Detailed information for compound 311895

Basic information

Technical information
  • TDR Targets ID: 311895
  • Name: 1-(6-bromo-2,2-dimethyl-3,4-dihydrochromen-4- yl)-3-propan-2-ylthiourea
  • MW: 357.309 | Formula: C15H21BrN2OS
  • H donors: 2 H acceptors: 0 LogP: 3.71 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(NC(=S)NC1CC(C)(C)Oc2c1cc(Br)cc2)C
  • InChi: 1S/C15H21BrN2OS/c1-9(2)17-14(20)18-12-8-15(3,4)19-13-6-5-10(16)7-11(12)13/h5-7,9,12H,8H2,1-4H3,(H2,17,18,20)
  • InChiKey: QISMDQOOEJBZPX-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 1-(6-bromo-2,2-dimethyl-chroman-4-yl)-3-isopropyl-thiourea
  • 1-(6-bromo-2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-4-yl)-3-isopropylthiourea
  • 1-(6-bromo-2,2-dimethyl-3,4-dihydrochromen-4-yl)-3-propan-2-yl-thiourea
  • 1-(6-bromo-2,2-dimethylchroman-4-yl)-3-propan-2-ylthiourea
  • 1-(6-bromo-2,2-dimethyl-4-chromanyl)-3-isopropylthiourea
  • 1-(6-bromo-2,2-dimethyl-chroman-4-yl)-3-propan-2-yl-thiourea

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.0236 0.0261
Echinococcus granulosus microtubule associated protein 2 0.1483 0.8499 1
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0352 0.1962 0.7002
Brugia malayi G protein-coupled receptor 0.0054 0.0236 0.0437
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0123 0.0638 0.0734
Loa Loa (eye worm) hypothetical protein 0.0044 0.0181 0.0322
Mycobacterium ulcerans oxygenase 0.0024 0.0064 0.0104
Loa Loa (eye worm) hypothetical protein 0.0021 0.0044 0.0058
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0054 0.0236 0.0429
Treponema pallidum sodium- and chloride- dependent transporter 0.0261 0.1432 1
Echinococcus granulosus dna polymerase eta 0.0021 0.0044 0.0035
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0115 0.059 0.1114
Onchocerca volvulus 0.0054 0.0236 0.0429
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0006 0.0013
Echinococcus multilocularis transcription factor Dp 1 0.0041 0.0163 0.0149
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0041 0.016 0.0145
Mycobacterium ulcerans flavodoxin reductase Hmp 0.0024 0.0064 0.0104
Trichomonas vaginalis Ferredoxin 3 0.0024 0.0064 0.015
Loa Loa (eye worm) cytochrome P450 family protein 0.0038 0.0144 0.0251
Echinococcus granulosus lipoxygenase domain containing protein 0.0042 0.0169 0.0182
Trichomonas vaginalis Ferredoxin 2 0.0024 0.0064 0.015
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0006 0.0013
Brugia malayi Serotonin receptor 0.055 0.3103 0.5984
Echinococcus multilocularis acetylcholinesterase 0.0073 0.0347 0.0333
Schistosoma mansoni biogenic amine receptor 0.0054 0.0236 0.0261
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0019 0.0035 0.0064
Echinococcus granulosus allatostatin A receptor 0.0054 0.0236 0.0261
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0019 0.0044
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0071 0.0336 0.0379
Plasmodium vivax octaprenyl pyrophosphate synthase, putative 0.0028 0.0086 0.1172
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0185 0.0997 0.0984
Onchocerca volvulus 0.0054 0.0236 0.0429
Brugia malayi hypothetical protein 0.048 0.2701 0.5205
Mycobacterium leprae conserved hypothetical protein 0.0022 0.005 0.0402
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0076 0.0179
Onchocerca volvulus 0.0054 0.0236 0.0429
Brugia malayi Dopamine receptor 0.0054 0.0236 0.0437
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0041 0.0161 0.2556
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0123 0.0638 0.219
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0909 0.518 1
Onchocerca volvulus 0.0108 0.0552 0.1041
Onchocerca volvulus Glucosylceramidase homolog 0.0364 0.203 0.3903
Leishmania major cytochrome p450-like protein 0.0038 0.0144 0.0278
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0909 0.518 0.6088
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0044 0.0082
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0023 0.0057 0.0111
Brugia malayi Intermediate filament tail domain containing protein 0.0058 0.026 0.0483
Schistosoma mansoni nuclear hormone receptor 0.0429 0.2404 0.2816
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0041 0.016 0.0145
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0014 0.000000027476
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0023 0.0016
Schistosoma mansoni biogenic amine receptor 0.0054 0.0236 0.0261
Trypanosoma cruzi Emopamil binding protein, putative 0.0148 0.0782 0.1698
Brugia malayi beta-lactamase family protein 0.0039 0.0148 0.0266
Loa Loa (eye worm) hypothetical protein 0.0909 0.518 1
Echinococcus multilocularis farnesyl pyrophosphate synthase 0.0111 0.0564 0.055
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0041 0.016 0.0145
Schistosoma mansoni myosin xvIII 0.0054 0.0236 0.0261
Onchocerca volvulus Adrenodoxin, mitochondrial homolog 0.0024 0.0064 0.0095
Brugia malayi hypothetical protein 0.0044 0.0181 0.033
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0148 0.0157
Schistosoma mansoni polycystin 1-related 0.0042 0.0169 0.0182
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0555 0.3134 0.6042
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0054 0.0236 0.0261
Loa Loa (eye worm) hypothetical protein 0.0093 0.0463 0.0869
Toxoplasma gondii target of rapamycin (TOR), putative 0.0036 0.0133 0.1683
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0041 0.016 0.0145
Echinococcus granulosus orexin receptor type 2 0.0054 0.0236 0.0261
Entamoeba histolytica hypothetical protein 0.0039 0.0148 0.198
Leishmania major DNA polymerase eta, putative 0.0021 0.0044 0.0057
Chlamydia trachomatis endonuclease IV 0.0082 0.0399 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0119 0.0202
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0044 0.0058
Trypanosoma brucei cardiolipin synthetase, putative 0.0039 0.0148 0.0313
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0044 0.0082
Loa Loa (eye worm) hypothetical protein 0.0909 0.518 1
Mycobacterium ulcerans polyprenyl diphosphate synthetase, GrcC1 0.0028 0.0086 0.0186
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0138 0.0326
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0044 0.0066
Plasmodium vivax SET domain protein, putative 0.0034 0.0119 0.1774
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0006 0.0013
Brugia malayi nuclear receptor NHR-88 0.0429 0.2404 0.463
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Onchocerca volvulus 0.0474 0.2667 0.5136
Plasmodium falciparum mitochondrial cardiolipin synthase, putative 0.0018 0.0027 0.0089
Onchocerca volvulus 0.0054 0.0236 0.0429
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0022 0.005 0.0077
Onchocerca volvulus Putative phospholipase D 0.0021 0.0046 0.0061
Schistosoma mansoni hypothetical protein 0.0056 0.0247 0.0274
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0016 0.0016 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0044 0.0082
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0148 0.0782 0.1698
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0019 0.0035 0.0062
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Schistosoma mansoni aldehyde dehydrogenase 0.013 0.0679 0.0784
Leishmania major polyprenyl synthase, putative 0.0028 0.0086 0.015
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0044 0.0181 0.033
Schistosoma mansoni lipoxygenase 0.0109 0.0557 0.064
Loa Loa (eye worm) hypothetical protein 0.0042 0.0169 0.0299
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0054 0.0236 0.0222
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0054 0.0236 0.0261
Giardia lamblia [2Fe-2S] ferredoxin 0.0024 0.0064 0.0373
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0041 0.016 0.0145
Brugia malayi steroid hormone receptor 0.0909 0.518 1
Trypanosoma brucei C-8 sterol isomerase, putative 0.0794 0.4515 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0119 0.0123
Loa Loa (eye worm) hypothetical protein 0.0039 0.0148 0.0258
Loa Loa (eye worm) hypothetical protein 0.0039 0.0148 0.0258
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Trichomonas vaginalis geranylgeranyl diphosphate synthase, putative 0.0111 0.0564 0.1329
Echinococcus granulosus phospholipase D1 0.0111 0.0566 0.065
Mycobacterium tuberculosis Conserved protein 0.0039 0.0148 0.0645
Brugia malayi Phospholipase d protein 1 0.0111 0.0566 0.1075
Onchocerca volvulus 0.0054 0.0236 0.0429
Mycobacterium ulcerans beta-lactamase 0.0039 0.0148 0.041
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0082 0.0399 0.6959
Echinococcus granulosus Polycystic kidney disease protein 0.0042 0.0169 0.0182
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0039 0.0153 0.0164
Loa Loa (eye worm) hypothetical protein 0.0073 0.0347 0.0645
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0033 0.0078
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0043 0.0174 0.0188
Echinococcus multilocularis decaprenyl diphosphate synthase subunit 1 0.0028 0.0086 0.0072
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0041 0.016 0.0171
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0133 0.0314
Entamoeba histolytica geranylgeranyl pyrophosphate synthetase, putative 0.0028 0.0086 0.0802
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0148 0.0348
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0044 0.0082
Echinococcus multilocularis tyrosine protein kinase Srms 0.0037 0.0137 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0174 0.0409
Echinococcus multilocularis sex peptide receptor 0.0054 0.0236 0.0222
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0138 0.0326
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0148 0.0266
Loa Loa (eye worm) phosphatidylinositol 3 0.0048 0.0205 0.0369
Leishmania major hypothetical protein, conserved 0.0148 0.0782 0.1698
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0136 0.0243
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0092 0.0217
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0429 0.2404 0.2816
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0044 0.0112
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0091 0.0213
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.0236 0.0222
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0909 0.518 1
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0023 0.0008
Loa Loa (eye worm) hypothetical protein 0.0373 0.2079 0.3998
Echinococcus multilocularis neuropeptide Y receptor 0.0054 0.0236 0.0222
Onchocerca volvulus 0.0148 0.0782 0.1486
Echinococcus granulosus thyroid hormone receptor alpha 0.0429 0.2404 0.2816
Plasmodium vivax hypothetical protein, conserved 0.0044 0.0181 0.2919
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0048 0.0205 0.0439
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0119 0.0123
Brugia malayi Nuclear hormone receptor-like 1 0.0909 0.518 1
Echinococcus multilocularis allatostatin A receptor 0.0054 0.0236 0.0222
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0054 0.0236 0.0222
Loa Loa (eye worm) neuropeptide F receptor 0.0054 0.0236 0.0429
Onchocerca volvulus 0.0054 0.0236 0.0429
Trypanosoma cruzi polyprenyl synthase, putative 0.0028 0.0086 0.015
Brugia malayi hypothetical protein 0.0042 0.0169 0.0307
Echinococcus multilocularis ferredoxin adrenodoxin 0.0024 0.0064 0.0049
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0044 0.0082
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0041 0.0161 0.0316
Plasmodium vivax multidomain scavenger receptor, putative 0.0042 0.0169 0.2703
Schistosoma mansoni nuclear hormone receptor 0.0909 0.518 0.6088
Loa Loa (eye worm) 2Fe-2S iron-sulfur cluster binding domain-containing protein 0.0024 0.0064 0.0095
Echinococcus granulosus rhodopsin orphan GPCR 0.0054 0.0236 0.0261
Loa Loa (eye worm) cytochrome P450 0.0019 0.0035 0.004
Brugia malayi neuropeptide F receptor 0.0054 0.0236 0.0437
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0041 0.016 0.0145
Onchocerca volvulus 0.0054 0.0236 0.0429
Loa Loa (eye worm) beta-lactamase 0.0039 0.0148 0.0258
Brugia malayi nuclear receptor RXR 0.0429 0.2404 0.463
Loa Loa (eye worm) hypothetical protein 0.0043 0.0174 0.0309
Echinococcus granulosus neuropeptide Y receptor 0.0054 0.0236 0.0261
Treponema pallidum hypothetical protein 0.01 0.0503 0.3099
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0909 0.518 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0909 0.518 1
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0043 0.0174 0.0345
Plasmodium vivax cardiolipin synthetase, putative 0.0018 0.0027 0.0089
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0043 0.0174 0.0188
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.005 0.0139
Echinococcus multilocularis g protein coupled receptor 0.0054 0.0236 0.0222
Loa Loa (eye worm) hypothetical protein 0.0022 0.005 0.0068
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0076 0.018
Echinococcus granulosus tm gpcr rhodopsin 0.0054 0.0236 0.0261
Schistosoma mansoni adenoreceptor 0.0054 0.0236 0.0261
Brugia malayi GnHR receptor homolog 0.0054 0.0236 0.0437
Schistosoma mansoni retinoid-x-receptor (RXR) 0.048 0.2701 0.3166
Brugia malayi hypothetical protein 0.0474 0.2667 0.514
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0044 0.0082
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0022 0.005 0.0068
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.0236 0.0222
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0023 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0205 0.0483
Echinococcus granulosus neuropeptides capa receptor 0.0054 0.0236 0.0261
Loa Loa (eye worm) hypothetical protein 0.0429 0.2404 0.4626
Echinococcus granulosus geminin 0.0181 0.0974 0.1131
Echinococcus granulosus Adrenodoxin mitochondrial 0.0024 0.0064 0.0058
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0048 0.0205 0.0225
Loa Loa (eye worm) hypothetical protein 0.0108 0.0552 0.1041
Echinococcus granulosus lamin dm0 0.0058 0.026 0.0289
Brugia malayi AKH receptor 0.0054 0.0236 0.0437
Brugia malayi beta-lactamase family protein 0.0039 0.0148 0.0266
Onchocerca volvulus 0.0054 0.0236 0.0429
Onchocerca volvulus 0.0054 0.0236 0.0429
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0019 0.0044
Loa Loa (eye worm) hypothetical protein 0.0909 0.518 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0041 0.0161 0.2556
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0044 0.0104
Echinococcus multilocularis GPCR, family 2 0.0017 0.0023 0.0008
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0044 0.0181 0.0196
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Mycobacterium ulcerans aldehyde dehydrogenase 0.013 0.0679 0.2342
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0082 0.0399 0.6959
Echinococcus granulosus tyrosine protein kinase Src42A 0.0041 0.016 0.0171
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0044 0.0181 0.2407
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0019 0.0035 0.0064
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0373 0.2079 0.2434
Brugia malayi photoreceptor-specific nuclear receptor 0.0909 0.518 1
Schistosoma mansoni thyroid hormone receptor 0.0909 0.518 0.6088
Echinococcus granulosus FTZ F1 alpha 0.0909 0.518 0.6088
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0909 0.518 0.5173
Trypanosoma cruzi target of rapamycin kinase 3 0.0039 0.0148 0.0287
Loa Loa (eye worm) hypothetical protein 0.0429 0.2404 0.4626
Mycobacterium tuberculosis Conserved protein 0.0039 0.0148 0.0645
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0352 0.1962 0.7002
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Chlamydia trachomatis Na(+)-translocating NADH-quinone reductase subunit F 0.0024 0.0064 0.0974
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.002 0.0006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0909 0.518 1
Schistosoma mansoni lamin 0.0058 0.026 0.0289
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0148 0.0258
Brugia malayi tailless protein 0.0429 0.2404 0.463
Echinococcus granulosus prenyl decaprenyl diphosphate synthase 0.0028 0.0086 0.0084
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0043 0.0174 0.0317
Onchocerca volvulus 0.0046 0.0189 0.0339
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Onchocerca volvulus 0.0044 0.0181 0.0322
Schistosoma mansoni amine GPCR 0.0054 0.0236 0.0261
Echinococcus granulosus Nuclear hormone receptor HR96 0.0429 0.2404 0.2816
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0148 0.0157
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0019 0.0017
Echinococcus multilocularis prenyl (decaprenyl) diphosphate synthase 0.0028 0.0086 0.0072
Brugia malayi Protein K4 0.0018 0.0027 0.0034
Loa Loa (eye worm) hypothetical protein 0.0039 0.0148 0.0258
Schistosoma mansoni CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 0.0018 0.0027 0.0015
Brugia malayi protein-tyrosine kinase 0.0037 0.0137 0.0245
Schistosoma mansoni DNA polymerase eta 0.0021 0.0044 0.0035
Treponema pallidum quinoline 2-oxidoreductase 0.0119 0.0611 0.3898
Brugia malayi Death domain containing protein 0.0015 0.0014 0.0008
Plasmodium falciparum geranylgeranyl pyrophosphate synthase, putative 0.0111 0.0564 1
Loa Loa (eye worm) hypothetical protein 0.0474 0.2667 0.5136
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0174 0.0188
Loa Loa (eye worm) hypothetical protein 0.0057 0.0254 0.0463
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0054 0.0236 0.0261
Echinococcus granulosus dro:myosuppressin receptor 0.0054 0.0236 0.0261
Loa Loa (eye worm) DR-78 0.0429 0.2404 0.4626
Echinococcus multilocularis neuropeptide receptor 0.0054 0.0236 0.0222
Brugia malayi G-protein coupled receptor 0.0054 0.0236 0.0437
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0016 0.0019 0.0005
Onchocerca volvulus 0.0054 0.0236 0.0429
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0373 0.2079 0.4003
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0048 0.0205 0.0439
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0205 0.0483
Brugia malayi hypothetical protein 0.0054 0.0236 0.0437
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.014
Loa Loa (eye worm) neuropeptide F receptor 0.0054 0.0236 0.0429
Echinococcus granulosus tyrosine kinase 0.0037 0.0137 0.0144
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.0111 0.0564 0.1329
Echinococcus granulosus biogenic amine 5HT receptor 0.0054 0.0236 0.0261
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0014 0.000000023346
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0006 0.0013
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0226 0.123 0.2353
Echinococcus granulosus rhodopsin orphan GPCR 0.0054 0.0236 0.0261
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Trypanosoma cruzi farnesyl pyrophosphate synthase, putative 0.0111 0.0564 0.1213
Brugia malayi SRC-1 0.0041 0.016 0.0289
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0044 0.0181 0.033
Loa Loa (eye worm) hypothetical protein 0.0429 0.2404 0.4626
Trichomonas vaginalis glucosylceramidase, putative 0.0384 0.2144 0.5049
Loa Loa (eye worm) hypothetical protein 0.0261 0.1432 0.2744
Toxoplasma gondii adrenodoxin-type ferredoxin, putative 0.0024 0.0064 0.0625
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0023 0.0024
Echinococcus granulosus cytochrome P450 2K1 0.0019 0.0035 0.0024
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.0336 0.0706
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0555 0.3134 0.6039
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0909 0.518 0.6088
Loa Loa (eye worm) hypothetical protein 0.0261 0.1432 0.2744
Loa Loa (eye worm) hypothetical protein 0.0044 0.0181 0.0322
Plasmodium vivax ferredoxin, putative 0.0024 0.0064 0.0758
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0133 0.0314
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0046 0.0189 0.0206
Loa Loa (eye worm) phosphatidylinositol 3 0.0016 0.0019 0.0008
Loa Loa (eye worm) hypothetical protein 0.0036 0.0136 0.0235
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0041 0.0161 0.0316
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0148 0.0348
Schistosoma mansoni thyroid hormone receptor 0.0909 0.518 0.6088
Trichomonas vaginalis esterase, putative 0.0039 0.0148 0.0348
Schistosoma mansoni opsin-like receptor 0.0054 0.0236 0.0261
Brugia malayi hypothetical protein 0.0109 0.0553 0.105
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0909 0.518 1
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0006 0.0013
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0082 0.1095
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0352 0.1962 1
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.048 0.2701 0.5201
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0019 0.0035 0.0064
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0096 0.0481 0.055
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0143 0.075 0.2597
Giardia lamblia GTOR 0.0048 0.0205 0.3091
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0019 0.0035 0.0064
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0909 0.518 1
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0429 0.2404 0.2816
Trypanosoma cruzi Emopamil binding protein, putative 0.0148 0.0782 0.1698
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.0236 0.0261
Brugia malayi neuropeptide F receptor 0.0054 0.0236 0.0437
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0016 0.0016 0.0001
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0076 0.018
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0148 0.0645
Leishmania major DNA polymerase kappa, putative 0.0021 0.0044 0.0057
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0054 0.0236 0.0429
Echinococcus multilocularis nuclear receptor nhr 48 0.0429 0.2404 0.2393
Schistosoma mansoni nuclear receptor 0.0429 0.2404 0.2816
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.002 0.0007
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0054 0.0236 0.0222
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0041 0.0161 0.0316
Brugia malayi Polyprenyl synthetase family protein 0.0111 0.0564 0.1072
Loa Loa (eye worm) hypothetical protein 0.0018 0.0027 0.0025
Leishmania major solanesyl-diphosphate synthase, putative 0.0028 0.0086 0.015
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0148 0.041
Brugia malayi intermediate filament protein 0.0058 0.026 0.0483
Loa Loa (eye worm) steroid hormone receptor 0.0909 0.518 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0044 0.0057
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0148 0.3095
Leishmania major ferredoxin, 2fe-2s-like protein 0.0024 0.0064 0.01
Onchocerca volvulus 0.0054 0.0236 0.0429
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0082 0.0141
Trichomonas vaginalis glucosylceramidase, putative 0.0555 0.3134 0.7382
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0048 0.0205 0.3079
Schistosoma mansoni hypothetical protein 0.0054 0.0236 0.0261
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0076 0.0179
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0495 0.2787 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0076 0.018
Onchocerca volvulus 0.0039 0.0148 0.0258
Brugia malayi Cytochrome P450 family protein 0.0038 0.0144 0.0259
Echinococcus granulosus sodium and chloride dependent glycine 0.0044 0.0181 0.0196
Loa Loa (eye worm) norepinephrine transporter 0.0261 0.1432 0.2744
Trypanosoma cruzi cytochrome P450, putative 0.0038 0.0144 0.0278
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0257 0.1412 0.1647
Brugia malayi Melatonin receptor type 1A 0.0054 0.0236 0.0437
Entamoeba histolytica phospholipase D active site domain-containing protein 0.0093 0.0463 0.8032
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0041 0.0161 0.0292
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0041 0.0161 0.0379
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Mycobacterium tuberculosis Probable multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 (GGPP synthetase) (ggppsase) (geranylgeranyl diphosphate 0.0028 0.0086 0.0327
Loa Loa (eye worm) G-protein coupled receptor 0.0054 0.0236 0.0429
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0909 0.518 1
Echinococcus multilocularis orexin receptor type 2 0.0054 0.0236 0.0222
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0071 0.0336 0.0631
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.0111 0.0564 0.1923
Echinococcus multilocularis neuropeptide receptor 0.0054 0.0236 0.0222
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0023 0.001
Trichomonas vaginalis glucosylceramidase, putative 0.0384 0.2144 0.5049
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0044 0.0082
Echinococcus granulosus tyrosine protein kinase Blk 0.0037 0.0137 0.0144
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0261 0.1432 0.2751
Schistosoma mansoni hypothetical protein 0.0181 0.0974 0.1131
Leishmania major phosphatidylglycerophosphate synthase, putative 0.0021 0.0046 0.006
Echinococcus granulosus neuropeptide receptor 0.0054 0.0236 0.0261
Schistosoma mansoni cytochrome P450 0.0019 0.0035 0.0024
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.0236 0.0261
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.1414 0.8102 0.9532
Schistosoma mansoni opsin-like receptor 0.0054 0.0236 0.0261
Loa Loa (eye worm) hypothetical protein 0.0373 0.2079 0.3998
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0019 0.0035 0.0064
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0148 0.0348
Onchocerca volvulus 0.0054 0.0236 0.0429
Leishmania major farnesyl pyrophosphate synthase 0.0111 0.0564 0.1213
Brugia malayi Protein kinase domain containing protein 0.0015 0.0014 0.0008
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.002 0.0006
Onchocerca volvulus 0.0039 0.0148 0.0258
Brugia malayi hypothetical protein 0.0039 0.0148 0.0266
Loa Loa (eye worm) hypothetical protein 0.0044 0.0181 0.0322
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0048 0.0205 0.3079
Entamoeba histolytica geranylgeranyl pyrophosphate synthase, putative 0.0028 0.0086 0.0802
Echinococcus multilocularis musashi 0.0058 0.026 0.0246
Schistosoma mansoni hypothetical protein 0.0017 0.0023 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0909 0.518 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0076 0.018
Loa Loa (eye worm) hypothetical protein 0.0072 0.0342 0.0635
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0044 0.0181 0.0166
Schistosoma mansoni RAR-like nuclear receptor 0.0909 0.518 0.6088
Echinococcus granulosus hypothetical protein 0.0798 0.4537 0.5331
Loa Loa (eye worm) geranylgeranyl pyrophosphate synthetase 0.0028 0.0086 0.0139
Schistosoma mansoni steroid hormone receptor ad4bp 0.0909 0.518 0.6088
Echinococcus multilocularis tyrosine protein kinase HCK 0.0033 0.0113 0.0099
Mycobacterium ulcerans hypothetical protein 0.0022 0.005 0.0053
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0119 0.1463
Echinococcus multilocularis sodium and chloride dependent glycine 0.0044 0.0181 0.0166
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0133 0.0314
Trichomonas vaginalis glucosylceramidase, putative 0.0364 0.203 0.4782
Trichomonas vaginalis glucosylceramidase, putative 0.0555 0.3134 0.7382
Brugia malayi hypothetical protein 0.0018 0.0026 0.0031
Onchocerca volvulus 0.0054 0.0236 0.0429
Brugia malayi nuclear hormone receptor family member odr-7 0.0429 0.2404 0.463
Echinococcus granulosus lipoxygenase domain containing protein 0.0042 0.0169 0.0182
Echinococcus granulosus g protein coupled receptor 0.0054 0.0236 0.0261
Onchocerca volvulus 0.0039 0.0148 0.0258
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0054 0.0236 0.0429
Loa Loa (eye worm) nuclear hormone receptor 0.0429 0.2404 0.4626
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0082 0.0399 0.1943
Echinococcus multilocularis RUN 0.0042 0.0169 0.0155
Loa Loa (eye worm) hypothetical protein 0.0909 0.518 1
Toxoplasma gondii aldehyde dehydrogenase 0.013 0.0679 1
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0185 0.0997 0.1158
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0043 0.0174 0.037
Loa Loa (eye worm) hypothetical protein 0.0073 0.0347 0.0645
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0019 0.0035 0.0064
Brugia malayi nuclear receptor RXR 0.048 0.2701 0.5205
Schistosoma mansoni cpg binding protein 0.0065 0.0302 0.0339
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0429 0.2404 0.2816
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0909 0.518 0.5173
Schistosoma mansoni neuropeptide receptor 0.0054 0.0236 0.0261
Loa Loa (eye worm) hypothetical protein 0.0109 0.0553 0.1042
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0024 0.0064 0.01
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.013 0.0679 0.0666
Schistosoma mansoni biogenic amine (5HT) receptor 0.0054 0.0236 0.0261
Onchocerca volvulus Bile acid receptor homolog 0.0909 0.518 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Mycobacterium ulcerans lipase LipD 0.0039 0.0148 0.041
Schistosoma mansoni rab6-interacting 0.0042 0.0169 0.0182
Brugia malayi putative neuropeptide receptor NPR1 0.0054 0.0236 0.0437
Loa Loa (eye worm) hypothetical protein 0.0017 0.0023 0.0016
Echinococcus multilocularis lipoxygenase domain containing protein 0.0042 0.0169 0.0155
Loa Loa (eye worm) hypothetical protein 0.0021 0.0046 0.0061
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0252 0.1383 0.7017
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0042 0.0033
Echinococcus multilocularis cpg binding protein 0.0065 0.0302 0.0288
Brugia malayi M-phase phosphoprotein, mpp8 0.0108 0.0552 0.1048
Trichomonas vaginalis glucosylceramidase, putative 0.0555 0.3134 0.7382
Brugia malayi G protein-coupled receptor F59B2.13 0.0054 0.0236 0.0437
Brugia malayi hypothetical protein 0.0054 0.0236 0.0437
Brugia malayi hypothetical protein 0.0054 0.0236 0.0437
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0044 0.0066
Echinococcus multilocularis lamin dm0 0.0058 0.026 0.0246
Trichomonas vaginalis helicase, putative 0.0014 0.0006 0.0013
Trypanosoma brucei NADH-ubiquinone oxidoreductase complex I subunit, putative 0.0024 0.0064 0.0125
Schistosoma mansoni lamin 0.0058 0.026 0.0289
Echinococcus multilocularis carboxylesterase 5A 0.0073 0.0347 0.0333
Plasmodium falciparum phosphatidylglycerophosphate synthase 0.0018 0.0027 0.0089
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0019 0.0035 0.0064
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.048 0.2701 0.3166
Loa Loa (eye worm) cytochrome P450 family protein 0.006 0.0273 0.05
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.002 0.0041 0.0075
Schistosoma mansoni nuclear receptor nhr-48 0.0429 0.2404 0.2816
Echinococcus multilocularis g protein coupled receptor 0.0054 0.0236 0.0222
Loa Loa (eye worm) TK protein kinase 0.0033 0.0113 0.0191
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0023 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0909 0.518 1
Schistosoma mansoni hypothetical protein 0.0039 0.0148 0.0157
Brugia malayi sulfakinin receptor protein 0.0054 0.0236 0.0437
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0143 0.075 0.2597
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0028 0.0086 0.0967
Echinococcus granulosus somatostatin receptor 0.0054 0.0236 0.0261
Echinococcus granulosus acetylcholinesterase 0.0073 0.0347 0.0392
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0909 0.518 0.5173
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0054 0.0236 0.0261
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Brugia malayi hypothetical protein 0.0429 0.2404 0.463
Schistosoma mansoni intermediate filament proteins 0.0058 0.026 0.0289
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0041 0.016 0.0145
Loa Loa (eye worm) hypothetical protein 0.048 0.2701 0.5201
Loa Loa (eye worm) hypothetical protein 0.0429 0.2404 0.4626
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Echinococcus granulosus intermediate filament protein 0.0058 0.026 0.0289
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.0087 0.0085
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0044 0.0181 0.0166
Brugia malayi nuclear hormone receptor 0.0909 0.518 1
Schistosoma mansoni sodium/chloride dependent transporter 0.0044 0.0181 0.0196
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0043 0.0174 0.0345
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0041 0.016 0.0171
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0133 0.0314
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0429 0.2404 0.2393
Brugia malayi Carboxylesterase family protein 0.0073 0.0347 0.0652
Echinococcus granulosus RUN 0.0042 0.0169 0.0182
Schistosoma mansoni alpha-1 adrenergic receptor 0.0054 0.0236 0.0261
Onchocerca volvulus 0.0909 0.518 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.0181 0.0322
Echinococcus granulosus sodium and chloride dependent glycine 0.0044 0.0181 0.0196
Brugia malayi beta-lactamase 0.0039 0.0148 0.0266
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0123 0.0638 0.0734
Schistosoma mansoni adrenodoxin 0.0024 0.0064 0.0058
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.0233 0.0432
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0019 0.0035 0.0064
Loa Loa (eye worm) melatonin receptor type 1A 0.0054 0.0236 0.0429
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0054 0.0236 0.0222
Schistosoma mansoni opsin-like receptor 0.0054 0.0236 0.0261
Trichomonas vaginalis Ferredoxin 4 0.0024 0.0064 0.015
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0148 0.0287
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.0236 0.0261
Loa Loa (eye worm) hypothetical protein 0.0044 0.0181 0.0322
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0041 0.0161 0.0284
Mycobacterium ulcerans hypothetical protein 0.0039 0.0148 0.041
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0019 0.0035 0.0064
Schistosoma mansoni biogenic amine receptor 0.0054 0.0236 0.0261
Loa Loa (eye worm) hypothetical protein 0.0027 0.008 0.0128
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0014 0.000000027476
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0019 0.0035 0.0036
Brugia malayi G-protein coupled receptor 0.0054 0.0236 0.0437
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0133 0.0314
Loa Loa (eye worm) hypothetical protein 0.048 0.2701 0.5201
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0082 0.0903
Brugia malayi Adrenodoxin-like protein, mitochondrial precursor, putative 0.0024 0.0064 0.0104
Brugia malayi Nuclear hormone receptor-like 1 0.048 0.2701 0.5205
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0429 0.2404 0.2816
Echinococcus multilocularis g-protein coupled receptor 0.0054 0.0236 0.0222
Brugia malayi Cytochrome P450 family protein 0.0038 0.0144 0.0259
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.0111 0.0564 0.1923
Onchocerca volvulus 0.0044 0.0181 0.0322
Brugia malayi Pre-SET motif family protein 0.0226 0.123 0.236
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0023 0.001
Trichomonas vaginalis glucosylceramidase, putative 0.0364 0.203 0.4782
Mycobacterium leprae PROBABLE POLYPRENYL-DIPHOSPHATE SYNTHASE GRCC1 (POLYPRENYL PYROPHOSPHATE SYNTHETASE) 0.0028 0.0086 0.1404
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0071 0.0336 0.0706
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0111 0.0564 0.8246
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0041 0.0161 0.0173
Brugia malayi 2Fe-2S iron-sulfur cluster binding domain containing protein 0.0024 0.0064 0.0104
Plasmodium vivax phosphatidylglycerophosphate synthase, putative 0.0018 0.0027 0.0089
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0148 0.0645
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0148 0.0348
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0043 0.0174 0.2482
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0747 0.4245 1
Brugia malayi putative neuropeptide receptor 0.0054 0.0236 0.0437
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0044 0.0181 0.2407
Trypanosoma cruzi adrenodoxin precursor, putative 0.0024 0.0064 0.01
Echinococcus granulosus G protein coupled receptor 139 0.0054 0.0236 0.0261
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0023 0.0016
Schistosoma mansoni neuropeptide f receptor 76f 0.0054 0.0236 0.0261
Plasmodium vivax geranylgeranyl pyrophosphate synthase 0.0111 0.0564 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0076 0.0179
Schistosoma mansoni cpg binding protein 0.0062 0.0282 0.0315
Schistosoma mansoni neuropeptide receptor 0.0054 0.0236 0.0261
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0044 0.003
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0429 0.2404 0.2393
Entamoeba histolytica hypothetical protein 0.0039 0.0148 0.198
Plasmodium falciparum transporter, putative 0.0044 0.0181 0.2919
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.0236 0.0222
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0123 0.0638 0.1214
Echinococcus multilocularis geminin 0.0181 0.0974 0.0961
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0044 0.0034
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0909 0.518 0.6088
Echinococcus multilocularis serotonin receptor 0.0054 0.0236 0.0222
Loa Loa (eye worm) hypothetical protein 0.0039 0.0148 0.0258
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0042 0.0028
Echinococcus multilocularis Ankyrin 0.0016 0.0015 0.0001
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0076 0.018
Onchocerca volvulus 0.0024 0.0064 0.0095
Schistosoma mansoni farnesyl pyrophosphate synthase 0.0111 0.0564 0.0648
Entamoeba histolytica hypothetical protein 0.0039 0.0148 0.198
Schistosoma mansoni tyrosine kinase 0.0041 0.016 0.0171
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0028 0.0086 1
Echinococcus granulosus tumor protein p63 0.0726 0.4123 0.4843
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0041 0.016 0.0145
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0909 0.518 0.5173
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0019 0.0035 0.0064
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0429 0.2404 0.4626
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0024 0.0064 0.01
Schistosoma mansoni microtubule-associated protein tau 0.1483 0.8499 1
Schistosoma mansoni retinoic acid receptor RXR 0.1014 0.579 0.6807
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0148 0.0287
Toxoplasma gondii ABC1 family protein 0.0039 0.0148 0.1905
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0429 0.2404 0.2393
Mycobacterium tuberculosis Probable geranylgeranyl pyrophosphate synthetase IdsA2 (ggppsase) (GGPP synthetase) (geranylgeranyl diphosphate synthase) 0.0111 0.0564 0.2792
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.0236 0.0261
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0076 0.018
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0044 0.0181 0.0196
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0044 0.0104
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0148 0.0645
Trichomonas vaginalis Ferredoxin 1 0.0024 0.0064 0.015
Brugia malayi Dopamine receptor protein 2 0.0054 0.0236 0.0437
Echinococcus granulosus retinoic acid receptor rxr beta a 0.1014 0.579 0.6807
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0044 0.0181 0.0196
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0946 0.5397 0.5391
Echinococcus granulosus dnaJ subfamily B 0.0879 0.5007 0.5884
Echinococcus multilocularis ubiquitin specific protease 41 0.0043 0.0174 0.016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0164 0.0386
Brugia malayi hypothetical protein 0.0054 0.0236 0.0437
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.0087 0.0072
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0023 0.0008
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0071 0.0336 0.0379
Loa Loa (eye worm) hypothetical protein 0.0429 0.2404 0.4626
Toxoplasma gondii cytochrome p450 superfamily protein 0.0019 0.0035 0.0188
Onchocerca volvulus 0.0058 0.026 0.0475
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0909 0.518 0.6088
Onchocerca volvulus 0.0054 0.0236 0.0429
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0019 0.0035 0.0036
Brugia malayi Serotonin receptor 0.0054 0.0236 0.0437
Trypanosoma cruzi polyprenyl synthase, putative 0.0028 0.0086 0.015
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0073 0.0347 0.0392
Loa Loa (eye worm) cytochrome P450 family protein 0.0038 0.0144 0.0251
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0016 0.0019 0.0004
Echinococcus granulosus neuropeptide receptor A26 0.0546 0.3084 0.3618
Mycobacterium ulcerans endonuclease IV 0.0082 0.0399 0.1324
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0064 0.01
Entamoeba histolytica protein kinase, putative 0.0033 0.0113 0.132
Loa Loa (eye worm) solute carrier family 6 member 4 0.0261 0.1432 0.2744
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0019 0.0035 0.0064
Giardia lamblia Farnesyl diphosphate synthase 0.0111 0.0564 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0909 0.518 1
Mycobacterium tuberculosis Probable oxidoreductase 0.0024 0.0064 0.0212
Loa Loa (eye worm) hypothetical protein 0.0429 0.2404 0.4626
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.0336 0.0706
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0023 0.0009
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0044 0.0082
Echinococcus granulosus ubiquitin specific protease 41 0.0043 0.0174 0.0188
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.0233 0.0424
Echinococcus multilocularis acetylcholinesterase 0.0073 0.0347 0.0333
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0006 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0006 0.0013
Echinococcus granulosus tyrosine protein kinase Fyn 0.0041 0.016 0.0171
Loa Loa (eye worm) runx1 0.0059 0.0269 0.0493
Mycobacterium tuberculosis Probable polyprenyl-diphosphate synthase GrcC2 (polyprenyl pyrophosphate synthetase) 0.0028 0.0086 0.0327
Wolbachia endosymbiont of Brugia malayi ferredoxin 0.0024 0.0064 0.6178
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.0236 0.0222
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0043 0.0174 0.0188
Loa Loa (eye worm) hypothetical protein 0.0053 0.0233 0.0424
Brugia malayi geranylgeranyl pyrophosphate synthetase 0.0028 0.0086 0.0147
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Schistosoma mansoni amine GPCR 0.0054 0.0236 0.0261
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0023 0.0008
Schistosoma mansoni sodium/chloride dependent transporter 0.0044 0.0181 0.0196
Plasmodium falciparum LCCL domain-containing protein 0.0042 0.0169 0.2703
Brugia malayi nuclear hormone receptor 0.0429 0.2404 0.463
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0044 0.0057
Onchocerca volvulus 0.0429 0.2404 0.4626
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0028 0.0086 0.015
Brugia malayi hypothetical protein 0.0054 0.0236 0.0437
Brugia malayi nuclear receptor NHR-88 0.0909 0.518 1
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0252 0.1383 0.4901
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0041 0.0161 0.0284
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0909 0.518 1
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0044 0.0181 0.4119
Leishmania major hypothetical protein, conserved 0.0024 0.0064 0.01
Brugia malayi hypothetical protein 0.0054 0.0236 0.0437
Brugia malayi hypothetical protein 0.048 0.2701 0.5205
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.0336 0.073
Onchocerca volvulus 0.0054 0.0236 0.0429
Mycobacterium ulcerans aldehyde dehydrogenase 0.013 0.0679 0.2342
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0044 0.0181 0.0196
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0148 0.0782 0.1698
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0133 0.0314
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0909 0.518 1
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0096 0.0481 0.055
Loa Loa (eye worm) hypothetical protein 0.0794 0.4515 0.8714
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0054 0.0236 0.0261
Echinococcus granulosus decaprenyl diphosphate synthase subunit 1 0.0028 0.0086 0.0084
Brugia malayi follicle stimulating hormone receptor 0.0054 0.0236 0.0437
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0054 0.0236 0.0437
Echinococcus multilocularis phospholipase D 0.0098 0.0491 0.0477
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0016 0.0016 0.0002
Loa Loa (eye worm) CYP4Cod1 0.0038 0.0144 0.0251
Loa Loa (eye worm) hypothetical protein 0.0093 0.0463 0.0869
Schistosoma mansoni hypothetical protein 0.0879 0.5007 0.5884
Echinococcus multilocularis geranylgeranyl pyrophosphate synthase 0.0028 0.0086 0.0072
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0909 0.518 0.6088
Loa Loa (eye worm) hypothetical protein 0.048 0.2701 0.5201
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0123 0.0638 0.3171
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0612 0.3462 0.3452
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0054 0.0236 0.0437
Loa Loa (eye worm) polyprenyl synthetase 0.0028 0.0086 0.0139
Echinococcus granulosus Nuclear hormone receptor HR96 0.0429 0.2404 0.2816
Mycobacterium tuberculosis Possible polyprenyl synthetase IdsB (polyprenyl transferase) (polyprenyl diphosphate synthase) 0.0028 0.0086 0.0327
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0043 0.0174 0.016
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0019 0.0035 0.0064
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.0104 0.0174
Loa Loa (eye worm) hypothetical protein 0.0909 0.518 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0054 0.0236 0.0261
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0054 0.0236 0.0222
Trichomonas vaginalis glucosylceramidase, putative 0.0555 0.3134 0.7382
Brugia malayi hypothetical protein 0.0054 0.0236 0.0437
Echinococcus granulosus g protein coupled receptor 0.0054 0.0236 0.0261
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0023 0.0008
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.0148 0.0157
Loa Loa (eye worm) hypothetical protein 0.0474 0.2667 0.5136
Schistosoma mansoni aldehyde dehydrogenase 0.013 0.0679 0.0784
Leishmania major hypothetical protein, conserved 0.0027 0.0082 0.0141
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0039 0.0091
Loa Loa (eye worm) hypothetical protein 0.0909 0.518 1
Brugia malayi hypothetical protein 0.0054 0.0236 0.0437
Echinococcus granulosus rhodopsin orphan GPCR 0.0054 0.0236 0.0261
Brugia malayi Nuclear hormone receptor E75 0.0429 0.2404 0.463
Loa Loa (eye worm) hypothetical protein 0.0429 0.2404 0.4626
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0909 0.518 1
Echinococcus granulosus phospholipase D 0.0098 0.0491 0.0562
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.0236 0.0261
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0148 0.2311
Schistosoma mansoni loxhd1 0.0042 0.0169 0.0182
Echinococcus multilocularis fmrfamide receptor 0.0054 0.0236 0.0222
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0044 0.0082
Mycobacterium ulcerans epimerase 0.0022 0.005 0.0053
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0019 0.0035 0.0064
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0044 0.0181 0.0196
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0148 0.0645
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0148 0.0348
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0019 0.0035 0.0064
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0041 0.016 0.0145
Trypanosoma brucei electron transfer protein, putative 0.0024 0.0064 0.0125
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0054 0.0236 0.0222
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0019 0.0044
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.013 0.0679 0.3386
Chlamydia trachomatis ferredoxin 0.0024 0.0064 0.0974
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.0236 0.0222
Echinococcus multilocularis thyroid hormone receptor alpha 0.0909 0.518 0.5173
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0054 0.0236 0.0222
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0054 0.0236 0.0429
Toxoplasma gondii phospholipase D active site domain-containing protein 0.0039 0.0148 0.1916
Echinococcus multilocularis tumor protein p63 0.0726 0.4123 0.4115
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.0174 0.0409
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0043 0.0174 0.0409
Toxoplasma gondii endonuclease IV APN 0.0082 0.0399 0.5738
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0054 0.0236 0.0261
Loa Loa (eye worm) G-protein coupled receptor 0.0054 0.0236 0.0429
Echinococcus granulosus geranylgeranyl pyrophosphate synthase 0.0028 0.0086 0.0084
Mycobacterium ulcerans flavodoxin oxidoreductase 0.0024 0.0064 0.0104
Echinococcus granulosus phospholipase d3 0.0021 0.0046 0.0037
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0023 0.0009
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0019 0.0035 0.0036
Trypanosoma brucei cardiolipin synthetase 0.0039 0.0148 0.0313
Brugia malayi isocitrate dehydrogenase 0.0017 0.0023 0.0024
Brugia malayi Steroid receptor seven-up type 2 0.0909 0.518 1
Toxoplasma gondii ferredoxin, putative 0.0024 0.0064 0.0625
Schistosoma mansoni hypothetical protein 0.0042 0.0169 0.0182
Trichomonas vaginalis glucosylceramidase, putative 0.0555 0.3134 0.7382
Echinococcus multilocularis serotonin receptor 0.0054 0.0236 0.0222
Loa Loa (eye worm) CXXC zinc finger family protein 0.0062 0.0282 0.0517
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.0236 0.0222
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0044 0.0035
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0043 0.0174 0.2492
Echinococcus granulosus farnesyl pyrophosphate synthase 0.0111 0.0564 0.0648
Echinococcus granulosus cpg binding protein 0.0065 0.0302 0.0339
Schistosoma mansoni nuclear receptor 0.0429 0.2404 0.2816
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0054 0.0236 0.0437
Schistosoma mansoni histamine h1 receptor 0.0054 0.0236 0.0261
Brugia malayi hypothetical protein 0.0018 0.0027 0.0034
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0044 0.0181 0.033
Loa Loa (eye worm) hypothetical protein 0.0429 0.2404 0.4626
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.002 0.0007
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0079 0.0384 0.037
Schistosoma mansoni hypothetical protein 0.0017 0.0023 0.0009
Echinococcus multilocularis neuropeptides capa receptor 0.0054 0.0236 0.0222
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0023 0.0009
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0044 0.0181 0.0196
Echinococcus granulosus peptide allatostatin:somatostatin 0.0054 0.0236 0.0261
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0044 0.0082
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0006 0.0013
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0019 0.0035 0.0036
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0023 0.0024
Echinococcus granulosus histone lysine methyltransferase setb 0.0034 0.0119 0.0123
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0076 0.0179
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0048 0.0205 0.0191
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0174 0.0188
Brugia malayi nuclear hormone receptor family member nhr-6 0.0429 0.2404 0.463
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0429 0.2404 0.4626
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0909 0.518 0.6088
Trichomonas vaginalis glucosylceramidase, putative 0.0364 0.203 0.4782
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0054 0.0236 0.0261
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0044 0.0112
Loa Loa (eye worm) hypothetical protein 0.0429 0.2404 0.4626
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0041 0.0161 0.0173
Onchocerca volvulus Protein ultraspiracle homolog 0.0909 0.518 1
Schistosoma mansoni neuropeptide receptor 0.0054 0.0236 0.0261
Echinococcus granulosus dna polymerase kappa 0.0021 0.0044 0.0035
Mycobacterium ulcerans electron transfer protein FdxB 0.0024 0.0064 0.0104
Toxoplasma gondii histone lysine methyltransferase SET1 0.0118 0.0608 0.891
Echinococcus multilocularis dna polymerase eta 0.0021 0.0044 0.003
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Mycobacterium ulcerans electron transfer protein 0.0024 0.0064 0.0104
Plasmodium vivax amine transporter, putative 0.0044 0.0181 0.2919
Echinococcus granulosus tyrosine protein kinase Fyn 0.0041 0.016 0.0171
Echinococcus granulosus GPCR family 2 0.0017 0.0023 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.0555 0.3134 0.7382
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0044 0.0181 0.0196
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0048 0.0205 0.0414
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0076 0.0179
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0076 0.0179
Trypanosoma cruzi cardiolipin synthetase, putative 0.0039 0.0148 0.0288
Schistosoma mansoni amine GPCR 0.0054 0.0236 0.0261
Brugia malayi hypothetical protein 0.0054 0.0236 0.0437
Loa Loa (eye worm) hypothetical protein 0.0429 0.2404 0.4626
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0221 0.1205 0.4254
Loa Loa (eye worm) hypothetical protein 0.0027 0.0082 0.0131
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.0111 0.0564 0.1329
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.013 0.0679 0.0784
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0019 0.0035 0.0064
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0123 0.0638 0.219
Loa Loa (eye worm) hypothetical protein 0.0909 0.518 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0205 0.0483
Schistosoma mansoni rab6-interacting 0.0042 0.0169 0.0182
Onchocerca volvulus Neuropeptide F receptor homolog 0.0054 0.0236 0.0429
Brugia malayi Polyprenyl synthetase family protein 0.0028 0.0086 0.0147
Schistosoma mansoni hypothetical protein 0.0054 0.0236 0.0261
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0023 0.0008
Echinococcus granulosus neuropeptide receptor 0.0054 0.0236 0.0261
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0261 0.1432 0.1671
Loa Loa (eye worm) hypothetical protein 0.0039 0.0148 0.0258
Echinococcus multilocularis ecdysone induced protein 78C 0.0909 0.518 0.5173
Trichomonas vaginalis glucosylceramidase, putative 0.0364 0.203 0.4782
Echinococcus granulosus serotonin transporter 0.0261 0.1432 0.1671
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0044 0.0181 0.0166
Echinococcus granulosus neuropeptide Y receptor 0.0054 0.0236 0.0261
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0119 0.0123
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0019 0.0035 0.0064
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0023 0.0034
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0019 0.0035 0.0064
Loa Loa (eye worm) hypothetical protein 0.0406 0.2271 0.4369
Entamoeba histolytica bifunctional short chain isoprenyl diphosphate synthase, putative 0.0028 0.0086 0.0802
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0019 0.0044
Echinococcus multilocularis microtubule associated protein 2 0.1483 0.8499 0.8497
Echinococcus granulosus transcription factor Dp 1 0.0041 0.0163 0.0175
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0082 0.0141
Brugia malayi CHD4 protein 0.0016 0.0016 0.0011
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0044 0.0181 0.0196
Entamoeba histolytica hypothetical protein 0.0039 0.0148 0.198
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0044 0.0082
Echinococcus granulosus fmrfamide receptor 0.0054 0.0236 0.0261
Echinococcus granulosus lamin 0.0058 0.026 0.0289
Echinococcus multilocularis dnaJ subfamily B 0.0879 0.5007 0.5
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0043 0.0174 0.0188
Mycobacterium ulcerans hypothetical protein 0.0121 0.0627 0.2152
Echinococcus multilocularis phospholipase d3 0.0021 0.0046 0.0031
Echinococcus granulosus tachykinin peptides receptor 99D 0.0054 0.0236 0.0261
Trypanosoma brucei phosphatidylglycerolphosphate synthase, mitochondrial 0.0018 0.0027 0.0045
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0794 0.4515 0.8715
Echinococcus granulosus tyrosine protein kinase Lyn 0.0041 0.016 0.0171
Trichomonas vaginalis set domain proteins, putative 0.0257 0.1409 0.3319
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0076 0.0179
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0054 0.0236 0.0222
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0044 0.003
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0028 0.0086 0.015
Brugia malayi nuclear receptor NHR-67 0.0429 0.2404 0.463
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0148 0.0645
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0909 0.518 1
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0041 0.0161 0.0379
Loa Loa (eye worm) hypothetical protein 0.0019 0.0034 0.0037
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0054 0.0236 0.0261
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0016 0.0019 0.0005
Plasmodium falciparum amino acid transporter, putative 0.0044 0.0181 0.2919
Trichomonas vaginalis glucosylceramidase, putative 0.0364 0.203 0.4782
Onchocerca volvulus 0.0108 0.0552 0.1041
Brugia malayi cytochrome P450 0.0019 0.0035 0.0048
Entamoeba histolytica phospholipase D, putative 0.0111 0.0566 1
Loa Loa (eye worm) histone methyltransferase 0.002 0.0042 0.0053
Brugia malayi Phospholipase D. Active site motif family protein 0.0021 0.0046 0.0069
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0909 0.518 1
Echinococcus multilocularis g protein coupled receptor 0.0054 0.0236 0.0222
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0054 0.0236 0.0261
Brugia malayi ecdysone receptor 0.0429 0.2404 0.463
Echinococcus granulosus carboxylesterase 5A 0.0073 0.0347 0.0392
Trichomonas vaginalis Ferredoxin 7 0.0024 0.0064 0.015
Loa Loa (eye worm) acetylcholinesterase 1 0.0073 0.0347 0.0645
Loa Loa (eye worm) hypothetical protein 0.0027 0.008 0.0128
Echinococcus granulosus tm gpcr rhodopsin 0.0946 0.5397 0.6345
Onchocerca volvulus 0.0106 0.0539 0.1016
Loa Loa (eye worm) hypothetical protein 0.0082 0.0399 0.0745
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0082 0.0166
Schistosoma mansoni cpg binding protein 0.0065 0.0302 0.0339
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0082 0.0399 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0169 0.0299
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0023 0.0024
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0148 0.0348
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0909 0.518 1
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0096 0.0481 0.0468
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0034 0.0119 0.0104
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0044 0.0181 0.0196
Entamoeba histolytica phospholipase D, putative 0.0111 0.0566 1
Leishmania major C-8 sterol isomerase-like protein 0.0794 0.4515 1
Echinococcus multilocularis G protein coupled receptor 139 0.0054 0.0236 0.0222
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0028 0.0086 1
Brugia malayi hypothetical protein 0.0027 0.0082 0.0139
Onchocerca volvulus 0.0062 0.0282 0.0517
Trypanosoma cruzi DNA polymerase eta, putative 0.0021 0.0044 0.0057
Brugia malayi Tachykinin-like peptides receptor 99D 0.0054 0.0236 0.0437
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.0233 0.0432
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0123 0.0638 0.0624
Loa Loa (eye worm) hypothetical protein 0.0429 0.2404 0.4626
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0148 0.0312
Schistosoma mansoni sodium/chloride dependent transporter 0.0261 0.1432 0.1671
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0091 0.0213
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0038 0.0144 0.0396
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0071 0.0336 0.0623
Chlamydia trachomatis geranylgeranyl pyrophosphate synthase 0.0028 0.0086 0.1577
Echinococcus multilocularis fmrfamide receptor 0.0054 0.0236 0.0222
Brugia malayi Cytochrome P450 family protein 0.006 0.0273 0.0508
Trypanosoma cruzi cytochrome P450, putative 0.0038 0.0144 0.0278
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0132 0.0689 0.0795
Echinococcus multilocularis neuropeptide s receptor 0.0546 0.3084 0.3074
Echinococcus granulosus sex peptide receptor 0.0054 0.0236 0.0261
Brugia malayi CXXC zinc finger family protein 0.0062 0.0282 0.0525
Mycobacterium tuberculosis Hypothetical oxidoreductase 0.0024 0.0064 0.0212
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0107 0.0251
Schistosoma mansoni phospholipase D 0.0111 0.0566 0.065
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0054 0.0236 0.0429
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0123 0.0638 0.1376
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0148 0.0134
Echinococcus granulosus acetylcholinesterase 0.0073 0.0347 0.0392
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0148 0.0348
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0054 0.0236 0.0222
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0054 0.0236 0.0261
Loa Loa (eye worm) SRC-1 0.0041 0.016 0.0281
Loa Loa (eye worm) serotonin transporter b 0.0261 0.1432 0.2744
Loa Loa (eye worm) TK protein kinase 0.0037 0.0137 0.0237
Treponema pallidum hypothetical protein 0.0121 0.0627 0.4019
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.048 0.2701 0.269
Brugia malayi Dopamine receptor protein 1 0.0054 0.0236 0.0437
Mycobacterium leprae Probable lipase LipE 0.0039 0.0148 0.3095
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0023 0.0034
Schistosoma mansoni glutathione synthetase 0.0028 0.0086 0.0084
Trypanosoma brucei farnesyl pyrophosphate synthase 0.0111 0.0564 0.1235
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0909 0.518 0.5173
Schistosoma mansoni lipoxygenase 0.0185 0.0997 0.1158
Schistosoma mansoni hypothetical protein 0.0181 0.0974 0.1131
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0148 0.041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0092 0.0217
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0048 0.0205 0.0225
Schistosoma mansoni hypothetical protein 0.0054 0.0236 0.0261
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0119 0.0104
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0104 0.0106
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0246 0.1349 0.684
Loa Loa (eye worm) hypothetical protein 0.0044 0.0181 0.0322
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0076 0.018
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0909 0.518 0.6088
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0043 0.0174 0.0345
Loa Loa (eye worm) hypothetical protein 0.0034 0.0123 0.021
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0054 0.0236 0.0222
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0039 0.0153 0.0277
Onchocerca volvulus 0.0058 0.026 0.0475
Leishmania major cytochrome p450-like protein 0.0019 0.0035 0.0036
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0252 0.1383 0.4901
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0054 0.0236 0.0261
Brugia malayi Carboxylesterase family protein 0.0073 0.0347 0.0652
Onchocerca volvulus 0.0044 0.0181 0.0322
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0048 0.0205 0.0414
Schistosoma mansoni growth hormone secretagogue receptor 0.0054 0.0236 0.0261
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0909 0.518 1
Echinococcus multilocularis neuropeptides capa receptor 0.0054 0.0236 0.0222
Loa Loa (eye worm) hypothetical protein 0.048 0.2701 0.5201
Trichomonas vaginalis glucosylceramidase, putative 0.0364 0.203 0.4782
Echinococcus multilocularis Protein lozenge 0.0059 0.0269 0.0255
Onchocerca volvulus 0.0042 0.0169 0.0299
Trypanosoma cruzi adrenodoxin precursor, putative 0.0024 0.0064 0.01
Echinococcus granulosus ferredoxin 0.0024 0.0064 0.0058
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0044 0.0181 0.033
Echinococcus multilocularis conserved hypothetical protein 0.0744 0.4226 0.4218
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0071 0.0336 0.5597
Echinococcus granulosus nuclear receptor nhr 48 0.0429 0.2404 0.2816
Echinococcus granulosus serotonin receptor 0.0054 0.0236 0.0261
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0054 0.0236 0.0261
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0044 0.0034
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0019 0.0035 0.0064
Schistosoma mansoni hypothetical protein 0.0036 0.0136 0.0143
Brugia malayi orphan nuclear receptor NR2E1 0.0429 0.2404 0.463
Echinococcus granulosus nuclear factor of activated T cells 5 0.0079 0.0384 0.0435
Loa Loa (eye worm) phospholipase D 0.0021 0.0046 0.0061
Echinococcus multilocularis neuropeptide FF receptor 2 0.0054 0.0236 0.0222
Trypanosoma cruzi adrenodoxin precursor, putative 0.0024 0.0064 0.01
Echinococcus multilocularis lipoxygenase domain containing protein 0.0042 0.0169 0.0155
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0044 0.0181 0.0196
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0044 0.0035
Trypanosoma cruzi cardiolipin synthetase, putative 0.0039 0.0148 0.0288
Trypanosoma cruzi solanesyl-diphosphate synthase 0.0028 0.0086 0.015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0113 0.0266
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0909 0.518 0.6088
Echinococcus granulosus tyrosine protein kinase HCK 0.0033 0.0113 0.0116
Trypanosoma brucei Emopamil binding protein, putative 0.0148 0.0782 0.1719
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0044 0.0181 0.0196
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0041 0.0161 0.0292
Schistosoma mansoni coup transcription factor 0.0909 0.518 0.6088
Echinococcus multilocularis Adrenodoxin, mitochondrial 0.0024 0.0064 0.0049
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0148 0.0348
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0133 0.0314
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.0236 0.0222
Brugia malayi Uncoordinated protein 44 0.0015 0.0014 0.0008
Schistosoma mansoni neuropeptide F-like receptor 0.0054 0.0236 0.0261
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0022 0.005 0.0053
Echinococcus multilocularis FTZ F1 alpha 0.0909 0.518 0.5173
Echinococcus multilocularis Polycystic kidney disease protein 0.0042 0.0169 0.0155
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Loa Loa (eye worm) nuclear receptor NHR-67 0.0429 0.2404 0.4626
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0747 0.4245 1
Plasmodium falciparum octaprenyl pyrophosphate synthase 0.0028 0.0086 0.1172
Brugia malayi conserved hypotetical protein 0.0429 0.2404 0.463
Trichomonas vaginalis aldehyde oxidase, putative 0.0747 0.4245 1
Loa Loa (eye worm) hypothetical protein 0.0429 0.2404 0.4626
Schistosoma mansoni hypothetical protein 0.0017 0.0023 0.0009
Echinococcus granulosus tyrosine protein kinase Src42A 0.0035 0.013 0.0136
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0048 0.0205 0.0414
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0909 0.518 0.6088
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.048 0.2701 0.3166
Schistosoma mansoni lozenge 0.0059 0.0269 0.03
Leishmania major cardiolipin synthetase, putative 0.0018 0.0027 0.0019
Onchocerca volvulus 0.0054 0.0236 0.0429
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0054 0.0236 0.0222
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Mycobacterium tuberculosis Possible electron transfer protein FdxB 0.0024 0.0064 0.0212
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0044 0.0181 0.0322
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0148 0.0645
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0019 0.0035 0.0064
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Schistosoma mansoni amine GPCR 0.0411 0.23 0.2694
Brugia malayi ORL1-like opioid receptor 0.0054 0.0236 0.0437
Echinococcus granulosus neuropeptides capa receptor 0.0054 0.0236 0.0261
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0019 0.0044
Schistosoma mansoni geranylgeranyl pyrophosphate synthase 0.0028 0.0086 0.0084
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0082 0.0399 0.0753
Echinococcus granulosus 7tm_1 domain containing protein 0.0054 0.0236 0.0261
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0044 0.0057
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0429 0.2404 0.463
Leishmania major cytochrome p450-like protein 0.0019 0.0035 0.0036
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0044 0.0181 0.0322
Toxoplasma gondii hypothetical protein 0.0044 0.0181 0.2407
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0054 0.0236 0.0222
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0044 0.0082
Trichomonas vaginalis Ferredoxin 6 0.0024 0.0064 0.015
Onchocerca volvulus 0.0257 0.141 0.2702
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0429 0.2404 0.2393
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0082 0.1095
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0037 0.0137 0.0144
Schistosoma mansoni hypothetical protein 0.0019 0.0035 0.0024
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0014 0.0008
Echinococcus granulosus Ankyrin 0.0016 0.0015 0.0001
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0082 0.1095
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0019 0.0035 0.0064
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0909 0.518 0.6088
Echinococcus multilocularis neuropeptide Y receptor 0.0054 0.0236 0.0222
Trypanosoma brucei unspecified product 0.0021 0.0044 0.0082
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.0236 0.0261
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0044 0.0181 0.0196
Echinococcus granulosus neuropeptide s receptor 0.0546 0.3084 0.3618
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0794 0.4515 1
Brugia malayi hypothetical protein 0.0054 0.0236 0.0437
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0054 0.0236 0.0261
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0148 0.0157
Onchocerca volvulus 0.0042 0.0169 0.0299
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.0104 0.0182
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Trypanosoma brucei cytochrome P450, putative 0.0038 0.0144 0.0303
Echinococcus granulosus tm gpcr rhodopsin 0.0612 0.3462 0.4063
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0429 0.2404 0.4626
Schistosoma mansoni zinc finger protein 0.0429 0.2404 0.2816
Trypanosoma cruzi farnesyl pyrophosphate synthase 0.0111 0.0564 0.1213
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.0148 0.0133
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0039 0.0091
Echinococcus multilocularis tyrosine protein kinase Blk 0.0037 0.0137 0.0122
Echinococcus multilocularis dro:myosuppressin receptor 0.0054 0.0236 0.0222
Onchocerca volvulus 0.0261 0.1432 0.2744
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0143 0.075 0.3749
Schistosoma mansoni hypothetical protein 0.0017 0.0023 0.0009
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.0148 0.0157
Echinococcus granulosus tyrosine protein kinase Fyn 0.0041 0.016 0.0171
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0909 0.518 0.5173
Toxoplasma gondii ferodoxin FD 0.0024 0.0064 0.0625
Echinococcus granulosus rhodopsin orphan GPCR 0.0054 0.0236 0.0261
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0039 0.0153 0.0269
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0023 0.0009
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0058 0.026 0.0475
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.0236 0.0261
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0039 0.0148 0.0287
Loa Loa (eye worm) hypothetical protein 0.0909 0.518 1
Schistosoma mansoni adrenodoxin 0.0024 0.0064 0.0058
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.013 0.0679 0.1469
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0054 0.0236 0.0261
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0909 0.518 1
Schistosoma mansoni neuropeptide receptor 0.0054 0.0236 0.0261
Brugia malayi Phospholipase D. Active site motif family protein 0.0039 0.0148 0.0268
Loa Loa (eye worm) hypothetical protein 0.0429 0.2404 0.4626
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0016 0.0019 0.0026
Loa Loa (eye worm) CHromoDomain protein family member 0.0016 0.0016 0.0003
Brugia malayi Pre-SET motif family protein 0.0034 0.0119 0.021
Mycobacterium tuberculosis Conserved protein 0.0039 0.0148 0.0645
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0037 0.0137 0.0122
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0909 0.518 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Schistosoma mansoni tyrosine kinase 0.0041 0.016 0.0171
Brugia malayi Nuclear hormone receptor-like 1 0.048 0.2701 0.5205
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0096 0.0481 0.055
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0041 0.0161 0.2107
Brugia malayi Nuclear hormone receptor E75 0.0429 0.2404 0.463
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0148 0.0645
Loa Loa (eye worm) hypothetical protein 0.0044 0.0181 0.0322
Echinococcus granulosus ecdysone induced protein 78C 0.0909 0.518 0.6088
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Echinococcus multilocularis serotonin transporter 0.0261 0.1432 0.142
Schistosoma mansoni cellular tumor antigen P53 0.0106 0.0539 0.0619
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0044 0.0082
Loa Loa (eye worm) polyprenyl synthetase 0.0111 0.0564 0.1064
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0054 0.0236 0.0261
Mycobacterium ulcerans oxidoreductase 0.0024 0.0064 0.0104
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0048 0.0205 0.0377
Echinococcus granulosus 7TM GPCR rhodopsin 0.0054 0.0236 0.0261
Loa Loa (eye worm) hypothetical protein 0.0016 0.0015 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0006 0.0013
Echinococcus granulosus g-protein coupled receptor 0.0054 0.0236 0.0261
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Echinococcus multilocularis somatostatin receptor 0.0054 0.0236 0.0222
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0148 0.0782 0.1698
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0054 0.0236 0.0429
Echinococcus granulosus rhodopsin orphan GPCR 0.0054 0.0236 0.0261
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0148 0.0348
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0076 0.018
Brugia malayi Cytochrome P450 family protein 0.0019 0.0035 0.0048
Schistosoma mansoni biogenic amine (5HT) receptor 0.0054 0.0236 0.0261
Schistosoma mansoni trans-prenyltransferase 0.0028 0.0086 0.0084
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0044 0.0057
Schistosoma mansoni hypothetical protein 0.0054 0.0236 0.0261
Trichomonas vaginalis glucosylceramidase, putative 0.0364 0.203 0.4782
Mycobacterium tuberculosis Possible oxygenase 0.0024 0.0064 0.0212
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0044 0.0035
Loa Loa (eye worm) intermediate filament protein 0.0058 0.026 0.0475
Mycobacterium ulcerans polyprenyl synthetase IdsB 0.0028 0.0086 0.0186
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0039 0.0148 0.0312
Echinococcus multilocularis 0.0019 0.0035 0.0021
Echinococcus granulosus tyrosine protein kinase Src64B 0.0041 0.016 0.0171
Echinococcus granulosus neuropeptide FF receptor 2 0.0054 0.0236 0.0261
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0035 0.013 0.0116
Brugia malayi RE15519p 0.0054 0.0236 0.0437
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0016 0.0019 0.0026
Echinococcus multilocularis sodium and chloride dependent glycine 0.0044 0.0181 0.0166
Brugia malayi hypothetical protein 0.0429 0.2404 0.463
Schistosoma mansoni neuropeptide F-like receptor 0.0054 0.0236 0.0261
Loa Loa (eye worm) carboxylesterase 0.0073 0.0347 0.0645
Loa Loa (eye worm) hypothetical protein 0.0072 0.0342 0.0635
Echinococcus granulosus biogenic amine 5HT receptor 0.0054 0.0236 0.0261
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0054 0.0236 0.0261
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0023 0.0009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0909 0.518 1
Trypanosoma brucei solanesyl-diphosphate synthase, putative 0.0028 0.0086 0.0175
Loa Loa (eye worm) hypothetical protein 0.0261 0.1432 0.2744
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0054 0.0236 0.0437
Schistosoma mansoni nuclear hormone receptor 0.0429 0.2404 0.2816
Loa Loa (eye worm) doublecortin family protein 0.0042 0.0169 0.0299
Trypanosoma brucei DNA polymerase eta, putative 0.0021 0.0044 0.0082
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0092 0.0217
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Onchocerca volvulus 0.0054 0.0236 0.0429
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0044 0.0057
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.002 0.0007
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0041 0.0059
Echinococcus granulosus rhodopsin orphan GPCR 0.0054 0.0236 0.0261
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0909 0.518 0.6088
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0054 0.0236 0.0261
Plasmodium falciparum ferredoxin, putative 0.0024 0.0064 0.0758
Loa Loa (eye worm) hypothetical protein 0.0039 0.0148 0.0258
Loa Loa (eye worm) hypothetical protein 0.0106 0.0539 0.1016
Toxoplasma gondii hypothetical protein 0.0044 0.0181 0.2407
Loa Loa (eye worm) hypothetical protein 0.048 0.2701 0.5201
Leishmania major hypothetical protein, conserved 0.0039 0.0148 0.0287
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0016 0.0015 0.0001
Echinococcus multilocularis lamin 0.0058 0.026 0.0246
Brugia malayi hypothetical protein 0.0042 0.0169 0.0307
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0043 0.0174 0.016
Schistosoma mansoni amine GPCR 0.0054 0.0236 0.0261
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0044 0.0181 0.2407
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0534 0.3014 0.3004
Brugia malayi ecdysteroid receptor 0.0909 0.518 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0909 0.518 0.6088
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Mycobacterium ulcerans oxidoreductase 0.0024 0.0064 0.0104
Echinococcus multilocularis G-protein coupled receptor, putative 0.0054 0.0236 0.0222
Loa Loa (eye worm) hypothetical protein 0.0058 0.026 0.0475
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Mycobacterium ulcerans aldehyde dehydrogenase 0.013 0.0679 0.2342
Echinococcus multilocularis neuropeptide receptor A26 0.0546 0.3084 0.3074
Loa Loa (eye worm) hypothetical protein 0.0054 0.0236 0.0429
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0041 0.0161 0.0147
Onchocerca volvulus 0.0429 0.2404 0.4626
Echinococcus granulosus g protein coupled receptor 0.0054 0.0236 0.0261
Brugia malayi larval opioid receptor 0.0054 0.0236 0.0437
Schistosoma mansoni sodium-dependent amino acid transporter 0.0044 0.0181 0.0196
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0041 0.0161 0.2237
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0148 0.0348
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0054 0.0236 0.0261
Echinococcus granulosus rhodopsin orphan GPCR 0.0054 0.0236 0.0261
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0071 0.0336 0.0322
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0048 0.0205 0.0414
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0041 0.0161 0.0341
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0039 0.0153 0.0139
Loa Loa (eye worm) TYRA-2 protein 0.0054 0.0236 0.0429
Echinococcus granulosus alpha 1A adrenergic receptor 0.0054 0.0236 0.0261
Echinococcus multilocularis rhodopsin orphan GPCR 0.0054 0.0236 0.0222
Leishmania major ferredoxin 2fe-2s-like protein 0.0024 0.0064 0.01
Brugia malayi Doublecortin family protein 0.0042 0.0169 0.0307
Plasmodium falciparum adrenodoxin-type ferredoxin, putative 0.0024 0.0064 0.0758
Echinococcus multilocularis phospholipase D1 0.0111 0.0566 0.0552

Activities

Activity type Activity value Assay description Source Reference
ED50 (functional) = 8.7 uM Myorelaxant activity of thecompound against insulinsecretion in the pancreatic islets ofrat; (activity expressed as ED50) ChEMBL. 15658874
pED50 (binding) = 5.06 Inhibition of SUR2A/kir6.2 channel in Wistar rat thoracic aorta assessed as relaxation of Kcl-induced contraction ChEMBL. 18353509
Residual secretion (functional) = 58.9 % Percentage of residual insulinsecretion value in the pancreaticislets of rat after treatment with thecompound at 10 uM concentration ChEMBL. 15658874

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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