Detailed information for compound 619507

Basic information

Technical information
  • TDR Targets ID: 619507
  • Name: 1-(4-methylphenyl)-1,2,3,4-tetrahydropyrrolo[ 1,2-a]pyrazine
  • MW: 212.29 | Formula: C14H16N2
  • H donors: 1 H acceptors: 0 LogP: 1.83 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc(cc1)C1NCCn2c1ccc2
  • InChi: 1S/C14H16N2/c1-11-4-6-12(7-5-11)14-13-3-2-9-16(13)10-8-15-14/h2-7,9,14-15H,8,10H2,1H3
  • InChiKey: JIDRGEGDAHDJFW-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0017 0.0002 0.0031
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0008 0.0008
Schistosoma mansoni cpg binding protein 0.0114 0.0225 0.0225
Echinococcus granulosus beta LACTamase domain containing family member 0.0144 0.0292 0.0292
Brugia malayi diacylglycerol acyltransferase 0.0378 0.0828 0.0828
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0006
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0006 0.0078
Loa Loa (eye worm) hypothetical protein 0.0378 0.0828 0.0826
Trichomonas vaginalis conserved hypothetical protein 0.0378 0.0828 0.3877
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0011
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0378 0.0828 1
Trypanosoma cruzi GUP1, putative 0.0378 0.0828 1
Entamoeba histolytica vacuolar protein sorting 26 0.0378 0.0828 1
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.0303 0.0657 0.3182
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0041 0.0057 0.0055
Mycobacterium ulcerans aldehyde dehydrogenase 0.0017 0.0002 0.0031
Trypanosoma brucei delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0017 0.0002 0.0025
Treponema pallidum exodeoxyribonuclease (exoA) 0.0038 0.0051 0.0622
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.004 0.0054 0.0819
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0067 0.0805
Schistosoma mansoni survival motor neuron protein 0.0096 0.0182 0.0182
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0378 0.0828 0.0828
Onchocerca volvulus 0.004 0.0056 0.0251
Trichomonas vaginalis succinate semialdehyde dehydrogenase, putative 0.0017 0.0002 0.001
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0051 0.0049
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0051 0.0051
Echinococcus granulosus ornithine aminotransferase 0.0043 0.0062 0.0062
Mycobacterium ulcerans lipase LipD 0.0144 0.0292 0.4399
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0105 0.0204 0.0987
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.02 0.0937
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0006 0.0078
Mycobacterium ulcerans hypothetical protein 0.0144 0.0292 0.4399
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0041 0.0057 0.0055
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0006 0.0054
Echinococcus multilocularis snurportin 1 0.0299 0.0649 0.0649
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0276 0.0595 0.0595
Brugia malayi CXXC zinc finger family protein 0.0114 0.0225 0.0225
Mycobacterium leprae PROBABLE GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE HEML (GSA) (GLUTAMATE-1-SEMIALDEHYDE AMINOTRANSFERASE) (GSA-AT) 0.0043 0.0062 0.0916
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0006 0.0031
Echinococcus granulosus tumor protein p63 0.0335 0.073 0.073
Brugia malayi ecdysteroid receptor 0.0041 0.0057 0.0057
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.004 0.0054 0.0264
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0023 0.0107
Plasmodium vivax multidomain scavenger receptor, putative 0.004 0.0056 0.0672
Onchocerca volvulus 0.0949 0.2137 1
Brugia malayi follicle stimulating hormone receptor 0.0454 0.1005 0.1005
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0378 0.0828 1
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0153 0.0314 0.0314
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0105 0.0204 0.0987
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0033 0.0039 0.0039
Leishmania major hypothetical protein, conserved 0.0144 0.0292 0.3528
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0006 0.0078
Mycobacterium tuberculosis Conserved protein 0.0144 0.0292 0.1416
Loa Loa (eye worm) hypothetical protein 0.0122 0.0242 0.024
Brugia malayi hypothetical protein 0.0181 0.0378 0.0378
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0019 0.0008 0.0008
Toxoplasma gondii cytochrome p450 superfamily protein 0.004 0.0054 0.0657
Echinococcus granulosus ecdysone induced protein 78C 0.0041 0.0057 0.0057
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0006 0.003
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0276 0.0595 0.0593
Mycobacterium tuberculosis Probable oxidoreductase 0.0117 0.0231 0.1117
Loa Loa (eye worm) glutathione reductase 0.0046 0.0069 0.0067
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.004 0.0054 0.0264
Schistosoma mansoni zinc finger protein 0.4381 1 1
Plasmodium falciparum thioredoxin reductase 0.0046 0.0069 0.0831
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0103 0.02 0.2416
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0023 0.0107
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0023 0.0107
Mycobacterium tuberculosis Probable hydrolase 0.0144 0.0292 0.1416
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.4381 1 1
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0151 0.0309 0.0309
Brugia malayi nuclear hormone receptor 0.0041 0.0057 0.0057
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0006 0.0078
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0008 0.0008
Leishmania major GTP-binding protein, putative 0.0021 0.0011 0.013
Plasmodium vivax SET domain protein, putative 0.0122 0.0242 0.2926
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.0051 0.8297
Schistosoma mansoni rab6-interacting 0.004 0.0056 0.0056
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0069 0.0334
Echinococcus granulosus neuropeptide receptor A26 0.0485 0.1074 0.1074
Mycobacterium tuberculosis Conserved protein 0.0144 0.0292 0.1416
Wolbachia endosymbiont of Brugia malayi bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 0.0017 0.0002 0.0332
Leishmania major pyrroline-5-carboxylate synthetase-like protein 0.0017 0.0002 0.0025
Brugia malayi Muscleblind-like protein 0.089 0.2003 0.2003
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0008 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0006 0.0078
Entamoeba histolytica hypothetical protein 0.0181 0.0378 0.4545
Loa Loa (eye worm) hypothetical protein 0.0028 0.0028 0.0026
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0006 0.0078
Schistosoma mansoni hypothetical protein 0.0299 0.0649 0.0649
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.004 0.0054 0.0264
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0023 0.0107
Leishmania major DNA polymerase eta, putative 0.0019 0.0006 0.0078
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0017 0.0002 0.0031
Plasmodium falciparum ornithine aminotransferase 0.0043 0.0062 0.0749
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0144 0.0292 0.1416
Schistosoma mansoni thyroid hormone receptor 0.0041 0.0057 0.0057
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.004 0.0054 0.0264
Brugia malayi MAP kinase sur-1 0.0103 0.02 0.02
Schistosoma mansoni aldehyde dehydrogenase 0.0306 0.0664 0.0664
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0103 0.02 0.2416
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.014 0.0285 0.3438
Trichomonas vaginalis conserved hypothetical protein 0.0151 0.0309 0.1445
Mycobacterium ulcerans aldehyde dehydrogenase 0.0306 0.0664 1
Mycobacterium tuberculosis Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase) 0.0043 0.0062 0.0301
Loa Loa (eye worm) hypothetical protein 0.089 0.2003 0.2001
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0056 0.0056
Brugia malayi steroid hormone receptor 0.0041 0.0057 0.0057
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0103 0.02 0.2416
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0151 0.0309 0.0309
Schistosoma mansoni aldehyde dehydrogenase 0.0017 0.0002 0.0002
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0151 0.0309 0.0309
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0117 0.0231 0.1117
Schistosoma mansoni hypothetical protein 0.0017 0.0002 0.0002
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0017 0.0002 0.0025
Loa Loa (eye worm) doublecortin family protein 0.004 0.0056 0.0054
Plasmodium falciparum glutathione reductase 0.0046 0.0069 0.0831
Onchocerca volvulus Huntingtin homolog 0.0126 0.0252 0.1171
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0041 0.0041
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.004 0.0054 0.0264
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0105 0.0204 0.3081
Brugia malayi nuclear receptor NHR-88 0.0019 0.0008 0.0008
Entamoeba histolytica hypothetical protein, conserved 0.0378 0.0828 1
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.004 0.0054 0.0819
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0051 0.0622
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0179 0.0373 0.0373
Echinococcus granulosus mitogen activated protein kinase 3 0.0103 0.02 0.02
Schistosoma mansoni cpg binding protein 0.0121 0.024 0.024
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Brugia malayi cytochrome P450 0.004 0.0054 0.0054
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0019 0.0008 0.0008
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0306 0.0664 0.0664
Loa Loa (eye worm) hypothetical protein 0.0151 0.0309 0.0307
Brugia malayi nuclear receptor RXR 0.0019 0.0008 0.0008
Mycobacterium tuberculosis Conserved protein 0.0144 0.0292 0.1416
Loa Loa (eye worm) hypothetical protein 0.0049 0.0077 0.0075
Loa Loa (eye worm) beta-lactamase 0.0144 0.0292 0.029
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0151 0.0309 0.3726
Schistosoma mansoni hypothetical protein 0.0022 0.0015 0.0015
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0069 0.0831
Onchocerca volvulus Huntingtin homolog 0.0126 0.0252 0.1171
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0016 0.0188
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0153 0.0314 0.0314
Leishmania major cytochrome p450-like protein 0.0058 0.0096 0.116
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0077 0.0077
Giardia lamblia DINP protein human, muc B family 0.0019 0.0006 0.021
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0011 0.013
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0023 0.0107
Echinococcus multilocularis microtubule associated protein 2 0.1379 0.3123 0.3123
Toxoplasma gondii gamma-glutamyl phosphate reductase, putative 0.0017 0.0002 0.0025
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0041 0.0057 0.0057
Schistosoma mansoni loxhd1 0.004 0.0056 0.0056
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1617 0.3667 0.3667
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0144 0.0292 0.029
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0276 0.0595 0.0595
Mycobacterium ulcerans gamma-aminobutyraldehyde dehydrogenase 0.0017 0.0002 0.0031
Toxoplasma gondii histone lysine methyltransferase SET1 0.0225 0.0478 0.5775
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0378 0.0828 0.0828
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0059 0.0712
Echinococcus multilocularis betaine aldehyde dehydrogenase 0.0017 0.0002 0.0002
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0006 0.0006
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0013 0.0013
Onchocerca volvulus 0.0096 0.0182 0.0844
Leishmania major aldehyde dehydrogenase, putative 0.0017 0.0002 0.0025
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0306 0.0664 0.3219
Toxoplasma gondii hypothetical protein 0.0048 0.0073 0.0881
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0011 0.013
Echinococcus multilocularis mitogen activated protein kinase 0.0103 0.02 0.02
Mycobacterium ulcerans glutamate-1-semialdehyde aminotransferase 0.0043 0.0062 0.0934
Echinococcus multilocularis zinc finger protein 0.4004 0.9135 0.9135
Loa Loa (eye worm) hypothetical protein 0.0041 0.0057 0.0055
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0378 0.0828 0.0828
Trypanosoma brucei PAB1-binding protein , putative 0.005 0.0077 0.0933
Entamoeba histolytica Ran family GTPase 0.0021 0.0011 0.0105
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0022 0.0013 0.0011
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0016 0.0073
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0022 0.0013 0.0013
Schistosoma mansoni ap endonuclease 0.0038 0.0051 0.0051
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0076 0.0076
Schistosoma mansoni RAR-like nuclear receptor 0.0041 0.0057 0.0057
Entamoeba histolytica hypothetical protein 0.0181 0.0378 0.4545
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0011 0.0011
Echinococcus multilocularis survival motor neuron protein 1 0.0468 0.1036 0.1036
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0006 0.0078
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.0057 0.0057
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0051 0.0249
Schistosoma mansoni zinc finger protein 0.0019 0.0008 0.0008
Brugia malayi Steroid receptor seven-up type 2 0.0041 0.0057 0.0057
Loa Loa (eye worm) nuclear hormone receptor 0.0019 0.0008 0.0006
Brugia malayi 4-aminobutyrate aminotransferase, mitochondrial precursor 0.0043 0.0062 0.0062
Leishmania major hypothetical protein, conserved 0.0378 0.0828 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0041 0.0057 0.0055
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0006 0.003
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0122 0.0242 0.0242
Mycobacterium ulcerans bifunctional acetaldehyde-CoA/alcohol dehydrogenase 0.0017 0.0002 0.0031
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0011
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0043 0.0062 0.0934
Brugia malayi hypothetical protein 0.0126 0.0252 0.0252
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0117 0.0231 0.349
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.004 0.0054 0.0264
Leishmania major glycerol uptake protein, putative 0.0378 0.0828 1
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0069 0.0831
Mycobacterium tuberculosis Possible succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD2 0.0017 0.0002 0.001
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.004 0.0054 0.0264
Brugia malayi nuclear receptor NHR-88 0.0041 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.004 0.0056 0.0054
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0041 0.0057 0.0057
Trypanosoma cruzi cytochrome P450, putative 0.0058 0.0096 0.116
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0051 0.0598
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0378 0.0828 0.0828
Mycobacterium leprae Probable Acetylornithine aminotransferase ArgD 0.0043 0.0062 0.0916
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0011 0.013
Mycobacterium tuberculosis Probable aldehyde dehydrogenase (NAD+) dependent 0.0017 0.0002 0.001
Echinococcus granulosus FTZ F1 alpha 0.0041 0.0057 0.0057
Schistosoma mansoni importin beta-1 0.0028 0.0028 0.0028
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0067 0.0312
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.02 0.0937
Plasmodium vivax importin-beta 2, putative 0.0028 0.0028 0.0335
Onchocerca volvulus 0.0041 0.0057 0.0258
Brugia malayi Thioredoxin reductase 0.0046 0.0069 0.0069
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0017 0.0002 0.0025
Plasmodium falciparum importin beta, putative 0.0028 0.0028 0.0335
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0122 0.0242 0.0242
Plasmodium falciparum LCCL domain-containing protein 0.004 0.0056 0.0672
Loa Loa (eye worm) histone methyltransferase 0.004 0.0055 0.0053
Leishmania major DNA polymerase kappa, putative 0.0019 0.0006 0.0078
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0028 0.0335
Echinococcus granulosus Aminotransferase class III 0.0043 0.0062 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0023 0.0107
Loa Loa (eye worm) cytochrome P450 family protein 0.0058 0.0096 0.0094
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0051 0.0051
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0006 0.0078
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0067 0.0805
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0006 0.0006
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0151 0.0309 0.0309
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0019 0.0008 0.0008
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.014 0.0285 0.3438
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0006 0.0098
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0019 0.0008 0.0008
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0056 0.0056
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.004 0.0054 0.0819
Onchocerca volvulus 0.0049 0.0076 0.0345
Echinococcus granulosus succinate semialdehyde dehydrogenase 0.0017 0.0002 0.0002
Loa Loa (eye worm) CXXC zinc finger family protein 0.0114 0.0225 0.0223
Brugia malayi Importin beta-1 subunit 0.0028 0.0028 0.0028
Trichomonas vaginalis penicillin-binding protein, putative 0.0144 0.0292 0.1368
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0023 0.0107
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0144 0.0292 0.0292
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0017 0.0002 0.0025
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0011 0.0011
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0051 0.0051
Brugia malayi acetyltransferase, GNAT family protein 0.0153 0.0314 0.0314
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0023 0.0107
Loa Loa (eye worm) CYP4Cod1 0.0058 0.0096 0.0094
Echinococcus multilocularis muscleblind protein 0.089 0.2003 0.2003
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0051 0.0622
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0023 0.0107
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0041 0.0057 0.0055
Trypanosoma cruzi glycerol uptake protein, putative 0.0378 0.0828 1
Schistosoma mansoni aldehyde dehydrogenase 0.0017 0.0002 0.0002
Schistosoma mansoni nuclear receptor 0.0019 0.0008 0.0008
Toxoplasma gondii aldehyde dehydrogenase (NAD) family protein 0.0017 0.0002 0.0025
Brugia malayi Hhat protein 0.0378 0.0828 0.0828
Echinococcus granulosus neuropeptide s receptor 0.0485 0.1074 0.1074
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0378 0.0828 0.0828
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0033 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.009 0.0169 0.0167
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0006
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0041 0.0057 0.0057
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0017 0.0002 0.0002
Mycobacterium tuberculosis Probable methylmalonate-semialdehyde dehydrogenase MmsA (methylmalonic acid semialdehyde dehydrogenase) (MMSDH) 0.0017 0.0002 0.001
Schistosoma mansoni aldehyde dehydrogenase 0.0017 0.0002 0.0002
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0041 0.0057 0.0057
Loa Loa (eye worm) MBOAT family protein 0.4381 1 1
Brugia malayi F/Y-rich N-terminus family protein 0.0039 0.0054 0.0054
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0013 0.0013
Brugia malayi hypothetical protein 0.0022 0.0013 0.0013
Brugia malayi beta-lactamase 0.0144 0.0292 0.0292
Entamoeba histolytica hypothetical protein 0.0181 0.0378 0.4545
Trichomonas vaginalis D-aminoacylase, putative 0.0144 0.0292 0.1368
Echinococcus multilocularis mitogen activated protein kinase 3 0.0103 0.02 0.02
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0022 0.0015 0.0015
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0067 0.0805
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.0057 0.0057
Brugia malayi Succinate semialdehyde dehydrogenase, mitochondrial precursor 0.0017 0.0002 0.0002
Echinococcus multilocularis nuclear receptor nhr 48 0.0019 0.0008 0.0008
Treponema pallidum gamma-glutamyl phosphate reductase 0.0017 0.0002 0.0025
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0067 0.0312
Mycobacterium tuberculosis Probable aldehyde dehydrogenase NAD dependent AldA (aldehyde dehydrogenase [NAD+]) 0.0017 0.0002 0.001
Echinococcus granulosus ubiquitin specific protease 41 0.0151 0.0309 0.0309
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0006
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0023 0.0107
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0023 0.0107
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0096 0.0182 0.0182
Brugia malayi Nuclear hormone receptor-like 1 0.0041 0.0057 0.0057
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.004 0.0054 0.0264
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0006
Brugia malayi Doublecortin family protein 0.004 0.0056 0.0056
Mycobacterium ulcerans aldehyde dehydrogenase 0.0306 0.0664 1
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0019 0.0008 0.0008
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.0303 0.0657 0.3074
Onchocerca volvulus 0.0019 0.0008 0.0026
Schistosoma mansoni lipoxygenase 0.0179 0.0373 0.0373
Echinococcus granulosus aldehyde dehydrogenase family 3 member B1 0.0017 0.0002 0.0002
Plasmodium vivax hypothetical protein, conserved 0.0144 0.0292 0.3528
Mycobacterium leprae Conserved hypothetical protein 0.004 0.0054 0.08
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 0.0017 0.0002 0.001
Schistosoma mansoni sterol O-acyltransferase 1 0.0378 0.0828 0.0828
Mycobacterium tuberculosis Probable reductase 0.0105 0.0204 0.0987
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.004 0.0056 0.0054
Leishmania major cytochrome p450-like protein 0.004 0.0054 0.0657
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.004 0.0054 0.0264
Leishmania major glycerol uptake protein, putative 0.0378 0.0828 1
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0296 0.0642 0.7754
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0144 0.0292 0.1416
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.004 0.0054 0.0819
Brugia malayi nuclear receptor NHR-67 0.0019 0.0008 0.0008
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0019 0.0008 0.0008
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0276 0.0595 0.0595
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.004 0.0054 0.0819
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0077 0.0933
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0006 0.0006
Schistosoma mansoni coup transcription factor 0.0041 0.0057 0.0057
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0144 0.0292 0.029
Schistosoma mansoni lipoxygenase 0.0107 0.0207 0.0207
Brugia malayi hypothetical protein 0.0019 0.0008 0.0008
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.004 0.0054 0.0819
Echinococcus multilocularis ornithine aminotransferase 0.0043 0.0062 0.0062
Echinococcus multilocularis FTZ F1 alpha 0.0041 0.0057 0.0057
Echinococcus multilocularis 0.004 0.0054 0.0054
Echinococcus granulosus histone acetyltransferase KAT2B 0.0149 0.0304 0.0304
Loa Loa (eye worm) acetyltransferase 0.0153 0.0314 0.0312
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.004 0.0054 0.0264
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0151 0.0309 0.0309
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0179 0.0373 0.0373
Plasmodium vivax ataxin-2 like protein, putative 0.005 0.0077 0.0933
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0006 0.0078
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0017 0.0002 0.0031
Echinococcus granulosus mixed lineage leukemia protein mll 0.0033 0.0039 0.0039
Schistosoma mansoni hypothetical protein 0.0378 0.0828 0.0828
Loa Loa (eye worm) hypothetical protein 0.0041 0.0057 0.0055
Mycobacterium ulcerans acetylornithine aminotransferase 0.0043 0.0062 0.0934
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0051 0.0622
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0028 0.0028
Mycobacterium ulcerans L-lysine aminotransferase 0.0043 0.0062 0.0934
Toxoplasma gondii thioredoxin reductase 0.0046 0.0069 0.0831
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0276 0.0595 0.0595
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.004 0.0054 0.0819
Echinococcus multilocularis ornithine aminotransferase 0.0043 0.0062 0.0062
Loa Loa (eye worm) steroid hormone receptor 0.0041 0.0057 0.0055
Brugia malayi ecdysone receptor 0.0019 0.0008 0.0008
Onchocerca volvulus 0.0144 0.0292 0.1359
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0017 0.0002 0.0025
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, GabD1 0.0017 0.0002 0.0031
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0069 0.0069
Brugia malayi hypothetical protein 0.005 0.0077 0.0077
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0834 0.1874 0.1872
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0028 0.0335
Echinococcus multilocularis sterol O acyltransferase 1 0.0378 0.0828 0.0828
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0006 0.0098
Brugia malayi nuclear receptor RXR 0.0022 0.0013 0.0013
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0306 0.0664 0.0664
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0041 0.0057 0.0057
Echinococcus granulosus dnaJ subfamily B 0.1229 0.2778 0.2778
Brugia malayi MBOAT family protein 0.0378 0.0828 0.0828
Brugia malayi Pre-SET motif family protein 0.0122 0.0242 0.0242
Echinococcus granulosus snurportin 1 0.0299 0.0649 0.0649
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0105 0.0204 0.0987
Plasmodium vivax glutathione reductase, putative 0.0046 0.0069 0.0831
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0051 0.0622
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0041 0.0057 0.0057
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0011 0.0011
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0017 0.0002 0.0025
Mycobacterium ulcerans hypothetical protein 0.0156 0.0321 0.4833
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0077 0.0075
Entamoeba histolytica hypothetical protein 0.0023 0.0016 0.0164
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0069 0.0067
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0041 0.0057 0.0057
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.004 0.0054 0.0657
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0006
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0022 0.0015 0.0015
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0454 0.1005 0.1003
Schistosoma mansoni nuclear hormone receptor 0.0041 0.0057 0.0057
Mycobacterium ulcerans gamma-glutamyl phosphate reductase 0.0017 0.0002 0.0031
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0056 0.0056
Schistosoma mansoni cytochrome P450 0.004 0.0054 0.0054
Trichomonas vaginalis helicase, putative 0.0026 0.0023 0.0107
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0122 0.0242 0.0242
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0041 0.0057 0.0057
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0043 0.0062 0.0934
Plasmodium falciparum histone acetyltransferase GCN5 0.0041 0.0058 0.0701
Trichomonas vaginalis penicillin-binding protein, putative 0.0144 0.0292 0.1368
Schistosoma mansoni aldehyde dehydrogenase 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0006
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0008 0.0026
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0105 0.0204 0.0987
Trypanosoma cruzi cytochrome P450, putative 0.0058 0.0096 0.116
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0006 0.0078
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0117 0.0231 0.1117
Brugia malayi orphan nuclear receptor NR2E1 0.0019 0.0008 0.0008
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.004 0.0054 0.0819
Echinococcus multilocularis cpg binding protein 0.0121 0.024 0.024
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0103 0.02 0.2416
Trypanosoma cruzi GUP1, putative 0.0378 0.0828 1
Echinococcus granulosus betaine aldehyde dehydrogenase 0.0017 0.0002 0.0002
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0019 0.0008 0.0026
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.0057 0.0057
Echinococcus granulosus mitogen activated protein kinase 0.0103 0.02 0.02
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0017 0.0002 0.0025
Toxoplasma gondii exonuclease III APE 0.0038 0.0051 0.0622
Brugia malayi conserved hypotetical protein 0.0019 0.0008 0.0008
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0017 0.0002 0.0025
Mycobacterium ulcerans aldehyde dehydrogenase 0.0306 0.0664 1
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0011 0.0009
Brugia malayi nuclear hormone receptor family member odr-7 0.0019 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0144 0.0292 0.029
Loa Loa (eye worm) hhat protein 0.0378 0.0828 0.0826
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0006
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.004 0.0054 0.0819
Brugia malayi MBOAT family protein 0.0378 0.0828 0.0828
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0023 0.0107
Trichomonas vaginalis conserved hypothetical protein 0.0378 0.0828 0.3877
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0006 0.0006
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0006 0.0006
Mycobacterium tuberculosis Probable lipase LipD 0.0144 0.0292 0.1416
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0103 0.02 0.2416
Echinococcus granulosus sterol O acyltransferase 1 0.0378 0.0828 0.0828
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0006 0.0031
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0041 0.0057 0.0057
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0017 0.0002 0.0031
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0103 0.02 0.2416
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0033 0.0039 0.0039
Mycobacterium ulcerans hypothetical protein 0.0303 0.0657 0.9887
Brugia malayi aldehyde dehydrogenase 0.0017 0.0002 0.0002
Mycobacterium tuberculosis Probable acetylornithine aminotransferase ArgD 0.0043 0.0062 0.0301
Onchocerca volvulus 0.0144 0.0292 0.1359
Loa Loa (eye worm) hhat protein 0.0378 0.0828 0.0826
Toxoplasma gondii ornithine aminotransferase, mitochondrial precursor, putative 0.0043 0.0062 0.0749
Onchocerca volvulus 0.0122 0.0242 0.1126
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.014 0.0285 0.3438
Loa Loa (eye worm) MBOAT family protein 0.0378 0.0828 0.0826
Echinococcus multilocularis Polycystic kidney disease protein 0.004 0.0056 0.0056
Echinococcus multilocularis dna polymerase eta 0.0019 0.0006 0.0006
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0122 0.0242 0.0242
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.004 0.0054 0.0819
Echinococcus granulosus survival motor neuron protein 1 0.0468 0.1036 0.1036
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0151 0.0309 0.3726
Trypanosoma brucei cytochrome P450, putative 0.0058 0.0096 0.116
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0151 0.0309 0.3711
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.004 0.0054 0.0264
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.004 0.0055 0.0055
Giardia lamblia Kinase, CMGC MAPK 0.0103 0.02 0.6485
Loa Loa (eye worm) hypothetical protein 0.0144 0.0292 0.029
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0041 0.0057 0.0055
Toxoplasma gondii aldehyde dehydrogenase 0.0306 0.0664 0.802
Trichomonas vaginalis conserved hypothetical protein 0.0378 0.0828 0.3877
Brugia malayi nuclear hormone receptor family member nhr-6 0.0019 0.0008 0.0008
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0378 0.0828 0.0828
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.004 0.0054 0.0819
Echinococcus granulosus cytochrome P450 2K1 0.004 0.0054 0.0054
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0008 0.0008
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0028 0.0335
Toxoplasma gondii hypothetical protein 0.0378 0.0828 1
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0017 0.0002 0.0025
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0069 0.0069
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.004 0.0054 0.0819
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0151 0.0309 0.3726
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0006
Mycobacterium ulcerans ornithine aminotransferase RocD1 and RocD2 0.0043 0.0062 0.0934
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0017 0.0002 0.0002
Trypanosoma cruzi cytochrome p450-like protein, putative 0.004 0.0054 0.0657
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0023 0.0107
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.02 0.02
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0041 0.0057 0.0057
Loa Loa (eye worm) cytochrome P450 0.004 0.0054 0.0052
Mycobacterium tuberculosis Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialde 0.0017 0.0002 0.001
Echinococcus multilocularis ubiquitin specific protease 41 0.0151 0.0309 0.0309
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0296 0.0642 0.7754
Trypanosoma brucei unspecified product 0.0019 0.0006 0.0078
Schistosoma mansoni hypothetical protein 0.0181 0.0378 0.0378
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0103 0.02 0.2416
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0033 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0041 0.0057 0.0055
Leishmania major delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0017 0.0002 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.0057 0.0057
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0056 0.0056
Mycobacterium ulcerans piperideine-6-carboxilic acid dehydrogenase Pcd 0.0017 0.0002 0.0031
Brugia malayi hypothetical protein 0.0022 0.0013 0.0013
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0041 0.0057 0.0057
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0022 0.0013 0.0013
Echinococcus multilocularis Fatty aldehyde dehydrogenase 0.0017 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0023 0.0107
Echinococcus granulosus o acyltransferase membrane bound domain 0.0378 0.0828 0.0828
Loa Loa (eye worm) hypothetical protein 0.0378 0.0828 0.0826
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0023 0.0107
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0017 0.0002 0.0025
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.004 0.0054 0.0819
Brugia malayi Aldehyde dehydrogenase protein 4 0.0017 0.0002 0.0002
Echinococcus granulosus nuclear receptor nhr 48 0.0019 0.0008 0.0008
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0151 0.0309 0.0309
Loa Loa (eye worm) hypothetical protein 0.0144 0.0292 0.029
Brugia malayi Cytochrome P450 family protein 0.0058 0.0096 0.0096
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0041 0.0057 0.0055
Brugia malayi MBOAT family protein 0.0378 0.0828 0.0828
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0378 0.0828 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0041 0.0057 0.0057
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.004 0.0054 0.0657
Schistosoma mansoni hypothetical protein 0.004 0.0054 0.0054
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0016 0.0073
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0181 0.0378 0.0378
Mycobacterium leprae Probable lipase LipE 0.0144 0.0292 0.4432
Loa Loa (eye worm) hypothetical protein 0.0041 0.0057 0.0055
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.004 0.0054 0.0657
Leishmania major importin beta-1 subunit, putative 0.0023 0.0016 0.0188
Echinococcus multilocularis aldehyde dehydrogenase family 3 member B1 0.0017 0.0002 0.0002
Treponema pallidum alginate O-acetylation protein (algI) 0.0378 0.0828 1
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0041 0.0057 0.0057
Brugia malayi Nuclear hormone receptor E75 0.0019 0.0008 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0006 0.0078
Loa Loa (eye worm) hypothetical protein 0.0041 0.0057 0.0055
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0276 0.0595 0.0595
Schistosoma mansoni hypothetical protein 0.004 0.0056 0.0056
Brugia malayi nuclear hormone receptor 0.0019 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.009 0.0169 0.0167
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0017 0.0002 0.0025
Loa Loa (eye worm) hypothetical protein 0.0126 0.0252 0.025
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0006 0.0078
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0378 0.0828 0.0828
Brugia malayi beta-lactamase family protein 0.0144 0.0292 0.0292
Trichomonas vaginalis ran, putative 0.0021 0.0011 0.005
Leishmania major hypothetical protein, conserved 0.005 0.0077 0.0933
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0144 0.0292 0.1416
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0378 0.0828 0.0828
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0011 0.013
Entamoeba histolytica hypothetical protein 0.0378 0.0828 1
Schistosoma mansoni hypothetical protein 0.1229 0.2778 0.2778
Giardia lamblia Alcohol dehydrogenase 0.0017 0.0002 0.0067
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.004 0.0054 0.0264
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0378 0.0828 1
Trypanosoma brucei aldehyde dehydrogenase family, putative 0.0017 0.0002 0.0025
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.004 0.0054 0.0264
Mycobacterium tuberculosis Probable esterase LipL 0.0144 0.0292 0.1416
Brugia malayi MBOAT family protein 0.0378 0.0828 0.0828
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0378 0.0828 0.0826
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0151 0.0309 0.1445
Trypanosoma brucei glycerol uptake protein, putative 0.0378 0.0828 1
Leishmania major glycerol uptake protein, putative 0.0378 0.0828 1
Onchocerca volvulus 0.0114 0.0225 0.1046
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0041 0.0057 0.0057
Leishmania major glycerol uptake protein, putative 0.0378 0.0828 1
Schistosoma mansoni microtubule-associated protein tau 0.1379 0.3123 0.3123
Schistosoma mansoni retinoic acid receptor RXR 0.0041 0.0057 0.0057
Onchocerca volvulus 0.004 0.0056 0.0251
Giardia lamblia Histone acetyltransferase GCN5 0.0041 0.0058 0.1881
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0378 0.0828 0.0828
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0103 0.02 0.0198
Trypanosoma cruzi hypothetical protein, conserved 0.0144 0.0292 0.3528
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0917 0.2064 1
Schistosoma mansoni delta 1-pyrroline-5-carboxylate synthetase 0.0017 0.0002 0.0002
Echinococcus granulosus RUN 0.004 0.0056 0.0056
Schistosoma mansoni ornithine--oxo-acid transaminase 0.0043 0.0062 0.0062
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0296 0.0642 0.7754
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0378 0.0828 0.0826
Trypanosoma cruzi delta-1-pyrroline-5-carboxylate dehydrogenase, putative 0.0017 0.0002 0.0025
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.004 0.0054 0.0264
Mycobacterium tuberculosis Conserved hypothetical protein 0.0156 0.0321 0.1555
Echinococcus granulosus microtubule associated protein 2 0.1379 0.3123 0.3123
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.004 0.0054 0.0264
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.004 0.0054 0.0264
Mycobacterium leprae Probable 4-aminobutyrate aminotransferase GabT (GAMMA-AMINO-N-BUTYRATE TRANSAMINASE) (GABA TRANSAMINASE) (GLUTAMATE:SUCCINIC SEM 0.0043 0.0062 0.0916
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.004 0.0054 0.0819
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0122 0.0242 0.0242
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0051 0.1668
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0378 0.0828 1
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.02 0.0937
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0058 0.0096 0.1446
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0276 0.0595 0.0595
Leishmania major glycerol uptake protein, putative 0.0378 0.0828 1
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0013 0.0013
Echinococcus granulosus Polycystic kidney disease protein 0.004 0.0056 0.0056
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0151 0.0309 1
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0023 0.0107
Leishmania major lanosterol 14-alpha-demethylase, putative 0.004 0.0054 0.0657
Loa Loa (eye worm) nuclear receptor NHR-67 0.0019 0.0008 0.0006
Trichomonas vaginalis transmembrane protein nessy, putative 0.0378 0.0828 0.3877
Toxoplasma gondii NADP-dependent succinate-semialdehyde dehydrogenase 0.0017 0.0002 0.0025
Entamoeba histolytica hypothetical protein 0.0181 0.0378 0.4545
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0122 0.0242 0.2926
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0016 0.0073
Echinococcus granulosus muscleblind protein 0.089 0.2003 0.2003
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.004 0.0054 0.0264
Mycobacterium ulcerans esterase/lipase LipP 0.0144 0.0292 0.4399
Brugia malayi tailless protein 0.0019 0.0008 0.0008
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.004 0.0054 0.0819
Loa Loa (eye worm) hypothetical protein 0.0378 0.0828 0.0826
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0041 0.0057 0.0057
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0041 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0049 0.0076 0.0074
Brugia malayi hypothetical protein 0.0032 0.0037 0.0037
Trypanosoma cruzi glycerol uptake protein, putative 0.0378 0.0828 1
Schistosoma mansoni ap endonuclease 0.0038 0.0051 0.0051
Schistosoma mansoni hypothetical protein 0.0034 0.0041 0.0041
Mycobacterium tuberculosis Probable lipase LipE 0.0144 0.0292 0.1416
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0378 0.0828 0.0828
Trypanosoma brucei trypanothione reductase 0.0046 0.0069 0.0831
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0006 0.0078
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0151 0.0309 0.1445
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0011 0.013
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0051 0.0241
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.004 0.0054 0.0819
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0378 0.0828 1
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0017 0.0002 0.0025
Echinococcus granulosus o acyltransferase membrane bound domain 0.0378 0.0828 0.0828
Loa Loa (eye worm) hypothetical protein 0.089 0.2003 0.2001
Echinococcus multilocularis beta LACTamase domain containing family member 0.0144 0.0292 0.0292
Trypanosoma brucei hypothetical protein, conserved 0.0144 0.0292 0.3528
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0144 0.0292 0.0292
Mycobacterium tuberculosis Probable aldehyde dehydrogenase AldC 0.0017 0.0002 0.001
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0041 0.0057 0.0057
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0006 0.0078
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0247 0.0529 0.0529
Brugia malayi Cytochrome P450 family protein 0.0058 0.0096 0.0096
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0006 0.0078
Onchocerca volvulus Bile acid receptor homolog 0.0041 0.0057 0.0258
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0008 0.0008
Loa Loa (eye worm) cytochrome P450 family protein 0.0156 0.0321 0.0319
Brugia malayi Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor 0.0017 0.0002 0.0002
Trichomonas vaginalis D-aminoacylase, putative 0.0144 0.0292 0.1368
Mycobacterium ulcerans pyrroline-5-carboxylate dehydrogenase, RocA 0.0017 0.0002 0.0031
Leishmania major mitochondrial DNA polymerase beta 0.0296 0.0642 0.7754
Echinococcus multilocularis thyroid hormone receptor alpha 0.0041 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0126 0.0252 0.025
Echinococcus granulosus dna polymerase kappa 0.0019 0.0006 0.0006
Brugia malayi hypothetical protein 0.0468 0.1036 0.1036
Onchocerca volvulus Protein ultraspiracle homolog 0.0041 0.0057 0.0258
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0006
Echinococcus multilocularis neuropeptide receptor A26 0.0485 0.1074 0.1074
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0299 0.0649 0.0647
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.004 0.0054 0.0819
Loa Loa (eye worm) hypothetical protein 0.0144 0.0292 0.029
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0041 0.0057 0.0057
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.0057 0.0057
Leishmania major aldehyde dehydrogenase, putative 0.0017 0.0002 0.0025
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0011 0.0349
Schistosoma mansoni hypothetical protein 0.0096 0.0182 0.0182
Trypanosoma brucei glycerol uptake protein, putative 0.0378 0.0828 1
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase [NADP+] dependent, PutA_2 0.0017 0.0002 0.0031
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0006 0.0078
Trypanosoma cruzi aldehyde dehydrogenase family, putative 0.0017 0.0002 0.0025
Loa Loa (eye worm) hypothetical protein 0.0468 0.1036 0.1034
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0019 0.0008 0.0006
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0378 0.0828 0.0828
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0041 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0378 0.0828 0.0826
Wolbachia endosymbiont of Brugia malayi acetylornithine transaminase protein 0.0043 0.0062 1
Brugia malayi hypothetical protein 0.004 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0011
Brugia malayi Cytochrome P450 family protein 0.004 0.0054 0.0054
Echinococcus granulosus histone lysine methyltransferase setb 0.0122 0.0242 0.0242
Mycobacterium tuberculosis Probable ornithine aminotransferase (N-terminus part) RocD1 (ornithine--oxo-acid aminotransferase) 0.0043 0.0062 0.0301
Brugia malayi glutathione reductase 0.0046 0.0069 0.0069
Schistosoma mansoni rab6-interacting 0.004 0.0056 0.0056
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.0303 0.0657 1
Schistosoma mansoni ran 0.0021 0.0011 0.0011
Mycobacterium ulcerans beta-lactamase 0.0144 0.0292 0.4399
Mycobacterium leprae conserved hypothetical protein 0.0144 0.0292 0.4432
Trichomonas vaginalis porcupine, putative 0.0378 0.0828 0.3877
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0006 0.0006
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0022 0.0013 0.0013
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0006 0.0078
Echinococcus multilocularis muscleblind protein 1 0.089 0.2003 0.2003
Toxoplasma gondii LsmAD domain-containing protein 0.005 0.0077 0.0933
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0041 0.0057 0.0057
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0019 0.0008 0.0008
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0378 0.0828 0.0828
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0103 0.02 0.2416
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0306 0.0664 0.802
Trichomonas vaginalis esterase, putative 0.0144 0.0292 0.1368
Loa Loa (eye worm) DR-78 0.0019 0.0008 0.0006
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0006 0.0078
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0077 0.0933
Echinococcus granulosus zinc finger protein 0.4004 0.9135 0.9135
Echinococcus multilocularis RUN 0.004 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0034 0.0041 0.0039
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0041 0.0057 0.0055
Schistosoma mansoni cpg binding protein 0.0121 0.024 0.024
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0276 0.0595 0.0595
Brugia malayi Pre-SET motif family protein 0.0834 0.1874 0.1874
Onchocerca volvulus 0.0144 0.0292 0.1359
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0006 0.0078
Schistosoma mansoni thyroid hormone receptor 0.0041 0.0057 0.0057
Mycobacterium tuberculosis Probable aminotransferase 0.0303 0.0657 0.3182
Trypanosoma cruzi hypothetical protein, conserved 0.0144 0.0292 0.3528
Mycobacterium tuberculosis Probable pyrroline-5-carboxylate dehydrogenase RocA 0.0017 0.0002 0.001
Trichomonas vaginalis set domain proteins, putative 0.0949 0.2137 1
Mycobacterium tuberculosis Probable dehydrogenase 0.0105 0.0204 0.0987
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0378 0.0828 0.0828
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0051 0.0241
Loa Loa (eye worm) cytochrome P450 family protein 0.0058 0.0096 0.0094
Mycobacterium leprae putative cytochrome p450 0.004 0.0054 0.08
Echinococcus granulosus Fatty aldehyde dehydrogenase 0.0017 0.0002 0.0002
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.0057 0.0057
Brugia malayi Cytochrome P450 family protein 0.0156 0.0321 0.0321
Mycobacterium ulcerans methylmalonate semialdehyde dehydrogenase, MmsA 0.0017 0.0002 0.0031
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.004 0.0054 0.0819
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0151 0.0309 0.3726
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0041 0.0057 0.0057
Trypanosoma cruzi pyrroline-5-carboxylate synthetase-like protein, putative 0.0017 0.0002 0.0025
Onchocerca volvulus 0.0378 0.0828 0.3871
Schistosoma mansoni aldehyde dehydrogenase 0.0017 0.0002 0.0002
Echinococcus granulosus cpg binding protein 0.0121 0.024 0.024
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0011
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0077 0.0933
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0011 0.013
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.008 0.0964
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.004 0.0054 0.0264
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0008 0.0008
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0378 0.0828 1
Brugia malayi beta-lactamase family protein 0.0144 0.0292 0.0292
Trypanosoma cruzi glycerol uptake protein, putative 0.0378 0.0828 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0041 0.0057 0.0057
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0017 0.0002 0.001
Leishmania major aldehyde dehydrogenase, putative 0.0017 0.0002 0.0025
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0006
Loa Loa (eye worm) MBOAT family protein 0.0378 0.0828 0.0826
Schistosoma mansoni aldehyde dehydrogenase 0.0306 0.0664 0.0664
Echinococcus multilocularis dnaJ subfamily B 0.1229 0.2778 0.2778
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0067 0.0067
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0151 0.0309 0.0309
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0006 0.0004
Brugia malayi photoreceptor-specific nuclear receptor 0.0041 0.0057 0.0057
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0041 0.0057 0.0057
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.004 0.0054 0.0819
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0041 0.0057 0.0258
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0051 0.0775
Trichomonas vaginalis D-aminoacylase, putative 0.0144 0.0292 0.1368
Brugia malayi hypothetical protein 0.004 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0018 0.0005 0.0003
Onchocerca volvulus 0.0019 0.0008 0.0026
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0017 0.0002 0.0025
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.0303 0.0657 0.9887
Trypanosoma brucei protein kinase, putative 0.0103 0.02 0.2416
Schistosoma mansoni nuclear receptor 0.0019 0.0008 0.0008
Brugia malayi hypothetical protein 0.0019 0.0008 0.0008
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0051 0.0622
Entamoeba histolytica acetyltransferase, GNAT family 0.0041 0.0058 0.0678
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0144 0.0292 0.4399
Echinococcus granulosus o acyltransferase membrane bound domain 0.0378 0.0828 0.0828
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0023 0.0107
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0059 0.0712
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0006 0.0078
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0006
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0181 0.0378 0.0378
Mycobacterium ulcerans aldehyde dehydrogenase (NAD+) dependent 0.0017 0.0002 0.0031
Schistosoma mansoni transcription factor LCR-F1 0.0181 0.0378 0.0378
Echinococcus granulosus dna polymerase eta 0.0019 0.0006 0.0006
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0115 0.0227 0.0227
Plasmodium vivax ornithine aminotransferase, putative 0.0043 0.0062 0.0749
Schistosoma mansoni steroid hormone receptor ad4bp 0.0041 0.0057 0.0057
Mycobacterium tuberculosis Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-at) 0.0043 0.0062 0.0301
Loa Loa (eye worm) hypothetical protein 0.0041 0.0057 0.0055
Brugia malayi hypothetical protein 0.009 0.0169 0.0169
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0041 0.0057 0.0055
Echinococcus granulosus importin subunit beta 1 0.0028 0.0028 0.0028
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0378 0.0828 0.0828
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0041 0.0057 0.0057
Echinococcus multilocularis Aminotransferase class III 0.0043 0.0062 0.0062
Echinococcus multilocularis neuropeptide s receptor 0.0485 0.1074 0.1074
Schistosoma mansoni DNA polymerase eta 0.0019 0.0006 0.0006
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0378 0.0828 0.0828
Echinococcus multilocularis ecdysone induced protein 78C 0.0041 0.0057 0.0057
Toxoplasma gondii methylmalonate-semialdehyde dehydrogenase [acylating], putative 0.0017 0.0002 0.0025
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.004 0.0054 0.0264
Leishmania major trypanothione reductase 0.0046 0.0069 0.0831
Schistosoma mansoni ran 0.0021 0.0011 0.0011
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0021 0.0011 0.0011
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.4381 1 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0008 0.0006
Chlamydia trachomatis glutamate-1-semialdehyde-2,1-aminomutase 0.0043 0.0062 1
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0059 0.0712
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0122 0.0242 0.0242
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.004 0.0054 0.0264
Schistosoma mansoni nuclear receptor nhr-48 0.0019 0.0008 0.0008
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0077 0.0933
Schistosoma mansoni polycystin 1-related 0.004 0.0056 0.0056
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.004 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0011
Leishmania major cytochrome p450-like protein 0.004 0.0054 0.0657
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0144 0.0292 0.0292
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.02 0.0937
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.004 0.0054 0.0819
Loa Loa (eye worm) hypothetical protein 0.0144 0.0292 0.029
Schistosoma mansoni eyes absent homolog 0.009 0.0169 0.0169
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0051 0.0622
Loa Loa (eye worm) hypothetical protein 0.005 0.0077 0.0075
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0378 0.0828 0.0828
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0276 0.0595 0.0595
Echinococcus granulosus Nuclear hormone receptor HR96 0.0019 0.0008 0.0008
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0041 0.0057 0.0057
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0378 0.0828 0.0828
Echinococcus granulosus thyroid hormone receptor alpha 0.0019 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0041 0.0057 0.0055
Toxoplasma gondii ABC1 family protein 0.0144 0.0292 0.3528
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0059 0.0712
Brugia malayi RNA, U transporter 1 0.008 0.0146 0.0146
Echinococcus multilocularis tumor protein p63 0.0335 0.073 0.073
Schistosoma mansoni succinate semialdehyde dehydrogenase 0.0017 0.0002 0.0002

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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