Detailed information for compound 550457

Basic information

Technical information
  • TDR Targets ID: 550457
  • Name: 1,3,5-trichloro-2-[chloro-(2,4,6-trichlorophe noxy)phosphoryl]oxy-benzene
  • MW: 475.303 | Formula: C12H4Cl7O3P
  • H donors: 0 H acceptors: 1 LogP: 7.65 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1cc(Cl)cc(c1OP(=O)(Oc1c(Cl)cc(cc1Cl)Cl)Cl)Cl
  • InChi: 1S/C12H4Cl7O3P/c13-5-1-7(15)11(8(16)2-5)21-23(19,20)22-12-9(17)3-6(14)4-10(12)18/h1-4H
  • InChiKey: DXKZQNUSKZOLTC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1,3,5-trichloro-2-[chloro-(2,4,6-trichlorophenoxy)phosphoryl]oxybenzene
  • bis(2,4,6-trichlorophenyl) phosphorochloridate
  • 17725-11-0
  • BTPPC
  • Phosphorochloridic acid, bis(2,4,6-trichlorophenyl) ester

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Cathepsin L-like cysteine proteinase 0.0023 0.0058 0.0153
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0046 0.1773
Onchocerca volvulus 0.0023 0.0058 0.0849
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.001 0.0011 0.0415
Loa Loa (eye worm) hypothetical protein 0.0266 0.0911 0.241
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0157 0.1993
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0182 0.2303
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.008 0.0258 0.0683
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0138 0.0462 0.1222
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0153
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0103 0.0273
Loa Loa (eye worm) hypothetical protein 0.0036 0.0103 0.0273
Loa Loa (eye worm) Smad1 0.0009 0.0006 0.0015
Loa Loa (eye worm) TAR-binding protein 0.0067 0.021 0.0556
Echinococcus granulosus bloom syndrome protein 0.002 0.0046 0.0046
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0102 0.0102
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.001 0.0011 0.0136
Leishmania major heat shock protein 83-1 0.0031 0.0086 0.0228
Onchocerca volvulus Cathepsin L homolog 0.0035 0.0098 0.1444
Leishmania major cathepsin L-like protease 0.0133 0.0442 0.117
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0039 0.376
Mycobacterium ulcerans hypothetical protein 0.0036 0.0103 0.3998
Echinococcus granulosus cathepsin L 0.0018 0.0039 0.0039
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0022 0.0051 0.1987
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.001 0.0011 0.0136
Brugia malayi Cathepsin L-like precursor 0.0035 0.0098 0.026
Leishmania major cytochrome p450-like protein 0.001 0.0011 0.0028
Echinococcus multilocularis Smad4 0.0009 0.0006 0.0006
Entamoeba histolytica cysteine protease, putative 0.0018 0.0039 0.1666
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.001 0.0011 0.0415
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0035 0.0098 0.9507
Schistosoma mansoni hypothetical protein 0.0007 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0016 0.0043
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0022 0.0051 0.1987
Loa Loa (eye worm) MH1 domain-containing protein 0.0009 0.0006 0.0015
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0028 0.0073 0.283
Schistosoma mansoni hypothetical protein 0.0035 0.01 0.01
Leishmania major cathepsin L-like protease 0.0035 0.0098 0.026
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.002 0.0046 0.0122
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.001 0.0011 0.0415
Trichomonas vaginalis DNA helicase recq1, putative 0.002 0.0046 0.4436
Trypanosoma cruzi cysteine peptidase, putative 0.0133 0.0442 0.117
Trichomonas vaginalis heat shock protein, putative 0.0019 0.0043 0.4212
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.002 0.0046 0.0046
Loa Loa (eye worm) CXXC zinc finger family protein 0.0013 0.0022 0.0059
Echinococcus multilocularis smad 0.0009 0.0006 0.0006
Echinococcus granulosus TGF beta signal transducer SmadC 0.0009 0.0006 0.0006
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.004 0.4602
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.008 0.0258 1
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.002 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.006
Brugia malayi cytochrome P450 0.001 0.0011 0.0028
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0102 0.027
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0007 0.0001 0.0003
Trypanosoma cruzi cysteine protease, putative 0.0018 0.0039 0.0103
Loa Loa (eye worm) hypothetical protein 0.038 0.131 0.3467
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0046 0.0121
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.001 0.0011 0.0415
Mycobacterium tuberculosis Cyclopropane-fatty-acyl-phospholipid synthase 1 CmaA1 (cyclopropane fatty acid synthase) (CFA synthase) (cyclopropane mycolic ac 0.0039 0.0112 0.1412
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.004 0.0105
Brugia malayi hypothetical protein 0.0218 0.0741 0.1962
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0023 0.2205
Brugia malayi hypothetical protein 0.0035 0.01 0.0263
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0023 0.2205
Onchocerca volvulus 0.0036 0.0103 0.1518
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0024 0.0058 0.0154
Loa Loa (eye worm) hypothetical protein 0.0055 0.0168 0.0445
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.002 0.0046 0.0122
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0073 0.0233 0.9023
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.004 0.1702
Loa Loa (eye worm) ATP-dependent DNA helicase 0.002 0.0046 0.0121
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0232 0.079 1
Brugia malayi Cathepsin L-like precursor 0.0035 0.0098 0.026
Echinococcus granulosus ubiquitin specific protease 41 0.002 0.0046 0.0046
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.002 0.0046 0.446
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0053 0.0161 0.6232
Loa Loa (eye worm) hypothetical protein 0.0036 0.0103 0.0273
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0018 0.004 0.1568
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.001 0.0011 0.0136
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.004 0.384
Leishmania major heat shock protein 83-1 0.0031 0.0086 0.0228
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0024 0.0058 0.0154
Echinococcus granulosus peptidase Clp S14 family 0.0053 0.0161 0.0161
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0012 0.0016 0.0043
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.001 0.0011 0.0136
Brugia malayi Cathepsin L-like precursor 0.0035 0.0098 0.026
Trypanosoma cruzi cysteine peptidase, putative 0.0035 0.0098 0.026
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0035 0.0098 0.0098
Brugia malayi CXXC zinc finger family protein 0.0013 0.0022 0.0059
Plasmodium vivax acyl-CoA synthetase, putative 0.0055 0.0168 0.6505
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0046 0.4436
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0022 0.0051 0.1987
Plasmodium vivax vivapain-1 0.0018 0.0039 0.1503
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0023 0.2205
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0133 0.0442 0.117
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0051 0.0136
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0022 0.0051 0.1987
Onchocerca volvulus 0.0035 0.0098 0.1444
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0013 0.0023 0.006
Trypanosoma cruzi sterol 24-c-methyltransferase, putative 0.078 0.2713 0.7182
Loa Loa (eye worm) hypothetical protein 0.0012 0.0016 0.0043
Loa Loa (eye worm) hypothetical protein 0.0201 0.068 0.18
Leishmania major heat shock protein 83-1 0.0031 0.0086 0.0228
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.002 0.0046 0.0122
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0051 0.0649
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0182 0.0182
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0039 0.0103
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.001 0.0391
Loa Loa (eye worm) hypothetical protein 0.0016 0.0031 0.0082
Brugia malayi Cytochrome P450 family protein 0.0018 0.004 0.0107
Trichomonas vaginalis maltase-glucoamylase, putative 0.0013 0.0023 0.2205
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.002 0.0046 0.0046
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0182 0.0182
Plasmodium vivax heat shock protein 90, putative 0.0013 0.0021 0.0814
Onchocerca volvulus 0.0022 0.0051 0.0754
Trichomonas vaginalis CMGC family protein kinase 0.0024 0.0058 0.5641
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.004 0.0105
Trypanosoma brucei glucosidase, putative 0.0036 0.0102 0.027
Trypanosoma brucei Heat shock protein 83, putative 0.0031 0.0086 0.0228
Trypanosoma brucei heat shock protein 84, putative 0.0013 0.0021 0.0056
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0051 0.1987
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0012 0.0016 0.0043
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0182 0.7048
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0028 0.0073 0.2497
Trichomonas vaginalis endoplasmin, putative 0.0019 0.0043 0.4212
Plasmodium vivax vivapain-3 0.0018 0.0039 0.1503
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0023 0.2205
Echinococcus multilocularis microtubule associated protein 2 0.2857 1 1
Mycobacterium tuberculosis Probable cyclopropane-fatty-acyl-phospholipid synthase UfaA1 (cyclopropane fatty acid synthase) (CFA synthase) 0.0039 0.0112 0.1412
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.001 0.0011 0.0415
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.001 0.0011 0.0415
Trypanosoma cruzi heat shock protein 85, putative 0.0031 0.0086 0.0228
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.001 0.0011 0.0136
Leishmania major sterol 24-c-methyltransferase, putative 0.078 0.2713 0.7182
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0051 0.0649
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0103 0.0103
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0103 0.3998
Trypanosoma cruzi sterol 24-c-methyltransferase, putative 0.0039 0.0112 0.0295
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.004 0.0105
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0098 0.9507
Mycobacterium tuberculosis Conserved protein 0.0036 0.0103 0.1307
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.004 0.0105
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0102 0.4375
Schistosoma mansoni heat shock protein 0.0013 0.0021 0.0021
Leishmania major sterol 24-c-methyltransferase, putative 0.078 0.2713 0.7182
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0011 0.0444
Leishmania major 4-coumarate:coa ligase-like protein 0.0073 0.0233 0.0617
Leishmania major 4-coumarate:coa ligase-like protein 0.0073 0.0233 0.0617
Leishmania major heat shock protein 83-1 0.0031 0.0086 0.0228
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.004 0.1535
Loa Loa (eye worm) cysteine protease 0.0035 0.0098 0.026
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0133 0.0442 0.117
Loa Loa (eye worm) hypothetical protein 0.0073 0.0233 0.0617
Trypanosoma cruzi cysteine proteinase, putative 0.0018 0.0039 0.0103
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0103 0.3998
Leishmania major cathepsin L-like protease 0.0035 0.0098 0.026
Brugia malayi Probable ClpP-like protease 0.008 0.0258 0.0683
Schistosoma mansoni ap endonuclease 0.0018 0.004 0.004
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0025 0.0064 0.0064
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0102 0.9873
Trichomonas vaginalis antibiotic synthetase, putative 0.0022 0.0051 0.4968
Entamoeba histolytica hypothetical protein 0.0035 0.01 0.4271
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0098 0.9507
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0182 0.7048
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0094 0.0305 0.0806
Trypanosoma brucei heat shock protein, putative 0.0031 0.0086 0.0228
Mycobacterium leprae Conserved hypothetical protein 0.001 0.0011 0.0415
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0102 0.9873
Loa Loa (eye worm) cytochrome P450 0.001 0.0011 0.0028
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0051 0.0136
Schistosoma mansoni endoplasmin 0.0031 0.0086 0.0086
Mycobacterium ulcerans methoxy mycolic acid synthase 2, MmaA2 0.0039 0.0112 0.432
Echinococcus granulosus survival motor neuron protein 1 0.0218 0.0741 0.0741
Leishmania major cathepsin L-like protease 0.0035 0.0098 0.026
Trypanosoma cruzi heat shock protein 90, putative 0.0031 0.0086 0.0228
Leishmania major heat shock protein 83-1 0.0031 0.0086 0.0228
Onchocerca volvulus Cathepsin L homolog 0.0035 0.0098 0.1444
Echinococcus multilocularis dnaJ subfamily B 0.0189 0.0638 0.0638
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0103 0.1307
Trypanosoma brucei cytochrome P450, putative 0.0018 0.004 0.0107
Leishmania major heat shock protein 83-1 0.0031 0.0086 0.0228
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.008 0.0258 1
Brugia malayi MH2 domain containing protein 0.0009 0.0006 0.0015
Trypanosoma cruzi cruzipain precursor, putative 0.0012 0.0016 0.0043
Leishmania major acetyl-CoA synthetase, putative 0.0022 0.0051 0.0136
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0078 0.0249 0.0249
Echinococcus granulosus heat shock protein 90 0.0025 0.0064 0.0064
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0103 0.0103
Trypanosoma cruzi cysteine peptidase, putative 0.0133 0.0442 0.117
Schistosoma mansoni Smad4 0.0009 0.0006 0.0006
Brugia malayi RNA binding protein 0.0067 0.021 0.0556
Schistosoma mansoni hypothetical protein 0.0142 0.0473 0.0473
Mycobacterium ulcerans heat shock protein 90 0.0025 0.0064 0.2466
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.001 0.0011 0.0415
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.0098 0.0098
Plasmodium vivax acetyl-CoA synthetase, putative 0.0022 0.0051 0.1987
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0133 0.0442 0.117
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0013 0.0023 0.0977
Trypanosoma cruzi Emopamil binding protein, putative 0.0138 0.0462 0.1222
Loa Loa (eye worm) hypothetical protein 0.0055 0.0168 0.0445
Entamoeba histolytica hypothetical protein 0.0035 0.01 0.4271
Loa Loa (eye worm) hypothetical protein 0.0007 0.0001 0.0003
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0022 0.0051 0.0649
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.001 0.0011 0.0415
Brugia malayi Papain family cysteine protease containing protein 0.0035 0.0098 0.026
Mycobacterium ulcerans hypothetical protein 0.0073 0.0233 0.9023
Trypanosoma cruzi cysteine proteinase, putative 0.0018 0.0039 0.0103
Plasmodium vivax endoplasmin, putative 0.0031 0.0086 0.3337
Leishmania major heat shock protein 83-1 0.0031 0.0086 0.0228
Toxoplasma gondii histone lysine methyltransferase SET1 0.0025 0.0064 0.2472
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.002 0.0046 0.1773
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0022 0.0051 0.1987
Schistosoma mansoni tar DNA-binding protein 0.0067 0.021 0.021
Loa Loa (eye worm) RNA binding protein 0.0067 0.021 0.0556
Schistosoma mansoni tar DNA-binding protein 0.0067 0.021 0.021
Toxoplasma gondii cytochrome p450 superfamily protein 0.001 0.0011 0.0415
Brugia malayi small heat shock protein 0.0266 0.0911 0.241
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0022 0.0051 0.0649
Brugia malayi beta-lactamase family protein 0.0036 0.0103 0.0273
Schistosoma mansoni peptidase Clp (S14 family) 0.008 0.0258 0.0258
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0103 1
Schistosoma mansoni blooms syndrome DNA helicase 0.001 0.001 0.001
Brugia malayi TAR-binding protein 0.0067 0.021 0.0556
Plasmodium vivax heat shock protein, putative 0.0013 0.0021 0.0814
Giardia lamblia Heat shock protein HSP 90-alpha 0.0025 0.0064 0.7391
Entamoeba histolytica heat shock protein 90, putative 0.0031 0.0086 0.3698
Entamoeba histolytica recQ family helicase, putative 0.002 0.0046 0.1966
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0039 0.0112 0.0112
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.004 0.004
Plasmodium vivax vivapain-2 0.0035 0.0098 0.3801
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0046 0.0121
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0133 0.0442 0.117
Entamoeba histolytica cysteine proteinase 2 0.0018 0.0039 0.1666
Schistosoma mansoni tar DNA-binding protein 0.0067 0.021 0.021
Trypanosoma brucei protein kinase, putative 0.0024 0.0058 0.0154
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0098 0.9507
Plasmodium vivax unspecified product 0.0018 0.0039 0.1503
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0022 0.0051 0.1987
Mycobacterium ulcerans mycolic acid synthase PcaA 0.0039 0.0112 0.432
Leishmania major heat shock protein 83-1 0.0031 0.0086 0.0228
Echinococcus granulosus cathepsin l1 0.0035 0.0098 0.0098
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.004 0.1142
Mycobacterium tuberculosis Mycolic acid synthase PcaA (cyclopropane synthase) 0.0039 0.0112 0.1412
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0098 0.9507
Onchocerca volvulus 0.0035 0.0098 0.1444
Entamoeba histolytica cysteine protease, putative 0.0035 0.0098 0.4213
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.001 0.0011 0.0136
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0098 0.9507
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.002 0.0046 0.5344
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0022 0.0051 0.0051
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0098 0.9507
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0039 0.0103
Brugia malayi Endoplasmin precursor 0.0031 0.0086 0.0228
Leishmania major cathepsin L-like protease 0.0035 0.0098 0.026
Loa Loa (eye worm) RecQ helicase 0.002 0.0046 0.0121
Loa Loa (eye worm) hypothetical protein 0.1084 0.3778 1
Loa Loa (eye worm) ctsf protein 0.0035 0.0098 0.026
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0051 0.0136
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0051 0.0649
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0102 0.9873
Entamoeba histolytica cysteine proteinase 1, putative 0.0018 0.0039 0.1666
Schistosoma mansoni cytochrome P450 0.001 0.0011 0.0011
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0103 0.1307
Brugia malayi Latrophilin receptor protein 2 0.0007 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0218 0.0741 0.1962
Echinococcus granulosus ATP dependent DNA helicase Q5 0.002 0.0046 0.0046
Mycobacterium ulcerans acyl-CoA synthetase 0.0073 0.0233 0.9023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0098 0.9507
Schistosoma mansoni alpha glucosidase 0.0036 0.0102 0.0102
Echinococcus granulosus lysosomal alpha glucosidase 0.0162 0.0544 0.0544
Plasmodium falciparum heat shock protein 90, putative 0.0013 0.0021 0.0814
Schistosoma mansoni hypothetical protein 0.0016 0.0031 0.0031
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0103 0.1307
Loa Loa (eye worm) hypothetical protein 0.0039 0.0112 0.0295
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0157 0.1993
Onchocerca volvulus 0.0035 0.0098 0.1444
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.008 0.0258 1
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0162 0.0544 0.1441
Echinococcus multilocularis GPCR, family 2 0.0007 0.0001 0.0001
Onchocerca volvulus 0.0035 0.0098 0.1444
Brugia malayi S-adenosyl-methionine cycloartenol-C24-methyltransferase 0.038 0.131 0.3467
Leishmania major heat shock protein 83-1 0.0031 0.0086 0.0228
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0024 0.0058 0.0154
Loa Loa (eye worm) CYP4Cod1 0.0018 0.004 0.0107
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0103 0.0273
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0051 0.0136
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0039 0.376
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0098 0.9507
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.001 0.0011 0.0136
Entamoeba histolytica cysteine protease, putative 0.0018 0.0039 0.1666
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0053 0.0161 0.2036
Trypanosoma brucei sterol 24-c-methyltransferase, putative 0.0407 0.1404 0.3715
Echinococcus multilocularis mitogen activated protein kinase 3 0.0024 0.0058 0.0058
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0103 0.0273
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.001 0.0011 0.0415
Echinococcus multilocularis peptidase Clp (S14 family) 0.0053 0.0161 0.0161
Loa Loa (eye worm) hypothetical protein 0.0038 0.0108 0.0286
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0073 0.0233 0.2949
Mycobacterium tuberculosis Possible mycolic acid synthase UmaA 0.0039 0.0112 0.1412
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0103 0.3998
Loa Loa (eye worm) fibroinase 0.0035 0.0098 0.026
Entamoeba histolytica hypothetical protein 0.0035 0.01 0.4271
Brugia malayi AMP-binding enzyme family protein 0.0073 0.0233 0.0617
Brugia malayi Calcitonin receptor-like protein seb-1 0.0023 0.0056 0.0149
Echinococcus granulosus cathepsin L cysteine protease 0.0018 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0055 0.0168 0.0445
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0098 0.9507
Mycobacterium tuberculosis Methoxy mycolic acid synthase 4 MmaA4 (methyl mycolic acid synthase 4) (MMA4) (hydroxy mycolic acid synthase) 0.0039 0.0112 0.1412
Echinococcus granulosus cathepsin l cysteine peptidase 0.0035 0.0098 0.0098
Mycobacterium tuberculosis Conserved protein 0.0036 0.0103 0.1307
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0051 0.0136
Toxoplasma gondii heat shock protein 90, putative 0.0031 0.0086 0.3337
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0098 0.9507
Loa Loa (eye worm) hypothetical protein 0.002 0.0046 0.0122
Loa Loa (eye worm) beta-lactamase 0.0036 0.0103 0.0273
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.001 0.0011 0.0415
Echinococcus granulosus tar DNA binding protein 0.0067 0.021 0.021
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0073 0.0233 0.9023
Onchocerca volvulus 0.0201 0.068 1
Mycobacterium ulcerans methoxy mycolic acid synthase 4, MmaA4 0.0039 0.0112 0.432
Echinococcus multilocularis mitogen activated protein kinase 0.0024 0.0058 0.0058
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0157 0.1993
Brugia malayi Bloom's syndrome protein homolog 0.002 0.0046 0.0121
Schistosoma mansoni acetyl-CoA synthetase 0.0022 0.0051 0.0051
Leishmania major cytochrome p450-like protein 0.0018 0.004 0.0107
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0022 0.0051 0.0136
Echinococcus granulosus mitogen activated protein kinase 3 0.0024 0.0058 0.0058
Mycobacterium tuberculosis Methoxy mycolic acid synthase 2 MmaA2 (methyl mycolic acid synthase 2) (MMA2) (hydroxy mycolic acid synthase) 0.0039 0.0112 0.1412
Leishmania major heat shock protein 83-1 0.0031 0.0086 0.0228
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0039 0.0103
Schistosoma mansoni heat shock protein 0.0031 0.0086 0.0086
Trichomonas vaginalis esterase, putative 0.0036 0.0103 1
Schistosoma mansoni smad1 5 8 and 0.0009 0.0006 0.0006
Plasmodium falciparum heat shock protein 90 0.0031 0.0086 0.3337
Leishmania major cathepsin L-like protease 0.0035 0.0098 0.026
Schistosoma mansoni blooms syndrome DNA helicase 0.001 0.0011 0.0011
Brugia malayi bZIP transcription factor family protein 0.0039 0.0112 0.0296
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0058 0.5588
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0025 0.0064 0.0806
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0103 0.3998
Onchocerca volvulus 0.0094 0.0305 0.448
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.004 0.1535
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0009 0.0006 0.0006
Entamoeba histolytica cysteine protease, putative 0.0018 0.0039 0.1666
Entamoeba histolytica cysteine protease, putative 0.0018 0.0039 0.1666
Loa Loa (eye worm) hypothetical protein 0.002 0.0046 0.0121
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0073 0.0233 0.9023
Mycobacterium leprae putative cytochrome p450 0.001 0.0011 0.0415
Entamoeba histolytica cysteine protease, putative 0.0018 0.0039 0.1666
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0039 0.1666
Onchocerca volvulus 0.0022 0.0051 0.0754
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.004 0.0105
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.001 0.0011 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0098 0.9507
Plasmodium falciparum cysteine proteinase falcipain 3 0.0035 0.0098 0.3801
Loa Loa (eye worm) hypothetical protein 0.0036 0.0103 0.0273
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0103 0.0273
Plasmodium falciparum cysteine proteinase falcipain 1 0.0018 0.0039 0.1503
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.001 0.0011 0.0136
Loa Loa (eye worm) hypothetical protein 0.0022 0.0051 0.0136
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0133 0.0442 0.117
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0024 0.0058 0.0154
Schistosoma mansoni hypothetical protein 0.0031 0.0086 0.0086
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0044 0.0132 0.0349
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0102 0.0102
Loa Loa (eye worm) MH2 domain-containing protein 0.0125 0.0415 0.1098
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.001 0.0011 0.0415
Brugia malayi cathepsin F-like cysteine proteinase 0.0012 0.0016 0.0043
Schistosoma mansoni survival motor neuron protein 0.0044 0.0132 0.0132
Entamoeba histolytica cysteine protease, putative 0.0018 0.0039 0.1666
Mycobacterium tuberculosis Possible fatty acid synthase 0.0039 0.0112 0.1412
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.001 0.0011 0.0415
Trypanosoma cruzi sterol 24-c-methyltransferase, putative 0.078 0.2713 0.7182
Schistosoma mansoni hypothetical protein 0.0189 0.0638 0.0638
Mycobacterium tuberculosis Cyclopropane-fatty-acyl-phospholipid synthase 2 CmaA2 (cyclopropane fatty acid synthase) (CFA synthase) (cyclopropane mycolic ac 0.0039 0.0112 0.1412
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0102 0.027
Schistosoma mansoni alpha-glucosidase 0.0139 0.0465 0.0465
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0039 0.0103
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0133 0.0442 0.117
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0133 0.0442 0.117
Mycobacterium ulcerans methoxy mycolic acid synthase 3, MmaA3 0.0039 0.0112 0.432
Echinococcus granulosus heat shock protein 90 0.0031 0.0086 0.0086
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0102 0.9873
Leishmania major heat shock protein, putative 0.0013 0.0021 0.0056
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0022 0.0051 0.0649
Echinococcus granulosus mitogen activated protein kinase 0.0024 0.0058 0.0058
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0133 0.0442 0.117
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0051 0.1987
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0103 0.0103
Trypanosoma cruzi heat shock protein, putative 0.0013 0.0021 0.0056
Treponema pallidum heat shock protein 90 0.0025 0.0064 0.2116
Brugia malayi Hint module family protein 0.0053 0.0161 0.0426
Echinococcus multilocularis tumor protein p63 0.1371 0.4787 0.4787
Brugia malayi MH1 domain containing protein 0.0009 0.0006 0.0015
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.001 0.0011 0.0415
Echinococcus granulosus jun protein 0.0039 0.0112 0.0112
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0022 0.0051 0.0136
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0182 0.0482
Toxoplasma gondii Hsp90 domain-containing protein 0.0013 0.0021 0.0814
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.004 0.384
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0051 0.1987
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0153
Mycobacterium ulcerans beta-lactamase 0.0036 0.0103 0.3998
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0102 0.9873
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.008 0.0258 0.0258
Trypanosoma brucei heat shock protein, putative 0.0031 0.0086 0.0228
Trichomonas vaginalis heat shock protein, putative 0.0013 0.0021 0.2035
Echinococcus granulosus cathepsin l1 0.0023 0.0058 0.0058
Brugia malayi Smad1 0.0009 0.0006 0.0015
Trypanosoma cruzi cytochrome P450, putative 0.0018 0.004 0.0107
Leishmania major cysteine peptidase A (CPA) 0.0035 0.0098 0.026
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0028 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0036 0.0103 0.0273
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0024 0.0058 0.0154
Brugia malayi MH2 domain containing protein 0.0125 0.0415 0.1098
Loa Loa (eye worm) oxidoreductase 0.0022 0.0051 0.0136
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.001 0.0011 0.0136
Loa Loa (eye worm) hypothetical protein 0.0053 0.0161 0.0426
Onchocerca volvulus 0.0022 0.0051 0.0754
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.008 0.0258 1
Trypanosoma cruzi cysteine peptidase, putative 0.0012 0.0016 0.0043
Loa Loa (eye worm) hypothetical protein 0.0094 0.0305 0.0806
Schistosoma mansoni tar DNA-binding protein 0.0067 0.021 0.021
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0098 0.9507
Onchocerca volvulus 0.0022 0.0051 0.0754
Echinococcus multilocularis ubiquitin specific protease 41 0.002 0.0046 0.0046
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0073 0.0233 0.9023
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0035 0.0098 0.026
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0046 0.0121
Trypanosoma cruzi cruzipain precursor, putative 0.0133 0.0442 0.117
Brugia malayi Cytochrome P450 family protein 0.0027 0.007 0.0184
Loa Loa (eye worm) hypothetical protein 0.0055 0.0168 0.0445
Schistosoma mansoni ap endonuclease 0.0018 0.004 0.004
Mycobacterium ulcerans acyl-CoA synthetase 0.0073 0.0233 0.9023
Onchocerca volvulus 0.0138 0.0462 0.6791
Trypanosoma brucei heat shock protein, putative 0.0031 0.0086 0.0228
Leishmania major heat shock protein 83-1 0.0031 0.0086 0.0228
Leishmania major heat shock protein 83-1 0.0031 0.0086 0.0228
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0073 0.0233 0.9023
Leishmania major heat shock protein 83-1 0.0031 0.0086 0.0228
Schistosoma mansoni endoplasmin 0.0031 0.0086 0.0086
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0102 0.3948
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.001 0.0011 0.0136
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0035 0.0098 0.026
Schistosoma mansoni hypothetical protein 0.0044 0.0132 0.0132
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.008 0.0258 1
Echinococcus multilocularis cathepsin L cysteine protease 0.0035 0.0098 0.0098
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0022 0.0051 0.0136
Schistosoma mansoni jun-related protein 0.0031 0.0086 0.0086
Mycobacterium ulcerans methoxy mycolic acid synthase 5 MmaA5 0.0039 0.0112 0.432
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0098 0.9507
Trypanosoma brucei heat shock protein, putative 0.0031 0.0086 0.0228
Entamoeba histolytica cysteine protease, putative 0.0018 0.0039 0.1666
Trypanosoma brucei glycosyl hydrolase-like protein 0.0013 0.0023 0.006
Trypanosoma cruzi heat shock protein 90, putative 0.0019 0.0041 0.0108
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0022 0.0051 0.1987
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.001 0.0011 0.0415
Schistosoma mansoni cpg binding protein 0.0013 0.0022 0.0022
Loa Loa (eye worm) endoplasmin 0.0031 0.0086 0.0228
Loa Loa (eye worm) hypothetical protein 0.0055 0.0168 0.0445
Schistosoma mansoni DNA helicase recq1 0.002 0.0046 0.0046
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0019 0.0041 0.0516
Entamoeba histolytica cysteine protease, putative 0.0018 0.0039 0.1666
Leishmania major heat shock protein 83-1 0.0031 0.0086 0.0228
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0051 0.0136
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0051 0.0136
Brugia malayi Cathepsin L-like precursor 0.0023 0.0058 0.0153
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0035 0.0098 0.9507
Entamoeba histolytica acyl-coA synthetase, putative 0.0073 0.0233 1
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0182 0.7048
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0022 0.0051 0.0136
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0098 0.9507
Echinococcus multilocularis survival motor neuron protein 1 0.0218 0.0741 0.0741
Mycobacterium tuberculosis Methoxy mycolic acid synthase 1 MmaA1 (methyl mycolic acid synthase 1) (MMA1) (hydroxy mycolic acid synthase) 0.0039 0.0112 0.1412
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0102 0.9873
Leishmania major hypothetical protein, conserved 0.0036 0.0103 0.0273
Echinococcus multilocularis mothers against decapentaplegic 5 0.0009 0.0006 0.0006
Plasmodium vivax heat shock protein 86, putative 0.0031 0.0086 0.3337
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0046 0.1773
Onchocerca volvulus 0.0044 0.0132 0.194
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0073 0.0233 0.2949
Giardia lamblia Sgs1 DNA helicase, putative 0.002 0.0046 0.5315
Schistosoma mansoni cpg binding protein 0.0014 0.0025 0.0025
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0024 0.0058 0.0154
Echinococcus granulosus heat shock protein 0.0031 0.0086 0.0086
Trypanosoma cruzi cysteine peptidase, putative 0.0133 0.0442 0.117
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0182 0.0182
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0022 0.0051 0.1987
Brugia malayi cathepsin L-like precursor 0.0023 0.0058 0.0153
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.001 0.0011 0.0415
Echinococcus multilocularis lysosomal alpha glucosidase 0.0162 0.0544 0.0544
Loa Loa (eye worm) heat shock protein 90 0.0031 0.0086 0.0228
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0098 0.9507
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.001 0.0011 0.0136
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0051 0.1987
Onchocerca volvulus 0.0013 0.0022 0.0327
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0121 0.0402 0.1063
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0025 0.0064 0.11
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.008 0.0258 1
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.008 0.0258 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0013 0.0023 0.2205
Trypanosoma cruzi sterol 24-c-methyltransferase, putative 0.078 0.2713 0.7182
Brugia malayi AMP-binding enzyme family protein 0.0073 0.0233 0.0617
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0024 0.0058 0.2255
Brugia malayi heat shock protein 90 0.0031 0.0086 0.0228
Entamoeba histolytica cysteine protease, putative 0.0018 0.0039 0.1666
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.001 0.0011 0.0136
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0013 0.0023 0.2205
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.001 0.0011 0.003
Brugia malayi MH2 domain containing protein 0.0009 0.0006 0.0015
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0022 0.0051 0.0136
Mycobacterium leprae METHOXY MYCOLIC ACID SYNTHASE 1 MMAA1 (METHYL MYCOLIC ACID SYNTHASE 1) (MMA1) (HYDROXY MYCOLIC ACID SYNTHASE) 0.0039 0.0112 0.432
Mycobacterium ulcerans lipase LipD 0.0036 0.0103 0.3998
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.002 0.0046 0.1976
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0103 0.0273
Loa Loa (eye worm) hypothetical protein 0.0036 0.0103 0.0273
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.002 0.0046 0.0046
Mycobacterium leprae CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE 2 CMAA2 (CYCLOPROPANE FATTY ACID SYNTHASE) (CFA SYNTHASE) (CYCLOPROPANE MYCOLIC AC 0.0039 0.0112 0.432
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0055 0.0168 0.2126
Loa Loa (eye worm) MH2 domain-containing protein 0.0009 0.0006 0.0015
Echinococcus granulosus cpg binding protein 0.0014 0.0025 0.0025
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0102 0.027
Leishmania major heat shock protein 83-1 0.0031 0.0086 0.0228
Entamoeba histolytica heat shock protein 90, putative 0.0031 0.0086 0.3698
Echinococcus multilocularis tar DNA binding protein 0.0067 0.021 0.021
Leishmania major cathepsin L-like protease 0.0133 0.0442 0.117
Schistosoma mansoni smad1 5 8 and 0.0009 0.0006 0.0006
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0051 0.1987
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0046 0.0121
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.002 0.0046 0.0046
Schistosoma mansoni hypothetical protein 0.0007 0.0001 0.0001
Brugia malayi Cathepsin L-like precursor 0.0035 0.0098 0.026
Entamoeba histolytica cysteine proteinase, putative 0.0023 0.0058 0.2476
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.001 0.0011 0.0136
Schistosoma mansoni hypothetical protein 0.001 0.0011 0.0011
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0103 0.1307
Echinococcus multilocularis cysteine protease 0.0035 0.0098 0.0098
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0024 0.0058 0.0154
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0039 0.0103
Mycobacterium tuberculosis Conserved protein 0.0036 0.0103 0.1307
Onchocerca volvulus 0.0036 0.0103 0.1518
Entamoeba histolytica acyl-CoA synthetase, putative 0.0073 0.0233 1
Schistosoma mansoni smad1 5 8 and 0.0009 0.0006 0.0006
Toxoplasma gondii exonuclease III APE 0.0018 0.004 0.1535
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0133 0.0442 0.117
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0102 0.9873
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0078 0.0249 0.0249
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0051 0.1987
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0022 0.0051 0.1987
Loa Loa (eye worm) hypothetical protein 0.0554 0.1919 0.508
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0039 0.0039
Entamoeba histolytica cysteine protease, putative 0.0018 0.0039 0.1666
Trypanosoma cruzi heat shock protein 85, putative 0.0025 0.0064 0.0169
Onchocerca volvulus 0.0035 0.0098 0.1444
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0103 1
Schistosoma mansoni cpg binding protein 0.0014 0.0025 0.0025
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0103 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0098 0.9507
Leishmania major heat shock protein 83-1 0.0031 0.0086 0.0228
Entamoeba histolytica recQ family helicase, putative 0.001 0.001 0.0434
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.001 0.0011 0.0136
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.002 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0023 0.0058 0.0153
Trypanosoma brucei heat shock protein, putative 0.0031 0.0086 0.0228
Echinococcus granulosus Smad4 0.0009 0.0006 0.0006
Plasmodium vivax vivapain-2 0.0035 0.0098 0.3801
Schistosoma mansoni DNA helicase recq5 0.002 0.0046 0.0046
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0102 0.4375
Mycobacterium ulcerans cyclopropane-fatty-acyl-phospholipid synthase 2 CmaA2 0.0039 0.0112 0.432
Loa Loa (eye worm) hypothetical protein 0.0039 0.0112 0.0295
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0013 0.0021 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0046 0.446
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0013 0.0021 0.0902
Trypanosoma cruzi Emopamil binding protein, putative 0.0138 0.0462 0.1222
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0102 0.9873
Schistosoma mansoni smad 0.0009 0.0006 0.0006
Echinococcus granulosus ATP dependent DNA helicase Q1 0.002 0.0046 0.0046
Plasmodium falciparum heat shock protein 90, putative 0.0013 0.0021 0.0814
Schistosoma mansoni tar DNA-binding protein 0.0067 0.021 0.021
Trypanosoma cruzi major cysteine proteinase, putative 0.0104 0.0342 0.0906
Echinococcus granulosus tumor protein p63 0.1371 0.4787 0.4787
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0098 0.9507
Toxoplasma gondii hypothetical protein 0.0028 0.0073 0.283
Brugia malayi Hsp90 protein 0.0013 0.0021 0.0056
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0102 0.9873
Giardia lamblia Kinase, CMGC MAPK 0.0024 0.0058 0.6759
Trichomonas vaginalis CMGC family protein kinase 0.0024 0.0058 0.5641
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0018 0.0039 0.0103
Schistosoma mansoni hypothetical protein 0.0007 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0039 0.0112 0.0295
Loa Loa (eye worm) cytochrome P450 family protein 0.0018 0.004 0.0107
Brugia malayi beta-lactamase 0.0036 0.0103 0.0273
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0028 0.0073 0.283
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0013 0.0023 0.0335
Echinococcus multilocularis hedgehog 0.0194 0.0658 0.0658
Schistosoma mansoni cellular tumor antigen P53 0.0201 0.068 0.068
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.008 0.0258 1
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.008 0.0258 1
Entamoeba histolytica hypothetical protein 0.0035 0.01 0.4271
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0022 0.0051 0.0649
Plasmodium falciparum acyl-CoA synthetase 0.0055 0.0168 0.6505
Trichomonas vaginalis CMGC family protein kinase 0.0024 0.0058 0.5641
Trypanosoma brucei heat shock protein, putative 0.0031 0.0086 0.0228
Echinococcus granulosus cysteine protease 0.0018 0.0039 0.0039
Trypanosoma brucei sterol 24-c-methyltransferase, putative 0.078 0.2713 0.7182
Mycobacterium ulcerans mycolic acid synthase UmaA 0.0039 0.0112 0.432
Trypanosoma brucei heat shock protein 90, putative 0.0031 0.0086 0.0228
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.001 0.0011 0.0136
Onchocerca volvulus 0.0035 0.0098 0.1444
Brugia malayi Cytochrome P450 family protein 0.0018 0.004 0.0107
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.001 0.0011 0.0028
Trypanosoma cruzi cytochrome P450, putative 0.0018 0.004 0.0107
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0039 0.1666
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.004 0.0105
Brugia malayi RNA recognition motif domain containing protein 0.0067 0.021 0.0556
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.001 0.0011 0.0136
Loa Loa (eye worm) heat shock protein 75 0.0013 0.0021 0.0056
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0182 0.0182
Onchocerca volvulus 0.0039 0.0112 0.1641
Brugia malayi Cathepsin L-like precursor 0.0035 0.0098 0.026
Mycobacterium ulcerans acyl-CoA synthetase 0.0073 0.0233 0.9023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0098 0.9507
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.001 0.0011 0.0136
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.001 0.0011 0.0136
Brugia malayi Glycosyl hydrolases family 31 protein 0.0162 0.0544 0.1441
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0103 0.1307
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0138 0.0462 0.1222
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0023 0.2205
Mycobacterium leprae Probable lipase LipE 0.0036 0.0103 0.3998
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0051 0.1987
Schistosoma mansoni hypothetical protein 0.0007 0.0001 0.0001
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.001 0.0011 0.0415
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0022 0.0051 0.0136
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0138 0.0462 0.1222
Brugia malayi beta-lactamase family protein 0.0036 0.0103 0.0273
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0052 0.0157 0.1993
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.002 0.0046 0.0122
Loa Loa (eye worm) cytochrome P450 family protein 0.0018 0.004 0.0107
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.001 0.0011 0.0415
Loa Loa (eye worm) transcription factor SMAD2 0.0125 0.0415 0.1098
Echinococcus multilocularis heat shock protein 90 0.0025 0.0064 0.0064
Mycobacterium leprae MYCOLIC ACID SYNTHASE PCAA (CYCLOPROPANE SYNTHASE) 0.0039 0.0112 0.432
Schistosoma mansoni microtubule-associated protein tau 0.2857 1 1
Trypanosoma cruzi heat shock protein 85, putative 0.0031 0.0086 0.0228
Brugia malayi Glycosyl hydrolases family 31 protein 0.0013 0.0023 0.006
Loa Loa (eye worm) hypothetical protein 0.001 0.0011 0.003
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0182 0.7048
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.008 0.0258 1
Onchocerca volvulus Cathepsin F homolog 0.0035 0.0098 0.1444
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0028 0.0073 0.283
Brugia malayi latrophilin 2 splice variant baaae 0.0016 0.0031 0.0082
Leishmania major hypothetical protein, conserved 0.0138 0.0462 0.1222
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0098 0.9507
Echinococcus granulosus smad 0.0009 0.0006 0.0006
Leishmania major C-8 sterol isomerase-like protein 0.1084 0.3778 1
Brugia malayi Cathepsin L-like precursor 0.0035 0.0098 0.026
Brugia malayi MH1 domain containing protein 0.0009 0.0006 0.0015
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0022 0.0051 0.1987
Mycobacterium tuberculosis Methoxy mycolic acid synthase 3 MmaA3 (methyl mycolic acid synthase 3) (MMA3) (hydroxy mycolic acid synthase) 0.0039 0.0112 0.1412
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.007 0.0184
Trypanosoma brucei C-8 sterol isomerase, putative 0.1084 0.3778 1
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0039 0.1666
Loa Loa (eye worm) hypothetical protein 0.0022 0.0051 0.0136
Echinococcus multilocularis cpg binding protein 0.0014 0.0025 0.0025
Trypanosoma brucei heat shock protein 90, putative 0.0031 0.0086 0.0228
Onchocerca volvulus 0.0036 0.0103 0.1518
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0055 0.0168 0.6505
Leishmania major heat shock protein 83-1 0.0031 0.0086 0.0228
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.001 0.0011 0.0136
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0064 0.6168
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.001 0.001 0.0391
Schistosoma mansoni alpha-glucosidase 0.0139 0.0465 0.0465
Onchocerca volvulus 0.0073 0.0233 0.3427
Echinococcus multilocularis cathepsin L 0.0018 0.0039 0.0039
Trypanosoma cruzi heat shock protein 85, putative 0.0031 0.0086 0.0228
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.0098 0.0098
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0098 0.4213
Brugia malayi Hint module family protein 0.0053 0.0161 0.0426
Leishmania major cytochrome p450-like protein 0.001 0.0011 0.0028
Trypanosoma cruzi C-8 sterol isomerase, putative 0.1084 0.3778 1
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0022 0.0051 0.1987
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.008 0.0258 1
Schistosoma mansoni cathepsin s 0.0012 0.0016 0.0016
Entamoeba histolytica acyl-CoA synthetase, putative 0.0073 0.0233 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0098 0.9507
Echinococcus granulosus dnaJ subfamily B 0.0189 0.0638 0.0638
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0022 0.0051 0.0649
Brugia malayi ERG2 and Sigma1 receptor like protein 0.1084 0.3778 1
Echinococcus multilocularis bloom syndrome protein 0.002 0.0046 0.0046
Echinococcus multilocularis heat shock protein 0.0031 0.0086 0.0086
Plasmodium vivax unspecified product 0.0012 0.0016 0.0629
Loa Loa (eye worm) hypothetical protein 0.0012 0.0016 0.0043
Trypanosoma brucei heat shock protein, putative 0.0031 0.0086 0.0228
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.004 0.1535
Echinococcus granulosus Desert hedgehog protein 0.0194 0.0658 0.0658
Brugia malayi hypothetical protein 0.003 0.0082 0.0218
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.004 0.0502
Onchocerca volvulus 0.003 0.0082 0.1213
Loa Loa (eye worm) hypothetical protein 0.0053 0.0161 0.0426
Trypanosoma brucei sterol 24-c-methyltransferase, putative 0.078 0.2713 0.7182
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0102 0.027
Loa Loa (eye worm) hypothetical protein 0.0073 0.0233 0.0617
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0022 0.0051 0.0051
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.01 0.01
Trichomonas vaginalis heat shock protein, putative 0.0031 0.0086 0.8346
Brugia malayi AMP-binding enzyme family protein 0.0073 0.0233 0.0617
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0103 0.0103
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0051 0.0136
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0035 0.0098 0.0098
Entamoeba histolytica cysteine protease, putative 0.0018 0.0039 0.1666
Entamoeba histolytica cysteine protease, putative 0.0018 0.0039 0.1666
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0007 0.0001 0.0001
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.001 0.0011 0.0444
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0098 0.9507
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0025 0.0064 0.0169
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0098 0.9507
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.001 0.0011 0.0415
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0058 0.5588
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0013 0.0021 0.0309
Echinococcus multilocularis jun protein 0.0039 0.0112 0.0112
Schistosoma mansoni heat shock protein 0.0031 0.0086 0.0086
Plasmodium falciparum endoplasmin, putative 0.0019 0.0043 0.1684
Leishmania major acetyl-CoA synthetase, putative 0.0022 0.0051 0.0136
Brugia malayi Cathepsin L-like precursor 0.0012 0.0016 0.0043
Echinococcus multilocularis cysteine protease 0.0035 0.0098 0.0098
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0022 0.0051 0.0136
Toxoplasma gondii cathepsin CPL 0.0035 0.0098 0.3801
Echinococcus granulosus cytochrome P450 2K1 0.001 0.0011 0.0011
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.004 0.004
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0022 0.0051 0.2202
Trypanosoma brucei heat shock protein, putative 0.0031 0.0086 0.0228
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.001 0.0011 0.0136
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0013 0.0021 0.0021
Entamoeba histolytica recQ family DNA helicase 0.001 0.0011 0.0492
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0103 0.1307
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0039 0.0039
Toxoplasma gondii propionate-CoA ligase 0.0022 0.0051 0.1987
Schistosoma mansoni serine/threonine protein kinase 0.0024 0.0058 0.0058
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.002 0.0046 0.0046
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0022 0.0051 0.0649
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0009 0.0006 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0133 0.0442 0.117
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.001 0.0011 0.0415
Schistosoma mansoni cathepsin F (C01 family) 0.0023 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.001 0.0011 0.003
Echinococcus granulosus endoplasmin 0.0025 0.0064 0.0064
Echinococcus granulosus mothers against decapentaplegic 5 0.0009 0.0006 0.0006
Trichomonas vaginalis CMGC family protein kinase 0.0024 0.0058 0.5641
Leishmania major cathepsin L-like protease 0.0133 0.0442 0.117
Mycobacterium leprae METHOXY MYCOLIC ACID SYNTHASE 4 MMAA4 (METHYL MYCOLIC ACID SYNTHASE 4) (MMA4) (HYDROXY MYCOLIC ACID SYNTHASE) 0.0039 0.0112 0.432
Toxoplasma gondii heat shock protein HSP90 0.0031 0.0086 0.3337
Trypanosoma cruzi heat shock protein 90, putative 0.0025 0.0064 0.0169
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0064 0.6168
Echinococcus multilocularis heat shock protein 90 0.0031 0.0086 0.0086
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0046 0.1773
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0133 0.0442 0.117
Echinococcus multilocularis 0.001 0.0011 0.0011
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0024 0.0058 0.0154
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0103 0.1307
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0073 0.0233 0.9023
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.002 0.0046 0.0046
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0053 0.0161 0.2036
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.002 0.0046 0.446
Trypanosoma brucei Sterol methyltransferase, putative 0.078 0.2713 0.7182
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0022 0.0051 0.1987
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0022 0.0051 0.0649
Leishmania major 4-coumarate:coa ligase-like protein 0.0073 0.0233 0.0617
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0067 0.021 0.0556
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.001 0.0011 0.0415
Mycobacterium ulcerans cyclopropane-fatty-acyl-phospholipid synthase 0.0039 0.0112 0.432
Leishmania major glycosyl hydrolase-like protein 0.0013 0.0023 0.006
Loa Loa (eye worm) hypothetical protein 0.0035 0.0098 0.026
Onchocerca volvulus 0.0035 0.0098 0.1444
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0035 0.0098 0.3801
Trypanosoma cruzi cytochrome p450-like protein, putative 0.001 0.0011 0.0028
Loa Loa (eye worm) hypothetical protein 0.0073 0.0233 0.0617
Toxoplasma gondii heat shock protein 75, putative 0.0013 0.0021 0.0814
Toxoplasma gondii ABC1 family protein 0.0036 0.0103 0.3998
Brugia malayi Cytochrome P450 family protein 0.001 0.0011 0.0028
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0035 0.0098 0.3801
Echinococcus granulosus cathepsin L cysteine proteinase 0.0035 0.0098 0.0098
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0013 0.0023 0.006
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.008 0.0258 0.0258
Echinococcus multilocularis endoplasmin 0.0025 0.0064 0.0064
Trypanosoma cruzi Heat shock protein 83, putative 0.0031 0.0086 0.0228
Entamoeba histolytica cysteine protease, putative 0.0018 0.0039 0.1666
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0039 0.1666
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0023 0.0056 0.0149
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.001 0.0011 0.003
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0022 0.0051 0.1987
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.01 0.01
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0103 1
Trypanosoma brucei Emopamil binding protein, putative 0.0138 0.0462 0.1222
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0007 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0098 0.9507
Mycobacterium leprae POSSIBLE FATTY ACID SYNTHASE 0.0039 0.0112 0.432
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0025 0.0064 0.2466
Loa Loa (eye worm) hypothetical protein 0.0008 0.0006 0.0015
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0039 0.0039
Echinococcus granulosus GPCR family 2 0.0007 0.0001 0.0001
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0022 0.0051 0.1987
Trichomonas vaginalis antibiotic synthetase, putative 0.0022 0.0051 0.4968
Brugia malayi Cathepsin L-like precursor 0.0023 0.0058 0.0153
Mycobacterium ulcerans acetyl-CoA synthetase 0.0022 0.0051 0.1987
Echinococcus multilocularis cathepsin L cysteine protease 0.0035 0.0098 0.0098
Giardia lamblia Grp94/Hsp90 0.0025 0.0064 0.7391
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0051 0.0649
Loa Loa (eye worm) hypothetical protein 0.0036 0.0103 0.0273
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0046 0.4436
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0103 1
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0064 0.6168
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0039 0.0112 0.0112
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0046 0.0121
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0102 0.027
Brugia malayi MAP kinase sur-1 0.0024 0.0058 0.0154
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0051 0.1987
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.001 0.0011 0.0028
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0098 0.4213
Loa Loa (eye worm) latrophilin receptor protein 2 0.0007 0.0001 0.0003
Echinococcus multilocularis lysosomal alpha glucosidase 0.0162 0.0544 0.0544
Giardia lamblia Heat shock protein HSP 90-alpha 0.0031 0.0086 1
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.002 0.0046 0.0122
Leishmania major lanosterol 14-alpha-demethylase, putative 0.001 0.0011 0.0028

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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