Detailed information for compound 401827

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1447.45 | Formula: C63H90N12O27
  • H donors: 23 H acceptors: 19 LogP: -6.69 Rotable bonds: 23
    Rule of 5 violations (Lipinski): 4
  • SMILES: OC[C@@H]1O[C@@H](Oc2ccc(cc2)C[C@@H]2NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC2=O)[C@H]([C@@H]2CNC(N2)N)O)[C@H]([C@@H]2CNC(N2[C@@H]2O[C@@H](CO)[C@H]([C@H]([C@@H]2OC)O)O)N)O)CO)[C@H](c2ccccc2)C)[C@H]([C@H]([C@@H]1O[C@@H]1O[C@@H](COC(=O)OCc2ccccc2)[C@H]([C@H]([C@@H]1O)O)O)O)O
  • InChi: 1S/C63H90N12O27/c1-26(29-11-7-4-8-12-29)39-55(91)69-31(17-27-13-15-30(16-14-27)98-59-50(88)48(86)51(36(23-78)100-59)102-60-49(87)46(84)45(83)37(101-60)25-97-63(94)96-24-28-9-5-3-6-10-28)54(90)73-40(42(80)32-18-67-61(64)71-32)57(93)74-41(56(92)70-33(21-76)53(89)66-20-38(79)72-39)43(81)34-19-68-62(65)75(34)58-52(95-2)47(85)44(82)35(22-77)99-58/h3-16,26,31-37,39-52,58-62,67-68,71,76-78,80-88H,17-25,64-65H2,1-2H3,(H,66,89)(H,69,91)(H,70,92)(H,72,79)(H,73,90)(H,74,93)/t26-,31+,32-,33-,34-,35+,36+,37+,39-,40-,41+,42-,43-,44+,45+,46-,47-,48+,49-,50-,51+,52-,58?,59-,60+,61?,62?/m0/s1
  • InChiKey: UQFBDPOQDURGKN-LHYAZZAGSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.009 0.0182 0.4595
Schistosoma mansoni hypothetical protein 0.0033 0.0037 0.0119
Trichomonas vaginalis PIKK family atypical protein kinase 0.0385 0.0934 0.4971
Leishmania major phosphatidylinositol 3-kinase, putative 0.0173 0.0394 0.1066
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.003
Schistosoma mansoni GTPase activating protein 0.0033 0.0037 0.0119
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0064 0.0115 0.0324
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0004 0.0004
Echinococcus granulosus netrin receptor unc 5 0.0037 0.0048 0.0044
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0559 0.138 0.7353
Loa Loa (eye worm) hypothetical protein 0.0047 0.0073 0.0253
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0008
Loa Loa (eye worm) guanylate kinase 0.0027 0.0022 0.0072
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.03 0.0717 0.3813
Schistosoma mansoni septate junction protein 0.0022 0.001 0.0022
Onchocerca volvulus 0.0028 0.0024 0.0066
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0031 0.0145
Schistosoma mansoni neuroglian 0.004 0.0055 0.0183
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0008
Loa Loa (eye worm) hypothetical protein 0.004 0.0055 0.0189
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0093 0.019 0.0187
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0064 0.0115 0.0596
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0043 0.0064 0.0173
Loa Loa (eye worm) TK/FER protein kinase 0.0047 0.0073 0.0253
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0008
Echinococcus multilocularis twitchin 0.0021 0.0007 0.0003
Schistosoma mansoni adapter molecule crk 0.006 0.0106 0.0367
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0053 0.0089 0.0085
Echinococcus granulosus tyrosine kinase 0.0263 0.0623 0.062
Loa Loa (eye worm) hypothetical protein 0.009 0.0182 0.064
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0064 0.0115 0.0596
Loa Loa (eye worm) hypothetical protein 0.004 0.0055 0.0189
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0239 0.0562 0.5695
Echinococcus multilocularis survival motor neuron protein 1 0.0492 0.1209 0.1206
Echinococcus granulosus suppressor of cytokine signaling 7 0.0033 0.0037 0.0033
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0464 0.2458
Trichomonas vaginalis CMGC family protein kinase 0.0143 0.0318 0.1678
Loa Loa (eye worm) TK/FER protein kinase 0.0047 0.0073 0.0253
Schistosoma mansoni C-fyn 0.0027 0.0022 0.0065
Schistosoma mansoni nephrin 0.0086 0.0173 0.0607
Echinococcus multilocularis voltage dependent calcium channel 0.0034 0.0038 0.0034
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0173 0.0394 0.2086
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0077 0.0149 0.0145
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0031 0.0679
Echinococcus granulosus serine:threonine protein kinase PLK1 0.02 0.0464 0.046
Entamoeba histolytica protein kinase domain containing protein 0.0143 0.0318 0.1678
Brugia malayi Casein kinase II, alpha chain 0.0143 0.0318 0.1125
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.0004 0.001
Plasmodium falciparum GAF domain-related protein, putative 0.002 0.0004 0.0058
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.02 0.0464 0.1637
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.004 0.0055 0.0183
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0064 0.0115 0.0596
Schistosoma mansoni cell adhesion molecule 0.0022 0.001 0.0022
Schistosoma mansoni casein kinase II beta subunit 0.0038 0.005 0.0167
Echinococcus multilocularis rho guanine nucleotide exchange factor 7 0.0027 0.0022 0.0018
Schistosoma mansoni hypothetical protein 0.0022 0.001 0.0022
Echinococcus multilocularis SH2 motif 0.0033 0.0037 0.0033
Loa Loa (eye worm) TK/FER protein kinase 0.0047 0.0073 0.0253
Trichomonas vaginalis PIKK family atypical protein kinase 0.0127 0.0276 0.1454
Brugia malayi PXA domain containing protein 0.0022 0.0008 0.0027
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0367 0.089 0.4733
Echinococcus granulosus tyrosine protein kinase shark 0.0047 0.0073 0.007
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0034 0.0038 0.0034
Brugia malayi Serotonin receptor 0.0487 0.1197 0.4233
Echinococcus multilocularis geminin 0.0176 0.0401 0.0397
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0022 0.001 0.003
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0024 0.008
Entamoeba histolytica hypothetical protein 0.0027 0.0022 0.0097
Onchocerca volvulus 0.0047 0.0073 0.0253
Entamoeba histolytica serine/threonine protein kinase, putative 0.02 0.0464 0.2458
Brugia malayi protein-tyrosine kinase 0.0263 0.0623 0.2205
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0034 0.0038 0.0034
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0173 0.0394 0.3983
Trichomonas vaginalis PIKK family atypical protein kinase 0.0385 0.0934 0.497
Loa Loa (eye worm) TK protein kinase 0.0263 0.0623 0.2201
Echinococcus granulosus Immunoglobulin subtype 0.0022 0.001 0.0006
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0664 0.1646 0.8773
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0043 0.0064 0.0319
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.02 0.0464 0.1256
Schistosoma mansoni hypothetical protein 0.0176 0.0401 0.1422
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0418 0.1019 0.3637
Echinococcus granulosus contactin 0.004 0.0055 0.0051
Loa Loa (eye worm) SRC-1 0.029 0.0693 0.2447
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0064 0.0115 0.0596
Onchocerca volvulus 0.0039 0.0052 0.0173
Schistosoma mansoni hypothetical protein 0.0033 0.0037 0.0119
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0034 0.0038 0.0034
Schistosoma mansoni netrin receptor unc5 0.0022 0.001 0.0022
Echinococcus granulosus tyrosine protein kinase Blk 0.0263 0.0623 0.062
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0418 0.1019 0.296
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0053 0.0089 0.086
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0544 0.134 0.4741
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0049 0.0045
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0428 0.1044 1
Schistosoma mansoni growth factor receptor-bound protein 0.006 0.0106 0.0367
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.009 0.0182 0.0645
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0032 0.01
Trypanosoma cruzi hypothetical protein, conserved 0.1364 0.3433 1
Echinococcus granulosus roundabout 2 0.004 0.0055 0.0051
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0027 0.0022 0.0018
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.009 0.0182 0.0954
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0418 0.1019 0.1016
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0004 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0149 0.0332 0.1754
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0022 0.0097
Trichomonas vaginalis PIKK family atypical protein kinase 0.0428 0.1044 0.556
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0032 0.0033 0.003
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.003
Loa Loa (eye worm) hypothetical protein 0.0149 0.0332 0.117
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0022 0.001 0.0006
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0064 0.0115 0.0324
Trypanosoma cruzi polo-like protein kinase, putative 0.02 0.0464 0.134
Trichomonas vaginalis PIKK family atypical protein kinase 0.0385 0.0934 0.4971
Loa Loa (eye worm) hypothetical protein 0.0033 0.0037 0.0126
Loa Loa (eye worm) hypothetical protein 0.0033 0.0037 0.0126
Schistosoma mansoni dynamin-associated protein 0.0027 0.0022 0.0065
Onchocerca volvulus 0.0047 0.0073 0.0253
Trichomonas vaginalis set domain proteins, putative 0.0246 0.0579 0.3074
Trichomonas vaginalis PIKK family atypical protein kinase 0.0279 0.0665 0.3533
Trichomonas vaginalis conserved hypothetical protein 0.0127 0.0276 0.1454
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0028 0.0024 0.0087
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0047 0.0073 0.0069
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.004 0.0055 0.0189
Mycobacterium leprae conserved hypothetical protein 0.009 0.0182 0.7471
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0031 0.0271
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0033 0.0037 0.0116
Schistosoma mansoni septate junction protein 0.0022 0.001 0.0022
Schistosoma mansoni hypothetical protein 0.0022 0.001 0.0022
Loa Loa (eye worm) hypothetical protein 0.0069 0.0128 0.0449
Brugia malayi Voltage-dependent L-type calcium channel beta-2 subunit 0.0187 0.0429 0.1519
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0336 0.0809 0.0806
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0064 0.0115 0.0596
Onchocerca volvulus 0.0028 0.0024 0.0066
Loa Loa (eye worm) CYP4Cod1 0.002 0.0004 0.001
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0128 0.028 0.2653
Echinococcus multilocularis tumor protein p63 0.0353 0.0854 0.085
Brugia malayi Fes/CIP4 homology domain containing protein 0.0027 0.0022 0.0078
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0009 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0409 0.0995 0.5298
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0064 0.0115 0.0596
Trichomonas vaginalis PIKK family atypical protein kinase 0.0385 0.0934 0.497
Schistosoma mansoni tensin 0.0033 0.0037 0.0119
Entamoeba histolytica BAR/SH3 domain containing protein 0.0027 0.0022 0.0097
Onchocerca volvulus 0.009 0.0182 0.0668
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0118 0.0255 0.0251
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0142 0.0315 0.0906
Echinococcus multilocularis hemicentin 1 0.004 0.0055 0.0051
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0258 0.0611 0.5831
Loa Loa (eye worm) PXA domain-containing protein 0.0022 0.0008 0.0021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0409 0.0995 0.5298
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0031 0.0733
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0064 0.0115 0.0596
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0004 0.0013
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0008
Echinococcus granulosus serine protein kinase ATM 0.0232 0.0545 0.0541
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0209 0.1099
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0093 0.019 0.0187
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0034 0.0038 0.0034
Brugia malayi Immunoglobulin I-set domain containing protein 0.0069 0.0128 0.0454
Schistosoma mansoni SH2A 0.0033 0.0037 0.0119
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0105 0.0221 0.0633
Echinococcus multilocularis roundabout 2 0.0109 0.023 0.0227
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0754 0.1875 0.5457
Entamoeba histolytica hypothetical protein 0.0232 0.0545 0.289
Brugia malayi PAS domain containing protein 0.0051 0.0082 0.0291
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0072
Loa Loa (eye worm) hypothetical protein 0.0239 0.0562 0.1983
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0007 0.001
Plasmodium vivax glycogen synthase kinase 3, putative 0.0053 0.0089 0.2158
Schistosoma mansoni intermediate filament proteins 0.0028 0.0024 0.0072
Echinococcus multilocularis tyrosine protein kinase HCK 0.023 0.0539 0.0535
Brugia malayi Variant SH3 domain containing protein 0.006 0.0106 0.0376
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0022 0.001 0.0022
Entamoeba histolytica hypothetical protein 0.0027 0.0022 0.0097
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.009 0.0182 0.0645
Echinococcus granulosus low density lipoprotein receptor ldl 0.0022 0.001 0.0006
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0064 0.0115 0.1068
Onchocerca volvulus 0.0038 0.0049 0.016
Trypanosoma brucei conserved protein 0.0027 0.0022 0.0169
Loa Loa (eye worm) TK protein kinase 0.023 0.0539 0.1902
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.009 0.0182 0.0519
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.029 0.0693 0.0689
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0114 0.0243 0.0695
Onchocerca volvulus Tyrosine kinase homolog 0.1053 0.2639 1
Loa Loa (eye worm) hypothetical protein 0.0105 0.0221 0.0775
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0754 0.1875 1
Plasmodium vivax casein kinase II beta chain, putative 0.0038 0.005 0.1177
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0064 0.0115 0.0324
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0031 0.0145
Brugia malayi Immunoglobulin I-set domain containing protein 0.004 0.0055 0.0194
Echinococcus granulosus expressed conserved protein 0.0085 0.017 0.0166
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.009 0.0182 0.1818
Loa Loa (eye worm) thyroid receptor interactor 0.0027 0.0022 0.0072
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.005 0.0249
Schistosoma mansoni tyrosine kinase 0.0054 0.0091 0.0311
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.029 0.0693 0.0689
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0464 0.2458
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.009 0.0182 0.0179
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0033 0.0037 0.0119
Echinococcus granulosus lamin 0.0028 0.0024 0.002
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0114 0.0243 1
Echinococcus granulosus slit robo rho gtpase activating protein 1 0.0027 0.0022 0.0018
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.005 0.0249
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0336 0.0809 0.305
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0022 0.0097
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.02 0.0464 0.046
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0428 0.1044 0.556
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0347 0.0838 0.446
Echinococcus multilocularis musashi 0.0028 0.0024 0.002
Brugia malayi RhoGAP domain containing protein 0.0033 0.0037 0.0131
Trichomonas vaginalis PIKK family atypical protein kinase 0.0385 0.0934 0.4971
Trypanosoma cruzi casein kinase II, putative 0.0143 0.0318 0.0915
Brugia malayi Spectrin alpha chain 0.0027 0.0022 0.0078
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0022 0.001 0.003
Trichomonas vaginalis CMGC family protein kinase 0.0143 0.0318 0.1678
Loa Loa (eye worm) hypothetical protein 0.0033 0.0037 0.0126
Brugia malayi Immunoglobulin I-set domain containing protein 0.0037 0.0048 0.0171
Trichomonas vaginalis PIKK family atypical protein kinase 0.0365 0.0885 0.4709
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0032 0.0277
Mycobacterium tuberculosis Conserved hypothetical protein 0.009 0.0182 0.7471
Entamoeba histolytica hypothetical protein 0.0027 0.0022 0.0097
Echinococcus granulosus NCK adaptor protein 0.006 0.0106 0.0103
Echinococcus multilocularis signal transduction protein lnk realted 0.0033 0.0037 0.0033
Echinococcus multilocularis Immunoglobulin 0.0022 0.001 0.0006
Entamoeba histolytica hypothetical protein 0.0038 0.0049 0.024
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0173 0.0394 0.2086
Loa Loa (eye worm) Csnk2b protein 0.0038 0.005 0.0173
Echinococcus granulosus Immunoglobulin 0.0022 0.001 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0365 0.0885 0.4709
Brugia malayi 6-phosphofructokinase 0.0114 0.0243 0.0858
Onchocerca volvulus Serine\/threonine kinase homolog 0.02 0.0464 0.1738
Schistosoma mansoni hypothetical protein 0.0022 0.001 0.0022
Echinococcus granulosus tyrosine kinase 0.0047 0.0073 0.0069
Schistosoma mansoni vesicular amine transporter 0.0071 0.0133 0.0465
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0428 0.1044 0.3033
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0093 0.019 0.0668
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0072
Loa Loa (eye worm) hypothetical protein 0.0028 0.0024 0.008
Plasmodium vivax hypothetical protein 0.009 0.0182 0.4564
Onchocerca volvulus 0.0033 0.0037 0.0116
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.004 0.0055 0.0051
Brugia malayi Immunoglobulin domain containing protein 0.0022 0.001 0.0035
Echinococcus granulosus neuroglian 0.0086 0.0173 0.0169
Echinococcus granulosus lamin dm0 0.0028 0.0024 0.002
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0064 0.0115 0.0596
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0053 0.0089 0.0304
Entamoeba histolytica SH2 domain containing protein 0.0033 0.0037 0.0178
Echinococcus multilocularis tyrosine protein kinase shark 0.0047 0.0073 0.007
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0418 0.1019 0.1016
Onchocerca volvulus 0.0027 0.0022 0.0059
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0074 0.0142 0.0139
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0049 0.0161
Plasmodium vivax casein kinase II beta chain, putative 0.0038 0.005 0.1177
Leishmania major phosphatidylinositol 4-kinase, putative 0.009 0.0182 0.0487
Loa Loa (eye worm) calcium channel 0.0034 0.0038 0.013
Entamoeba histolytica unconventional myosin IB 0.0027 0.0022 0.0097
Schistosoma mansoni tyrosine kinase 0.0074 0.0142 0.0496
Echinococcus granulosus expressed conserved protein 0.0033 0.0037 0.0033
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.004 0.0055 0.0051
Echinococcus multilocularis SH2 motif 0.0033 0.0037 0.0033
Echinococcus granulosus tyrosine protein kinase otk 0.004 0.0055 0.0051
Echinococcus granulosus intersectin 2 0.0028 0.0024 0.0021
Brugia malayi Immunoglobulin I-set domain containing protein 0.0021 0.0007 0.0023
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.001 0.0035
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0217 0.0506 0.0502
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0173 0.0394 0.3749
Onchocerca volvulus 0.0105 0.0221 0.0813
Entamoeba histolytica hypothetical protein 0.0027 0.0022 0.0097
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0033 0.0037 0.0119
Schistosoma mansoni suppressor of cytokine signaling 0.0033 0.0037 0.0119
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0173 0.0394 0.0391
Echinococcus granulosus Spectrin alpha actinin 0.0027 0.0022 0.0018
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.009 0.0182 0.0179
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0031 0.0145
Brugia malayi hypothetical protein 0.0069 0.0128 0.0454
Trichomonas vaginalis PIKK family atypical protein kinase 0.0404 0.0983 0.5232
Echinococcus multilocularis cyclin dependent kinase 19 0.014 0.0309 0.0306
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0173 0.0394 0.0391
Brugia malayi 6-phosphofructokinase 0.0114 0.0243 0.0858
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0091 0.0186 0.0182
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0064 0.0115 0.0596
Echinococcus multilocularis roundabout 2 0.004 0.0055 0.0051
Schistosoma mansoni cell adhesion molecule 0.0022 0.001 0.0022
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0149 0.0332 0.0328
Schistosoma mansoni 6-phosphofructokinase 0.0114 0.0243 0.0855
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.021 0.0488 0.141
Schistosoma mansoni hypothetical protein 0.0054 0.0089 0.0307
Onchocerca volvulus 0.0047 0.0073 0.0253
Schistosoma mansoni basigin related 0.0022 0.001 0.0022
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0022 0.001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0033 0.0037 0.0126
Brugia malayi SH2 domain containing protein 0.0033 0.0037 0.0131
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.002 0.0004 0.0008
Echinococcus granulosus hematopoietic lineage cell specific protein 0.0027 0.0022 0.0018
Echinococcus multilocularis beta adrenergic receptor kinase 0.0024 0.0013 0.0009
Brugia malayi A-kinase anchor protein 10, precursor 0.002 0.0004 0.0013
Brugia malayi tRNA modification GTPase TrmE family protein 0.0033 0.0037 0.0131
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0033 0.0037 0.0116
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0043 0.0062 0.0208
Echinococcus granulosus tyrosine protein kinase ABL1 0.0047 0.0073 0.0069
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.009 0.0182 0.4564
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.009 0.0182 0.1818
Loa Loa (eye worm) phosphatidylinositol 3 0.021 0.0488 0.1721
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0064 0.0115 0.0596
Brugia malayi Guanylate kinase family protein 0.0035 0.0043 0.0152
Trichomonas vaginalis PIKK family atypical protein kinase 0.0232 0.0545 0.289
Echinococcus multilocularis hemicentin 1 0.004 0.0055 0.0051
Brugia malayi Cytochrome P450 family protein 0.002 0.0004 0.0015
Plasmodium vivax hypothetical protein, conserved 0.009 0.0182 0.4564
Echinococcus granulosus intermediate filament protein 0.0028 0.0024 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.009 0.0182 0.0954
Brugia malayi Variant SH3 domain containing protein 0.0027 0.0022 0.0078
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0047 0.0073 0.0069
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0008
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0053 0.0089 0.0308
Brugia malayi Immunoglobulin I-set domain containing protein 0.004 0.0055 0.0194
Schistosoma mansoni septate junction protein 0.004 0.0055 0.0183
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0072
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.03 0.0717 0.2538
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0032 0.0028
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.0004 0.001
Schistosoma mansoni fkbp-rapamycin associated protein 0.0217 0.0506 0.1798
Entamoeba histolytica hypothetical protein 0.0627 0.1552 0.8273
Trichomonas vaginalis CMGC family protein kinase 0.0143 0.0318 0.1678
Brugia malayi Variant SH3 domain containing protein 0.0027 0.0022 0.0078
Loa Loa (eye worm) hypothetical protein 0.0031 0.0032 0.0107
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0064 0.0115 0.0112
Schistosoma mansoni lamin 0.0028 0.0024 0.0072
Brugia malayi Protein kinase domain containing protein 0.0047 0.0073 0.0258
Loa Loa (eye worm) 6-phosphofructokinase 0.0114 0.0243 0.0853
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.005 0.0249
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0072
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0053 0.0089 0.0246
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0754 0.1875 1
Brugia malayi hypothetical protein 0.0022 0.001 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0022 0.0097
Echinococcus granulosus tensin 0.0033 0.0037 0.0033
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0243 0.1276
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0064 0.0115 0.04
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0464 0.2458
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.3937 1 1
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0243 0.1276
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0037 0.0046 0.0226
Schistosoma mansoni tyrosine kinase 0.0047 0.0073 0.0249
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0173 0.0394 0.0391
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0072
Echinococcus multilocularis c src tyrosine kinase 0.0074 0.0142 0.0139
Echinococcus granulosus cyclin dependent kinase 19 0.014 0.0309 0.0306
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.005 0.0249
Loa Loa (eye worm) hypothetical protein 0.0033 0.0037 0.0126
Trichomonas vaginalis PIKK family atypical protein kinase 0.0255 0.0604 0.3205
Loa Loa (eye worm) hypoxia-induced factor 1 0.0157 0.0354 0.1248
Echinococcus granulosus basement membrane specific heparan sulfate 0.0022 0.001 0.0006
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0263 0.0623 0.062
Onchocerca volvulus 0.009 0.0182 0.0668
Giardia lamblia Kinase, PLK 0.02 0.0464 0.422
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0143 0.0318 0.8042
Echinococcus multilocularis growth factor receptor bound protein 2 0.006 0.0106 0.0103
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0028 0.0024 0.0021
Mycobacterium ulcerans putative regulatory protein 0.002 0.0004 0.0007
Echinococcus multilocularis tyrosine protein kinase Abl 0.0074 0.0142 0.0139
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0559 0.138 0.7353
Echinococcus granulosus tyrosine protein kinase Lyn 0.0294 0.0702 0.0698
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0095 0.0489
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0064 0.0115 0.0596
Echinococcus granulosus breast cancer anti estrogen resistance protein 0.0027 0.0022 0.0018
Brugia malayi Variant SH3 domain containing protein 0.0027 0.0022 0.0078
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0409 0.0996 0.2709
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0114 0.0243 1
Echinococcus granulosus rho guanine nucleotide exchange factor 7 0.0027 0.0022 0.0018
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0031 0.0733
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0027 0.0022 0.0018
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0008
Echinococcus multilocularis tyrosine protein kinase Src42A 0.029 0.0693 0.0689
Loa Loa (eye worm) TK/FER protein kinase 0.0047 0.0073 0.0253
Schistosoma mansoni basigin related 0.0022 0.001 0.0022
Schistosoma mansoni serine/threonine protein kinase 0.0024 0.0013 0.0032
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1126 0.2827 1
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0027 0.0022 0.0065
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0033 0.0037 0.0119
Onchocerca volvulus 0.0047 0.0073 0.0253
Trichomonas vaginalis neutrophil cytosolic factor 2, neutrophil NADPH oxidase factor, putative 0.0027 0.0022 0.0097
Plasmodium falciparum casein kinase II beta chain 0.0038 0.005 0.1228
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.009 0.0182 0.1818
Leishmania major protein kinase ck2 regulatory subunit, putative 0.0038 0.005 0.0126
Schistosoma mansoni serine/threonine protein kinase 0.02 0.0464 0.1648
Onchocerca volvulus Netrin receptor homolog 0.0033 0.0036 0.0111
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.1114 0.2796 0.2793
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0114 0.0243 0.2291
Schistosoma mansoni tyrosine kinase 0.0074 0.0142 0.0496
Schistosoma mansoni hypothetical protein 0.009 0.0182 0.064
Echinococcus granulosus high voltage activated calcium channel beta 0.0091 0.0184 0.018
Echinococcus granulosus suppressor of cytokine signaling 6 0.0033 0.0037 0.0033
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.005 0.0249
Giardia lamblia Kinase, CMGC GSK 0.0053 0.0089 0.0562
Schistosoma mansoni vav2 0.0033 0.0037 0.0119
Echinococcus multilocularis tyrosine protein kinase Fgr 0.029 0.0693 0.0689
Brugia malayi Tensin 0.0033 0.0037 0.0131
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0064 0.0115 0.0596
Brugia malayi SH3 domain containing protein 0.0027 0.0022 0.0078
Brugia malayi Sex muscle abnormal protein 5 0.006 0.0106 0.0376
Loa Loa (eye worm) hypothetical protein 0.0033 0.0037 0.0126
Echinococcus multilocularis N chimaerin 0.0033 0.0037 0.0033
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.001 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.009 0.0182 0.0954
Onchocerca volvulus 0.0027 0.0022 0.0059
Loa Loa (eye worm) hypothetical protein 0.004 0.0055 0.0189
Echinococcus granulosus tumor protein p63 0.0353 0.0854 0.085
Schistosoma mansoni formin binding protein and related proteins 0.0027 0.0022 0.0065
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0848 0.2116 0.2113
Echinococcus granulosus hemicentin 1 0.004 0.0055 0.0051
Echinococcus multilocularis tyrosine protein kinase Fyn 0.029 0.0693 0.0689
Loa Loa (eye worm) hypothetical protein 0.0034 0.0038 0.013
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0064 0.0115 0.0112
Echinococcus multilocularis SH2 motif 0.0033 0.0037 0.0033
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0428 0.1044 1
Loa Loa (eye worm) TK/FER protein kinase 0.0047 0.0073 0.0253
Schistosoma mansoni netrin receptor unc5 0.0037 0.0048 0.0159
Schistosoma mansoni hypothetical protein 0.0027 0.0022 0.0065
Schistosoma mansoni hypothetical protein 0.0149 0.0332 0.1176
Echinococcus multilocularis endophilin A3 0.0027 0.0022 0.0018
Echinococcus multilocularis expressed protein 0.039 0.0948 0.0945
Loa Loa (eye worm) hypothetical protein 0.0033 0.0037 0.0126
Brugia malayi protein-tyrosine kinase 0.0027 0.0022 0.0078
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0033 0.0037 0.0033
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0064 0.0115 0.0596
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0064 0.0115 0.0596
Loa Loa (eye worm) hypothetical protein 0.0033 0.0037 0.0126
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0064 0.0115 0.0596
Loa Loa (eye worm) RecQ helicase 0.0022 0.0009 0.0027
Leishmania major hypothetical protein, conserved 0.0027 0.0022 0.0048
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0216 0.0503 0.1775
Trichomonas vaginalis CMGC family protein kinase 0.0143 0.0318 0.1678
Giardia lamblia Kinase, CMGC CK2 0.0143 0.0318 0.2797
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.005 0.0249
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0541 0.1334 0.1331
Loa Loa (eye worm) hypothetical protein 0.0069 0.0128 0.0449
Onchocerca volvulus 0.0052 0.0085 0.0296
Trypanosoma cruzi paraflagellar rod protein 5, putative 0.0027 0.0022 0.0051
Brugia malayi SH2 domain containing protein 0.0383 0.093 0.3291
Schistosoma mansoni serine/threonine protein kinase 0.0336 0.0809 0.2886
Loa Loa (eye worm) hypothetical protein 0.0091 0.0186 0.0651
Brugia malayi Cytochrome P450 family protein 0.0031 0.0032 0.0113
Echinococcus multilocularis hematopoietic lineage cell specific protein 0.0027 0.0022 0.0018
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0464 0.2458
Mycobacterium ulcerans 6-phosphofructokinase 0.0114 0.0243 1
Leishmania major casein kinase II, putative 0.0143 0.0318 0.0857
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0034 0.0038 0.0034
Loa Loa (eye worm) hypothetical protein 0.0069 0.0128 0.0449
Onchocerca volvulus 0.0033 0.0037 0.0116
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.009 0.0182 0.1712
Entamoeba histolytica hypothetical protein 0.009 0.0182 0.0954
Loa Loa (eye worm) hypothetical protein 0.0027 0.0023 0.0075
Brugia malayi Protein kinase domain containing protein 0.0047 0.0073 0.0258
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0033 0.0037 0.0033
Entamoeba histolytica protein kinase, putative 0.023 0.0539 0.2859
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0428 0.1044 0.3033
Loa Loa (eye worm) TK/FER protein kinase 0.0047 0.0073 0.0253
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0009 0.0028
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.03 0.0717 0.3813
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0074 0.0142 0.0139
Loa Loa (eye worm) TK/FER protein kinase 0.0047 0.0073 0.0253
Trichomonas vaginalis PIKK family atypical protein kinase 0.0409 0.0995 0.5298
Echinococcus multilocularis casein kinase ii subunit alpha 0.0143 0.0318 0.0314
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0034 0.0038 0.0135
Loa Loa (eye worm) hypothetical protein 0.0171 0.0388 0.1368
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0034 0.0038 0.0123
Echinococcus granulosus tyrosine protein kinase Src42A 0.029 0.0693 0.0689
Schistosoma mansoni hypothetical protein 0.0176 0.0401 0.1422
Loa Loa (eye worm) hypothetical protein 0.0105 0.0221 0.0776
Loa Loa (eye worm) phosphatidylinositol 3 0.009 0.0182 0.064
Brugia malayi Protein kinase domain containing protein 0.0047 0.0073 0.0258
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0022 0.001 0.0006
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0228 0.0534 0.2835
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0072
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.0243 0.1276
Echinococcus multilocularis expressed protein 0.0027 0.0022 0.0018
Schistosoma mansoni cell adhesion molecule 0.004 0.0055 0.0183
Brugia malayi Immunoglobulin I-set domain containing protein 0.1126 0.2827 1
Entamoeba histolytica hypothetical protein 0.009 0.0182 0.0954
Trichomonas vaginalis PIKK family atypical protein kinase 0.0389 0.0947 0.5037
Schistosoma mansoni titin 0.004 0.0055 0.0183
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0418 0.1019 0.3606
Trichomonas vaginalis PIKK family atypical protein kinase 0.0385 0.0934 0.4971
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0032 0.01
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0031 0.0679
Trypanosoma brucei Casein kinase II 0.0143 0.0318 0.3015
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0173 0.0394 0.1137
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.009 0.0182 0.0179
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.0243 0.1276
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0038 0.005 0.0167
Schistosoma mansoni hypothetical protein 0.01 0.0209 0.0735
Loa Loa (eye worm) phosphatidylinositol kinase 0.009 0.0182 0.064
Schistosoma mansoni tensin 0.0033 0.0037 0.0119
Echinococcus granulosus expressed protein 0.039 0.0948 0.0945
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0072
Loa Loa (eye worm) LAD-2 short isoform 0.0022 0.001 0.003
Brugia malayi follicle stimulating hormone receptor 0.0247 0.0583 0.2063
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0028 0.0024 0.0074
Brugia malayi Variant SH3 domain containing protein 0.0033 0.0037 0.0131
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0232 0.0545 0.1938
Brugia malayi Protein kinase domain containing protein 0.0047 0.0073 0.0258
Giardia lamblia Kinase, CMGC GSK 0.0053 0.0089 0.0562
Echinococcus multilocularis peroxidasin 0.004 0.0055 0.0051
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0033 0.0037 0.0131
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0173 0.0394 0.1398
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.009 0.0182 0.4564
Echinococcus multilocularis SH2 domain containing protein 7 0.0033 0.0037 0.0033
Echinococcus granulosus fch and double sh3 domains protein 2 0.0027 0.0022 0.0018
Echinococcus multilocularis transfer RNA-Ala 0.0027 0.0022 0.0018
Loa Loa (eye worm) hypothetical protein 0.026 0.0615 0.2172
Giardia lamblia Phosphatidylinositol 4-kinase 0.009 0.0182 0.1476
Schistosoma mansoni sh3-containing grb2-like protein 1 (endophilin II) 0.0027 0.0022 0.0065
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0033 0.0037 0.0119
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0049 0.0045
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.035 0.0845 0.3012
Loa Loa (eye worm) hypothetical protein 0.0541 0.1334 0.4716
Loa Loa (eye worm) protein-tyrosine kinase 0.0027 0.0022 0.0072
Echinococcus multilocularis breast cancer anti estrogen resistance protein 0.0027 0.0022 0.0018
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0377 0.0914 0.2486
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.01 0.0209 0.0739
Toxoplasma gondii ck2 beta subunit 0.0038 0.005 0.0469
Trichomonas vaginalis PIKK family atypical protein kinase 0.0282 0.0672 0.357
Schistosoma mansoni tyrosine kinase 0.029 0.0693 0.2468
Schistosoma mansoni septate junction protein 0.004 0.0055 0.0183
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0149 0.0332 0.0328
Echinococcus granulosus tyrosine protein kinase Fyn 0.029 0.0693 0.0689
Trichomonas vaginalis PIKK family atypical protein kinase 0.0228 0.0534 0.2835
Trichomonas vaginalis PIKK family atypical protein kinase 0.0109 0.0231 0.1215
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0095 0.0489
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0027 0.0022 0.0072
Loa Loa (eye worm) hypothetical protein 0.0217 0.0506 0.1785
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.004 0.0055 0.0051
Entamoeba histolytica hypothetical protein, conserved 0.0027 0.0022 0.0097
Onchocerca volvulus 0.0033 0.0037 0.0116
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0033 0.0037 0.0033
Leishmania major phosphatidylinositol kinase related protein, putative 0.0105 0.0221 0.0593
Schistosoma mansoni cell adhesion molecule 0.004 0.0055 0.0183
Loa Loa (eye worm) 6-phosphofructokinase 0.0114 0.0243 0.0853
Trypanosoma brucei Casein kinase II subunit beta, putative 0.0038 0.005 0.0442
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0038 0.005 0.0134
Toxoplasma gondii CMGC kinase, CK2 family 0.0143 0.0318 0.3203
Echinococcus multilocularis 0.009 0.0182 0.0179
Brugia malayi SH2 domain containing protein 0.0033 0.0037 0.0131
Schistosoma mansoni dreadlocks/dock 0.0027 0.0022 0.0065
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0064 0.0115 0.0596
Trichomonas vaginalis PIKK family atypical protein kinase 0.0365 0.0885 0.4709
Echinococcus granulosus twitchin 0.009 0.0182 0.0178
Echinococcus multilocularis expressed conserved protein 0.0085 0.017 0.0166
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.005 0.0249
Loa Loa (eye worm) TK/FER protein kinase 0.0047 0.0073 0.0253
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.006 0.0106 0.0367
Brugia malayi STAT protein, DNA binding domain containing protein 0.0033 0.0037 0.0131
Schistosoma mansoni suppressor of cytokine signaling 0.0033 0.0037 0.0119
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0232 0.0545 0.5196
Trichomonas vaginalis PIKK family atypical protein kinase 0.0255 0.0604 0.3205
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0541 0.1334 0.1331
Schistosoma mansoni tensin 0.0033 0.0037 0.0119
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0217 0.0506 0.0502
Brugia malayi regulator of G-protein signaling egl-10 0.002 0.0004 0.0013
Echinococcus multilocularis netrin receptor unc 5 0.0037 0.0048 0.0044
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0033 0.0037 0.0126
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0034 0.0039 0.0134
Echinococcus granulosus lachesin 0.004 0.0055 0.0051
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0033 0.0037 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.0404 0.0983 0.5232
Echinococcus multilocularis protein kinase shaggy 0.0053 0.0089 0.0085
Echinococcus multilocularis NCK adaptor protein 0.006 0.0106 0.0103
Brugia malayi hypothetical protein 0.0105 0.0221 0.0781
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0028 0.0024 0.0111
Echinococcus multilocularis epidermal growth factor receptor kinase 0.0027 0.0022 0.0018
Schistosoma mansoni tensin-related 0.0033 0.0037 0.0119
Onchocerca volvulus 0.1021 0.2558 0.9693
Onchocerca volvulus 0.0033 0.0037 0.0116
Loa Loa (eye worm) hypothetical protein 0.0109 0.023 0.081
Trichomonas vaginalis PIKK family atypical protein kinase 0.0404 0.0983 0.5232
Entamoeba histolytica protein kinase rad3, putative 0.0217 0.0506 0.2682
Schistosoma mansoni single-minded 0.0051 0.0082 0.0282
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0336 0.0809 0.0806
Trichomonas vaginalis PIKK family atypical protein kinase 0.0404 0.0983 0.5232
Echinococcus granulosus beta-adrenergic receptor kinase 0.0024 0.0013 0.0009
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0031 0.0145
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0464 0.2458
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0433 0.1057 1
Echinococcus multilocularis Spectrin alpha actinin 0.0027 0.0022 0.0018
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0064 0.0115 0.0596
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0024 0.0013 0.0045
Trichomonas vaginalis CMGC family protein kinase 0.0143 0.0318 0.1678
Schistosoma mansoni cell polarity protein 0.0035 0.0043 0.014
Echinococcus granulosus nostrin 0.0027 0.0022 0.0018
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0031 0.5
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0377 0.0914 0.8743
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.009 0.0182 0.0645
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.0032 0.0107
Loa Loa (eye worm) phosphatidylinositol 3-kinase catalytic subunit gamma 0.005 0.008 0.0278
Entamoeba histolytica hypothetical protein 0.0038 0.0049 0.024
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.014 0.0309 0.109
Brugia malayi regulator of G-protein signaling rgs-7 0.002 0.0004 0.0013
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.009 0.0182 0.0519
Schistosoma mansoni tyrosine kinase 0.0047 0.0073 0.0248
Brugia malayi hypothetical protein 0.002 0.0004 0.0013
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0031 0.0145
Echinococcus granulosus tyrosine protein kinase Fyn 0.029 0.0693 0.0689
Brugia malayi Peripheral plasma membrane protein CASK 0.0035 0.0043 0.0152
Schistosoma mansoni hypothetical protein 0.0085 0.017 0.0596
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0009 0.0032
Echinococcus granulosus Immunoglobulin 0.0069 0.0128 0.0125
Trichomonas vaginalis CMGC family protein kinase 0.0143 0.0318 0.1678
Brugia malayi Protein kinase domain containing protein 0.0047 0.0073 0.0258
Schistosoma mansoni tyrosine kinase 0.029 0.0693 0.2468
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0418 0.1019 0.296
Echinococcus multilocularis neuroglian 0.004 0.0055 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0409 0.0995 0.5298
Schistosoma mansoni tensin-related 0.0033 0.0037 0.0119
Brugia malayi Prion-like- 0.004 0.0055 0.0194
Entamoeba histolytica protein kinase domain containing protein 0.0053 0.0089 0.0453
Brugia malayi Immunoglobulin I-set domain containing protein 0.004 0.0055 0.0194
Brugia malayi intermediate filament protein 0.0028 0.0024 0.0085
Toxoplasma gondii FATC domain-containing protein 0.0232 0.0545 0.5521
Trypanosoma cruzi target of rapamycin kinase 3 0.0409 0.0996 0.2891
Echinococcus multilocularis Immunoglobulin 0.0022 0.001 0.0006
Brugia malayi Protein kinase domain containing protein 0.014 0.0309 0.1095
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0053 0.0089 0.0308
Loa Loa (eye worm) hypothetical protein 0.0033 0.0037 0.0126
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0031 0.0271
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0053 0.0089 0.0085
Echinococcus granulosus SH2 motif 0.0033 0.0037 0.0033
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0021 0.0007 0.0018
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0033 0.0037 0.0033
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0022 0.001 0.0006
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0069 0.0128 0.0446
Loa Loa (eye worm) TK/ROR protein kinase 0.0032 0.0033 0.0113
Schistosoma mansoni growth factor receptor-bound protein 0.006 0.0106 0.0367
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.005 0.0249
Loa Loa (eye worm) hypothetical protein 0.0033 0.0037 0.0126
Loa Loa (eye worm) hypothetical protein 0.0142 0.0315 0.111
Schistosoma mansoni roundabout 0.004 0.0055 0.0183
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0032 0.01
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0022 0.0097
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.005 0.0249
Schistosoma mansoni signal transducing adapter molecule (stam) 0.0027 0.0022 0.0065
Loa Loa (eye worm) hypothetical protein 0.004 0.0055 0.0189
Brugia malayi Heparan sulfate 0.0022 0.001 0.0035
Schistosoma mansoni serine/threonine protein kinase 0.014 0.0309 0.1095
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0022 0.001 0.0006
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0143 0.0318 0.112
Trichomonas vaginalis p67phox protein, putative 0.0027 0.0022 0.0097
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0022 0.001 0.0022
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0428 0.1044 0.556
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0022 0.001 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0389 0.0947 0.5037
Leishmania major hypothetical protein, unknown function 0.009 0.0182 0.0487
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0232 0.0545 0.1576
Echinococcus granulosus tyrosine protein kinase Fyn 0.029 0.0693 0.0689
Entamoeba histolytica hypothetical protein 0.0038 0.0049 0.024
Trichomonas vaginalis PIKK family atypical protein kinase 0.026 0.0616 0.3271
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0064 0.0115 0.0596
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0024 0.0085
Onchocerca volvulus 0.01 0.0209 0.0769
Echinococcus granulosus hypothetical protein 0.0033 0.0037 0.0033
Echinococcus granulosus voltage dependent calcium channel 0.0034 0.0038 0.0034
Echinococcus multilocularis lamin dm0 0.0028 0.0024 0.002
Brugia malayi Peroxidasin 0.004 0.0055 0.0194
Echinococcus granulosus SH2 motif 0.0033 0.0037 0.0033
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0217 0.0506 0.4626
Brugia malayi hypothetical protein 0.002 0.0004 0.0013
Schistosoma mansoni hypothetical protein 0.0022 0.001 0.0022
Trypanosoma brucei polo-like protein kinase 0.02 0.0464 0.4419
Trypanosoma cruzi polo-like protein kinase, putative 0.02 0.0464 0.134
Schistosoma mansoni nephrin 0.004 0.0055 0.0183
Brugia malayi Immunoglobulin I-set domain containing protein 0.004 0.0055 0.0194
Leishmania major hypothetical protein, conserved 0.1454 0.3663 1
Echinococcus multilocularis tyrosine protein kinase otk 0.004 0.0055 0.0051
Echinococcus multilocularis serine protein kinase ATM 0.0232 0.0545 0.0541
Echinococcus multilocularis tyrosine protein kinase Blk 0.0263 0.0623 0.062
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0089 0.0453
Onchocerca volvulus 0.0033 0.0037 0.0116
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0243 0.1276
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.0243 0.1276
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0173 0.0394 0.2086
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0069 0.0128 0.0125
Onchocerca volvulus 0.0027 0.0022 0.0059
Brugia malayi protein unc-22 0.0021 0.0007 0.0023
Echinococcus granulosus 6 phosphofructokinase 0.0114 0.0243 0.0239
Brugia malayi FAT domain containing protein 0.0149 0.0332 0.1175
Schistosoma mansoni serine/threonine protein kinase 0.0024 0.0013 0.0032
Echinococcus multilocularis tyrosine protein kinase Fyn 0.029 0.0693 0.0689
Onchocerca volvulus 0.0043 0.0062 0.021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0377 0.0914 0.4862
Echinococcus granulosus signal transduction protein lnk realted 0.0033 0.0037 0.0033
Entamoeba histolytica hypothetical protein 0.009 0.0182 0.0954
Echinococcus granulosus neuroglian 0.004 0.0055 0.0051
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0044 0.0064 0.022
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0173 0.0394 0.1395
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0754 0.1875 1
Entamoeba histolytica hypothetical protein 0.0027 0.0022 0.0097
Brugia malayi SRC-1 0.029 0.0693 0.245
Brugia malayi SH2 domain containing protein 0.0033 0.0037 0.0131
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0249 0.0588 0.0584
Schistosoma mansoni apoptosis stimulating of P53 0.0027 0.0022 0.0065
Echinococcus multilocularis lachesin 0.004 0.0055 0.0051
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0032 0.0028
Brugia malayi Immunoglobulin I-set domain containing protein 0.004 0.0055 0.0194
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.001 0.0035
Echinococcus multilocularis tensin 0.0033 0.0037 0.0033
Entamoeba histolytica protein kinase domain containing protein 0.0053 0.0089 0.0453
Brugia malayi SH2 domain containing protein 0.0033 0.0037 0.0131
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0173 0.0394 0.3983
Loa Loa (eye worm) hypothetical protein 0.0383 0.093 0.3288
Loa Loa (eye worm) hypothetical protein 0.0069 0.0128 0.0449
Echinococcus multilocularis high voltage activated calcium channel beta 0.0091 0.0184 0.018
Brugia malayi Immunoglobulin domain containing protein 0.0022 0.001 0.0035
Schistosoma mansoni run and tbc1 domain containing 0.0027 0.0022 0.0065
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0464 0.2458
Loa Loa (eye worm) hypothetical protein 0.0033 0.0037 0.0126
Schistosoma mansoni slit-robo rho gtpase activating protein 0.0027 0.0022 0.0065
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0033 0.0037 0.0033
Brugia malayi SH2 domain containing protein 0.0033 0.0037 0.0131
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0428 0.1044 0.3727
Brugia malayi hypothetical protein 0.0492 0.1209 0.4276
Echinococcus multilocularis nostrin 0.0027 0.0022 0.0018
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0336 0.0809 0.286
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0173 0.0394 0.139
Onchocerca volvulus Putative cortactin 0.0027 0.0022 0.0059
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0064 0.0115 0.0596
Trichomonas vaginalis CMGC family protein kinase 0.0143 0.0318 0.1678
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.003
Leishmania major phosphatidylinositol 3-kinase, putative 0.0365 0.0885 0.2407
Echinococcus granulosus tyrosine protein kinase Src42A 0.0249 0.0588 0.0584
Mycobacterium ulcerans putative regulatory protein 0.002 0.0004 0.0007
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0033 0.0037 0.0126
Schistosoma mansoni aryl hydrocarbon receptor 0.0051 0.0082 0.0282
Onchocerca volvulus LIM and SH3 domain protein homolog 0.0027 0.0022 0.0059
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0428 0.1044 0.1041
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0007 0.001
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0033 0.0037 0.0033
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0058 0.0194
Echinococcus multilocularis fch and double sh3 domains protein 2 0.0027 0.0022 0.0018
Brugia malayi Immunoglobulin I-set domain containing protein 0.004 0.0055 0.0194
Echinococcus granulosus epidermal growth factor receptor kinase 0.0027 0.0022 0.0018
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.009 0.0182 0.064
Echinococcus multilocularis contactin neuroglian septate junction protein 0.004 0.0055 0.0051
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0033 0.0037 0.0033
Echinococcus multilocularis intersectin 2 0.0028 0.0024 0.0021
Echinococcus granulosus tyrosine protein kinase Srms 0.0047 0.0073 0.0069
Brugia malayi hypothetical protein 0.0038 0.0049 0.0172
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0038 0.005 0.0469
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0217 0.0506 0.2682
Echinococcus granulosus protein kinase shaggy 0.0053 0.0089 0.0085
Brugia malayi SH2 domain containing protein 0.0033 0.0037 0.0131
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0022 0.001 0.0006
Schistosoma mansoni cell adhesion molecule 0.004 0.0055 0.0183
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0209 0.1099
Onchocerca volvulus Basement membrane proteoglycan homolog 0.004 0.0055 0.0183
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0114 0.0243 1
Giardia lamblia Hypothetical protein 0.009 0.0182 0.1476
Toxoplasma gondii target of rapamycin (TOR), putative 0.0404 0.0983 1
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0038 0.005 0.0167
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.004 0.0055 0.0183
Onchocerca volvulus 0.0033 0.0037 0.0116
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0031 0.0145
Echinococcus granulosus SHC transforming protein 3 0.0033 0.0037 0.0033
Echinococcus multilocularis tyrosine protein kinase Src64B 0.029 0.0693 0.0689
Loa Loa (eye worm) hypothetical protein 0.0069 0.0128 0.0449
Entamoeba histolytica hypothetical protein 0.0038 0.0049 0.024
Loa Loa (eye worm) hypothetical protein 0.0069 0.0128 0.0449
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0022 0.001 0.0006
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0031 0.0145
Echinococcus multilocularis voltage dependent calcium channel 0.0034 0.0038 0.0034
Echinococcus granulosus defective proboscis extension response 0.0069 0.0128 0.0125
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.1114 0.2796 1
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.005 0.0249
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.029 0.0693 0.0689
Echinococcus multilocularis titin 0.0021 0.0007 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0255 0.0604 0.3205
Schistosoma mansoni signal transduction protein lnk-related 0.0033 0.0037 0.0119
Echinococcus granulosus bloom syndrome protein 0.0022 0.0009 0.0005
Brugia malayi Pre-SET motif family protein 0.0216 0.0503 0.178
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0038 0.005 0.0249
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0047 0.0073 0.037
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.009 0.0182 0.0519
Loa Loa (eye worm) phosphatidylinositol 3 0.0377 0.0914 0.3229
Schistosoma mansoni basigin related 0.0022 0.001 0.0022
Plasmodium vivax SET domain protein, putative 0.0031 0.0032 0.0696
Echinococcus granulosus roundabout 2 0.0109 0.023 0.0227
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0022 0.0051
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.005 0.0249
Schistosoma mansoni hypothetical protein 0.0022 0.001 0.0022
Loa Loa (eye worm) hypothetical protein 0.004 0.0055 0.0189
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0028 0.0024 0.0111
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0064 0.0115 0.0596
Echinococcus granulosus survival motor neuron protein 1 0.0492 0.1209 0.1206
Echinococcus granulosus N chimaerin 0.0033 0.0037 0.0033
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0336 0.0809 0.2863
Echinococcus multilocularis Immunoglobulin 0.0069 0.0128 0.0125
Loa Loa (eye worm) phosphatidylinositol 3 0.009 0.0182 0.064
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0064 0.0115 0.0596
Giardia lamblia GTOR 0.0428 0.1044 0.9879
Echinococcus multilocularis SHC transforming protein 3 0.0033 0.0037 0.0033
Loa Loa (eye worm) phosphofructokinase 0.0114 0.0243 0.0853
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0428 0.1044 0.1041
Brugia malayi hypothetical protein 0.0033 0.0037 0.0131
Brugia malayi Immunoglobulin I-set domain containing protein 0.004 0.0055 0.0194
Brugia malayi Immunoglobulin domain containing protein 0.0022 0.001 0.0035
Echinococcus granulosus titin 0.0021 0.0007 0.0003
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0409 0.0996 0.953
Trichomonas vaginalis PIKK family atypical protein kinase 0.0385 0.0934 0.497
Onchocerca volvulus 0.0246 0.0579 0.2177
Loa Loa (eye worm) hypothetical protein 0.006 0.0106 0.0371
Echinococcus multilocularis roundabout 2 0.004 0.0055 0.0051
Echinococcus multilocularis 0.0033 0.0037 0.0033
Echinococcus granulosus titin 0.0021 0.0007 0.0003
Brugia malayi Immunoglobulin I-set domain containing protein 0.004 0.0055 0.0194
Loa Loa (eye worm) hypothetical protein 0.0033 0.0037 0.0126
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0029 0.0025
Entamoeba histolytica hypothetical protein 0.0027 0.0022 0.0097
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0031 0.0271
Brugia malayi bHLH-PAS transcription factor 0.0038 0.0049 0.0172
Echinococcus granulosus casein kinase ii subunit beta 0.0038 0.005 0.0047
Loa Loa (eye worm) sex muscle abnormal protein 5 0.006 0.0106 0.0371
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.004 0.0055 0.0189
Echinococcus multilocularis lamin 0.0028 0.0024 0.002
Entamoeba histolytica hypothetical protein, conserved 0.0027 0.0022 0.0097
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.004 0.0055 0.0189
Brugia malayi SH2 domain containing protein 0.0047 0.0073 0.0258
Plasmodium falciparum phosphatidylinositol 4-kinase 0.009 0.0182 0.4595
Brugia malayi SH2 domain containing protein 0.0047 0.0073 0.0258
Loa Loa (eye worm) hypothetical protein 0.0492 0.1209 0.4273
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.009 0.0182 0.0179
Echinococcus multilocularis transfer RNA-Lys 0.0038 0.0049 0.0045
Loa Loa (eye worm) phosphatidylinositol 3 0.0988 0.2473 0.8746
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0336 0.0809 0.286
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0115 0.0596
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.03 0.0717 0.6856
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0038 0.005 0.0249
Echinococcus multilocularis Zinc finger, PHD finger 0.0173 0.0394 0.0391
Echinococcus multilocularis Immunoglobulin subtype 0.0022 0.001 0.0006
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.009 0.0182 0.1712
Echinococcus granulosus endophilin A3 0.0027 0.0022 0.0018
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0173 0.0394 1
Schistosoma mansoni shc transforming protein 0.0033 0.0037 0.0119
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0022 0.0051
Schistosoma mansoni eps8-related protein 0.0027 0.0022 0.0065
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.005 0.0249
Echinococcus granulosus SH2 domain containing adapter protein F 0.0033 0.0037 0.0033
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0365 0.0885 0.8468
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.009 0.0182 0.0179
Brugia malayi Pre-SET motif family protein 0.0031 0.0032 0.0112
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.005 0.0249
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0064 0.0115 0.0596
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0028 0.0024 0.0111
Brugia malayi serine/threonine-protein kinase plk-2 0.02 0.0464 0.1641
Trypanosoma brucei protein kinase, putative 0.0053 0.0089 0.081
Schistosoma mansoni hypothetical protein 0.0022 0.001 0.0022
Onchocerca volvulus 0.0047 0.0073 0.0253
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0217 0.0506 0.1462
Brugia malayi Cytochrome P450 family protein 0.002 0.0004 0.0015
Schistosoma mansoni high voltage-activated calcium channel beta subunit 2 0.0091 0.0184 0.0645
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0028 0.0024 0.0087
Echinococcus granulosus geminin 0.0176 0.0401 0.0397
Brugia malayi basement membrane proteoglycan 0.0022 0.001 0.0035
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0024 0.0013 0.004
Entamoeba histolytica protein kinase, putative 0.0037 0.0046 0.0226
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0428 0.1044 0.2843
Echinococcus granulosus peroxidasin 0.004 0.0055 0.0051
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0031 0.0145
Loa Loa (eye worm) TK/FER protein kinase 0.0047 0.0073 0.0253
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.009 0.0182 0.4564
Echinococcus multilocularis Immunoglobulin 0.0069 0.0128 0.0125
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.03 0.0717 0.3813
Schistosoma mansoni hypothetical protein 0.0038 0.0049 0.0161
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.005 0.0249
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.009 0.0182 0.0954
Brugia malayi hypothetical protein 0.0171 0.0388 0.1372
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0022 0.001 0.0006
Echinococcus granulosus roundabout 2 0.004 0.0055 0.0051
Schistosoma mansoni sorting nexin 0.0029 0.0026 0.0079
Echinococcus granulosus casein kinase ii subunit alpha 0.0143 0.0318 0.0314
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0022 0.0097
Loa Loa (eye worm) TK/FER protein kinase 0.0047 0.0073 0.0253
Brugia malayi Src substrate cortactin 0.0027 0.0022 0.0078
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0247 0.0583 0.2058
Loa Loa (eye worm) hypothetical protein 0.0033 0.0037 0.0126
Loa Loa (eye worm) hypothetical protein 0.004 0.0055 0.0189
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0243 0.1276
Loa Loa (eye worm) voltage-dependent calcium channel beta 2a subunit 0.0187 0.0429 0.1514
Echinococcus multilocularis tyrosine kinase 0.0047 0.0073 0.0069
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0064 0.0115 0.0596
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.004 0.0055 0.0051
Echinococcus granulosus SH2 domain containing protein 7 0.0033 0.0037 0.0033
Loa Loa (eye worm) variant SH3 domain-containing protein 0.006 0.0106 0.0371
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0093 0.019 0.0668
Entamoeba histolytica hypothetical protein 0.0027 0.0022 0.0097
Echinococcus granulosus single minded 2 0.0038 0.0049 0.0045
Schistosoma mansoni nephrin related 0.0022 0.001 0.0022
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0074 0.0142 0.0496
Loa Loa (eye worm) hypothetical protein 0.004 0.0055 0.0189
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0024 0.0013 0.004
Brugia malayi Fibronectin type III domain containing protein 0.0069 0.0128 0.0454
Echinococcus granulosus tyrosine protein kinase Src64B 0.029 0.0693 0.0689
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0064 0.0115 0.0596
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.1114 0.2796 0.2793
Schistosoma mansoni sorbin 0.0027 0.0022 0.0065
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0034 0.0038 0.0034
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0263 0.0623 0.062
Onchocerca volvulus 0.0053 0.0089 0.0312
Brugia malayi Immunoglobulin I-set domain containing protein 0.0032 0.0033 0.0118
Schistosoma mansoni protein kinase 0.0143 0.0318 0.1125
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0038 0.005 0.0249
Entamoeba histolytica BAR/SH3 domain containing protein 0.0027 0.0022 0.0097
Schistosoma mansoni phosphatidylinositol 4-kinase 0.009 0.0182 0.064
Loa Loa (eye worm) SH2 domain-containing protein 0.0033 0.0037 0.0126
Mycobacterium ulcerans putative regulatory protein 0.0038 0.0049 0.1861
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0022 0.0097
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.004 0.0055 0.0051
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0031 0.5
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0047 0.0073 0.0069
Schistosoma mansoni peroxidasin 0.0022 0.001 0.0022
Schistosoma mansoni titin 0.0021 0.0007 0.001
Brugia malayi PXA domain containing protein 0.0022 0.0008 0.0027
Echinococcus granulosus tyrosine protein kinase HCK 0.023 0.0539 0.0535
Brugia malayi basement membrane proteoglycan precursor 0.0022 0.001 0.0035
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0064 0.0115 0.1068
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0173 0.0394 1
Schistosoma mansoni kinase 0.0103 0.0216 0.0761
Plasmodium falciparum casein kinase II beta chain 0.0038 0.005 0.1228
Plasmodium falciparum glycogen synthase kinase 3 0.0053 0.0089 0.2203
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0033 0.0037 0.0126
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0064 0.0115 0.0596
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0022 0.0097
Echinococcus multilocularis neuroglian 0.0086 0.0173 0.0169
Schistosoma mansoni 6-phosphofructokinase 0.0114 0.0243 0.0855
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0173 0.0394 0.1137
Loa Loa (eye worm) SH2 domain-containing protein 0.0033 0.0037 0.0126
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0022 0.001 0.0006
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0064 0.0115 0.0596
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0232 0.0545 0.1927
Loa Loa (eye worm) TK/ABL protein kinase 0.0047 0.0073 0.0253
Echinococcus multilocularis 6 phosphofructokinase 0.0114 0.0243 0.0239
Echinococcus granulosus nuclear factor of activated T cells 5 0.0077 0.0149 0.0145
Echinococcus multilocularis casein kinase ii subunit beta 0.0038 0.005 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0428 0.1044 0.556
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0009 0.0028
Entamoeba histolytica casein kinase, putative 0.0143 0.0318 0.1678
Schistosoma mansoni cell adhesion molecule 0.0091 0.0186 0.0651
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0034 0.0038 0.0034
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0069 0.0128 0.0446
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0095 0.0489
Schistosoma mansoni hypothetical protein 0.0027 0.0022 0.0065
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0022 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0409 0.0995 0.5298
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0032 0.0028
Loa Loa (eye worm) phosphatidylinositol 3 0.0428 0.1044 0.3691
Schistosoma mansoni serine/threonine protein kinase 0.0024 0.0013 0.0032
Brugia malayi Variant SH3 domain containing protein 0.0034 0.0039 0.014
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.029 0.0693 0.0689
Trichomonas vaginalis PIKK family atypical protein kinase 0.0428 0.1044 0.556
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0072
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0032 0.0033 0.003
Schistosoma mansoni survival motor neuron protein 0.01 0.0209 0.0735
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0043 0.0064 0.0319
Entamoeba histolytica protein kinase, putative 0.0027 0.0022 0.0097
Brugia malayi M-phase phosphoprotein, mpp8 0.0105 0.0221 0.078
Brugia malayi Tyrosine-protein kinase abl-1 0.0074 0.0142 0.0503
Loa Loa (eye worm) p53BP2 0.0027 0.0022 0.0072
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0053 0.0089 0.023
Brugia malayi hypothetical protein 0.0047 0.0073 0.0258
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0038 0.005 0.0134
Leishmania major phosphatidylinositol kinase, putative 0.009 0.0182 0.0487
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0361 0.0873 0.3088
Schistosoma mansoni nck2/grb4 0.006 0.0106 0.0367
Echinococcus granulosus Immunoglobulin 0.0022 0.001 0.0006
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0022 0.001 0.0022
Echinococcus multilocularis slit robo rho gtpase activating protein 1 0.0027 0.0022 0.0018
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.003
Plasmodium vivax unspecified product 0.0143 0.0318 0.8042
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0064 0.0115 0.0596
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0011
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0033 0.0037 0.0033
Entamoeba histolytica protein kinase, putative 0.0053 0.0089 0.0453
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0754 0.1875 0.5457
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0028 0.0024 0.0021
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.009 0.0182 0.0519
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.009 0.0182 0.064
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0173 0.0394 0.1066
Brugia malayi cytokine inducible SH2-containing protein 5 0.0033 0.0037 0.0131
Loa Loa (eye worm) hypothetical protein 0.0109 0.023 0.081
Loa Loa (eye worm) phosphatidylinositol 3 0.009 0.0182 0.064
Loa Loa (eye worm) hypothetical protein 0.0052 0.0085 0.0294
Echinococcus granulosus src region 0.0027 0.0022 0.0018
Schistosoma mansoni voltage-gated cation channel 0.0034 0.0038 0.0123
Brugia malayi Immunoglobulin I-set domain containing protein 0.004 0.0055 0.0194
Loa Loa (eye worm) protein kinase C and casein kinase substrate in neurons protein 2 0.0027 0.0022 0.0072
Schistosoma mansoni Dab2-interacting protein-like 0.0027 0.0022 0.0065
Brugia malayi Csnk2b protein 0.0038 0.005 0.0178
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0034 0.0038 0.0123
Brugia malayi Variant SH3 domain containing protein 0.0027 0.0022 0.0078
Brugia malayi Myosin tail family protein 0.0027 0.0022 0.0078
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0754 0.1875 0.6635
Brugia malayi hypoxia-induced factor 1 0.0157 0.0354 0.1253
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0217 0.0506 0.1789
Echinococcus granulosus expressed protein 0.0027 0.0022 0.0018
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0064 0.0115 0.0596
Loa Loa (eye worm) CAMK protein kinase 0.0021 0.0007 0.0018
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0428 0.1044 0.2843
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.009 0.0182 0.0954
Loa Loa (eye worm) SH2 domain-containing protein 0.0033 0.0037 0.0126
Trichomonas vaginalis PIKK family atypical protein kinase 0.0365 0.0885 0.4709
Loa Loa (eye worm) RGS-3 protein 0.002 0.0004 0.0008
Echinococcus multilocularis tyrosine protein kinase Fyn 0.029 0.0693 0.0689
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0173 0.0394 0.1398
Onchocerca volvulus 0.0047 0.0073 0.0253
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0173 0.0394 0.2086
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0173 0.0394 0.2086
Loa Loa (eye worm) STAT protein 0.0033 0.0037 0.0126
Entamoeba histolytica hypothetical protein 0.0027 0.0022 0.0097
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0022 0.001 0.0022
Echinococcus granulosus growth factor receptor bound protein 2 0.006 0.0106 0.0103
Plasmodium falciparum casein kinase 2, alpha subunit 0.0143 0.0318 0.8053
Trichomonas vaginalis conserved hypothetical protein 0.0239 0.0562 0.2981
Brugia malayi Variant SH3 domain containing protein 0.0027 0.0022 0.0078
Schistosoma mansoni lamin 0.0028 0.0024 0.0072
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0072
Brugia malayi intracellular kinase 0.0053 0.0089 0.0313
Trichomonas vaginalis PIKK family atypical protein kinase 0.0404 0.0983 0.5232
Giardia lamblia Casein kinase II beta chain 0.0038 0.005 0.0189
Leishmania major ATP-dependent phosphofructokinase 0.0114 0.0243 0.0651
Loa Loa (eye worm) hypothetical protein 0.0028 0.0024 0.0081
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0033 0.0037 0.0033
Loa Loa (eye worm) phosphatidylinositol 3 0.009 0.0182 0.064
Loa Loa (eye worm) TK protein kinase 0.0032 0.0033 0.0113
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0024 0.008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0404 0.0983 0.5232
Brugia malayi Protein kinase domain containing protein 0.0336 0.0809 0.2863
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0089 0.0453
Loa Loa (eye worm) hypothetical protein 0.004 0.0055 0.0189
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.03 0.0717 0.3813
Echinococcus multilocularis tensin 0.0033 0.0037 0.0033
Loa Loa (eye worm) gastrulation defective protein 1 0.0136 0.03 0.1058
Brugia malayi Variant SH3 domain containing protein 0.006 0.0106 0.0376
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0118 0.0255 0.0251
Brugia malayi phosphofructokinase 0.0114 0.0243 0.0858
Schistosoma mansoni cellular tumor antigen P53 0.0052 0.0085 0.0289
Brugia malayi Immunoglobulin I-set domain containing protein 0.0022 0.001 0.0035
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0033 0.0037 0.0033
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.03 0.0717 0.208
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.002 0.0004 0.0007
Onchocerca volvulus 0.0105 0.0221 0.0813
Trichomonas vaginalis casein kinase II beta chain, putative 0.0038 0.005 0.0249
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.029 0.0693 0.0689
Echinococcus granulosus c src tyrosine kinase 0.0074 0.0142 0.0139
Toxoplasma gondii hypothetical protein 0.0056 0.0095 0.0929
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0754 0.1875 1
Echinococcus multilocularis tyrosine protein kinase Srms 0.0263 0.0623 0.062
Onchocerca volvulus 0.0027 0.0022 0.0059
Brugia malayi Variant SH3 domain containing protein 0.0027 0.0022 0.0078
Trichomonas vaginalis CAMK family protein kinase 0.02 0.0464 0.2458
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0627 0.1552 0.8273
Trichomonas vaginalis PIKK family atypical protein kinase 0.0404 0.0983 0.5232
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0428 0.1044 0.3695

Activities

Activity type Activity value Assay description Source Reference
MIC (functional) 0 ug ml-1 Antibacterial activity of the compound was determined against Escherichia coli at ChEMBL. 14684343
MIC (functional) = 8 ug ml-1 Antibacterial activity of the compound was determined against Staphylococcus aureus; Range is 2-8 ChEMBL. 14684343
MIC (functional) = 16 ug ml-1 Antibacterial activity of the compound was determined against Enterococcus faecalis; Range is 8-16 ChEMBL. 14684343

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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