Detailed information for compound 377821

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 3993.48 | Formula: C182H283N47O54
  • H donors: 56 H acceptors: 55 LogP: -5.07 Rotable bonds: 174
    Rule of 5 violations (Lipinski): 4
  • SMILES: CCCCCCCCCCCCCCCCCC(=O)NC(C(=O)O)CCC(=O)NCCCCC(C(=O)O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](C(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2c1cccc2)NC(=O)[C@@H](NC(=O)[C@H]([C@H](CC)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](C(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]([C@H](O)C)NC(=O)[C@@H](NC(=O)[C@H]([C@H](O)C)NC(=O)CNC(=O)[C@@H](NC(=O)CNC(=O)[C@H](Cc1nc[nH]c1)N)CCC(=O)O)Cc1ccccc1)CO)CC(=O)O)CO)CO)Cc1ccc(cc1)O)CC(C)C)CCC(=O)O)CCC(=O)N)C)C)CCCN=C(N)N)CCC(=O)O)Cc1ccccc1)C)CC(C)C)CCCN=C(N)N)CCCN=C(N)N)CCC(=O)O
  • InChi: 1S/C182H283N47O54/c1-17-19-20-21-22-23-24-25-26-27-28-29-30-31-38-56-136(238)208-123(179(282)283)62-68-135(237)192-73-42-41-52-122(178(280)281)214-161(263)120(65-71-143(247)248)211-159(261)115(54-44-75-194-181(187)188)205-138(240)88-198-155(257)114(53-43-74-193-180(185)186)213-173(275)146(97(7)8)226-166(268)125(78-96(5)6)217-165(267)129(82-108-85-196-113-51-40-39-50-111(108)113)215-153(255)102(14)204-175(277)148(99(11)18-2)228-167(269)127(79-105-46-34-32-35-47-105)218-162(264)121(66-72-144(249)250)212-160(262)116(55-45-76-195-182(189)190)209-152(254)101(13)202-151(253)100(12)203-158(260)119(61-67-134(184)236)207-139(241)89-199-157(259)118(64-70-142(245)246)210-163(265)124(77-95(3)4)216-164(266)126(81-107-57-59-110(235)60-58-107)219-170(272)131(91-230)222-172(274)133(93-232)223-174(276)147(98(9)10)227-169(271)130(84-145(251)252)220-171(273)132(92-231)224-177(279)150(104(16)234)229-168(270)128(80-106-48-36-33-37-49-106)221-176(278)149(103(15)233)225-140(242)90-200-156(258)117(63-69-141(243)244)206-137(239)87-197-154(256)112(183)83-109-86-191-94-201-109/h32-37,39-40,46-51,57-60,85-86,94-104,112,114-133,146-150,196,230-235H,17-31,38,41-45,52-56,61-84,87-93,183H2,1-16H3,(H2,184,236)(H,191,201)(H,192,237)(H,197,256)(H,198,257)(H,199,259)(H,200,258)(H,202,253)(H,203,260)(H,204,277)(H,205,240)(H,206,239)(H,207,241)(H,208,238)(H,209,254)(H,210,265)(H,211,261)(H,212,262)(H,213,275)(H,214,263)(H,215,255)(H,216,266)(H,217,267)(H,218,264)(H,219,272)(H,220,273)(H,221,278)(H,222,274)(H,223,276)(H,224,279)(H,225,242)(H,226,268)(H,227,271)(H,228,269)(H,229,270)(H,243,244)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,280,281)(H,282,283)(H4,185,186,193)(H4,187,188,194)(H4,189,190,195)/t99-,100-,101-,102-,103+,104+,112-,114-,115-,116-,117-,118-,119-,120-,121-,122?,123?,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,146-,147-,148-,149-,150-/m0/s1
  • InChiKey: OBYDFHNDLPKIHP-CPSAFKBDSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus peptide allatostatin:somatostatin 0.2316 0.5513 0.7173
Onchocerca volvulus 0.0031 0.0034 0.0059
Loa Loa (eye worm) hypothetical protein 0.0078 0.0147 0.0265
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0017 0.0001 0.0002
Leishmania major beta tubulin 0.0054 0.009 0.0222
Plasmodium falciparum dihydroorotate dehydrogenase 0.0143 0.0303 0.0796
Echinococcus granulosus survival motor neuron protein 1 0.1 0.2357 0.3067
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0017 0.0002 0.0003
Echinococcus granulosus tubulin alpha 3 chain 0.0064 0.0113 0.0147
Echinococcus granulosus Niemann Pick C1 protein 0.0518 0.1203 0.1565
Leishmania major hypothetical protein, conserved 0.0025 0.0021 0.0053
Loa Loa (eye worm) hypothetical protein 0.0125 0.0261 0.0471
Loa Loa (eye worm) IMP dehydrogenase 1 0.1707 0.4053 0.7351
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0033 0.0039 0.0069
Leishmania major delta tubulin, putative 0.0017 0.0001 0.0002
Brugia malayi nuclear receptor NHR-88 0.0017 0.0002 0.0003
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0037 0.0049 0.012
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0022
Trypanosoma brucei epsilon tubulin 0.0039 0.0053 0.0132
Echinococcus granulosus Protein patched homolog 1 0.0156 0.0333 0.0434
Leishmania major hypothetical protein, conserved 0.0101 0.0203 0.0502
Trypanosoma brucei tubulin gamma chain 0.0039 0.0053 0.0132
Echinococcus granulosus tubulin alpha 0.0039 0.0053 0.0069
Mycobacterium ulcerans beta-lactamase 0.0039 0.0053 0.0131
Brugia malayi Endoplasmin precursor 0.0025 0.002 0.0037
Echinococcus multilocularis FTZ F1 alpha 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0022
Echinococcus granulosus 7tm_1 domain containing protein 0.2316 0.5513 0.7173
Brugia malayi Dopamine receptor protein 2 0.2316 0.5513 1
Schistosoma mansoni growth hormone secretagogue receptor 0.2316 0.5513 1
Brugia malayi MAP kinase sur-1 0.0051 0.0083 0.0151
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0107 0.0264
Loa Loa (eye worm) hypothetical protein 0.0101 0.0202 0.0365
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0004 0.0077
Trypanosoma brucei low molecular weight protein tyrosine phosphatase, putative 0.0041 0.0058 0.0143
Loa Loa (eye worm) hypothetical protein 0.0039 0.0053 0.0095
Echinococcus granulosus FTZ F1 alpha 0.0017 0.0002 0.0002
Schistosoma mansoni nuclear hormone receptor 0.0017 0.0002 0.0003
Echinococcus multilocularis carbonic anhydrase 0.0547 0.1272 0.1272
Trichomonas vaginalis tubulin beta chain, putative 0.0064 0.0113 0.1975
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.1365 0.3234 0.3234
Trypanosoma brucei heat shock protein 90, putative 0.0025 0.002 0.005
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0022 0.0013 0.022
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0017 0.0002 0.0003
Leishmania major heat shock protein 83-1 0.0025 0.002 0.005
Echinococcus granulosus neuroligin 0.0101 0.0202 0.0263
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.0223 0.2681
Loa Loa (eye worm) endoplasmin 0.0025 0.002 0.0036
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.1707 0.4053 1
Wolbachia endosymbiont of Brugia malayi hemolysin 0.0101 0.0203 0.0502
Brugia malayi MH1 domain containing protein 0.0028 0.0027 0.0049
Loa Loa (eye worm) acetylcholinesterase 1 0.0596 0.139 0.2521
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0022
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0044 0.0066 0.012
Plasmodium vivax tubulin alpha chain, putative 0.0064 0.0113 0.0296
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0088 0.0173 0.0426
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0088 0.0173 0.0426
Leishmania major heat shock protein 83-1 0.0025 0.002 0.005
Echinococcus multilocularis tubulin epsilon chain 0.0039 0.0053 0.0053
Trichomonas vaginalis chromobox protein, putative 0.007 0.0129 0.225
Onchocerca volvulus 0.0044 0.0066 0.0116
Mycobacterium tuberculosis Conserved protein 0.0039 0.0055 0.0135
Loa Loa (eye worm) phosphofructokinase 0.0109 0.0223 0.0403
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0037 0.0049 0.012
Mycobacterium ulcerans hypothetical protein 0.0101 0.0203 0.0502
Schistosoma mansoni neuroligin 3 (S09 family) 0.0101 0.0202 0.0367
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0053 0.0096
Loa Loa (eye worm) GMP reductase 0.0709 0.1661 0.3012
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0021
Echinococcus multilocularis Tubulin beta 2C chain 0.0054 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0017 0.0002 0.0002
Trypanosoma brucei glycosyl hydrolase-like protein 0.0022 0.0013 0.0031
Loa Loa (eye worm) neuropeptide F receptor 0.2316 0.5513 1
Echinococcus multilocularis Tubulin alpha 1 chain 0.0064 0.0113 0.0113
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0037 0.0049 0.0049
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0036 0.0047 0.0047
Toxoplasma gondii propionate-CoA ligase 0.0037 0.0049 0.012
Plasmodium falciparum tubulin gamma chain 0.0039 0.0053 0.014
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0053 0.0131
Wolbachia endosymbiont of Brugia malayi dihydroorotate dehydrogenase 2 0.0143 0.0303 0.0748
Loa Loa (eye worm) steroid hormone receptor 0.0017 0.0002 0.0002
Chlamydia trachomatis GutQ/KpsF family sugar-phosphate isomerase 0.0101 0.0203 1
Brugia malayi Steroid receptor seven-up type 2 0.0017 0.0002 0.0003
Leishmania major heat shock protein 83-1 0.0025 0.002 0.005
Brugia malayi Patched related family protein 12 0.0022 0.0013 0.0024
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0049 0.0078 0.0193
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0022 0.0013 0.0227
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB3 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.0896 0.2109 0.5204
Brugia malayi AMP-binding enzyme family protein 0.0125 0.0261 0.0473
Brugia malayi beta-lactamase family protein 0.0039 0.0053 0.0096
Giardia lamblia Heat shock protein HSP 90-alpha 0.0025 0.002 0.0371
Onchocerca volvulus 0.0037 0.0049 0.0085
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0363 0.083 1
Trypanosoma cruzi heat shock protein 85, putative 0.0025 0.002 0.005
Brugia malayi Carboxylesterase family protein 0.0101 0.0202 0.0367
Mycobacterium leprae Probable cystathionine beta-synthase CBS (Serine sulfhydrase) (Beta-thionase) (Hemoprotein H-450) 0.0101 0.0203 0.05
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0053 0.0131
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0017 0.0002 0.0002
Onchocerca volvulus 0.2316 0.5513 1
Loa Loa (eye worm) tubulin alpha chain 0.0064 0.0113 0.0203
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0036 0.0047 0.0047
Schistosoma mansoni retinoic acid receptor RXR 0.0017 0.0002 0.0003
Brugia malayi MH2 domain containing protein 0.0028 0.0027 0.0049
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0053 0.0087 0.0227
Schistosoma mansoni hypothetical protein 0.0239 0.0533 0.0967
Wolbachia endosymbiont of Brugia malayi Mg2+/Co2+ transporter 0.0101 0.0203 0.0502
Loa Loa (eye worm) runx1 0.0039 0.0055 0.0097
Echinococcus multilocularis carbonic anhydrase 0.0547 0.1272 0.1272
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.1164 0.2752 0.679
Schistosoma mansoni tubulin subunit alpha 0.0064 0.0113 0.0205
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0031 0.1406
Onchocerca volvulus 0.0101 0.0202 0.0363
Trichomonas vaginalis tubulin alpha chain, putative 0.0039 0.0053 0.0933
Mycobacterium tuberculosis Cell division protein FtsZ 0.0017 0.0001 0.0002
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0017 0.0002 0.0002
Echinococcus multilocularis somatostatin receptor 0.2316 0.5513 0.5513
Loa Loa (eye worm) tubulin alpha chain 0.0064 0.0113 0.0203
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0002
Leishmania major alpha tubulin 0.0064 0.0113 0.0279
Echinococcus multilocularis RUN 0.0239 0.0533 0.0533
Trypanosoma cruzi epsilon tubulin, putative 0.0039 0.0053 0.0132
Onchocerca volvulus 0.2316 0.5513 1
Loa Loa (eye worm) carboxylesterase 0.0101 0.0202 0.0365
Echinococcus multilocularis musashi 0.0058 0.0099 0.0099
Brugia malayi Heterochromatin protein 1 0.007 0.0129 0.0233
Loa Loa (eye worm) hypothetical protein 0.0039 0.0055 0.0098
Echinococcus granulosus tm gpcr rhodopsin 0.2316 0.5513 0.7173
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0017 0.0002 0.0003
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0053 0.0087 0.0214
Echinococcus multilocularis tubulin alpha chain 0.0064 0.0113 0.0113
Mycobacterium tuberculosis Conserved protein 0.0101 0.0203 0.0502
Plasmodium falciparum tubulin epsilon chain, putative 0.0039 0.0053 0.014
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0049 0.0078 0.0078
Plasmodium vivax inosine-5'-monophosphate dehydrogenase, putative 0.1605 0.381 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.2316 0.5513 1
Trichomonas vaginalis tubulin beta chain, putative 0.0064 0.0113 0.1975
Trypanosoma cruzi importin beta-1 subunit, putative 0.0017 0 0.0001
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0051 0.0083 0.015
Echinococcus granulosus RUN 0.0239 0.0533 0.0693
Echinococcus multilocularis carbonic anhydrase II 0.1164 0.2752 0.2752
Onchocerca volvulus 0.2316 0.5513 1
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0132 0.0277 0.4849
Brugia malayi Tubulin beta-1 chain 0.0054 0.009 0.0163
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0547 0.1272 0.2305
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0219 0.0487 0.0882
Plasmodium falciparum carbonic anhydrase 0.0547 0.1272 0.3338
Brugia malayi hypothetical protein 0.0182 0.0396 0.0718
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0053 0.0129
Mycobacterium leprae Secreted antigen 85A FbpA (mycolyl transferase 85A) (fibronectin-binding protein A) (antigen 85 complex A) 0.0039 0.0055 0.0133
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0101 0.0202 0.3536
Mycobacterium tuberculosis Hypoxic response protein 1 Hrp1 0.0101 0.0203 0.0502
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0022
Schistosoma mansoni carbonic anhydrase-related 0.0547 0.1272 0.2307
Brugia malayi ancient conserved domain protein 2 0.0101 0.0203 0.0369
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0049 0.012
Brugia malayi AKH receptor 0.2316 0.5513 1
Echinococcus multilocularis tubulin subunit TubB 0.0064 0.0113 0.0113
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0032 0.0036 0.009
Echinococcus granulosus SNF4:AMP activated protein kinase gamma subunit 0.0101 0.0203 0.0265
Leishmania major alpha tubulin 0.0064 0.0113 0.0279
Brugia malayi Patched family protein 0.0022 0.0013 0.0024
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0058 0.0143
Leishmania major heat shock protein 83-1 0.0025 0.002 0.005
Onchocerca volvulus 0.0255 0.0571 0.1033
Leishmania major alpha tubulin 0.0064 0.0113 0.0279
Treponema pallidum heat shock protein 90 0.002 0.0008 0.0366
Loa Loa (eye worm) hypothetical protein 0.0308 0.0699 0.1267
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0109 0.0223 0.055
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.2316 0.5513 1
Toxoplasma gondii heat shock protein 90, putative 0.0025 0.002 0.005
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0075 0.0134
Onchocerca volvulus Protein patched homolog 0.0022 0.0013 0.0021
Wolbachia endosymbiont of Brugia malayi Mg/Co/Ni transporter MgtE 0.0101 0.0203 0.0502
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.0223 0.3898
Mycobacterium ulcerans heat shock protein 90 0.002 0.0008 0.002
Schistosoma mansoni coup transcription factor 0.0017 0.0002 0.0003
Loa Loa (eye worm) MH2 domain-containing protein 0.0406 0.0933 0.1692
Schistosoma mansoni neuropeptide receptor 0.2316 0.5513 1
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0094 0.0185 0.0456
Leishmania major chloride channel protein, putative 0.0101 0.0203 0.0502
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0031 0.0548
Toxoplasma gondii ABC1 family protein 0.0039 0.0053 0.0131
Schistosoma mansoni inosine-5-monophosphate dehydrogenase 0.1707 0.4053 0.7351
Schistosoma mansoni tubulin subunit beta 0.0054 0.009 0.0163
Brugia malayi hypothetical protein 0.2316 0.5513 1
Onchocerca volvulus 0.0022 0.0013 0.0021
Brugia malayi tubulin alpha-2 chain 0.0064 0.0113 0.0205
Echinococcus granulosus H:Cl exchange transporter 4 0.0101 0.0203 0.0265
Echinococcus granulosus lamin 0.0058 0.0099 0.0129
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0049 0.012
Trypanosoma brucei heat shock protein, putative 0.0025 0.002 0.005
Echinococcus multilocularis Tubulin beta 2C chain 0.0054 0.009 0.009
Echinococcus granulosus carboxylesterase 5A 0.0596 0.139 0.1809
Brugia malayi hypothetical protein 0.2316 0.5513 1
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.2316 0.5513 0.5513
Brugia malayi Dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.0143 0.0303 0.055
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0022 0.0013 0.0031
Schistosoma mansoni microtubule-associated protein tau 0.0664 0.1552 0.2816
Brugia malayi Patched family protein 0.0022 0.0013 0.0024
Loa Loa (eye worm) heterochromatin protein 1 0.007 0.0129 0.0232
Echinococcus multilocularis rhodopsin orphan GPCR 0.2316 0.5513 0.5513
Echinococcus multilocularis heat shock protein 0.0025 0.002 0.002
Trichomonas vaginalis maltase-glucoamylase, putative 0.0022 0.0013 0.022
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0596 0.139 0.2522
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0053 0.0929
Schistosoma mansoni tubulin subunit epsilon 0.0039 0.0053 0.0097
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Trypanosoma brucei beta tubulin 0.0054 0.009 0.0222
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0109 0.0223 0.055
Loa Loa (eye worm) G-protein coupled receptor 0.2316 0.5513 1
Schistosoma mansoni tubulin subunit alpha 0.0064 0.0113 0.0205
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0018 0.0002 0.0003
Brugia malayi AMP-binding enzyme family protein 0.0037 0.0049 0.0088
Loa Loa (eye worm) hypothetical protein 0.0039 0.0053 0.0095
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.006 0.0105 0.0105
Leishmania major heat shock protein 83-1 0.0025 0.002 0.005
Trichomonas vaginalis tubulin, putative 0.0054 0.009 0.1577
Brugia malayi Intermediate filament tail domain containing protein 0.0058 0.0099 0.018
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0017 0.0002 0.0002
Schistosoma mansoni carbonic anhydrase-related 0.0547 0.1272 0.2307
Echinococcus granulosus heat shock protein 0.0025 0.002 0.0026
Echinococcus multilocularis muscleblind protein 1 0.0126 0.0263 0.0263
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.0039 0.0055 0.0135
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.006 0.0105 0.0105
Echinococcus granulosus mitogen activated protein kinase 0.0051 0.0083 0.0109
Loa Loa (eye worm) patched family protein 0.0022 0.0013 0.0022
Echinococcus granulosus hypothetical protein 0.2316 0.5513 0.7173
Entamoeba histolytica heat shock protein 90, putative 0.0025 0.002 0.024
Echinococcus multilocularis para nitrobenzyl esterase 0.0101 0.0202 0.0202
Trypanosoma cruzi chloride channel protein, putative 0.0101 0.0203 0.0502
Onchocerca volvulus 0.0101 0.0202 0.0363
Brugia malayi Serotonin/octopamine receptor family protein 7 0.2316 0.5513 1
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0053 0.0131
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0058 0.01 0.0181
Schistosoma mansoni hypothetical protein 0.0547 0.1272 0.2307
Trypanosoma brucei heat shock protein, putative 0.0025 0.002 0.005
Onchocerca volvulus 0.0126 0.0263 0.0474
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0004 0.0077
Mycobacterium ulcerans carboxylesterase, LipT 0.0101 0.0202 0.0499
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Brugia malayi nuclear hormone receptor 0.0017 0.0002 0.0003
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.002 0.0008 0.0011
Loa Loa (eye worm) tubulin gamma chain 0.0039 0.0053 0.0095
Trypanosoma cruzi tubulin delta chain 0.0017 0.0001 0.0002
Trypanosoma brucei beta tubulin 0.0054 0.009 0.0222
Onchocerca volvulus 0.2316 0.5513 1
Mycobacterium ulcerans 6-phosphofructokinase 0.0109 0.0223 0.055
Giardia lamblia Epsilon tubulin 0.0017 0.0001 0.0014
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Onchocerca volvulus 0.0204 0.0449 0.0812
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0049 0.012
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0017 0.0002 0.0002
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0101 0.0202 0.0202
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0101 0.0202 0.0367
Leishmania major trypanothione reductase 0.0048 0.0075 0.0184
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.3222 0.7686 0.7686
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.1164 0.2752 0.499
Mycobacterium ulcerans acyl-CoA synthetase 0.0125 0.0261 0.0643
Schistosoma mansoni tubulin subunit beta 0.0054 0.009 0.0163
Toxoplasma gondii chloride transporter, chloride channel (ClC) family protein 0.0101 0.0203 0.0502
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0053 0.0131
Echinococcus multilocularis sterol regulatory element binding protein 0.0156 0.0333 0.0333
Onchocerca volvulus 0.0125 0.0261 0.047
Echinococcus multilocularis expressed conserved protein 0.0341 0.0777 0.0777
Mycobacterium tuberculosis Conserved protein 0.0039 0.0053 0.0131
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0083 0.146
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0049 0.0078 0.0193
Echinococcus multilocularis neuroligin 0.0101 0.0202 0.0202
Echinococcus multilocularis rhodopsin orphan GPCR 0.2316 0.5513 0.5513
Echinococcus multilocularis H(+):Cl() exchange transporter 3 0.0101 0.0203 0.0203
Brugia malayi Tubulin alpha chain 0.0017 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0028 0.0027 0.0048
Mycobacterium leprae Probable inosine-5'-monophosphate dehydrogenase GuaB2 (IMP dehydrogenase) (IMPDH) (IMPD) 0.1707 0.4053 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0039 0.0096
Schistosoma mansoni cpg binding protein 0.0032 0.0037 0.0067
Trypanosoma cruzi AMP-activated protein kinase, gamma regulatory subunit 0.0101 0.0203 0.0502
Trypanosoma brucei heat shock protein, putative 0.0025 0.002 0.005
Echinococcus granulosus cpg binding protein 0.0032 0.0037 0.0048
Toxoplasma gondii beta-1 tubulin, putative 0.0054 0.009 0.0222
Brugia malayi Cell division protein ftsZ 0.0017 0.0001 0.0001
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0053 0.0929
Echinococcus granulosus rhodopsin orphan GPCR 0.2316 0.5513 0.7173
Trypanosoma brucei zeta tubulin, putative 0.0017 0.0001 0.0002
Giardia lamblia Delta tubulin 0.0017 0.0001 0.0014
Echinococcus granulosus 5' AMP activated protein kinase subunit gamma 0.0101 0.0203 0.0265
Leishmania major alpha tubulin 0.0064 0.0113 0.0279
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Brugia malayi Serotonin receptor 0.2316 0.5513 1
Leishmania major heat shock protein 83-1 0.0025 0.002 0.005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0017 0.0002 0.0002
Brugia malayi jmjC domain containing protein 0.0061 0.0107 0.0193
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0053 0.0087 0.0214
Loa Loa (eye worm) 6-phosphofructokinase 0.0109 0.0223 0.0403
Echinococcus multilocularis G-protein coupled receptor, putative 0.2316 0.5513 0.5513
Brugia malayi Glycosyl hydrolases family 31 protein 0.0022 0.0013 0.0023
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0037 0.0049 0.012
Mycobacterium ulcerans hypothetical protein 0.0125 0.0261 0.0643
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0062 0.1082
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0132 0.0277 0.4849
Echinococcus granulosus tm gpcr rhodopsin 0.2316 0.5513 0.7173
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0107 0.0107
Toxoplasma gondii alpha tubulin TUBA1 0.0064 0.0113 0.0279
Brugia malayi MH1 domain containing protein 0.0028 0.0027 0.0049
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Echinococcus multilocularis acetylcholinesterase 0.0596 0.139 0.139
Giardia lamblia DNA repair protein RAD52 0.0245 0.0549 1
Loa Loa (eye worm) hypothetical protein 0.0101 0.0202 0.0365
Echinococcus granulosus acetylcholinesterase 0.0596 0.139 0.1809
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0101 0.0202 0.0367
Brugia malayi ORL1-like opioid receptor 0.2316 0.5513 1
Echinococcus granulosus tumor protein p63 0.034 0.0776 0.1009
Echinococcus multilocularis neuropeptide receptor 0.2316 0.5513 0.5513
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB2 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.1707 0.4053 1
Schistosoma mansoni chloride channel protein 0.0101 0.0203 0.0369
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0083 0.146
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0049 0.0078 0.0078
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0107 0.0194
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0022
Trypanosoma brucei heat shock protein, putative 0.0025 0.002 0.005
Onchocerca volvulus 0.2316 0.5513 1
Echinococcus multilocularis chromobox protein 1 0.007 0.0129 0.0129
Schistosoma mansoni loxhd1 0.0239 0.0533 0.0967
Giardia lamblia Grp94/Hsp90 0.002 0.0008 0.0149
Onchocerca volvulus 0.0313 0.071 0.1285
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.0143 0.0303 0.0748
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.2316 0.5513 1
Echinococcus multilocularis Tubulin beta 2C chain 0.0054 0.009 0.009
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0056 0.0094 0.165
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0037 0.0049 0.0118
Loa Loa (eye worm) hypothetical protein 0.0094 0.0185 0.0334
Brugia malayi 6-phosphofructokinase 0.0109 0.0223 0.0404
Echinococcus granulosus tubulin alpha 1C chain 0.0064 0.0113 0.0147
Brugia malayi tubulin alpha chain - mouse 0.0064 0.0113 0.0205
Schistosoma mansoni tubulin subunit beta 0.0054 0.009 0.0163
Brugia malayi CLC chloride channel protein 0.0101 0.0203 0.0369
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0022
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0037 0.0049 0.012
Echinococcus multilocularis carboxylesterase 5A 0.0596 0.139 0.139
Mycobacterium ulcerans secreted antigen 85-C FbpC 0.0926 0.2181 0.5382
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0017 0.0002 0.0002
Echinococcus granulosus tubulin beta 4A class IVa 0.0054 0.009 0.0117
Brugia malayi AMP-binding enzyme family protein 0.0037 0.0049 0.0088
Toxoplasma gondii CBS family protein 0.0101 0.0203 0.0502
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0017 0.0002 0.0002
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.2316 0.5513 1
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Echinococcus multilocularis acetylcholinesterase 0.0596 0.139 0.139
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Trypanosoma brucei alpha tubulin 0.0064 0.0113 0.0279
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0059 0.0102 0.0133
Echinococcus granulosus allatostatin A receptor 0.2316 0.5513 0.7173
Loa Loa (eye worm) hypothetical protein 0.1 0.2357 0.4275
Chlamydia trachomatis CBS domain-containing protein 0.0101 0.0203 1
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0101 0.0202 0.0367
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0037 0.0049 0.012
Mycobacterium ulcerans acetyl-CoA synthetase 0.0037 0.0049 0.012
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Brugia malayi Glycosyl hydrolases family 31 protein 0.0263 0.0591 0.1071
Schistosoma mansoni hypothetical protein 0.2316 0.5513 1
Echinococcus multilocularis tubulin alpha chain 0.0064 0.0113 0.0113
Echinococcus granulosus G protein coupled receptor 139 0.2316 0.5513 0.7173
Brugia malayi G-protein coupled receptor 0.2316 0.5513 1
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.2316 0.5513 0.5513
Echinococcus granulosus inosine 5' monophosphate dehydrogenase 2 0.1707 0.4053 0.5273
Brugia malayi Tubulin gamma chain 0.0039 0.0053 0.0097
Echinococcus granulosus carbonic anhydrase 0.0547 0.1272 0.1654
Loa Loa (eye worm) BEN-1 protein 0.0054 0.009 0.0162
Trypanosoma brucei Voltage-gated Chloride channel Like 3 0.0101 0.0203 0.0502
Schistosoma mansoni tubulin subunit delta 0.0017 0.0001 0.0001
Entamoeba histolytica tubulin alpha-1 chain 0.0064 0.0113 0.1356
Onchocerca volvulus 0.0022 0.0013 0.0021
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0053 0.0131
Echinococcus multilocularis transfer RNA-Lys 0.0043 0.0065 0.0065
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0017 0.0002 0.0002
Trichomonas vaginalis alpha-glucosidase, putative 0.0022 0.0013 0.022
Brugia malayi Patched family protein 0.0022 0.0013 0.0024
Plasmodium falciparum acyl-CoA synthetase 0.0094 0.0185 0.0485
Schistosoma mansoni chromobox protein 0.007 0.0129 0.0233
Onchocerca volvulus 0.2316 0.5513 1
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0053 0.0131
Giardia lamblia Heat shock protein HSP 90-alpha 0.002 0.0008 0.0149
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0022
Leishmania major 4-coumarate:coa ligase-like protein 0.0125 0.0261 0.0643
Leishmania major acetyl-CoA synthetase, putative 0.0037 0.0049 0.012
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.2316 0.5513 0.7173
Echinococcus granulosus tubulin epsilon chain 0.0039 0.0053 0.0069
Loa Loa (eye worm) tubulin beta-4 chain 0.0054 0.009 0.0162
Echinococcus granulosus neutral alpha glucosidase AB 0.0058 0.01 0.013
Echinococcus granulosus arachidonate 5 lipoxygenase 0.1365 0.3234 0.4207
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0053 0.0087 0.1577
Echinococcus granulosus rhodopsin orphan GPCR 0.2316 0.5513 0.7173
Schistosoma mansoni patched 1 0.0156 0.0333 0.0605
Echinococcus multilocularis rhodopsin orphan GPCR 0.2316 0.5513 0.5513
Mycobacterium ulcerans lipase LipD 0.0039 0.0053 0.0131
Loa Loa (eye worm) TYRA-2 protein 0.2316 0.5513 1
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0037 0.0049 0.012
Echinococcus granulosus tubulin alpha 1C chain 0.0064 0.0113 0.0147
Schistosoma mansoni alpha glucosidase 0.0058 0.01 0.0182
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.002 0.0008 0.0018
Echinococcus granulosus tubulin beta 1 chain 0.0054 0.009 0.0117
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.1164 0.2752 0.4991
Brugia malayi gonadotropin-releasing hormone receptor 2 0.2316 0.5513 1
Echinococcus granulosus Tubulin beta 2C chain 0.0054 0.009 0.0117
Echinococcus granulosus AMP activated protein kinase gamma regulatory 0.0101 0.0203 0.0265
Leishmania major beta tubulin 0.0054 0.009 0.0222
Schistosoma mansoni opsin-like receptor 0.2316 0.5513 1
Echinococcus multilocularis Tubulin alpha 1 chain 0.0064 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0033 0.0039 0.007
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0053 0.0131
Mycobacterium ulcerans hypothetical protein 0.0039 0.0053 0.0131
Echinococcus multilocularis protein dispatched 1 0.0178 0.0386 0.0386
Brugia malayi GMP reductase 0.0709 0.1661 0.3013
Echinococcus granulosus tubulin alpha chain 0.0064 0.0113 0.0147
Onchocerca volvulus 0.0022 0.0013 0.0021
Loa Loa (eye worm) follicle stimulating hormone receptor 0.2316 0.5513 1
Schistosoma mansoni neuropeptide F-like receptor 0.2316 0.5513 1
Brugia malayi Patched family protein 0.0022 0.0013 0.0024
Schistosoma mansoni amine GPCR 0.2316 0.5513 1
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0101 0.0203 0.0502
Loa Loa (eye worm) hypothetical protein 0.0101 0.0203 0.0368
Onchocerca volvulus Putative GMP reductase 0.0709 0.1661 0.3011
Schistosoma mansoni intermediate filament proteins 0.0058 0.0099 0.018
Brugia malayi Carboxylesterase family protein 0.0596 0.139 0.2522
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0021 0.0053
Echinococcus granulosus snurportin 1 0.0219 0.0487 0.0633
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0033 0.0039 0.005
Schistosoma mansoni smad 0.0028 0.0027 0.0049
Entamoeba histolytica tubulin gamma chain 0.0039 0.0053 0.0638
Schistosoma mansoni 6-phosphofructokinase 0.0109 0.0223 0.0404
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.2316 0.5513 1
Trypanosoma brucei AMP-activated protein kinase, gamma regulatory subunit 0.0101 0.0203 0.0502
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0058 0.01 0.0247
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0037 0.0049 0.012
Loa Loa (eye worm) hypothetical protein 0.0094 0.0185 0.0334
Echinococcus granulosus chromobox protein 1 0.007 0.0129 0.0167
Plasmodium vivax importin-beta 2, putative 0.0021 0.001 0.0026
Echinococcus granulosus biogenic amine 5HT receptor 0.2316 0.5513 0.7173
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Brugia malayi Serotonin receptor 0.2316 0.5513 1
Mycobacterium ulcerans cystathionine beta-synthase 0.0101 0.0203 0.0502
Mycobacterium ulcerans inosine 5'-monophosphate dehydrogenase 0.1707 0.4053 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0022
Trypanosoma brucei dihydroorotate dehydrogenase (fumarate) 0.0143 0.0303 0.0748
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0017 0.0002 0.0003
Brugia malayi sulfakinin receptor protein 0.2316 0.5513 1
Schistosoma mansoni thyroid hormone receptor 0.0017 0.0002 0.0003
Brugia malayi Zinc finger, C2H2 type family protein 0.0056 0.0094 0.0171
Trichomonas vaginalis tubulin gamma chain, putative 0.0039 0.0053 0.0933
Loa Loa (eye worm) tubulin alpha 2 0.0025 0.002 0.0035
Brugia malayi AMP-binding enzyme family protein 0.0037 0.0049 0.0088
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0017 0.0002 0.0003
Echinococcus multilocularis tubulin gamma 1 chain 0.0039 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0037 0.0049 0.0087
Echinococcus multilocularis g protein coupled receptor 0.2316 0.5513 0.5513
Onchocerca volvulus 0.0101 0.0202 0.0363
Onchocerca volvulus 0.0037 0.0049 0.0085
Onchocerca volvulus Huntingtin homolog 0.0182 0.0396 0.0715
Onchocerca volvulus 0.0039 0.0053 0.0093
Echinococcus granulosus mitogen activated protein kinase 3 0.0051 0.0083 0.0109
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0031 0.0082
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0055 0.0957
Plasmodium vivax patched family protein, putative 0.0022 0.0013 0.0035
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) 0.0091 0.0179 0.0443
Echinococcus multilocularis lamin dm0 0.0058 0.0099 0.0099
Schistosoma mansoni myosin xvIII 0.2316 0.5513 1
Echinococcus multilocularis survival motor neuron protein 1 0.1 0.2357 0.2357
Schistosoma mansoni tubulin subunit beta 0.0054 0.009 0.0163
Trichomonas vaginalis alpha-glucosidase, putative 0.0022 0.0013 0.022
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0049 0.0078 0.0205
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0088 0.0173 0.0426
Echinococcus multilocularis rhodopsin orphan GPCR 0.2316 0.5513 0.5513
Echinococcus granulosus smad 0.0028 0.0027 0.0035
Echinococcus granulosus somatostatin receptor 0.2316 0.5513 0.7173
Schistosoma mansoni tubulin subunit gamma 0.0039 0.0053 0.0097
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.2316 0.5513 0.5513
Loa Loa (eye worm) hypothetical protein 0.0125 0.0261 0.0471
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0022
Brugia malayi glutathione reductase 0.0048 0.0075 0.0135
Loa Loa (eye worm) hypothetical protein 0.0547 0.1272 0.2305
Brugia malayi hypothetical protein 0.0308 0.0699 0.1268
Brugia malayi Thioredoxin reductase 0.0048 0.0075 0.0135
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0037 0.0049 0.0087
Echinococcus multilocularis Niemann Pick C1 protein 0.0363 0.083 0.083
Echinococcus granulosus neuropeptide receptor A26 0.2316 0.5513 0.7173
Loa Loa (eye worm) hypothetical protein 0.0037 0.0049 0.0087
Echinococcus multilocularis neuropeptide Y receptor 0.2316 0.5513 0.5513
Onchocerca volvulus 0.0058 0.0099 0.0176
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0053 0.0069
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0017 0 0.0008
Giardia lamblia Kinase, CMGC MAPK 0.0051 0.0083 0.1519
Brugia malayi PAS domain containing protein 0.0059 0.0101 0.0184
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0002
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0017 0.0001 0.0014
Schistosoma mansoni chromobox protein 0.007 0.0129 0.0233
Leishmania major beta tubulin 0.0054 0.009 0.0222
Plasmodium vivax multidomain scavenger receptor, putative 0.0239 0.0533 0.1399
Echinococcus multilocularis dro:myosuppressin receptor 0.2316 0.5513 0.5513
Brugia malayi ecdysteroid receptor 0.0017 0.0002 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0017 0.0002 0.0003
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.2316 0.5513 0.7173
Toxoplasma gondii beta-tubulin, putative 0.0054 0.009 0.0222
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0047 0.0073 0.013
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0245 0.0549 0.6615
Brugia malayi G protein-coupled receptor 0.2316 0.5513 1
Trypanosoma brucei beta tubulin 0.0054 0.009 0.0222
Leishmania major beta tubulin 0.0054 0.009 0.0222
Loa Loa (eye worm) hypothetical protein 0.0101 0.0203 0.0368
Trichomonas vaginalis tubulin epsilon chain, putative 0.0054 0.009 0.1577
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0017 0.0002 0.0002
Leishmania major beta tubulin 0.0054 0.009 0.0222
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0042 0.006 0.1056
Leishmania major beta tubulin 0.0054 0.009 0.0222
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0033 0.0058
Echinococcus granulosus H:Cl exchange transporter 7 0.0101 0.0203 0.0265
Loa Loa (eye worm) patched family protein 0.0022 0.0013 0.0022
Brugia malayi protein C24B5.3 0.0022 0.0013 0.0024
Trichomonas vaginalis antibiotic synthetase, putative 0.0037 0.0049 0.0851
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0022
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0021 0.0056
Mycobacterium tuberculosis Secreted antigen 85-C FbpC (85C) (antigen 85 complex C) (AG58C) (mycolyl transferase 85C) (fibronectin-binding protein C) 0.0926 0.2181 0.5382
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0075 0.0075
Echinococcus multilocularis tubulin alpha chain 0.0064 0.0113 0.0113
Echinococcus multilocularis H(+):Cl() exchange transporter 7 0.0101 0.0203 0.0203
Loa Loa (eye worm) hypothetical protein 0.0101 0.0202 0.0365
Brugia malayi intermediate filament protein 0.0058 0.0099 0.018
Schistosoma mansoni lipoxygenase 0.0935 0.2203 0.3996
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.0223 0.3898
Trichomonas vaginalis alpha-glucosidase, putative 0.0022 0.0013 0.022
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0001 0.0014
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.1605 0.381 0.94
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0132 0.0277 0.4849
Echinococcus granulosus tubulin alpha chain 0.0064 0.0113 0.0147
Loa Loa (eye worm) transcription factor SMAD2 0.0406 0.0933 0.1692
Loa Loa (eye worm) loechrig isoform VII 0.0101 0.0203 0.0368
Trichomonas vaginalis alpha-glucosidase, putative 0.0022 0.0013 0.022
Brugia malayi G-protein coupled receptor 0.2316 0.5513 1
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0062 0.1082
Giardia lamblia 5-AMP-activated protein kinase, gamma-1 subunit 0.0101 0.0203 0.3707
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0037 0.0049 0.0063
Echinococcus granulosus Tubulin alpha 1 chain 0.0064 0.0113 0.0147
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0017 0.0002 0.0003
Schistosoma mansoni heat shock protein 0.0025 0.002 0.0037
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0037 0.0049 0.012
Plasmodium vivax acetyl-CoA synthetase, putative 0.0037 0.0049 0.0128
Brugia malayi aryl hydrocarbon receptor AHR-1 0.0111 0.0227 0.0411
Brugia malayi Carboxylesterase family protein 0.0596 0.139 0.2522
Schistosoma mansoni tubulin subunit alpha 0.0017 0.0001 0.0001
Schistosoma mansoni alpha tubulin 0.0064 0.0113 0.0205
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0037 0.0049 0.012
Onchocerca volvulus 0.0022 0.0013 0.0021
Leishmania major hypothetical protein, conserved 0.0039 0.0053 0.0131
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0031 0.0082
Trichomonas vaginalis maltase-glucoamylase, putative 0.0058 0.01 0.1755
Echinococcus multilocularis lysosomal alpha glucosidase 0.0263 0.0591 0.0591
Onchocerca volvulus 0.0039 0.0053 0.0093
Plasmodium falciparum importin beta, putative 0.0021 0.001 0.0026
Brugia malayi Esterase D 0.0039 0.0055 0.0099
Brugia malayi bHLH-PAS transcription factor 0.0043 0.0065 0.0117
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Trichomonas vaginalis tubulin gamma chain, putative 0.0054 0.009 0.1577
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0037 0.0049 0.012
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0049 0.012
Brugia malayi neuropeptide F receptor 0.2316 0.5513 1
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0053 0.0929
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0022 0.0013 0.0019
Toxoplasma gondii isocitrate dehydrogenase 0.0049 0.0078 0.0193
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0028 0.0027 0.0049
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.2316 0.5513 1
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.002 0.0008 0.002
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0039 0.0039
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0049 0.0078 0.0205
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0047 0.0073 0.127
Trypanosoma cruzi chloride channel protein, putative 0.0101 0.0203 0.0502
Echinococcus granulosus Niemann Pick C1 protein 0.0363 0.083 0.1079
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0033 0.0039 0.007
Trichomonas vaginalis conserved hypothetical protein 0.0156 0.0333 0.5836
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Schistosoma mansoni hypothetical protein 0.0431 0.0994 0.1802
Leishmania major guanosine monophosphate reductase 0.1707 0.4053 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0002
Mycobacterium tuberculosis Probable dehydrogenase 0.0109 0.0221 0.0545
Schistosoma mansoni survival motor neuron protein 0.0204 0.0449 0.0815
Onchocerca volvulus Huntingtin homolog 0.0182 0.0396 0.0715
Leishmania major 4-coumarate:coa ligase-like protein 0.0125 0.0261 0.0643
Brugia malayi Patched protein homolog 1 0.0022 0.0013 0.0024
Schistosoma mansoni alpha tubulin 0.0064 0.0113 0.0205
Loa Loa (eye worm) hypothetical protein 0.0547 0.1272 0.2305
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0049 0.012
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0051 0.0083 0.0206
Echinococcus multilocularis Tubulin beta 2C chain 0.0054 0.009 0.009
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0037 0.0049 0.012
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.006 0.0105 0.0136
Echinococcus granulosus neuropeptide Y receptor 0.2316 0.5513 0.7173
Echinococcus granulosus tubulin subunit TubB 0.0064 0.0113 0.0147
Toxoplasma gondii patched family protein 0.0022 0.0013 0.0032
Loa Loa (eye worm) beta-lactamase 0.0039 0.0053 0.0095
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0049 0.0078 0.0193
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.1164 0.2752 0.679
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0004 0.0077
Echinococcus granulosus tubulin alpha chain 0.0064 0.0113 0.0147
Loa Loa (eye worm) chloride channel protein 7 0.0101 0.0203 0.0368
Loa Loa (eye worm) hypothetical protein 0.0126 0.0263 0.0476
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Loa Loa (eye worm) hypothetical protein 0.0182 0.0396 0.0716
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0109 0.0221 0.0545
Schistosoma mansoni 6-phosphofructokinase 0.0109 0.0223 0.0404
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0053 0.0096
Leishmania major beta tubulin 0.0054 0.009 0.0222
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0016
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0247 0.0552 0.1363
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0017 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0022
Leishmania major epsilon tubulin, putative 0.0039 0.0053 0.0132
Echinococcus granulosus Tubulin beta 2C chain 0.0054 0.009 0.0117
Trichomonas vaginalis tubulin alpha chain, putative 0.0022 0.0013 0.0227
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.0027 0.0036
Brugia malayi hypothetical protein 0.0022 0.0013 0.0024
Plasmodium vivax endoplasmin, putative 0.0025 0.002 0.0053
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0039 0.0039
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0132 0.0277 0.4849
Echinococcus multilocularis allatostatin A receptor 0.2316 0.5513 0.5513
Entamoeba histolytica endo-1,4-beta-xylanase, putative 0.0039 0.0055 0.0656
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Echinococcus granulosus tubulin gamma 1 chain 0.0039 0.0053 0.0069
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0107 0.0264
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0021 0.0053
Plasmodium vivax tubulin beta chain, putative 0.0054 0.009 0.0237
Trichomonas vaginalis esterase, putative 0.0039 0.0053 0.0929
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.006 0.0105 0.0136
Mycobacterium tuberculosis Probable dihydroorotate dehydrogenase PyrD 0.0143 0.0303 0.0748
Plasmodium falciparum glutathione reductase 0.0048 0.0075 0.0196
Leishmania major carbonic anhydrase-like protein 0.1164 0.2752 0.679
Leishmania major CBS domain protein, conserved 0.0101 0.0203 0.0502
Echinococcus granulosus neuropeptide Y receptor 0.2316 0.5513 0.7173
Mycobacterium ulcerans hypothetical protein 0.0039 0.0055 0.0135
Plasmodium vivax tubulin alpha chain, putative 0.0064 0.0113 0.0296
Trichomonas vaginalis tubulin epsilon chain, putative 0.0064 0.0113 0.1975
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Schistosoma mansoni lipoxygenase 0.1365 0.3234 0.5865
Echinococcus multilocularis tubulin alpha 0.0039 0.0053 0.0053
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0031 0.0077
Trichomonas vaginalis heat shock protein, putative 0.002 0.0008 0.0143
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0022
Loa Loa (eye worm) latrophilin receptor protein 2 0.0036 0.0047 0.0083
Brugia malayi Patched family protein 0.0022 0.0013 0.0024
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0132 0.0277 0.4849
Brugia malayi CBS domain containing protein 0.0101 0.0203 0.0369
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0022
Echinococcus multilocularis S formylglutathione hydrolase 0.0039 0.0055 0.0055
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0049 0.012
Schistosoma mansoni chloride channel protein 0.0101 0.0203 0.0369
Leishmania major acetyl-CoA synthetase, putative 0.0037 0.0049 0.012
Echinococcus granulosus para nitrobenzyl esterase 0.0101 0.0202 0.0263
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.002 0.0009 0.0454
Leishmania major beta tubulin 0.0054 0.009 0.0222
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0107 0.0193
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0125 0.0261 0.0643
Schistosoma mansoni hypothetical protein 0.2316 0.5513 1
Trypanosoma cruzi AMP-activated protein kinase, gamma regulatory subunit 0.0101 0.0203 0.0502
Loa Loa (eye worm) hypothetical protein 0.0094 0.0185 0.0334
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0132 0.0277 0.3336
Schistosoma mansoni neuropeptide receptor 0.2316 0.5513 1
Echinococcus granulosus biogenic amine 5HT receptor 0.2316 0.5513 0.7173
Loa Loa (eye worm) tubulin alpha 2 0.0047 0.0073 0.013
Schistosoma mansoni rhodopsin-like orphan GPCR 0.2316 0.5513 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0053 0.0095
Loa Loa (eye worm) hypothetical protein 0.0111 0.0227 0.041
Leishmania major beta tubulin 0.0054 0.009 0.0222
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0125 0.0261 0.0643
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0036 0.0047 0.0085
Brugia malayi Patched family protein 0.0022 0.0013 0.0024
Brugia malayi chloride channel protein 7 0.0101 0.0203 0.0369
Schistosoma mansoni dihydroorotate dehydrogenase 0.0143 0.0303 0.055
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0049 0.0078 0.0078
Brugia malayi MH2 domain containing protein 0.0406 0.0933 0.1693
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0107 0.0139
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.0027 0.0027
Loa Loa (eye worm) neuropeptide F receptor 0.2316 0.5513 1
Trichomonas vaginalis ap endonuclease, putative 0.0053 0.0087 0.1515
Trichomonas vaginalis chromobox protein, putative 0.007 0.0129 0.225
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0034 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0027 0.0476
Schistosoma mansoni rhodopsin-like orphan GPCR 0.2316 0.5513 1
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0083 0.146
Echinococcus multilocularis tubulin subunit beta 0.0054 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0094 0.0185 0.0334
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0037 0.0049 0.012
Loa Loa (eye worm) patched family protein 0.0022 0.0013 0.0022
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0037 0.0049 0.012
Schistosoma mansoni hypothetical protein 0.0036 0.0047 0.0085
Schistosoma mansoni hypothetical protein 0.0078 0.0147 0.0266
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0051 0.0083 0.0206
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0109 0.0223 1
Schistosoma mansoni amine GPCR 0.2316 0.5513 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0004 0.0077
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0022
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0037 0.0049 0.012
Schistosoma mansoni tubulin subunit alpha 0.0064 0.0113 0.0205
Brugia malayi Myosin head containing protein 0.0022 0.0013 0.0024
Brugia malayi chromobox protein homolog 3 0.0039 0.0055 0.0099
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0017 0.0002 0.0003
Schistosoma mansoni smad1 5 8 and 0.0028 0.0027 0.0049
Schistosoma mansoni opsin-like receptor 0.2316 0.5513 1
Echinococcus granulosus dnaJ subfamily B 0.0431 0.0994 0.1293
Onchocerca volvulus 0.2316 0.5513 1
Echinococcus granulosus endoplasmin 0.002 0.0008 0.0011
Brugia malayi hypothetical protein 0.0022 0.0013 0.0024
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0017 0.0002 0.0003
Echinococcus multilocularis snurportin 1 0.0219 0.0487 0.0487
Echinococcus granulosus neuropeptide FF receptor 2 0.2316 0.5513 0.7173
Leishmania major chloride channel protein, putative 0.0101 0.0203 0.0502
Loa Loa (eye worm) carbonic anhydrase 3 0.1164 0.2752 0.499
Loa Loa (eye worm) hypothetical protein 0.0101 0.0203 0.0368
Trichomonas vaginalis tubulin, putative 0.0022 0.0013 0.0227
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0053 0.0087 0.0214
Echinococcus granulosus g protein coupled receptor 0.2316 0.5513 0.7173
Echinococcus multilocularis rhodopsin orphan GPCR 0.2316 0.5513 0.5513
Loa Loa (eye worm) esterase D 0.0039 0.0055 0.0098
Trypanosoma cruzi chloride channel protein, putative 0.0101 0.0203 0.0502
Loa Loa (eye worm) carboxylesterase 0.0596 0.139 0.2521
Schistosoma mansoni alpha-1 adrenergic receptor 0.2316 0.5513 1
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0037 0.0049 0.012
Echinococcus multilocularis thyroid hormone receptor alpha 0.0017 0.0002 0.0002
Schistosoma mansoni tubulin subunit beta 0.0054 0.009 0.0163
Brugia malayi Low molecular weight phosphotyrosine protein phosphatase containing protein 0.0132 0.0277 0.0503
Brugia malayi Patched family protein 0.0022 0.0013 0.0024
Leishmania major heat shock protein 83-1 0.0025 0.002 0.005
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Trypanosoma cruzi alpha tubulin, putative 0.0064 0.0113 0.0279
Echinococcus multilocularis tachykinin peptides receptor 99D 0.2316 0.5513 0.5513
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0039 0.007
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0064 0.0113 0.1975
Loa Loa (eye worm) patched family protein 0.0022 0.0013 0.0022
Loa Loa (eye worm) tubulin beta chain 0.0054 0.009 0.0162
Brugia malayi follicle stimulating hormone receptor 0.2316 0.5513 1
Schistosoma mansoni amine GPCR 0.2316 0.5513 1
Echinococcus granulosus 6 phosphofructokinase 0.0109 0.0223 0.029
Leishmania major alpha tubulin 0.0064 0.0113 0.0279
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0039 0.007
Trichomonas vaginalis tubulin, putative 0.0017 0.0001 0.0014
Schistosoma mansoni lozenge 0.0039 0.0055 0.0099
Echinococcus granulosus neuropeptide receptor 0.2316 0.5513 0.7173
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0031 0.0548
Leishmania major heat shock protein 83-1 0.0025 0.002 0.005
Mycobacterium leprae PROBABLE INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE GUAB1(IMP DEHYDROGENASE) (IMPDH) (IMPD) 0.0811 0.1904 0.4697
Echinococcus multilocularis neutral alpha glucosidase AB 0.0058 0.01 0.01
Trichomonas vaginalis alpha-glucosidase, putative 0.0058 0.01 0.1755
Trichomonas vaginalis sucrase-isomaltase, putative 0.0058 0.01 0.1755
Brugia malayi hypothetical protein 0.0313 0.071 0.1288
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0109 0.0223 0.055
Onchocerca volvulus 0.2316 0.5513 1
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.2316 0.5513 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0125 0.0261 0.3138
Brugia malayi Tubulin alpha chain 0.0064 0.0113 0.0205
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0101 0.0203 0.0369
Brugia malayi beta-lactamase family protein 0.0039 0.0053 0.0096
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Leishmania major glycosyl hydrolase-like protein 0.0022 0.0013 0.0031
Echinococcus granulosus heat shock protein 90 0.002 0.0008 0.0011
Schistosoma mansoni biogenic amine receptor 0.2316 0.5513 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0025 0.0044
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0109 0.0221 0.0545
Brugia malayi alpha-tubulin 0.0064 0.0113 0.0205
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0121 0.025 0.0616
Toxoplasma gondii hypothetical protein 0.0022 0.0013 0.0032
Trypanosoma cruzi GMP reductase 0.1707 0.4053 1
Schistosoma mansoni aryl hydrocarbon receptor 0.017 0.0369 0.0669
Schistosoma mansoni steroid hormone receptor ad4bp 0.0017 0.0002 0.0003
Echinococcus granulosus g protein coupled receptor 0.2316 0.5513 0.7173
Echinococcus granulosus S formylglutathione hydrolase 0.0039 0.0055 0.0071
Brugia malayi AMP-binding enzyme family protein 0.0125 0.0261 0.0473
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0058 0.0143
Echinococcus granulosus lamin dm0 0.0058 0.0099 0.0129
Mycobacterium tuberculosis Probable oxidoreductase 0.0121 0.025 0.0616
Loa Loa (eye worm) alpha-tubulin 0.0064 0.0113 0.0203
Onchocerca volvulus 0.0308 0.0699 0.1265
Echinococcus granulosus thyrotropin releasing hormone receptor 0.2316 0.5513 0.7173
Brugia malayi hypothetical protein 0.2316 0.5513 1
Echinococcus granulosus Tubulin alpha 1 chain 0.0064 0.0113 0.0147
Echinococcus granulosus TGF beta signal transducer SmadC 0.0028 0.0027 0.0035
Echinococcus multilocularis GPCR, family 2 0.0036 0.0047 0.0047
Mycobacterium ulcerans cell division protein FtsZ 0.0017 0.0001 0.0002
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0053 0.0131
Plasmodium vivax glutathione reductase, putative 0.0048 0.0075 0.0196
Echinococcus multilocularis g-protein coupled receptor 0.2316 0.5513 0.5513
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.0101 0.0203 0.0502
Onchocerca volvulus 0.0022 0.0013 0.0021
Entamoeba histolytica tubulin alpha chain, putative 0.0064 0.0113 0.1356
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0022
Trichomonas vaginalis alpha-glucosidase, putative 0.0058 0.01 0.1755
Trypanosoma brucei alpha tubulin 0.0064 0.0113 0.0279
Mycobacterium tuberculosis Conserved protein 0.0039 0.0053 0.0131
Trypanosoma cruzi dihydroorotate dehydrogenase (fumarate), putative 0.0143 0.0303 0.0748
Echinococcus granulosus chromobox protein 1 0.007 0.0129 0.0167
Brugia malayi hypothetical protein 0.0239 0.0533 0.0967
Schistosoma mansoni rhodopsin-like orphan GPCR 0.2316 0.5513 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0049 0.012
Brugia malayi Glycosyl hydrolases family 31 protein 0.0058 0.01 0.0182
Schistosoma mansoni rhodopsin-like orphan GPCR 0.2316 0.5513 1
Brugia malayi Pre-SET motif family protein 0.0033 0.0039 0.007
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0017 0.0001 0.0002
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0053 0.0096
Echinococcus multilocularis tubulin alpha 1C chain 0.0064 0.0113 0.0113
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0031 0.1539
Brugia malayi hypothetical protein 0.2316 0.5513 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.2316 0.5513 1
Leishmania major heat shock protein 83-1 0.0025 0.002 0.005
Echinococcus multilocularis G protein coupled receptor 139 0.2316 0.5513 0.5513
Mycobacterium tuberculosis Carboxylesterase LipT 0.0101 0.0202 0.0499
Echinococcus multilocularis muscleblind protein 0.0126 0.0263 0.0263
Schistosoma mansoni smad1 5 8 and 0.0028 0.0027 0.0049
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0125 0.0261 0.0641
Brugia malayi Voltage gated chloride channel family protein 0.0101 0.0203 0.0369
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0002 0.0003
Brugia malayi Carboxylesterase family protein 0.0101 0.0202 0.0367
Leishmania major alpha tubulin 0.0064 0.0113 0.0279
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Toxoplasma gondii HEAT repeat-containing protein 0.0021 0.001 0.0024
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0083 0.0206
Leishmania major 4-coumarate:coa ligase-like protein 0.0125 0.0261 0.0643
Brugia malayi phosphofructokinase 0.0109 0.0223 0.0404
Schistosoma mansoni rhodopsin-like orphan GPCR 0.2316 0.5513 1
Echinococcus granulosus g-protein coupled receptor 0.2316 0.5513 0.7173
Schistosoma mansoni heat shock protein 0.0025 0.002 0.0037
Loa Loa (eye worm) hypothetical protein 0.0596 0.139 0.2521
Brugia malayi Muscleblind-like protein 0.0126 0.0263 0.0477
Trichomonas vaginalis tubulin beta chain, putative 0.0064 0.0113 0.1975
Trichomonas vaginalis tubulin beta chain, putative 0.0064 0.0113 0.1975
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Mycobacterium ulcerans transcriptional regulator 0.0101 0.0203 0.0502
Echinococcus granulosus neuropeptide receptor 0.2316 0.5513 0.7173
Brugia malayi RNA, U transporter 1 0.0058 0.0101 0.0183
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0002
Brugia malayi hypothetical protein 0.2316 0.5513 1
Schistosoma mansoni jumonji domain containing protein 0.0059 0.0102 0.0186
Trypanosoma brucei importin beta-1 subunit, putative 0.0021 0.001 0.0024
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0107 0.0194
Trichomonas vaginalis tubulin epsilon chain, putative 0.0064 0.0113 0.1975
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0017 0.0001 0.0002
Leishmania major alpha tubulin 0.0064 0.0113 0.0279
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0204 0.0449 0.0815
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0101 0.0248
Echinococcus multilocularis geminin 0.0948 0.2232 0.2232
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0017 0.0002 0.0002
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0037 0.0049 0.012
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0037 0.0049 0.012
Echinococcus multilocularis isocitrate dehydrogenase 0.0049 0.0078 0.0078
Loa Loa (eye worm) oxidoreductase 0.0037 0.0049 0.0087
Brugia malayi heat shock protein 90 0.0025 0.002 0.0037
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0107 0.0264
Toxoplasma gondii isocitrate dehydrogenase 0.0049 0.0078 0.0193
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.2316 0.5513 0.7173
Brugia malayi Doublecortin family protein 0.0239 0.0533 0.0967
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0017 0.0002 0.0003
Leishmania major beta tubulin 0.0054 0.009 0.0222
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0107 0.0192
Loa Loa (eye worm) patched family protein 0.0022 0.0013 0.0022
Echinococcus multilocularis SNF4:AMP activated protein kinase gamma subunit 0.0101 0.0203 0.0203
Schistosoma mansoni hypothetical protein 0.015 0.032 0.058
Treponema pallidum Mg2+ transport protein (mgtE) 0.0101 0.0203 0.9135
Loa Loa (eye worm) isocitrate dehydrogenase 0.0049 0.0078 0.0141
Leishmania major hypothetical protein, conserved 0.0041 0.0058 0.0143
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Echinococcus multilocularis fmrfamide receptor 0.2316 0.5513 0.5513
Echinococcus multilocularis importin subunit beta 1 0.0021 0.001 0.001
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0053 0.0131
Echinococcus multilocularis sex peptide receptor 0.2316 0.5513 0.5513
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0101 0.0202 0.0263
Brugia malayi Patched related family protein 4 0.0022 0.0013 0.0024
Giardia lamblia Beta tubulin 0.0054 0.009 0.1641
Plasmodium falciparum heat shock protein 90 0.0025 0.002 0.0053
Giardia lamblia Alpha-tubulin 0.0064 0.0113 0.2056
Loa Loa (eye worm) phosphotyrosine protein phosphatase 0.0132 0.0277 0.0501
Brugia malayi 6-phosphofructokinase 0.0109 0.0223 0.0404
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0017 0.0002 0.0003
Trypanosoma brucei importin beta-1 subunit, putative 0.0021 0.001 0.0024
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Echinococcus multilocularis neuropeptide Y receptor 0.2316 0.5513 0.5513
Trypanosoma brucei beta tubulin 0.0054 0.009 0.0222
Echinococcus multilocularis carbonic anhydrase 0.0547 0.1272 0.1272
Onchocerca volvulus 0.0101 0.0202 0.0363
Echinococcus granulosus intermediate filament protein 0.0058 0.0099 0.0129
Trichomonas vaginalis tubulin gamma chain, putative 0.0017 0.0001 0.0014
Brugia malayi cytoplasmic intermediate filament protein 0.0031 0.0035 0.0063
Brugia malayi G protein-coupled receptor F59B2.13 0.2316 0.5513 1
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.0223 0.2681
Mycobacterium leprae conserved hypothetical protein 0.0101 0.0203 0.05
Onchocerca volvulus Protein patched homolog 0.0022 0.0013 0.0021
Schistosoma mansoni endoplasmin 0.0025 0.002 0.0037
Plasmodium falciparum protein MAM3, putative 0.0101 0.0203 0.0534
Echinococcus multilocularis mothers against decapentaplegic 5 0.0028 0.0027 0.0027
Chlamydia trachomatis Mg++ transporter 0.0101 0.0203 1
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.2316 0.5513 0.5513
Brugia malayi Carboxylesterase family protein 0.0101 0.0202 0.0367
Echinococcus multilocularis mitogen activated protein kinase 0.0051 0.0083 0.0083
Mycobacterium ulcerans secreted Mpt51/Mpb51 antigen protein FbpD 0.0039 0.0055 0.0135
Brugia malayi Patched family protein 0.0022 0.0013 0.0024
Echinococcus granulosus tubulin alpha chain 0.0064 0.0113 0.0147
Echinococcus granulosus neuropeptide s receptor 0.2316 0.5513 0.7173
Loa Loa (eye worm) hypothetical protein 0.0363 0.083 0.1504
Mycobacterium tuberculosis Probable conserved transmembrane alanine and leucine rich protein 0.0101 0.0203 0.0502
Brugia malayi Tubulin beta chain 0.0017 0.0001 0.0001
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0004 0.0077
Onchocerca volvulus 0.0152 0.0325 0.0586
Trichomonas vaginalis tubulin beta chain, putative 0.0064 0.0113 0.1975
Trypanosoma brucei heat shock protein, putative 0.0025 0.002 0.005
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0056 0.0094 0.165
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA 0.0132 0.0277 0.0684
Loa Loa (eye worm) hypothetical protein 0.0191 0.0417 0.0756
Echinococcus granulosus carbonic anhydrase 0.0547 0.1272 0.1654
Brugia malayi inosine-5'-monophosphate dehydrogenase 0.0709 0.1661 0.3013
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.0056 0.0094 0.0233
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0094 0.0185 0.9081
Brugia malayi AMP-binding enzyme family protein 0.0125 0.0261 0.0473
Echinococcus multilocularis aryl hydrocarbon receptor 0.0127 0.0264 0.0264
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0547 0.1272 0.2307
Brugia malayi ancient conserved domain protein 4 0.0101 0.0203 0.0369
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0022
Trypanosoma cruzi chloride channel protein, putative 0.0101 0.0203 0.0502
Leishmania major inosine-5-monophosphate dehydrogenase 0.1707 0.4053 1
Brugia malayi MH2 domain containing protein 0.0028 0.0027 0.0049
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.0811 0.1904 0.4698
Wolbachia endosymbiont of Brugia malayi IMP dehydrogenase 0.1707 0.4053 1
Echinococcus multilocularis H(+):Cl() exchange transporter 4 0.0101 0.0203 0.0203
Onchocerca volvulus 0.0022 0.0013 0.002
Loa Loa (eye worm) hypothetical protein 0.0047 0.0073 0.013
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0053 0.0087 0.0156
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.0143 0.0303 0.0748
Echinococcus granulosus expressed conserved protein 0.0341 0.0777 0.1011
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0002
Plasmodium vivax tubulin gamma chain, putative 0.0039 0.0053 0.014
Leishmania major beta tubulin 0.0054 0.009 0.0222
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0053 0.0087 0.1039
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0027 0.0025 0.0044
Loa Loa (eye worm) hypothetical protein 0.0058 0.0099 0.0178
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0022
Echinococcus multilocularis hypothetical protein 0.0064 0.0113 0.0113
Trichomonas vaginalis antibiotic synthetase, putative 0.0037 0.0049 0.0851
Trypanosoma brucei alpha tubulin 0.0064 0.0113 0.0279
Loa Loa (eye worm) hypothetical protein 0.0101 0.0203 0.0368
Giardia lamblia Beta tubulin 0.0054 0.009 0.1641
Brugia malayi Patched family protein 0.0022 0.0013 0.0024
Leishmania major ATP-dependent phosphofructokinase 0.0109 0.0223 0.055
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0022
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0101 0.0203 0.0369
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0049 0.012
Leishmania major beta tubulin 0.0054 0.009 0.0222
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0107 0.0264
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Mycobacterium ulcerans hypothetical protein 0.0039 0.0055 0.0135
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0033 0.0039 0.0039
Brugia malayi hypothetical protein 0.0022 0.0013 0.0024
Plasmodium falciparum tubulin beta chain 0.0054 0.009 0.0237
Plasmodium vivax delta tubulin, putative 0.0017 0.0001 0.0002
Mycobacterium ulcerans acyl-CoA synthetase 0.0125 0.0261 0.0643
Brugia malayi hypothetical protein 0.0122 0.0254 0.0461
Onchocerca volvulus 0.0022 0.0013 0.0021
Loa Loa (eye worm) hypothetical protein 0.0156 0.0333 0.0604
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0075 0.0196
Echinococcus granulosus Tubulin beta 2C chain 0.0054 0.009 0.0117
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.007 0.0128 0.1537
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0004 0.0077
Brugia malayi AMP-binding enzyme family protein 0.0037 0.0049 0.0088
Toxoplasma gondii hypothetical protein 0.0547 0.1272 0.3138
Brugia malayi Niemann-Pick C1 protein precursor 0.0363 0.083 0.1505
Brugia malayi CXXC zinc finger family protein 0.003 0.0033 0.006
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0058 0.01 0.1755
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0031 0.0548
Loa Loa (eye worm) BEN-1 protein 0.0054 0.009 0.0162
Onchocerca volvulus 0.0239 0.0533 0.0964
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.006 0.0105 0.1258
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0033 0.0039 0.007
Onchocerca volvulus 0.2316 0.5513 1
Echinococcus granulosus rhodopsin orphan GPCR 0.2316 0.5513 0.7173
Echinococcus granulosus ecdysone induced protein 78C 0.0017 0.0002 0.0002
Echinococcus multilocularis protein patched 0.0156 0.0333 0.0333
Schistosoma mansoni histamine h1 receptor 0.2316 0.5513 1
Trypanosoma cruzi heat shock protein 90, putative 0.002 0.0008 0.002
Echinococcus granulosus orexin receptor type 2 0.2316 0.5513 0.7173
Schistosoma mansoni rhodopsin-like orphan GPCR 0.2316 0.5513 1
Trypanosoma cruzi Domain of unknown function DUF21, putative 0.0101 0.0203 0.0502
Echinococcus granulosus carbonic anhydrase 0.0547 0.1272 0.1654
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.006 0.0105 0.1833
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.002 0.0008 0.002
Echinococcus multilocularis tubulin alpha 3 chain 0.0064 0.0113 0.0113
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0053 0.0095
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0037 0.0049 0.0118
Plasmodium falciparum alpha tubulin 1 0.0064 0.0113 0.0296
Echinococcus multilocularis cpg binding protein 0.0032 0.0037 0.0037
Trypanosoma cruzi hypothetical protein, conserved 0.0058 0.01 0.0247
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0049 0.012
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase 0.0132 0.0277 0.5048
Brugia malayi Tubulin beta chain 0.0022 0.0013 0.0024
Mycobacterium tuberculosis Probable conserved exported protein 0.0039 0.0055 0.0135
Brugia malayi Tubulin alpha-2 chain 0.0064 0.0113 0.0205
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0028 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Echinococcus granulosus rhodopsin orphan GPCR 0.2316 0.5513 0.7173
Toxoplasma gondii dihydroorotate dehydrogenase reveal, putative 0.0143 0.0303 0.0748
Schistosoma mansoni cpg binding protein 0.0032 0.0037 0.0067
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0017 0.0002 0.0003
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0058 0.0099 0.0178
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0109 0.0223 0.0548
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0051 0.0083 0.0206
Loa Loa (eye worm) G-protein coupled receptor 0.2316 0.5513 1
Echinococcus granulosus heat shock protein 90 0.0025 0.002 0.0026
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0125 0.0261 0.0643
Echinococcus multilocularis Polycystic kidney disease protein 0.0239 0.0533 0.0533
Loa Loa (eye worm) hypothetical protein 0.0313 0.071 0.1287
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.2316 0.5513 0.5513
Echinococcus granulosus tubulin delta chain 0.0017 0.0001 0.0001
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.1707 0.4053 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0053 0.0087 0.0214
Loa Loa (eye worm) hypothetical protein 0.0182 0.0396 0.0716
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0107 0.0264
Loa Loa (eye worm) tubulin beta-2A chain 0.0054 0.009 0.0162
Toxoplasma gondii patched family protein 0.0022 0.0013 0.0032
Echinococcus multilocularis neuropeptides capa receptor 0.2316 0.5513 0.5513
Trichomonas vaginalis tubulin beta chain, putative 0.0054 0.009 0.1577
Trypanosoma brucei epsilon tubulin 0.0039 0.0053 0.0132
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0049 0.012
Trypanosoma cruzi heat shock protein 85, putative 0.0025 0.002 0.005
Brugia malayi Tachykinin-like peptides receptor 99D 0.2316 0.5513 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0017 0.0002 0.0002
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0094 0.0185 0.0456
Toxoplasma gondii CBS domain-containing protein 0.0101 0.0203 0.0502
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0125 0.0261 0.0643
Echinococcus granulosus mothers against decapentaplegic 5 0.0028 0.0027 0.0035
Trypanosoma brucei beta tubulin 0.0039 0.0053 0.0132
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Loa Loa (eye worm) carboxylesterase 0.0101 0.0202 0.0365
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0053 0.0131
Schistosoma mansoni RAR-like nuclear receptor 0.0017 0.0002 0.0003
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0031 0.0077
Trypanosoma brucei GMP reductase 0.1707 0.4053 1
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Leishmania major alpha tubulin 0.0064 0.0113 0.0279
Schistosoma mansoni rab6-interacting 0.0239 0.0533 0.0967
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0022 0.0013 0.022
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0022
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0022 0.0013 0.0146
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.2316 0.5513 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0039 0.0051
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0031 0.0035 0.0062
Loa Loa (eye worm) hypothetical protein 0.0101 0.0202 0.0365
Loa Loa (eye worm) hypothetical protein 0.0094 0.0185 0.0334
Loa Loa (eye worm) hypothetical protein 0.0057 0.0097 0.0174
Leishmania major beta tubulin 0.0054 0.009 0.0222
Echinococcus granulosus tm gpcr rhodopsin 0.3222 0.7686 1
Plasmodium falciparum lipid/sterol:H+ symporter 0.0022 0.0013 0.0035
Entamoeba histolytica tubulin family protein 0.0054 0.009 0.1081
Echinococcus multilocularis serotonin receptor 0.2316 0.5513 0.5513
Mycobacterium ulcerans hypothetical protein 0.0039 0.0055 0.0135
Trypanosoma cruzi beta tubulin, putative 0.0054 0.009 0.0222
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0547 0.1272 0.2307
Brugia malayi Carboxylesterase family protein 0.0101 0.0202 0.0367
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0017 0.0002 0.0002
Brugia malayi putative neuropeptide receptor 0.2316 0.5513 1
Brugia malayi hypothetical protein 0.2316 0.5513 1
Echinococcus granulosus aryl hydrocarbon receptor 0.0127 0.0264 0.0344
Trypanosoma cruzi hypothetical protein, conserved 0.0058 0.01 0.0247
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0083 0.0151
Echinococcus granulosus tachykinin peptides receptor 99D 0.2316 0.5513 0.7173
Brugia malayi latrophilin 2 splice variant baaae 0.0078 0.0147 0.0266
Trypanosoma cruzi GMP reductase 0.1707 0.4053 1
Trypanosoma brucei protein kinase, putative 0.0051 0.0083 0.0206
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0088 0.0173 0.0426
Echinococcus granulosus g protein coupled receptor 0.2316 0.5513 0.7173
Echinococcus granulosus alpha 1A adrenergic receptor 0.2316 0.5513 0.7173
Brugia malayi Pre-SET motif family protein 0.0224 0.0497 0.0902
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.2316 0.5513 0.5513
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0017 0.0002 0.0002
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.2316 0.5513 0.5513
Trypanosoma brucei heat shock protein, putative 0.0025 0.002 0.005
Schistosoma mansoni ap endonuclease 0.0053 0.0087 0.0157
Trichomonas vaginalis importin beta-1, putative 0.0017 0 0.0008
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.2316 0.5513 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.2316 0.5513 0.7173
Leishmania major gamma-tubulin 0.0039 0.0053 0.0132
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.2316 0.5513 1
Echinococcus multilocularis tubulin delta chain 0.0017 0.0001 0.0001
Echinococcus granulosus 7TM GPCR rhodopsin 0.2316 0.5513 0.7173
Schistosoma mansoni neuropeptide F-like receptor 0.2316 0.5513 1
Onchocerca volvulus 0.0101 0.0203 0.0366
Schistosoma mansoni rhodopsin-like orphan GPCR 0.2316 0.5513 1
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.1707 0.4053 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0058 0.01 0.1755
Entamoeba histolytica hypothetical protein 0.007 0.0128 0.1537
Toxoplasma gondii thioredoxin reductase 0.0048 0.0075 0.0184
Echinococcus granulosus GPCR family 2 0.0036 0.0047 0.0061
Echinococcus multilocularis inosine 5' monophosphate dehydrogenase 2 0.1707 0.4053 0.4053
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0053 0.0087 0.0227
Echinococcus granulosus peroxisome assembly protein 26 0.0064 0.0113 0.0147
Brugia malayi inosine-5'-monophosphate dehydrogenase family protein 0.1707 0.4053 0.7351
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.0223 0.3898
Echinococcus multilocularis Niemann Pick C1 protein 0.0518 0.1203 0.1203
Schistosoma mansoni hypothetical protein 0.0948 0.2232 0.4049
Schistosoma mansoni biogenic amine receptor 0.2316 0.5513 1
Loa Loa (eye worm) hypothetical protein 0.0547 0.1272 0.2305
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0031 0.0372
Schistosoma mansoni tubulin subunit beta 0.0054 0.009 0.0163
Mycobacterium tuberculosis Conserved protein 0.0101 0.0203 0.0502
Schistosoma mansoni rab6-interacting 0.0239 0.0533 0.0967
Echinococcus multilocularis Tubulin alpha 1 chain 0.0064 0.0113 0.0113
Schistosoma mansoni acetyl-CoA synthetase 0.0037 0.0049 0.0088
Onchocerca volvulus 0.0239 0.0533 0.0964
Echinococcus multilocularis 6 phosphofructokinase 0.0109 0.0223 0.0223
Giardia lamblia Hypothetical protein 0.0101 0.0203 0.3707
Brugia malayi Dopamine receptor 0.2316 0.5513 1
Mycobacterium tuberculosis Conserved protein 0.0101 0.0203 0.0502
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0156 0.0333 0.0604
Schistosoma mansoni importin beta-1 0.0021 0.001 0.0018
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0018 0.0002 0.0002
Echinococcus granulosus BC026374 protein S09 family 0.0101 0.0202 0.0263
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0101 0.0203 0.0369
Schistosoma mansoni neuropeptide receptor 0.2316 0.5513 1
Echinococcus multilocularis dnaJ subfamily B 0.0431 0.0994 0.0994
Echinococcus granulosus carbonic anhydrase II 0.1164 0.2752 0.358
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0021 0.0053
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.2316 0.5513 1
Mycobacterium ulcerans hypothetical protein 0.0039 0.0055 0.0135
Onchocerca volvulus 0.0022 0.0013 0.0021
Entamoeba histolytica acyl-CoA synthetase, putative 0.0125 0.0261 0.3138
Trypanosoma cruzi heat shock protein 85, putative 0.002 0.0008 0.002
Brugia malayi Patched related family protein 10 0.0022 0.0013 0.0024
Trichomonas vaginalis tubulin, putative 0.0022 0.0013 0.0227
Trypanosoma cruzi tubulin gamma chain 0.0039 0.0053 0.0132
Loa Loa (eye worm) hypothetical protein 0.0039 0.0053 0.0095
Plasmodium falciparum alpha tubulin 2 0.0064 0.0113 0.0296
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.2316 0.5513 1
Loa Loa (eye worm) hypothetical protein 0.0239 0.0533 0.0965
Loa Loa (eye worm) chloride channel 3 0.0101 0.0203 0.0368
Schistosoma mansoni ap endonuclease 0.0053 0.0087 0.0157
Schistosoma mansoni gliotactin 0.0101 0.0202 0.0367
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Onchocerca volvulus 0.2316 0.5513 1
Schistosoma mansoni carbonic anhydrase-related 0.0547 0.1272 0.2307
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0037 0.0049 0.0128
Echinococcus multilocularis rhodopsin orphan GPCR 0.2316 0.5513 0.5513
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0033 0.0039 0.007
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0547 0.1272 0.2307
Leishmania major beta tubulin 0.0054 0.009 0.0222
Mycobacterium ulcerans hypothetical protein 0.0101 0.0203 0.0502
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0107 0.0264
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0017 0.0002 0.0003
Plasmodium falciparum tubulin delta chain, putative 0.0017 0.0001 0.0002
Echinococcus multilocularis ecdysone induced protein 78C 0.0017 0.0002 0.0002
Brugia malayi hypothetical protein 0.2316 0.5513 1
Toxoplasma gondii alpha-tubulin I, putative 0.0064 0.0113 0.0279
Brugia malayi Calcitonin receptor-like protein seb-1 0.0114 0.0233 0.0422
Onchocerca volvulus 0.003 0.0033 0.0057
Echinococcus multilocularis neuropeptide receptor A26 0.2316 0.5513 0.5513
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0017 0.0002 0.0002
Onchocerca volvulus 0.0132 0.0277 0.0499
Leishmania major beta tubulin 0.0054 0.009 0.0222
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.002 0.0008 0.002
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0037 0.0049 0.012
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.006 0.0105 0.1833
Trypanosoma brucei tubulin delta chain 0.0017 0.0001 0.0002
Echinococcus granulosus dro:myosuppressin receptor 0.2316 0.5513 0.7173
Toxoplasma gondii heat shock protein HSP90 0.0025 0.002 0.005
Echinococcus multilocularis Tubulin beta 2C chain 0.0054 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0126 0.0263 0.0476
Plasmodium vivax SET domain protein, putative 0.0033 0.0039 0.0102
Loa Loa (eye worm) hypothetical protein 0.0039 0.0053 0.0095
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.1164 0.2752 0.4991
Brugia malayi Latrophilin receptor protein 2 0.0036 0.0047 0.0085
Trichomonas vaginalis phosphofructokinase, putative 0.0109 0.0223 0.3898
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0037 0.0049 0.0088
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Trypanosoma brucei zeta tubulin 0.0017 0.0001 0.0002
Schistosoma mansoni Smad4 0.0028 0.0027 0.0049
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Loa Loa (eye worm) hypothetical protein 0.0313 0.071 0.1287
Trichomonas vaginalis alpha-glucosidase, putative 0.0058 0.01 0.1755
Echinococcus multilocularis neuropeptide FF receptor 2 0.2316 0.5513 0.5513
Brugia malayi isocitrate dehydrogenase 0.0049 0.0078 0.0142
Trypanosoma cruzi zeta tubulin, putative 0.0017 0.0001 0.0002
Leishmania major beta tubulin 0.0054 0.009 0.0222
Brugia malayi hypothetical protein 0.1 0.2357 0.4276
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0121 0.025 0.0614
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0039 0.007
Onchocerca volvulus 0.0044 0.0066 0.0117
Echinococcus multilocularis tumor protein p63 0.034 0.0776 0.0776
Trypanosoma brucei inosine-5'-monophosphate dehydrogenase 0.1707 0.4053 1
Leishmania major zeta tubulin, putative 0.0017 0.0001 0.0002
Brugia malayi hypothetical protein 0.0025 0.0021 0.0039
Trypanosoma cruzi epsilon tubulin, putative 0.0039 0.0053 0.0132
Echinococcus granulosus beta tubulin 0.0054 0.009 0.0117
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0022
Mycobacterium leprae Probable dihydroorotate dehydrogenase PyrD 0.0143 0.0303 0.0746
Entamoeba histolytica phosphofructokinase, putative 0.0109 0.0223 0.2681
Echinococcus granulosus Tubulin beta 2C chain 0.0054 0.009 0.0117
Onchocerca volvulus 0.2316 0.5513 1
Echinococcus granulosus sterol regulatory element binding protein 0.0156 0.0333 0.0434
Loa Loa (eye worm) tubulin alpha-2 chain 0.0064 0.0113 0.0203
Mycobacterium tuberculosis Probable reductase 0.0109 0.0221 0.0545
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0022
Echinococcus multilocularis tubulin alpha 1C chain 0.0064 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0132 0.0277 0.4849
Toxoplasma gondii IMP dehydrogenas 0.1707 0.4053 1
Schistosoma mansoni endoplasmin 0.0025 0.002 0.0037
Brugia malayi putative neuropeptide receptor NPR1 0.2316 0.5513 1
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0101 0.0202 0.0499
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0031 0.0571
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0033 0.0039 0.0039
Echinococcus multilocularis smad 0.0028 0.0027 0.0027
Brugia malayi Dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.0143 0.0303 0.055
Trypanosoma brucei alpha tubulin, putative 0.0022 0.0013 0.0032
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0125 0.0261 0.0641
Brugia malayi hypothetical protein 0.0022 0.0013 0.0024
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.2316 0.5513 1
Onchocerca volvulus Neuropeptide F receptor homolog 0.2316 0.5513 1
Schistosoma mansoni hypothetical protein 0.0036 0.0047 0.0085
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0049 0.0078 0.0193
Echinococcus granulosus microtubule associated protein 2 0.0664 0.1552 0.202
Schistosoma mansoni lamin 0.0058 0.0099 0.018
Trypanosoma brucei heat shock protein, putative 0.0025 0.002 0.005
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0053 0.0929
Echinococcus multilocularis microtubule associated protein 2 0.0664 0.1552 0.1552
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0055 0.0957
Brugia malayi RE15519p 0.2316 0.5513 1
Trichomonas vaginalis tubulin beta chain, putative 0.0064 0.0113 0.1975
Echinococcus multilocularis neuropeptide s receptor 0.2316 0.5513 0.5513
Echinococcus granulosus neuropeptides capa receptor 0.2316 0.5513 0.7173
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0017 0 0.0008
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0054 0.009 0.009
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0031 0.0077
Schistosoma mansoni hypothetical protein 0.015 0.032 0.058
Brugia malayi larval opioid receptor 0.2316 0.5513 1
Schistosoma mansoni hypothetical protein 0.2316 0.5513 1
Trypanosoma brucei heat shock protein 90, putative 0.0025 0.002 0.005
Mycobacterium tuberculosis Secreted antigen 85-a FbpA (mycolyl transferase 85A) (fibronectin-binding protein A) (antigen 85 complex A) 0.0039 0.0055 0.0135
Echinococcus multilocularis lamin 0.0058 0.0099 0.0099
Schistosoma mansoni biogenic amine (5HT) receptor 0.2316 0.5513 1
Leishmania major alpha tubulin 0.0064 0.0113 0.0279
Brugia malayi Dopamine receptor protein 1 0.2316 0.5513 1
Echinococcus multilocularis tubulin alpha chain 0.0064 0.0113 0.0113
Echinococcus multilocularis tubulin alpha 3 chain 0.0064 0.0113 0.0113
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0037 0.0049 0.012
Leishmania major heat shock protein 83-1 0.0025 0.002 0.005
Leishmania major dihydroorotate dehydrogenase 0.0143 0.0303 0.0748
Schistosoma mansoni single-minded 0.0059 0.0101 0.0184
Giardia lamblia Manganese-dependent inorganic pyrophosphatase, putative 0.0101 0.0203 0.3707
Loa Loa (eye worm) doublecortin family protein 0.0239 0.0533 0.0965
Brugia malayi Patched family protein 0.0022 0.0013 0.0024
Brugia malayi Patched family protein 0.0022 0.0013 0.0024
Schistosoma mansoni acetylcholinesterase 0.0101 0.0202 0.0367
Brugia malayi Patched family protein 0.0022 0.0013 0.0024
Brugia malayi Tubulin alpha-2 chain 0.0064 0.0113 0.0205
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.2316 0.5513 1
Trichomonas vaginalis heat shock protein, putative 0.0025 0.002 0.0356
Trypanosoma brucei glucosidase, putative 0.0058 0.01 0.0247
Giardia lamblia Manganese-dependent inorganic pyrophosphatase, putative 0.0101 0.0203 0.3707
Onchocerca volvulus 0.2316 0.5513 1
Echinococcus granulosus muscleblind protein 0.0126 0.0263 0.0342
Echinococcus granulosus H:Cl exchange transporter 3 0.0101 0.0203 0.0265
Loa Loa (eye worm) tubulin beta-1 chain 0.0054 0.009 0.0162
Mycobacterium tuberculosis Possible conserved membrane protein 0.0039 0.0055 0.0135
Mycobacterium ulcerans dihydroorotate dehydrogenase 2 0.0143 0.0303 0.0748
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0021 0.0056
Schistosoma mansoni lamin 0.0058 0.0099 0.018
Loa Loa (eye worm) hypothetical protein 0.0064 0.0113 0.0203
Mycobacterium ulcerans secreted antigen 85-A FbpA 0.0039 0.0055 0.0135
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0022
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0022
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0083 0.0206
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Onchocerca volvulus 0.0037 0.0049 0.0085
Trichomonas vaginalis alpha-glucosidase, putative 0.0022 0.0013 0.022
Echinococcus multilocularis lysine specific demethylase 5A 0.0059 0.0102 0.0102
Trichomonas vaginalis tubulin alpha chain, putative 0.0054 0.009 0.1577
Loa Loa (eye worm) hypothetical protein 0.0025 0.0021 0.0037
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0132 0.0277 0.3336
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0001 0.0014
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0002
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0049 0.0078 0.0102
Brugia malayi Importin beta-1 subunit 0.0021 0.001 0.0018
Brugia malayi hypothetical protein 0.2316 0.5513 1
Echinococcus multilocularis chromobox protein 1 0.007 0.0129 0.0129
Brugia malayi beta-tubulin, identical 0.0054 0.009 0.0163
Brugia malayi Patched family protein 0.0022 0.0013 0.0024
Trichomonas vaginalis tubulin alpha chain, putative 0.0022 0.0013 0.0227
Onchocerca volvulus 0.2316 0.5513 1
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0031 0.0548
Brugia malayi Isocitrate dehydrogenase 0.0049 0.0078 0.0142
Loa Loa (eye worm) hypothetical protein 0.0239 0.0533 0.0965
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0017 0.0002 0.0003
Echinococcus multilocularis serotonin receptor 0.2316 0.5513 0.5513
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0022
Trypanosoma cruzi Heat shock protein 83, putative 0.0025 0.002 0.005
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0109 0.0221 0.0545
Loa Loa (eye worm) tubulin alpha 2 0.0047 0.0073 0.013
Schistosoma mansoni hypothetical protein 0.0036 0.0047 0.0085
Trichomonas vaginalis tubulin epsilon chain, putative 0.0054 0.009 0.1577
Entamoeba histolytica acyl-coA synthetase, putative 0.0125 0.0261 0.3138
Leishmania major alpha glucosidase II subunit, putative 0.0058 0.01 0.0247
Brugia malayi protein C24B5.3 0.0022 0.0013 0.0024
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0049 0.0078 0.0142
Echinococcus granulosus lysosomal alpha glucosidase 0.0263 0.0591 0.0768
Echinococcus granulosus serotonin receptor 0.2316 0.5513 0.7173
Schistosoma mansoni alpha-glucosidase 0.0226 0.0503 0.0912
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.2316 0.5513 1
Schistosoma mansoni hypothetical protein 0.0219 0.0487 0.0883
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.2316 0.5513 0.5513
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Schistosoma mansoni opsin-like receptor 0.2316 0.5513 1
Loa Loa (eye worm) hypothetical protein 0.0596 0.139 0.2521
Loa Loa (eye worm) heat shock protein 90 0.0025 0.002 0.0036
Echinococcus multilocularis fmrfamide receptor 0.2316 0.5513 0.5513
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0017 0.0002 0.0003
Echinococcus multilocularis tubulin beta 1 chain 0.0054 0.009 0.009
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0547 0.1272 0.2307
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0114 0.0233 0.0421
Treponema pallidum cell division protein FtsZ 0.0017 0.0001 0.0035
Echinococcus granulosus lipoxygenase domain containing protein 0.0239 0.0533 0.0693
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.2316 0.5513 0.7173
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0022
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0112 0.0228 0.0412
Leishmania major importin beta-1 subunit, putative 0.0017 0 0.0001
Onchocerca volvulus 0.2316 0.5513 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0022
Treponema pallidum exodeoxyribonuclease (exoA) 0.0053 0.0087 0.3887
Trypanosoma cruzi heat shock protein 90, putative 0.0025 0.002 0.005
Echinococcus granulosus Tubulin beta 2C chain 0.0054 0.009 0.0117
Echinococcus multilocularis peroxisome assembly protein 26 0.0064 0.0113 0.0113
Mycobacterium tuberculosis Conserved protein 0.0039 0.0053 0.0131
Mycobacterium leprae Probable lipase LipE 0.0039 0.0053 0.0129
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0036 0.0047 0.0061
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0263 0.0591 0.107
Brugia malayi hypothetical protein 0.0101 0.0202 0.0367
Trypanosoma brucei alpha tubulin 0.0064 0.0113 0.0279
Echinococcus multilocularis 5' AMP activated protein kinase subunit gamma 0.0101 0.0203 0.0203
Loa Loa (eye worm) Smad1 0.0028 0.0027 0.0047
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0058 0.01 0.1755
Schistosoma mansoni rhodopsin-like orphan GPCR 0.2316 0.5513 1
Echinococcus multilocularis lipoxygenase domain containing protein 0.0239 0.0533 0.0533
Echinococcus multilocularis neuropeptides capa receptor 0.2316 0.5513 0.5513
Echinococcus granulosus beta tubulin 0.0054 0.009 0.0117
Leishmania major alpha tubulin 0.0064 0.0113 0.0279
Loa Loa (eye worm) 6-phosphofructokinase 0.0109 0.0223 0.0403
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.0117 0.0212
Echinococcus granulosus lipoxygenase domain containing protein 0.0239 0.0533 0.0693
Loa Loa (eye worm) hypothetical protein 0.0319 0.0726 0.1315
Echinococcus granulosus Polycystic kidney disease protein 0.0239 0.0533 0.0693
Echinococcus granulosus geminin 0.0948 0.2232 0.2904
Brugia malayi hypothetical protein 0.0239 0.0533 0.0967
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0022
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0058 0.01 0.1204
Schistosoma mansoni thyroid hormone receptor 0.0017 0.0002 0.0003
Brugia malayi Patched family protein 0.0022 0.0013 0.0024
Onchocerca volvulus 0.0101 0.0202 0.0363
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0053 0.0131
Mycobacterium tuberculosis Secreted antigen 85-B FbpB (85B) (antigen 85 complex B) (mycolyl transferase 85B) (fibronectin-binding protein B) (extracellular 0.0039 0.0055 0.0135
Trichomonas vaginalis set domain proteins, putative 0.0255 0.0571 1
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0051 0.0083 0.0206
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0022
Trichomonas vaginalis tubulin alpha chain, putative 0.0022 0.0013 0.0227
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0022 0.0013 0.0031
Loa Loa (eye worm) MH1 domain-containing protein 0.0028 0.0027 0.0047
Echinococcus granulosus single minded 2 0.0043 0.0065 0.0084
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Brugia malayi neuropeptide F receptor 0.2316 0.5513 1
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0039 0.0053 0.0132
Echinococcus granulosus Tubulin alpha 1 chain 0.0064 0.0113 0.0147
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.2316 0.5513 1
Schistosoma mansoni alpha tubulin 0.0064 0.0113 0.0205
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0037 0.0049 0.0581
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0075 0.0184
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0033 0.0039 0.005
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0004 0.0077
Echinococcus multilocularis tubulin alpha chain 0.0064 0.0113 0.0113
Echinococcus granulosus rhodopsin orphan GPCR 0.2316 0.5513 0.7173
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0017 0.0002 0.0003
Mycobacterium leprae SECRETED ANTIGEN 85-B FBPB (85B) (ANTIGEN 85 COMPLEX B) (MYCOLYL TRANSFERASE 85B) (FIBRONECTIN-BINDING PROTEIN B) (EXTRACELLULAR 0.0039 0.0055 0.0133
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0053 0.0087 0.0113
Leishmania major heat shock protein 83-1 0.0025 0.002 0.005
Brugia malayi exodeoxyribonuclease III family protein 0.0053 0.0087 0.0157
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0017 0.0002 0.0002
Schistosoma mansoni neuropeptide f receptor 76f 0.2316 0.5513 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.2316 0.5513 1
Brugia malayi Smad1 0.0028 0.0027 0.0049
Toxoplasma gondii patched family protein 0.0022 0.0013 0.0032
Brugia malayi inosine-5'-monophosphate dehydrogenase 0.0709 0.1661 0.3013
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0031 0.0548
Mycobacterium ulcerans secreted antigen 85-B FbpB 0.0039 0.0055 0.0135
Brugia malayi photoreceptor-specific nuclear receptor 0.0017 0.0002 0.0003
Echinococcus multilocularis neuropeptide receptor 0.2316 0.5513 0.5513
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0224 0.0497 0.0901
Leishmania major beta tubulin 0.0054 0.009 0.0222
Entamoeba histolytica tubulin family protein 0.0054 0.009 0.1081
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0036 0.0047 0.0061
Schistosoma mansoni chloride channel protein 0.0101 0.0203 0.0369
Trypanosoma cruzi zeta tubulin, putative 0.0017 0.0001 0.0002
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0075 0.0184
Loa Loa (eye worm) hypothetical protein 0.0042 0.006 0.0108
Loa Loa (eye worm) hypothetical protein 0.0125 0.0261 0.0471
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0022
Loa Loa (eye worm) hypothetical protein 0.0033 0.0039 0.0069
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0022
Trypanosoma brucei Heat shock protein 83, putative 0.0025 0.002 0.005
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0017 0.0002 0.0003
Schistosoma mansoni alpha-glucosidase 0.0226 0.0503 0.0912
Loa Loa (eye worm) melatonin receptor type 1A 0.2316 0.5513 1
Loa Loa (eye worm) hypothetical protein 0.0126 0.0263 0.0476
Echinococcus multilocularis lysosomal alpha glucosidase 0.0263 0.0591 0.0591
Leishmania major heat shock protein 83-1 0.0025 0.002 0.005
Schistosoma mansoni cpg binding protein 0.003 0.0033 0.006
Trypanosoma brucei epsilon tubulin 0.0039 0.0053 0.0132
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0058 0.01 0.1204
Echinococcus multilocularis heat shock protein 90 0.002 0.0008 0.0008
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0021 0.0056
Echinococcus multilocularis BC026374 protein (S09 family) 0.0101 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0021 0.0053
Mycobacterium ulcerans putative regulatory protein 0.0043 0.0065 0.0159
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0059 0.0102 0.0102
Echinococcus granulosus lysine specific demethylase 5A 0.0061 0.0107 0.0139
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0056 0.0094 0.165
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0031 0.1539
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0004 0.0077
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.2316 0.5513 1
Schistosoma mansoni hypothetical protein 0.2316 0.5513 1
Brugia malayi loechrig isoform VII 0.0101 0.0203 0.0369
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0056 0.0094 0.165
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0107 0.0193
Echinococcus multilocularis Protein lozenge 0.0039 0.0055 0.0055
Toxoplasma gondii patched family protein 0.0022 0.0013 0.0032
Plasmodium falciparum LCCL domain-containing protein 0.0239 0.0533 0.1399
Echinococcus granulosus importin subunit beta 1 0.0021 0.001 0.0013
Trichomonas vaginalis alpha-glucosidase, putative 0.0058 0.01 0.1755
Leishmania major heat shock protein 83-1 0.0025 0.002 0.005
Plasmodium falciparum thioredoxin reductase 0.0048 0.0075 0.0196
Loa Loa (eye worm) glutathione reductase 0.0048 0.0075 0.0134
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0053 0.0087 0.0214
Toxoplasma gondii beta tubulin 0.0054 0.009 0.0222
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0055 0.0096
Onchocerca volvulus 0.0039 0.0053 0.0093
Trichomonas vaginalis heat shock protein, putative 0.002 0.0008 0.0143
Loa Loa (eye worm) hypothetical protein 0.0039 0.0053 0.0095
Leishmania major alpha tubulin 0.0064 0.0113 0.0279
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.2316 0.5513 0.5513
Schistosoma mansoni polycystin 1-related 0.0239 0.0533 0.0967
Brugia malayi Putative carbonic anhydrase 5 precursor 0.1164 0.2752 0.4991
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Echinococcus multilocularis heat shock protein 90 0.0025 0.002 0.002
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0053 0.0053
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0031 0.0082
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0053 0.0087 0.0214
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0053 0.0929
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0547 0.1272 0.2307
Echinococcus multilocularis mitogen activated protein kinase 3 0.0051 0.0083 0.0083
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0125 0.0261 0.0643
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0017 0.0002 0.0003
Loa Loa (eye worm) tubulin alpha-3 chain 0.0042 0.006 0.0108
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0053 0.0139
Echinococcus multilocularis rhodopsin orphan GPCR 0.2316 0.5513 0.5513
Plasmodium falciparum inosine-5'-monophosphate dehydrogenase 0.1605 0.381 1
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0053 0.0087 0.0214
Leishmania major alpha tubulin 0.0064 0.0113 0.0279
Brugia malayi Patched family protein 0.0022 0.0013 0.0024
Schistosoma mansoni cellular tumor antigen P53 0.005 0.008 0.0145
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0075 0.0097
Toxoplasma gondii CBS domain-containing protein 0.0101 0.0203 0.0502
Schistosoma mansoni amine GPCR 0.2316 0.5513 1
Entamoeba histolytica heat shock protein 90, putative 0.0025 0.002 0.024
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0041 0.0058 0.1016
Echinococcus multilocularis alpha 1A adrenergic receptor 0.2316 0.5513 0.5513
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0053 0.0087 0.0087
Echinococcus granulosus neuropeptides capa receptor 0.2316 0.5513 0.7173
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Brugia malayi GnHR receptor homolog 0.2316 0.5513 1
Loa Loa (eye worm) intermediate filament protein 0.0058 0.0099 0.0178
Toxoplasma gondii exonuclease III APE 0.0053 0.0087 0.0214
Mycobacterium leprae Probable inosine-5'-monophosphate dehydrogenase GuaB3 (IMP dehydrogenase 2) (inosinic acid dehydrogenase) (inosinate dehydrogena 0.0896 0.2109 0.5203
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0049 0.0078 0.0193
Plasmodium vivax dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.0143 0.0303 0.0796
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0041 0.0058 0.1016
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0037 0.0049 0.012
Onchocerca volvulus 0.2316 0.5513 1
Echinococcus multilocularis beta tubulin 0.0054 0.009 0.009
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0109 0.0221 0.0545
Onchocerca volvulus 0.005 0.008 0.0141
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0062 0.0109
Plasmodium vivax heat shock protein 86, putative 0.0025 0.002 0.0053
Mycobacterium ulcerans hypothetical protein 0.0101 0.0203 0.0502
Echinococcus multilocularis rhodopsin orphan GPCR 0.2316 0.5513 0.5513
Echinococcus granulosus rhodopsin orphan GPCR 0.2316 0.5513 0.7173
Trichomonas vaginalis ap endonuclease, putative 0.0053 0.0087 0.1515
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0368 0.0843 0.1529
Echinococcus granulosus tubulin alpha chain 0.0064 0.0113 0.0147
Giardia lamblia Gamma tubulin 0.0039 0.0053 0.0971
Echinococcus multilocularis g protein coupled receptor 0.2316 0.5513 0.5513
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0031 0.0548
Brugia malayi jmjC domain containing protein 0.0059 0.0102 0.0186
Trichomonas vaginalis heat shock protein, putative 0.002 0.0008 0.0143
Echinococcus multilocularis endoplasmin 0.002 0.0008 0.0008
Schistosoma mansoni carbonic anhydrase 0.0547 0.1272 0.2307
Trypanosoma brucei Voltage-gated Chloride channel Like 1 0.0101 0.0203 0.0502
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.0101 0.0203 0.0502
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0083 0.146
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0049 0.0078 0.0193
Echinococcus granulosus fmrfamide receptor 0.2316 0.5513 0.7173
Schistosoma mansoni hypothetical protein 0.015 0.032 0.058
Trypanosoma brucei trypanothione reductase 0.0048 0.0075 0.0184
Schistosoma mansoni hypothetical protein 0.015 0.032 0.058
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0022
Giardia lamblia Beta tubulin 0.0054 0.009 0.1641
Mycobacterium leprae SECRETED ANTIGEN 85-C FBPC (85C) (ANTIGEN 85 COMPLEX C) (AG58C) (MYCOLYL TRANSFERASE 85C) (FIBRONECTIN-BINDING PROTEIN C) 0.0926 0.2181 0.5381
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0037 0.0049 0.0118
Loa Loa (eye worm) hypothetical protein 0.0101 0.0202 0.0365
Leishmania major heat shock protein 83-1 0.0025 0.002 0.005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Schistosoma mansoni hypothetical protein 0.0204 0.0449 0.0815
Loa Loa (eye worm) beta-tubulin 0.0054 0.009 0.0162
Echinococcus multilocularis biogenic amine (5HT) receptor 0.2316 0.5513 0.5513
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0037 0.0049 0.012
Loa Loa (eye worm) alpha-tubulin 0.0064 0.0113 0.0203
Schistosoma mansoni amine GPCR 0.2316 0.5513 1
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Loa Loa (eye worm) hypothetical protein 0.005 0.008 0.0143
Leishmania major heat shock protein 83-1 0.0025 0.002 0.005
Loa Loa (eye worm) hypothetical protein 0.0101 0.0202 0.0365
Mycobacterium tuberculosis Probable cystathionine beta-synthase Cbs (serine sulfhydrase) (beta-thionase) (hemoprotein H-450) 0.0101 0.0203 0.0502
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0017 0.0002 0.0002
Mycobacterium tuberculosis Secreted MPT51/MPB51 antigen protein FbpD (MPT51/MPB51 antigen 85 complex C) (AG58C) (mycolyl transferase 85C) (fibronectin-bind 0.0039 0.0055 0.0135
Trypanosoma brucei carbonic anhydrase-like protein 0.1164 0.2752 0.679
Mycobacterium ulcerans acyl-CoA synthetase 0.0037 0.0049 0.012
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0049 0.0078 0.0078
Schistosoma mansoni rhodopsin-like orphan GPCR 0.2316 0.5513 1
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0031 0.0082
Leishmania major heat shock protein 83-1 0.0025 0.002 0.005
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0101 0.0202 0.0499
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0109 0.0221 0.0543
Echinococcus multilocularis orexin receptor type 2 0.2316 0.5513 0.5513
Brugia malayi hypothetical protein 0.2316 0.5513 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0114 0.0233 0.0422
Schistosoma mansoni tubulin subunit beta 0.0017 0.0001 0.0001
Schistosoma mansoni smad1 5 8 and 0.0028 0.0027 0.0049
Onchocerca volvulus 0.2316 0.5513 1
Trichomonas vaginalis tubulin beta chain, putative 0.0022 0.0013 0.0227
Echinococcus multilocularis beta tubulin 0.0054 0.009 0.009
Giardia lamblia Alpha-tubulin 0.0064 0.0113 0.2056
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0051 0.0083 0.0206
Schistosoma mansoni protein kinase subunit gamma 0.0101 0.0203 0.0369
Brugia malayi beta-lactamase 0.0039 0.0053 0.0096
Trypanosoma cruzi tubulin delta chain 0.0017 0.0001 0.0002
Treponema pallidum hemolysin (tlyC) 0.0101 0.0203 0.9135
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0002
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0051 0.0083 0.0206
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.1164 0.2752 0.4991
Loa Loa (eye worm) MH2 domain-containing protein 0.0028 0.0027 0.0047
Brugia malayi Melatonin receptor type 1A 0.2316 0.5513 1
Echinococcus multilocularis lipoxygenase domain containing protein 0.0239 0.0533 0.0533
Trypanosoma brucei heat shock protein, putative 0.0025 0.002 0.005
Brugia malayi hypothetical protein 0.2316 0.5513 1
Brugia malayi CHE-14 protein 0.0156 0.0333 0.0605
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0037 0.0049 0.0087
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0121 0.025 0.0616
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.2316 0.5513 1
Echinococcus granulosus sex peptide receptor 0.2316 0.5513 0.7173
Schistosoma mansoni neuropeptide receptor 0.2316 0.5513 1
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0037 0.0049 0.012
Schistosoma mansoni adenoreceptor 0.2316 0.5513 1
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0053 0.0131
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0031 0.0548
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.2316 0.5513 0.5513
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0037 0.0049 0.0088
Echinococcus granulosus tubulin subunit beta 0.0054 0.009 0.0117
Onchocerca volvulus 0.0058 0.0099 0.0176
Loa Loa (eye worm) hypothetical protein 0.2316 0.5513 1
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0037 0.0049 0.012
Trichomonas vaginalis tubulin epsilon chain, putative 0.0017 0.0001 0.0014
Schistosoma mansoni biogenic amine receptor 0.2316 0.5513 1
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0125 0.0261 0.0643
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0027 0.0476
Leishmania major beta tubulin 0.0054 0.009 0.0222
Echinococcus multilocularis Smad4 0.0028 0.0027 0.0027
Echinococcus multilocularis g protein coupled receptor 0.2316 0.5513 0.5513
Echinococcus granulosus Smad4 0.0028 0.0027 0.0035
Loa Loa (eye worm) hypothetical protein 0.0031 0.0034 0.0061
Echinococcus granulosus acetylcholinesterase 0.0596 0.139 0.1809
Trichomonas vaginalis spcc417.12 protein, putative 0.0101 0.0202 0.3536
Schistosoma mansoni peptide (allatostatin)-like receptor 0.2316 0.5513 1
Trichomonas vaginalis tubulin gamma chain, putative 0.0039 0.0053 0.0933
Onchocerca volvulus 0.2316 0.5513 1
Schistosoma mansoni hypothetical protein 0.0948 0.2232 0.4049
Schistosoma mansoni hypothetical protein 0.0036 0.0047 0.0085
Echinococcus granulosus rhodopsin orphan GPCR 0.2316 0.5513 0.7173
Leishmania major heat shock protein 83-1 0.0025 0.002 0.005
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0022
Mycobacterium ulcerans acyl-CoA synthetase 0.0125 0.0261 0.0643
Brugia malayi steroid hormone receptor 0.0017 0.0002 0.0003
Plasmodium vivax acyl-CoA synthetase, putative 0.0094 0.0185 0.0485
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.0049 0.012
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0037 0.0049 0.012
Schistosoma mansoni BC026374 protein (S09 family) 0.0101 0.0202 0.0367
Echinococcus granulosus tubulin alpha 3 chain 0.0064 0.0113 0.0147
Trypanosoma cruzi heat shock protein 85, putative 0.0025 0.002 0.005
Echinococcus granulosus alpha tubulin 0.0064 0.0113 0.0147
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0114 0.0233 0.0421
Plasmodium vivax tubulin epsilon chain, putative 0.0039 0.0053 0.014
Loa Loa (eye worm) hypothetical protein 0.0036 0.0047 0.0083
Onchocerca volvulus 0.0041 0.0059 0.0103
Loa Loa (eye worm) hypothetical protein 0.0101 0.0202 0.0365
Schistosoma mansoni biogenic amine (5HT) receptor 0.2316 0.5513 1

Activities

Activity type Activity value Assay description Source Reference
EC50 (binding) = 213 pM Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells ChEMBL. 10794683
EC50 (binding) = 213 pM Potency measured using recombinant human GLP-1 receptor expressed in Baby Hamster Kidney (BHK)cells ChEMBL. 10794683

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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