilon catalytic subunit 0.0015 0.0022 0.0026
Schistosoma mansoni hypothetical protein 0.0082 0.0809 0.0954
Trypanosoma brucei tubulin delta chain 0.0052 0.0448 0.0561
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0115 0.1195 0.1528
Echinococcus multilocularis Mastin 0.0165 0.1773 0.1773
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0674 0.774 0.774
Trichomonas vaginalis tubulin, putative 0.0067 0.0631 0.0816
Schistosoma mansoni cercarial elastase (S01 family) 0.0165 0.1773 0.2089
Echinococcus multilocularis cpg binding protein 0.0032 0.0225 0.0225
Schistosoma mansoni chondroitin sulfate proteoglycan-related 0.0026 0.0146 0.0172
Echinococcus multilocularis regulator of G protein signaling 0.0021 0.0084 0.0084
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0084 0.01
Trichomonas vaginalis tubulin, putative 0.0052 0.0448 0.0579
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0027 0.0163 0.2855
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0073 0.0094
Brugia malayi Tubulin beta chain 0.0052 0.0448 0.0579
Trichomonas vaginalis tubulin alpha chain, putative 0.0165 0.1775 0.2293
Loa Loa (eye worm) tubulin alpha 2 0.0093 0.0932 0.1204
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0068 0.0637 0.0824
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.0674 0.774 1
Loa Loa (eye worm) tubulin alpha chain 0.0144 0.1536 0.1985
Brugia malayi Cathepsin L-like precursor 0.002 0.0073 0.0094
Echinococcus granulosus intermediate filament protein 0.0057 0.0509 0.06
Giardia lamblia Delta tubulin 0.0052 0.0448 0.0553
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0018 0.005 0.0065
Loa Loa (eye worm) tubulin beta-1 chain 0.0165 0.1775 0.2293
Schistosoma mansoni tubulin subunit alpha 0.0052 0.0448 0.0528
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0104 0.1059 0.1369
Loa Loa (eye worm) isocitrate dehydrogenase 0.0033 0.0229 0.0296
Loa Loa (eye worm) tubulin beta chain 0.0052 0.0448 0.0579
Schistosoma mansoni tubulin subunit beta 0.0052 0.0448 0.0528
Echinococcus multilocularis Tubulin beta 2C chain 0.0165 0.1775 0.1775
Trichomonas vaginalis tubulin, putative 0.0067 0.0631 0.0816
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0377 0.0487
Leishmania major DNA polymerase delta catalytic subunit, putative 0.0015 0.0022 0.0009
Brugia malayi DNA polymerase delta catalytic subunit 0.0015 0.0022 0.0028
Brugia malayi DNA polymerase family B containing protein 0.0015 0.0022 0.0028
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0024 0.0029
Loa Loa (eye worm) hypothetical protein 0.0027 0.0165 0.0213
Leishmania major alpha tubulin 0.0144 0.1536 0.1969
Loa Loa (eye worm) hypothetical protein 0.0104 0.1059 0.1369
Schistosoma mansoni tubulin subunit beta 0.0165 0.1775 0.2091
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0081 0.0105
Loa Loa (eye worm) tubulin alpha chain 0.0144 0.1536 0.1985
Trypanosoma brucei epsilon tubulin 0.0119 0.1235 0.158
Echinococcus multilocularis GPCR, family 2 0.0033 0.0229 0.0229
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0069 0.0653 0.0653
Entamoeba histolytica phosphofructokinase, putative 0.0116 0.1206 0.1558
Echinococcus multilocularis Tubulin alpha 1 chain 0.0144 0.1536 0.1536
Loa Loa (eye worm) phosphofructokinase 0.0116 0.1206 0.1558
Loa Loa (eye worm) hypothetical protein 0.0026 0.0153 0.0198
Leishmania major beta tubulin 0.0165 0.1775 0.2278
Plasmodium vivax vivapain-2 0.002 0.0073 0.0094
Leishmania major beta tubulin 0.0165 0.1775 0.2278
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0084 0.01
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0674 0.774 1
Brugia malayi glutathione reductase 0.0051 0.0437 0.0564
Echinococcus multilocularis tissue type plasminogen activator 0.0018 0.005 0.005
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0212 0.0274
Echinococcus granulosus Tubulin beta 2C chain 0.0165 0.1775 0.2091
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0018 0.005 0.0064
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0292 0.0377
Plasmodium vivax tubulin gamma chain, putative 0.0119 0.1235 0.1596
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0165 0.1773 0.1773
Brugia malayi Trypsin family protein 0.0165 0.1773 0.2291
Trypanosoma brucei hypothetical protein, conserved 0.0027 0.0163 0.0192
Brugia malayi Death domain containing protein 0.0015 0.0024 0.0032
Schistosoma mansoni cercarial elastase (S01 family) 0.0165 0.1773 0.2089
Echinococcus multilocularis tubulin alpha chain 0.0144 0.1536 0.1536
Onchocerca volvulus 0.0042 0.0336 0.0434
Trypanosoma cruzi DNA polymerase epsilon catalytic subunit, putative 0.0015 0.0022 0.0009
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.016 0.0207
Onchocerca volvulus 0.0165 0.1773 0.2291
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0018 0.005 0.0195
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0038 0.0049
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0016 0.0026 0.0031
Echinococcus granulosus Tubulin alpha 1 chain 0.0144 0.1536 0.181
Brugia malayi PXA domain containing protein 0.0021 0.0084 0.0109
Schistosoma mansoni hypothetical protein 0.0018 0.005 0.0059
Brugia malayi CXXC zinc finger family protein 0.0031 0.0204 0.0264
Trypanosoma cruzi epsilon tubulin, putative 0.0119 0.1235 0.158
Loa Loa (eye worm) tubulin beta-2A chain 0.0165 0.1775 0.2293
Brugia malayi intermediate filament protein 0.0057 0.0509 0.0658
Echinococcus multilocularis Tubulin beta 2C chain 0.0165 0.1775 0.1775
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0052 0.0448 0.0579
Echinococcus multilocularis tubulin beta 1 chain 0.0165 0.1775 0.1775
Echinococcus granulosus tubulin alpha chain 0.0144 0.1536 0.181
Loa Loa (eye worm) RNA binding protein 0.0132 0.1388 0.1794
Schistosoma mansoni tar DNA-binding protein 0.0132 0.1388 0.1636
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.012 0.0155
Echinococcus granulosus DNA polymerase zeta catalytic subunit 0.0015 0.0022 0.0026
Echinococcus granulosus beta tubulin 0.0165 0.1775 0.2091
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0222 0.0286
Brugia malayi chromobox protein homolog 3 0.0046 0.0377 0.0487
Schistosoma mansoni tubulin subunit beta 0.0165 0.1775 0.2091
Brugia malayi Pre-SET motif family protein 0.0477 0.5435 0.7022
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0082 0.0809 0.0954
Schistosoma mansoni cercarial elastase (S01 family) 0.0165 0.1773 0.2089
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0674 0.774 1
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0013 0.000000000045487 0.000000000058772
Plasmodium vivax DNA polymerase epsilon, catalytic subunit a, putative 0.0015 0.0022 0.0028
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0084 0.0084
Brugia malayi Trypsin-like protease protein 5 0.0165 0.1773 0.2291
Trichomonas vaginalis tubulin alpha chain, putative 0.0067 0.0631 0.0816
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0015 0.0021 0.0024
Echinococcus multilocularis beta adrenergic receptor kinase 0.0021 0.0084 0.0084
Mycobacterium tuberculosis Conserved protein 0.0042 0.0336 0.0415
Loa Loa (eye worm) hypothetical protein 0.0674 0.774 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.005 0.0044
Brugia malayi MH2 domain containing protein 0.0134 0.1418 0.1832
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0073 0.0086
Echinococcus multilocularis bloom syndrome protein 0.0023 0.0112 0.0112
Trichomonas vaginalis tubulin beta chain, putative 0.0144 0.1536 0.1985
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0112 0.0144
Schistosoma mansoni transcription factor LCR-F1 0.0082 0.0809 0.0954
Trichomonas vaginalis tubulin epsilon chain, putative 0.0165 0.1775 0.2293
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0018 0.005 0.005
Brugia malayi hypothetical protein 0.0082 0.0809 0.1046
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0027 0.0163 0.0211
Leishmania major beta tubulin 0.0165 0.1775 0.2278
Brugia malayi hypothetical protein 0.0162 0.1737 0.2244
Loa Loa (eye worm) hypothetical protein 0.0018 0.005 0.0065
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0407 0.0526
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0048 0.0407 0.0507
Echinococcus granulosus geminin 0.0388 0.439 0.5172
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0073 0.0094
Loa Loa (eye worm) PXA domain-containing protein 0.0021 0.0084 0.0109
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.016 0.0207
Leishmania major eukaryotic initiation factor 4a, putative 0.0674 0.774 1
Brugia malayi PXA domain containing protein 0.0021 0.0084 0.0109
Schistosoma mansoni alpha tubulin 0.0144 0.1536 0.181
Leishmania major phosphatidylinositol 3-kinase, putative 0.0016 0.0033 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0263 0.034
Schistosoma mansoni tubulin subunit gamma 0.0119 0.1235 0.1456
Plasmodium vivax tubulin alpha chain, putative 0.0144 0.1536 0.1985
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0084 0.01
Leishmania major cathepsin L-like protease 0.002 0.0073 0.0075
Loa Loa (eye worm) cysteine protease 0.002 0.0073 0.0094
Brugia malayi Cytochrome P450 family protein 0.0015 0.0015 0.002
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.016 0.0187
Onchocerca volvulus 0.002 0.0073 0.0094
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0073 0.0094
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0082 0.0809 0.0953
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0042 0.0336 0.0415
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0073 0.0094
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0024 0.0032
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0084 0.01
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0115 0.1195 0.1528
Echinococcus granulosus 6 phosphofructokinase 0.0116 0.1206 0.1421
Loa Loa (eye worm) transcription factor SMAD2 0.0134 0.1418 0.1832
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0181 0.0234
Treponema pallidum cell division protein FtsZ 0.0052 0.0448 0.0518
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0033 0.0229 0.027
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0048 0.0407 0.0507
Brugia malayi Papain family cysteine protease containing protein 0.002 0.0073 0.0094
Onchocerca volvulus 0.002 0.0073 0.0094
Leishmania major alpha tubulin 0.0144 0.1536 0.1969
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0336 0.0415
Schistosoma mansoni tubulin subunit alpha 0.0144 0.1536 0.181
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0084 0.01
Entamoeba histolytica hypothetical protein 0.0082 0.0809 0.1046
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.005 0.0044
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0212 0.0274
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0093 0.0932 0.1204
Loa Loa (eye worm) RecQ helicase 0.0023 0.0112 0.0144
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0084 0.01
Trichomonas vaginalis tubulin gamma chain, putative 0.0052 0.0448 0.0579
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0073 0.0094
Trypanosoma cruzi DNA polymerase I alpha catalytic subunit, putative 0.0024 0.0125 0.0142
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0165 0.1773 0.2089
Brugia malayi Uncoordinated protein 44 0.0015 0.0024 0.0032
Echinococcus granulosus tubulin subunit beta 0.0165 0.1775 0.2091
Plasmodium vivax tubulin alpha chain, putative 0.0144 0.1536 0.1985
Echinococcus multilocularis DNA polymerase alpha catalytic subunit 0.0055 0.0487 0.0487
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0055 0.0493 0.0637
Echinococcus multilocularis neuropeptide s receptor 0.0539 0.6154 0.6154
Echinococcus multilocularis tubulin epsilon chain 0.0119 0.1235 0.1235
Echinococcus multilocularis expressed protein 0.0399 0.4519 0.4519
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0084 0.01
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0033 0.0229 0.0296
Schistosoma mansoni hypothetical protein 0.0033 0.0229 0.027
Leishmania major cathepsin L-like protease 0.0074 0.0715 0.0906
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0128 0.1346 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0229 0.0229
Onchocerca volvulus 0.0165 0.1773 0.2291
Schistosoma mansoni alpha tubulin 0.0144 0.1536 0.181
Echinococcus multilocularis 6 phosphofructokinase 0.0116 0.1206 0.1206
Loa Loa (eye worm) hypothetical protein 0.0143 0.1516 0.1959
Leishmania major beta tubulin 0.0165 0.1775 0.2278
Trypanosoma cruzi cruzipain precursor, putative 0.0074 0.0715 0.0906
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0097 0.0979 0.1153
Echinococcus multilocularis tumor protein p63 0.0361 0.4076 0.4076
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0013 0.000000000045487 0.000000000053597
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0048 0.0407 0.048
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0165 0.1773 0.2089
Loa Loa (eye worm) TAR-binding protein 0.0132 0.1388 0.1794
Onchocerca volvulus DNA polymerase epsilon catalytic subunit A homolog 0.0015 0.0022 0.0028
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0116 0.1206 0.1503
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0097 0.0979 0.1265
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0165 0.1773 0.2089
Treponema pallidum ATP-dependent RNA helicase 0.0674 0.774 1
Echinococcus multilocularis hypothetical protein 0.0144 0.1536 0.1536
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0674 0.774 0.912
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0027 0.0163 0.0192
Schistosoma mansoni hypothetical protein 0.0388 0.439 0.5172

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) < 5 % Inhibitory activity against 3'-processing by HIV-1 Integrase at 100 microM ChEMBL. 8568830
Inhibition (binding) < 5 % Inhibitory activity against strand transfer by HIV-1 Integrase at 100 microM ChEMBL. 8568830
Inhibition (binding) < 5 % Inhibitory activity against 3'-processing by HIV-1 Integrase at 100 microM ChEMBL. 8568830
Inhibition (binding) < 5 % Inhibitory activity against strand transfer by HIV-1 Integrase at 100 microM ChEMBL. 8568830

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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