Detailed information for compound 375854

Basic information

Technical information
  • TDR Targets ID: 375854
  • Name: methyl (7S)-7-[[2-(5-methoxy-2-methyl-1H-indo l-3-yl)acetyl]amino]-8-oxo-8-[2-(2-phenyl-1H- indol-3-yl)ethylamino]octanoate
  • MW: 622.753 | Formula: C37H42N4O5
  • H donors: 4 H acceptors: 3 LogP: 6.2 Rotable bonds: 18
    Rule of 5 violations (Lipinski): 2
  • SMILES: COC(=O)CCCCC[C@@H](C(=O)NCCc1c([nH]c2c1cccc2)c1ccccc1)NC(=O)Cc1c(C)[nH]c2c1cc(OC)cc2
  • InChi: 1S/C37H42N4O5/c1-24-29(30-22-26(45-2)18-19-32(30)39-24)23-34(42)40-33(16-8-5-9-17-35(43)46-3)37(44)38-21-20-28-27-14-10-11-15-31(27)41-36(28)25-12-6-4-7-13-25/h4,6-7,10-15,18-19,22,33,39,41H,5,8-9,16-17,20-21,23H2,1-3H3,(H,38,44)(H,40,42)/t33-/m0/s1
  • InChiKey: WBURJDQDBKPXRR-XIFFEERXSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (7S)-7-[[2-(5-methoxy-2-methyl-1H-indol-3-yl)-1-oxoethyl]amino]-8-oxo-8-[2-(2-phenyl-1H-indol-3-yl)ethylamino]octanoic acid methyl ester
  • methyl (7S)-7-[2-(5-methoxy-2-methyl-1H-indol-3-yl)ethanoylamino]-8-oxo-8-[2-(2-phenyl-1H-indol-3-yl)ethylamino]octanoate
  • (7S)-8-keto-7-[[2-(5-methoxy-2-methyl-1H-indol-3-yl)acetyl]amino]-8-[2-(2-phenyl-1H-indol-3-yl)ethylamino]caprylic acid methyl ester

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens histone deacetylase 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Leishmania braziliensis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania infantum histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Echinococcus multilocularis histone deacetylase 1 Get druggable targets OG5_126742 All targets in OG5_126742
Trichomonas vaginalis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Entamoeba histolytica histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Schistosoma mansoni histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative Get druggable targets OG5_126742 All targets in OG5_126742
Theileria parva histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Giardia lamblia Histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Trichomonas vaginalis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Cryptosporidium parvum histone deacetylase HDA2/Rpd3p Get druggable targets OG5_126742 All targets in OG5_126742
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania major histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Plasmodium vivax histone deacetylase 1, putative Get druggable targets OG5_126742 All targets in OG5_126742
Candida albicans one of two distinct genes with strong similarity to S. cerevisiae RPD3 (YNL330C) SIN3 histone deacetylase complex component Get druggable targets OG5_126742 All targets in OG5_126742
Trypanosoma brucei histone deacetylase 1 Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania mexicana histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Trichomonas vaginalis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Trypanosoma congolense histone deacetylase-like 1 protein, putative Get druggable targets OG5_126742 All targets in OG5_126742
Schistosoma mansoni histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Loa Loa (eye worm) histone deacetylase 1 Get druggable targets OG5_126742 All targets in OG5_126742
Cryptosporidium hominis histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Loa Loa (eye worm) histone deacetylase 3 Get druggable targets OG5_126742 All targets in OG5_126742
Trichomonas vaginalis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Plasmodium falciparum histone deacetylase 1 Get druggable targets OG5_126742 All targets in OG5_126742
Neospora caninum histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Plasmodium knowlesi histone deacetylase 1, putative Get druggable targets OG5_126742 All targets in OG5_126742
Echinococcus granulosus histone deacetylase 3 Get druggable targets OG5_126742 All targets in OG5_126742
Trypanosoma brucei gambiense histone deacetylase 1,histone deacetylase-like 1 protein, putative Get druggable targets OG5_126742 All targets in OG5_126742
Candida albicans one of two distinct genes with strong similarity to S. cerevisiae RPD3 (YNL330C) SIN3 histone deacetylase complex component Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania infantum histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania donovani histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Brugia malayi histone deacetylase 3 (HD3) Get druggable targets OG5_126742 All targets in OG5_126742
Neospora caninum hypothetical protein Get druggable targets OG5_126742 All targets in OG5_126742
Trypanosoma cruzi histone deacetylase 1, putative Get druggable targets OG5_126742 All targets in OG5_126742
Cryptosporidium parvum RPD3/HD1 histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Babesia bovis histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania donovani histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania mexicana histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Plasmodium berghei histone deacetylase 1, putative Get druggable targets OG5_126742 All targets in OG5_126742
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126742 All targets in OG5_126742
Trichomonas vaginalis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Echinococcus multilocularis histone deacetylase 3 Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania braziliensis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Cryptosporidium hominis histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania major histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Schistosoma japonicum ko:K06067 histone deacetylase 1/2, putative Get druggable targets OG5_126742 All targets in OG5_126742
Toxoplasma gondii histone deacetylase HDAC2 Get druggable targets OG5_126742 All targets in OG5_126742
Plasmodium yoelii histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Trichomonas vaginalis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Trypanosoma cruzi histone deacetylase 1, putative Get druggable targets OG5_126742 All targets in OG5_126742
Echinococcus granulosus histone deacetylase 1 Get druggable targets OG5_126742 All targets in OG5_126742
Schistosoma japonicum ko:K01463 Hdac3 [EC:3.5.1.-], putative Get druggable targets OG5_126742 All targets in OG5_126742
Toxoplasma gondii histone deacetylase HDAC3 Get druggable targets OG5_126742 All targets in OG5_126742
Candida albicans one of two distinct genes with strong similarity to S. cerevisiae RPD3 (YNL330C) SIN3 histone deacetylase complex component Get druggable targets OG5_126742 All targets in OG5_126742
Brugia malayi histone deacetylase 1 (HD1) Get druggable targets OG5_126742 All targets in OG5_126742
Brugia malayi Histone deacetylase 1 Get druggable targets OG5_126742 All targets in OG5_126742
Candida albicans one of two distinct genes with strong similarity to S. cerevisiae RPD3 (YNL330C) SIN3 histone deacetylase complex component Get druggable targets OG5_126742 All targets in OG5_126742
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi glucose transporter, putative 0.0018 0.002 0.0051
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.002 0.0026 0.0345
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.0071
Mycobacterium tuberculosis Possible two component sensor kinase 0.0018 0.0021 0.0243
Schistosoma mansoni heat shock protein 0.0046 0.0099 0.0635
Plasmodium vivax histone deacetylase, putative 0.0022 0.0031 0.0086
Onchocerca volvulus 0.0067 0.016 0.016
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.003 0.0211
Brugia malayi putative neuropeptide receptor 0.0022 0.003 0.0042
Brugia malayi hypothetical protein 0.0022 0.003 0.0042
Schistosoma mansoni histone deacetylase hda2 0.0022 0.0031 0.0199
Schistosoma mansoni hypothetical protein 0.0022 0.003 0.0194
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.0036 0.0057
Schistosoma mansoni intermediate filament proteins 0.005 0.0111 0.0717
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0102 0.0261 0.0413
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.003 0.0054 0.0085
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0161
Toxoplasma gondii LsmAD domain-containing protein 0.0103 0.0264 0.0949
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0073 0.0177 0.028
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0022 0.003 0.0122
Schistosoma mansoni neuropeptide receptor 0.0022 0.003 0.0194
Leishmania major heat shock protein 83-1 0.0046 0.0099 0.0343
Plasmodium vivax metacaspase 1, putative 0.0072 0.0174 0.0617
Schistosoma mansoni thyroid hormone receptor 0.0024 0.0036 0.023
Echinococcus multilocularis geminin 0.0427 0.1192 0.1888
Brugia malayi G protein-coupled receptor F59B2.13 0.0022 0.003 0.0042
Brugia malayi hypothetical protein 0.0103 0.0264 0.0363
Trypanosoma cruzi target of rapamycin kinase 3 0.0031 0.0058 0.0192
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0018 0.0021 0.0243
Schistosoma mansoni opsin-like receptor 0.0022 0.003 0.0194
Brugia malayi Histone deacetylase family protein 0.0022 0.0031 0.0043
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.003 0.0194
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0041 0.0087 0.1391
Toxoplasma gondii histone deacetylase HDAC2 0.0077 0.0188 0.067
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.003 0.0048
Schistosoma mansoni caspase-7 (C14 family) 0.019 0.0513 0.3303
Schistosoma mansoni hypothetical protein 0.0083 0.0206 0.1324
Brugia malayi aryl hydrocarbon receptor AHR-1 0.0025 0.0038 0.0053
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.002 0.0026 0.0076
Schistosoma mansoni hypothetical protein 0.0089 0.0224 0.1444
Loa Loa (eye worm) hypothetical protein 0.0054 0.0122 0.0996
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0022 0.0031 0.0216
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0029 0.0052 0.0082
Brugia malayi Dopamine receptor protein 2 0.0022 0.003 0.0042
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0073 0.0177 0.0243
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0094 0.0239 0.4027
Echinococcus granulosus neuropeptide Y receptor 0.0022 0.003 0.0122
Schistosoma mansoni histamine h1 receptor 0.0022 0.003 0.0194
Schistosoma mansoni smad1 5 8 and 0.0014 0.0008 0.0052
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.003 0.0194
Schistosoma mansoni amine GPCR 0.0022 0.003 0.0194
Brugia malayi Major Facilitator Superfamily protein 0.0018 0.002 0.0027
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0029 0.0052 0.0171
Brugia malayi neuropeptide F receptor 0.0022 0.003 0.0042
Trypanosoma cruzi hexose transporter, putative 0.0018 0.002 0.0051
Loa Loa (eye worm) hypothetical protein 0.0277 0.0762 0.6221
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0037 0.0074 0.0254
Trypanosoma cruzi DNA topoisomerase II, putative 0.0224 0.061 0.2236
Brugia malayi Dopamine receptor 0.0022 0.003 0.0042
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0102 0.0261 0.0413
Echinococcus granulosus g-protein coupled receptor 0.0022 0.003 0.0122
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0014 0.0007 0.0044
Loa Loa (eye worm) hypothetical protein 0.0024 0.0036 0.0292
Schistosoma mansoni cpg binding protein 0.0048 0.0105 0.0675
Onchocerca volvulus 0.0022 0.003 0.003
Plasmodium falciparum lysine--tRNA ligase 0.0022 0.0031 0.0085
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0022 0.003 0.0194
Mycobacterium ulcerans two component sensor kinase MprB 0.0018 0.0021 0.0106
Trypanosoma brucei THT1 - hexose transporter, putative 0.0035 0.0067 0.0227
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0012 0.0004 0.0015
Trichomonas vaginalis DNA topoisomerase II, putative 0.0242 0.0661 0.5183
Plasmodium falciparum protein kinase 7 0.0276 0.076 0.2785
Giardia lamblia DINP protein human, muc B family 0.002 0.0025 0.0057
Mycobacterium leprae putative cytochrome p450 0.002 0.0026 0.021
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0174 0.1347
Plasmodium vivax sugar transporter, putative 0.0018 0.002 0.0045
Echinococcus granulosus bloom syndrome protein 0.0098 0.0248 0.1002
Echinococcus multilocularis voltage gated potassium channel 0.0018 0.0019 0.0031
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0022 0.003 0.0246
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0161
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0024 0.0036 0.0049
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0024 0.0036 0.0145
Schistosoma mansoni aryl hydrocarbon receptor nuclear translocator homolog (darnt) 0.0025 0.004 0.026
Trichomonas vaginalis heat shock protein, putative 0.0027 0.0046 0.0339
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0018 0.0021 0.0243
Trypanosoma cruzi PAB1-binding protein , putative 0.0103 0.0264 0.0955
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0022 0.003 0.0194
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0018 0.0021 0.0054
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0058 0.043
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0019 0.0125
Loa Loa (eye worm) hypothetical protein 0.0022 0.0031 0.025
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0024 0.0036 0.0145
Giardia lamblia Heat shock protein HSP 90-alpha 0.0027 0.0046 0.0137
Toxoplasma gondii DNA topoisomerase 2, putative 0.0242 0.0661 0.2421
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0078 0.0267
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0161
Toxoplasma gondii cytochrome p450 superfamily protein 0.002 0.0026 0.007
Trypanosoma brucei DNA topoisomerase ii 0.0233 0.0635 0.233
Echinococcus granulosus mothers against decapentaplegic 5 0.0014 0.0008 0.0033
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0019 0.0023 0.0124
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0024 0.0036 0.023
Trichomonas vaginalis sugar transporter, putative 0.0018 0.002 0.0131
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0051 0.0113 0.0179
Schistosoma mansoni hypothetical protein 0.0022 0.003 0.0194
Giardia lamblia DNA topoisomerase III 0.0018 0.0019 0.0038
Trichomonas vaginalis sugar transporter, putative 0.0018 0.002 0.0131
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0029 0.0203
Schistosoma mansoni smad1 5 8 and 0.0014 0.0008 0.0052
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0046 0.0101 0.0407
Brugia malayi hypothetical protein 0.0122 0.0318 0.0438
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.0071
Onchocerca volvulus 0.0018 0.002 0.002
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0106 0.0683
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0014 0.0008 0.0006
Leishmania major 4-coumarate:coa ligase-like protein 0.0019 0.0023 0.0062
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.003 0.0122
Leishmania major cytochrome p450-like protein 0.002 0.0026 0.0076
Brugia malayi MH1 domain containing protein 0.0014 0.0008 0.0011
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0019 0.0023 0.0093
Echinococcus granulosus tar DNA binding protein 0.0051 0.0114 0.0459
Toxoplasma gondii heat shock protein 90, putative 0.0046 0.0099 0.0337
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0024 0.0036 0.0145
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0023 0.0035 0.0109
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.003 0.0048
Plasmodium falciparum DNA gyrase subunit B 0.0115 0.0299 0.1078
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.003 0.0048
Brugia malayi 2Fe-2S iron-sulfur cluster binding domain containing protein 0.0015 0.001 0.0014
Echinococcus multilocularis heat shock protein 90 0.0046 0.0099 0.0156
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0273 0.0752 0.5893
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.002 0.0026 0.0345
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.002 0.0026 0.0159
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0094 0.0239 0.4027
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0024 0.0036 0.0292
Echinococcus multilocularis 0.002 0.0026 0.0042
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.002 0.0026 0.0159
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0014 0.0009 0.0039
Trichomonas vaginalis glutaminase, putative 0.0401 0.1118 0.8777
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.002 0.0026 0.0159
Brugia malayi Melatonin receptor type 1A 0.0022 0.003 0.0042
Toxoplasma gondii ferredoxin, putative 0.0015 0.001 0.0009
Plasmodium falciparum metacaspase 1 0.0072 0.0174 0.0617
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0045 0.0096 0.0334
Echinococcus multilocularis neuropeptides capa receptor 0.0022 0.003 0.0048
Plasmodium vivax telomerase reverse transcriptase, putative 0.0956 0.2708 1
Brugia malayi Flap endonuclease-1 0.0047 0.0103 0.0142
Trypanosoma brucei DNA topoisomerase IA, putative 0.0018 0.0019 0.005
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.0071
Echinococcus multilocularis musashi 0.005 0.0111 0.0176
Brugia malayi cytochrome P450 0.002 0.0026 0.0036
Echinococcus granulosus 7TM GPCR rhodopsin 0.0022 0.003 0.0122
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0242 0.0661 0.1048
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0022 0.0031 0.0197
Echinococcus granulosus tumor protein p63 0.0296 0.0816 0.3298
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0215 0.0583 1
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0273 0.0752 0.3012
Loa Loa (eye worm) hypothetical protein 0.0106 0.0273 0.2231
Echinococcus multilocularis bloom syndrome protein 0.0098 0.0248 0.0393
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.003 0.0122
Schistosoma mansoni cellular tumor antigen P53 0.0043 0.0092 0.0594
Trypanosoma brucei DNA polymerase eta, putative 0.0014 0.0007 0.0004
Echinococcus granulosus RUN 0.0015 0.001 0.0042
Echinococcus multilocularis lipoxygenase domain containing protein 0.0015 0.001 0.0017
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0014 0.0009 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0052 0.0384
Onchocerca volvulus 0.0022 0.003 0.003
Echinococcus multilocularis Adrenodoxin, mitochondrial 0.0015 0.001 0.0016
Echinococcus granulosus sex peptide receptor 0.0022 0.003 0.0122
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0034 0.0066 0.0223
Echinococcus multilocularis lipoxygenase domain containing protein 0.0015 0.001 0.0017
Loa Loa (eye worm) TOPoisomerase family member 0.0242 0.0661 0.54
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0273 0.0752 0.5893
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0072 0.0174 0.1347
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0067 0.0505
Trypanosoma cruzi metacaspase 5, putative 0.0072 0.0174 0.0623
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.003 0.0048
Plasmodium falciparum histone deacetylase 1 0.0077 0.0188 0.067
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.003 0.0054 0.0171
Loa Loa (eye worm) heat shock protein 90 0.0046 0.0099 0.0805
Trichomonas vaginalis sugar transporter, putative 0.0018 0.002 0.0131
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0019 0.0023 0.0124
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0018 0.0021 0.0243
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0135 0.0355 0.3121
Schistosoma mansoni terminal deoxycytidyl transferase 0.0014 0.0007 0.0044
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0051 0.0168
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0019 0.0023 0.0124
Loa Loa (eye worm) neuropeptide F receptor 0.0022 0.003 0.0246
Trypanosoma brucei glucose transporter, putative 0.0035 0.0067 0.0227
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Entamoeba histolytica acyl-coA synthetase, putative 0.0019 0.0023 0.0063
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0072 0.0174 0.0617
Trichomonas vaginalis endoplasmin, putative 0.0032 0.0061 0.0453
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0022 0.003 0.0048
Loa Loa (eye worm) RecQ helicase 0.0098 0.0248 0.2025
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0022 0.0031 0.0091
Brugia malayi Sugar transporter family protein 0.0102 0.0261 0.0359
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0106 0.0866
Schistosoma mansoni loxhd1 0.0015 0.001 0.0067
Entamoeba histolytica DNA topoisomerase II, putative 0.0242 0.0661 0.2647
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0028 0.0048 0.0358
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0022 0.003 0.0048
Echinococcus multilocularis GPCR, family 2 0.004 0.0082 0.013
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0034 0.0066 0.0223
Echinococcus granulosus transcription factor eb 0.0114 0.0294 0.1189
Entamoeba histolytica acyl-CoA synthetase, putative 0.0019 0.0023 0.0063
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.003 0.0194
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0161
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0039 0.0081 0.0277
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0039 0.0081 0.0299
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0062 0.0145 0.0587
Loa Loa (eye worm) hypothetical protein 0.0018 0.0021 0.0168
Toxoplasma gondii histone deacetylase HDAC4 0.0022 0.0031 0.0086
Trypanosoma brucei histone deacetylase 2 0.0022 0.0031 0.0093
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0018 0.0019 0.0128
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0022 0.003 0.0194
Chlamydia trachomatis DNA gyrase subunit A 0.0047 0.0102 0.2962
Loa Loa (eye worm) flap endonuclease-1 0.0047 0.0103 0.0843
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.019 0.0513 0.0813
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.003 0.0194
Echinococcus granulosus General substrate transporter 0.0084 0.0209 0.0844
Echinococcus granulosus Sugar transporter ERD6 protein 0.0018 0.002 0.008
Brugia malayi histone deacetylase 1 (HD1) 0.0077 0.0188 0.026
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.002 0.0026 0.0159
Onchocerca volvulus 0.0018 0.002 0.002
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0045 0.0096 0.0334
Trichomonas vaginalis aldehyde oxidase, putative 0.0455 0.1273 1
Trypanosoma brucei cytochrome P450, putative 0.0028 0.0048 0.0157
Brugia malayi ORL1-like opioid receptor 0.0022 0.003 0.0042
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0105 0.0269 0.4551
Trypanosoma brucei glucose transporter, putative 0.0035 0.0067 0.0227
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0018 0.0021 0.0106
Echinococcus granulosus neuropeptide Y receptor 0.0022 0.003 0.0122
Treponema pallidum ATP-dependent DNA helicase 0.0037 0.0074 0.0878
Brugia malayi GnHR receptor homolog 0.0022 0.003 0.0042
Plasmodium vivax ferredoxin, putative 0.0015 0.001 0.0009
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0134 0.0351 0.5968
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.003 0.0048
Schistosoma mansoni biogenic amine receptor 0.0022 0.003 0.0194
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0073 0.0177 0.0714
Echinococcus granulosus histone deacetylase 6 0.0022 0.0031 0.0125
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0039 0.0081 0.0277
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0184
Treponema pallidum fructose-bisphosphate aldolase 0.0273 0.0752 1
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.002 0.0026 0.0345
Onchocerca volvulus 0.0015 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0041 0.0085 0.0695
Toxoplasma gondii sugar transporter ST2 0.0018 0.002 0.0045
Toxoplasma gondii target of rapamycin (TOR), putative 0.0029 0.0052 0.0164
Trypanosoma brucei THT1 - hexose transporter, putative 0.0035 0.0067 0.0227
Brugia malayi GRF zinc finger family protein 0.0018 0.0019 0.0027
Brugia malayi Major Facilitator Superfamily protein 0.0018 0.002 0.0027
Trichomonas vaginalis glucose transporter, putative 0.0035 0.0067 0.0505
Loa Loa (eye worm) hypothetical protein 0.0025 0.0038 0.0313
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0018 0.0019 0.005
Loa Loa (eye worm) hypothetical protein 0.0277 0.0762 0.6221
Toxoplasma gondii histone deacetylase HDAC3 0.0077 0.0188 0.067
Trichomonas vaginalis mercuric reductase, putative 0.0014 0.0009 0.0048
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0023 0.0277
Trypanosoma cruzi histone deacetylase, putative 0.0022 0.0031 0.0093
Leishmania major heat shock protein 83-1 0.0046 0.0099 0.0343
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Trypanosoma cruzi hexose transporter 0.0035 0.0067 0.0227
Brugia malayi CXXC zinc finger family protein 0.0046 0.0101 0.0139
Echinococcus granulosus histone deacetylase 8 0.0022 0.0031 0.0125
Trypanosoma brucei DNA topoisomerase III, putative 0.0018 0.0019 0.005
Leishmania major DNA topoisomerase ii 0.0224 0.061 0.2236
Plasmodium falciparum protein kinase 6 0.0415 0.1157 0.4257
Brugia malayi cytoplasmic intermediate filament protein 0.0027 0.0045 0.0062
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0029 0.0052 0.0171
Entamoeba histolytica hypothetical protein 0.0249 0.0683 0.2733
Schistosoma mansoni thyroid hormone receptor 0.0024 0.0036 0.023
Entamoeba histolytica acyl-CoA synthetase, putative 0.0019 0.0023 0.0063
Echinococcus multilocularis serotonin receptor 0.0022 0.003 0.0048
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0027 0.0047 0.0152
Trichomonas vaginalis sugar transporter, putative 0.0035 0.0067 0.0505
Brugia malayi hypothetical protein 0.0025 0.004 0.0056
Loa Loa (eye worm) intermediate filament protein 0.005 0.0111 0.0909
Echinococcus multilocularis aryl hydrocarbon receptor 0.0047 0.0102 0.0162
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0014 0.0007 0.0056
Trichomonas vaginalis sugar transporter, putative 0.0018 0.002 0.0131
Schistosoma mansoni alpha-1 adrenergic receptor 0.0022 0.003 0.0194
Schistosoma mansoni rab6-interacting 0.0015 0.001 0.0067
Wolbachia endosymbiont of Brugia malayi ferredoxin 0.0015 0.001 0.0028
Leishmania major heat shock protein 83-1 0.0046 0.0099 0.0343
Trichomonas vaginalis myo inositol monophosphatase, putative 0.003 0.0053 0.0392
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0014 0.0009 0.0012
Schistosoma mansoni hypothetical protein 0.0427 0.1192 0.7673
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0018 0.0019 0.0027
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.0036 0.0057
Loa Loa (eye worm) hypothetical protein 0.005 0.0111 0.0909
Trypanosoma cruzi cytochrome p450-like protein, putative 0.002 0.0026 0.0076
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0022 0.003 0.0194
Mycobacterium tuberculosis Conserved protein 0.0018 0.0021 0.0243
Toxoplasma gondii Hsp90 domain-containing protein 0.0014 0.0008 0.0002
Trichomonas vaginalis DNA helicase recq, putative 0.0078 0.0191 0.1483
Echinococcus granulosus solute carrier family 22 0.0018 0.002 0.008
Loa Loa (eye worm) G-protein coupled receptor 0.0022 0.003 0.0246
Trichomonas vaginalis sugar transporter, putative 0.0018 0.002 0.0131
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0027 0.0047 0.0145
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0024 0.0036 0.0049
Leishmania major lysyl-tRNA synthetase, putative 0.0022 0.0031 0.0091
Loa Loa (eye worm) hypothetical protein 0.0025 0.0038 0.0313
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0115 0.0299 1
Echinococcus granulosus solute carrier family 22 0.0018 0.002 0.008
Echinococcus multilocularis sex peptide receptor 0.0022 0.003 0.0048
Brugia malayi AKH receptor 0.0022 0.003 0.0042
Trichomonas vaginalis sugar transporter, putative 0.0018 0.002 0.0131
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0018 0.0021 0.0054
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.002 0.0026 0.0345
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0029 0.0203
Leishmania major cytochrome p450-like protein 0.002 0.0026 0.0076
Leishmania major heat shock protein 83-1 0.0046 0.0099 0.0343
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0018 0.0021 0.0083
Toxoplasma gondii sugar transporter ST3 0.0018 0.002 0.0045
Trypanosoma brucei heat shock protein, putative 0.0046 0.0099 0.0343
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.0071
Toxoplasma gondii DNA gyrase/topoisomerase IV, A subunit domain-containing protein 0.0047 0.0102 0.0351
Echinococcus multilocularis calcium dependent protein kinase 0.0028 0.0049 0.0077
Echinococcus granulosus histone deacetylase 3 0.0077 0.0188 0.0761
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0027 0.0047 0.0152
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0115 0.0299 0.5066
Trichomonas vaginalis sugar transporter, putative 0.0018 0.002 0.0131
Trypanosoma cruzi trypanothione reductase, putative 0.0041 0.0087 0.0299
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0039 0.0081 0.0277
Loa Loa (eye worm) glutaminase 0.0401 0.1118 0.9126
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0018 0.0021 0.0243
Echinococcus multilocularis histone deacetylase 1 0.0077 0.0188 0.0298
Leishmania major heat shock protein 83-1 0.0046 0.0099 0.0343
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0048 0.0395
Echinococcus multilocularis neuropeptide s receptor 0.0875 0.2475 0.392
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0094 0.0239 0.6621
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0154 0.0409 0.3606
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0025 0.0312
Brugia malayi hypothetical protein 0.0022 0.003 0.0042
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0014 0.0008 0.0052
Brugia malayi hypothetical protein 0.0015 0.001 0.0014
Echinococcus granulosus survival motor neuron protein 1 0.0438 0.1225 0.4948
Trichomonas vaginalis flap endonuclease-1, putative 0.0047 0.0103 0.0788
Schistosoma mansoni growth hormone secretagogue receptor 0.0022 0.003 0.0194
Echinococcus multilocularis neuropeptide receptor 0.0022 0.003 0.0048
Entamoeba histolytica histone deacetylase, putative 0.0077 0.0188 0.0734
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0134 0.0351 1
Brugia malayi nuclear receptor NHR-88 0.0024 0.0036 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0174 0.1347
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0022 0.003 0.0246
Trypanosoma brucei DNA topoisomerase III, putative 0.0018 0.0019 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.003 0.0211
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0174 0.1347
Plasmodium vivax SET domain protein, putative 0.0051 0.0113 0.039
Loa Loa (eye worm) hypothetical protein 0.005 0.011 0.0901
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.003 0.0054 0.044
Trichomonas vaginalis sugar transporter, putative 0.0018 0.002 0.0131
Onchocerca volvulus 0.0051 0.0113 0.0113
Trypanosoma cruzi metacaspase, putative 0.0072 0.0174 0.0623
Echinococcus granulosus lamin dm0 0.005 0.0111 0.045
Echinococcus multilocularis hyperpolarization activated cyclic 0.0012 0.0003 0.0005
Echinococcus granulosus orexin receptor type 2 0.0022 0.003 0.0122
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0016 0.0015 0.0033
Leishmania major protein kinase, putative 0.003 0.0054 0.0177
Brugia malayi hypothetical protein 0.0018 0.002 0.0027
Brugia malayi steroid hormone receptor 0.0024 0.0036 0.0049
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0027 0.0046 0.1276
Loa Loa (eye worm) hypothetical protein 0.0023 0.0035 0.0282
Mycobacterium ulcerans hypothetical protein 0.0019 0.0023 0.0124
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.003 0.0054 0.0085
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0058 0.043
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0038 0.0078 0.0591
Schistosoma mansoni tar DNA-binding protein 0.0051 0.0114 0.0731
Onchocerca volvulus 0.0022 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0245
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.003 0.0122
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0024 0.0036 0.0049
Leishmania major mitochondrial DNA topoisomerase II 0.0233 0.0635 0.233
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.002 0.0026 0.0159
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.004 0.0082 0.0331
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0006 0.0022
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0029 0.0052 0.0072
Trichomonas vaginalis DNA helicase recq, putative 0.0098 0.0248 0.1929
Onchocerca volvulus Bile acid receptor homolog 0.0024 0.0036 0.0036
Onchocerca volvulus 0.005 0.0111 0.0111
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0022 0.003 0.0048
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0052 0.0384
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0027 0.0047 0.0152
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0158 0.0421 0.153
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0161
Onchocerca volvulus Neuropeptide F receptor homolog 0.0022 0.003 0.003
Schistosoma mansoni neuropeptide receptor 0.0022 0.003 0.0194
Brugia malayi follicle stimulating hormone receptor 0.0022 0.003 0.0042
Leishmania major ferredoxin, 2fe-2s-like protein 0.0015 0.001 0.0015
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0019 0.0023 0.0155
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0022 0.003 0.0042
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0022 0.003 0.0122
Echinococcus multilocularis solute carrier family 22 0.0018 0.002 0.0031
Echinococcus granulosus solute carrier family 22 0.0018 0.002 0.008
Brugia malayi hypothetical protein 0.0022 0.003 0.0042
Trichomonas vaginalis sugar transporter, putative 0.0018 0.002 0.0131
Echinococcus granulosus g protein coupled receptor 0.0022 0.003 0.0122
Loa Loa (eye worm) TAR-binding protein 0.0051 0.0114 0.0927
Schistosoma mansoni adenoreceptor 0.0022 0.003 0.0194
Leishmania major hypothetical protein, conserved 0.0103 0.0264 0.0955
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.002 0.0026 0.0159
Brugia malayi major facilitator superfamily protein 0.0018 0.002 0.0027
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.003 0.0122
Echinococcus granulosus neuropeptide s receptor 0.0875 0.2475 1
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0242 0.0661 0.2672
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0052 0.0384
Loa Loa (eye worm) sugar transporter 0.0102 0.0261 0.2127
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0106 0.0683
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0249 0.0683 0.2733
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0106 0.0683
Brugia malayi Smad1 0.0014 0.0008 0.0011
Loa Loa (eye worm) hypothetical protein 0.0178 0.0478 0.3904
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0051 0.0113 0.0729
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0072 0.0174 0.1347
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0318 0.0879 0.3232
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0134 0.0351 0.3084
Trypanosoma cruzi DNA topoisomerase III, putative 0.0018 0.0019 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0102 0.0261 0.2027
Schistosoma mansoni hypothetical protein 0.0022 0.003 0.0194
Plasmodium falciparum thioredoxin reductase 0.0041 0.0087 0.0293
Mycobacterium ulcerans acyl-CoA synthetase 0.0019 0.0023 0.0124
Giardia lamblia Pms1-like protein 0.0018 0.0021 0.0042
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.0261 0.1052
Leishmania major histone deacetylase, putative 0.0022 0.0031 0.0093
Echinococcus multilocularis neuropeptide FF receptor 2 0.0022 0.003 0.0048
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0025 0.004 0.033
Trypanosoma brucei heat shock protein, putative 0.0046 0.0099 0.0343
Schistosoma mansoni hypothetical protein 0.0022 0.003 0.0194
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.0018 0.0021 0.0033
Echinococcus granulosus lipoxygenase domain containing protein 0.0015 0.001 0.0042
Schistosoma mansoni histone deacetylase 0.0077 0.0188 0.1213
Trypanosoma cruzi DNA polymerase eta, putative 0.0014 0.0007 0.0004
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0018 0.002 0.0099
Schistosoma mansoni flap endonuclease-1 0.0043 0.009 0.0581
Schistosoma mansoni smad1 5 8 and 0.0014 0.0008 0.0052
Giardia lamblia Sugar-proton symporter 0.0018 0.002 0.0039
Brugia malayi hypothetical protein 0.0022 0.003 0.0042
Onchocerca volvulus 0.0018 0.002 0.002
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0014 0.0009 0.0006
Toxoplasma gondii histone lysine methyltransferase SET1 0.0045 0.0098 0.0336
Loa Loa (eye worm) hypothetical protein 0.0067 0.016 0.1307
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0022 0.003 0.0042
Echinococcus granulosus intermediate filament protein 0.005 0.0111 0.045
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0015 0.001 0.0015
Trichomonas vaginalis receptor histidine kinase, putative 0.0018 0.0021 0.0137
Plasmodium falciparum thioredoxin reductase 0.0014 0.0009 0.0006
Schistosoma mansoni caspase-3 (C14 family) 0.019 0.0513 0.3303
Brugia malayi sulfakinin receptor protein 0.0022 0.003 0.0042
Leishmania major DNA topoisomerase III, putative 0.0018 0.0019 0.005
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0088 0.0222 0.0351
Echinococcus multilocularis smad 0.0014 0.0008 0.0013
Trypanosoma cruzi adrenodoxin precursor, putative 0.0015 0.001 0.0015
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0224 0.061 0.2236
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0115 0.0299 0.39
Trypanosoma cruzi heat shock protein 85, putative 0.0046 0.0099 0.0343
Brugia malayi glutaminase DH11.1 0.0401 0.1118 0.154
Echinococcus granulosus neuropeptide receptor A26 0.0875 0.2475 1
Mycobacterium tuberculosis Hypothetical oxidoreductase 0.0015 0.001 0.006
Brugia malayi hypothetical protein 0.0178 0.0478 0.0659
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0012 0.0003 0.002
Mycobacterium leprae Possible regulatory protein 0.0022 0.003 0.0317
Loa Loa (eye worm) hypothetical protein 0.0025 0.0038 0.0313
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0014 0.0009 0.0006
Brugia malayi Dopamine receptor protein 1 0.0022 0.003 0.0042
Trichomonas vaginalis histone deacetylase, putative 0.0077 0.0188 0.1459
Schistosoma mansoni protein kinase 0.003 0.0054 0.0347
Toxoplasma gondii adrenodoxin-type ferredoxin, putative 0.0015 0.001 0.0009
Schistosoma mansoni cpg binding protein 0.0048 0.0105 0.0675
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0089 0.0224 0.0309
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.015 0.0399 0.1456
Echinococcus multilocularis caspase 2 0.0139 0.0366 0.058
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0031
Schistosoma mansoni protein kinase 0.003 0.0054 0.0347
Loa Loa (eye worm) hypothetical protein 0.0077 0.0188 0.1538
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0058 0.0134 0.1028
Schistosoma mansoni hypothetical protein 0.004 0.0082 0.0528
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0029 0.0052 0.0083
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0073 0.0177 0.0243
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0022 0.003 0.0042
Leishmania major lanosterol 14-alpha-demethylase, putative 0.002 0.0026 0.0076
Brugia malayi Ets-domain containing protein 0.0058 0.0134 0.0185
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0009 0.0012
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0273 0.0752 0.5893
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0014 0.0009 0.0012
Trypanosoma cruzi metacaspase, putative 0.0072 0.0174 0.0623
Echinococcus multilocularis FTZ F1 alpha 0.0024 0.0036 0.0057
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.003 0.0048
Brugia malayi Disco-interacting protein 2 homolog 0.0027 0.0045 0.0062
Brugia malayi Intermediate filament tail domain containing protein 0.005 0.0111 0.0153
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0039 0.0081 0.0521
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0022 0.003 0.0122
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0273 0.0752 0.5893
Echinococcus granulosus dna polymerase eta 0.0014 0.0007 0.0028
Plasmodium falciparum DNA topoisomerase 2 0.0242 0.0661 0.2421
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.003 0.0053 0.151
Leishmania major mitochondrial DNA polymerase beta 0.0318 0.0879 0.3232
Loa Loa (eye worm) MH2 domain-containing protein 0.0205 0.0556 0.454
Trichomonas vaginalis Ferredoxin 4 0.0015 0.001 0.0054
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0024 0.0036 0.0049
Trichomonas vaginalis histone deacetylase, putative 0.0077 0.0188 0.1459
Schistosoma mansoni biogenic amine (5HT) receptor 0.0022 0.003 0.0194
Onchocerca volvulus 0.0022 0.003 0.003
Entamoeba histolytica myo-inositol monophosphatase, putative 0.003 0.0053 0.0186
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0037 0.0074 0.0247
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.003 0.0054 0.0171
Echinococcus granulosus hyperpolarization activated cyclic 0.0012 0.0003 0.0013
Trichomonas vaginalis heat shock protein, putative 0.0046 0.0099 0.0752
Chlamydia trachomatis DNA gyrase subunit B 0.0124 0.0325 1
Echinococcus multilocularis ferredoxin adrenodoxin 0.0015 0.001 0.0016
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0022 0.003 0.0246
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.002 0.0026 0.0159
Loa Loa (eye worm) neuropeptide F receptor 0.0022 0.003 0.0246
Leishmania major protein kinase, putative 0.0032 0.0059 0.0196
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0022 0.003 0.0089
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0027 0.0047 0.0189
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0014 0.0009 0.0004
Trypanosoma cruzi histone deacetylase, putative 0.0022 0.0031 0.0093
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0088 0.0222 0.0895
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0018 0.0019 0.0125
Schistosoma mansoni hypothetical protein 0.0427 0.1192 0.7673
Plasmodium falciparum histone deacetylase, putative 0.0022 0.0031 0.0086
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0022 0.003 0.0048
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0019 0.0021 0.0052
Leishmania major hypothetical protein, conserved 0.0015 0.001 0.0015
Plasmodium vivax proline--tRNA ligase, putative 0.0034 0.0066 0.0216
Loa Loa (eye worm) MH1 domain-containing protein 0.0014 0.0008 0.0066
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.002 0.0026 0.0345
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0024 0.0036 0.0292
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0024 0.0036 0.0145
Onchocerca volvulus Adrenodoxin, mitochondrial homolog 0.0015 0.001 0.001
Plasmodium vivax calcium-dependent protein kinase, putative 0.003 0.0054 0.0171
Onchocerca volvulus 0.0089 0.0224 0.0224
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0024 0.0036 0.0057
Trypanosoma cruzi trypanothione reductase, putative 0.0014 0.0009 0.0012
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0018 0.002 0.0364
Plasmodium falciparum histone deacetylase 2 0.0022 0.0031 0.0086
Brugia malayi Telomerase reverse transcriptase 0.2544 0.726 1
Echinococcus granulosus dna polymerase kappa 0.0038 0.0078 0.0316
Echinococcus multilocularis apoptotic protease activating factor 1 0.0067 0.016 0.0253
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.002 0.0026 0.0076
Onchocerca volvulus 0.0018 0.002 0.002
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0029 0.0052 0.0171
Loa Loa (eye worm) hypoxia-induced factor 1 0.0132 0.0346 0.2825
Trichomonas vaginalis histone deacetylase, putative 0.0077 0.0188 0.1459
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0012 0.0003 0.0013
Schistosoma mansoni glucose transporter 0.0018 0.002 0.0127
Schistosoma mansoni lamin 0.005 0.0111 0.0717
Onchocerca volvulus 0.0022 0.003 0.003
Brugia malayi histone deacetylase 3 (HD3) 0.0077 0.0188 0.026
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0018 0.002 0.0127
Giardia lamblia Hexose transporter 0.0018 0.002 0.0039
Brugia malayi lysyl-tRNA synthetase 0.0022 0.0031 0.0042
Plasmodium vivax endoplasmin, putative 0.0046 0.0099 0.0337
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0018 0.002 0.0229
Mycobacterium tuberculosis Conserved hypothetical protein 0.0167 0.0448 0.7654
Plasmodium falciparum metacaspase-like protein 0.0072 0.0174 0.0617
Loa Loa (eye worm) melatonin receptor type 1A 0.0022 0.003 0.0246
Echinococcus multilocularis DNA methyltransferase 2, putative 0.0014 0.0008 0.0012
Onchocerca volvulus 0.0022 0.003 0.003
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0122 0.0318 0.0504
Echinococcus multilocularis histone deacetylase 6 0.0022 0.0031 0.0049
Schistosoma mansoni hypothetical protein 0.004 0.0082 0.0528
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0022 0.003 0.0048
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.002 0.0026 0.0159
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0009 0.0012
Mycobacterium ulcerans putative regultory protein 0.0018 0.0021 0.0106
Loa Loa (eye worm) glutaminase 2 0.0401 0.1118 0.9126
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0029 0.0052 0.0335
Trichomonas vaginalis Ferredoxin 1 0.0015 0.001 0.0054
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0096 0.0334
Echinococcus granulosus cytochrome P450 2K1 0.002 0.0026 0.0107
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0012 0.0003 0.002
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0014 0.0007 0.0028
Plasmodium falciparum ferredoxin, putative 0.0015 0.001 0.0009
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0078 0.0191 0.0687
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0018 0.0021 0.0106
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0027 0.0044 0.065
Echinococcus multilocularis histone deacetylase 0.0022 0.0031 0.0049
Loa Loa (eye worm) hypothetical protein 0.0024 0.0036 0.0292
Trichomonas vaginalis sugar transporter, putative 0.0018 0.002 0.0131
Trypanosoma cruzi heat shock protein 85, putative 0.0046 0.0099 0.0343
Onchocerca volvulus 0.0015 0.001 0.001
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0077 0.0188 0.1459
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.002 0.0131
Echinococcus multilocularis transcription factor eb 0.0114 0.0294 0.0466
Mycobacterium tuberculosis Conserved hypothetical protein 0.0014 0.0007 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0035 0.0249
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0018 0.002 0.0045
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0018 0.0021 0.0106
Echinococcus granulosus histone deacetylase 6 0.0022 0.0031 0.0125
Loa Loa (eye worm) hypothetical protein 0.0023 0.0035 0.0282
Brugia malayi Latrophilin receptor protein 2 0.004 0.0082 0.0113
Leishmania major heat shock protein 83-1 0.0046 0.0099 0.0343
Brugia malayi Nuclear hormone receptor-like 1 0.0024 0.0036 0.0049
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0078 0.0191 0.0687
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0022 0.003 0.0194
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0012 0.0003 0.0013
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0051 0.0113 0.0727
Plasmodium falciparum ataxin-2 like protein, putative 0.0103 0.0264 0.0949
Mycobacterium ulcerans sugar transporter 0.0018 0.002 0.0099
Onchocerca volvulus 0.0015 0.001 0.001
Loa Loa (eye worm) steroid hormone receptor 0.0024 0.0036 0.0292
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0051 0.0113 0.039
Schistosoma mansoni amine GPCR 0.0022 0.003 0.0194
Onchocerca volvulus 0.0022 0.003 0.003
Trypanosoma brucei metacaspase MCA3 0.0072 0.0174 0.0623
Onchocerca volvulus 0.0046 0.01 0.01
Trichomonas vaginalis sugar transporter, putative 0.0018 0.002 0.0131
Trypanosoma brucei heat shock protein, putative 0.0046 0.0099 0.0343
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0018 0.0021 0.0137
Loa Loa (eye worm) histone deacetylase 11 0.0022 0.0031 0.0252
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0273 0.0752 0.5893
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Schistosoma mansoni sugar transporter 0.0018 0.002 0.0127
Echinococcus granulosus dro:myosuppressin receptor 0.0022 0.003 0.0122
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0018 0.0021 0.0048
Loa Loa (eye worm) inositol-1 0.003 0.0053 0.0432
Echinococcus granulosus geminin 0.0427 0.1192 0.4816
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0067 0.0505
Loa Loa (eye worm) hypothetical protein 0.004 0.0082 0.0669
Loa Loa (eye worm) hypothetical protein 0.0049 0.0109 0.0888
Trypanosoma brucei glucose transporter, putative 0.0035 0.0067 0.0227
Mycobacterium ulcerans DNA topoisomerase I 0.0018 0.0019 0.0096
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0014 0.0009 0.0012
Echinococcus granulosus flap endonuclease 1 0.0047 0.0103 0.0417
Trichomonas vaginalis sugar transporter, putative 0.0018 0.002 0.0131
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0039 0.0081 0.0277
Entamoeba histolytica recQ family helicase, putative 0.0036 0.007 0.0257
Leishmania major 4-coumarate:coa ligase-like protein 0.0019 0.0023 0.0062
Trypanosoma brucei metacaspase 5, putative 0.0072 0.0174 0.0623
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0057 0.0131 0.0457
Plasmodium vivax DNA topoisomerase II, putative 0.0242 0.0661 0.2421
Loa Loa (eye worm) hypothetical protein 0.0024 0.0036 0.0292
Onchocerca volvulus 0.0022 0.003 0.003
Schistosoma mansoni hypothetical protein 0.0067 0.016 0.103
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0014 0.0009 0.0059
Mycobacterium leprae Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) 0.0032 0.0059 0.1201
Loa Loa (eye worm) hepatopoietin HPO2 0.0027 0.0047 0.0383
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0018 0.002 0.0031
Mycobacterium ulcerans integral membrane transport protein 0.0018 0.002 0.0099
Plasmodium falciparum endoplasmin, putative 0.0032 0.0061 0.0197
Trichomonas vaginalis glutathione reductase, putative 0.0014 0.0009 0.0048
Echinococcus multilocularis lamin dm0 0.005 0.0111 0.0176
Toxoplasma gondii RNA-directed DNA polymerase 0.0956 0.2708 1
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0115 0.0299 0.1078
Loa Loa (eye worm) hypothetical protein 0.0037 0.0074 0.0607
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0013 0.0006 0.0009
Brugia malayi Histone deacetylase family protein 0.0022 0.0031 0.0043
Schistosoma mansoni lipoxygenase 0.0062 0.0145 0.0935
Entamoeba histolytica recQ family helicase, putative 0.0078 0.0191 0.0747
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0087 0.0217 0.188
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0014 0.0008 0.0008
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.002 0.0026 0.0345
Schistosoma mansoni hypothetical protein 0.004 0.0082 0.0528
Echinococcus granulosus microtubule associated protein 2 0.0553 0.1554 0.6276
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0018 0.0021 0.0054
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.004 0.0082 0.013
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0018 0.0021 0.0137
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0037 0.0074 0.0254
Schistosoma mansoni amine GPCR 0.0022 0.003 0.0194
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0078 0.0267
Plasmodium falciparum proline--tRNA ligase 0.0034 0.0066 0.0216
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.0261 0.1052
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.002 0.0026 0.0345
Leishmania major cytochrome p450-like protein 0.0028 0.0048 0.0157
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0019 0.0023 0.0277
Brugia malayi ImpB/MucB/SamB family protein 0.0014 0.0007 0.0009
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0022 0.0031 0.0091
Plasmodium vivax heat shock protein 90, putative 0.0014 0.0008 0.0002
Plasmodium vivax thioredoxin reductase, putative 0.0041 0.0087 0.0293
Trypanosoma cruzi Heat shock protein 83, putative 0.0046 0.0099 0.0343
Echinococcus multilocularis General substrate transporter 0.0084 0.0209 0.0331
Mycobacterium tuberculosis Probable oxidoreductase 0.0015 0.001 0.006
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0105 0.0269 0.4551
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0018 0.0021 0.0137
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0018 0.0019 0.0031
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0024 0.0036 0.0049
Trypanosoma cruzi adrenodoxin precursor, putative 0.0015 0.001 0.0015
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.003 0.0053 0.0174
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.0036 0.0145
Schistosoma mansoni gabp alpha 0.0058 0.0134 0.0865
Treponema pallidum quinoline 2-oxidoreductase 0.0072 0.0175 0.2237
Brugia malayi Endoplasmin precursor 0.0046 0.0099 0.0136
Loa Loa (eye worm) Smad1 0.0014 0.0008 0.0066
Trypanosoma brucei heat shock protein 90, putative 0.0046 0.0099 0.0343
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.003 0.0054 0.0171
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.0036 0.0145
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0006 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0078 0.0267
Echinococcus granulosus apoptotic protease activating factor 1 0.0067 0.016 0.0647
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0078 0.0267
Trichomonas vaginalis sugar transporter, putative 0.0018 0.002 0.0131
Brugia malayi hypothetical protein 0.0018 0.002 0.0027
Loa Loa (eye worm) isocitrate dehydrogenase 0.0029 0.0052 0.0425
Echinococcus multilocularis Smad4 0.0014 0.0008 0.0013
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0018 0.0021 0.0243
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0039 0.0081 0.0277
Brugia malayi Cytochrome P450 family protein 0.0051 0.0115 0.0159
Brugia malayi MH2 domain containing protein 0.0205 0.0556 0.0766
Trypanosoma cruzi heat shock protein 85, putative 0.0046 0.0099 0.0343
Echinococcus granulosus ecdysone induced protein 78C 0.0024 0.0036 0.0145
Echinococcus multilocularis cpg binding protein 0.0048 0.0105 0.0166
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0018 0.002 0.0051
Trypanosoma cruzi cytochrome P450, putative 0.0028 0.0048 0.0157
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0014 0.0009 0.0006
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0159
Giardia lamblia Flap structure-specific endonuclease 0.0047 0.0103 0.0348
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0062 0.0145 0.023
Loa Loa (eye worm) phosphatidylinositol 3 0.0013 0.0006 0.0048
Echinococcus multilocularis caspase 8 0.0072 0.0174 0.0276
Giardia lamblia DNA topoisomerase II 0.0224 0.0609 0.2222
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0018 0.002 0.0229
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0318 0.0879 0.3232
Plasmodium vivax glutathione reductase, putative 0.0041 0.0087 0.0293
Trypanosoma brucei heat shock protein, putative 0.0046 0.0099 0.0343
Brugia malayi Cytochrome P450 family protein 0.0028 0.0048 0.0067
Plasmodium falciparum hexose transporter 0.0102 0.0261 0.0937
Schistosoma mansoni disco-interacting protein 2 (dip2) 0.0028 0.0047 0.0305
Brugia malayi heat shock protein 90 0.0046 0.0099 0.0136
Mycobacterium ulcerans electron transfer protein 0.0015 0.001 0.0011
Echinococcus granulosus caspase 3 0.0118 0.0307 0.124
Loa Loa (eye worm) hypothetical protein 0.0157 0.0418 0.3416
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0031 0.0058 0.0192
Plasmodium vivax heat shock protein 86, putative 0.0046 0.0099 0.0337
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.003 0.0054 0.0177
Schistosoma mansoni Smad4 0.0014 0.0008 0.0052
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.002 0.0026 0.0159
Trypanosoma brucei heat shock protein, putative 0.0046 0.0099 0.0343
Mycobacterium ulcerans DNA polymerase IV 0.0038 0.0078 0.0626
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0029 0.0052 0.0165
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0014 0.0009 0.0012
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0078 0.0267
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0004 0.0005
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0018 0.0021 0.0243
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0014 0.0009 0.0004
Brugia malayi hypothetical protein 0.0022 0.003 0.0042
Trichomonas vaginalis sugar transporter, putative 0.0018 0.002 0.0131
Mycobacterium ulcerans DNA gyrase subunit B 0.0115 0.0299 0.2615
Trichomonas vaginalis sugar transporter, putative 0.0018 0.002 0.0131
Trichomonas vaginalis heat shock protein, putative 0.0027 0.0046 0.0339
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0012 0.0004 0.0006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0024 0.0036 0.0292
Schistosoma mansoni neuropeptide f receptor 76f 0.0022 0.003 0.0194
Chlamydia trachomatis DNA gyrase subunit A 0.0047 0.0102 0.2962
Trypanosoma brucei glucose transporter 2A 0.0035 0.0067 0.0227
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0031 0.0057 0.0078
Trypanosoma cruzi hexose transporter, putative 0.0035 0.0067 0.0227
Brugia malayi latrophilin 2 splice variant baaae 0.0086 0.0214 0.0295
Echinococcus granulosus neuropeptide receptor 0.0022 0.003 0.0122
Loa Loa (eye worm) hypothetical protein 0.0126 0.0328 0.2679
Echinococcus granulosus histone deacetylase 6 0.0022 0.0031 0.0125
Trichomonas vaginalis sugar transporter, putative 0.0018 0.002 0.0131
Schistosoma mansoni voltage-gated potassium channel 0.0012 0.0003 0.002
Schistosoma mansoni glucose transport protein 0.0102 0.0261 0.1677
Mycobacterium leprae Probable two component sensor kinase MprB 0.0018 0.0021 0.0033
Trichomonas vaginalis sugar transporter, putative 0.0018 0.002 0.0131
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0025 0.004 0.0056
Plasmodium falciparum telomerase reverse transcriptase 0.0956 0.2708 1
Brugia malayi ecdysteroid receptor 0.0024 0.0036 0.0049
Schistosoma mansoni adrenodoxin 0.0015 0.001 0.0064
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0024 0.0036 0.0049
Brugia malayi isocitrate dehydrogenase 0.0029 0.0052 0.0072
Echinococcus granulosus cpg binding protein 0.0048 0.0105 0.0424
Onchocerca volvulus Putative transporter 0.0018 0.002 0.002
Mycobacterium tuberculosis Possible electron transfer protein FdxB 0.0015 0.001 0.006
Brugia malayi Cytochrome P450 family protein 0.0028 0.0048 0.0067
Trypanosoma cruzi heat shock protein, putative 0.0014 0.0008 0.0009
Treponema pallidum heat shock protein 90 0.0027 0.0046 0.0498
Echinococcus multilocularis neuropeptide receptor 0.0022 0.003 0.0048
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0022 0.003 0.0194
Plasmodium falciparum DNA topoisomerase 3, putative 0.0018 0.0019 0.0044
Loa Loa (eye worm) histone deacetylase 7A 0.0022 0.0031 0.0252
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Plasmodium falciparum LCCL domain-containing protein 0.0015 0.001 0.0011
Trypanosoma cruzi metacaspase 5, putative 0.0072 0.0174 0.0623
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0012 0.0024
Echinococcus multilocularis tar DNA binding protein 0.0051 0.0114 0.018
Echinococcus multilocularis caspase 0.019 0.0513 0.0813
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0027 0.0045 0.0366
Schistosoma mansoni histone deacetylase 4 5 0.0022 0.0031 0.0199
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0224 0.061 0.2236
Trypanosoma brucei sugar transporter, putative 0.0018 0.002 0.0051
Entamoeba histolytica Flap nuclease, putative 0.0047 0.0103 0.039
Trypanosoma brucei electron transfer protein, putative 0.0015 0.001 0.0015
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.015 0.0399 0.1456
Brugia malayi Histone deacetylase 1 0.0077 0.0188 0.026
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.035 0.097 0.7921
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0078 0.0267
Mycobacterium ulcerans electron transfer protein FdxB 0.0015 0.001 0.0011
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0171 0.0459 0.0459
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0027 0.0047 0.0152
Trichomonas vaginalis sugar transporter, putative 0.0018 0.002 0.0131
Schistosoma mansoni blooms syndrome DNA helicase 0.0061 0.0142 0.0912
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0027 0.0044 0.0742
Echinococcus granulosus Smad4 0.0014 0.0008 0.0033
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Echinococcus multilocularis allatostatin A receptor 0.0022 0.003 0.0048
Trypanosoma brucei histone deacetylase 3 0.0022 0.0031 0.0093
Brugia malayi Cytochrome P450 family protein 0.002 0.0026 0.0036
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0106 0.0146
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0013 0.0006 0.0008
Schistosoma mansoni steroid hormone receptor ad4bp 0.0024 0.0036 0.023
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.002 0.0026 0.0345
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0066 0.0158 0.0611
Brugia malayi PAS domain containing protein 0.0053 0.012 0.0166
Onchocerca volvulus 0.0022 0.003 0.003
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0027 0.0047 0.0074
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0085
Echinococcus multilocularis solute carrier family 22 0.0018 0.002 0.0031
Entamoeba histolytica hypothetical protein 0.0122 0.0318 0.126
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.002 0.0026 0.0345
Chlamydia trachomatis DNA gyrase subunit B 0.0115 0.0299 0.9179
Leishmania major DNA topoisomerase III, putative 0.0018 0.0019 0.005
Loa Loa (eye worm) hypothetical protein 0.0041 0.0085 0.0695
Brugia malayi putative neuropeptide receptor NPR1 0.0022 0.003 0.0042
Schistosoma mansoni RAR-like nuclear receptor 0.0024 0.0036 0.023
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0051 0.0113 0.0727
Echinococcus multilocularis lamin 0.005 0.0111 0.0176
Schistosoma mansoni cpg binding protein 0.0046 0.0101 0.0651
Mycobacterium tuberculosis DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0047 0.0102 0.1661
Brugia malayi RE15519p 0.0022 0.003 0.0042
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0015 0.001 0.0015
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0077 0.0188 0.1459
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.0261 0.1052
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.002 0.0026 0.0345
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.003 0.0054 0.044
Echinococcus multilocularis histone deacetylase 6 0.0022 0.0031 0.0049
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.003 0.0048
Leishmania major heat shock protein 83-1 0.0046 0.0099 0.0343
Loa Loa (eye worm) hypothetical protein 0.0025 0.0038 0.0313
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.002 0.0026 0.0345
Brugia malayi hypoxia-induced factor 1 0.0132 0.0346 0.0477
Toxoplasma gondii isocitrate dehydrogenase 0.0029 0.0052 0.0165
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0022 0.003 0.0122
Brugia malayi major facilitator superfamily protein 0.0018 0.002 0.0027
Leishmania major heat shock protein 83-1 0.0046 0.0099 0.0343
Loa Loa (eye worm) hypothetical protein 0.0139 0.0366 0.299
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0024 0.0036 0.023
Schistosoma mansoni rab6-interacting 0.0015 0.001 0.0067
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.002 0.0026 0.0345
Brugia malayi hypothetical protein 0.0022 0.003 0.0042
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0024 0.0036 0.0292
Echinococcus multilocularis inositol monophosphatase 1 0.003 0.0053 0.0084
Echinococcus multilocularis somatostatin receptor 0.0022 0.003 0.0048
Echinococcus granulosus smad 0.0014 0.0008 0.0033
Trypanosoma cruzi heat shock protein 85, putative 0.0027 0.0046 0.0149
Trichomonas vaginalis sugar transporter, putative 0.0018 0.002 0.0131
Trypanosoma brucei histone deacetylase 4 0.0022 0.0031 0.0093
Brugia malayi bHLH-PAS transcription factor 0.0032 0.0058 0.008
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.002 0.0026 0.0159
Schistosoma mansoni heat shock protein 0.0014 0.0008 0.0053
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0077 0.0188 0.1459
Loa Loa (eye worm) histone deacetylase 3 0.0077 0.0188 0.1538
Echinococcus granulosus caspase 8 0.0072 0.0174 0.0704
Trichomonas vaginalis sugar transport protein, putative 0.0018 0.002 0.0131
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0058 0.043
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0022 0.003 0.0122
Plasmodium vivax multidomain scavenger receptor, putative 0.0015 0.001 0.0011
Trypanosoma brucei Heat shock protein 83, putative 0.0046 0.0099 0.0343
Brugia malayi Pre-SET motif family protein 0.0051 0.0113 0.0156
Brugia malayi hypothetical protein 0.0022 0.003 0.0042
Schistosoma mansoni opsin-like receptor 0.0022 0.003 0.0194
Trichomonas vaginalis sugar transporter, putative 0.0018 0.002 0.0131
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0009 0.0012
Loa Loa (eye worm) MH2 domain-containing protein 0.0014 0.0008 0.0066
Echinococcus multilocularis heat shock protein 0.0046 0.0099 0.0156
Onchocerca volvulus 0.0018 0.002 0.002
Giardia lamblia Heat shock protein HSP 90-alpha 0.0046 0.0099 0.0331
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.003 0.0194
Echinococcus granulosus aryl hydrocarbon receptor 0.0047 0.0102 0.0413
Plasmodium falciparum calcium-dependent protein kinase 2 0.003 0.0054 0.0171
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0023 0.0035 0.0109
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0161
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.002 0.0131
Brugia malayi Thioredoxin reductase 0.0041 0.0087 0.012
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0012 0.0003 0.002
Plasmodium vivax hypothetical protein, conserved 0.0018 0.0021 0.0048
Echinococcus multilocularis G protein coupled receptor 139 0.0022 0.003 0.0048
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0036 0.007 0.0232
Plasmodium falciparum glutathione reductase 0.0014 0.0009 0.0006
Echinococcus multilocularis caspase 3 0.0118 0.0307 0.0486
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Echinococcus granulosus heat shock protein 90 0.0027 0.0046 0.0186
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0024 0.0036 0.0292
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0024 0.0037 0.015
Brugia malayi Sugar transporter family protein 0.0018 0.002 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0029 0.0203
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.0018 0.0021 0.0033
Echinococcus multilocularis orexin receptor type 2 0.0022 0.003 0.0048
Schistosoma mansoni neuropeptide F-like receptor 0.0022 0.003 0.0194
Leishmania major heat shock protein 83-1 0.0046 0.0099 0.0343
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0078 0.0267
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.002 0.0026 0.0345
Trichomonas vaginalis heat shock protein, putative 0.0027 0.0046 0.0339
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0055 0.0127 0.0442
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.002 0.0026 0.0345
Trichomonas vaginalis inositol monophosphatase, putative 0.003 0.0053 0.0392
Loa Loa (eye worm) hypothetical protein 0.0113 0.0292 0.2385
Brugia malayi neuropeptide F receptor 0.0022 0.003 0.0042
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0078 0.0267
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.003 0.0054 0.0171
Echinococcus multilocularis muscleblind protein 0.0277 0.0762 0.1207
Entamoeba histolytica heat shock protein 90, putative 0.0046 0.0099 0.0371
Giardia lamblia Grp94/Hsp90 0.0027 0.0046 0.0137
Loa Loa (eye worm) major facilitator superfamily transporter 0.0018 0.002 0.0161
Loa Loa (eye worm) hypothetical protein 0.0024 0.0037 0.0304
Leishmania major heat shock protein 83-1 0.0046 0.0099 0.0343
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0273 0.0752 0.5893
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Brugia malayi Pre-SET motif family protein 0.035 0.097 0.1336
Schistosoma mansoni histone deacetylase hda2 0.0022 0.0031 0.0199
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0171 0.0459 0.0459
Entamoeba histolytica heat shock protein 90, putative 0.0046 0.0099 0.0371
Loa Loa (eye worm) hypothetical protein 0.0024 0.0036 0.0292
Onchocerca volvulus 0.0043 0.0092 0.0092
Echinococcus granulosus allatostatin A receptor 0.0022 0.003 0.0122
Brugia malayi hypothetical protein 0.0018 0.002 0.0027
Leishmania major histone deacetylase, putative 0.0077 0.0188 0.0676
Echinococcus multilocularis GA binding protein alpha chain 0.0058 0.0134 0.0213
Schistosoma mansoni DNA topoisomerase II 0.0242 0.0661 0.4257
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0018 0.0021 0.0033
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.002 0.0026 0.0159
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0081 0.0612
Trypanosoma brucei Metacaspase-4 0.0072 0.0174 0.0623
Loa Loa (eye worm) hypothetical protein 0.0158 0.0422 0.3444
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0012 0.0024
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0106 0.0429
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0161
Plasmodium vivax DNA topoisomerase 3, putative 0.0018 0.0019 0.0044
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0012 0.0003 0.002
Echinococcus multilocularis g protein coupled receptor 0.0022 0.003 0.0048
Plasmodium vivax lysine--tRNA ligase, putative 0.0022 0.0031 0.0085
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.003 0.0053 0.0168
Brugia malayi hypothetical protein 0.0022 0.003 0.0042
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.002 0.0026 0.0159
Brugia malayi Probable DNA topoisomerase II 0.0242 0.0661 0.0911
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.003 0.0054 0.0218
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0014 0.0009 0.0012
Echinococcus multilocularis neuropeptide Y receptor 0.0022 0.003 0.0048
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Trichomonas vaginalis sugar transporter, putative 0.0018 0.002 0.0131
Onchocerca volvulus 0.0398 0.1108 0.1108
Echinococcus multilocularis thioredoxin glutathione reductase 0.0041 0.0087 0.0137
Brugia malayi Serotonin receptor 0.0022 0.003 0.0042
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0029 0.0052 0.021
Echinococcus multilocularis histone deacetylase 8 0.0022 0.0031 0.0049
Brugia malayi nuclear receptor RXR 0.0012 0.0004 0.0005
Trichomonas vaginalis sugar transporter, putative 0.0018 0.002 0.0131
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0161
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0018 0.0021 0.0243
Leishmania major heat shock protein 83-1 0.0046 0.0099 0.0343
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0029 0.0203
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0022 0.003 0.0211
Schistosoma mansoni transcription factor LCR-F1 0.0122 0.0318 0.2048
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.0261 0.1052
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0014 0.0009 0.0006
Trichomonas vaginalis guanylate cyclase, putative 0.0022 0.003 0.0211
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.003 0.0122
Leishmania major trypanothione reductase 0.0041 0.0087 0.0299
Loa Loa (eye worm) glutathione reductase 0.0041 0.0087 0.0708
Plasmodium falciparum DNA gyrase subunit A 0.0047 0.0102 0.0351
Entamoeba histolytica DNA topoisomerase III, putative 0.0018 0.0019 0.0051
Loa Loa (eye worm) cytochrome P450 family protein 0.0051 0.0115 0.0942
Echinococcus multilocularis synaptic vesicle 2 protein 0.0018 0.002 0.0031
Loa Loa (eye worm) hypothetical protein 0.0024 0.0036 0.0292
Trichomonas vaginalis sugar transporter, putative 0.0018 0.002 0.0131
Trypanosoma brucei cytosine-specific DNA methylase, putative 0.0014 0.0008 0.0006
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.002 0.0026 0.0159
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0019 0.0125
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0023 0.0035 0.0109
Brugia malayi Cyclic-nucleotide gated cation channel 0.0012 0.0003 0.0004
Echinococcus granulosus peptide allatostatin:somatostatin 0.0022 0.003 0.0122
Toxoplasma gondii sugar transporter ST1 0.0018 0.002 0.0045
Trichomonas vaginalis sugar transporter, putative 0.0018 0.002 0.0131
Leishmania major heat shock protein 83-1 0.0046 0.0099 0.0343
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0018 0.0019 0.0044
Onchocerca volvulus Histone deacetylase 10 homolog 0.0022 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Trichomonas vaginalis DNA polymerase eta, putative 0.0038 0.0078 0.0591
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0018 0.0021 0.0137
Trypanosoma brucei glucose transporter, putative 0.0035 0.0067 0.0227
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Leishmania major glucose transporter, lmgt1 0.0035 0.0067 0.0227
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0019 0.0021 0.0254
Toxoplasma gondii Erv1 / Alr family protein 0.0027 0.0047 0.0145
Mycobacterium ulcerans DNA gyrase subunit A 0.0047 0.0102 0.0844
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Echinococcus multilocularis heat shock protein 90 0.0027 0.0046 0.0073
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0024 0.0036 0.0057
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0029 0.0052 0.021
Echinococcus granulosus caspase 2 0.0139 0.0366 0.1479
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Giardia lamblia GTOR 0.0039 0.0081 0.0266
Echinococcus granulosus DNA methyltransferase 2, putative 0.0014 0.0008 0.0031
Schistosoma mansoni biogenic amine receptor 0.0022 0.003 0.0194
Giardia lamblia Sgs1 DNA helicase, putative 0.0073 0.0177 0.0621
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0161
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.002 0.0026 0.0345
Schistosoma mansoni DNA helicase recq1 0.0073 0.0177 0.1137
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0114 0.0294 0.0405
Echinococcus granulosus calcium dependent protein kinase 0.0028 0.0049 0.0196
Echinococcus granulosus neuropeptides capa receptor 0.0022 0.003 0.0122
Echinococcus multilocularis disco interacting protein 2 0.0028 0.0047 0.0075
Onchocerca volvulus 0.0046 0.0101 0.0101
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0024 0.0036 0.0049
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0029 0.0052 0.0082
Echinococcus multilocularis neuropeptide receptor A26 0.0875 0.2475 0.392
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.002 0.0026 0.0159
Brugia malayi Cell death protein 3 precursor 0.0139 0.0366 0.0504
Schistosoma mansoni tar DNA-binding protein 0.0051 0.0114 0.0731
Echinococcus granulosus lipoxygenase domain containing protein 0.0015 0.001 0.0042
Onchocerca volvulus 0.0022 0.003 0.003
Echinococcus multilocularis Polycystic kidney disease protein 0.0015 0.001 0.0017
Schistosoma mansoni sugar transporter 0.0018 0.002 0.0127
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0012 0.0003 0.0005
Wolbachia endosymbiont of Brugia malayi DNA gyrase subunit A 0.0047 0.0102 0.3217
Leishmania major modification methylase-like protein 0.0014 0.0008 0.0006
Trichomonas vaginalis histone deacetylase, putative 0.0077 0.0188 0.1459
Trypanosoma brucei heat shock protein, putative 0.0046 0.0099 0.0343
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.003 0.0211
Toxoplasma gondii NADPH-glutathione reductase 0.0014 0.0009 0.0006
Onchocerca volvulus 0.0018 0.002 0.002
Echinococcus granulosus caspase 0.019 0.0513 0.2073
Echinococcus granulosus neuropeptide FF receptor 2 0.0022 0.003 0.0122
Onchocerca volvulus 0.0018 0.002 0.002
Echinococcus multilocularis tumor protein p63 0.0296 0.0816 0.1293
Onchocerca volvulus 0.0022 0.003 0.003
Schistosoma mansoni hypothetical protein 0.002 0.0026 0.017
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0027 0.0047 0.0145
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0023 0.0124
Giardia lamblia DNA repair protein RAD52 0.0876 0.2479 0.9152
Trypanosoma cruzi DNA topoisomerase II, putative 0.0224 0.061 0.2236
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0094 0.0239 0.4027
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0087 0.0217 0.3652
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0022 0.003 0.0194
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.002 0.0131
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0029 0.0052 0.0082
Trichomonas vaginalis sugar transporter, putative 0.0018 0.002 0.0131
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.003 0.0053 0.0174
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0051 0.0113 0.0179
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.003 0.0122
Plasmodium falciparum heat shock protein 90 0.0046 0.0099 0.0337
Entamoeba histolytica protein kinase, putative 0.003 0.0054 0.019
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0024 0.0036 0.023
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.003 0.0054 0.0085
Toxoplasma gondii heat shock protein 75, putative 0.0014 0.0008 0.0002
Onchocerca volvulus Protein cycle homolog 0.0025 0.004 0.004
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0022 0.0032 0.0051
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0242 0.0661 0.0911
Brugia malayi Calcitonin receptor-like protein seb-1 0.0126 0.0328 0.0452
Brugia malayi Isocitrate dehydrogenase 0.0029 0.0052 0.0072
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0184
Toxoplasma gondii transporter, major facilitator family protein 0.0018 0.002 0.0045
Brugia malayi hypothetical protein 0.0012 0.0004 0.0005
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0012 0.0003 0.0021
Trypanosoma cruzi histone deacetylase, putative 0.0022 0.0031 0.0093
Schistosoma mansoni microtubule-associated protein tau 0.0553 0.1554 1
Trichomonas vaginalis sugar transporter, putative 0.0018 0.002 0.0131
Trypanosoma cruzi cytochrome P450, putative 0.0028 0.0048 0.0157
Onchocerca volvulus 0.0022 0.003 0.003
Schistosoma mansoni hypothetical protein 0.0086 0.0214 0.1379
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0242 0.0661 0.0911
Brugia malayi Doublecortin family protein 0.0015 0.001 0.0014
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0029 0.0052 0.0171
Onchocerca volvulus 0.0022 0.003 0.003
Loa Loa (eye worm) thioredoxin reductase 0.0041 0.0087 0.0708
Schistosoma mansoni pyruvate dehydrogenase 0.0018 0.0021 0.0132
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0056
Trypanosoma brucei unspecified product 0.0032 0.006 0.0202
Plasmodium vivax acyl-CoA synthetase, putative 0.0014 0.0009 0.0004
Mycobacterium tuberculosis Probable reductase 0.0094 0.0239 0.4027
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0215 0.0583 0.5181
Brugia malayi histone deacetylase 11 0.0022 0.0031 0.0043
Echinococcus multilocularis muscleblind protein 1 0.0277 0.0762 0.1207
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0072 0.0174 0.1347
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0039 0.0081 0.0128
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Leishmania major heat shock protein 83-1 0.0046 0.0099 0.0343
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0024 0.0037 0.0059
Trichomonas vaginalis Ferredoxin 7 0.0015 0.001 0.0054
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0029 0.0052 0.0165
Echinococcus granulosus biogenic amine 5HT receptor 0.0022 0.003 0.0122
Trypanosoma brucei glucose transporter, putative 0.0035 0.0067 0.0227
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.002 0.0026 0.0345
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0273 0.0752 0.3012
Wolbachia endosymbiont of Brugia malayi topoisomerase IA, TopA 0.0018 0.0019 0.0354
Plasmodium falciparum acyl-CoA synthetase 0.0014 0.0009 0.0004
Loa Loa (eye worm) major facilitator superfamily transporter 0.0018 0.002 0.0161
Entamoeba histolytica hypothetical protein 0.0122 0.0318 0.126
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0096 0.0334
Toxoplasma gondii isocitrate dehydrogenase 0.0029 0.0052 0.0165
Plasmodium falciparum glutathione reductase 0.0041 0.0087 0.0293
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0072 0.0174 0.1121
Mycobacterium ulcerans acyl-CoA synthetase 0.0019 0.0023 0.0124
Giardia lamblia Lysyl-tRNA synthetase 0.0022 0.0031 0.0079
Mycobacterium leprae Conserved hypothetical protein 0.002 0.0026 0.021
Loa Loa (eye worm) transcription factor SMAD2 0.0205 0.0556 0.454
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0031
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0012 0.0003 0.0026
Schistosoma mansoni retinoic acid receptor RXR 0.0024 0.0036 0.023
Trypanosoma brucei heat shock protein 84, putative 0.0014 0.0008 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0024 0.0036 0.0049
Brugia malayi Steroid receptor seven-up type 2 0.0024 0.0036 0.0049
Trypanosoma brucei heat shock protein, putative 0.0046 0.0099 0.0343
Giardia lamblia Telomerase catalytic subunit 0.0956 0.2708 1
Leishmania major histone deacetylase, putative 0.0077 0.0188 0.0676
Brugia malayi glutathione reductase 0.0041 0.0087 0.012
Schistosoma mansoni tar DNA-binding protein 0.0051 0.0114 0.0731
Schistosoma mansoni protein kinase 0.003 0.0054 0.0347
Schistosoma mansoni neuropeptide F-like receptor 0.0022 0.003 0.0194
Loa Loa (eye worm) hypothetical protein 0.0158 0.0422 0.3444
Schistosoma mansoni survival motor neuron protein 0.0089 0.0224 0.1444
Entamoeba histolytica hypothetical protein 0.0022 0.0031 0.0096
Schistosoma mansoni hypothetical protein 0.0102 0.0261 0.1677
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.002 0.0026 0.0159
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0051 0.0113 0.0727
Treponema pallidum hypothetical protein 0.0061 0.0143 0.1799
Trichomonas vaginalis glucose transporter, putative 0.0018 0.002 0.0131
Schistosoma mansoni biogenic amine receptor 0.0022 0.003 0.0194
Echinococcus granulosus heat shock protein 90 0.0046 0.0099 0.0399
Echinococcus multilocularis g protein coupled receptor 0.0022 0.003 0.0048
Brugia malayi RNA recognition motif domain containing protein 0.0051 0.0114 0.0156
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0022 0.003 0.0194
Toxoplasma gondii histone deacetylase HDAC1 0.0022 0.0031 0.0086
Brugia malayi MH1 domain containing protein 0.0014 0.0008 0.0011
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0047 0.0103 0.036
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0022 0.003 0.0048
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Schistosoma mansoni serine/threonine protein kinase 0.003 0.0054 0.0347
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0025 0.0069
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0018 0.0019 0.0125
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0024 0.0036 0.0057
Trypanosoma cruzi metacaspase, putative 0.0072 0.0174 0.0623
Echinococcus multilocularis RUN 0.0015 0.001 0.0017
Toxoplasma gondii protein kinase, putative 0.0276 0.076 0.2785
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0024 0.0036 0.023
Echinococcus granulosus DNA topoisomerase 3 alpha 0.0018 0.0019 0.0079
Brugia malayi Bloom's syndrome protein homolog 0.0098 0.0248 0.0342
Echinococcus multilocularis thyroid hormone receptor alpha 0.0024 0.0036 0.0057
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0014 0.0009 0.0012
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0018 0.0021 0.0243
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0154 0.0409 0.6971
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0018 0.0021 0.0106
Plasmodium vivax CDK-related protein kinase 6, putative 0.0415 0.1157 0.4257
Loa Loa (eye worm) RNA binding protein 0.0051 0.0114 0.0927
Schistosoma mansoni neuropeptide receptor 0.0022 0.003 0.0194
Trichomonas vaginalis Ferredoxin 3 0.0015 0.001 0.0054
Trypanosoma cruzi histone deacetylase, putative 0.0022 0.0031 0.0093
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0024 0.0036 0.0292
Trypanosoma brucei DNA polymerase IV, putative 0.0032 0.006 0.0202
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0035 0.0255
Schistosoma mansoni coup transcription factor 0.0024 0.0036 0.023
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0102 0.0261 0.0413
Schistosoma mansoni caspase-7 (C14 family) 0.0139 0.0366 0.2357
Echinococcus multilocularis dro:myosuppressin receptor 0.0022 0.003 0.0048
Echinococcus granulosus ferredoxin 0.0015 0.001 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0044 0.032
Leishmania major DNA polymerase eta, putative 0.0014 0.0007 0.0004
Toxoplasma gondii lysine-tRNA ligase 0.0022 0.0031 0.0085
Brugia malayi hypothetical protein 0.0015 0.001 0.0014
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0022 0.003 0.0211
Brugia malayi Adrenodoxin-like protein, mitochondrial precursor, putative 0.0015 0.001 0.0014
Brugia malayi intermediate filament protein 0.005 0.0111 0.0153
Loa Loa (eye worm) hypothetical protein 0.0024 0.0036 0.0292
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.003 0.0054 0.0218
Giardia lamblia Fructose-bisphosphate aldolase 0.0273 0.0752 0.2751
Loa Loa (eye worm) hypothetical protein 0.0103 0.0264 0.2154
Plasmodium falciparum calcium-dependent protein kinase 3 0.003 0.0054 0.0171
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0233 0.0635 0.233
Brugia malayi Major Facilitator Superfamily protein 0.0018 0.002 0.0027
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0019 0.0021 0.0254
Brugia malayi photoreceptor-specific nuclear receptor 0.0024 0.0036 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0174 0.1347
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0174 0.1347
Mycobacterium ulcerans oxidoreductase 0.0015 0.001 0.0011
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0034 0.0066 0.0216
Trypanosoma brucei glucose transporter, putative 0.0035 0.0067 0.0227
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0023 0.0035 0.0109
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0014 0.0009 0.0013
Leishmania major hypothetical protein, conserved 0.0027 0.0047 0.0152
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0233 0.0635 0.233
Loa Loa (eye worm) hypothetical protein 0.0024 0.0036 0.0292
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0047 0.0103 0.036
Loa Loa (eye worm) hypothetical protein 0.0022 0.0031 0.0252
Echinococcus granulosus biogenic amine 5HT receptor 0.0022 0.003 0.0122
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0022 0.003 0.003
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0113 0.0292 0.2385
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0014 0.0008 0.0013
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0018 0.0019 0.0128
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0029 0.0052 0.0082
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0072 0.0174 0.1347
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0022 0.003 0.0211
Echinococcus granulosus FTZ F1 alpha 0.0024 0.0036 0.0145
Onchocerca volvulus 0.0018 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Onchocerca volvulus 0.0018 0.002 0.002
Echinococcus multilocularis lysyl tRNA synthetase 0.0022 0.0031 0.0048
Trypanosoma cruzi DNA topoisomerase IA, putative 0.0018 0.0019 0.005
Echinococcus multilocularis histone deacetylase 6 0.0022 0.0031 0.0049
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.003 0.0053 0.0174
Trichomonas vaginalis DNA helicase recq1, putative 0.0098 0.0248 0.1929
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.002 0.0026 0.0159
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0029 0.0203
Mycobacterium ulcerans flavodoxin oxidoreductase 0.0015 0.001 0.0011
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0106 0.0429
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0022 0.0031 0.0197
Entamoeba histolytica protein kinase, putative 0.003 0.0054 0.019
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0024 0.0036 0.0049
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.003 0.0054 0.0171
Loa Loa (eye worm) hypothetical protein 0.0041 0.0085 0.0695
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0039 0.0081 0.0299
Leishmania major telomerase reverse transcriptase, putative 0.0956 0.2708 1
Trichomonas vaginalis adenylate cyclase, putative 0.0022 0.003 0.0211
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0014 0.0009 0.0006
Giardia lamblia DNA topoisomerase III 0.0018 0.0019 0.0038
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0073 0.0177 0.0626
Mycobacterium ulcerans glutaminase 0.0401 0.1118 1
Echinococcus multilocularis transfer RNA-Lys 0.0032 0.0058 0.0093
Plasmodium falciparum mitogen-activated protein kinase 2 0.0158 0.0421 0.153
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.002 0.0131
Plasmodium falciparum ataxin-2 like protein, putative 0.0103 0.0264 0.0949
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0455 0.1273 1
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0018 0.0021 0.0033
Echinococcus multilocularis flap endonuclease 1 0.0047 0.0103 0.0164
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0022 0.003 0.0194
Trichomonas vaginalis sugar transporter, putative 0.0018 0.002 0.0131
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.002 0.0026 0.0159
Trypanosoma brucei histone deacetylase, putative 0.0022 0.0031 0.0093
Brugia malayi hypothetical protein 0.0012 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0438 0.1225 1
Loa Loa (eye worm) TYRA-2 protein 0.0022 0.003 0.0246
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0078 0.0267
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.003 0.0194
Schistosoma mansoni amine GPCR 0.0022 0.003 0.0194
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0029 0.0203
Chlamydia trachomatis DNA topoisomerase I 0.0018 0.0019 0.0338
Echinococcus granulosus muscleblind protein 0.0277 0.0762 0.3078
Schistosoma mansoni single-minded 0.0053 0.012 0.0775
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0014 0.0009 0.0014
Trichomonas vaginalis histone deacetylase, putative 0.0077 0.0188 0.1459
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0058 0.0134 0.1098
Entamoeba histolytica hypothetical protein 0.0122 0.0318 0.126
Plasmodium vivax DNA gyrase subunit A, putative 0.0047 0.0102 0.0351
Onchocerca volvulus 0.0022 0.003 0.003
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.003 0.0122
Schistosoma mansoni biogenic amine (5HT) receptor 0.0022 0.003 0.0194
Trichomonas vaginalis sugar transporter, putative 0.0018 0.002 0.0131
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0012 0.0003 0.0013
Leishmania major histone deacetylase, putative 0.0022 0.0031 0.0093
Entamoeba histolytica hypothetical protein 0.0122 0.0318 0.126
Mycobacterium ulcerans oxidoreductase 0.0015 0.001 0.0011
Loa Loa (eye worm) G-protein coupled receptor 0.0022 0.003 0.0246
Echinococcus granulosus TGF beta signal transducer SmadC 0.0014 0.0008 0.0033
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.003 0.0194
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0161
Loa Loa (eye worm) hypothetical protein 0.0073 0.0177 0.1443
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Schistosoma mansoni sugar transporter 0.0018 0.002 0.0127
Trypanosoma cruzi heat shock protein 90, putative 0.0032 0.0058 0.0195
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0052 0.0384
Toxoplasma gondii heat shock protein HSP90 0.0046 0.0099 0.0337
Toxoplasma gondii facilitative glucose transporter GT1 0.0102 0.0261 0.0937
Mycobacterium leprae Probable two-component sensor kinase 0.0018 0.0021 0.0033
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0047 0.0103 0.036
Schistosoma mansoni endoplasmin 0.0046 0.0099 0.0635
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0106 0.0168
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.004 0.0082 0.013
Plasmodium vivax heat shock protein, putative 0.0014 0.0008 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0006 0.0022
Echinococcus granulosus Adrenodoxin mitochondrial 0.0015 0.001 0.004
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0029 0.0052 0.0183
Trichomonas vaginalis heat shock protein, putative 0.0014 0.0008 0.004
Echinococcus multilocularis G-protein coupled receptor, putative 0.0022 0.003 0.0048
Toxoplasma gondii hypothetical protein 0.0059 0.0137 0.0481
Mycobacterium ulcerans hypothetical protein 0.0167 0.0448 0.3961
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0029 0.0052 0.0386
Echinococcus multilocularis endoplasmin 0.0027 0.0046 0.0073
Brugia malayi G protein-coupled receptor 0.0022 0.003 0.0042
Brugia malayi G-protein coupled receptor 0.0022 0.003 0.0042
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Plasmodium falciparum calcium-dependent protein kinase 5 0.003 0.0054 0.0171
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.003 0.0194
Trypanosoma cruzi heat shock protein 90, putative 0.0027 0.0046 0.0149
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0072 0.0174 0.0617
Trichomonas vaginalis heat shock protein, putative 0.0032 0.0061 0.0453
Echinococcus granulosus synaptic vesicle 2 protein 0.0018 0.002 0.008
Schistosoma mansoni hypothetical protein 0.004 0.0082 0.0528
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0024 0.0036 0.0049
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0072 0.0174 0.024
Leishmania major heat shock protein 83-1 0.0046 0.0099 0.0343
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0073 0.0177 0.0626
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.001 0.0015
Leishmania major heat shock protein, putative 0.0014 0.0008 0.0009
Loa Loa (eye worm) hypothetical protein 0.0024 0.0036 0.0292
Trypanosoma brucei glucose transporter, putative 0.0035 0.0067 0.0227
Schistosoma mansoni cytochrome P450 0.002 0.0026 0.017
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0024 0.0036 0.0292
Schistosoma mansoni opsin-like receptor 0.0022 0.003 0.0194
Echinococcus multilocularis neuropeptide Y receptor 0.0022 0.003 0.0048
Brugia malayi kinase, mitochondrial precursor 0.0018 0.0021 0.0028
Trichomonas vaginalis sugar transporter, putative 0.0018 0.002 0.0131
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0018 0.0021 0.0243
Trichomonas vaginalis sensor histidine kinase, putative 0.0018 0.0021 0.0137
Onchocerca volvulus 0.0018 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0043 0.0092 0.0753
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.0174 0.1347
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.003 0.0048
Brugia malayi MH2 domain containing protein 0.0014 0.0008 0.0011
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0018 0.0021 0.0137
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0052 0.0384
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0036 0.023
Echinococcus granulosus histone lysine methyltransferase setb 0.0051 0.0113 0.0457
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.003 0.0122
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0025 0.0069
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Trypanosoma brucei telomerase reverse transcriptase 0.0956 0.2708 1
Echinococcus granulosus solute carrier family 22 0.0018 0.002 0.008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0064 0.0482
Schistosoma mansoni aryl hydrocarbon receptor 0.0054 0.0122 0.0788
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0052 0.0384
Onchocerca volvulus 0.0018 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0029 0.0051 0.0419
Echinococcus multilocularis histone deacetylase 7 0.0022 0.0031 0.0049
Trichomonas vaginalis glucose transporter, putative 0.0035 0.0067 0.0505
Schistosoma mansoni amine GPCR 0.0022 0.003 0.0194
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0022 0.003 0.0048
Mycobacterium tuberculosis Probable two component sensor kinase 0.0018 0.0021 0.0243
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0031
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0022 0.003 0.0048
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0006 0.0022
Echinococcus multilocularis solute carrier family 22 0.0018 0.002 0.0031
Schistosoma mansoni lipoxygenase 0.0088 0.0222 0.1426
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0058 0.043
Leishmania major myo-inositol/proton symporter (MIT) 0.0018 0.002 0.0051
Loa Loa (eye worm) phosphatidylinositol 3 0.0039 0.0081 0.066
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.002 0.0026 0.0345
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.002 0.0026 0.0159
Onchocerca volvulus 0.0022 0.003 0.003
Loa Loa (eye worm) histone deacetylase 1 0.0077 0.0188 0.1538
Onchocerca volvulus 0.0018 0.0019 0.0019
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0024 0.0036 0.0057
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.002 0.0026 0.0345
Trichomonas vaginalis guanylate cyclase, putative 0.0022 0.003 0.0211
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0046 0.0101 0.016
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.003 0.0122
Treponema pallidum DNA gyrase, subunit A (gyrA) 0.0047 0.0102 0.1255
Schistosoma mansoni blooms syndrome DNA helicase 0.0037 0.0074 0.0479
Loa Loa (eye worm) doublecortin family protein 0.0015 0.001 0.0085
Onchocerca volvulus Protein ultraspiracle homolog 0.0024 0.0036 0.0036
Echinococcus granulosus histone deacetylase 7 0.0022 0.0031 0.0125
Brugia malayi TAR-binding protein 0.0051 0.0114 0.0156
Plasmodium falciparum calcium-dependent protein kinase 1 0.003 0.0054 0.0171
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.003 0.0194
Toxoplasma gondii histone deacetylase HDAC5 0.0022 0.0031 0.0086
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0093 0.0233 0.0836
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.004 0.0082 0.2333
Brugia malayi Tachykinin-like peptides receptor 99D 0.0022 0.003 0.0042
Schistosoma mansoni lysyl-tRNA synthetase 0.0022 0.0031 0.0197
Echinococcus multilocularis g-protein coupled receptor 0.0022 0.003 0.0048
Loa Loa (eye worm) endoplasmin 0.0046 0.0099 0.0805
Toxoplasma gondii DNA topoisomerase family protein 0.0018 0.0019 0.0044
Leishmania major heat shock protein 83-1 0.0046 0.0099 0.0343
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0154 0.0409 0.3606
Mycobacterium ulcerans heat shock protein 90 0.0027 0.0046 0.0337
Toxoplasma gondii ferodoxin FD 0.0015 0.001 0.0009
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.019 0.0513 0.2073
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0029 0.0052 0.0171
Trypanosoma brucei glucose transporter, putative 0.0035 0.0067 0.0227
Leishmania major ferredoxin 2fe-2s-like protein 0.0015 0.001 0.0015
Brugia malayi AMP-binding enzyme family protein 0.0019 0.0023 0.0031
Trichomonas vaginalis set domain proteins, putative 0.0398 0.1108 0.8703
Schistosoma mansoni glucose transport protein 0.0102 0.0261 0.1677
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0027 0.0046 0.0186
Schistosoma mansoni adrenodoxin 0.0015 0.001 0.0064
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0022 0.0031 0.0336
Entamoeba histolytica DNA topoisomerase III, putative 0.0018 0.0019 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0041 0.03
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0058 0.043
Leishmania major hypothetical protein, conserved 0.0018 0.0021 0.0054
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.015 0.0399 0.1456
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0012 0.0003 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0078 0.0267
Echinococcus multilocularis microtubule associated protein 2 0.0553 0.1554 0.2461
Brugia malayi Inositol-1 0.003 0.0053 0.0073
Onchocerca volvulus 0.0027 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0019 0.0021 0.0057
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0014 0.0008 0.0013
Giardia lamblia [2Fe-2S] ferredoxin 0.0015 0.001 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0024 0.0036 0.0049
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0022 0.003 0.0089
Echinococcus granulosus g protein coupled receptor 0.0022 0.003 0.0122
Schistosoma mansoni hypothetical protein 0.0046 0.0101 0.0648
Schistosoma mansoni smad 0.0014 0.0008 0.0052
Loa Loa (eye worm) hypothetical protein 0.0066 0.0158 0.1288
Leishmania major hypothetical protein, conserved 0.0018 0.002 0.0051
Loa Loa (eye worm) latrophilin receptor protein 2 0.004 0.0082 0.0669
Trypanosoma brucei histone deacetylase 1 0.0077 0.0188 0.0676
Echinococcus multilocularis neuropeptides capa receptor 0.0022 0.003 0.0048
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0106 0.0168
Chlamydia trachomatis ferredoxin 0.0015 0.001 0.004
Plasmodium falciparum calcium-dependent protein kinase 4 0.003 0.0054 0.0171
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0105 0.0269 0.7533
Trypanosoma cruzi adrenodoxin precursor, putative 0.0015 0.001 0.0015
Schistosoma mansoni neuropeptide receptor 0.0022 0.003 0.0194
Echinococcus granulosus single minded 2 0.0037 0.0075 0.0302
Loa Loa (eye worm) CXXC zinc finger family protein 0.0046 0.0101 0.0825
Trypanosoma brucei metacaspase 0.0072 0.0174 0.0623
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0012 0.0003 0.0013
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2214 0.6314 1
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0066 0.0158 0.0611
Echinococcus granulosus fmrfamide receptor 0.0022 0.003 0.0122
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0024 0.0036 0.023
Trypanosoma brucei developmentally regulated phosphoprotein 0.0018 0.0021 0.0054
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0013 0.0006 0.0024
Onchocerca volvulus 0.0032 0.0061 0.0061
Loa Loa (eye worm) sugar transporter 0.0018 0.002 0.0161
Schistosoma mansoni heat shock protein 0.0046 0.0099 0.0635
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0035 0.0255
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0018 0.002 0.0099
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0161
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Schistosoma mansoni hypothetical protein 0.0122 0.0318 0.2048
Echinococcus multilocularis rho GTPase activating protein 20 0.0018 0.0019 0.0031
Brugia malayi Cam kinase protein 1 0.003 0.0054 0.0074
Brugia malayi DNA topoisomerase III 0.0018 0.0019 0.0027
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.003 0.0054 0.0218
Brugia malayi ImpB/MucB/SamB family protein 0.0014 0.0007 0.0009
Schistosoma mansoni sugar transporter 0.0018 0.002 0.0127
Loa Loa (eye worm) 2Fe-2S iron-sulfur cluster binding domain-containing protein 0.0015 0.001 0.0082
Loa Loa (eye worm) histone deacetylase 0.0022 0.0031 0.0252
Schistosoma mansoni histone deacetylase 0.0077 0.0188 0.1213
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0022 0.003 0.0246
Trichomonas vaginalis sugar transporter, putative 0.0018 0.002 0.0131
Schistosoma mansoni endoplasmin 0.0046 0.0099 0.0635
Loa Loa (eye worm) DNA topoisomerase III 0.0018 0.0019 0.0159
Echinococcus multilocularis dna polymerase eta 0.0014 0.0007 0.0011
Echinococcus granulosus somatostatin receptor 0.0022 0.003 0.0122
Treponema pallidum hypothetical protein 0.0074 0.018 0.2303
Onchocerca volvulus 0.0018 0.002 0.002
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0039 0.0081 0.0327
Trypanosoma cruzi histone deacetylase, putative 0.0022 0.0031 0.0093
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0062 0.0145 0.1187
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.003 0.0194
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0022 0.003 0.0122
Trichomonas vaginalis sugar transporter, putative 0.0018 0.002 0.0131
Echinococcus multilocularis isocitrate dehydrogenase 0.0029 0.0052 0.0082
Trypanosoma brucei PAB1-binding protein , putative 0.0103 0.0264 0.0955
Loa Loa (eye worm) hypothetical protein 0.0029 0.0052 0.0425
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Brugia malayi nuclear hormone receptor 0.0024 0.0036 0.0049
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0455 0.1273 1
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0073 0.0177 0.028
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0035 0.0249
Loa Loa (eye worm) DNA topoisomerase III beta-1 0.0018 0.0019 0.0159
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0022 0.003 0.0089
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0022 0.003 0.0211
Schistosoma mansoni ets-related 0.0176 0.0473 0.3046
Brugia malayi Hsp90 protein 0.0014 0.0008 0.0011
Loa Loa (eye worm) heat shock protein 75 0.0014 0.0008 0.0067
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0024 0.0036 0.0049
Brugia malayi Fli-1 protein 0.0176 0.0473 0.0652
Brugia malayi larval opioid receptor 0.0022 0.003 0.0042
Schistosoma mansoni DNA helicase recq5 0.0073 0.0177 0.1137
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0047 0.0103 0.0354
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0094 0.0239 0.4027
Toxoplasma gondii hypothetical protein 0.0051 0.0115 0.0398
Giardia lamblia Histone deacetylase 0.0077 0.0188 0.0664
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0078 0.0191 0.0687
Schistosoma mansoni DNA polymerase eta 0.0014 0.0007 0.0044
Leishmania major DNA topoisomerase 1A 0.0018 0.0019 0.005
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0018 0.0021 0.0153
Echinococcus granulosus endoplasmin 0.0027 0.0046 0.0186
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.003 0.0194
Plasmodium vivax histone deacetylase 2, putative 0.0022 0.0031 0.0086
Leishmania major glucose transporter, lmgt3 0.0035 0.0067 0.0227
Schistosoma mansoni lamin 0.005 0.0111 0.0717
Loa Loa (eye worm) hypothetical protein 0.003 0.0054 0.044
Trypanosoma cruzi histone deacetylase 1, putative 0.0077 0.0188 0.0676
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.003 0.0054 0.0171
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0022 0.003 0.0042
Echinococcus multilocularis serotonin receptor 0.0022 0.003 0.0048
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0024 0.0036 0.0145
Brugia malayi Muscleblind-like protein 0.0277 0.0762 0.105
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0161
Trypanosoma brucei heat shock protein 90, putative 0.0046 0.0099 0.0343
Schistosoma mansoni tar DNA-binding protein 0.0051 0.0114 0.0731
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0122 0.0318 0.1286
Loa Loa (eye worm) cytochrome P450 0.002 0.0026 0.0216
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0029 0.0052 0.0335
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0014 0.0007 0.0011
Schistosoma mansoni voltage-gated potassium channel 0.0068 0.0162 0.1041
Echinococcus multilocularis mothers against decapentaplegic 5 0.0014 0.0008 0.0013
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0956 0.2708 1
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0034 0.0066 0.0223
Leishmania major glucose transporter/membrane transporter D2, putative 0.0035 0.0067 0.0227
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0072 0.0174 0.1347
Loa Loa (eye worm) hypothetical protein 0.0051 0.0113 0.0923
Leishmania major glucose transporter, lmgt2 0.0035 0.0067 0.0227
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0034 0.0066 0.0223
Brugia malayi hypothetical protein 0.0025 0.0038 0.0053
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0158 0.0421 0.153
Trypanosoma cruzi metacaspase, putative 0.0072 0.0174 0.0623
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0273 0.0752 0.5893
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0051 0.0113 0.0727
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0126 0.0328 0.2679
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0006 0.0022
Echinococcus multilocularis g protein coupled receptor 0.0022 0.003 0.0048
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0022 0.003 0.0048
Onchocerca volvulus Cell death protein 3 homolog 0.0139 0.0366 0.0366
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0014 0.0009 0.0012
Toxoplasma gondii Erv1 / Alr family protein 0.0027 0.0047 0.0145
Plasmodium falciparum heat shock protein 90, putative 0.0014 0.0008 0.0002
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0956 0.2708 1
Loa Loa (eye worm) hypothetical protein 0.0086 0.0214 0.1749
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0078 0.0267
Onchocerca volvulus 0.0024 0.0036 0.0036
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0029 0.0052 0.0986
Echinococcus granulosus thioredoxin glutathione reductase 0.0041 0.0087 0.0351
Loa Loa (eye worm) hypothetical protein 0.0029 0.0052 0.0425
Leishmania major protein kinase, putative 0.0023 0.0035 0.0109
Trichomonas vaginalis Ferredoxin 6 0.0015 0.001 0.0054
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0072 0.0174 0.0617
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0022 0.003 0.0246
Treponema pallidum DNA topoisomerase I (topA) 0.0018 0.0019 0.0138
Schistosoma mansoni voltage-gated potassium channel 0.0068 0.0162 0.1041
Schistosoma mansoni hypothetical protein 0.0015 0.001 0.0067
Trypanosoma cruzi hexose transporter, putative 0.0035 0.0067 0.0227
Echinococcus multilocularis fmrfamide receptor 0.0022 0.003 0.0048
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.003 0.0053 0.0398
Trypanosoma cruzi PAB1-binding protein , putative 0.0103 0.0264 0.0955
Loa Loa (eye worm) hypothetical protein 0.0106 0.0273 0.2231
Plasmodium vivax hexose transporter 0.0102 0.0261 0.0937
Brugia malayi hypothetical protein 0.0067 0.0159 0.0219
Echinococcus granulosus G protein coupled receptor 139 0.0022 0.003 0.0122
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0031 0.0058 0.0192
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Entamoeba histolytica recQ family DNA helicase 0.0037 0.0074 0.0273
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0072 0.0174 0.1347
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.0018 0.0021 0.0392
Trichomonas vaginalis Ferredoxin 2 0.0015 0.001 0.0054
Brugia malayi G-protein coupled receptor 0.0022 0.003 0.0042
Plasmodium vivax DNA gyrase subunit B, putative 0.0115 0.0299 0.1078
Trichomonas vaginalis sugar transporter, putative 0.0018 0.002 0.0131
Echinococcus multilocularis fmrfamide receptor 0.0022 0.003 0.0048
Onchocerca volvulus 0.0022 0.003 0.003
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0027 0.0046 0.0806
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0022 0.003 0.0048
Schistosoma mansoni glucose transport protein 0.0102 0.0261 0.1677
Trichomonas vaginalis receptor histidine kinase, putative 0.0018 0.0021 0.0137
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.002 0.0026 0.0159
Loa Loa (eye worm) hypothetical protein 0.0072 0.0174 0.1422
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0078 0.0267
Trichomonas vaginalis histone deacetylase, putative 0.0077 0.0188 0.1459
Schistosoma mansoni inositol monophosphatase 0.003 0.0053 0.0341
Schistosoma mansoni inositol monophosphatase 0.003 0.0053 0.0341
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0029 0.0052 0.0335
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0022 0.003 0.0194
Echinococcus granulosus GPCR family 2 0.004 0.0082 0.0331
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0022 0.0032 0.0129
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.003 0.0194
Trichomonas vaginalis CAMK family protein kinase 0.003 0.0054 0.0399
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Brugia malayi AMP-binding enzyme family protein 0.0019 0.0023 0.0031
Echinococcus multilocularis dna polymerase kappa 0.0038 0.0078 0.0124
Onchocerca volvulus 0.0019 0.0023 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0078 0.0267
Brugia malayi RNA binding protein 0.0051 0.0114 0.0156
Plasmodium falciparum adrenodoxin-type ferredoxin, putative 0.0015 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0015 0.001 0.0085
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Onchocerca volvulus 0.0022 0.003 0.003
Trypanosoma cruzi hexose transporter, putative 0.0017 0.0016 0.0036
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.002 0.0026 0.0159
Loa Loa (eye worm) CYP4Cod1 0.0028 0.0048 0.0395
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0004 0.0025
Trypanosoma cruzi histone deacetylase 1, putative 0.0077 0.0188 0.0676
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0073 0.0177 0.1443
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Brugia malayi Ets-domain containing protein 0.0058 0.0134 0.0185
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0078 0.0267
Mycobacterium ulcerans flavodoxin reductase Hmp 0.0015 0.001 0.0011
Echinococcus granulosus lamin 0.005 0.0111 0.045
Brugia malayi hypothetical protein 0.0022 0.003 0.0042
Onchocerca volvulus 0.0018 0.002 0.002
Trichomonas vaginalis sugar transporter, putative 0.0035 0.0067 0.0505
Schistosoma mansoni polycystin 1-related 0.0015 0.001 0.0067
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Echinococcus granulosus 7tm_1 domain containing protein 0.0022 0.003 0.0122
Leishmania major heat shock protein 83-1 0.0046 0.0099 0.0343
Echinococcus granulosus voltage gated potassium channel 0.0018 0.0019 0.0079
Schistosoma mansoni histone deacetylase 4 5 0.0022 0.0031 0.0199
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0018 0.0021 0.0048
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0019 0.0023 0.0184
Echinococcus granulosus neuropeptide receptor 0.0022 0.003 0.0122
Trypanosoma cruzi sugar transporter, putative 0.0018 0.002 0.0051
Trypanosoma brucei heat shock protein, putative 0.0046 0.0099 0.0343
Plasmodium vivax hypothetical protein, conserved 0.0072 0.0174 0.0617
Schistosoma mansoni DNA (cytosine-5)-methyltransferase 0.0014 0.0008 0.0049
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.003 0.0048
Mycobacterium ulcerans oxygenase 0.0015 0.001 0.0011
Mycobacterium ulcerans hypothetical protein 0.0074 0.018 0.1546
Echinococcus multilocularis hyperpolarization activated cyclic 0.0012 0.0003 0.0005
Echinococcus granulosus heat shock protein 0.0046 0.0099 0.0399
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0013 0.0006 0.0038
Mycobacterium ulcerans acyl-CoA synthetase 0.0019 0.0023 0.0124
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0029 0.0203
Mycobacterium ulcerans two component regulator - sensor kinase 0.0018 0.0021 0.0106
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.002 0.0131
Echinococcus multilocularis DNA topoisomerase 3 beta 1 0.0018 0.0019 0.0031
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.003 0.0048
Echinococcus granulosus inositol monophosphatase 1 0.003 0.0053 0.0214
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.002 0.0026 0.0345
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0014 0.0009 0.0012
Loa Loa (eye worm) fli-1 protein 0.0176 0.0473 0.3863
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0031
Leishmania major metacaspase, putative 0.0072 0.0174 0.0623
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0024 0.0036 0.0297
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0047 0.0102 0.0835
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0018 0.0021 0.0106
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0058 0.0134 0.1028
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0051 0.0168
Onchocerca volvulus 0.0018 0.002 0.002
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0048 0.0395
Echinococcus granulosus GA binding protein alpha chain 0.0058 0.0134 0.0543
Onchocerca volvulus 0.0018 0.002 0.002
Mycobacterium tuberculosis Possible oxygenase 0.0015 0.001 0.006
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.0071
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Onchocerca volvulus 0.0018 0.002 0.002
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0014 0.0009 0.0046
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0018 0.0019 0.0079
Leishmania major 4-coumarate:coa ligase-like protein 0.0019 0.0023 0.0062
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0073 0.0177 0.0714
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.004 0.0082 0.0113
Trypanosoma cruzi DNA topoisomerase III, putative 0.0018 0.0019 0.005
Trypanosoma brucei THT1 - hexose transporter, putative 0.0035 0.0067 0.0227
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0019 0.0023 0.0093
Plasmodium vivax flap endonuclease 1, putative 0.0047 0.0103 0.0354
Echinococcus granulosus tachykinin peptides receptor 99D 0.0022 0.003 0.0122
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0318 0.0879 0.3232
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0215 0.0583 0.5181
Echinococcus multilocularis survival motor neuron protein 1 0.0438 0.1225 0.194
Chlamydia trachomatis Na(+)-translocating NADH-quinone reductase subunit F 0.0015 0.001 0.004
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0018 0.0021 0.0048
Trichomonas vaginalis sugar transporter, putative 0.0018 0.002 0.0131
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0022 0.003 0.0211
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0081 0.0612
Echinococcus granulosus serotonin receptor 0.0022 0.003 0.0122
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0004 0.0005
Schistosoma mansoni histone deacetylase 1 2 3 0.0022 0.0031 0.0199
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0018 0.0021 0.0106
Mycobacterium ulcerans putative regulatory protein 0.0032 0.0058 0.0448
Loa Loa (eye worm) hypothetical protein 0.0027 0.0045 0.0369
Brugia malayi Serotonin receptor 0.0022 0.003 0.0042
Trichomonas vaginalis myo-inositol transporter, putative 0.0018 0.002 0.0131
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0876 0.2479 1
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0024 0.0036 0.0036
Echinococcus multilocularis histone deacetylase 3 0.0077 0.0188 0.0298
Echinococcus granulosus hypothetical protein 0.0022 0.003 0.0122
Trypanosoma brucei glucose transporter 1E 0.0035 0.0067 0.0227
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0024 0.0036 0.0049
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0029 0.0052 0.0072
Plasmodium falciparum heat shock protein 90, putative 0.0014 0.0008 0.0002
Brugia malayi hypothetical protein 0.0438 0.1225 0.1687
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0072 0.0174 0.1347
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0022 0.003 0.0042
Leishmania major developmentally regulated phosphoprotein-like protein 0.0018 0.0021 0.0054
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0022 0.003 0.0048
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0014 0.0009 0.0012
Mycobacterium tuberculosis Probable dehydrogenase 0.0094 0.0239 0.4027
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.003 0.0054 0.0085
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0012 0.0003 0.002
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0051 0.0114 0.0927
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0018 0.0021 0.0243
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0126 0.0328 0.0452
Toxoplasma gondii thioredoxin reductase 0.0041 0.0087 0.0293
Schistosoma mansoni tar DNA-binding protein 0.0051 0.0114 0.0731
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0161
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0012 0.0024
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0161
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.004 0.0082 0.0331
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0054 0.0124 0.0438
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0078 0.0267
Trichomonas vaginalis sugar transporter, putative 0.0018 0.002 0.0131
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0014 0.0009 0.0037
Schistosoma mansoni lysyl-tRNA synthetase 0.0022 0.0031 0.0197
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0081 0.0612
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.002 0.0026 0.0076
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.003 0.0054 0.0074
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0273 0.0752 0.5893
Mycobacterium tuberculosis Probable oxidoreductase 0.0105 0.0269 0.4551
Echinococcus granulosus alpha 1A adrenergic receptor 0.0022 0.003 0.0122
Chlamydia trachomatis lysine--tRNA ligase 0.0022 0.0031 0.0691
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0072 0.0174 0.1347
Echinococcus granulosus DNA topoisomerase 3 beta 1 0.0018 0.0019 0.0079
Loa Loa (eye worm) hypothetical protein 0.0018 0.002 0.0161
Loa Loa (eye worm) hypothetical protein 0.0012 0.0003 0.0026
Giardia lamblia Prolyl-tRNA synthetase 0.0029 0.0052 0.0159
Plasmodium vivax ataxin-2 like protein, putative 0.0103 0.0264 0.0949
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0035 0.0255
Trypanosoma brucei trypanothione reductase 0.0041 0.0087 0.0299
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.003 0.0048
Leishmania major heat shock protein 83-1 0.0046 0.0099 0.0343
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0018 0.0021 0.0392
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0072 0.0174 0.1347
Brugia malayi Sugar transporter family protein 0.0018 0.002 0.0027
Trichomonas vaginalis myo inositol monophosphatase, putative 0.003 0.0053 0.0392
Trypanosoma cruzi DNA topoisomerase III, putative 0.0018 0.0019 0.005
Echinococcus granulosus hyperpolarization activated cyclic 0.0012 0.0003 0.0013
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0087 0.0217 0.188
Brugia malayi hypothetical protein 0.0022 0.003 0.0042
Echinococcus multilocularis solute carrier family 22 0.0018 0.002 0.0031
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0171 0.0459 0.0459
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0012 0.0003 0.0005
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.003 0.0054 0.0218
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0024 0.0036 0.023
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0012 0.0004 0.0031
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0034 0.0066 0.0223
Echinococcus granulosus histone deacetylase 0.0022 0.0031 0.0125
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0014 0.0009 0.0015
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0039 0.0081 0.0277
Brugia malayi Augmenter of liver regeneration 0.0027 0.0047 0.0065
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0009 0.0012
Echinococcus granulosus histone deacetylase 1 0.0077 0.0188 0.0761
Plasmodium vivax histone deacetylase, putative 0.0022 0.0031 0.0086
Trypanosoma brucei metacaspase MCA2 0.0072 0.0174 0.0623
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.005 0.0111 0.0909
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0018 0.0021 0.0106
Echinococcus granulosus disco interacting protein 2 0.0028 0.0047 0.0191
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0302 0.0833 0.7428
Schistosoma mansoni myosin xvIII 0.0022 0.003 0.0194
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0073 0.0177 0.0626
Trypanosoma cruzi heat shock protein 90, putative 0.0046 0.0099 0.0343
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.003 0.0053 0.0174
Trypanosoma brucei NADH-ubiquinone oxidoreductase complex I subunit, putative 0.0015 0.001 0.0015
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0018 0.0021 0.0106
Leishmania major DNA polymerase kappa, putative 0.002 0.0025 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0052 0.0384
Brugia malayi MH2 domain containing protein 0.0014 0.0008 0.0011
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0014 0.0009 0.0012
Onchocerca volvulus 0.005 0.0111 0.0111
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0029 0.0052 0.0789
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0102 0.0261 0.0413
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0027 0.0046 0.0687
Echinococcus granulosus Polycystic kidney disease protein 0.0015 0.001 0.0042
Plasmodium vivax histone deacetylase 1, putative 0.0077 0.0188 0.067
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.003 0.0122
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0012 0.0003 0.0026
Mycobacterium ulcerans DNA polymerase IV 0.0038 0.0078 0.0626
Trypanosoma cruzi hexose transporter, putative 0.0035 0.0067 0.0227
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.002 0.0026 0.0345
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0027 0.0046 0.0149
Schistosoma mansoni glutaminase 0.0401 0.1118 0.7195
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0246
Echinococcus granulosus lysyl tRNA synthetase 0.0022 0.0031 0.0124
Brugia malayi polk-prov protein 0.0029 0.0051 0.0071
Brugia malayi DNA topoisomerase III beta-1 0.0018 0.0019 0.0027
Brugia malayi AMP-binding enzyme family protein 0.0019 0.0023 0.0031
Entamoeba histolytica DNA (cytosine-5)-methyltransferase, putative 0.0014 0.0008 0.0003
Echinococcus multilocularis ecdysone induced protein 78C 0.0024 0.0036 0.0057
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0048 0.0106 0.0429
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0059 0.0137 0.0481
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0014 0.0008 0.0033
Echinococcus granulosus g protein coupled receptor 0.0022 0.003 0.0122
Trichomonas vaginalis sugar transporter, putative 0.0035 0.0067 0.0505
Echinococcus granulosus neuropeptides capa receptor 0.0022 0.003 0.0122
Plasmodium falciparum flap endonuclease 1 0.0047 0.0103 0.0354
Brugia malayi hypothetical protein 0.0067 0.016 0.022
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0062 0.0145 0.02
Trichomonas vaginalis sugar transporter, putative 0.0018 0.002 0.0131
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0012 0.0004 0.0025
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0039 0.0081 0.0111

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 150 nM Inhibition of HDAC1 (mean IC50) ChEMBL. 16987657
IC50 (binding) = 150 nM Inhibition of HDAC1 (mean IC50) ChEMBL. 16987657
IC50 (functional) = 1300 nM Inhibition of HeLa cell proliferation ChEMBL. 16987657
IC50 (functional) = 1300 nM Inhibition of HeLa cell proliferation ChEMBL. 16987657

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 16987657

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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